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Nazareno Paolocci

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Chaoqin Xie; Miguel A Aon; Nora Biary; Justin Kauffman; Nazareno Paolocci; Carlo G Tocchetti; Fadi G Akar
Glutathione oxidation unmasks proarrhythmic vulnerability of chronically hyperglycemic guinea pigs.
Mazen Kurdi; Nazareno Paolocci; Vidhya Sivakumaran; Miguel A Aon; Roy J. Duhe; George W Booz
Depletion of cellular glutathione modulates LIF-induced JAK1-STAT3 signaling in cardiac myocytes.
Carlo G Tocchetti; WALTER WATSON; Chaoqin Xie; Fadi G Akar; Viviane Caceres; Sonia Cortassa; Brian O'Rourke; Nazareno Paolocci; Sa Shi; Regina C Spadari-Bratfisch; Brian A Stanley; Miguel A Aon
GSH or palmitate preserves mitochondrial energetic/redox balance, preventing mechanical dysfunction in metabolically challenged myocytes/hearts from type 2 diabetic mice.

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2013: Chaoqin Xie; Miguel A Aon; Nora Biary; Justin Kauffman; Nazareno Paolocci; Carlo G Tocchetti; Fadi G Akar
Glutathione oxidation unmasks proarrhythmic vulnerability of chronically hyperglycemic guinea pigs.
American journal of physiology. Heart and circulatory physiology 2013;304(7):H916-26.
2012: Mazen Kurdi; Nazareno Paolocci; Vidhya Sivakumaran; Miguel A Aon; Roy J. Duhe; George W Booz
Depletion of cellular glutathione modulates LIF-induced JAK1-STAT3 signaling in cardiac myocytes.
The international journal of biochemistry & cell biology 2012;44(12):2106-15.
2012: Carlo G Tocchetti; WALTER WATSON; Chaoqin Xie; Fadi G Akar; Viviane Caceres; Sonia Cortassa; Brian O'Rourke; Nazareno Paolocci; Sa Shi; Regina C Spadari-Bratfisch; Brian A Stanley; Miguel A Aon
GSH or palmitate preserves mitochondrial energetic/redox balance, preventing mechanical dysfunction in metabolically challenged myocytes/hearts from type 2 diabetic mice.
Diabetes 2012;61(12):3094-105.
2012: Wei Dong Gao; S Bruce King; Christopher I Murray; Xiaoxu Shen; Brian A Stanley; Ye Tian; Jennifer E Van Eyk; David A Wink; Xin Zhong; Jenna F DuMond; Darren Foster; Nazareno Paolocci
Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function.
Circulation research 2012;111(8):1002-11.
2012: Miguel A Aon; Jackelyn Melissa Kembro; Brian O'Rourke; Nazareno Paolocci; Vidhya Sivakumaran; Brian Alan Stanley; Sonia Cortassa
Glutathione/thioredoxin systems modulate mitochondrial H2O2 emission: an experimental-computational study.
The Journal of general physiology 2012;139(6):479-91.
2012: Xiaolin Niu; Nazareno Paolocci; Vidhya Sivakumaran; Konrad Vandegaer; Vabren L Watts; Djahida Bedja; Oscar Horacio Cingolani; Carla L Ellis; Kathleen L Gabrielson; David A Kass; Jordan S Leyton-Mange; Karen L Miller; Lili A Barouch
Cardioprotective effect of beta-3 adrenergic receptor agonism: role of neuronal nitric oxide synthase.
Journal of the American College of Cardiology 2012;59(22):1979-87.
2012: Ashish Gupta; Gary Gerstenblith; Shenghan Lai; Sa Shi; Nazareno Paolocci; CHARLES STEENBERGEN; Viviane Caceres; Michelle K Leppo; Jason Su; Yibin Wang; Darren Foster; Jonathan A Kirk; Vadappuram P Chacko; Ashwin Akki; Robert G Weiss
Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved.
The Journal of clinical investigation 2012;122(1):291-302.
2012: Carlos Zgheib; Joe Zgheib; Fouad A Zouein; Barak W Gunter; S Bruce King; Mazen Kurdi; Nazareno Paolocci; Damian G Romero; Brian A Stanley; George W Booz
Acyloxy nitroso compounds inhibit LIF signaling in endothelial cells and cardiac myocytes: evidence that STAT3 signaling is redox-sensitive.
PloS one 2012;7(8):e43313.
2012: Stephanie M J Fliedner; Zuzana Hajkova; Hana Hansikova; Xiao-Sheng Jiang; Ivana Jochmanova; Nina Kaludercic; Hendrik Lehnert; Nikoletta K Lendvai; Andrea Limpuangthip; Lucia Martiniova; Nazareno Paolocci; Forbes D Porter; Jana Sladkova; Arthur S Tischler; Robert Wesley; Alfred L Yergey; Jiri Zeman; Peter S Backlund; Jan Breza; Karel Pacak
Warburg effect's manifestation in aggressive pheochromocytomas and paragangliomas: insights from a mouse cell model applied to human tumor tissue.
PloS one 2012;7(7):e40949.
2012: Jian Cao; Antonio L'Abbate; Giuseppe Lazzarino; Pellegrino Masiello; Danilo Neglia; Michela Novelli; Nazareno Paolocci; Nitin Puri; Barbara Tavazzi; Cecilia Vecoli; Yu-Tang Wang; Nader G Abraham
Cobalt-Protoporphyrin Improves Heart Function by Blunting Oxidative Stress and Restoring NO Synthase Equilibrium in an Animal Model of Experimental Diabetes.
Frontiers in physiology 2012;3():160.
2011: Wengang Ding; S Bruce King; Zhitao Li; Jackie L Martin; Nazareno Paolocci; Xiaoxu Shen; Vidhya Sivakumaran; Wei Dong Gao
Reversal of isoflurane-induced depression of myocardial contraction by nitroxyl via myofilament sensitization to Ca2+.
The Journal of pharmacology and experimental therapeutics 2011;339(3):825-31.
2011: Brian A Stanley; WALTER WATSON; Sa Shi; Vidhya Sivakumaran; Miguel A Aon; David Lloyd; Iain McDonald; Nazareno Paolocci
Thioredoxin reductase-2 is essential for keeping low levels of H(2)O(2) emission from isolated heart mitochondria.
The Journal of biological chemistry 2011;286(38):33669-77.
2011: Cecilia Vecoli; Djahida Bedja; J Cao; K K Gabrielson; K Inoue; Antonio L'Abbate; Danilo Neglia; Nazareno Paolocci; K Sodhi; L Vanella; Nader G Abraham
Apolipoprotein A-I mimetic peptide L-4F prevents myocardial and coronary dysfunction in diabetic mice.
Journal of cellular biochemistry 2011;112(9):2616-26.
2011: Nina Kaludercic; Andrea Carpi; Roberta Menabò; Fabio Di Lisa; Nazareno Paolocci
Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury.
Biochimica et biophysica acta 2011;1813(7):1323-32.
2011: Carlo G Tocchetti; Brian A Stanley; Christopher I Murray; Vidhya Sivakumaran; Sonia Donzelli; Daniele Mancardi; Pasquale Pagliaro; Wei Dong Gao; Jennifer E Van Eyk; David A Kass; David A Wink; Nazareno Paolocci
Playing with cardiac "redox switches": the "HNO way" to modulate cardiac function.
Antioxidants & redox signaling 2011;14(9):1687-98.
2011: Wilmarie Flores-Santana; Debra J Salmon; Sonia Donzelli; Christopher H Switzer; Debashree Basudhar; Lisa A Ridnour; Robert Cheng; Sharon Anneve Glynn; Nazareno Paolocci; Jon M Fukuto; Katrina M Miranda; David A Wink
The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems.
Antioxidants & redox signaling 2011;14(9):1659-74.
2011: Fabio Di Lisa; Nina Kaludercic; Nazareno Paolocci
β₂-Adrenoceptors, NADPH oxidase, ROS and p38 MAPK: another 'radical' road to heart failure?
British journal of pharmacology 2011;162(5):1009-11.
2011: Oscar Horacio Cingolani; Nina Kaludercic; Nazareno Paolocci
Sexual dimorphism in cardiac norepinephrine spillover: a NET difference.
Heart (British Cardiac Society) 2011;97(5):347-9.
2010: Bruce D Carter; Ning Feng; Nazareno Paolocci
The p75 neurotrophin receptor, semaphorins, and sympathetic traffic in the heart.
American journal of physiology. Heart and circulatory physiology 2010;298(6):H1633-6.
2010: Giulio Agnetti; Nina Kaludercic; Lesley A Kane; Steven T Elliott; Yurong Guo; Khalid Chakir; Daya Samantapudi; Nazareno Paolocci; Gordon F Tomaselli; David A Kass; Jennifer E Van Eyk
Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts.
Circulation. Cardiovascular genetics 2010;3(1):78-87.
2010: Nina Kaludercic; Eiki Takimoto; Takahiro Nagayama; Ning Feng; Edwin W Lai; Djahida Bedja; Kevin Chen; Kathleen L Gabrielson; Randy D Blakely; Jean C Shih; Karel Pacak; David A Kass; Fabio Di Lisa; Nazareno Paolocci
Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload.
Circulation research 2010;106(1):193-202.
2010: Mark J Kohr; Nina Kaludercic; Carlo G Tocchetti; Wei Dong Gao; David A Kass; Paul Janssen; Nazareno Paolocci; Mark T Ziolo
Nitroxyl enhances myocyte Ca2+ transients by exclusively targeting SR Ca2+-cycling.
Frontiers in bioscience (Elite edition) 2010;2():614-26.
2009: Christopher H Switzer; Wilmarie Flores-Santana; Daniele Mancardi; Sonia Donzelli; Debashree Basudhar; Lisa A Ridnour; Katrina M Miranda; Jon M Fukuto; Nazareno Paolocci; David A Wink
The emergence of nitroxyl (HNO) as a pharmacological agent.
Biochimica et biophysica acta 2009;1787(7):835-40.
2009: Nazareno Paolocci; David A Wink
The shy Angeli and his elusive creature: the HNO route to vasodilation.
American journal of physiology. Heart and circulatory physiology 2009;296(5):H1217-20.
2009: Nina Kaludercic; Carlo Reggiani; Nazareno Paolocci
Genes, geography and geometry: the "critical mass" in hypertrophic cardiomyopathy.
The Journal of molecular diagnostics : JMD 2009;11(1):12-6.
2008: Jeffrey P Froehlich; James E Mahaney; Gizem Keceli; Christopher M Pavlos; Russell Goldstein; Abiona J Redwood; Carlota Sumbilla; Dong I Lee; Carlo G Tocchetti; David A Kass; Nazareno Paolocci; John P Toscano
Phospholamban thiols play a central role in activation of the cardiac muscle sarcoplasmic reticulum calcium pump by nitroxyl.
Biochemistry 2008;47(50):13150-2.
2008: Jennifer L Hoard; Donald B Hoover; A M Mabe; Randy D Blakely; N Feng; Nazareno Paolocci
Cholinergic neurons of mouse intrinsic cardiac ganglia contain noradrenergic enzymes, norepinephrine transporters, and the neurotrophin receptors tropomyosin-related kinase A and p75.
Neuroscience 2008;156(1):129-42.
2008: Douglas D Thomas; Lisa A Ridnour; Jeffrey S Isenberg; Wilmarie Flores-Santana; Christopher H Switzer; Sonia Donzelli; Dr.P Hussain; Cecilia Vecoli; Nazareno Paolocci; Stefan Ambs; Carol A. Colton; Curtis C Harris; David D Roberts; David A Wink
The chemical biology of nitric oxide: implications in cellular signaling.
Free radical biology & medicine 2008;45(1):18-31.
2008: An L Moens; Eiki Takimoto; Carlo G Tocchetti; Khalid Chakir; Djahida Bedja; Gianfranco Cormaci; Elizabeth A Ketner; Maulik Majmudar; Kathleen L Gabrielson; Marc K Halushka; James B Mitchell; Shyam Biswal; Keith M Channon; Michael S Wolin; Nicholas J Alp; Nazareno Paolocci; Hunter C Champion; David A Kass
Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy.
Circulation 2008;117(20):2626-36.
2008: An L Moens; Hunter C Champion; Marc J Claeys; Barbara Tavazzi; Pawel M Kaminski; Michael S Wolin; Dirk J Borgonjon; Luc Van Nassauw; Azeb Haile; Menekhem M Zviman; Djahida Bedja; Floris L Wuyts; Rebecca S Elsaesser; Paul Cos; Kathleen L Gabrielson; Giuseppe Lazzarino; Nazareno Paolocci; Jean-Pierre Timmermans; Christiaan Vrints; David A Kass
High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury.
Circulation 2008;117(14):1810-9.
2008: David A Wink; Nazareno Paolocci
Mother was right: eat your vegetables and do not spit! When oral nitrate helps with high blood pressure.
Hypertension 2008;51(3):617-9.
2008: Cecilia Vecoli; Nazareno Paolocci
When the heart sleeps... is the vagus resetting the myocardial 'redox clock'?
Cardiovascular research 2008;77(4):609-11.
2008: Nina Kaludercic; Merry Lindsey; Barbara Tavazzi; Giuseppe Lazzarino; Nazareno Paolocci
Inhibiting metalloproteases with PD 166793 in heart failure: impact on cardiac remodeling and beyond.
Cardiovascular therapeutics 2008;26(1):24-37.
2008: Jon M Fukuto; Matthew I Jackson; Nina Kaludercic; Nazareno Paolocci
Examining nitroxyl in biological systems.
Methods in enzymology 2008;440():411-31.
2007: Ning Feng; Donald B Hoover; Nazareno Paolocci
Forever young?: nerve growth factor, sympathetic fibers, and right ventricle pressure overload.
Circulation research 2007;100(12):1670-2.
2007: Tieying Dai; Ye Tian; Carlo G Tocchetti; Tatsuo Katori; Anne M Murphy; David A Kass; Nazareno Paolocci; Wei Dong Gao
Nitroxyl increases force development in rat cardiac muscle.
The Journal of physiology 2007;580(Pt.3):951-60.
2007: Nazareno Paolocci; Matthew I Jackson; Brenda E Lopez; Katrina M Miranda; Carlo G Tocchetti; David A Wink; Adrian J Hobbs; Jon M Fukuto
The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO.
Pharmacology & therapeutics 2007;113(2):442-58.
2007: Carlo G Tocchetti; Wang Wang; Jeffrey P Froehlich; Sabine Huke; Miguel A Aon; Gerald M Wilson; Giulietta Di Benedetto; Brian O'Rourke; Wei Dong Gao; David A Wink; John P Toscano; Manuela Zaccolo; Donald M Bers; Hector H Valdivia; Heping Cheng; David A Kass; Nazareno Paolocci
Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling.
Circulation research 2007;100(1):96-104.
2006: Tatsuo Katori; Sonia Donzelli; Carlo G Tocchetti; Katrina M Miranda; Gianfrancesco Cormaci; Douglas D Thomas; Elizabeth A Ketner; Myung Jae Lee; Daniele Mancardi; David A Wink; David A Kass; Nazareno Paolocci
Peroxynitrite and myocardial contractility: in vivo versus in vitro effects.
Free radical biology & medicine 2006;41(10):1606-18.
2006: Nazareno Paolocci; Barbara Tavazzi; Roberto Biondi; Yehezkiel A Gluzband; Angela Maria Amorini; Carlo G Tocchetti; Mehrdad Hejazi; Patrizio Caturegli; Jan Kajstura; Giuseppe Lazzarino; David A Kass
Metalloproteinase inhibitor counters high-energy phosphate depletion and AMP deaminase activity enhancing ventricular diastolic compliance in subacute heart failure.
The Journal of pharmacology and experimental therapeutics 2006;317(2):506-13.
2006: Sonia Donzelli; Michael G Espey; Douglas D Thomas; Daniele Mancardi; Carlo G Tocchetti; Lisa A Ridnour; Nazareno Paolocci; S Bruce King; Katrina M Miranda; Giuseppe Lazzarino; Jon M Fukuto; David A Wink
Discriminating formation of HNO from other reactive nitrogen oxide species.
Free radical biology & medicine 2006;40(6):1056-66.
2006: Marco Mongillo; Carlo G Tocchetti; Anna Terrin; Valentina Lissandron; York-Fong Cheung; Wolfgang R Dostmann; Tullio Pozzan; David A Kass; Nazareno Paolocci; Miles D Houslay; Manuela Zaccolo
Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway.
Circulation research 2006;98(2):226-34.
2005: Katrina M Miranda; Tatsuo Katori; Claudia L Torres de Holding; Lynta Thomas; Lisa A Ridnour; William J McLendon; Stephanie M Cologna; Andrew S Dutton; Hunter C Champion; Daniele Mancardi; Carlo G Tocchetti; Joseph E Saavedra; Larry K Keefer; Kendall N Houk; Jon M Fukuto; David A Kass; Nazareno Paolocci; David A Wink
Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo.
Journal of medicinal chemistry 2005;48(26):8220-8.
2005: Nazareno Paolocci
Peroxynitrite like Pan?
Cardiovascular research 2005;67(2):176-8.
2005: Jon M Fukuto; Michael D Bartberger; Andrew S Dutton; Nazareno Paolocci; David A Wink; Kendall N Houk
The physiological chemistry and biological activity of nitroxyl (HNO): the neglected, misunderstood, and enigmatic nitrogen oxide.
Chemical research in toxicology 2005;18(5):790-801.
2005: Eiki Takimoto; Hunter C Champion; Manxiang Li; Shuxun Ren; E Rene Rodriguez; Barbara Tavazzi; Giuseppe Lazzarino; Nazareno Paolocci; Kathleen L Gabrielson; Yibin Wang; David A Kass
Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load.
The Journal of clinical investigation 2005;115(5):1221-31.
2005: Tatsuo Katori; Donald B Hoover; Jeffrey L Ardell; Robert H Helm; Diego F Belardi; Carlo G Tocchetti; Paul R Forfia; David A Kass; Nazareno Paolocci
Calcitonin gene-related peptide in vivo positive inotropy is attributable to regional sympatho-stimulation and is blunted in congestive heart failure.
Circulation research 2005;96(2):234-43.
2005: Katrina M Miranda; Andrew S Dutton; Lisa A Ridnour; Christian A Foreman; Eleonora Ford; Nazareno Paolocci; Tatsuo Katori; Carlo G Tocchetti; Daniele Mancardi; Douglas D Thomas; Michael G Espey; Kendall N Houk; Jon M Fukuto; David A Wink
Mechanism of aerobic decomposition of Angeli's salt (sodium trioxodinitrate) at physiological pH.
Journal of the American Chemical Society 2005;127(2):722-31.
2004: Daniele Mancardi; Lisa A Ridnour; Douglas D Thomas; Tatsuo Katori; Carlo G Tocchetti; Michael G Espey; Katrina M Miranda; Nazareno Paolocci; David A Wink
The chemical dynamics of NO and reactive nitrogen oxides: a practical guide.
Current molecular medicine 2004;4(7):723-40.
2004: Lisa A Ridnour; Douglas D Thomas; Daniele Mancardi; Michael G Espey; Katrina M Miranda; Nazareno Paolocci; Martin Feelisch; Jon M Fukuto; David A Wink
The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations.
Biological chemistry 2004;385(1):1-10.
2003: David A Wink; Katrina M Miranda; Tatsuo Katori; Daniele Mancardi; Douglas D Thomas; Lisa A Ridnour; Michael G Espey; Martin Feelisch; Carol A. Colton; Jon M Fukuto; Pasquale Pagliaro; David A Kass; Nazareno Paolocci
Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm.
American journal of physiology. Heart and circulatory physiology 2003;285(6):H2264-76.
2003: Katrina M Miranda; Nazareno Paolocci; Tatsuo Katori; Douglas D Thomas; Eleonora Ford; Michael D Bartberger; Michael G Espey; David A Kass; Martin Feelisch; Jon M Fukuto; David A Wink
A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(16):9196-201.
2003: R Biondi; C Tassi; R Rossi; C Benedetti; C Ferranti; Nazareno Paolocci; I Parisse; F De Bellis; E Capodicasa
Changes in plasma level of human leukocyte elastase during leukocytosis from physical effort.
Immunopharmacology and immunotoxicology 2003;25(3):385-96.
2003: Wei-Ping Qiu; Qinghua Hu; Nazareno Paolocci; Roy C Ziegelstein; David A Kass
Differential effects of pulsatile versus steady flow on coronary endothelial membrane potential.
American journal of physiology. Heart and circulatory physiology 2003;285(1):H341-6.
2003: Nazareno Paolocci; Tatsuo Katori; Hunter C Champion; Marcus E St John; Katrina M Miranda; Jon M Fukuto; David A Wink; David A Kass
Positive inotropic and lusitropic effects of HNO/NO- in failing hearts: independence from beta-adrenergic signaling.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5537-42.
2003: Takayoshi Isoda; Nazareno Paolocci; Kobra Haghighi; Congrong Wang; Yibin Wang; Dimitrios Georgakopoulos; Giuseppe Servillo; Maria Agnese Della Fazia; Evangelia G Kranias; Anna A DePaoli-Roach; Paolo Sassone-Corsi; David A Kass
Novel regulation of cardiac force-frequency relation by CREM (cAMP response element modulator).
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(2):144-51.
2003: Katrina M Miranda; Raymond W Nims; Douglas D Thomas; Michael G Espey; Deborah Citrin; Michael D Bartberger; Nazareno Paolocci; Jon M Fukuto; Martin Feelisch; David A Wink
Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins. A chemical discussion of the differential biological effects of these redox related products of NOS.
Journal of inorganic biochemistry 2003;93(1-2):52-60.
2003: Pasquale Pagliaro; Daniele Mancardi; Raffaella Rastaldo; Claudia Penna; Donatella Gattullo; Katrina M Miranda; Martin Feelisch; David A Wink; David A Kass; Nazareno Paolocci
Nitroxyl affords thiol-sensitive myocardial protective effects akin to early preconditioning.
Free radical biology & medicine 2003;34(1):33-43.
2002: Trinity J Bivalacqua; Albert L Hyman; Philip J Kadowitz; Nazareno Paolocci; David A Kass; Hunter C Champion
Role of calcitonin gene-related peptide (CGRP) in chronic hypoxia-induced pulmonary hypertension in the mouse. Influence of gene transfer in vivo.
Regulatory peptides 2002;108(2-3):129-33.
2002: Walter F Saavedra; Richard S Tunin; Nazareno Paolocci; Takayuki Mishima; George Suzuki; Charles W Emala; Pervaiz A Chaudhry; Petros V Anagnostopoulos; Ramesh Gupta; Hani N Sabbah; David A Kass
Reverse remodeling and enhanced adrenergic reserve from passive external support in experimental dilated heart failure.
Journal of the American College of Cardiology 2002;39(12):2069-76.
2002: Walter F Saavedra; Nazareno Paolocci; Marcus E St John; Michel W Skaf; Garrick C Stewart; Jin-Sheng Xie; Robert W Harrison; Joshua Zeichner; Daniel Mudrick; Eduardo Marban; David A Kass; Joshua M Hare
Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart.
Circulation research 2002;90(3):297-304.
2002: Walter F Saavedra; Nazareno Paolocci; David A Kass
Effects of cardioselective KATP channel antagonism on basal, stimulated, and ischaemic myocardial function in in vivo failing canine heart.
British journal of pharmacology 2002;135(3):657-62.
2002: Douglas D Thomas; Katrina M Miranda; Michael G Espey; Deborah Citrin; David Jourd'heuil; Nazareno Paolocci; Sandra J Hewett; Carol A. Colton; Matthew B Grisham; Martin Feelisch; David A Wink
Guide for the use of nitric oxide (NO) donors as probes of the chemistry of NO and related redox species in biological systems.
Methods in enzymology 2002;359():84-105.
2001: Nazareno Paolocci; Walter F Saavedra; Katrina M Miranda; C Martignani; Takayoshi Isoda; Joshua M Hare; Michael G Espey; Jon M Fukuto; Martin Feelisch; David A Wink; David A Kass
Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10463-8.
2001: H Senzaki; Carolyn J Smith; George J Juang; Takayoshi Isoda; Sharon R Pine; A Ohler; Nazareno Paolocci; Gordon F Tomaselli; Joshua M Hare; David A Kass
Cardiac phosphodiesterase 5 (cGMP-specific) modulates beta-adrenergic signaling in vivo and is down-regulated in heart failure.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1718-26.
2001: Raffaella Rastaldo; Nazareno Paolocci; Amedeo Chiribiri; Claudia Penna; Donatella Gattullo; Pasquale Pagliaro
Cytochrome P-450 metabolite of arachidonic acid mediates bradykinin-induced negative inotropic effect.
American journal of physiology. Heart and circulatory physiology 2001;280(6):H2823-32.
2001: Nazareno Paolocci; Roberto Biondi; Marco Bettini; C I Lee; C O Berlowitz; Ruggero Rossi; Y Xia; Giuseppe Ambrosio; A L'Abbate; David A Kass; Jay L Zweier
Oxygen radical-mediated reduction in basal and agonist-evoked NO release in isolated rat heart.
Journal of molecular and cellular cardiology 2001;33(4):671-9.
2001: Roberto Biondi; Y Xia; Ruggero Rossi; Nazareno Paolocci; Giuseppe Ambrosio; Jay L Zweier
Detection of hydroxyl radicals by D-phenylalanine hydroxylation: a specific assay for hydroxyl radical generation in biological systems.
Analytical biochemistry 2001;290(1):138-45.
2001: Nazareno Paolocci; Pasquale Pagliaro; Takayoshi Isoda; F W Saavedra; David A Kass
Role of calcium-sensitive K(+) channels and nitric oxide in in vivo coronary vasodilation from enhanced perfusion pulsatility.
Circulation 2001;103(1):119-24.
2000: Nazareno Paolocci; UE Ekelund; Takayoshi Isoda; Michitaka Ozaki; Koenraad Vandegaer; Dimitrios Georgakopoulos; Robert W Harrison; David A Kass; Joshua M Hare
cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation.
American journal of physiology. Heart and circulatory physiology 2000;279(4):H1982-8.
2000: H Senzaki; Nazareno Paolocci; Yehezkiel A Gluzband; Merry Lindsey; Joseph S Janicki; Michael T Crow; David A Kass
beta-blockade prevents sustained metalloproteinase activation and diastolic stiffening induced by angiotensin II combined with evolving cardiac dysfunction.
Circulation research 2000;86(7):807-15.
2000: Pasquale Pagliaro; Raffaella Rastaldo; Nazareno Paolocci; Donatella Gattullo; Gianni Losano
The endothelium-derived hyperpolarizing factor: does it play a role in vivo and is it involved in the regulation of vascular tone only?
Italian heart journal : official journal of the Italian Federation of Cardiology 2000;1(4):264-8.
2000: H Senzaki; Takayoshi Isoda; Nazareno Paolocci; UE Ekelund; Joshua M Hare; David A Kass
Improved mechanoenergetics and cardiac rest and reserve function of in vivo failing heart by calcium sensitizer EMD-57033.
Circulation 2000;101(9):1040-8.
2000: Pasquale Pagliaro; Nazareno Paolocci; Takayoshi Isoda; Walter F Saavedra; G Sunagawa; David A Kass
Reversal of glibenclamide-induced coronary vasoconstriction by enhanced perfusion pulsatility: possible role for nitric oxide.
Cardiovascular research 2000;45(4):1001-9.
1999: Pasquale Pagliaro; H Senzaki; Nazareno Paolocci; Takayoshi Isoda; G Sunagawa; FA Recchia; David A Kass
Specificity of synergistic coronary flow enhancement by adenosine and pulsatile perfusion in the dog.
The Journal of physiology 1999;520 Pt 1():271-80.
1998: A Dovas; Maria Luisa Lucchi; Ruggero Bortolami; Annamaria Grandis; A R Palladino; E Banelli; M Carretta; F Magni; Nazareno Paolocci
Collaterals of recurrent laryngeal nerve fibres innervate the thymus: a fluorescent tracer and HRP investigation of efferent vagal neurons in the rat brainstem.
Brain research 1998;809(2):141-8.
1998: Roberto Biondi; Nazareno Paolocci; R Spaccapanico; Marco Bettini; T Cantalupo; G Brugnami; Enrico Capodicasa
Endothelin-1 and NO2/NO3 circulating levels after short-term (1h) oxygen supplementation in patients with chronic respiratory failure during long-term oxygen treatment (LTOT).
Immunopharmacology and immunotoxicology 1998;20(3):433-46.
1998: Nazareno Paolocci; M Sironi; Marco Bettini; G Bartoli; Slawomir Michalak; C Bandi; F Magni; Fabrizio Bruschi
Immunopathological mechanisms underlying the time-course of Trichinella spiralis cardiomyopathy in rats.
Virchows Archiv : an international journal of pathology 1998;432(3):261-6.
1997: Patricolo Mario; A Zangari; Nazareno Paolocci; F Magni; M P Viola-Magni; L A Hernandez-Mena; LG Capuano; Massimo Rivosecchi
In utero partial liver resection in the rabbit model: a study on fetal tissue regeneration.
Fetal diagnosis and therapy 1997;12(4):232-5.
1996: Patricolo Mario; Nazareno Paolocci; A Zangari; A Antonica; L Rossi; F Magni; M P Viola-Magni; Paolo Caione; Alberto Lais; Massimo Rivosecchi
[Hepatic resection in the fetal rabbit. Histologic comparison of tissue regeneration in the fetus versus the adult].
Minerva chirurgica 1996;51(11):971-7.
1996: Alberto Lais; Nazareno Paolocci; Fabio Ferro; C Bosman; Renata Boldrini; Paolo Caione
Morphometric analysis of smooth muscle in the exstrophy-epispadias complex.
The Journal of urology 1996;156(2 Pt 2):819-21.
1996: A Antonica; E Ayroldi; F Magni; Nazareno Paolocci
Lymphocyte traffic changes induced by monolateral vagal denervation in mouse thymus and peripheral lymphoid organs.
Journal of neuroimmunology 1996;64(2):115-22.
1994: A Antonica; F Magni; Luigi Mearini; Nazareno Paolocci
Vagal control of lymphocyte release from rat thymus.
Journal of the autonomic nervous system 1994;48(3):187-97.
1994: F Magni; G Panduri; Nazareno Paolocci
Hypothermia triggers iron-dependent lipoperoxidative damage in the isolated rat heart.
Free radical biology & medicine 1994;16(4):465-76.