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Thomas Pap

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Anatomy

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Signal Transduction

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Otto Lindemann; Thomas Pap; Sandra Schimmelpfennig; Jessica Bertrand; Alexander Dietrich; Anke Fabian; Svetlana Frank; Peter J Hanley; Daniel Umlauf; Albrecht Schwab
TRPC6 Regulates CXCR2-Mediated Chemotaxis of Murine Neutrophils.
Jessica Bertrand; Peter Bruckner; Francesco Dell'Accio; Frank Echtermeyer; Lars Godmann; Heriburg Hidding; Giovanna Nalesso; Thomas Pap; Michael J Raschke; Richard Stange; Melanie Timmen; Rita Dreier
Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice.
Thomas Pap; Jessica Bertrand
Syndecans in cartilage breakdown and synovial inflammation.

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2013: Otto Lindemann; Thomas Pap; Sandra Schimmelpfennig; Jessica Bertrand; Alexander Dietrich; Anke Fabian; Svetlana Frank; Peter J Hanley; Daniel Umlauf; Albrecht Schwab
TRPC6 Regulates CXCR2-Mediated Chemotaxis of Murine Neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(11):5496-505.
2013: Jessica Bertrand; Peter Bruckner; Francesco Dell'Accio; Frank Echtermeyer; Lars Godmann; Heriburg Hidding; Giovanna Nalesso; Thomas Pap; Michael J Raschke; Richard Stange; Melanie Timmen; Rita Dreier
Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice.
Arthritis and rheumatism 2013;65(3):743-52.
2013: Thomas Pap; Jessica Bertrand
Syndecans in cartilage breakdown and synovial inflammation.
Nature reviews. Rheumatology 2013;9(1):43-55.
2012: Anke Fabian; Otto Lindemann; Thomas Pap; Jessica Bertrand; Albrecht Schwab
Transient receptor potential canonical channel 1 impacts on mechanosignaling during cell migration.
Pflügers Archiv : European journal of physiology 2012;464(6):623-30.
2012: J Bertrand; Francesco Dell'Accio; Martin Fuerst; S Hermann; G Nalesso; Yvonne Nitschke; W Ruether; Frank Rutsch; M Schäfers; J Sherwood; Thomas Pap
Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice.
Annals of the rheumatic diseases 2012;71(7):1249-53.
2012: Marvin A Peters; Noreen Pundt; Simon Strietholt; Wim B van den Berg; Doreen Wendholt; Beate Eckes; Svetlana Frank; Leo A B Joosten; George Kollias; Adelheid Korb-Pap; Thomas Pap
The loss of α2β1 integrin suppresses joint inflammation and cartilage destruction in mouse models of rheumatoid arthritis.
Arthritis and rheumatism 2012;64(5):1359-68.
2012: Christian Schmidt-Lauber; Aleksandra Sindic; Marion Victor; Jessica Bertrand; Stefan-Martin Brand; Bayram Edemir; Meike Fischer; Manfred Fobker; Uwe Hansen; Saliha Harrach; Marianne Heitzmann; Thomas Pap; Hermann Pavenstädt; Eberhard Schlatter; Giuliano Ciarimboli
Transport mechanisms and their pathology-induced regulation govern tyrosine kinase inhibitor delivery in rheumatoid arthritis.
PloS one 2012;7(12):e52247.
2012: Frans van Valen; Thomas Pap; Uta Dirksen; George Gosheger; Henning Harrer; Marc Hotfilder; Hans-Ulrich Humpf; Heribert Jürgens
A Novel Role of IGF1 in Apo2L/TRAIL-Mediated Apoptosis of Ewing Tumor Cells.
Sarcoma 2012;2012():782970.
2011: Thomas Vordemvenne; Rene Hartensuer; Jürgen Paletta; Thomas Pap; Michael J Raschke; Sabine Ochman
Cooperative effects in differentiation and proliferation between PDGF-BB and matrix derived synthetic peptides in human osteoblasts.
BMC musculoskeletal disorders 2011;12():263.
2010: Daniel Umlauf; Svetlana Frank; Thomas Pap; Jessica Bertrand
Cartilage biology, pathology, and repair.
Cellular and molecular life sciences : CMLS 2010;67(24):4197-211.
2010: Jessica Bertrand; Christoph Cromme; Daniel Umlauf; Svetlana Frank; Thomas Pap
Molecular mechanisms of cartilage remodelling in osteoarthritis.
The international journal of biochemistry & cell biology 2010;42(10):1594-601.
2010: Marianne Niedermeier; Thomas Pap; Adelheid Korb
Therapeutic opportunities in fibroblasts in inflammatory arthritis.
Best practice & research. Clinical rheumatology 2010;24(4):527-40.
2010: Hanna Maciejewska-Rodrigues; Emmanuel Karouzakis; Simon Strietholt; Hossein Hemmatazad; Michel Neidhart; Caroline Ospelt; Renate E Gay; Beat A Michel; Thomas Pap; Steffen GAY; Astrid Jüngel
Epigenetics and rheumatoid arthritis: the role of SENP1 in the regulation of MMP-1 expression.
Journal of autoimmunity 2010;35(1):15-22.
2010: Thomas Pap
[Current trends in the design and development of monoclonal antibodies against inflammatory mediators for the treatment of rheumatoid arthritis].
Zeitschrift für Rheumatologie 2010;69(1):73-8.
2009: Mariola Kurowska-Stolarska; Jörg H W Distler; Astrid Jüngel; Weronika Rudnicka; Elena Neumann; Thomas Pap; Roland H Wenger; Beat A Michel; Ulf Müller-Ladner; Renate E Gay; Wlodzimierz Maslinski; Steffen GAY; Oliver Distler
Inhibitor of DNA binding/differentiation 2 induced by hypoxia promotes synovial fibroblast-dependent osteoclastogenesis.
Arthritis and rheumatism 2009;60(12):3663-75.
2009: Martin Fuerst; J Bertrand; L Lammers; Rita Dreier; Frank Echtermeyer; Yvonne Nitschke; Frank Rutsch; F K W Schäfer; Oliver Niggemeyer; J Steinhagen; C H Lohmann; Thomas Pap; W Rüther
Calcification of articular cartilage in human osteoarthritis.
Arthritis and rheumatism 2009;60(9):2694-703.
2009: Christina Wunrau; Eva-Maria Schnaeker; Katharina Freyth; Noreen Pundt; Doreen Wendholt; Katja Neugebauer; Uwe Hansen; Thomas Pap; Berno Dankbar
Establishment of a matrix-associated transepithelial resistance invasion assay to precisely measure the invasive potential of synovial fibroblasts.
Arthritis and rheumatism 2009;60(9):2606-11.
2009: Ingmar Meinecke; Géza Pap; Heidi Mendoza; Steffen Drange; Stephan Ender; Simon Strietholt; Renate E Gay; Christine Seyfert; Barbara Ink; Steffen Gay; Thomas Pap; Marvin A Peters
Small ubiquitin-like modifier 1 [corrected] mediates the resistance of prosthesis-loosening fibroblast-like synoviocytes against Fas-induced apoptosis.
Arthritis and rheumatism 2009;60(7):2065-70.
2009: Adelheid Korb; Hermann Pavenstädt; Thomas Pap
Cell death in rheumatoid arthritis.
Apoptosis : an international journal on programmed cell death 2009;14(4):447-54.
2009: Noreen Pundt; Marvin A Peters; Christina Wunrau; Simon Strietholt; Carsten Fehrmann; Katja Neugebauer; Christine Seyfert; Frans van Valen; Thomas Pap; Ingmar Meinecke
Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent.
Arthritis research & therapy 2009;11(1):R16.
2008: Simon Strietholt; Britta Maurer; Marvin A Peters; Thomas Pap; Steffen Gay
Epigenetic modifications in rheumatoid arthritis.
Arthritis research & therapy 2008;10(5):219.
2007: A Korb; M Peters; Ingmar Meinecke; Thomas Pap
[Intracellular signaling pathways of synovial fibroblasts in rheumatoid arthritis].
Zeitschrift für Rheumatologie 2007;66(4):311-6.
2007: Thomas Pap
[Regulation of apoptosis in aggressive fibroblasts].
Zeitschrift für Rheumatologie 2007;66(3):239-40, 242.
2007: Berno Dankbar; Katja Neugebauer; Christina Wunrau; Carsten O Tibesku; Adrian Skwara; Thomas Pap; Susanne Fuchs-Winkelmann
Hepatocyte growth factor induction of macrophage chemoattractant protein-1 and osteophyte-inducing factors in osteoarthritis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2007;25(5):569-77.
2007: Maik Hoberg; Maximilian Rudert; Thomas Pap; Gerd Klein; Steffen GAY; Wilhelm K Aicher
Attachment to laminin-111 facilitates transforming growth factor beta-induced expression of matrix metalloproteinase-3 in synovial fibroblasts.
Annals of the rheumatic diseases 2007;66(4):446-51.
2007: Ingmar Meinecke; Antje Cinski; Anja Baier; Marvin A Peters; Berno Dankbar; Aline Wille; Andreas Drynda; Heidi Mendoza; Renate E Gay; Ron Thomas Hay; Barbara Ink; Steffen Gay; Thomas Pap
Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5073-8.
2007: Ulf Müller-Ladner; Caroline Ospelt; Steffen Gay; Oliver Distler; Thomas Pap
Cells of the synovium in rheumatoid arthritis. Synovial fibroblasts.
Arthritis research & therapy 2007;9(6):223.
2007: Ingmar Meinecke; Edita Rutkauskaite; Antje Cinski; Ulf Müller-Ladner; Steffen Gay; Thomas Pap
Gene transfer to synovial fibroblast: methods and evaluation in the SCID mouse model.
Methods in molecular medicine 2007;135():393-412.
2006: Lars-Henrik Meyer; Lars Franssen; Thomas Pap
The role of mesenchymal cells in the pathophysiology of inflammatory arthritis.
Best practice & research. Clinical rheumatology 2006;20(5):969-81.
2006: Lars C Huber; Oliver Distler; Ingo H Tarner; Renate E Gay; Steffen Gay; Thomas Pap
Synovial fibroblasts: key players in rheumatoid arthritis.
Rheumatology (Oxford, England) 2006;45(6):669-75.
2006: Ralf Lobmann; Thomas Pap; Andreas Ambrosch; Katrin Waldmann; Wolfgang König; Hendrik Lehnert
Differential effects of PDGF-BB on matrix metalloproteases and cytokine release in fibroblasts of Type 2 diabetic patients and normal controls in vitro.
Journal of diabetes and its complications 2006;20(2):105-12.
2005: Thomas Pap; Ingmar Meinecke; Ulf Müller-Ladner; Steffen Gay
Are fibroblasts involved in joint destruction?
Annals of the rheumatic diseases 2005;64 Suppl 4():iv52-4.
2005: Thomas Pap
Cyclophilins in rheumatoid arthritis--stepping into an undiscovered country?
Clinical immunology (Orlando, Fla.) 2005;116(3):199-201.
2005: Edita Rutkauskaite; Dagmar Volkmer; Yukio Shigeyama; Jörg Schedel; Géza Pap; Ulf Müller-Ladner; Ingmar Meinecke; Dorothea Alexander; Renate E Gay; Susanne Drynda; Wolfram Neumann; Beat A Michel; Wilhelm K Aicher; Steffen Gay; Thomas Pap
Retroviral gene transfer of an antisense construct against membrane type 1 matrix metalloproteinase reduces the invasiveness of rheumatoid arthritis synovial fibroblasts.
Arthritis and rheumatism 2005;52(7):2010-4.
2005: Andreas Drynda; Paul H A Quax; Manfred Neumann; Willemijn H van der Laan; Géza Pap; Susanne Drynda; Ingmar Meinecke; Jörn Kekow; Wolfram Neumann; Tom W J Huizinga; Michael Naumann; Wolfgang König; Thomas Pap
Gene transfer of tissue inhibitor of metalloproteinases-3 reverses the inhibitory effects of TNF-alpha on Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(10):6524-31.
2005: Lars-Henrik Meyer; Thomas Pap
MAPK signalling in rheumatoid joint destruction: can we unravel the puzzle?
Arthritis research & therapy 2005;7(5):177-8.
2005: Frank Bühling; Aline Wille; Christoph Röcken; Olaf Wiesner; Anja Baier; Ingmar Meinecke; Tobias Welte; Thomas Pap
Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis.
Respiratory research 2005;6():37.
2005: Ingmar Meinecke; Edita Rutkauskaite; Steffen Gay; Thomas Pap
The role of synovial fibroblasts in mediating joint destruction in rheumatoid arthritis.
Current pharmaceutical design 2005;11(5):563-8.
2005: Thomas Pap
Direct interaction of immunoglobulins with synovial fibroblasts: a missing link in the pathogenesis of rheumatoid arthritis?
Arthritis research & therapy 2005;7(1):44-6.
2004: Caroline Ospelt; Diego Kyburz; Matthias Pierer; Reinhart Seibl; M Kurowska; Oliver Distler; Michel Neidhart; U Muller-Ladner; Thomas Pap; Renate E Gay; Steffen Gay
Toll-like receptors in rheumatoid arthritis joint destruction mediated by two distinct pathways.
Annals of the rheumatic diseases 2004;63 Suppl 2():ii90-ii91.
2004: Lars C Huber; Thomas Pap; Ulf Müller-Ladner; Renate E Gay; Steffen Gay
Gene targeting: roadmap to future therapies.
Current rheumatology reports 2004;6(5):323-5.
2004: Thomas Pap; Michael Nawrath; Jochen Heinrich; Magnus Bosse; Anja Baier; Klaus M Hummel; Peter Petrow; Stefan Kuchen; Beat A Michel; Renate E Gay; Ulf Müller-Ladner; Karin Moelling; Steffen Gay
Cooperation of Ras- and c-Myc-dependent pathways in regulating the growth and invasiveness of synovial fibroblasts in rheumatoid arthritis.
Arthritis and rheumatism 2004;50(9):2794-802.
2004: Jörg Schedel; Christian A Seemayer; Thomas Pap; Michel Neidhart; Stefan Kuchen; Beat A Michel; Renate E Gay; Ulf Müller-Ladner; Steffen Gay; W Zacharias
Targeting cathepsin L (CL) by specific ribozymes decreases CL protein synthesis and cartilage destruction in rheumatoid arthritis.
Gene therapy 2004;11(13):1040-7.
2004: Edita Rutkauskaite; Wolfgang Zacharias; Jörg Schedel; Ulf Müller-Ladner; Christian Mawrin; Christian A Seemayer; Dorothea Alexander; Renate E Gay; Wilhelm K Aicher; Beat A Michel; Steffen Gay; Thomas Pap
Ribozymes that inhibit the production of matrix metalloproteinase 1 reduce the invasiveness of rheumatoid arthritis synovial fibroblasts.
Arthritis and rheumatism 2004;50(5):1448-56.
2004: Michaela Weis-Klemm; Dorothea Alexander; Thomas Pap; Heike Schützle; Dorothee Reyer; Juliane K Franz; Wilhelm K Aicher
Synovial fibroblasts from rheumatoid arthritis patients differ in their regulation of IL-16 gene activity in comparison to osteoarthritis fibroblasts.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2004;14(4-6):293-300.
2004: Michael George; B Stein; O Müller; Michaela Weis-Klemm; Thomas Pap; Wolfgang J Parak; Wilhelm K Aicher
Metabolic activation stimulates acid secretion and expression of matrix degrading proteases in human osteoblasts.
Annals of the rheumatic diseases 2004;63(1):67-70.
2003: Thomas Pap; Antje Cinski; Anja Baier; Steffen Gay; Ingmar Meinecke
Modulation of pathways regulating both the invasiveness and apoptosis in rheumatoid arthritis synovial fibroblasts.
Joint, bone, spine : revue du rhumatisme 2003;70(6):477-9.
2003: Matthias Pierer; Ulf Müller-Ladner; Thomas Pap; Michel Neidhart; Renate E Gay; Steffen Gay
The SCID mouse model: novel therapeutic targets - lessons from gene transfer.
Springer seminars in immunopathology 2003;25(1):65-78.
2003: Anja Baier; Ingmar Meineckel; Steffen Gay; Thomas Pap
Apoptosis in rheumatoid arthritis.
Current opinion in rheumatology 2003;15(3):274-9.
2003: Willemijn H van der Laan; Paul H A Quax; Christian A Seemayer; L G M Huisman; Elsbet Pieterman; Jos M Grimbergen; Jan H Verheijen; Ferdinand C Breedveld; Renate E Gay; Steffen Gay; Tom W J Huizinga; Thomas Pap
Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3.
Gene therapy 2003;10(3):234-42.
2003: Christian Mawrin; Thomas Pap; Merce Pallas; Knut Dietzmann; Wolfgang Behrens-Baumann; Christian K Vorwerk
Changes of retinal glutamate transporter GLT-1 mRNA levels following optic nerve damage.
Molecular vision 2003;9():10-3.
2003: Andreas Machner; Anja Baier; Aline Wille; Susanne Drynda; Géza Pap; Andreas Drynda; Christian Mawrin; Frank Bühling; Steffen Gay; Wolfram Neumann; Thomas Pap
Higher susceptibility to Fas ligand induced apoptosis and altered modulation of cell death by tumor necrosis factor-alpha in periarticular tenocytes from patients with knee joint osteoarthritis.
Arthritis research & therapy 2003;5(5):R253-61.
2003: Thomas Pap; Anja Claus; Susumu Ohtsu; Klaus M Hummel; Peter Schwartz; Susanne Drynda; Géza Pap; Andreas Machner; Bernhard Stein; Michael George; Renate E Gay; Wolfram Neumann; Steffen Gay; Wilhelm K Aicher
Osteoclast-independent bone resorption by fibroblast-like cells.
Arthritis research & therapy 2003;5(3):R163-73.
2003: Thomas Pap
New insights into integrin signalling: implications for rheumatoid arthritis synovial fibroblasts.
Arthritis research & therapy 2003;5(3):154-5.
2002: Jörn Kekow; Tobias Welte; Udo Kellner; Thomas Pap
Development of rheumatoid nodules during anti-tumor necrosis factor alpha therapy with etanercept.
Arthritis and rheumatism 2002;46(3):843-4.
2002: Thomas Pap; Renate E Gay; Ulf Müller-Ladner; Steffen Gay
Ex vivo gene transfer in the years to come.
Arthritis research 2002;4(1):10-2.
2001: Oliver Distler; Thomas Pap; Otylia Kowal-Bielecka; Rotraud Meyringer; Serena Guiducci; M Landthaler; Jürgen Schölmerich; Beat A Michel; Renate E Gay; Marco Matucci-Cerinic; Steffen Gay; Ulf Müller-Ladner
Overexpression of monocyte chemoattractant protein 1 in systemic sclerosis: role of platelet-derived growth factor and effects on monocyte chemotaxis and collagen synthesis.
Arthritis and rheumatism 2001;44(11):2665-78.
2001: Otylia Kowal-Bielecka; Oliver Distler; Michel Neidhart; P Künzler; Janine Rethage; Michael Nawrath; A Carossino; Thomas Pap; Ulf Müller-Ladner; Beat A Michel; Stanislaw Sierakowski; Marco Matucci-Cerinic; Renate E Gay; Steffen Gay
Evidence of 5-lipoxygenase overexpression in the skin of patients with systemic sclerosis: a newly identified pathway to skin inflammation in systemic sclerosis.
Arthritis and rheumatism 2001;44(8):1865-75.
2001: Géza Pap; Andreas Machner; T Rinnert; D Hörler; Renate E Gay; Helmut Schwarzberg; Wolfram Neumann; Beat A Michel; Steffen Gay; Thomas Pap
Development and characteristics of a synovial-like interface membrane around cemented tibial hemiarthroplasties in a novel rat model of aseptic prosthesis loosening.
Arthritis and rheumatism 2001;44(4):956-63.
2001: Thomas Pap; KR Aupperle; Steffen Gay; Gary S Firestein; Renate E Gay
Invasiveness of synovial fibroblasts is regulated by p53 in the SCID mouse in vivo model of cartilage invasion.
Arthritis and rheumatism 2001;44(3):676-81.
2001: Oliver Distler; Christian A Seemayer; Thomas Pap; Renate E Gay; Michel Neidhart; Ulf Müller-Ladner; Steffen Gay
Gene transfer of protective cytokines in rheumatoid arthritis.
Advances in experimental medicine and biology 2001;495():231-40.
2000: Thomas Pap; Willemijn H van der Laan; KR Aupperle; Renate E Gay; Jan H Verheijen; Gary S Firestein; Steffen Gay; Michel Neidhart
Modulation of fibroblast-mediated cartilage degradation by articular chondrocytes in rheumatoid arthritis.
Arthritis and rheumatism 2000;43(11):2531-6.
2000: Yukio Shigeyama; Thomas Pap; P Kunzler; B R Simmen; Renate E Gay; Steffen Gay
Expression of osteoclast differentiation factor in rheumatoid arthritis.
Arthritis and rheumatism 2000;43(11):2523-30.
2000: Haiko Sprott; Thomas Pap; Janine Rethage; W Wintersberger; Renate E Gay; LA Bradley; Daniel Uebelhart; Steffen Gay
Expression of the precursor of secretoneurin, secretogranin II, in the synovium of patients with rheumatoid arthritis and osteoarthritis.
The Journal of rheumatology 2000;27(10):2347-50.
2000: Willemijn H van der Laan; Thomas Pap; H Karel Ronday; Jos M Grimbergen; L G M Huisman; Johan teKoppele; Ferdinand C Breedveld; Renate E Gay; Steffen Gay; Tom W J Huizinga; Jan H Verheijen; Paul H A Quax
Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of a cell surface-targeted plasmin inhibitor.
Arthritis and rheumatism 2000;43(8):1710-8.
2000: Thomas Pap; Yukio Shigeyama; Stefan Kuchen; J K Fernihough; B Simmen; Renate E Gay; Michael E J Billingham; Steffen Gay
Differential expression pattern of membrane-type matrix metalloproteinases in rheumatoid arthritis.
Arthritis and rheumatism 2000;43(6):1226-32.
2000: Thomas Pap; Renate E Gay; Steffen Gay
Gene transfer: from concept to therapy.
Current opinion in rheumatology 2000;12(3):205-10.
2000: Juliane K Franz; Thomas Pap; Klaus M Hummel; Michael Nawrath; Wilhelm K Aicher; Yukio Shigeyama; Ulf Müller-Ladner; Renate E Gay; Steffen Gay
Expression of sentrin, a novel antiapoptotic molecule, at sites of synovial invasion in rheumatoid arthritis.
Arthritis and rheumatism 2000;43(3):599-607.
2000: Thomas Pap; Juliane K Franz; Klaus M Hummel; E Jeisy; Renate E Gay; Steffen Gay
Activation of synovial fibroblasts in rheumatoid arthritis: lack of Expression of the tumour suppressor PTEN at sites of invasive growth and destruction.
Arthritis research 2000;2(1):59-64.
2000: C Guincamp; Thomas Pap; Jörg Schedel; Géza Pap; U Moller-Ladner; Renate E Gay; Steffen Gay
Gene therapy in osteoarthritis.
Joint, bone, spine : revue du rhumatisme 2000;67(6):570-1.
2000: Thomas Pap; U Müller-Ladner; Renate E Gay; Steffen Gay
Fibroblast biology. Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis.
Arthritis research 2000;2(5):361-7.
2000: Andreas Machner; Thomas Pap; Helmut Schwarzberg; Hans-Wolfram Neumann; Géza Pap
[Joint loading as a possible etiology for arthrosis development. Results of animal experiment studies of the rat model].
Zentralblatt für Chirurgie 2000;125(6):536-42.
2000: Jörn Kekow; Thomas Pap; S Zielinski
Multifunctional role of proteases in rheumatic diseases.
Advances in experimental medicine and biology 2000;477():467-76.
1999: C S Westhoff; D Freudiger; Peter Petrow; C Seyfert; Josef Zacher; Jörg Kriegsmann; Thomas Pap; Steffen Gay; Peter Stiehl; Erika Gromnica-Ihle; Dirk Wernicke
Characterization of collagenase 3 (matrix metalloproteinase 13) messenger RNA expression in the synovial membrane and synovial fibroblasts of patients with rheumatoid arthritis.
Arthritis and rheumatism 1999;42(7):1517-27.
1999: Steffen Gay; Ulf Müller-Ladner; Klaus M Hummel; Thomas Pap; Renate E Gay
Anticytokines.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1999;7(3):317-8.
1999: Thomas Pap; U Müller-Ladner; Renate E Gay; Steffen Gay
Gene therapy in rheumatoid arthritis: how to target joint destruction?
Arthritis research 1999;1(1):5-9.
1999: Thomas Pap; Géza Pap; Klaus M Hummel; Juliane K Franz; E Jeisy; I Sainsbury; Renate E Gay; Michael E J Billingham; Wolfram Neumann; Steffen Gay
Membrane-type-1 matrix metalloproteinase is abundantly expressed in fibroblasts and osteoclasts at the bone-implant interface of aseptically loosened joint arthroplasties in situ.
The Journal of rheumatology 1999;26(1):166-9.
1998: Thomas Pap; Renate E Gay; Steffen Gay
Do antivirals have any utility in the treatment of arthritis?
Expert opinion on investigational drugs 1998;7(11):1841-8.
1998: Juliane K Franz; SA Kolb; Klaus M Hummel; F Lahrtz; Michel Neidhart; Wilhelm K Aicher; Thomas Pap; Renate E Gay; Adriano Fontana; Steffen Gay
Interleukin-16, produced by synovial fibroblasts, mediates chemoattraction for CD4+ T lymphocytes in rheumatoid arthritis.
European journal of immunology 1998;28(9):2661-71.