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Vassilios Papadopoulos
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20
Boujrad, Noureddine
19
Culty, Martine
17
Lecanu, Laurent
16
Li, Hua
15
Drieu, Katy
15
Yao, Zhi-Xing
13
Amri, Hakima
13
Greeson, Janet
12
Han, Zeqiu
11
Dym, Martin
10
Vidic, B
9
Carreau, Serge
8
Zirkin, Barry
7
Li, Wenping
7
Lacapère, Jean-Jacques
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All Publications
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2010: Batarseh Amani; Papadopoulos Vassilios
Regulation of translocator protein 18 kDa (TSPO) expression in health and disease states.
Molecular and cellular endocrinology 2010;327(1-2):1-12.
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2010: Ostuni Mariano A; Issop Leeyah; Péranzi Gabriel; Walker Francine; Fasseu Magali; Elbim Carole; Papadopoulos Vassilios; Lacapere Jean-Jacques
Overexpression of translocator protein in inflammatory bowel disease: Potential diagnostic and treatment value.
Inflammatory bowel diseases 2010;16(9):1476-87.
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2010: Fan Jinjiang; Traore Kassim; Li Wenping; Amri Hakima; Huang Hongzhan; Wu Cathy; Chen Haolin; Zirkin Barry; Papadopoulos Vassilios
Molecular mechanisms mediating the effect of mono-(2-ethylhexyl) phthalate on hormone-stimulated steroidogenesis in MA-10 mouse tumor Leydig cells.
Endocrinology 2010;151(7):3348-62.
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2010: Martinez-Arguelles Daniel B; Papadopoulos Vassilios
Epigenetic regulation of the expression of genes involved in steroid hormone biosynthesis and action.
Steroids 2010;75(7):467-76.
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2010: Fan Jinjiang; Liu Jun; Culty Martine; Papadopoulos Vassilios
Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): an emerging signaling molecule.
Progress in lipid research 2010;49(3):218-34.
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2010: Batarseh Amani; Li Jiehan; Papadopoulos Vassilios
Protein kinase C epsilon regulation of translocator protein (18 kDa) Tspo gene expression is mediated through a MAPK pathway targeting STAT3 and c-Jun transcription factors.
Biochemistry 2010;49(23):4766-78.
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2010: Lecanu L; Rammouz G; McCourty A; Sidahmed E K; Greeson J; Papadopoulos V
Caprospinol reduces amyloid deposits and improves cognitive function in a rat model of Alzheimer's disease.
Neuroscience 2010;165(2):427-35.
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2009: Martinez-Arguelles D B; Culty M; Zirkin B R; Papadopoulos V
In utero exposure to di-(2-ethylhexyl) phthalate decreases mineralocorticoid receptor expression in the adult testis.
Endocrinology 2009;150(12):5575-85.
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2009: Fan Jinjiang; Rone Malena B; Papadopoulos Vassilios
Translocator protein 2 is involved in cholesterol redistribution during erythropoiesis.
The Journal of biological chemistry 2009;284(44):30484-97.
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2009: Ostuni Mariano Anibal; Péranzi Gabriel; Ducroc Robert A; Fasseu Magali; Vidic Branislav; Dumont Janice; Papadopoulos Vassilios; Lacapere Jean-Jacques
Distribution, pharmacological characterization and function of the 18 kDa translocator protein in rat small intestine.
Biology of the cell / under the auspices of the European Cell Biology Organization 2009;101(10):573-86.
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2009: Papadopoulos Vassilios; Lecanu Laurent
Translocator protein (18 kDa) TSPO: an emerging therapeutic target in neurotrauma.
Experimental neurology 2009;219(1):53-7.
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2009: Rone Malena B; Liu Jun; Blonder Josip; Ye Xiaoying; Veenstra Timothy D; Young Jason C; Papadopoulos Vassilios
Targeting and insertion of the cholesterol-binding translocator protein into the outer mitochondrial membrane.
Biochemistry 2009;48(29):6909-20.
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2009: Liu Ying; Pocivavsek Ana; Papadopoulos Vassilios
Dehydroepiandrosterone formation is independent of cytochrome P450 17alpha-hydroxylase/17, 20 lyase activity in the mouse brain.
The Journal of steroid biochemistry and molecular biology 2009;115(3-5):86-90.
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2009: Favreau Frederic; Rossard Ludivine; Zhang Keqiang; Desurmont Thibault; Manguy Emilie; Belliard Aude; Fabre Stéphane; Liu Jun; Han Zeqiu; Thuillier Raphael; Papadopoulos Vassilios; Hauet Thierry
Expression and modulation of translocator protein and its partners by hypoxia reoxygenation or ischemia and reperfusion in porcine renal models.
American journal of physiology. Renal physiology 2009;297(1):F177-90.
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2009: Rone Malena B; Fan Jinjiang; Papadopoulos Vassilios
Cholesterol transport in steroid biosynthesis: role of protein-protein interactions and implications in disease states.
Biochimica et biophysica acta 2009;1791(7):646-58.
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2009: Lecanu Laurent; Tillement Laurent; Rammouz Georges; Tillement Jean Paul; Greeson Janet; Papadopoulos Vassilios
Caprospinol: moving from a neuroactive steroid to a neurotropic drug.
Expert opinion on investigational drugs 2009;18(3):265-76.
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2009: Midzak Andrew S; Chen Haolin; Papadopoulos Vassilios; Zirkin Barry R
Leydig cell aging and the mechanisms of reduced testosterone synthesis.
Molecular and cellular endocrinology 2009;299(1):23-31.
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2009: Xu Jing; Lecanu Laurent; Tan Matthew; Greeson Janet; Papadopoulos Vassilios
Identification of a benzamide derivative that inhibits stress-induced adrenal corticosteroid synthesis.
Molecules (Basel, Switzerland) 2009;14(9):3392-410.
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2008: Batarseh Amani; Giatzakis Christoforos; Papadopoulos Vassilios
Phorbol-12-myristate 13-acetate acting through protein kinase Cepsilon induces translocator protein (18-kDa) TSPO gene expression.
Biochemistry 2008;47(48):12886-99.
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2008: Doucet Carole; Milin Serge; Favreau Frederic; Desurmont Thibault; Manguy Emilie; Hébrard William; Yamamoto Yuriyo; Mauco Gérard; Eugene Michel; Papadopoulos Vassilios; Hauet Thierry; Goujon Jean Michel
A p38 mitogen-activated protein kinase inhibitor protects against renal damage in a non-heart-beating donor model.
American journal of physiology. Renal physiology 2008;295(1):F179-91.
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2008: Ostuni Mariano A; Tumilasci Omar R; Péranzi Gabriel; Cardoso Estela M L; Contreras Liliana N; Arregger Alejandro L; Papadopoulos Vassilios; Lacapere Jean-Jacques
Effect of translocator protein (18 kDa)-ligand binding on neurotransmitter-induced salivary secretion in rat submandibular glands.
Biology of the cell / under the auspices of the European Cell Biology Organization 2008;100(7):427-39.
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2008: Murail Samuel; Robert Jean-Claude; Coïc Yves-Marie; Neumann Jean-Michel; Ostuni Mariano A; Yao Zhin-Xing; Papadopoulos Vassilios; Jamin Nadège; Lacapère Jean-Jacques
Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding.
Biochimica et biophysica acta 2008;1778(6):1375-81.
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2008: Culty Martine; Thuillier Raphael; Li Wenping; Wang Yan; Martinez-Arguelles Daniel B; Benjamin Carolina Gesteira; Triantafilou Kostantinos M; Zirkin Barry R; Papadopoulos Vassilios
In utero exposure to di-(2-ethylhexyl) phthalate exerts both short-term and long-lasting suppressive effects on testosterone production in the rat.
Biology of reproduction 2008;78(6):1018-28.
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2008: Rosenberg Brian G; Chen Haolin; Folmer Janet; Liu June; Papadopoulos Vassilios; Zirkin Barry R
Gestational exposure to atrazine: effects on the postnatal development of male offspring.
Journal of andrology 2008;29(3):304-11.
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2007: Ostuni Mariano A; Ducroc Robert; Péranzi Gabriel; Tonon Marie-Christine; Papadopoulos Vassilios; Lacapere Jean-Jacques
Translocator protein (18 kDa) ligand PK 11195 induces transient mitochondrial Ca2+ release leading to transepithelial Cl- secretion in HT-29 human colon cancer cells.
Biology of the cell / under the auspices of the European Cell Biology Organization 2007;99(11):639-47.
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2007: Yao Z-X; Han Z; Xu J; Greeson J; Lecanu L; Papadopoulos V
22R-Hydroxycholesterol induces differentiation of human NT2 precursor (Ntera2/D1 teratocarcinoma) cells.
Neuroscience 2007;148(2):441-53.
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2007: Lecanu Laurent; Papadopoulos Vassilios
Cutting-edge patents in Alzheimer's disease drug discovery: anticipation of potential future treatments.
Recent patents on CNS drug discovery 2007;2(2):113-23.
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2007: Liu Ying; Dettin Luis E; Folmer Janet; Zirkin Barry R; Papadopoulos Vassilios
Abnormal morphology of spermatozoa in cytochrome P450 17alpha-hydroxylase/17, 20-lyase (CYP17) deficient mice.
Journal of andrology 2007;28(3):453-60.
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2007: Giatzakis Christoforos; Batarseh Amani; Dettin Luis; Papadopoulos Vassilios
The role of Ets transcription factors in the basal transcription of the translocator protein (18 kDa).
Biochemistry 2007;46(16):4763-74.
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2007: Papadopoulos Vassilios; Liu Jun; Culty Martine
Is there a mitochondrial signaling complex facilitating cholesterol import?
Molecular and cellular endocrinology 2007;265-266():59-64.
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2007: Li Wenping; Hardwick Matthew J; Rosenthal Dean; Culty Martine; Papadopoulos Vassilios
Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation.
Biochemical pharmacology 2007;73(4):491-503.
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2006: Liu Jun; Rone Malena B; Papadopoulos Vassilios
Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis.
The Journal of biological chemistry 2006;281(50):38879-93.
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2006: Akula Nagaraju; Lecanu Laurent; Greeson Janet; Papadopoulos Vassilios
3D QSAR studies of AChE inhibitors based on molecular docking scores and CoMFA.
Bioorganic & medicinal chemistry letters 2006;16(24):6277-80.
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2006: Papadopoulos Vassilios; Baraldi Mario; Guilarte Tomás R; Knudsen Thomas B; Lacapère Jean-Jacques; Lindemann Peter; Norenberg Michael D; Nutt David; Weizman Abraham; Zhang Ming-Rong; Gavish Moshe
Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function.
Trends in pharmacological sciences 2006;27(8):402-9.
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2006: Tillement Laurent; Lecanu Laurent; Yao Wenguo; Greeson Janet; Papadopoulos Vassilios
The spirostenol (22R, 25R)-20alpha-spirost-5-en-3beta-yl hexanoate blocks mitochondrial uptake of Abeta in neuronal cells and prevents Abeta-induced impairment of mitochondrial function.
Steroids 2006;71(8):725-35.
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2006: Pretner Ewald; Amri Hakima; Li Wenping; Brown Rachel; Lin Chin-Shoou; Makariou Erini; Defeudis Francis V; Drieu Katy; Papadopoulos Vassilios
Cancer-related overexpression of the peripheral-type benzodiazepine receptor and cytostatic anticancer effects of Ginkgo biloba extract (EGb 761).
Anticancer research 2006;26(1A):9-22.
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2006: Xu Jing; Lecanu Laurent; Tan Matthew; Yao Wenguo; Greeson Janet; Papadopoulos Vassilios
The benzamide derivative N-[1-(7-tert-Butyl-1H-indol-3-ylmethyl)-2-(4-cyclopropanecarbonyl-3-methyl-piperazin-1-yl)-2-oxo-ethyl]-4-nitro-benzamide (SP-10) reduces HIV-1 infectivity in vitro by modifying actin dynamics.
Antiviral chemistry & chemotherapy 2006;17(6):331-42.
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2006: Papadopoulos V; Lecanu L; Brown R C; Han Z; Yao Z-X
Peripheral-type benzodiazepine receptor in neurosteroid biosynthesis, neuropathology and neurological disorders.
Neuroscience 2006;138(3):749-56.
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2006: Lecanu Laurent; Greeson Janet; Papadopoulos Vassilios
Beta-amyloid and oxidative stress jointly induce neuronal death, amyloid deposits, gliosis, and memory impairment in the rat brain.
Pharmacology 2006;76(1):19-33.
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2005: Teper Gary L; Lecanu Laurent; Greeson Janet; Papadopoulos Vassilios
Methodology for multi-site ligand-protein docking identification developed for the optimization of spirostenol inhibition of beta-amyloid-induced neurotoxicity.
Chemistry & biodiversity 2005;2(11):1571-9.
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2005: Liu Ying; Yao Zhi-Xing; Bendavid Claude; Borgmeyer Carol; Han Zeqiu; Cavalli Luciane R; Chan Wai-Yee; Folmer Janet; Zirkin Barry R; Haddad Bassem R; Gallicano G Ian; Papadopoulos Vassilios
Haploinsufficiency of cytochrome P450 17alpha-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice.
Molecular endocrinology (Baltimore, Md.) 2005;19(9):2380-9.
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2005: Lecanu Laurent; Yao Wenguo; Piechot Alexander; Greeson Janet; Tzalis Dimitrios; Papadopoulos Vassilios
Identification, design, synthesis, and pharmacological activity of (4-ethyl-piperazin-1-yl)-phenylmethanone derivatives with neuroprotective properties against beta-amyloid-induced toxicity.
Neuropharmacology 2005;49(1):86-96.
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2005: Liu Ying; Yao Zhi-Xing; Papadopoulos Vassilios
Cytochrome P450 17alpha hydroxylase/17,20 lyase (CYP17) function in cholesterol biosynthesis: identification of squalene monooxygenase (epoxidase) activity associated with CYP17 in Leydig cells.
Molecular endocrinology (Baltimore, Md.) 2005;19(7):1918-31.
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2005: Papadopoulos Vassilios
Cholesterol homeostasis and infertility: the liver X receptor connection.
Endocrinology 2005;146(6):2517-8.
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2005: Lecanu Laurent; Wenguo Yao; Xu Jing; Greeson Janet; Papadopoulos Vassilios
Local anesthetic procaine protects rat pheochromocytoma PC12 cells against beta-amyloid-induced neurotoxicity.
Pharmacology 2005;74(2):65-78.
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2005: Jamin Nadège; Neumann Jean-Michel; Ostuni Mariano A; Vu Thi Kim Ngoc; Yao Zhi-Xing; Murail Samuel; Robert Jean-Claude; Giatzakis Christoforos; Papadopoulos Vassilios; Lacapère Jean-Jacques
Characterization of the cholesterol recognition amino acid consensus sequence of the peripheral-type benzodiazepine receptor.
Molecular endocrinology (Baltimore, Md.) 2005;19(3):588-94.
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2005: Hauet Thierry; Yao Zhi-Xing; Bose Himangshu S; Wall Christopher T; Han Zeqiu; Li Wenping; Hales Dale B; Miller Walter L; Culty Martine; Papadopoulos Vassilios
Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria.
Molecular endocrinology (Baltimore, Md.) 2005;19(2):540-54.
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2004: Yao Zhi-Xing; Han Zeqiu; Drieu Katy; Papadopoulos Vassilios
Ginkgo biloba extract (Egb 761) inhibits beta-amyloid production by lowering free cholesterol levels.
The Journal of nutritional biochemistry 2004;15(12):749-56.
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2004: Papadopoulos V
In search of the function of the peripheral-type benzodiazepine receptor.
Endocrine research 2004;30(4):677-84.
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2004: Li Wenping; Amri Hakima; Huang Hongzhan; Wu Cathy; Papadopoulos Vassilios
Gene and protein profiling of the response of MA-10 Leydig tumor cells to human chorionic gonadotropin.
Journal of andrology 2004;25(6):900-13.
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2004: Ostuni M A; Marazova K; Peranzi G; Vidic B; Papadopoulos V; Ducroc R; Lacapere J-J
Functional characterization and expression of PBR in rat gastric mucosa: stimulation of chloride secretion by PBR ligands.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(6):G1069-80.
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2004: Lee J J; Eisenberg P; Papadopoulos V; Wang J; Widmaier E P
Reversible changes in adrenocorticotropin (ACTH)-induced adrenocortical steroidogenesis and expression of the peripheral-type benzodiazepine receptor during the ACTH-insensitive period in young rats.
Endocrinology 2004;145(5):2165-73.
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2004: Amri Hakima; Li Wenping; Drieu Katy; Papadopoulos Vassilios
Identification of the adrenocorticotropin and ginkgolide B-regulated 90-kilodalton protein (p90) in adrenocortical cells as a serotransferrin precursor protein homolog (adrenotransferrin).
Endocrinology 2004;145(4):1802-9.
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2004: Giatzakis Christoforos; Papadopoulos Vassilios
Differential utilization of the promoter of peripheral-type benzodiazepine receptor by steroidogenic versus nonsteroidogenic cell lines and the role of Sp1 and Sp3 in the regulation of basal activity.
Endocrinology 2004;145(3):1113-23.
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2004: Lecanu Laurent; Yao Wenguo; Teper Gary L; Yao Zhi-Xing; Greeson Janet; Papadopoulos Vassilios
Identification of naturally occurring spirostenols preventing beta-amyloid-induced neurotoxicity.
Steroids 2004;69(1):1-16.
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2004: Diallo S; Lecanu L; Greeson J; Papadopoulos V
A capillary gas chromatography/mass spectrometric method for the quantification of hydroxysteroids in human plasma.
Analytical biochemistry 2004;324(1):123-30.
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2003: Xu Jing; Lecanu Laurent; Han Zeqiu; Yao Zhixing; Greeson Janet; Papadopoulos Vassilios
Inhibition of adrenal cortical steroid formation by procaine is mediated by reduction of the cAMP-induced 3-hydroxy-3-methylglutaryl-coenzyme A reductase messenger ribonucleic acid levels.
The Journal of pharmacology and experimental therapeutics 2003;307(3):1148-57.
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2003: Wendler Gregor; Lindemann Peter; Lacapère Jean-Jacques; Papadopoulos Vassilios
Protoporphyrin IX binding and transport by recombinant mouse PBR.
Biochemical and biophysical research communications 2003;311(4):847-52.
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2003: Lacapère Jean Jacques; Papadopoulos Vassilios
Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis.
Steroids 2003;68(7-8):569-85.
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2003: Li Wenping; Trovero Fabrice; Cordier Jocelyne; Wang Yan; Drieu Katy; Papadopoulos Vassilios
Prenatal exposure of rats to Ginkgo biloba extract (EGb 761) increases neuronal survival/growth and alters gene expression in the developing fetal hippocampus.
Brain research. Developmental brain research 2003;144(2):169-80.
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2003: DeFeudis Francis V; Papadopoulos Vassilios; Drieu Katy
Ginkgo biloba extracts and cancer: a research area in its infancy.
Fundamental & clinical pharmacology 2003;17(4):405-17.
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2003: Liu Jun; Li Hua; Papadopoulos Vassilios
PAP7, a PBR/PKA-RIalpha-associated protein: a new element in the relay of the hormonal induction of steroidogenesis.
The Journal of steroid biochemistry and molecular biology 2003;85(2-5):275-83.
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2003: Liu Jun; Matyakhina Ludmila; Han Zeqiu; Sandrini Fabiano; Bei Thalia; Stratakis Constantine A; Papadopoulos Vassilios
Molecular cloning, chromosomal localization of human peripheral-type benzodiazepine receptor and PKA regulatory subunit type 1A (PRKAR1A)-associated protein PAP7, and studies in PRKAR1A mutant cells and tissues.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):1189-91.
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2003: Liu Jun; Cavalli Luciane R; Haddad Bassem R; Papadopoulos Vassilios
Molecular cloning, genomic organization, chromosomal mapping and subcellular localization of mouse PAP7: a PBR and PKA-RIalpha associated protein.
Gene 2003;308():1-10.
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2003: Delavoie Franck; Li Hua; Hardwick Matthew; Robert Jean-Claude; Giatzakis Christoforos; Péranzi Gabriel; Yao Zhi-Xing; Maccario Jean; Lacapère Jean-Jacques; Papadopoulos Vassilios
In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding.
Biochemistry 2003;42(15):4506-19.
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2003: Amri Hakima; Drieu Katy; Papadopoulos Vassilios
Transcriptional suppression of the adrenal cortical peripheral-type benzodiazepine receptor gene and inhibition of steroid synthesis by ginkgolide B.
Biochemical pharmacology 2003;65(5):717-29.
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2003: Brown Rachel C; Han Zeqiu; Cascio Caterina; Papadopoulos Vassilios
Oxidative stress-mediated DHEA formation in Alzheimer's disease pathology.
Neurobiology of aging 2003;24(1):57-65.
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2003: Han Zeqiu; Slack Rebecca S; Li Wenping; Papadopoulos Vassilios
Expression of peripheral benzodiazepine receptor (PBR) in human tumors: relationship to breast, colorectal, and prostate tumor progression.
Journal of receptor and signal transduction research 2003;23(2-3):225-38.
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2002: Yao Zhi-Xing; Brown Rachel C; Teper Gary; Greeson Janet; Papadopoulos Vassilios
22R-Hydroxycholesterol protects neuronal cells from beta-amyloid-induced cytotoxicity by binding to beta-amyloid peptide.
Journal of neurochemistry 2002;83(5):1110-9.
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2002: Hardwick Matthew; Cavalli Luciane R; Barlow Keith D; Haddad Bassem R; Papadopoulos Vassilios
Peripheral-type benzodiazepine receptor (PBR) gene amplification in MDA-MB-231 aggressive breast cancer cells.
Cancer genetics and cytogenetics 2002;139(1):48-51.
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2002: Hauet T; Liu J; Li H; Gazouli M; Culty M; Papadopoulos V
PBR, StAR, and PKA: partners in cholesterol transport in steroidogenic cells.
Endocrine research 2002;28(4):395-401.
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2002: Gazouli Maria; Han Zeqiu; Papadopoulos Vassilios
Identification of a peptide antagonist to the peripheral-type benzodiazepine receptor that inhibits hormone-stimulated leydig cell steroid formation.
The Journal of pharmacology and experimental therapeutics 2002;303(2):627-32.
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2002: Yao Zhi-Xing; Papadopoulos Vassilios
Function of beta-amyloid in cholesterol transport: a lead to neurotoxicity.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(12):1677-9.
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2002: Li Wenping; Pretner Ewald; Shen Liya; Drieu Katy; Papadopoulos Vassilios
Common gene targets of Ginkgo biloba extract (EGb 761) in human tumor cells: relation to cell growth.
Cellular and molecular biology (Noisy-le-Grand, France) 2002;48(6):655-62.
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2002: Amri Hakima; Drieu Katy; Papadopoulos Vassilios
Use of ginkgolide B and a ginkgolide-activated response element to control gene transcription: example of the adrenocortical peripheral-type benzodiazepine receptor.
Cellular and molecular biology (Noisy-le-Grand, France) 2002;48(6):633-9.
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2002: Gazouli Maria; Yao Zhi-Xing; Boujrad Noureddine; Corton J Christopher; Culty Martine; Papadopoulos Vassilios
Effect of peroxisome proliferators on Leydig cell peripheral-type benzodiazepine receptor gene expression, hormone-stimulated cholesterol transport, and steroidogenesis: role of the peroxisome proliferator-activator receptor alpha.
Endocrinology 2002;143(7):2571-83.
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2002: Culty Martine; Luo Lindi; Yao Zhi-Xing; Chen Haolin; Papadopoulos Vassilios; Zirkin Barry R
Cholesterol transport, peripheral benzodiazepine receptor, and steroidogenesis in aging Leydig cells.
Journal of andrology 2002;23(3):439-47.
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2001: Li H; Degenhardt B; Tobin D; Yao Z X; Tasken K; Papadopoulos V
Identification, localization, and function in steroidogenesis of PAP7: a peripheral-type benzodiazepine receptor- and PKA (RIalpha)-associated protein.
Molecular endocrinology (Baltimore, Md.) 2001;15(12):2211-28.
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2001: Hardwick M; Rone J; Han Z; Haddad B; Papadopoulos V
Peripheral-type benzodiazepine receptor levels correlate with the ability of human breast cancer MDA-MB-231 cell line to grow in SCID mice.
International journal of cancer. Journal international du cancer 2001;94(3):322-7.
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2001: Papadopoulos V; Amri H; Li H; Yao Z; Brown R C; Vidic B; Culty M
Structure, function and regulation of the mitochondrial peripheral-type benzodiazepine receptor.
Thérapie 2001;56(5):549-56.
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2001: Lacapère J J; Delavoie F; Li H; Péranzi G; Maccario J; Papadopoulos V; Vidic B
Structural and functional study of reconstituted peripheral benzodiazepine receptor.
Biochemical and biophysical research communications 2001;284(2):536-41.
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2001: Dees J H; Gazouli M; Papadopoulos V
Effect of mono-ethylhexyl phthalate on MA-10 Leydig tumor cells.
Reproductive toxicology (Elmsford, N.Y.) 2001;15(2):171-87.
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2001: Yao Z; Drieu K; Papadopoulos V
The Ginkgo biloba extract EGb 761 rescues the PC12 neuronal cells from beta-amyloid-induced cell death by inhibiting the formation of beta-amyloid-derived diffusible neurotoxic ligands.
Brain research 2001;889(1-2):181-90.
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2001: Li H; Yao Z; Degenhardt B; Teper G; Papadopoulos V
Cholesterol binding at the cholesterol recognition/ interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):1267-72.
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2001: Brown R C; Papadopoulos V
Role of the peripheral-type benzodiazepine receptor in adrenal and brain steroidogenesis.
International review of neurobiology 2001;46():117-43.
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2000: Cascio C; Brown R C; Liu Y; Han Z; Hales D B; Papadopoulos V
Pathways of dehydroepiandrosterone formation in rat brain glia.
The Journal of steroid biochemistry and molecular biology 2000;75(2-3):177-86.
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2000: Papadopoulos V; Kapsis A; Li H; Amri H; Hardwick M; Culty M; Kasprzyk P G; Carlson M; Moreau J P; Drieu K
Drug-induced inhibition of the peripheral-type benzodiazepine receptor expression and cell proliferation in human breast cancer cells.
Anticancer research 2000;20(5A):2835-47.
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2000: Boujrad N; Vidic B; Gazouli M; Culty M; Papadopoulos V
The peroxisome proliferator perfluorodecanoic acid inhibits the peripheral-type benzodiazepine receptor (PBR) expression and hormone-stimulated mitochondrial cholesterol transport and steroid formation in Leydig cells.
Endocrinology 2000;141(9):3137-48.
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2000: Brown R C; Cascio C; Papadopoulos V
Pathways of neurosteroid biosynthesis in cell lines from human brain: regulation of dehydroepiandrosterone formation by oxidative stress and beta-amyloid peptide.
Journal of neurochemistry 2000;74(2):847-59.
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1999: Yao Z X; Drieu K; Szweda L I; Papadopoulos V
Free radicals and lipid peroxidation do not mediate beta-amyloid-induced neuronal cell death.
Brain research 1999;847(2):203-10.
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1999: Papadopoulos V; Dharmarajan A M; Li H; Culty M; Lemay M; Sridaran R
Mitochondrial peripheral-type benzodiazepine receptor expression. Correlation with gonadotropin-releasing hormone (GnRH) agonist-induced apoptosis in the corpus luteum.
Biochemical pharmacology 1999;58(9):1389-93.
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1999: Culty M; Li H; Boujrad N; Amri H; Vidic B; Bernassau J M; Reversat J L; Papadopoulos V
In vitro studies on the role of the peripheral-type benzodiazepine receptor in steroidogenesis.
The Journal of steroid biochemistry and molecular biology 1999;69(1-6):123-30.
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1999: Hardwick M; Fertikh D; Culty M; Li H; Vidic B; Papadopoulos V
Peripheral-type benzodiazepine receptor (PBR) in human breast cancer: correlation of breast cancer cell aggressive phenotype with PBR expression, nuclear localization, and PBR-mediated cell proliferation and nuclear transport of cholesterol.
Cancer research 1999;59(4):831-42.
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1999: Zilz A; Li H; Castello R; Papadopoulos V; Widmaier E P
Developmental expression of the peripheral-type benzodiazepine receptor and the advent of steroidogenesis in rat adrenal glands.
Endocrinology 1999;140(2):859-64.
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1999: Sridaran R; Philip G H; Li H; Culty M; Liu Z; Stocco D M; Papadopoulos V
GnRH agonist treatment decreases progesterone synthesis, luteal peripheral benzodiazepine receptor mRNA, ligand binding and steroidogenic acute regulatory protein expression during pregnancy.
Journal of molecular endocrinology 1999;22(1):45-54.
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1998: Li H; Papadopoulos V
Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern.
Endocrinology 1998;139(12):4991-7.
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1998: Papadopoulos V; Widmaier E P; Amri H; Zilz A; Li H; Culty M; Castello R; Philip G H; Sridaran R; Drieu K
In vivo studies on the role of the peripheral benzodiazepine receptor (PBR) in steroidogenesis.
Endocrine research 1998;24(3-4):479-87.
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1998: Cascio C; Prasad V V; Lin Y Y; Lieberman S; Papadopoulos V
Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):2862-7.
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1997: Papadopoulos V; Amri H; Li H; Boujrad N; Vidic B; Garnier M
Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell line.
The Journal of biological chemistry 1997;272(51):32129-35.
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1997: Amri H; Drieu K; Papadopoulos V
Ex vivo regulation of adrenal cortical cell steroid and protein synthesis, in response to adrenocorticotropic hormone stimulation, by the Ginkgo biloba extract EGb 761 and isolated ginkgolide B.
Endocrinology 1997;138(12):5415-26.
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1997: Kozikowski A P; Kotoula M; Ma D; Boujrad N; Tückmantel W; Papadopoulos V
Synthesis and biology of a 7-nitro-2,1,3-benzoxadiazol-4-yl derivative of 2-phenylindole-3-acetamide: a fluorescent probe for the peripheral-type benzodiazepine receptor.
Journal of medicinal chemistry 1997;40(16):2435-9.
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1997: Vidic B; Boujrad N; Papadopoulos V
Acute action of choriogonadotropin on Leydig tumor cells: qualitative and quantitative transformation of lipid moieties.
The Anatomical record 1997;248(3):374-9.
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1997: Li H; Papadopoulos V; Vidic B; Dym M; Culty M
Regulation of rat testis gonocyte proliferation by platelet-derived growth factor and estradiol: identification of signaling mechanisms involved.
Endocrinology 1997;138(3):1289-98.
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1997: Papadopoulos V; Amri H; Boujrad N; Cascio C; Culty M; Garnier M; Hardwick M; Li H; Vidic B; Brown A S; Reversa J L; Bernassau J M; Drieu K
Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis.
Steroids 1997;62(1):21-8.
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1996: Boujrad N; Vidic B; Papadopoulos V
Acute action of choriogonadotropin on Leydig tumor cells: changes in the topography of the mitochondrial peripheral-type benzodiazepine receptor.
Endocrinology 1996;137(12):5727-30.
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1996: Amri H; Ogwuegbu S O; Boujrad N; Drieu K; Papadopoulos V
In vivo regulation of peripheral-type benzodiazepine receptor and glucocorticoid synthesis by Ginkgo biloba extract EGb 761 and isolated ginkgolides.
Endocrinology 1996;137(12):5707-18.
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1996: Jia M C; Ravindranath N; Papadopoulos V; Dym M
Regulation of c-fos mRNA expression in Sertoli cells by cyclic AMP, calcium, and protein kinase C mediated pathways.
Molecular and cellular biochemistry 1996;156(1):43-9.
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1996: Ravindranath N; Papadopoulos V; Brooker G; Dym M
Rat Sertoli cell calcium response to basement membrane and follicle-stimulating hormone.
Biology of reproduction 1996;54(1):130-7.
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1995: Boujrad N; Ogwuegbu S O; Garnier M; Lee C H; Martin B M; Papadopoulos V
Identification of a stimulator of steroid hormone synthesis isolated from testis.
Science (New York, N.Y.) 1995;268(5217):1609-12.
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1995: Papadopoulos V; Brown A S
Role of the peripheral-type benzodiazepine receptor and the polypeptide diazepam binding inhibitor in steroidogenesis.
The Journal of steroid biochemistry and molecular biology 1995;53(1-6):103-10.
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1995: Guarneri P; Guarneri R; Cascio C; Piccoli F; Papadopoulos V
gamma-Aminobutyric acid type A/benzodiazepine receptors regulate rat retina neurosteroidogenesis.
Brain research 1995;683(1):65-72.
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1994: Boujrad N; Gaillard J L; Garnier M; Papadopoulos V
Acute action of choriogonadotropin on Leydig tumor cells: induction of a higher affinity benzodiazepine-binding site related to steroid biosynthesis.
Endocrinology 1994;135(4):1576-83.
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1994: Garnier M; Boujrad N; Ogwuegbu S O; Hudson J R; Papadopoulos V
The polypeptide diazepam-binding inhibitor and a higher affinity mitochondrial peripheral-type benzodiazepine receptor sustain constitutive steroidogenesis in the R2C Leydig tumor cell line.
The Journal of biological chemistry 1994;269(35):22105-12.
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1994: Papadopoulos V; Boujrad N; Ikonomovic M D; Ferrara P; Vidic B
Topography of the Leydig cell mitochondrial peripheral-type benzodiazepine receptor.
Molecular and cellular endocrinology 1994;104(1):R5-9.
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1994: Papadopoulos V; Dym M
Sertoli cell differentiation on basement membrane is mediated by the c-fos protooncogene.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):7027-31.
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1994: Ravindranath N; Papadopoulos V; Vornberger W; Zitzmann D; Dym M
Ultrastructural distribution of calcium in the rat testis.
Biology of reproduction 1994;51(1):50-62.
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1994: Guarneri P; Guarneri R; Cascio C; Pavasant P; Piccoli F; Papadopoulos V
Neurosteroidogenesis in rat retinas.
Journal of neurochemistry 1994;63(1):86-96.
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1994: Whalin M E; Boujrad N; Papadopoulos V; Krueger K E
Studies on the phosphorylation of the 18 kDa mitochondrial benzodiazepine receptor protein.
Journal of receptor research 1994;14(3-4):217-28.
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1994: Garnier M; Dimchev A B; Boujrad N; Price J M; Musto N A; Papadopoulos V
In vitro reconstitution of a functional peripheral-type benzodiazepine receptor from mouse Leydig tumor cells.
Molecular pharmacology 1994;45(2):201-11.
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1994: Papadopoulos V; Guarneri P
Regulation of C6 glioma cell steroidogenesis by adenosine 3',5'-cyclic monophosphate.
Glia 1994;10(1):75-8.
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1993: Papadopoulos V; Jia M C; Culty M; Hall P F; Dym M
Rat Sertoli cell aromatase cytochrome P450: regulation by cell culture conditions and relationship to the state of cell differentiation.
In vitro cellular & developmental biology. Animal 1993;29A(12):943-9.
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1993: Lamsam-Casalotti S; Onoda M; Papadopoulos V; Dym M
Developmental expression of GTP-binding proteins in rat testes.
Journal of reproduction and fertility 1993;99(2):487-95.
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1993: Boujrad N; Hudson J R; Papadopoulos V
Inhibition of hormone-stimulated steroidogenesis in cultured Leydig tumor cells by a cholesterol-linked phosphorothioate oligodeoxynucleotide antisense to diazepam-binding inhibitor.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5728-31.
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1993: Papadopoulos V
Peripheral-type benzodiazepine/diazepam binding inhibitor receptor: biological role in steroidogenic cell function.
Endocrine reviews 1993;14(2):222-40.
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1993: Garnier M; Boujrad N; Oke B O; Brown A S; Riond J; Ferrara P; Shoyab M; Suarez-Quian C A; Papadopoulos V
Diazepam binding inhibitor is a paracrine/autocrine regulator of Leydig cell proliferation and steroidogenesis: action via peripheral-type benzodiazepine receptor and independent mechanisms.
Endocrinology 1993;132(1):444-58.
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1992: Radhakrishnan B; Oke B O; Papadopoulos V; DiAugustine R P; Suarez-Quian C A
Characterization of epidermal growth factor in mouse testis.
Endocrinology 1992;131(6):3091-9.
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1992: Oke B O; Suarez-Quian C A; Riond J; Ferrara P; Papadopoulos V
Cell surface localization of the peripheral-type benzodiazepine receptor (PBR) in adrenal cortex.
Molecular and cellular endocrinology 1992;87(1-3):R1-6.
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1992: Romeo E; Auta J; Kozikowski A P; Ma D; Papadopoulos V; Puia G; Costa E; Guidotti A
2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR).
The Journal of pharmacology and experimental therapeutics 1992;262(3):971-8.
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1992: Dym M; Papadopoulos V
Dual compartment (bicameral) culture: role of basement membrane in epithelial differentiation.
Cell biology and toxicology 1992;8(3):55-9.
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1992: Guarneri P; Papadopoulos V; Pan B; Costa E
Regulation of pregnenolone synthesis in C6-2B glioma cells by 4'-chlorodiazepam.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):5118-22.
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1992: Papadopoulos V; Guarneri P; Kreuger K E; Guidotti A; Costa E
Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):5113-7.
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1991: Papadopoulos V; Berkovich A; Krueger K E
The role of diazepam binding inhibitor and its processing products at mitochondrial benzodiazepine receptors: regulation of steroid biosynthesis.
Neuropharmacology 1991;30(12B):1417-23.
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1991: Papadopoulos V; Berkovich A; Krueger K E; Costa E; Guidotti A
Diazepam binding inhibitor and its processing products stimulate mitochondrial steroid biosynthesis via an interaction with mitochondrial benzodiazepine receptors.
Endocrinology 1991;129(3):1481-8.
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1991: Kamtchouing P; Hochereau de Reviers M T; Perreau C; Papadopoulos V; Drosdowsky M A; Carreau S
Age-related changes in the function of the pituitary-gonadal axis in a sterile male rat mutant (hd/hd).
Biology of reproduction 1991;45(1):11-9.
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1991: Papadopoulos V
Identification and purification of a human Sertoli cell-secreted protein (hSCSP-80) stimulating Leydig cell steroid biosynthesis.
The Journal of clinical endocrinology and metabolism 1991;72(6):1332-9.
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1991: Onoda M; Djakiew D; Papadopoulos V
Pachytene spermatocytes regulate the secretion of Sertoli cell protein(s) which stimulate Leydig cell steroidogenesis.
Molecular and cellular endocrinology 1991;77(1-3):207-16.
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1991: Davis C M; Papadopoulos V; Jia M C; Yamada Y; Kleinman H K; Dym M
Identification and partial characterization of laminin binding proteins in immature rat Sertoli cells.
Experimental cell research 1991;193(2):262-73.
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1991: Papadopoulos V; Nowzari F B; Krueger K E
Hormone-stimulated steroidogenesis is coupled to mitochondrial benzodiazepine receptors. Tropic hormone action on steroid biosynthesis is inhibited by flunitrazepam.
The Journal of biological chemistry 1991;266(6):3682-7.
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1990: Davis C M; Papadopoulos V; Sommers C L; Kleinman H K; Dym M
Differential expression of extracellular matrix components in rat Sertoli cells.
Biology of reproduction 1990;43(5):860-9.
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1990: Ojeifo J O; Byers S W; Papadopoulos V; Dym M
Sertoli cell-secreted protein(s) stimulates DNA synthesis in purified rat Leydig cells in vitro.
Journal of reproduction and fertility 1990;90(1):93-108.
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1990: Krueger K E; Papadopoulos V
Peripheral-type benzodiazepine receptors mediate translocation of cholesterol from outer to inner mitochondrial membranes in adrenocortical cells.
The Journal of biological chemistry 1990;265(25):15015-22.
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1990: Papadopoulos V; Mukhin A G; Costa E; Krueger K E
The peripheral-type benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis.
The Journal of biological chemistry 1990;265(7):3772-9.
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1990: Boujrad N; Denis I; Papadopoulos V; Pisselet C; Bouchard P; Drosdowsky M A; Hochereau de Reviers M T; Carreau S
[Demonstration of LH inhibitor(s) in sheep and human sera]
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1990;310(9):417-21.
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1989: Mukhin A G; Papadopoulos V; Costa E; Krueger K E
Mitochondrial benzodiazepine receptors regulate steroid biosynthesis.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9813-6.
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1989: Boujrad N; Papadopoulos V; Drosdowsky M A; Carreau S
[Role of a purified Sertoli cell protein (CMB-21) in the biosynthesis of Leydig cell testosterone in the immature rat]
Pathologie-biologie 1989;37(7):819-23.
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1988: Kamtchouing P; Pinon-Lataillade G; Papadopoulos V; Drosdowsky M A; Hochereau de Reviers M T; Carreau S
Changes in androgen binding protein (ABP) production following continuous low dose gamma irradiation (IR) of adult rat.
Steroids 1988;52(4):349-50.
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1988: Kamtchouing P; Pinon-Lataillade G; Papadopoulos V; Guillaumin J M; Bardos P; Maas J; Perreau C; Drosdowsky M A; Hochereau de Reviers M T; Carreau S
Effect of continuous low-dose gamma-irradiation on rat Sertoli cell function.
Reproduction, nutrition, development 1988;28(4B):1009-17.
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1988: Carreau S; Papadopoulos V; Boujrad N; Drosdowsky M A
Effects of cisplatin and bleomycin on mature rat Leydig cell testosterone production.
Journal of steroid biochemistry 1988;30(1-6):449-51.
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1987: Papadopoulos V; Kamtchouing P; Drosdowsky M A; Hochereau de Reviers M T; Carreau S
Adult rat Sertoli cells secrete a factor or factors which modulate Leydig cell function.
The Journal of endocrinology 1987;114(3):459-67.
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1987: Papadopoulos V; Kamtchouing P; Drosdowsky M A; Carreau S
Spent media from immature seminiferous tubules and Sertoli cells inhibit adult rat Leydig cell aromatase activity.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1987;19(2):62-4.
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1987: Papadopoulos V; Kamtchouing P; Drosdowsky M A; Carreau S
Effects of the transmethylation inhibitor S-adenosyl-homocysteine and of the methyl donor S-adenosyl-methionine on rat Leydig cell function in vitro.
Journal of steroid biochemistry 1987;26(1):93-8.
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