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Klearchos Papas

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Kate R Mueller; A N Balamurugan; Gary W Cline; Melanie L Graham; Rebecca L Hooper; Jennifer P Kitzmann; Rebecca L Pongratz; Henk-Jan Schuurman; Michael J Taylor; Bradley P Weegman; Klearchos K Papas
Differences in glucose-stimulated insulin secretion in vitro of islets from human, nonhuman primate, and porcine origin.
Klearchos K Papas; Paris Pappas; François Pattou; Thierry Berney; Theodore Karatzas; Thomas Minor; James Shaw; Christian Toso; Henk-Jan Schuurman
International workshop: islet transplantation without borders enabling islet transplantation in Greece with international collaboration and innovative technology.
Thomas M Suszynski; David Er Sutherland; Linda A Tempelman; Michael D Rizzari; William E Scott; Nicolas Chronos; Peter M Eckman; James D Fonger; Ranjit John; Klearchos K Papas
Persufflation (gaseous oxygen perfusion) as a method of heart preservation.

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2013: Kate R Mueller; A N Balamurugan; Gary W Cline; Melanie L Graham; Rebecca L Hooper; Jennifer P Kitzmann; Rebecca L Pongratz; Henk-Jan Schuurman; Michael J Taylor; Bradley P Weegman; Klearchos K Papas
Differences in glucose-stimulated insulin secretion in vitro of islets from human, nonhuman primate, and porcine origin.
Xenotransplantation 2013;20(2):75-81.
2013: Klearchos K Papas; Paris Pappas; François Pattou; Thierry Berney; Theodore Karatzas; Thomas Minor; James Shaw; Christian Toso; Henk-Jan Schuurman
International workshop: islet transplantation without borders enabling islet transplantation in Greece with international collaboration and innovative technology.
Clinical transplantation 2013;27(2):E116-25.
2013: Thomas M Suszynski; David Er Sutherland; Linda A Tempelman; Michael D Rizzari; William E Scott; Nicolas Chronos; Peter M Eckman; James D Fonger; Ranjit John; Klearchos K Papas
Persufflation (gaseous oxygen perfusion) as a method of heart preservation.
Journal of cardiothoracic surgery 2013;8():105.
2012: Thomas Minor; Klearchos K Papas; Patrik Efferz; Bastian Luer; Michael D Rizzari; William E Scott; Thomas M Suszynski; Andreas Paul
Energetic recovery in porcine grafts by minimally invasive liver oxygenation.
The Journal of surgical research 2012;178(2):e59-63.
2012: Jennifer P Kitzmann; Lee Law; Kate R Mueller; Marija Muzina; Henk-Jan Schuurman; Avik Shome; Robert B Elliott; Klearchos K Papas
Real-time assessment of encapsulated neonatal porcine islets prior to clinical xenotransplantation.
Xenotransplantation 2012;19(6):333-6.
2012: Thomas M Suszynski; Michael J Taylor; Linda A Tempelman; Michael D Rizzari; William E Scott; Klearchos K Papas
Persufflation (or gaseous oxygen perfusion) as a method of organ preservation.
Cryobiology 2012;64(3):125-43.
2012: A N Balamurugan; Melena D Bellin; James Harmon; Takayuki Anazawa; Gopalakrishnan Loganathan; Robert McCarthy; Klearchos K Papas; David M Radosevich; Sajjad M Soltani; David E R Sutherland; Mukesh Tiwari; Joshua J Wilhelm; Takeshi Yuasa; Bernhard J Hering
A new enzyme mixture to increase the yield and transplant rate of autologous and allogeneic human islet products.
Transplantation 2012;93(7):693-702.
2012: Efstathios S Avgoustiniatos; A N Balamurugan; Daniel W Fraga; Andrew S Friberg; Bernhard J Hering; Connor A Lyons; Kate R Mueller; Rebecca A Nelson; Phillip R Rozak; Henk-Jan Schuurman; William E Scott; Thomas M Suszynski; David E R Sutherland; Tomohiro Tanaka; Gina M Wildey; Jeffrey D Ansite; Klearchos K Papas
Supplements in human islet culture: human serum albumin is inferior to fetal bovine serum.
Cell transplantation 2012;21(12):2805-14.
2011: Gary W Cline; Rebecca L Pongratz; Xiaojian Zhao; Klearchos K Papas
Rates of insulin secretion in INS-1 cells are enhanced by coupling to anaplerosis and Kreb's cycle flux independent of ATP synthesis.
Biochemical and biophysical research communications 2011;415(1):30-5.
2011: T M Suszynski; S A Stein; Efstathios S Avgoustiniatos; E J Falde; Bruce E Hammer; Klearchos K Papas
Assessment of tissue-engineered islet graft viability by fluorine magnetic resonance spectroscopy.
Transplantation proceedings 2011;43(9):3221-5.
2011: Janine Abouaish; Pratima Bansal-Pakala; Melanie Graham; Bernhard J Hering; Gopalakrishnan Loganathan; Robert C McCarthy; Klearchos K Papas; Sajjad M Soltani; David E R Sutherland; Mukesh Tiwari; Takeshi Yuasa; A N Balamurugan
Successful isolation and transplantation of nonhuman primate islets using a novel purified enzyme blend.
Transplantation 2011;92(8):e40-2.
2011: Venkata Sunil Kumar Sajja; Michael J Taylor; Helen Gapsis; Byron Guernsey; Thomas R Hanley; David J Kennedy; Klearchos K Papas; Paul W Todd
Application of magnetic particle tracking velocimetry to quadrupole magnetic sorting of porcine pancreatic islets.
Biotechnology and bioengineering 2011;108(9):2107-17.
2011: Thomas M Suszynski; Paul W Todd; Rebecca L Pongratz; Michael D Rizzari; Henk-Jan Schuurman; Efstathios S Avgoustiniatos; Christopher S Chapman; Gary W Cline; David J Kennedy; Louis S Kidder; Jennifer P Kitzmann; Kate Mueller; Timothy D O'Brien; Klearchos K Papas
Paramagnetic microparticles do not elicit islet cytotoxicity with co-culture or host immune reactivity after implantation.
Xenotransplantation 2011;18(4):239-44.
2011: Takayuki Anazawa; Shuichiro Matsumoto; Yukihide Yonekawa; Gopalakrishnan Loganathan; Joshua J Wilhelm; Sajjad M Soltani; Klearchos K Papas; David E R Sutherland; Bernhard J Hering; A N Balamurugan
Prediction of pancreatic tissue densities by an analytical test gradient system before purification maximizes human islet recovery for islet autotransplantation/allotransplantation.
Transplantation 2011;91(5):508-14.
2011: Juan E Abrahante; Kyra Martins; Klearchos K Papas; Bernhard J Hering; Henk-Jan Schuurman; Michael P Murtaugh
Microbiological safety of porcine islets: comparison with source pig.
Xenotransplantation 2011;18(2):88-93.
2011: Nicole Atchison; Wei Fan; Damien D Brewer; Manickam A Arunagirinathan; Bernhard J Hering; Satish Kumar; Klearchos K Papas; Efrosini Kokkoli; Michael Tsapatsis
Silica-nanoparticle coatings by adsorption from lysine-silica-nanoparticle Sols on inorganic and biological surfaces.
Angewandte Chemie (International ed. in English) 2011;50(7):1617-21.
2010: M D Rizzari; T M Suszynski; L S Kidder; S A Stein; T D O'Brien; V S K Sajja; W E Scott; V A Kirchner; B P Weegman; Efstathios S Avgoustiniatos; Paul W Todd; D J Kennedy; Bruce E Hammer; DE Sutherland; Bernhard J Hering; Klearchos K Papas
Surgical protocol involving the infusion of paramagnetic microparticles for preferential incorporation within porcine islets.
Transplantation proceedings 2010;42(10):4209-12.
2010: Anna Pisania; Klearchos K Papas; Daryl E Powers; Michael J Rappel; Abdulkadir Omer; Susan Bonner-Weir; Gordon C Weir; Clark K Colton
Enumeration of islets by nuclei counting and light microscopic analysis.
Laboratory investigation; a journal of technical methods and pathology 2010;90(11):1676-86.
2010: Nicole A Atchison; Wei Fan; Klearchos K Papas; Bernhard J Hering; Michael Tsapatsis; Efrosini Kokkoli
Binding of the fibronectin-mimetic peptide, PR_b, to alpha5beta1 on pig islet cells increases fibronectin production and facilitates internalization of PR_b functionalized liposomes.
Langmuir : the ACS journal of surfaces and colloids 2010;26(17):14081-8.
2010: T Anazawa; A N Balamurugan; Klearchos K Papas; Efstathios S Avgoustiniatos; J Ferrer; S Matsumoto; DE Sutherland; Bernhard J Hering
Improved method of porcine pancreas procurement with arterial flush and ductal injection enhances islet isolation outcome.
Transplantation proceedings 2010;42(6):2032-5.
2010: B P Weegman; V A Kirchner; W E Scott; Efstathios S Avgoustiniatos; T M Suszynski; J Ferrer-Fabrega; M D Rizzari; L S Kidder; Raja Kandaswamy; DE Sutherland; Klearchos K Papas
Continuous real-time viability assessment of kidneys based on oxygen consumption.
Transplantation proceedings 2010;42(6):2020-3.
2010: W E Scott; T D O'Brien; J Ferrer-Fabrega; Efstathios S Avgoustiniatos; B P Weegman; T Anazawa; S Matsumoto; V A Kirchner; M D Rizzari; Michael P Murtaugh; T M Suszynski; T Aasheim; L S Kidder; Bruce E Hammer; S G Stone; L A Tempelman; DE Sutherland; Bernhard J Hering; Klearchos K Papas
Persufflation improves pancreas preservation when compared with the two-layer method.
Transplantation proceedings 2010;42(6):2016-9.
2010: W E Scott; B P Weegman; J Ferrer-Fabrega; S A Stein; T Anazawa; V A Kirchner; M D Rizzari; J Stone; S Matsumoto; Bruce E Hammer; A N Balamurugan; L S Kidder; T M Suszynski; Efstathios S Avgoustiniatos; S G Stone; L A Tempelman; DE Sutherland; Bernhard J Hering; Klearchos K Papas
Pancreas oxygen persufflation increases ATP levels as shown by nuclear magnetic resonance.
Transplantation proceedings 2010;42(6):2011-5.
2010: A N Balamurugan; Andrew G Breite; Takayuki Anazawa; Gopalakrishnan Loganathan; Joshua J Wilhelm; Klearchos K Papas; Francis E Dwulet; Robert C McCarthy; Bernhard J Hering
Successful human islet isolation and transplantation indicating the importance of class 1 collagenase and collagen degradation activity assay.
Transplantation 2010;89(8):954-61.
2010: Klearchos K Papas; Clark K Colton; Andi Qipo; Haiyan Wu; Rebecca A Nelson; Bernhard J Hering; Gordon C Weir; Maria Koulmanda
Prediction of marginal mass required for successful islet transplantation.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2010;23(1):28-34.
2009: Klearchos K Papas; Thomas M Suszynski; Clark K Colton
Islet assessment for transplantation.
Current opinion in organ transplantation 2009;14(6):674-82.
2009: T Anazawa; A N Balamurugan; M Bellin; Hui-Jian Zhang; S Matsumoto; Y Yonekawa; T Tanaka; G Loganathan; Klearchos K Papas; Gregory Beilman; Bernhard J Hering; DE Sutherland
Human islet isolation for autologous transplantation: comparison of yield and function using SERVA/Nordmark versus Roche enzymes.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(10):2383-91.
2009: Rustin M Shenkman; Jeffrey J Chalmers; Bernhard J Hering; Nicole Kirchhof; Klearchos K Papas
Quadrupole magnetic sorting of porcine islets of Langerhans.
Tissue engineering. Part C, Methods 2009;15(2):147-56.
2009: Rustin M Shenkman; Ruben Godoy-Silva; Klearchos K Papas; Jeffrey J Chalmers
Effects of energy dissipation rate on islets of Langerhans: implications for isolation and transplantation.
Biotechnology and bioengineering 2009;103(2):413-23.
2008: M D Bellin; Raja Kandaswamy; J Parkey; Hui-Jian Zhang; B Liu; S H Ihm; Jeffrey D Ansite; J Witson; Pratima Bansal-Pakala; A N Balamurugan; K K Papas; Klearchos K Papas; DE Sutherland; Antoinette Moran; Bernhard J Hering
Prolonged insulin independence after islet allotransplants in recipients with type 1 diabetes.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(11):2463-70.
2008: Yasuhiro Iwanaga; David E R Sutherland; James V Harmon; Klearchos K Papas
Pancreas preservation for pancreas and islet transplantation.
Current opinion in organ transplantation 2008;13(2):135-41.
2008: P R Rozak; B P Weegman; Efstathios S Avgoustiniatos; John Wilson; D P Welch; Bernhard J Hering; Klearchos K Papas
Devices and methods for maintenance of temperature and pressure during islet shipment.
Transplantation proceedings 2008;40(2):407-10.
2008: W E Scott; S Matsumoto; T Tanaka; Efstathios S Avgoustiniatos; M L Graham; P C Williams; L A Tempelman; David E R Sutherland; Bernhard J Hering; B E Hammer; Klearchos K Papas
Real-time noninvasive assessment of pancreatic ATP levels during cold preservation.
Transplantation proceedings 2008;40(2):403-6.
2008: Efstathios S Avgoustiniatos; Bernhard J Hering; P R Rozak; John Wilson; L A Tempelman; A N Balamurugan; D P Welch; B P Weegman; T M Suszynski; Klearchos K Papas
Commercially available gas-permeable cell culture bags may not prevent anoxia in cultured or shipped islets.
Transplantation proceedings 2008;40(2):395-400.
2008: T M Suszynski; G M Wildey; E J Falde; G W Cline; K Stewart Maynard; N Ko; J Sotiris; A Naji; Bernhard J Hering; Klearchos K Papas
The ATP/DNA ratio is a better indicator of islet cell viability than the ADP/ATP ratio.
Transplantation proceedings 2008;40(2):346-50.
2007: Klearchos K Papas; Anna Pisania; Haiyan Wu; Gordon C Weir; Clark K Colton
A stirred microchamber for oxygen consumption rate measurements with pancreatic islets.
Biotechnology and bioengineering 2007;98(5):1071-82.
2007: C M T Dvorak; Maria Hårdstedt; H Xie; M Wang; Klearchos K Papas; B J Hering; Michael P Murtaugh; SC Fahrenkrug
Transcriptional profiling of stress response in cultured porcine islets.
Biochemical and biophysical research communications 2007;357(1):118-25.
2007: Klearchos K Papas; Clark K Colton; R A Nelson; P R Rozak; Efstathios S Avgoustiniatos; W E Scott; G M Wildey; Anna Pisania; Gordon C Weir; Bernhard J Hering
Human islet oxygen consumption rate and DNA measurements predict diabetes reversal in nude mice.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(3):707-13.
2006: Efstathios S Avgoustiniatos; Bernhard J Hering; Klearchos K Papas
The rat pancreas is not an appropriate model for testing the preservation of the human pancreas with the two-layer method.
Transplantation 2006;81(10):1471-2; author reply 1472.
2005: Klearchos K Papas; Bernhard J Hering; L Guenther; L Gunther; M J Rappel; Clark K Colton; Efstathios S Avgoustiniatos
Pancreas oxygenation is limited during preservation with the two-layer method.
Transplantation proceedings 2005;37(8):3501-4.
2005: Klearchos K Papas; Efstathios S Avgoustiniatos; L A Tempelman; Gordon C Weir; Clark K Colton; Anna Pisania; M J Rappel; A S Friberg; A C Bauer; Bernhard J Hering
High-density culture of human islets on top of silicone rubber membranes.
Transplantation proceedings 2005;37(8):3412-4.
2004: Gary W Cline; Rebecca L Lepine; Klearchos K Papas; Richard G Kibbey; Gerald I Shulman
13C NMR isotopomer analysis of anaplerotic pathways in INS-1 cells.
The Journal of biological chemistry 2004;279(43):44370-5.
2001: Klearchos K Papas; Clark K Colton; John S Gounarides; Eric S Roos; M A Jarema; michael shapiro; L L Cheng; G W Cline; G I Shulman; Haiyan Wu; S Bonner-Weir; Gordon C Weir
NMR spectroscopy in beta cell engineering and islet transplantation.
Annals of the New York Academy of Sciences 2001;944():96-119.
1999: Klearchos K Papas; L Sun; Eric S Roos; John S Gounarides; michael shapiro; C M Nalin
Change in lactate production in Myc-transformed cells precedes apoptosis and can be inhibited by Bcl-2 overexpression.
FEBS letters 1999;446(2-3):338-42.
1998: Klearchos K Papas; M A Jarema
Glucose-stimulated insulin secretion is not obligatorily linked to an increase in O2 consumption in betaHC9 cells.
The American journal of physiology 1998;275(6 Pt 1):E1100-6.