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Dmitri Papkovsky

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Alexander V Zhdanov; Ruslan I Dmitriev; Svetlana A Gavrilova; Anna V Golubeva; Dmitri B Papkovsky
Chronic hypoxia leads to a glycolytic phenotype and suppressed HIF-2 signaling in PC12 cells.
Danielle M Troppens; Ruslan I Dmitriev; Fergal O'Gara; Dmitri B Papkovsky; John P Morrissey
Genome-wide investigation of cellular targets and mode of action of the antifungal bacterial metabolite 2,4-diacetylphloroglucinol in Saccharomyces cerevisiae.
G Jasionek; Vladimir I Ogurtsov; Dmitri B Papkovsky
Rapid detection and respirometric profiling of aerobic bacteria on panels of selective media.

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All Publications

2013: Alexander V Zhdanov; Ruslan I Dmitriev; Svetlana A Gavrilova; Anna V Golubeva; Dmitri B Papkovsky
Chronic hypoxia leads to a glycolytic phenotype and suppressed HIF-2 signaling in PC12 cells.
Biochimica et biophysica acta 2013;1830(6):3553-69.
2013: Danielle M Troppens; Ruslan I Dmitriev; Fergal O'Gara; Dmitri B Papkovsky; John P Morrissey
Genome-wide investigation of cellular targets and mode of action of the antifungal bacterial metabolite 2,4-diacetylphloroglucinol in Saccharomyces cerevisiae.
FEMS yeast research 2013;13(3):322-34.
2013: G Jasionek; Vladimir I Ogurtsov; Dmitri B Papkovsky
Rapid detection and respirometric profiling of aerobic bacteria on panels of selective media.
Journal of applied microbiology 2013;114(2):423-32.
2012: Alexander V Zhdanov; Ruslan I Dmitriev; Dmitri B Papkovsky
Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling.
Bioscience reports 2012;32(6):587-95.
2012: Tatiana D Papkovskaia; Dmitri B Papkovsky; Anthony H V Schapira; James Staddon; Michael R Duchen; John Hardy; Daniel G Healy; Francisco Inesta-Vaquera; Koji Nishio; Kai-Yin Chau; J Mark Cooper
G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization.
Human molecular genetics 2012;21(19):4201-13.
2012: Ruslan I Dmitriev; Dmitri B Papkovsky
Optical probes and techniques for O2 measurement in live cells and tissue.
Cellular and molecular life sciences : CMLS 2012;69(12):2025-39.
2012: Klaus Koren; Dmitri B Papkovsky; Sergey M Borisov; Ruslan I Dmitriev; Ingo Klimant
Complexes of Ir(III)-octaethylporphyrin with peptides as probes for sensing cellular O2.
Chembiochem : a European journal of chemical biology 2012;13(8):1184-90.
2012: Ruslan I Dmitriev; Grzegorz Jasionek; Alexander V Zhdanov; Dmitri B Papkovsky
Assessment of cellular oxygen gradients with a panel of phosphorescent oxygen-sensitive probes.
Analytical chemistry 2012;84(6):2930-8.
2011: A V Zhdanov; Patrick J Pollard; J Adam; C Favre; R O'Connor; L O'Flaherty; Dmitri B Papkovsky
Comparative bioenergetic assessment of transformed cells using a cell energy budget platform.
Integrative biology : quantitative biosciences from nano to macro 2011;3(11):1135-42.
2011: Andreas Fercher; Ingo Klimant; Sergey M Borisov; Alexander V Zhdanov; Dmitri B Papkovsky
Intracellular O2 sensing probe based on cell-penetrating phosphorescent nanoparticles.
ACS nano 2011;5(7):5499-508.
2011: A Hempel; N Borchert; H Walsh; K Roy Choudhury; J P Kerry; Dmitri B Papkovsky
Analysis of total aerobic viable counts in raw fish by high-throughput optical oxygen respirometry.
Journal of food protection 2011;74(5):776-82.
2011: Alexander V Zhdanov; Ruslan I Dmitriev; Dmitri B Papkovsky
Bafilomycin A1 activates respiration of neuronal cells via uncoupling associated with flickering depolarization of mitochondria.
Cellular and molecular life sciences : CMLS 2011;68(5):903-17.
2011: Christian Frezza; Barbara A Hedley; Gabriela Kalna; Dmitri B Papkovsky; Daniel A Tennant; David G Watson; Liang Zheng; Eyal Gottlieb
Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival.
PloS one 2011;6(9):e24411.
2011: Nicolas B Borchert; Gelii V Ponomarev; Joe P Kerry; Dmitri B Papkovsky
O(2)/pH multisensor based on one phosphorescent dye.
Analytical chemistry 2011;83(1):18-22.
2010: Ruslan I Dmitriev; Honorata M Ropiak; Dmitri V Yashunsky; Gelii V Ponomarev; Alexander V Zhdanov; Dmitri B Papkovsky
Bactenecin 7 peptide fragment as a tool for intracellular delivery of a phosphorescent oxygen sensor.
The FEBS journal 2010;277(22):4651-61.
2010: Alexander V Zhdanov; Vladimir I Ogurtsov; Cormac T Taylor; Dmitri B Papkovsky
Monitoring of cell oxygenation and responses to metabolic stimulation by intracellular oxygen sensing technique.
Integrative biology : quantitative biosciences from nano to macro 2010;2(9):443-51.
2010: Alexander V Zhdanov; Manus W Ward; Cormac T Taylor; Ekaterina A Souslova; Dmitri M Chudakov; Jochen H M Prehn; Dmitri B Papkovsky
Extracellular calcium depletion transiently elevates oxygen consumption in neurosecretory PC12 cells through activation of mitochondrial Na+/Ca2+ exchange.
Biochimica et biophysica acta 2010;1797(9):1627-37.
2010: C Favre; A Zhdanov; M Leahy; Dmitri B Papkovsky; Rosemary O'Connor
Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells.
Oncogene 2010;29(27):3964-76.
2010: Grzegorz Jasionek; Alexander Zhdanov; John Davenport; Ludek Bláha; Dmitri B Papkovsky
Mitochondrial toxicity of microcystin-LR on cultured cells: application to the analysis of contaminated water samples.
Environmental science & technology 2010;44(7):2535-41.
2010: Andreas Fercher; Gelii V Ponomarev; Dmitri Yashunski; Dmitri B Papkovsky
Evaluation of the derivates of phosphorescent Pt-coproporphyrin as intracellular oxygen-sensitive probes.
Analytical and bioanalytical chemistry 2010;396(5):1793-803.
2010: Ruslan I Dmitriev; Alexander V Zhdanov; Gelii V Ponomarev; Dmitri V Yashunski; Dmitri B Papkovsky
Intracellular oxygen-sensitive phosphorescent probes based on cell-penetrating peptides.
Analytical biochemistry 2010;398(1):24-33.
2010: Alice Zitova; James Hynes; Julien Kollar; Sergey M Borisov; Ingo Klimant; Dmitri B Papkovsky
Analysis of activity and inhibition of oxygen-dependent enzymes by optical respirometry on the LightCycler system.
Analytical biochemistry 2010;397(2):144-51.
2010: Ross N Gillanders; Olga V Arzhakova; Andreas Hempel; Alla Dolgova; Joe P Kerry; Larisa M Yarysheva; Nikolai F Bakeev; Alexander L Volynskii; Dmitri B Papkovsky
Phosphorescent oxygen sensors based on nanostructured polyolefin substrates.
Analytical chemistry 2010;82(2):466-8.
2010: Andreas Fercher; Tomás C O'Riordan; Alexander V Zhdanov; Ruslan I Dmitriev; Dmitri B Papkovsky
Imaging of cellular oxygen and analysis of metabolic responses of mammalian cells.
Methods in molecular biology (Clifton, N.J.) 2010;591():257-73.
2009: James Hynes; Tomás C O'Riordan; Alexander V Zhdanov; Georg Uray; Yvonne Will; Dmitri B Papkovsky
In vitro analysis of cell metabolism using a long-decay pH-sensitive lanthanide probe and extracellular acidification assay.
Analytical biochemistry 2009;390(1):21-8.
2009: Katherine Schouest; Alice Zitova; Charles Spillane; Dmitri B Papkovsky
Toxicological assessment of chemicals using Caenorhabditis elegans and optical oxygen respirometry.
Environmental toxicology and chemistry / SETAC 2009;28(4):791-9.
2009: Alice Zitova; Fiach C O'Mahony; Maud Cross; John Davenport; Dmitri B Papkovsky
Toxicological profiling of chemical and environmental samples using panels of test organisms and optical oxygen respirometry.
Environmental toxicology 2009;24(2):116-27.
2009: Kathleen A O'Hagan; Sinead Cocchiglia; Alexander V Zhdanov; Murtaza Tambuwala; Murtaza M Tambawala; Eoin P Cummins; Mona Monfared; Terence A Agbor; John F Garvey; Dmitri B Papkovsky; Cormac T Taylor; Bernard B Allan
PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(7):2188-93.
2008: Alexander V Zhdanov; Manus W Ward; Jochen H M Prehn; Dmitri B Papkovsky
Dynamics of intracellular oxygen in PC12 Cells upon stimulation of neurotransmission.
The Journal of biological chemistry 2008;283(9):5650-61.
2007: Tomás C O'Riordan; Alexander V Zhdanov; Gelii V Ponomarev; Dmitri B Papkovsky
Analysis of intracellular oxygen and metabolic responses of mammalian cells by time-resolved fluorometry.
Analytical chemistry 2007;79(24):9414-9.
2007: Tomás C O'Riordan; Kathleen Fitzgerald; Gelii V Ponomarev; John Mackrill; James Hynes; Cormac Taylor; Dmitri B Papkovsky
Sensing intracellular oxygen using near-infrared phosphorescent probes and live-cell fluorescence imaging.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;292(4):R1613-20.
2007: Martina Burke; Paul J O'Sullivan; Gelii V Ponomarev; D V Yashunsky; Dmitri B Papkovsky
Analysis of close proximity quenching of phosphorescent metalloporphyrin labels in oligonucleotide structures.
Analytica chimica acta 2007;585(1):139-46.
2007: Desmond J O'Shea; Tomás C O'Riordan; Paul J O'Sullivan; Dmitri B Papkovsky
Homogeneous time-resolved fluorescence assays for the detection of activity and inhibition of phosphatase enzymes employing phosphorescently labeled peptide substrates.
Analytica chimica acta 2007;583(2):349-56.
2006: Ciara O'Donovan; Eoin Twomey; John Alderman; Tom Moore; Dmitri B Papkovsky
Development of a respirometric biochip for embryo assessment.
Lab on a chip 2006;6(11):1438-44.
2006: James Hynes; Roger Hill; Dmitri B Papkovsky
The use of a fluorescence-based oxygen uptake assay in the analysis of cytotoxicity.
Toxicology in vitro : an international journal published in association with BIBRA 2006;20(5):785-92.
2006: James Hynes; Lisa D Marroquin; Vladimir I Ogurtsov; Katerina N Christiansen; Gregory J Stevens; Dmitri B Papkovsky; Yvonne Will
Investigation of drug-induced mitochondrial toxicity using fluorescence-based oxygen-sensitive probes.
Toxicological sciences : an official journal of the Society of Toxicology 2006;92(1):186-200.
2006: Dmitri B Papkovsky; James Hynes; Yvonne Will
Respirometric Screening Technology for ADME-Tox studies.
Expert opinion on drug metabolism & toxicology 2006;2(2):313-23.
2006: Fiach C O'Mahony; Dmitri B Papkovsky
Rapid high-throughput assessment of aerobic bacteria in complex samples by fluorescence-based oxygen respirometry.
Applied and environmental microbiology 2006;72(2):1279-87.
2006: Yvonne Will; James Hynes; Vladimir I Ogurtsov; Dmitri B Papkovsky
Analysis of mitochondrial function using phosphorescent oxygen-sensitive probes.
Nature protocols 2006;1(6):2563-72.
2005: James Hynes; Tomás C O'Riordan; James Curtin; Thomas G Cotter; Dmitri B Papkovsky
Fluorescence based oxygen uptake analysis in the study of metabolic responses to apoptosis induction.
Journal of immunological methods 2005;306(1-2):193-201.
2005: Dmitri B Papkovsky; Tomás C O'Riordan
Emerging applications of phosphorescent metalloporphyrins.
Journal of fluorescence 2005;15(4):569-84.
2005: Fiach C O'Mahony; Ciara O'Donovan; James Hynes; Tom Moore; John Davenport; Dmitri B Papkovsky
Optical oxygen microrespirometry as a platform for environmental toxicology and animal model studies.
Environmental science & technology 2005;39(13):5010-4.
2005: Tomás C O'Riordan; James Hynes; Dmitri Yashunski; Gelii V Ponomarev; Dmitri B Papkovsky
Homogeneous assays for cellular proteases employing the platinum(II)-coproporphyrin label and time-resolved phosphorescence.
Analytical biochemistry 2005;342(1):111-9.
2004: John Alderman; James Hynes; Suzanne Floyd; Jan Krüger; Rosemary O'Connor; Dmitri B Papkovsky
A low-volume platform for cell-respirometric screening based on quenched-luminescence oxygen sensing.
Biosensors & bioelectronics 2004;19(11):1529-35.
2004: Dmitri B Papkovsky
Methods in optical oxygen sensing: protocols and critical analyses.
Methods in enzymology 2004;381():715-35.
2003: Martina Burke; Paul J O'Sullivan; Aleksi E Soini; Helen Berney; Dmitri B Papkovsky
Evaluation of the phosphorescent palladium(II)-coproporphyrin labels in separation-free hybridization assays.
Analytical biochemistry 2003;320(2):273-80.
2003: James Hynes; Suzanne Floyd; Aleksi E Soini; Rosemary O'Connor; Dmitri B Papkovsky
Fluorescence-based cell viability screening assays using water-soluble oxygen probes.
Journal of biomolecular screening 2003;8(3):264-72.
2002: Tomás C O'Riordan; Aleksi E Soini; Juhani T Soini; Dmitri B Papkovsky
Performance evaluation of the phosphorescent porphyrin label: solid-phase immunoassay of alpha-fetoprotein.
Analytical chemistry 2002;74(22):5845-50.
2002: Paul J O'Sullivan; Martina Burke; Aleksi E Soini; Dmitri B Papkovsky
Synthesis and evaluation of phosphorescent oligonucleotide probes for hybridisation assays.
Nucleic acids research 2002;30(21):e114.
2002: Aleksi E Soini; Lahja Seveus; Niko J Meltola; Dmitri B Papkovsky; Erkki Soini
Phosphorescent metalloporphyrins as labels in time-resolved luminescence microscopy: effect of mounting on emission intensity.
Microscopy research and technique 2002;58(2):125-31.
2002: Mary A Smiddy; M Fitzgerald; Joseph P Kerry; C K O' Sullivan; Dmitri B Papkovsky; G G Guilbault
Use of oxygen sensors to non-destructively measure the oxygen content in modified atmosphere and vacuum packed beef: impact of oxygen content on lipid oxidation.
Meat science 2002;61(3):285-90.
2001: Dmitri B Papkovsky; Gelii V Ponomarev
Spectral-luminescent study of the porphyrin-diketones and their complexes.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2001;57(9):1897-905.
2001: Tomás C O'Riordan; Aleksi E Soini; Dmitri B Papkovsky
Monofunctional derivatives of coproporphyrins for phosphorescent labeling of proteins and binding assays.
Analytical biochemistry 2001;290(2):366-75.
2000: Tomás C O'Riordan; D Buckley; Vladimir I Ogurtsov; Rosemary O'Connor; Dmitri B Papkovsky
A cell viability assay based on monitoring respiration by optical oxygen sensing.
Analytical biochemistry 2000;278(2):221-7.
2000: Dmitri B Papkovsky; Tomás C O'Riordan; Aleksi E Soini
Phosphorescent porphyrin probes in biosensors and sensitive bioassays.
Biochemical Society transactions 2000;28(2):74-7.
1999: Dmitri B Papkovsky; Tomás C O'Riordan; George G Guilbault
An immunosensor based on the glucose oxidase label and optical oxygen detection.
Analytical chemistry 1999;71(8):1568-73.