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William Pappano

Research Profile

Chemicals & Drugs

Living Beings

Mouse

Genes & Molecular Sequences

Amino Acid Sequences

Anatomy

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Publications

TOP 3
Elizabeth H Williams; William N Pappano; Adam Saunders; Min-Sung Kim; Daniel J Leahy; Philip A Beachy
Dally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal response.
Barry M Steiglitz; Jaclynn M Kreider; Elizabeth P Frankenburg; William N Pappano; Guy G Hoffman; Jeffrey A Meganck; Xiaowen Liang; Magnus Höök; David E Birk; Steven A Goldstein; Daniel S Greenspan
Procollagen C proteinase enhancer 1 genes are important determinants of the mechanical properties and geometry of bone and the ultrastructure of connective tissues.
Reema Jasuja; Benjamin Allen; William N Pappano; Alan C Rapraeger; Daniel S Greenspan
Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordin.

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All Publications

2010: Elizabeth H Williams; William N Pappano; Adam Saunders; Min-Sung Kim; Daniel J Leahy; Philip A Beachy
Dally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal response.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(13):5869-74.
2006: Barry M Steiglitz; Jaclynn M Kreider; Elizabeth P Frankenburg; William N Pappano; Guy G Hoffman; Jeffrey A Meganck; Xiaowen Liang; Magnus Höök; David E Birk; Steven A Goldstein; Daniel S Greenspan
Procollagen C proteinase enhancer 1 genes are important determinants of the mechanical properties and geometry of bone and the ultrastructure of connective tissues.
Molecular and cellular biology 2006;26(1):238-49.
2004: Reema Jasuja; Benjamin Allen; William N Pappano; Alan C Rapraeger; Daniel S Greenspan
Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordin.
The Journal of biological chemistry 2004;279(49):51289-97.
2003: Neil M Wolfman; Alexandra McPherron; William N Pappano; Monique V Davies; Kening Song; Kathy N Tomkinson; Jill F Wright; Liz Zhao; Suzanne M Sebald; Daniel S Greenspan; Se-Jin Lee
Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15842-6.
2003: William N Pappano; Barry M Steiglitz; Ian C Scott; Douglas R Keene; Daniel S Greenspan
Use of Bmp1/Tll1 doubly homozygous null mice and proteomics to identify and validate in vivo substrates of bone morphogenetic protein 1/tolloid-like metalloproteinases.
Molecular and cellular biology 2003;23(13):4428-38.
2003: Dallas P Veitch; Pasi Nokelainen; Kelly A McGowan; Thuong-Thuong Nguyen; Ngon E Nguyen; Robert Stephenson; William N Pappano; Douglas R Keene; Suzanne Spong; Daniel S Greenspan; Paul R Findell; M Peter Marinkovich
Mammalian tolloid metalloproteinase, and not matrix metalloprotease 2 or membrane type 1 metalloprotease, processes laminin-5 in keratinocytes and skin.
The Journal of biological chemistry 2003;278(18):15661-8.
2002: Anke Rattenholl; William N Pappano; Manuel Koch; Douglas R Keene; Karl Kadler; Takako Sasaki; Rupert Timpl; Robert E Burgeson; Daniel S Greenspan; Leena Bruckner-Tuderman
Proteinases of the bone morphogenetic protein-1 family convert procollagen VII to mature anchoring fibril collagen.
The Journal of biological chemistry 2002;277(29):26372-8.
2002: Christine Unsöld; William N Pappano; Yasutada Imamura; Barry M Steiglitz; Daniel S Greenspan
Biosynthetic processing of the pro-alpha 1(V)2pro-alpha 2(V) collagen heterotrimer by bone morphogenetic protein-1 and furin-like proprotein convertases.
The Journal of biological chemistry 2002;277(7):5596-602.
2001: Mehmet Ilhan Uzel; Ian C Scott; H Babakhanlou-Chase; Amitha H Palamakumbura; William N Pappano; Hsiang-Hsi Hong; Daniel S Greenspan; Philip C Trackman
Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures.
The Journal of biological chemistry 2001;276(25):22537-43.
2001: Ian C Scott; I L Blitz; William N Pappano; S A Maas; K W Cho; Daniel S Greenspan
Homologues of Twisted gastrulation are extracellular cofactors in antagonism of BMP signalling.
Nature 2001;410(6827):475-8.
2000: Ian C Scott; Yasutada Imamura; William N Pappano; J M Troedel; Anneliese D Recklies; Peter J Roughley; Daniel S Greenspan
Bone morphogenetic protein-1 processes probiglycan.
The Journal of biological chemistry 2000;275(39):30504-11.
2000: Ian C Scott; Barry M Steiglitz; TG Clark; William N Pappano; Daniel S Greenspan
Spatiotemporal expression patterns of mammalian chordin during postgastrulation embryogenesis and in postnatal brain.
Developmental dynamics : an official publication of the American Association of Anatomists 2000;217(4):449-56.
1999: Ian C Scott; I L Blitz; William N Pappano; Yasutada Imamura; TG Clark; Barry M Steiglitz; C L Thomas; S A Maas; Kazuhiko Takahara; K W Cho; Daniel S Greenspan
Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis.
Developmental biology 1999;213(2):283-300.
1998: William N Pappano; Ian C Scott; TG Clark; RL Eddy; TB Shows; Daniel S Greenspan
Coding sequence and expression patterns of mouse chordin and mapping of the cognate mouse chrd and human CHRD genes.
Genomics 1998;52(2):236-9.