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Jean-Luc Parent

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Christian Iorio-Morin; Pascale Germain; Jean-Luc Parent
Better management of Western blotting results using professional photo management software.
C Iorio-Morin; Pascale Labrecque; S Génier; P Germain; S Roy; Jean-Luc Parent
Thromboxane A2 modulates cisplatin-induced apoptosis through a Siva1-dependent mechanism.
Simon Roy; Sébastien J Roy; Maria Josep Agulleiro; José Miguel Cerdá-Reverter; Jean-Luc Parent; Sandra Pinard; Nicole Gallo-Payet
The C-terminal domains of melanocortin-2 receptor (MC2R) accessory proteins (MRAP1) influence their localization and ACTH-induced cAMP production.

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All Publications

2013: Christian Iorio-Morin; Pascale Germain; Jean-Luc Parent
Better management of Western blotting results using professional photo management software.
Electrophoresis 2013;34(8):1219-22.
2012: C Iorio-Morin; Pascale Labrecque; S Génier; P Germain; S Roy; Jean-Luc Parent
Thromboxane A2 modulates cisplatin-induced apoptosis through a Siva1-dependent mechanism.
Cell death and differentiation 2012;19(8):1347-57.
2012: Simon Roy; Sébastien J Roy; Maria Josep Agulleiro; José Miguel Cerdá-Reverter; Jean-Luc Parent; Sandra Pinard; Nicole Gallo-Payet
The C-terminal domains of melanocortin-2 receptor (MC2R) accessory proteins (MRAP1) influence their localization and ACTH-induced cAMP production.
General and comparative endocrinology 2012;176(2):265-74.
2011: Véronik Lachance; Sandra Munger; Andréane Cartier; Samuel Génier; Pascale Germain; Pascale Labrecque; Jean-Luc Parent
Regulation of β2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: modulation of Rab geranylgeranylation by the receptor.
The Journal of biological chemistry 2011;286(47):40802-13.
2011: Simon Roy; Sébastien Jean Roy; Louis-Daniel Taillefer; Jean-Luc Parent; Sandra Pinard; Mohamed Rached; Nicole Gallo-Payet
Mechanisms of melanocortin-2 receptor (MC2R) internalization and recycling in human embryonic kidney (hek) cells: identification of Key Ser/Thr (S/T) amino acids.
Molecular endocrinology (Baltimore, Md.) 2011;25(11):1961-77.
2011: Andréane Cartier; Pascale Labrecque; Geneviève Laroche; Audrey Parent; Jean-Luc Parent
WDR36 acts as a scaffold protein tethering a G-protein-coupled receptor, Gαq and phospholipase Cβ in a signalling complex.
Journal of cell science 2011;124(Pt 19):3292-304.
2011: Karine Mathurin; Maxime A Gallant; Pascale Germain; Hugues Allard-Chamard; Jessy Brisson; Christian Iorio-Morin; Artur J de Brum-Fernandes; Marc G Caron; Stephane Laporte; Jean-Luc Parent
An interaction between L-prostaglandin D synthase and arrestin increases PGD2 production.
The Journal of biological chemistry 2011;286(4):2696-706.
2010: Audrey Parent; Sébastien J Roy; Christian Iorio-Morin; Marie-Claude Lépine; Pascale Labrecque; Maxime A Gallant; Deborah Slipetz; Jean-Luc Parent
ANKRD13C acts as a molecular chaperone for G protein-coupled receptors.
The Journal of biological chemistry 2010;285(52):40838-51.
2010: Sébastien J Roy; Audrey Parent; Maxime A Gallant; Artur J de Brum-Fernandes; Jana Stanková; Jean-Luc Parent
Characterization of C-terminal tail determinants involved in CRTH2 receptor trafficking: identification of a recycling motif.
European journal of pharmacology 2010;630(1-3):10-8.
2010: Maxime A Gallant; Estelle Chamoux; Martine Bisson; Catarina Wolsen; Jean-Luc Parent; Sophie Roux; Artur J de Brum-Fernandes
Increased concentrations of prostaglandin D2 during post-fracture bone remodeling.
The Journal of rheumatology 2010;37(3):644-9.
2009: Audrey Parent; Emilie Hamelin; Pascale Germain; Jean-Luc Parent
Rab11 regulates the recycling of the beta2-adrenergic receptor through a direct interaction.
The Biochemical journal 2009;418(1):163-72.
2008: Audrey Parent; Geneviève Laroche; Emilie Hamelin; Jean-Luc Parent
RACK1 regulates the cell surface expression of the G protein-coupled receptor for thromboxane A(2).
Traffic (Copenhagen, Denmark) 2008;9(3):394-407.
2007: Geneviève Laroche; Patrick Giguère; Emilie Dupré; Gilles Dupuis; Jean-Luc Parent
The N-terminal coiled-coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with Galphaq.
Molecular and cellular biochemistry 2007;306(1-2):141-52.
2007: Patrick Giguère; Marie-Eve Turcotte; Emilie Hamelin; Audrey Parent; Jessy Brisson; Geneviève Laroche; Pascale Labrecque; Gilles Dupuis; Jean-Luc Parent
Peroxiredoxin-4 interacts with and regulates the thromboxane A(2) receptor.
FEBS letters 2007;581(20):3863-8.
2007: Maxime A Gallant; Deborah Slipetz; Emilie Hamelin; Moulay Driss Rochdi; Sébastien Talbot; Artur J de Brum-Fernandes; Jean-Luc Parent
Differential regulation of the signaling and trafficking of the two prostaglandin D2 receptors, prostanoid DP receptor and CRTH2.
European journal of pharmacology 2007;557(2-3):115-23.
2006: Patrick Giguère; Moulay Driss Rochdi; Geneviève Laroche; Emilie Dupré; Matthew R Whorton; Roger K Sunahara; Audrey Claing; Gilles Dupuis; Jean-Luc Parent
ARF6 activation by Galpha q signaling: Galpha q forms molecular complexes with ARNO and ARF6.
Cellular signalling 2006;18(11):1988-94.
2006: Josette A Hackett; Hugues Allard-Chamard; Patrice Sarrazin; Maria de Fatima Lucena; Maxime A Gallant; Isabelle Fortier; Moni Nader; Jean-Luc Parent; Ghassan Bkaily; Artur J de Brum-Fernandes
Prostaglandin production by human osteoclasts in culture.
The Journal of rheumatology 2006;33(7):1320-8.
2006: Rana Samadfam; Maxime A Gallant; Marie-Claude Miousse; Jean-Luc Parent; Artur J de Brum-Fernandes
Implication of prostaglandin receptors in the accumulation of osteoprotegerin in human osteoblast cultures.
The Journal of rheumatology 2006;33(6):1167-75.
2005: Geneviève Laroche; Marie-Claude Lépine; Caroline Thériault; Patrick Giguère; Vincent Giguère; Maxime A Gallant; Artur J de Brum-Fernandes; Jean-Luc Parent
Oligomerization of the alpha and beta isoforms of the thromboxane A2 receptor: relevance to receptor signaling and endocytosis.
Cellular signalling 2005;17(11):1373-83.
2005: Emilie Hamelin; Caroline Thériault; Geneviève Laroche; Jean-Luc Parent
The intracellular trafficking of the G protein-coupled receptor TPbeta depends on a direct interaction with Rab11.
The Journal of biological chemistry 2005;280(43):36195-205.
2005: Sophie Roux; Pascal Lambert-Comeau; Céline Saint-Pierre; Marie-Claude Lépine; Bassem Sawan; Jean-Luc Parent
Death receptors, Fas and TRAIL receptors, are involved in human osteoclast apoptosis.
Biochemical and biophysical research communications 2005;333(1):42-50.
2005: Geneviève Laroche; Moulay Driss Rochdi; Stephane Laporte; Jean-Luc Parent
Involvement of actin in agonist-induced endocytosis of the G protein-coupled receptor for thromboxane A2: overcoming of actin disruption by arrestin-3 but not arrestin-2.
The Journal of biological chemistry 2005;280(24):23215-24.
2005: Maxime A Gallant; Rana Samadfam; Josette A Hackett; John Antoniou; Jean-Luc Parent; Artur J de Brum-Fernandes
Production of prostaglandin D(2) by human osteoblasts and modulation of osteoprotegerin, RANKL, and cellular migration by DP and CRTH2 receptors.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(4):672-81.
2004: Vincent Giguère; Maxime A Gallant; Artur J de Brum-Fernandes; Jean-Luc Parent
Role of extracellular cysteine residues in dimerization/oligomerization of the human prostacyclin receptor.
European journal of pharmacology 2004;494(1):11-22.
2004: Caroline Thériault; Moulay Driss Rochdi; Jean-Luc Parent
Role of the Rab11-associated intracellular pool of receptors formed by constitutive endocytosis of the beta isoform of the thromboxane A2 receptor (TP beta).
Biochemistry 2004;43(19):5600-7.
2004: Moulay Driss Rochdi; Geneviève Laroche; Emilie Dupré; Patrick Giguère; Annie Lebel; Valérie Watier; Emilie Hamelin; Marie-Claude Lépine; Gilles Dupuis; Jean-Luc Parent
Nm23-H2 interacts with a G protein-coupled receptor to regulate its endocytosis through an Rac1-dependent mechanism.
The Journal of biological chemistry 2004;279(18):18981-9.
2003: Denis J Dupré; Zhangguo Chen; Christian Le Gouill; Caroline Thériault; Jean-Luc Parent; Marek Rola-Pleszczynski; Jana Stankova
Trafficking, ubiquitination, and down-regulation of the human platelet-activating factor receptor.
The Journal of biological chemistry 2003;278(48):48228-35.
2003: W Bruce Sneddon; Colin A Syme; Alessandro Bisello; Clara E Magyar; Moulay Driss Rochdi; Jean-Luc Parent; Edward J Weinman; Abdul B Abou-Samra; Peter A Friedman
Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50).
The Journal of biological chemistry 2003;278(44):43787-96.
2003: Moulay Driss Rochdi; Jean-Luc Parent
Galphaq-coupled receptor internalization specifically induced by Galphaq signaling. Regulation by EBP50.
The Journal of biological chemistry 2003;278(20):17827-37.
2002: Jacqueline Pérodin; Maud Deraët; Mannix Auger-Messier; Antony A Boucard; Lenka Rihakova; Marie-Eve Beaulieu; Pierre Lavigne; Jean-Luc Parent; Gaétan Guillemette; Richard Leduc; Emanuel Escher
Residues 293 and 294 are ligand contact points of the human angiotensin type 1 receptor.
Biochemistry 2002;41(48):14348-56.
2002: Moulay Driss Rochdi; Valérie Watier; Carole La Madeleine; Hiroko Nakata; Tohru Kozasa; Jean-Luc Parent
Regulation of GTP-binding protein alpha q (Galpha q) signaling by the ezrin-radixin-moesin-binding phosphoprotein-50 (EBP50).
The Journal of biological chemistry 2002;277(43):40751-9.
2001: Jean-Luc Parent; Pascale Labrecque; M Driss Rochdi; Jeffrey L Benovic
Role of the differentially spliced carboxyl terminus in thromboxane A2 receptor trafficking: identification of a distinct motif for tonic internalization.
The Journal of biological chemistry 2001;276(10):7079-85.
1999: Christopher V Carman; Jean-Luc Parent; Peter W Day; Alexey N Pronin; Pamela M Sternweis; Philip B Wedegaertner; Alfred G Gilman; Jeffrey L Benovic; Tohru Kozasa
Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2.
The Journal of biological chemistry 1999;274(48):34483-92.
1999: Charlotte K Billington; Ian P Hall; Stuart J Mundell; Jean-Luc Parent; Reynold A Panettieri; Jeffrey L Benovic; Raymond B Penn
Inflammatory and contractile agents sensitize specific adenylyl cyclase isoforms in human airway smooth muscle.
American journal of respiratory cell and molecular biology 1999;21(5):597-606.
1999: Michael J Orsini; Jean-Luc Parent; Stuart J Mundell; A Marchese; J L Benovic
Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization.
The Journal of biological chemistry 1999;274(43):31076-86.
1999: Christian Le Gouill; Jean-Luc Parent; C A Caron; Rémi Gaudreau; Leonid Volkov; Marek Rola-Pleszczynski; Jana Stanková
Selective modulation of wild type receptor functions by mutants of G-protein-coupled receptors.
The Journal of biological chemistry 1999;274(18):12548-54.
1999: Jean-Luc Parent; Pascale Labrecque; Michael J Orsini; Jeffrey L Benovic
Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced cooh terminus in agonist-promoted receptor internalization.
The Journal of biological chemistry 1999;274(13):8941-8.
1999: Maryse Thivierge; Jean-Luc Parent; Jana Stankova; Marek Rola-Pleszczynski
Modulation of formyl peptide receptor expression by IL-10 in human monocytes and neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3590-5.
1999: Raymond B Penn; Jean-Luc Parent; Alexey N Pronin; Reynold A Panettieri; Jeffrey L Benovic
Pharmacological inhibition of protein kinases in intact cells: antagonism of beta adrenergic receptor ligand binding by H-89 reveals limitations of usefulness.
The Journal of pharmacology and experimental therapeutics 1999;288(2):428-37.
1997: Christian Le Gouill; Jean-Luc Parent; Marek Rola-Pleszczynski; Jana Stanková
Structural and functional requirements for agonist-induced internalization of the human platelet-activating factor receptor.
The Journal of biological chemistry 1997;272(34):21289-95.
1997: Christian Le Gouill; Jean-Luc Parent; Marek Rola-Pleszczynski; Jana Stanková
Role of the Cys90, Cys95 and Cys173 residues in the structure and function of the human platelet-activating factor receptor.
FEBS letters 1997;402(2-3):203-8.
1997: Pierre Dagenais; Maryse Thivierge; Jean-Luc Parent; Jana Stankova; Marek Rola-Pleszczynski
Augmented expression of platelet-activating factor receptor gene by TNF-alpha through transcriptional activation in human monocytes.
Journal of leukocyte biology 1997;61(1):106-12.
1996: Maryse Thivierge; Jean-Luc Parent; Jana Stankova; Marek Rola-Pleszczynski
Modulation of human platelet-activating factor receptor gene expression by protein kinase C activation.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(10):4681-7.
1996: Jean-Luc Parent; C L Gouill; Emanuel Escher; Marek Rola-Pleszczynski; J Staková
Identification of transmembrane domain residues determinant in the structure-function relationship of the human platelet-activating factor receptor by site-directed mutagenesis.
The Journal of biological chemistry 1996;271(38):23298-303.
1996: Jean-Luc Parent; Christian Le Gouill; Artur J de Brum-Fernandes; Marek Rola-Pleszczynski; Jana Stanková
Mutations of two adjacent amino acids generate inactive and constitutively active forms of the human platelet-activating factor receptor.
The Journal of biological chemistry 1996;271(14):7949-55.
1996: Jean-Luc Parent; Christian Le Gouill; Marek Rola-Pleszczynski; Jana Stanková
Mutation of an aspartate at position 63 in the human platelet-activating factor receptor augments binding affinity but abolishes G-protein-coupling and inositol phosphate production.
Biochemical and biophysical research communications 1996;219(3):968-75.
1995: Marek Rola-Pleszczynski; Maryse Thivierge; S Ouellet; P Dagenais; Jean-Luc Parent; Jana Stankova
Cytokines and eicosanoids regulate PAF receptor gene expression.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():287-92.
1994: Jean-Luc Parent; Christian Le Gouill; Marek Rola-Pleszczynski; Jana Stanková
A highly efficient technique for cloning of refractory DNA fragments and polymerase chain reaction products.
Analytical biochemistry 1994;220(2):426-8.
1994: Christian Le Gouill; Jean-Luc Parent; Marek Rola-Pleszczynski; Jana Stankova
Analysis of recombinant plasmids by a modified alkaline lysis method.
Analytical biochemistry 1994;219(1):164.
1993: Jean-Luc Parent; Jana Stankova
Transforming growth factor-beta up-regulates the gene expression of the human platelet-activating factor receptor in monocytic and B cell lines.
Biochemical and biophysical research communications 1993;197(3):1443-9.