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Amadeo Parissenti

Research Profile

Physiology

Disorders

Breast Neoplasms

Chemicals & Drugs

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Publications

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Stephen R Armstrong; Stephanie Cull; Baoqing Guo; Katherine L McCallum; Rashmi Narendrula; Amadeo M Parissenti; Carita Lannér
Distinct genetic alterations occur in ovarian tumor cells selected for combined resistance to carboplatin and docetaxel.
Allan D Heibein; David A Maclean; Baoqing Guo; Jason A Sprowl; Amadeo M Parissenti
Role of aldo-keto reductases and other doxorubicin pharmacokinetic genes in doxorubicin resistance, DNA binding, and subcellular localization.
Jason A Sprowl; Lincoln Stein; Adam Tam; Kerry Reed; Stephen R Armstrong; Baoqing Guo; Stacey L Hembruff; Irina Kalatskaya; Carita Lanner; Amadeo M Parissenti
Alterations in tumor necrosis factor signaling pathways are associated with cytotoxicity and resistance to taxanes: a study in isogenic resistant tumor cells.

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2012: Stephen R Armstrong; Stephanie Cull; Baoqing Guo; Katherine L McCallum; Rashmi Narendrula; Amadeo M Parissenti; Carita Lannér
Distinct genetic alterations occur in ovarian tumor cells selected for combined resistance to carboplatin and docetaxel.
Journal of ovarian research 2012;5(1):40.
2012: Allan D Heibein; David A Maclean; Baoqing Guo; Jason A Sprowl; Amadeo M Parissenti
Role of aldo-keto reductases and other doxorubicin pharmacokinetic genes in doxorubicin resistance, DNA binding, and subcellular localization.
BMC cancer 2012;12():381.
2012: Jason A Sprowl; Lincoln Stein; Adam Tam; Kerry Reed; Stephen R Armstrong; Baoqing Guo; Stacey L Hembruff; Irina Kalatskaya; Carita Lanner; Amadeo M Parissenti
Alterations in tumor necrosis factor signaling pathways are associated with cytotoxicity and resistance to taxanes: a study in isogenic resistant tumor cells.
Breast cancer research : BCR 2012;14(1):R2.
2011: Kerry Reed; Amadeo M Parissenti
The effect of ABCB1 genetic variants on chemotherapy response in HIV and cancer treatment.
Pharmacogenomics 2011;12(10):1465-83.
2010: K Reed; Stacey L Hembruff; J A Sprowl; Amadeo M Parissenti
The temporal relationship between ABCB1 promoter hypomethylation, ABCB1 expression and acquisition of drug resistance.
The pharmacogenomics journal 2010;10(6):489-504.
2010: Kerry Reed; Matthew L Poulin; Liying Yan; Amadeo M Parissenti
Comparison of bisulfite sequencing PCR with pyrosequencing for measuring differences in DNA methylation.
Analytical biochemistry 2010;397(1):96-106.
2010: Amadeo M Parissenti; Judy-Anne W Chapman; Harriette J Kahn; Baoqing Guo; Lei Han; Patti O'Brien; Mark P Clemons; Roberta Jong; Rebecca Dent; Barbara Fitzgerald; Kathleen I Pritchard; Lois E Shepherd; Maureen E Trudeau
Association of low tumor RNA integrity with response to chemotherapy in breast cancer patients.
Breast cancer research and treatment 2010;119(2):347-56.
2009: Zachary W Veitch; Baoqing Guo; Stacey L Hembruff; Adam J Bewick; Allan D Heibein; Jamei Eng; Stephanie Cull; David A Maclean; Amadeo M Parissenti
Induction of 1C aldoketoreductases and other drug dose-dependent genes upon acquisition of anthracycline resistance.
Pharmacogenetics and genomics 2009;19(6):477-88.
2008: Kerry Reed; Stacey L Hembruff; Monique L Laberge; David J Villeneuve; Gilbert B. Côté; Amadeo M Parissenti
Hypermethylation of the ABCB1 downstream gene promoter accompanies ABCB1 gene amplification and increased expression in docetaxel-resistant MCF-7 breast tumor cells.
Epigenetics : official journal of the DNA Methylation Society 2008;3(5):270-80.
2008: Stacey L Hembruff; Monique L Laberge; David Villeneuve; Baoqing Guo; Zachary Veitch; Melanie Cecchetto; Amadeo M Parissenti
Role of drug transporters and drug accumulation in the temporal acquisition of drug resistance.
BMC cancer 2008;8():318.
2007: Jason A Sprowl; David Villeneuve; Baoqing Guo; Andrew J M Young; Stacey L Hembruff; Amadeo M Parissenti
Changes in expression of cell wall turnover genes accompany inhibition of chromosome segregation by bovine protein kinase C alpha expression in Saccharomyces cerevisiae.
Cell biology international 2007;31(10):1160-72.
2007: Amadeo M Parissenti; Stacey L Hembruff; David Villeneuve; Zachary Veitch; Baoqing Guo; Jamei Eng
Gene expression profiles as biomarkers for the prediction of chemotherapy drug response in human tumour cells.
Anti-cancer drugs 2007;18(5):499-523.
2006: Baoqing Guo; Kerry Reed; Amadeo M Parissenti
Scanning mutagenesis studies reveal multiple distinct regions within the human protein kinase C alpha regulatory domain important for phorbol ester-dependent activation of the enzyme.
Journal of molecular biology 2006;357(3):820-32.
2006: David Villeneuve; Stacey L Hembruff; Zachary Veitch; Melanie Cecchetto; William A Dew; Amadeo M Parissenti
cDNA microarray analysis of isogenic paclitaxel- and doxorubicin-resistant breast tumor cell lines reveals distinct drug-specific genetic signatures of resistance.
Breast cancer research and treatment 2006;96(1):17-39.
2005: Aseem Kumar; Anand Kumar; Paul Michael; Danielle Brabant; Amadeo M Parissenti; chilakamarti ramana; Xiulong Xu; Joseph E Parrillo
Human serum from patients with septic shock activates transcription factors STAT1, IRF1, and NF-kappaB and induces apoptosis in human cardiac myocytes.
The Journal of biological chemistry 2005;280(52):42619-26.
2005: Stacey L Hembruff; David Villeneuve; Amadeo M Parissenti
The optimization of quantitative reverse transcription PCR for verification of cDNA microarray data.
Analytical biochemistry 2005;345(2):237-49.
2004: Mary A Bewick; Michael S C Conlon; H Lee; Amadeo M Parissenti; Lianfeng Zhang; Stefan Gluck; Robert M Lafrenie
Evaluation of sICAM-1, sVCAM-1, and sE-Selectin levels in patients with metastatic breast cancer receiving high-dose chemotherapy.
Stem cells and development 2004;13(3):281-94.
2004: Baoqing Guo; David Villeneuve; Stacey L Hembruff; Angie F Kirwan; David E Blais; Michel Bonin; Amadeo M Parissenti
Cross-resistance studies of isogenic drug-resistant breast tumor cell lines support recent clinical evidence suggesting that sensitivity to paclitaxel may be strongly compromised by prior doxorubicin exposure.
Breast cancer research and treatment 2004;85(1):31-51.
2004: David Villeneuve; Amadeo M Parissenti
The use of DNA microarrays to investigate the pharmacogenomics of drug response in living systems.
Current topics in medicinal chemistry 2004;4(13):1329-45.
2003: Baoqing Guo; Stacey L Hembruff; David Villeneuve; Angie F Kirwan; Amadeo M Parissenti
Potent killing of paclitaxel- and doxorubicin-resistant breast cancer cells by calphostin C accompanied by cytoplasmic vacuolization.
Breast cancer research and treatment 2003;82(2):125-41.
2003: Angie F Kirwan; Ashley C Bibby; Thierry Mvilongo; Heimo Riedel; Thomas Burke; Sherri Z Millis; Amadeo M Parissenti
Inhibition of protein kinase C catalytic activity by additional regions within the human protein kinase Calpha-regulatory domain lying outside of the pseudosubstrate sequence.
The Biochemical journal 2003;373(Pt 2):571-81.
2003: Amadeo M Parissenti; Heimo Riedel
Yeast as a host to screen for modulators and regulatory regions of mammalian protein kinase C isoforms.
Methods in molecular biology (Clifton, N.J.) 2003;233():491-516.
2001: Mary A Bewick; Michael S C Conlon; Amadeo M Parissenti; H Lee; Lianfeng Zhang; Stefan Gluck; Robert M Lafrenie
Soluble Fas (CD95) is a prognostic factor in patients with metastatic breast cancer undergoing high-dose chemotherapy and autologous stem cell transplantation.
Journal of hematotherapy & stem cell research 2001;10(6):759-68.
2001: Mary A Bewick; Michael S C Conlon; S Gerard; H Lee; Amadeo M Parissenti; Lianfeng Zhang; Stefan Gluck; Robert M Lafrenie
HER-2 expression is a prognostic factor in patients with metastatic breast cancer treated with a combination of high-dose cyclophosphamide, mitoxantrone, paclitaxel and autologous blood stem cell support.
Bone marrow transplantation 2001;27(8):847-53.
2000: BD Leinweber; Amadeo M Parissenti; Cynthia Gallant; Samudra S Gangopadhyay; AF Kirwan-Rhude; Paul C Leavis; Kathleen G Morgan
Regulation of protein kinase C by the cytoskeletal protein calponin.
The Journal of biological chemistry 2000;275(51):40329-36.
2000: A Chadderton; David Villeneuve; Stefan Gluck; AF Kirwan-Rhude; B R Gannon; D E Blais; Amadeo M Parissenti
Role of specific apoptotic pathways in the restoration of paclitaxel-induced apoptosis by valspodar in doxorubicin-resistant MCF-7 breast cancer cells.
Breast cancer research and treatment 2000;59(3):231-44.
1999: Amadeo M Parissenti; B R Gannon; David Villeneuve; AF Kirwan-Rhude; A Chadderton; Stefan Gluck
Lack of modulation of MDR1 gene expression by dominant inhibition of cAMP-dependent protein kinase in doxorubicin-resistant MCF-7 breast cancer cells.
International journal of cancer. Journal international du cancer 1999;82(6):893-900.
1999: Amadeo M Parissenti; David Villeneuve; AF Kirwan-Rhude; D Busch
Carbon source-dependent regulation of cell growth by murine protein kinase C epsilon expression in Saccharomyces cerevisiae.
Journal of cellular physiology 1999;178(2):216-26.
1998: Amadeo M Parissenti; Angie F Kirwan; S A Kim; C M Colantonio; Bernard P Schimmer
Inhibitory properties of the regulatory domains of human protein kinase Calpha and mouse protein kinase Cepsilon.
The Journal of biological chemistry 1998;273(15):8940-5.
1996: Amadeo M Parissenti; A F Kirwan; S A Kim; C M Colantonio; Bernard P Schimmer
Molecular strategies for the dominant inhibition of protein kinase C.
Endocrine research 1996;22(4):621-30.
1996: Amadeo M Parissenti; S A Kim; C M Colantonio; A L Snihura; Bernard P Schimmer
Regulatory domain of human protein kinase C alpha dominantly inhibits protein kinase C beta-I-regulated growth and morphology in Saccharomyces cerevisiae.
Journal of cellular physiology 1996;166(3):609-17.
1993: Amadeo M Parissenti; K L Parker; Bernard P Schimmer
Identification of promoter elements in the mouse 21-hydroxylase (Cyp21) gene that require a functional cyclic adenosine 3',5'-monophosphate-dependent protein kinase.
Molecular endocrinology (Baltimore, Md.) 1993;7(2):283-90.