FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Edwards Park

Research Profile

Living Beings

Chemicals & Drugs

Physiology

Anatomy

Concepts & Ideas

Molecular Sequence Data

Co-author Network

Publications

TOP 3
Ruishan Wang; Robert W Williams; Lianteng Zhi; Li Liu; Edwards A Park; Narayan R Bhat; Hansruedi Büeler; Shiyong Diao; Young-Don Kwak; Jing Jing Li; Francesca-Fang Liao
Metabolic Stress Modulates Alzheimer's β-Secretase Gene Transcription via SIRT1-PPARγ-PGC-1 in Neurons.
Shalini Thakran; Pragya Sharma; Ramy R Attia; Xiong Deng; Marshall B Elam; Roderick T Hori; Edwards A Park
Role of sirtuin 1 in the regulation of hepatic gene expression by thyroid hormone.
Xiong Deng; Qingming Dong; Insug O-Sullivan; Edwards A Park; Rajendra Raghow; Terry G Unterman; J Bradley Williams; Wenwei Zhang; Marshall B Elam
FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Edwards Park (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Ruishan Wang; Robert W Williams; Lianteng Zhi; Li Liu; Edwards A Park; Narayan R Bhat; Hansruedi Büeler; Shiyong Diao; Young-Don Kwak; Jing Jing Li; Francesca-Fang Liao
Metabolic Stress Modulates Alzheimer's β-Secretase Gene Transcription via SIRT1-PPARγ-PGC-1 in Neurons.
Cell metabolism 2013;17(5):685-94.
2013: Shalini Thakran; Pragya Sharma; Ramy R Attia; Xiong Deng; Marshall B Elam; Roderick T Hori; Edwards A Park
Role of sirtuin 1 in the regulation of hepatic gene expression by thyroid hormone.
The Journal of biological chemistry 2013;288(2):807-18.
2012: Xiong Deng; Qingming Dong; Insug O-Sullivan; Edwards A Park; Rajendra Raghow; Terry G Unterman; J Bradley Williams; Wenwei Zhang; Marshall B Elam
FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c.
The Journal of biological chemistry 2012;287(24):20132-43.
2011: Ramy R Attia; George A Cook; Xiong Deng; Marshall B Elam; Jacob E Friedman; Rachel C Janssen; Jae Seung Lee; Pragya Sharma; Edwards A Park
Regulation of pyruvate dehydrogenase kinase 4 (PDK4) by CCAAT/enhancer-binding protein beta (C/EBPbeta).
The Journal of biological chemistry 2011;286(27):23799-807.
2011: Khosrow Kashfi; Randall L Mynatt; Edwards A Park; George A Cook
Membrane microenvironment regulation of carnitine palmitoyltranferases I and II.
Biochemical Society transactions 2011;39(3):833-7.
2011: Anne-Marie Estes; Kathleen McAllen; Michael S Parker; Renu Sah; Trevor Sweatman; Edwards A Park; Ambikaipakan Balasubramaniam; Floyd R Sallee; Mary W Walker; Steven L Parker
Maintenance of Y receptor dimers in epithelial cells depends on interaction with G-protein heterotrimers.
Amino acids 2011;40(2):371-80.
2011: Michael S Parker; Edwards A Park; Floyd R Sallee; Steven L Parker
Two intracellular helices of G-protein coupling receptors could generally support oligomerization and coupling with transducers.
Amino acids 2011;40(2):261-8.
2010: Shulan Song; Ramy R Attia; Sara Connaughton; Melissa I Niesen; Gene C Ness; Marshall B Elam; Roderick T Hori; George A Cook; Edwards A Park
Peroxisome proliferator activated receptor alpha (PPARalpha) and PPAR gamma coactivator (PGC-1alpha) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements.
Molecular and cellular endocrinology 2010;325(1-2):54-63.
2010: Marshall B Elam; Chandrahasa Yellaturu; George E Howell; Xiong Deng; George S M Cowan; Poonam Kumar; Edwards A Park; M Lloyd Hiler; Henry G Wilcox; Thomas A Hughes; George A Cook; Rajendra Raghow
Dysregulation of sterol regulatory element binding protein-1c in livers of morbidly obese women is associated with altered suppressor of cytokine signaling-3 and signal transducer and activator of transcription-1 signaling.
Metabolism: clinical and experimental 2010;59(4):587-98.
2010: Sara Connaughton; Farhana Chowdhury; Ramy R Attia; Shulan Song; Yi Zhang; Marshall B Elam; George A Cook; Edwards A Park
Regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expression by glucocorticoids and insulin.
Molecular and cellular endocrinology 2010;315(1-2):159-67.
2010: Ramy R Attia; Sara Connnaughton; Lindsey R Boone; Fang Wang; Marshall B Elam; Gene C Ness; George A Cook; Edwards A Park
Regulation of pyruvate dehydrogenase kinase 4 (PDK4) by thyroid hormone: role of the peroxisome proliferator-activated receptor gamma coactivator (PGC-1 alpha).
The Journal of biological chemistry 2010;285(4):2375-85.
2009: George Howell; Xiong Deng; Chandrahasa R Yellaturu; Edwards A Park; Henry G Wilcox; Rajendra Raghow; Marshall B Elam
N-3 polyunsaturated fatty acids suppress insulin-induced SREBP-1c transcription via reduced trans-activating capacity of LXRalpha.
Biochimica et biophysica acta 2009;1791(12):1190-6.
2009: Chandrahasa R Yellaturu; Xiong Deng; Edwards A Park; Rajendra Raghow; Marshall B Elam
Insulin enhances the biogenesis of nuclear sterol regulatory element-binding protein (SREBP)-1c by posttranscriptional down-regulation of Insig-2A and its dissociation from SREBP cleavage-activating protein (SCAP).SREBP-1c complex.
The Journal of biological chemistry 2009;284(46):31726-34.
2009: Harihara S K Potula; Dong Wang; Dong Van Quyen; Nikhlesh K Singh; Venkatesh Kundumani-Sridharan; Manjula Karpurapu; Edwards A Park; Wayne C Glasgow; Gadiparthi N Rao
Src-dependent STAT-3-mediated expression of monocyte chemoattractant protein-1 is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration.
The Journal of biological chemistry 2009;284(45):31142-55.
2009: Marshall B Elam; George S M Cowan; Robert J. Rooney; M Lloyd Hiler; Chandrahasa R Yellaturu; Xiong Deng; George E Howell; Edwards A Park; Ivan C Gerling; Divyan Patel; J Christopher Corton; Lauren M Cagen; Henry G Wilcox; Malay Gandhi; Micheal H Bahr; Micheal C Allan; Linus A Wodi; George A Cook; Thomas A Hughes; Rajendra Raghow
Hepatic gene expression in morbidly obese women: implications for disease susceptibility.
Obesity (Silver Spring, Md.) 2009;17(8):1563-73.
2009: Chandrahasa R Yellaturu; Xiong Deng; Lauren M Cagen; Henry G Wilcox; Charles M Mansbach; Shadab A Siddiqi; Edwards A Park; Rajendra Raghow; Marshall B Elam
Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles.
The Journal of biological chemistry 2009;284(12):7518-32.
2008: Rajendra Raghow; Chandrahasa R Yellaturu; Xiong Deng; Edwards A Park; Marshall B Elam
SREBPs: the crossroads of physiological and pathological lipid homeostasis.
Trends in endocrinology and metabolism: TEM 2008;19(2):65-73.
2007: Xiong Deng; Chandrahasa R Yellaturu; Lauren M Cagen; Henry G Wilcox; Edwards A Park; Rajendra Raghow; Marshall B Elam
Expression of the rat sterol regulatory element-binding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1).
The Journal of biological chemistry 2007;282(24):17517-29.
2007: Prabodh Sadana; Edwards A Park
Characterization of the transactivation domain in the peroxisome-proliferator-activated receptor gamma co-activator (PGC-1).
The Biochemical journal 2007;403(3):511-8.
2007: Prabodh Sadana; Yi Zhang; Shulan Song; George A Cook; Marshall B Elam; Edwards A Park
Regulation of carnitine palmitoyltransferase I (CPT-Ialpha) gene expression by the peroxisome proliferator activated receptor gamma coactivator (PGC-1) isoforms.
Molecular and cellular endocrinology 2007;267(1-2):6-16.
2006: Yi Zhang; Ke Ma; Prabodh Sadana; Farhana Chowdhury; Stephanie Gaillard; Fang Wang; Donald P McDonnell; Terry G Unterman; Marshall B Elam; Edwards A Park
Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression.
The Journal of biological chemistry 2006;281(52):39897-906.
2005: Ke Ma; Yi Zhang; Marshall B Elam; George A Cook; Edwards A Park
Cloning of the rat pyruvate dehydrogenase kinase 4 gene promoter: activation of pyruvate dehydrogenase kinase 4 by the peroxisome proliferator-activated receptor gamma coactivator.
The Journal of biological chemistry 2005;280(33):29525-32.
2005: Chandrahasa R Yellaturu; Xiong Deng; Lauren M Cagen; Henry G Wilcox; Edwards A Park; Rajendra Raghow; Marshall B Elam
Posttranslational processing of SREBP-1 in rat hepatocytes is regulated by insulin and cAMP.
Biochemical and biophysical research communications 2005;332(1):174-80.
2005: Lauren M Cagen; Xiong Deng; Henry G Wilcox; Edwards A Park; Rajendra Raghow; Marshall B Elam
Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements.
The Biochemical journal 2005;385(Pt 1):207-16.
2004: Yi Zhang; Ke Ma; Shulan Song; Marshall B Elam; George A Cook; Edwards A Park
Peroxisomal proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1 alpha) enhances the thyroid hormone induction of carnitine palmitoyltransferase I (CPT-I alpha).
The Journal of biological chemistry 2004;279(52):53963-71.
2004: Xiong Deng; Marshall B Elam; Henry G Wilcox; Lauren M Cagen; Edwards A Park; Rajendra Raghow; Divyen Patel; Poonam Kumar; Ali Sheybani; James C Russell
Dietary olive oil and menhaden oil mitigate induction of lipogenesis in hyperinsulinemic corpulent JCR:LA-cp rats: microarray analysis of lipid-related gene expression.
Endocrinology 2004;145(12):5847-61.
2004: Shulan Song; Yi Zhang; Ke Ma; Loretta Jackson-Hayes; Eduard Lavrentyev; George A Cook; Marshall B Elam; Edwards A Park
Peroxisomal proliferator activated receptor gamma coactivator (PGC-1alpha) stimulates carnitine palmitoyltransferase I (CPT-Ialpha) through the first intron.
Biochimica et biophysica acta 2004;1679(2):164-73.
2003: Meredith L Moore; Edwards A Park; Jeanie B McMillin
Upstream stimulatory factor represses the induction of carnitine palmitoyltransferase-Ibeta expression by PGC-1.
The Journal of biological chemistry 2003;278(19):17263-8.
2003: Loretta Jackson-Hayes; Shulan Song; Eduard Lavrentyev; Michelle S Jansen; F Bradley Hillgartner; Liquin Tian; Philip A Wood; George A Cook; Edwards A Park
A thyroid hormone response unit formed between the promoter and first intron of the carnitine palmitoyltransferase-Ialpha gene mediates the liver-specific induction by thyroid hormone.
The Journal of biological chemistry 2003;278(10):7964-72.
2002: Luis A Jurado; Shulan Song; William J Roesler; Edwards A Park
Conserved amino acids within CCAAT enhancer-binding proteins (C/EBP(alpha) and beta) regulate phosphoenolpyruvate carboxykinase (PEPCK) gene expression.
The Journal of biological chemistry 2002;277(31):27606-12.
2002: Xiong Deng; Lauren M Cagen; Henry G Wilcox; Edwards A Park; Rajendra Raghow; Marshall B Elam
Regulation of the rat SREBP-1c promoter in primary rat hepatocytes.
Biochemical and biophysical research communications 2002;290(1):256-62.
2001: George A Cook; T L Edwards; Michelle S Jansen; Suleiman W Bahouth; Henry G Wilcox; Edwards A Park
Differential regulation of carnitine palmitoyltransferase-I gene isoforms (CPT-I alpha and CPT-I beta) in the rat heart.
Journal of molecular and cellular cardiology 2001;33(2):317-29.
2000: Michelle S Jansen; George A Cook; Shulan Song; Edwards A Park
Thyroid hormone regulates carnitine palmitoyltransferase Ialpha gene expression through elements in the promoter and first intron.
The Journal of biological chemistry 2000;275(45):34989-97.
1999: George A Cook; Edwards A Park
Expression and regulation of carnitine palmitoyltransferase-Ialpha and -Ibeta genes.
The American journal of the medical sciences 1999;318(1):43-8.
1999: M L Steffen; Wilbur R Harrison; Frederick F Elder; George A Cook; Edwards A Park
Expression of the rat liver carnitine palmitoyltransferase I (CPT-Ialpha) gene is regulated by Sp1 and nuclear factor Y: chromosomal localization and promoter characterization.
The Biochemical journal 1999;340 ( Pt 2)():425-32.
1999: Edwards A Park; Shulan Song; C Vinson; William J Roesler
Role of CCAAT enhancer-binding protein beta in the thyroid hormone and cAMP induction of phosphoenolpyruvate carboxykinase gene transcription.
The Journal of biological chemistry 1999;274(1):211-7.
1998: William J Roesler; Edwards A Park; Pamela J McFie
Characterization of CCAAT/enhancer-binding protein alpha as a cyclic AMP-responsive nuclear regulator.
The Journal of biological chemistry 1998;273(24):14950-7.
1998: Edwards A Park; George A Cook
Differential regulation in the heart of mitochondrial carnitine palmitoyltransferase-I muscle and liver isoforms.
Molecular and cellular biochemistry 1998;180(1-2):27-32.
1998: Edwards A Park; M L Steffen; Shulan Song; Vicki M Park; George A Cook
Cloning and characterization of the promoter for the liver isoform of the rat carnitine palmitoyltransferase I (L-CPT I) gene.
The Biochemical journal 1998;330 ( Pt 1)():217-24.
1998: Suleiman W Bahouth; Michael J Beauchamp; Edwards A Park
Identification of a retinoic acid response domain involved in the activation of the beta 1-adrenergic receptor gene by retinoic acid in F9 teratocarcinoma cells.
Biochemical pharmacology 1998;55(2):215-25.
1998: William J Roesler; Edwards A Park
Hormone response units: one plus one equals more than two.
Molecular and cellular biochemistry 1998;178(1-2):1-8.
1997: Suleiman W Bahouth; X Cui; Michael J Beauchamp; Edwards A Park
Thyroid hormone induces beta1-adrenergic receptor gene transcription through a direct repeat separated by five nucleotides.
Journal of molecular and cellular cardiology 1997;29(12):3223-37.
1997: Suleiman W Bahouth; X Cui; Michael J Beauchamp; H Shimomura; S T George; Edwards A Park
Promoter analysis of the rat beta1-adrenergic receptor gene identifies sequences involved in basal expression.
Molecular pharmacology 1997;51(4):620-9.
1997: Edwards A Park; Shulan Song; M Olive; William J Roesler
CCAAT-enhancer-binding protein alpha (C/EBP alpha) is required for the thyroid hormone but not the retinoic acid induction of phosphoenolpyruvate carboxykinase (PEPCK) gene transcription.
The Biochemical journal 1997;322 ( Pt 1)():343-9.
1996: Suleiman W Bahouth; Edwards A Park; Michael J Beauchamp; X Cui; C C Malbon
Identification of a glucocorticoid repressor domain in the rat beta 1-adrenergic receptor gene.
Receptors & signal transduction 1996;6(3-4):141-9.
1995: Edwards A Park; R L Mynatt; George A Cook; K Kashfi
Insulin regulates enzyme activity, malonyl-CoA sensitivity and mRNA abundance of hepatic carnitine palmitoyltransferase-I.
The Biochemical journal 1995;310 ( Pt 3)():853-8.
1995: Edwards A Park; D C Jerden; Suleiman W Bahouth
Regulation of phosphoenolpyruvate carboxykinase gene transcription by thyroid hormone involves two distinct binding sites in the promoter.
The Biochemical journal 1995;309 ( Pt 3)():913-9.
1994: A L Gurney; Edwards A Park; J Liu; Marta Giralt; M M McGrane; Yashomati M Patel; D R Crawford; S E Nizielski; S Savon; Richard W Hanson
Metabolic regulation of gene transcription.
The Journal of nutrition 1994;124(8 Suppl):1533S-1539S.
1994: R L Mynatt; Edwards A Park; F E Thorngate; H K Das; George A Cook
Changes in carnitine palmitoyltransferase-I mRNA abundance produced by hyperthyroidism and hypothyroidism parallel changes in activity.
Biochemical and biophysical research communications 1994;201(2):932-7.
1993: Edwards A Park; A L Gurney; S E Nizielski; Parvin Hakimi; Z Cao; A Moorman; Richard W Hanson
Relative roles of CCAAT/enhancer-binding protein beta and cAMP regulatory element-binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase (GTP).
The Journal of biological chemistry 1993;268(1):613-9.
1992: P S Brady; Edwards A Park; J S Liu; Richard W Hanson; LJ Brady
Isolation and characterization of the promoter for the gene coding for the 68 kDa carnitine palmitoyltransferase from the rat.
The Biochemical journal 1992;286 ( Pt 3)():779-83.
1992: A L Gurney; Edwards A Park; Marta Giralt; J Liu; Richard W Hanson
Opposing actions of Fos and Jun on transcription of the phosphoenolpyruvate carboxykinase (GTP) gene. Dominant negative regulation by Fos.
The Journal of biological chemistry 1992;267(25):18133-9.
1992: P S Brady; Edwards A Park; Richard W Hanson; LJ Brady
Multiple regulatory elements characterize the promoter region of the 68 kDa carnitine palmitoyltransferase in the rat and the human.
Progress in clinical and biological research 1992;375():175-81.
1991: Marta Giralt; Edwards A Park; A L Gurney; J S Liu; Parvin Hakimi; Richard W Hanson
Identification of a thyroid hormone response element in the phosphoenolpyruvate carboxykinase (GTP) gene. Evidence for synergistic interaction between thyroid hormone and cAMP cis-regulatory elements.
The Journal of biological chemistry 1991;266(32):21991-6.
1991: J S Liu; Edwards A Park; A L Gurney; William J Roesler; Richard W Hanson
Cyclic AMP induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription is mediated by multiple promoter elements.
The Journal of biological chemistry 1991;266(28):19095-102.
1991: Maria Hatzoglou; F Bosch; Edwards A Park; Richard W Hanson
Hormonal control of interacting promoters introduced into cells by retroviruses.
The Journal of biological chemistry 1991;266(13):8416-25.
1990: M M McGrane; J S Yun; A F Moorman; W H Lamers; G K Hendrick; Baha Arafah; Edwards A Park; Thomas E Wagner; Richard W Hanson
Metabolic effects of developmental, tissue-, and cell-specific expression of a chimeric phosphoenolpyruvate carboxykinase (GTP)/bovine growth hormone gene in transgenic mice.
The Journal of biological chemistry 1990;265(36):22371-9.
1990: Edwards A Park; William J Roesler; J Liu; Dwight J Klemm; A L Gurney; J D Thatcher; J Shuman; Alan D Friedman; Richard W Hanson
The role of the CCAAT/enhancer-binding protein in the transcriptional regulation of the gene for phosphoenolpyruvate carboxykinase (GTP).
Molecular and cellular biology 1990;10(12):6264-72.
1990: F Bosch; Maria Hatzoglou; Edwards A Park; Richard W Hanson
Vanadate inhibits expression of the gene for phosphoenolpyruvate carboxykinase (GTP) in rat hepatoma cells.
The Journal of biological chemistry 1990;265(23):13677-82.
1990: Dwight J Klemm; William J Roesler; J S Liu; Edwards A Park; Richard W Hanson
In vitro analysis of promoter elements regulating transcription of the phosphoenolpyruvate carboxykinase (GTP) gene.
Molecular and cellular biology 1990;10(2):480-5.
1990: M M McGrane; J S Yun; William J Roesler; Edwards A Park; Thomas E Wagner; Richard W Hanson
Developmental regulation and tissue-specific expression of a chimaeric phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic animals.
Journal of reproduction and fertility. Supplement 1990;41():17-23.