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Barbara Abbott

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Barbara D Abbott; Kaberi P Das; Katoria Tatum-Gibbs; Andrew M Watkins; Carmen R Wood; Christopher Lau
Effects of perfluorooctanoic acid (PFOA) on expression of peroxisome proliferator-activated receptors (PPAR) and nuclear receptor-regulated genes in fetal and postnatal CD-1 mouse tissues.
Cynthia J Wolf; Christopher Lau; Judith E Schmid; Barbara D Abbott
Activation of mouse and human peroxisome proliferator-activated receptor-alpha (PPARα) by perfluoroalkyl acids (PFAAs): further investigation of C4-C12 compounds.
Barbara D Abbott
The etiology of cleft palate: a 50-year search for mechanistic and molecular understanding.

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2012: Barbara D Abbott; Kaberi P Das; Katoria Tatum-Gibbs; Andrew M Watkins; Carmen R Wood; Christopher Lau
Effects of perfluorooctanoic acid (PFOA) on expression of peroxisome proliferator-activated receptors (PPAR) and nuclear receptor-regulated genes in fetal and postnatal CD-1 mouse tissues.
Reproductive toxicology (Elmsford, N.Y.) 2012;33(4):491-505.
2012: Cynthia J Wolf; Christopher Lau; Judith E Schmid; Barbara D Abbott
Activation of mouse and human peroxisome proliferator-activated receptor-alpha (PPARα) by perfluoroalkyl acids (PFAAs): further investigation of C4-C12 compounds.
Reproductive toxicology (Elmsford, N.Y.) 2012;33(4):546-51.
2010: Barbara D Abbott
The etiology of cleft palate: a 50-year search for mechanistic and molecular understanding.
Birth defects research. Part B, Developmental and reproductive toxicology 2010;89(4):266-74.
2010: Mitchell B Rosen; Judith R Schmid; J Christopher Corton; Robert D Zehr; Kaberi P Das; Barbara D Abbott; Christopher Lau
Gene Expression Profiling in Wild-Type and PPARα-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPARα-Independent Effects.
PPAR research 2010;2010():.
2010: Barbara D Abbott; Carmen R Wood; Andrew M Watkins; Kaberi P Das; Christopher S Lau
Peroxisome proliferator-activated receptors alpha, Beta, and gamma mRNA and protein expression in human fetal tissues.
PPAR research 2010;2010():.
2009: Sally S White; Kayoko Kato; Lily T Jia; Brian J Basden; Antonia M Calafat; Erin P Hines; JP Stanko; Cynthia J Wolf; Barbara D Abbott; Suzanne E Fenton
Effects of perfluorooctanoic acid on mouse mammary gland development and differentiation resulting from cross-foster and restricted gestational exposures.
Reproductive toxicology (Elmsford, N.Y.) 2009;27(3-4):289-98.
2009: Barbara D Abbott
Review of the expression of peroxisome proliferator-activated receptors alpha (PPAR alpha), beta (PPAR beta), and gamma (PPAR gamma) in rodent and human development.
Reproductive toxicology (Elmsford, N.Y.) 2009;27(3-4):246-57.
2009: Barbara D Abbott; Cynthia J Wolf; Kaberi P Das; Robert D Zehr; Judith E Schmid; Andrew B Lindstrom; Mark J Strynar; Christopher Lau
Developmental toxicity of perfluorooctane sulfonate (PFOS) is not dependent on expression of peroxisome proliferator activated receptor-alpha (PPAR alpha) in the mouse.
Reproductive toxicology (Elmsford, N.Y.) 2009;27(3-4):258-65.
2008: Cynthia J Wolf; Margy L Takacs; Judith E Schmid; Christopher Lau; Barbara D Abbott
Activation of mouse and human peroxisome proliferator-activated receptor alpha by perfluoroalkyl acids of different functional groups and chain lengths.
Toxicological sciences : an official journal of the Society of Toxicology 2008;106(1):162-71.
2008: Douglas Wolf; Tanya Moore; Barbara D Abbott; Mitchell B Rosen; Kaberi P Das; Robert D Zehr; Andrew B Lindstrom; Mark J Strynar; Christopher Lau
Comparative hepatic effects of perfluorooctanoic acid and WY 14,643 in PPAR-alpha knockout and wild-type mice.
Toxicologic pathology 2008;36(4):632-9.
2008: Mitchell B Rosen; Barbara D Abbott; Douglas Wolf; J Christopher Corton; Carmen R Wood; Judith E Schmid; Kaberi P Das; Robert D Zehr; Eric T Blair; Christopher Lau
Gene profiling in the livers of wild-type and PPARalpha-null mice exposed to perfluorooctanoic acid.
Toxicologic pathology 2008;36(4):592-607.
2007: Barbara D Abbott; Cynthia J Wolf; Judith E Schmid; Kaberi P Das; Robert D Zehr; Laurence Helfant; Shoji Nakayama; Andrew B Lindstrom; Mark J Strynar; Christopher Lau
Perfluorooctanoic acid induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha.
Toxicological sciences : an official journal of the Society of Toxicology 2007;98(2):571-81.
2007: Cynthia J Wolf; Suzanne E Fenton; Judith E Schmid; Antonia M Calafat; Zsuzsanna Kuklenyik; Xavier A Bryant; Julie R Thibodeaux; Kaberi P Das; Sally S White; Christopher S Lau; Barbara D Abbott
Developmental toxicity of perfluorooctanoic acid in the CD-1 mouse after cross-foster and restricted gestational exposures.
Toxicological sciences : an official journal of the Society of Toxicology 2007;95(2):462-73.
2007: Margy L Takacs; Barbara D Abbott
Activation of mouse and human peroxisome proliferator-activated receptors (alpha, beta/delta, gamma) by perfluorooctanoic acid and perfluorooctane sulfonate.
Toxicological sciences : an official journal of the Society of Toxicology 2007;95(1):108-17.
2005: Barbara D Abbott; Angela R Buckalew; Korin E Leffler
Effects of epidermal growth factor (EGF), transforming growth factor-alpha (TGFalpha), and 2,3,7,8-tetrachlorodibenzo-p-dioxin on fusion of embryonic palates in serum-free organ culture using wild-type, EGF knockout, and TGFalpha knockout mouse strains.
Birth defects research. Part A, Clinical and molecular teratology 2005;73(6):447-54.
2005: Barbara D Abbott; Deborah S Best; Michael G Narotsky
Teratogenic effects of retinoic acid are modulated in mice lacking expression of epidermal growth factor and transforming growth factor-alpha.
Birth defects research. Part A, Clinical and molecular teratology 2005;73(4):204-17.
2004: Jerome Goldman; Ashley S Murr; Angela R Buckalew; Judith E Schmid; Barbara D Abbott
Methoxychlor-induced alterations in the histological expression of angiogenic factors in pituitary and uterus.
Journal of molecular histology 2004;35(4):363-75.
2003: Barbara D Abbott; Tien-Min Lin; Nathan T Rasmussen; Ralph M Albrecht; Judith E Schmid; Richard E Peterson
Lack of expression of EGF and TGF-alpha in the fetal mouse alters formation of prostatic epithelial buds and influences the response to TCDD.
Toxicological sciences : an official journal of the Society of Toxicology 2003;76(2):427-36.
2003: John M Rogers; Barbara D Abbott
Screening for developmental toxicity of tobacco smoke constituents.
Toxicological sciences : an official journal of the Society of Toxicology 2003;75(2):227-8.
2003: Barbara D Abbott
Organ culture of midfacial tissue and secondary palate.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2003;Chapter 13():Unit13.6.
2003: Barbara D Abbott; Angela R Buckalew; Michael J DeVito; David Ross; P Lamont Bryant; Judith E Schmid
EGF and TGF-alpha expression influence the developmental toxicity of TCDD: dose response and AhR phenotype in EGF, TGF-alpha, and EGF + TGF-alpha knockout mice.
Toxicological sciences : an official journal of the Society of Toxicology 2003;71(1):84-95.
2002: Christopher H Hurst; Barbara D Abbott; Judith E Schmid; Linda S Birnbaum
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) disrupts early morphogenetic events that form the lower reproductive tract in female rat fetuses.
Toxicological sciences : an official journal of the Society of Toxicology 2002;65(1):87-98.
2001: JA Pitt; L Feng; Barbara D Abbott; J Schmid; R E Batt; T G Costich; Stephen Thomas Koury; Diane P Bofinger
Expression of AhR and ARNT mRNA in cultured human endometrial explants exposed to TCDD.
Toxicological sciences : an official journal of the Society of Toxicology 2001;62(2):289-98.
2001: P Lamont Bryant; Judith E Schmid; Suzanne E Fenton; Angela R Buckalew; Barbara D Abbott
Teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the expression of EGF and/or TGF-alpha.
Toxicological sciences : an official journal of the Society of Toxicology 2001;62(1):103-14.
2001: P Lamont Bryant; Lola M Reid; Judith E Schmid; Angela R Buckalew; Barbara D Abbott
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on fetal mouse urinary tract epithelium in vitro.
Toxicology 2001;162(1):23-34.
2000: Louise G Parks; Joseph Ostby; Christy Lambright; Barbara D Abbott; Gary R Klinefelter; N J Barlow; L Earl Gray
The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat.
Toxicological sciences : an official journal of the Society of Toxicology 2000;58(2):339-49.
2000: Barbara D Abbott; Angela R Buckalew
Placental defects in ARNT-knockout conceptus correlate with localized decreases in VEGF-R2, Ang-1, and Tie-2.
Developmental dynamics : an official publication of the American Association of Anatomists 2000;219(4):526-38.
2000: JA Pitt; Angela R Buckalew; D E House; Barbara D Abbott
Adrenocorticotropin (ACTH) and corticosterone secretion by perifused pituitary and adrenal glands from rodents exposed to 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD).
Toxicology 2000;151(1-3):25-35.
2000: B Ghosh; Carmen R Wood; GA Held; Barbara D Abbott; Christopher Lau
Glucocorticoid receptor regulation in the rat embryo: a potential site for developmental toxicity?
Toxicology and applied pharmacology 2000;164(2):221-9.
2000: GA Held; Barbara D Abbott
Palatal dysmorphogenesis. Quantitative RT-PCR.
Methods in molecular biology (Clifton, N.J.) 2000;136():203-17.
2000: Barbara D Abbott
Palatal dysmorphogenesis. Palate organ culture.
Methods in molecular biology (Clifton, N.J.) 2000;136():195-201.
1999: Barbara D Abbott; Judith E Schmid; JA Pitt; Angela R Buckalew; Carmen R Wood; GA Held; J J Diliberto
Adverse reproductive outcomes in the transgenic Ah receptor-deficient mouse.
Toxicology and applied pharmacology 1999;155(1):62-70.
1999: J M Peters; Michael G Narotsky; Guillermo Elizondo; Pedro Fernandez-Salguero; Frank J Gonzalez; Barbara D Abbott
Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice.
Toxicological sciences : an official journal of the Society of Toxicology 1999;47(1):86-92.
1999: Barbara D Abbott; Judith E Schmid; J G Brown; Carmen R Wood; R D White; Angela R Buckalew; GA Held
RT-PCR quantification of AHR, ARNT, GR, and CYP1A1 mRNA in craniofacial tissues of embryonic mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone.
Toxicological sciences : an official journal of the Society of Toxicology 1999;47(1):76-85.
1999: Barbara D Abbott; GA Held; Carmen R Wood; Angela R Buckalew; J G Brown; J Schmid
AhR, ARNT, and CYP1A1 mRNA quantitation in cultured human embryonic palates exposed to TCDD and comparison with mouse palate in vivo and in culture.
Toxicological sciences : an official journal of the Society of Toxicology 1999;47(1):62-75.
1998: Christopher H Hurst; Barbara D Abbott; Michael J DeVito; Linda S Birnbaum
2,3,7,8-Tetrachlorodibenzo-p-dioxin in pregnant Long Evans rats: disposition to maternal and embryo/fetal tissues.
Toxicological sciences : an official journal of the Society of Toxicology 1998;45(2):129-36.
1998: Barbara D Abbott; M R Probst; G H Perdew; Angela R Buckalew
AH receptor, ARNT, glucocorticoid receptor, EGF receptor, EGF, TGF alpha, TGF beta 1, TGF beta 2, and TGF beta 3 expression in human embryonic palate, and effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
Teratology 1998;58(2):30-43.
1997: P Lamont Bryant; G C Clark; M R Probst; Barbara D Abbott
Effects of TCDD on Ah receptor, ARNT, EGF, and TGF-alpha expression in embryonic mouse urinary tract.
Teratology 1997;55(5):326-37.
1996: Barbara D Abbott; L S Birnbaum; Janet J Diliberto
Rapid distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) to embryonic tissues in C57BL/6N mice and correlation with palatal uptake in vitro.
Toxicology and applied pharmacology 1996;141(1):256-63.
1995: Barbara D Abbott; M R Probst
Developmental expression of two members of a new class of transcription factors: II. Expression of aryl hydrocarbon receptor nuclear translocator in the C57BL/6N mouse embryo.
Developmental dynamics : an official publication of the American Association of Anatomists 1995;204(2):144-55.
1995: Barbara D Abbott; L S Birnbaum; G H Perdew
Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo.
Developmental dynamics : an official publication of the American Association of Anatomists 1995;204(2):133-43.
1995: Barbara D Abbott; M Ebron-McCoy; JE Andrews
Cell death in rat and mouse embryos exposed to methanol in whole embryo culture.
Toxicology 1995;97(1-3):159-71.
1994: D L Shuey; Angela R Buckalew; T S Wilke; John M Rogers; Barbara D Abbott
Early events following maternal exposure to 5-fluorouracil lead to dysmorphology in cultured embryonic tissues.
Teratology 1994;50(6):379-86.
1994: Barbara D Abbott; M R Probst; G H Perdew
Immunohistochemical double-staining for Ah receptor and ARNT in human embryonic palatal shelves.
Teratology 1994;50(5):361-6.
1994: Barbara D Abbott; G H Perdew; Angela R Buckalew; L S Birnbaum
Interactive regulation of Ah and glucocorticoid receptors in the synergistic induction of cleft palate by 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone.
Toxicology and applied pharmacology 1994;128(1):138-50.
1994: Barbara D Abbott; G H Perdew; L S Birnbaum
Ah receptor in embryonic mouse palate and effects of TCDD on receptor expression.
Toxicology and applied pharmacology 1994;126(1):16-25.
1994: Barbara D Abbott; F M McNabb; C Lau
Glucocorticoid receptor expression during the development of the embryonic mouse secondary palate.
Journal of craniofacial genetics and developmental biology 1994;14(2):87-96.
1994: Barbara D Abbott; T R Logsdon; T S Wilke
Effects of methanol on embryonic mouse palate in serum-free organ culture.
Teratology 1994;49(2):122-34.
1993: Barbara D Abbott; Christopher Lau; Angela R Buckalew; T R Logsdon; W Setzer; Robert M Zucker; K H Elstein; Robert Kavlock
Effects of 5-fluorouracil on embryonic rat palate in vitro: fusion in the absence of proliferation.
Teratology 1993;47(6):541-54.
1992: Barbara D Abbott; Angela R Buckalew
Embryonic palatal responses to teratogens in serum-free organ culture.
Teratology 1992;45(4):369-82.
1992: Barbara D Abbott; M W Harris; L S Birnbaum
Comparisons of the effects of TCDD and hydrocortisone on growth factor expression provide insight into their interaction in the embryonic mouse palate.
Teratology 1992;45(1):35-53.
1991: Barbara D Abbott; R M Pratt
Retinoic acid alters epithelial differentiation during palatogenesis.
Journal of craniofacial genetics and developmental biology 1991;11(4):315-25.
1991: Barbara D Abbott; Linda S Birnbaum
TCDD exposure of human embryonic palatal shelves in organ culture alters the differentiation of medial epithelial cells.
Teratology 1991;43(2):119-32.
1990: S J Stohs; Barbara D Abbott; F H Lin; Linda S Birnbaum
Induction of ethoxyresorufin-O-deethylase and inhibition of glucocorticoid receptor binding in skin and liver of haired and hairless HRS/J mice by topically applied 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Toxicology 1990;65(1-2):123-36.
1990: Barbara D Abbott; Linda S Birnbaum
TCDD-induced altered expression of growth factors may have a role in producing cleft palate and enhancing the incidence of clefts after coadministration of retinoic acid and TCDD.
Toxicology and applied pharmacology 1990;106(3):418-32.
1990: L A Couture; Barbara D Abbott; Linda S Birnbaum
A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances toward understanding the mechanism.
Teratology 1990;42(6):619-27.
1990: Barbara D Abbott; Linda S Birnbaum
Retinoic acid-induced alterations in the expression of growth factors in embryonic mouse palatal shelves.
Teratology 1990;42(6):597-610.
1990: Barbara D Abbott; Linda S Birnbaum
Rat embryonic palatal shelves respond to TCDD in organ culture.
Toxicology and applied pharmacology 1990;103(3):441-51.
1990: Barbara D Abbott; L G Hill; Linda S Birnbaum
Processes involved in retinoic acid production of small embryonic palatal shelves and limb defects.
Teratology 1990;41(3):299-310.
1990: Barbara D Abbott; Linda S Birnbaum
Effects of TCDD on embryonic ureteric epithelial EGF receptor expression and cell proliferation.
Teratology 1990;41(1):71-84.
1989: Barbara D Abbott; M W Harris; Linda S Birnbaum
Etiology of retinoic acid-induced cleft palate varies with the embryonic stage.
Teratology 1989;40(6):533-53.
1989: Barbara D Abbott; Janet J Diliberto; Linda S Birnbaum
2,3,7,8-Tetrachlorodibenzo-p-dioxin alters embryonic palatal medial epithelial cell differentiation in vitro.
Toxicology and applied pharmacology 1989;100(1):119-31.
1989: Barbara D Abbott; Linda S Birnbaum
Cellular alterations and enhanced induction of cleft palate after coadministration of retinoic acid and TCDD.
Toxicology and applied pharmacology 1989;99(2):287-301.
1989: Barbara D Abbott; Linda S Birnbaum
TCDD alters medial epithelial cell differentiation during palatogenesis.
Toxicology and applied pharmacology 1989;99(2):276-86.
1988: Barbara D Abbott; R M Pratt
EGF receptor expression in the developing tooth is altered by exogenous retinoic acid and EGF.
Developmental biology 1988;128(2):300-4.
1988: Barbara D Abbott; R M Pratt
Influence of retinoids and EGF on growth of embryonic mouse palatal epithelia in culture.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1988;24(4):343-52.
1988: Barbara D Abbott; E D Adamson; R M Pratt
Retinoic acid alters EGF receptor expression during palatogenesis.
Development (Cambridge, England) 1988;102(4):853-67.
1988: Eugenia H Goulding; Anton M Jetten; Barbara D Abbott; R M Pratt
Teratogenicity of benzoic acid derivatives of retinoic acid in cultured mouse embryos.
Reproductive toxicology (Elmsford, N.Y.) 1988;2(2):91-8.
1987: Barbara D Abbott; K S Morgan; L S Birnbaum; R M Pratt
TCDD alters the extracellular matrix and basal lamina of the fetal mouse kidney.
Teratology 1987;35(3):335-44.
1987: Barbara D Abbott; L S Birnbaum; R M Pratt
TCDD-induced hyperplasia of the ureteral epithelium produces hydronephrosis in murine fetuses.
Teratology 1987;35(3):329-34.
1987: Barbara D Abbott; R M Pratt
Human embryonic palatal epithelial differentiation is altered by retinoic acid and epidermal growth factor in organ culture.
Journal of craniofacial genetics and developmental biology 1987;7(3):241-65.
1987: Barbara D Abbott; R M Pratt
Retinoids and epidermal growth factor alter embryonic mouse palatal epithelial and mesenchymal cell differentiation in organ culture.
Journal of craniofacial genetics and developmental biology 1987;7(3):219-40.
1987: R M Pratt; Eugenia H Goulding; Barbara D Abbott
Retinoic acid inhibits migration of cranial neural crest cells in the cultured mouse embryo.
Journal of craniofacial genetics and developmental biology 1987;7(3):205-17.