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Per-Olof Berggren

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Chemicals & Drugs

Living Beings

Physiology

Exocytosis

Concepts & Ideas

Disorders

Insulinoma

Procedures

Patch-Clamp Techniques

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Co-Publications
Name
37
Larsson, Olof
32
Leibiger, Ingo
30
Zaitsev, Sergei
29
Efendic, Suad
27
Leibiger, Barbara
27
Rorsman, Patrik
22
Yang, Shao-Nian
20
Efanov, Alexander
19
Bokvist, Krister
18
Bertorello, Alejandro
18
Gromada, Jesper
15
Juntti-Berggren, Lisa
15
Köhler, Martin
14
Bränström, Robert
13
Corkey, Barbara

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Publications

TOP 3
Zaitseva Irina I; Hultcrantz Monica; Sharoyko Vladimir; Flodström-Tullberg Malin; Zaitsev Sergei V; Berggren Per-Olof
Suppressor of cytokine signaling-1 inhibits caspase activation and protects from cytokine-induced beta cell death.
Holmberg Rebecka; Klitz William; Blixt Martin; Berggren Per-Olof; Juntti-Berggren Lisa; Niklasson Bo
Antiviral treatments reduce severity of diabetes in Ljungan virus-infected CD-1 mice and delay onset in diabetes-prone BB rats.
Margolles-Clark Emilio; Jacques-Silva M Caroline; Ganesan Lakshmi; Umland Oliver; Kenyon Norma S; Ricordi Camillo; Berggren Per-Olof; Buchwald Peter
Suramin inhibits the CD40-CD154 costimulatory interaction: a possible mechanism for immunosuppressive effects.

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All Publications

2009: Zaitseva Irina I; Hultcrantz Monica; Sharoyko Vladimir; Flodström-Tullberg Malin; Zaitsev Sergei V; Berggren Per-Olof
Suppressor of cytokine signaling-1 inhibits caspase activation and protects from cytokine-induced beta cell death.
Cellular and molecular life sciences : CMLS 2009;66(23):3787-95.
2009: Holmberg Rebecka; Klitz William; Blixt Martin; Berggren Per-Olof; Juntti-Berggren Lisa; Niklasson Bo
Antiviral treatments reduce severity of diabetes in Ljungan virus-infected CD-1 mice and delay onset in diabetes-prone BB rats.
Microbiology and immunology 2009;53(10):567-72.
2009: Margolles-Clark Emilio; Jacques-Silva M Caroline; Ganesan Lakshmi; Umland Oliver; Kenyon Norma S; Ricordi Camillo; Berggren Per-Olof; Buchwald Peter
Suramin inhibits the CD40-CD154 costimulatory interaction: a possible mechanism for immunosuppressive effects.
Biochemical pharmacology 2009;77(7):1236-45.
2009: Barker Christopher J; Illies Christopher; Fiume Roberta; Gaboardi Gian Carlo; Yu Jia; Berggren Per-Olof
Diphosphoinositol pentakisphosphate as a novel mediator of insulin exocytosis.
Advances in enzyme regulation 2009;49(1):168-73.
2009: Lau Joey; Kampf Caroline; Mattsson Göran; Nyqvist Daniel; Köhler Martin; Berggren Per-Olof; Carlsson Per-Ola
Beneficial role of pancreatic microenvironment for angiogenesis in transplanted pancreatic islets.
Cell transplantation 2009;18(1):23-30.
2009: Håkanson Bengt S; Berggren Per; Granqvist Staffan; Ljungqvist Olle; Thorell Anders
Comparison of wireless 48-h (Bravo) versus traditional ambulatory 24-h esophageal pH monitoring.
Scandinavian journal of gastroenterology 2009;44(3):276-83.
2008: Johansson Jenny U; Ericsson Jesper; Janson Juliette; Beraki Simret; Stanic Davor; Mandic Slavena A; Wikström Martin A; Hökfelt Tomas; Ogren Sven Ove; Rozell Björn; Berggren Per-Olof; Bark Christina
An ancient duplication of exon 5 in the Snap25 gene is required for complex neuronal development/function.
PLoS genetics 2008;4(11):e1000278.
2008: Cabrera Over; Jacques-Silva M Caroline; Speier Stephan; Yang Shao-Nian; Köhler Martin; Fachado Alberto; Vieira Elaine; Zierath Juleen R; Kibbey Richard; Berman Dora M; Kenyon Norma S; Ricordi Camillo; Caicedo Alejandro; Berggren Per-Olof
Glutamate is a positive autocrine signal for glucagon release.
Cell metabolism 2008;7(6):545-54.
2008: Bertolino Philippe; Holmberg Rebecka; Reissmann Eva; Andersson Olov; Berggren Per-Olof; Ibáñez Carlos F
Activin B receptor ALK7 is a negative regulator of pancreatic beta-cell function.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(20):7246-51.
2008: Shafqat Jawed; Ishrat Moin; Jägerbrink Theres; Sillard Rannar; Mäeorg Uno; Efendic Suad; Berggren Per-Olof; Zaitsev Sergei V; Jörnvall Hans
Proteins in the insulin-secreting cell line MIN6 bind the imidazoline compound BL11282.
FEBS letters 2008;582(11):1613-7.
2008: Berggren P-O; Brismar K
Professor Rolf Luft, 1914--2007.
Diabetologia 2008;51(5):697-9.
2008: Speier Stephan; Nyqvist Daniel; Cabrera Over; Yu Jia; Molano R Damaris; Pileggi Antonello; Moede Tilo; Köhler Martin; Wilbertz Johannes; Leibiger Barbara; Ricordi Camillo; Leibiger Ingo B; Caicedo Alejandro; Berggren Per-Olof
Noninvasive in vivo imaging of pancreatic islet cell biology.
Nature medicine 2008;14(5):574-8.
2008: Zaitseva I I; Størling J; Mandrup-Poulsen T; Berggren P-O; Zaitsev S V
The imidazoline RX871024 induces death of proliferating insulin-secreting cells by activation of c-jun N-terminal kinase.
Cellular and molecular life sciences : CMLS 2008;65(7-8):1248-55.
2008: Speier Stephan; Nyqvist Daniel; Köhler Martin; Caicedo Alejandro; Leibiger Ingo B; Berggren Per-Olof
Noninvasive high-resolution in vivo imaging of cell biology in the anterior chamber of the mouse eye.
Nature protocols 2008;3(8):1278-86.
2008: Paulsson Johan F; Schultz Sebastian W; Köhler Martin; Leibiger Ingo; Berggren Per-Olof; Westermark Gunilla T
Real-time monitoring of apoptosis by caspase-3-like protease induced FRET reduction triggered by amyloid aggregation.
Experimental diabetes research 2008;2008():865850.
2008: Leibiger Ingo B; Leibiger Barbara; Berggren Per-Olof
Insulin signaling in the pancreatic beta-cell.
Annual review of nutrition 2008;28():233-51.
2008: Cabrera Over; Jacques-Silva M Caroline; Berman Dora M; Fachado Alberto; Echeverri Felipe; Poo Ramon; Khan Aisha; Kenyon Norma S; Ricordi Camillo; Berggren Per-Olof; Caicedo Alejandro
Automated, high-throughput assays for evaluation of human pancreatic islet function.
Cell transplantation 2008;16(10):1039-48.
2008: Berggren Per-Olof; Barker Christopher J
A key role for phosphorylated inositol compounds in pancreatic beta-cell stimulus-secretion coupling.
Advances in enzyme regulation 2008;48():276-94.
2007: Dekki N; Nilsson R; Norgren S; Rössner S M; Appelskog I; Marcus C; Simell O; Pugliese A; Alejandro R; Ricordi C; Berggren P O; Juntti-Berggren L
Type 1 diabetic serum interferes with pancreatic beta-cell Ca2+-handling.
Bioscience reports 2007;27(6):321-6.
2007: Illies Christopher; Gromada Jesper; Fiume Roberta; Leibiger Barbara; Yu Jia; Juhl Kirstine; Yang Shao-Nian; Barma Deb K; Falck John R; Saiardi Adolfo; Barker Christopher J; Berggren Per-Olof
Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic beta cells.
Science (New York, N.Y.) 2007;318(5854):1299-302.
2007: Sharoyko V V; Zaitseva I I; Leibiger B; Efendic S; Berggren P O; Zaitsev S V
Arachidonic acid signaling is involved in the mechanism of imidazoline-induced KATP channel-independent stimulation of insulin secretion.
Cellular and molecular life sciences : CMLS 2007;64(22):2985-93.
2007: Yu Jia; Berggren Per-Olof; Barker Christopher J
An autocrine insulin feedback loop maintains pancreatic beta-cell 3-phosphorylated inositol lipids.
Molecular endocrinology (Baltimore, Md.) 2007;21(11):2775-84.
2007: Yang Shao-Nian; Wenna Nancy Dekki; Yu Jia; Yang Guang; Qiu Hua; Yu Lina; Juntti-Berggren Lisa; Köhler Martin; Berggren Per-Olof
Glucose recruits K(ATP) channels via non-insulin-containing dense-core granules.
Cell metabolism 2007;6(3):217-28.
2007: Richard Ann-Marie T; Webb Dominic-Luc; Goodman Jessie M; Schultz Vera; Flanagan John N; Getty-Kaushik Lisa; Deeney Jude T; Yaney Gordon C; Dunaway George A; Berggren Per-Olof; Tornheim Keith
Tissue-dependent loss of phosphofructokinase-M in mice with interrupted activity of the distal promoter: impairment in insulin secretion.
American journal of physiology. Endocrinology and metabolism 2007;293(3):E794-801.
2007: Berman Dora M; Cabrera Over; Kenyon Norman M; Miller Joshua; Tam Susan H; Khandekar Vrinda S; Picha Kristen M; Soderman Avery R; Jordan Robert E; Bugelski Peter J; Horninger Denison; Lark Michael; Davis Janet E; Alejandro Rodolfo; Berggren Per-Olof; Zimmerman Mark; O'Neil John J; Ricordi Camillo; Kenyon Norma S
Interference with tissue factor prolongs intrahepatic islet allograft survival in a nonhuman primate marginal mass model.
Transplantation 2007;84(3):308-15.
2007: Deeney Jude T; Bränström Robert; Corkey Barbara E; Larsson Olof; Berggren Per-Olof
3H-serotonin as a marker of oscillatory insulin secretion in clonal beta-cells (INS-1).
FEBS letters 2007;581(21):4080-4.
2007: Bränström R; Leibiger I B; Leibiger B; Klement G; Nilsson J; Arhem P; Aspinwall C A; Corkey B E; Larsson O; Berggren P-O
Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif.
Diabetologia 2007;50(8):1670-7.
2007: Niklasson Bo; Hultman T; Kallies R; Niedrig M; Nilsson R; Berggren P-O; Juntti-Berggren L; Efendic S; Lernmark A; Klitz W
The BioBreeding rat diabetes model is infected with Ljungan virus.
Diabetologia 2007;50(7):1559-60.
2007: Lau Joey; Mattsson Göran; Carlsson Carina; Nyqvist Daniel; Köhler Martin; Berggren Per-Olof; Jansson Leif; Carlsson Per-Ola
Implantation site-dependent dysfunction of transplanted pancreatic islets.
Diabetes 2007;56(6):1544-50.
2007: Jägerbrink T; Lexander H; Palmberg C; Shafqat J; Sharoyko V; Berggren P-O; Efendic S; Zaitsev S; Jörnvall H
Differential protein expression in pancreatic islets after treatment with an imidazoline compound.
Cellular and molecular life sciences : CMLS 2007;64(10):1310-6.
2007: Uhles Sabine; Moede Tilo; Leibiger Barbara; Berggren Per-Olof; Leibiger Ingo B
Selective gene activation by spatial segregation of insulin receptor B signaling.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(7):1609-21.
2007: Zhang Quan; Bengtsson Martin; Partridge Chris; Salehi Albert; Braun Matthias; Cox Roger; Eliasson Lena; Johnson Paul R V; Renström Erik; Schneider Toni; Berggren Per-Olof; Göpel Sven; Ashcroft Frances M; Rorsman Patrik
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion.
Nature cell biology 2007;9(4):453-60.
2007: von Seth Erik; Nyqvist Daniel; Andersson Arne; Carlsson Per-Ola; Köhler Martin; Mattsson Göran; Nordin Astrid; Berggren Per-Olof; Jansson Leif
Distribution of intraportally implanted microspheres and fluorescent islets in mice.
Cell transplantation 2007;16(6):621-7.
2006: Miettinen Päivi J; Ustinov Jarkko; Ormio Päivi; Gao Ru; Palgi Jaan; Hakonen Elina; Juntti-Berggren Lisa; Berggren Per-Olof; Otonkoski Timo
Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth.
Diabetes 2006;55(12):3299-308.
2006: Henriksson M; Johansson J; Moede T; Leibiger I; Shafqat J; Berggren P-O; Jörnvall H
Proinsulin C-peptide and insulin: Limited pattern similarities of interest in inter-peptide interactions but no C-peptide effect on insulin and IGF-1 receptor signaling.
Cellular and molecular life sciences : CMLS 2006;63(24):3055-60.
2006: Yang Shao-Nian; Berggren Per-Olof
The role of voltage-gated calcium channels in pancreatic beta-cell physiology and pathophysiology.
Endocrine reviews 2006;27(6):621-76.
2006: Zaitseva Irina I; Sharoyko Vladimir; Størling Joachim; Efendic Suad; Guerin Christopher; Mandrup-Poulsen Thomas; Nicotera Pierluigi; Berggren Per-Olof; Zaitsev Sergei V
RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines.
Biochemical and biophysical research communications 2006;347(4):1121-8.
2006: Berggren Per-Olof; Leibiger Ingo B
Novel aspects on signal-transduction in the pancreatic beta-cell.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2006;16 Suppl 1():S7-10.
2006: Zhang Wei; Lilja Lena; Mandic Slavena A; Gromada Jesper; Smidt Kamille; Janson Juliette; Takai Yoshimi; Bark Christina; Berggren Per-Olof; Meister Björn
Tomosyn is expressed in beta-cells and negatively regulates insulin exocytosis.
Diabetes 2006;55(3):574-81.
2006: Cabrera Over; Berman Dora M; Kenyon Norma S; Ricordi Camillo; Berggren Per-Olof; Caicedo Alejandro
The unique cytoarchitecture of human pancreatic islets has implications for islet cell function.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2334-9.
2006: Leibiger Ingo B; Berggren Per-Olof
Sirt1: a metabolic master switch that modulates lifespan.
Nature medicine 2006;12(1):34-6; discussion 36.
2005: Sharoyko Vladimir V; Zaitseva Irina I; Varsanyi Mark; Portwood Neil; Leibiger Barbara; Leibiger Ingo; Berggren Per-Olof; Efendic Suad; Zaitsev Sergei V
Monomeric G-protein, Rhes, is not an imidazoline-regulated protein in pancreatic beta-cells.
Biochemical and biophysical research communications 2005;338(3):1455-9.
2005: Refai Essam; Dekki Nancy; Yang Shao-Nian; Imreh Gabriela; Cabrera Over; Yu Lina; Yang Guang; Norgren Svante; Rössner Sophia M; Inverardi Luca; Ricordi Camillo; Olivecrona Gunilla; Andersson Mats; Jörnvall Hans; Berggren Per-Olof; Juntti-Berggren Lisa
Transthyretin constitutes a functional component in pancreatic beta-cell stimulus-secretion coupling.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(47):17020-5.
2005: Leibiger Ingo B; Berggren Per-Olof
A SIRTain role in pancreatic beta cell function.
Cell metabolism 2005;2(2):80-2.
2005: Nyqvist Daniel; Mattsson Göran; Köhler Martin; Lev-Ram Varda; Andersson Arne; Carlsson Per-Ola; Nordin Astrid; Berggren Per-Olof; Jansson Leif
Pancreatic islet function in a transgenic mouse expressing fluorescent protein.
The Journal of endocrinology 2005;186(2):333-41.
2005: Nyqvist Daniel; Köhler Martin; Wahlstedt Helene; Berggren Per-Olof
Donor islet endothelial cells participate in formation of functional vessels within pancreatic islet grafts.
Diabetes 2005;54(8):2287-93.
2005: Johansson Jenny U; Lilja Lena; Chen Xiao-Liang; Higashida Haruhiro; Meister Björn; Noda Mami; Zhong Zhen-Guo; Yokoyama Shigeru; Berggren Per-Olof; Bark Christina
Cyclin-dependent kinase 5 activators p35 and p39 facilitate formation of functional synapses.
Brain research. Molecular brain research 2005;138(2):215-27.
2005: Gromada Jesper; Bark Christina; Smidt Kamille; Efanov Alexander M; Janson Juliette; Mandic Slavena A; Webb Dominic-Luc; Zhang Wei; Meister Björn; Jeromin Andreas; Berggren Per-Olof
Neuronal calcium sensor-1 potentiates glucose-dependent exocytosis in pancreatic beta cells through activation of phosphatidylinositol 4-kinase beta.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(29):10303-8.
2005: Ichii Hirohito; Inverardi Luca; Pileggi Antonello; Molano R Damaris; Cabrera Over; Caicedo Alejandro; Messinger Shari; Kuroda Yoshikazu; Berggren Per-Olof; Ricordi Camillo
A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(7):1635-45.
2005: Størling Joachim; Zaitsev Sergei V; Kapelioukh Iouri L; Karlsen Allan E; Billestrup Nils; Berggren Per-Olof; Mandrup-Poulsen Thomas
Calcium has a permissive role in interleukin-1beta-induced c-jun N-terminal kinase activation in insulin-secreting cells.
Endocrinology 2005;146(7):3026-36.
2005: Lilja Lena; Meister Björn; Berggren Per-Olof; Bark Christina
DARPP-32 and inhibitor-1 are expressed in pancreatic beta-cells.
Biochemical and biophysical research communications 2005;329(2):673-7.
2005: Yang Shao-Nian; Berggren Per-Olof
CaV2.3 channel and PKClambda: new players in insulin secretion.
The Journal of clinical investigation 2005;115(1):16-20.
2005: Yang Shao-Nian; Berggren Per-Olof
Beta-cell CaV channel regulation in physiology and pathophysiology.
American journal of physiology. Endocrinology and metabolism 2005;288(1):E16-28.
2005: Ma Xiaosong; Zhang Yang; Gromada Jesper; Sewing Sabine; Berggren Per-Olof; Buschard Karsten; Salehi Albert; Vikman Jenny; Rorsman Patrik; Eliasson Lena
Glucagon stimulates exocytosis in mouse and rat pancreatic alpha-cells by binding to glucagon receptors.
Molecular endocrinology (Baltimore, Md.) 2005;19(1):198-212.
2004: Gromada Jesper; Ma Xiaosong; Høy Marianne; Bokvist Krister; Salehi Albert; Berggren Per-Olof; Rorsman Patrik
ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells.
Diabetes 2004;53 Suppl 3():S181-9.
2004: Berggren Per-Olof; Yang Shao-Nian; Murakami Manabu; Efanov Alexander M; Uhles Sabine; Köhler Martin; Moede Tilo; Fernström Andreas; Appelskog Ioulia B; Aspinwall Craig A; Zaitsev Sergei V; Larsson Olof; de Vargas Lina Moitoso; Fecher-Trost Claudia; Weissgerber Petra; Ludwig Andreas; Leibiger Barbara; Juntti-Berggren Lisa; Barker Christopher J; Gromada Jesper; Freichel Marc; Leibiger Ingo B; Flockerzi Veit
Removal of Ca2+ channel beta3 subunit enhances Ca2+ oscillation frequency and insulin exocytosis.
Cell 2004;119(2):273-84.
2004: Zhang Wei; Lilja Lena; Bark Christina; Berggren Per-Olof; Meister Björn
Mint1, a Munc-18-interacting protein, is expressed in insulin-secreting beta-cells.
Biochemical and biophysical research communications 2004;320(3):717-21.
2004: Juntti-Berggren Lisa; Refai Essam; Appelskog Ioulia; Andersson Mats; Imreh Gabriela; Dekki Nancy; Uhles Sabine; Yu Lina; Griffiths William J; Zaitsev Sergei; Leibiger Ingo; Yang Shao-Nian; Olivecrona Gunilla; Jörnvall Hans; Berggren Per-Olof
Apolipoprotein CIII promotes Ca2+-dependent beta cell death in type 1 diabetes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(27):10090-4.
2004: Lilja Lena; Johansson Jenny Ulrika; Gromada Jesper; Mandic Slavena Andrea; Fried Gabriel; Berggren Per-Olof; Bark Christina
Cyclin-dependent kinase 5 associated with p39 promotes Munc18-1 phosphorylation and Ca(2+)-dependent exocytosis.
The Journal of biological chemistry 2004;279(28):29534-41.
2004: Zhang Qimin; Köhler Martin; Yang Shao-Nian; Zhang Fan; Larsson Olof; Berggren Per-Olof
Growth hormone promotes Ca(2+)-induced Ca2+ release in insulin-secreting cells by ryanodine receptor tyrosine phosphorylation.
Molecular endocrinology (Baltimore, Md.) 2004;18(7):1658-69.
2004: Bränström R; Aspinwall C A; Välimäki S; Ostensson C-G; Tibell A; Eckhard M; Brandhorst H; Corkey B E; Berggren P-O; Larsson O
Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes.
Diabetologia 2004;47(2):277-83.
2003: Uhles Sabine; Moede Tilo; Leibiger Barbara; Berggren Per-Olof; Leibiger Ingo B
Isoform-specific insulin receptor signaling involves different plasma membrane domains.
The Journal of cell biology 2003;163(6):1327-37.
2003: Köhler Martin; Zaitsev Sergei V; Zaitseva Irina I; Leibiger Barbara; Leibiger Ingo B; Turunen Mikael; Kapelioukh Iouri L; Bakkman Linda; Appelskog Ioulia B; de Monvel Jacques Boutet; Imreh Gabriela; Berggren Per-Olof
On-line monitoring of apoptosis in insulin-secreting cells.
Diabetes 2003;52(12):2943-50.
2003: Yu Jia; Leibiger Barbara; Yang Shao-Nian; Caffery James J; Shears Stephen B; Leibiger Ingo B; Barker Christopher J; Berggren Per-Olof
Cytosolic multiple inositol polyphosphate phosphatase in the regulation of cytoplasmic free Ca2+ concentration.
The Journal of biological chemistry 2003;278(47):46210-8.
2003: Mendez Carlos F; Leibiger Ingo B; Leibiger Barbara; Høy Marianne; Gromada Jesper; Berggren Per-Olof; Bertorello Alejandro M
Rapid association of protein kinase C-epsilon with insulin granules is essential for insulin exocytosis.
The Journal of biological chemistry 2003;278(45):44753-7.
2003: Kamp Frits; Kizilbash Nadeem; Corkey Barbara E; Berggren Per-Olof; Hamilton James A
Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism.
Diabetes 2003;52(10):2526-31.
2003: Juntti-Berggren Lisa; Webb Dominic-Luc; Arkhammar Per O G; Schultz Vera; Schweda Elke K H; Tornheim Keith; Berggren Per-Olof
Dihydroxyacetone-induced oscillations in cytoplasmic free Ca2+ and the ATP/ADP ratio in pancreatic beta-cells at substimulatory glucose.
The Journal of biological chemistry 2003;278(42):40710-6.
2003: Høy Marianne; Berggren Per-Olof; Gromada Jesper
Involvement of protein kinase C-epsilon in inositol hexakisphosphate-induced exocytosis in mouse pancreatic beta-cells.
The Journal of biological chemistry 2003;278(37):35168-71.
2003: Lehtihet Mikael; Welsh Nils; Berggren Per-Olof; Cook George A; Sjoholm Ake
Glibenclamide inhibits islet carnitine palmitoyltransferase 1 activity, leading to PKC-dependent insulin exocytosis.
American journal of physiology. Endocrinology and metabolism 2003;285(2):E438-46.
2003: Yoon J Cliff; Xu Gang; Deeney Jude T; Yang Shao-Nian; Rhee James; Puigserver Pere; Levens Adah R; Yang Ruojing; Zhang Chen-Yu; Lowell Bradford B; Berggren Per-Olof; Newgard Christopher B; Bonner-Weir Susan; Weir Gordon; Spiegelman Bruce M
Suppression of beta cell energy metabolism and insulin release by PGC-1alpha.
Developmental cell 2003;5(1):73-83.
2003: Olsen Hervør L; Hoy Marianne; Zhang Wei; Bertorello Alejandro M; Bokvist Krister; Capito Kirsten; Efanov Alexander M; Meister Björn; Thams Peter; Yang Shao-Nian; Rorsman Patrik; Berggren Per-Olof; Gromada Jesper
Phosphatidylinositol 4-kinase serves as a metabolic sensor and regulates priming of secretory granules in pancreatic beta cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5187-92.
2003: Eliasson Lena; Ma Xiaosong; Renström Erik; Barg Sebastian; Berggren Per-Olof; Galvanovskis Juris; Gromada Jesper; Jing Xingjun; Lundquist Ingmar; Salehi Albert; Sewing Sabine; Rorsman Patrik
SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells.
The Journal of general physiology 2003;121(3):181-97.
2002: Efendic Suad; Efanov Alexander M; Berggren Per-Olof; Zaitsev Sergei V
Two generations of insulinotropic imidazoline compounds.
Diabetes 2002;51 Suppl 3():S448-54.
2002: Leibiger Ingo B; Leibiger Barbara; Berggren Per-Olof
Insulin feedback action on pancreatic beta-cell function.
FEBS letters 2002;532(1-2):1-6.
2002: Sjöholm Ake; Lehtihet Mikael; Efanov Alexandre M; Zaitsev Sergei V; Berggren Per-Olof; Honkanen Richard E
Glucose metabolites inhibit protein phosphatases and directly promote insulin exocytosis in pancreatic beta-cells.
Endocrinology 2002;143(12):4592-8.
2002: Barker Christopher J; Leibiger Ingo B; Leibiger Barbara; Berggren Per-Olof
Phosphorylated inositol compounds in beta -cell stimulus-response coupling.
American journal of physiology. Endocrinology and metabolism 2002;283(6):E1113-22.
2002: Høy Marianne; Maechler Pierre; Efanov Alexander M; Wollheim Claes B; Berggren Per Olof; Gromada Jesper
Increase in cellular glutamate levels stimulates exocytosis in pancreatic beta-cells.
FEBS letters 2002;531(2):199-203.
2002: Efendiev Riad; Yudowski Guillermo A; Zwiller Jean; Leibiger Barbara; Katz Adrian I; Berggren Per-Olof; Pedemonte Carlos H; Leibiger Ingo B; Bertorello Alejandro M
Relevance of dopamine signals anchoring dynamin-2 to the plasma membrane during Na+,K+-ATPase endocytosis.
The Journal of biological chemistry 2002;277(46):44108-14.
2002: Shiota Chiyo; Larsson Olof; Shelton Kathy D; Shiota Masakazu; Efanov Alexander M; Hoy Marianne; Lindner Jill; Kooptiwut Suwattanee; Juntti-Berggren Lisa; Gromada Jesper; Berggren Per-Olof; Magnuson Mark A
Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose.
The Journal of biological chemistry 2002;277(40):37176-83.
2002: Shafqat J; Juntti-Berggren L; Zhong Z; Ekberg K; Köhler M; Berggren P O; Johansson J; Wahren J; Jörnvall H
Proinsulin C-peptide and its analogues induce intracellular Ca2+ increases in human renal tubular cells.
Cellular and molecular life sciences : CMLS 2002;59(7):1185-9.
2002: Høy Marianne; Efanov Alexander M; Bertorello Alejandro M; Zaitsev Sergei V; Olsen Hervør L; Bokvist Krister; Leibiger Barbara; Leibiger Ingo B; Zwiller Jean; Berggren Per-Olof; Gromada Jesper
Inositol hexakisphosphate promotes dynamin I- mediated endocytosis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6773-7.
2002: Ji Junzhi; Yang Shao-Nian; Huang Xiaohang; Li Xidan; Sheu Laura; Diamant Nicholas; Berggren Per-Olof; Gaisano Herbert Y
Modulation of L-type Ca(2+) channels by distinct domains within SNAP-25.
Diabetes 2002;51(5):1425-36.
2002: Doné Stefania Cotta; Leibiger Ingo B; Efendiev Riad; Katz Adrian I; Leibiger Barbara; Berggren Per-Olof; Pedemonte Carlos H; Bertorello Alejandro M
Tyrosine 537 within the Na+,K+-ATPase alpha-subunit is essential for AP-2 binding and clathrin-dependent endocytosis.
The Journal of biological chemistry 2002;277(19):17108-11.
2002: Leibiger Barbara; Moede T; Uhles S; Berggren P O; Leibiger I B
Short-term regulation of insulin gene transcription.
Biochemical Society transactions 2002;30(2):312-7.
2002: Zhang Wei; Khan Akhtar; Ostenson Claes-Goran; Berggren Per-Olof; Efendic Suad; Meister Björn
Down-regulated expression of exocytotic proteins in pancreatic islets of diabetic GK rats.
Biochemical and biophysical research communications 2002;291(4):1038-44.
2002: Efanov Alexander M; Appelskog Ioulia B; Abdel-Halim Samy M; Khan Akhtar; Bränström Robert; Larsson Olof; Ostenson Claes-Göran; Mest Hans-Juergen; Berggren Per-Olof; Efendic Suad; Zaitsev Sergei V
Insulinotropic activity of the imidazoline derivative RX871024 in the diabetic GK rat.
American journal of physiology. Endocrinology and metabolism 2002;282(1):E117-24.
2001: Liu L; Doné S C; Khoshnoodi J; Bertorello A; Wartiovaara J; Berggren P O; Tryggvason K
Defective nephrin trafficking caused by missense mutations in the NPHS1 gene: insight into the mechanisms of congenital nephrotic syndrome.
Human molecular genetics 2001;10(23):2637-44.
2001: Deeney J T; Köhler M; Kubik K; Brown G; Schultz V; Tornheim K; Corkey B E; Berggren P O
Glucose-induced metabolic oscillations parallel those of Ca(2+) and insulin release in clonal insulin-secreting cells. A multiwell approach to oscillatory cell behavior.
The Journal of biological chemistry 2001;276(40):36946-50.
2001: Kindmark H; Köhler M; Brown G; Bränström R; Larsson O; Berggren P O
Glucose-induced oscillations in cytoplasmic free Ca2+ concentration precede oscillations in mitochondrial membrane potential in the pancreatic beta-cell.
The Journal of biological chemistry 2001;276(37):34530-6.
2001: Lilja L; Yang S N; Webb D L; Juntti-Berggren L; Berggren P O; Bark C
Cyclin-dependent kinase 5 promotes insulin exocytosis.
The Journal of biological chemistry 2001;276(36):34199-205.
2001: Johansen J E; Teixeira V L; Johansson C; Serrão P; Berggren P O; Soares-Da-Silva P; Schalling M; Bertorello A M
Altered dopaminergic transmission in the anorexic anx/anx mouse striatum.
Neuroreport 2001;12(12):2737-41.
2001: Yang S N; Yu J; Mayr G W; Hofmann F; Larsson O; Berggren P O
Inositol hexakisphosphate increases L-type Ca2+ channel activity by stimulation of adenylyl cyclase.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1753-63.
2001: Agrup C; Berggren P O; Bagger-Sjöbäck D
Morphological and functional characteristics of cells cultured from the endolymphatic sac.
Hearing research 2001;157(1-2):43-51.
2001: Efanov A M; Høy M; Bränström R; Zaitsev S V; Magnuson M A; Efendic S; Gromada J; Berggren P O
The imidazoline RX871024 stimulates insulin secretion in pancreatic beta-cells from mice deficient in K(ATP) channel function.
Biochemical and biophysical research communications 2001;284(4):918-22.
2001: Sjöholm A; Berggren P O; Honkanen R E
Effects of second messengers on serine/threonine protein phosphatases in insulin-secreting cells.
Biochemical and biophysical research communications 2001;283(2):364-8.
2001: Chen X L; Zhong Z G; Yokoyama S; Bark C; Meister B; Berggren P O; Roder J; Higashida H; Jeromin A
Overexpression of rat neuronal calcium sensor-1 in rodent NG108-15 cells enhances synapse formation and transmission.
The Journal of physiology 2001;532(Pt 3):649-59.
2001: Efanov A M; Zaitsev S V; Mest H J; Raap A; Appelskog I B; Larsson O; Berggren P O; Efendic S
The novel imidazoline compound BL11282 potentiates glucose-induced insulin secretion in pancreatic beta-cells in the absence of modulation of K(ATP) channel activity.
Diabetes 2001;50(4):797-802.
2001: Leibiger B; Leibiger I B; Moede T; Kemper S; Kulkarni R N; Kahn C R; de Vargas L M; Berggren P O
Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells.
Molecular cell 2001;7(3):559-70.
2001: Efanov A M; Zaitsev S V; Berggren P O; Mest H J; Efendic S
Imidazoline RX871024 raises diacylglycerol levels in rat pancreatic islets.
Biochemical and biophysical research communications 2001;281(5):1070-3.
2001: Lemmens R; Larsson O; Berggren P O; Islam M S
Ca2+-induced Ca2+ release from the endoplasmic reticulum amplifies the Ca2+ signal mediated by activation of voltage-gated L-type Ca2+ channels in pancreatic beta-cells.
The Journal of biological chemistry 2001;276(13):9971-7.
2001: Chandra J; Yang S N; Köhler M; Zaitsev S; Juntti-Berggren L; Berggren P O; Zhivotovsky B; Orrenius S
Effects of serum from patients with type 1 diabetes on primary cerebellar granule cells.
Diabetes 2001;50 Suppl 1():S77-81.
2001: Zaitsev S V; Appelskog I B; Kapelioukh I L; Yang S N; Köhler M; Efendic S; Berggren P O
Imidazoline compounds protect against interleukin 1beta-induced beta-cell apoptosis.
Diabetes 2001;50 Suppl 1():S70-6.
2001: Chandra J; Zhivotovsky B; Zaitsev S; Juntti-Berggren L; Berggren P O; Orrenius S
Role of apoptosis in pancreatic beta-cell death in diabetes.
Diabetes 2001;50 Suppl 1():S44-7.
2001: Moede T; Leibiger B; Berggren P O; Leibiger I B
Online monitoring of stimulus-induced gene expression in pancreatic beta-cells.
Diabetes 2001;50 Suppl 1():S15-9.
2001: Sjöholm A; Arkhammar P; Berggren P O; Andersson A
Polyamines in pancreatic islets of obese-hyperglycemic (ob/ob) mice of different ages.
American journal of physiology. Cell physiology 2001;280(2):C317-23.
2001: Høy M; Bokvist K; Xiao-Gang W; Hansen J; Juhl K; Berggren P O; Buschard K; Gromada J
Phentolamine inhibits exocytosis of glucagon by Gi2 protein-dependent activation of calcineurin in rat pancreatic alpha -cells.
The Journal of biological chemistry 2001;276(2):924-30.
2000: Zhang W; Efanov A; Yang S N; Fried G; Kolare S; Brown H; Zaitsev S; Berggren P O; Meister B
Munc-18 associates with syntaxin and serves as a negative regulator of exocytosis in the pancreatic beta -cell.
The Journal of biological chemistry 2000;275(52):41521-7.
2000: Silva J P; Köhler M; Graff C; Oldfors A; Magnuson M A; Berggren P O; Larsson N G
Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes.
Nature genetics 2000;26(3):336-40.
2000: Ares M P; Pörn-Ares M I; Moses S; Thyberg J; Juntti-Berggren L; Berggren P; Hultgårdh-Nilsson A; Kallin B; Nilsson J
7beta-hydroxycholesterol induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells.
Atherosclerosis 2000;153(1):23-35.
2000: Sjöholm A; Berggren P O; Cooney R V
gamma-tocopherol partially protects insulin-secreting cells against functional inhibition by nitric oxide.
Biochemical and biophysical research communications 2000;277(2):334-40.
2000: Larsson O; Barker C J; Berggren P O
Phosphatidylinositol 4,5-bisphosphate and ATP-sensitive potassium channel regulation: a word of caution.
Diabetes 2000;49(9):1409-12.
2000: Leibiger B; Wahlander K; Berggren P O; Leibiger I B
Glucose-stimulated insulin biosynthesis depends on insulin-stimulated insulin gene transcription.
The Journal of biological chemistry 2000;275(39):30153-6.
2000: Sjöholm A; Zhang Q; Welsh N; Hansson A; Larsson O; Tally M; Berggren P O
Rapid Ca2+ influx and diacylglycerol synthesis in growth hormone-mediated islet beta -cell mitogenesis.
The Journal of biological chemistry 2000;275(28):21033-40.
2000: Yudowski G A; Efendiev R; Pedemonte C H; Katz A I; Berggren P O; Bertorello A M
Phosphoinositide-3 kinase binds to a proline-rich motif in the Na+, K+-ATPase alpha subunit and regulates its trafficking.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6556-61.
2000: Brown H; Meister B; Deeney J; Corkey B E; Yang S N; Larsson O; Rhodes C J; Seino S; Berggren P O; Fried G
Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis.
Diabetes 2000;49(3):383-91.
2000: Deeney J T; Gromada J; Høy M; Olsen H L; Rhodes C J; Prentki M; Berggren P O; Corkey B E
Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells).
The Journal of biological chemistry 2000;275(13):9363-8.
2000: Ogimoto G; Yudowski G A; Barker C J; Köhler M; Katz A I; Féraille E; Pedemonte C H; Berggren P O; Bertorello A M
G protein-coupled receptors regulate Na+,K+-ATPase activity and endocytosis by modulating the recruitment of adaptor protein 2 and clathrin.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3242-7.
2000: Zhuang H; Bhattacharjee A; Hu F; Zhang M; Goswami T; Wang L; Wu S; Berggren P O; Li M
Cloning of a T-type Ca2+ channel isoform in insulin-secreting cells.
Diabetes 2000;49(1):59-64.
1999: Moede T; Leibiger B; Pour H G; Berggren P; Leibiger I B
Identification of a nuclear localization signal, RRMKWKK, in the homeodomain transcription factor PDX-1.
FEBS letters 1999;461(3):229-34.
1999: Barker C J; Berggren P O
Inositol hexakisphosphate and beta-cell stimulus-secretion coupling.
Anticancer research 1999;19(5A):3737-41.
1999: Yang S N; Larsson O; Bränström R; Bertorello A M; Leibiger B; Leibiger I B; Moede T; Köhler M; Meister B; Berggren P O
Syntaxin 1 interacts with the L(D) subtype of voltage-gated Ca(2+) channels in pancreatic beta cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(18):10164-9.
1999: Zaitsev S V; Efanov A M; Raap A; Efanova I B; Schloos J; Steckel-Hamann B; Larsson O; Ostenson C G; Berggren P O; Mest H J; Efendic S
Different modes of action of the imidazoline compound RX871024 in pancreatic beta-cells. Blocking of K+ channels, mobilization of Ca2+ from endoplasmic reticulum, and interaction with exocytotic machinery.
Annals of the New York Academy of Sciences 1999;881():241-52.
1999: Barg S; Renström E; Berggren P O; Bertorello A; Bokvist K; Braun M; Eliasson L; Holmes W E; Köhler M; Rorsman P; Thévenod F
The stimulatory action of tolbutamide on Ca2+-dependent exocytosis in pancreatic beta cells is mediated by a 65-kDa mdr-like P-glycoprotein.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(10):5539-44.
1999: Wang L; Bhattacharjee A; Zuo Z; Hu F; Honkanen R E; Berggren P O; Li M
A low voltage-activated Ca2+ current mediates cytokine-induced pancreatic beta-cell death.
Endocrinology 1999;140(3):1200-4.
1999: Owada S; Larsson O; Arkhammar P; Katz A I; Chibalin A V; Berggren P O; Bertorello A M
Glucose decreases Na+,K+-ATPase activity in pancreatic beta-cells. An effect mediated via Ca2+-independent phospholipase A2 and protein kinase C-dependent phosphorylation of the alpha-subunit.
The Journal of biological chemistry 1999;274(4):2000-8.
1999: Chibalin A V; Ogimoto G; Pedemonte C H; Pressley T A; Katz A I; Féraille E; Berggren P O; Bertorello A M
Dopamine-induced endocytosis of Na+,K+-ATPase is initiated by phosphorylation of Ser-18 in the rat alpha subunit and Is responsible for the decreased activity in epithelial cells.
The Journal of biological chemistry 1999;274(4):1920-7.
1998: Köhler M; Norgren S; Berggren P O; Fredholm B B; Larsson O; Rhodes C J; Herbert T P; Luthman H
Changes in cytoplasmic ATP concentration parallels changes in ATP-regulated K+-channel activity in insulin-secreting cells.
FEBS letters 1998;441(1):97-102.
1998: Efanova I B; Zaitsev S V; Zhivotovsky B; Köhler M; Efendic S; Orrenius S; Berggren P O
Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration.
The Journal of biological chemistry 1998;273(50):33501-7.
1998: Zaitsev S V; Andersson M; Efanov A M; Efanova I B; Ostenson C G; Juntti-Berggren L; Berggren P O; Mutt V; Efendic S
An endogenous peptide isolated from the gut, NK-lysin, stimulates insulin secretion without changes in cytosolic free Ca2+ concentration.
FEBS letters 1998;439(3):267-70.
1998: Efanova I B; Zaitsev S V; Efanov A M; Ostenson C; Raap A; Mest H; Berggren P; Efendi
Effects of imidazoline derivative RX871024 on insulin, glucagon, and somatostatin secretion from isolated perfused rat pancreas.
Biochemical and biophysical research communications 1998;252(1):162-5.
1998: Bränström R; Leibiger I B; Leibiger B; Corkey B E; Berggren P O; Larsson O
Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel.
The Journal of biological chemistry 1998;273(47):31395-400.
1998: Brown H; Larsson O; Bränström R; Yang S N; Leibiger B; Leibiger I; Fried G; Moede T; Deeney J T; Brown G R; Jacobsson G; Rhodes C J; Braun J E; Scheller R H; Corkey B E; Berggren P O; Meister B
Cysteine string protein (CSP) is an insulin secretory granule-associated protein regulating beta-cell exocytosis.
The EMBO journal 1998;17(17):5048-58.
1998: Källström H; Islam M S; Berggren P O; Jonsson A B
Cell signaling by the type IV pili of pathogenic Neisseria.
The Journal of biological chemistry 1998;273(34):21777-82.
1998: Leibiger B; Moede T; Schwarz T; Brown G R; Köhler M; Leibiger I B; Berggren P O
Short-term regulation of insulin gene transcription by glucose.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9307-12.
1998: Bränström R; Efendic S; Berggren P O; Larsson O
Direct inhibition of the pancreatic beta-cell ATP-regulated potassium channel by alpha-ketoisocaproate.
The Journal of biological chemistry 1998;273(23):14113-8.
1998: Leibiger I B; Leibiger B; Moede T; Berggren P O
Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways.
Molecular cell 1998;1(6):933-8.
1998: Islam M S; Leibiger I; Leibiger B; Rossi D; Sorrentino V; Ekström T J; Westerblad H; Andrade F H; Berggren P O
In situ activation of the type 2 ryanodine receptor in pancreatic beta cells requires cAMP-dependent phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6145-50.
1998: Chibalin A V; Zierath J R; Katz A I; Berggren P O; Bertorello A M
Phosphatidylinositol 3-kinase-mediated endocytosis of renal Na+, K+-ATPase alpha subunit in response to dopamine.
Molecular biology of the cell 1998;9(5):1209-20.
1998: Efanov A M; Zaitsev S V; Efanova I B; Zhu S; Ostenson C G; Berggren P O; Efendic S
Signaling and sites of interaction for RX-871024 and sulfonylurea in the stimulation of insulin release.
The American journal of physiology 1998;274(4 Pt 1):E751-7.
1998: Chibalin A V; Pedemonte C H; Katz A I; Féraille E; Berggren P O; Bertorello A M
Phosphorylation of the catalyic alpha-subunit constitutes a triggering signal for Na+,K+-ATPase endocytosis.
The Journal of biological chemistry 1998;273(15):8814-9.
1998: Zhang Q; Berggren P O; Hansson A; Tally M
Insulin-like growth factor-I-induced DNA synthesis in insulin-secreting cell line RINm5F is associated with phosphorylation of the insulin-like growth factor-I receptor and the insulin receptor substrate-2.
The Journal of endocrinology 1998;156(3):573-81.
1998: Wróblewski R; Pålsgård E; Juntti-Berggren L; Berggren P O; Roomans G M
X-ray microanalysis of in situ and isolated pancreatic islets.
Pancreas 1998;16(2):134-40.
1998: Efanova I B; Zaitsev S V; Brown G; Berggren P O; Efendic S
RX871024 induces Ca2+ mobilization from thapsigargin-sensitive stores in mouse pancreatic beta-cells.
Diabetes 1998;47(2):211-8.
1998: Zhang Q; Berggren P O; Larsson O; Hall K; Tally M
Insulin-like growth factor II inhibits glucose-induced insulin exocytosis.
Biochemical and biophysical research communications 1998;243(1):117-21.
1998: Zierath J R; Frevert E U; Ryder J W; Berggren P O; Kahn B B
Evidence against a direct effect of leptin on glucose transport in skeletal muscle and adipocytes.
Diabetes 1998;47(1):1-4.
1997: Islam M S; Berggren P O
Cyclic ADP-ribose and the pancreatic beta cell: where do we stand?
Diabetologia 1997;40(12):1480-4.
1997: Larsson O; Kindmark H; Bränström R; Berggren P O
[Mechanisms of action of peroral antidiabetics. Sulfonylurea preparations block the ATP-dependent potassium channels]
Läkartidningen 1997;94(48):4473-7.
1997: Chibalin A V; Katz A I; Berggren P O; Bertorello A M
Receptor-mediated inhibition of renal Na(+)-K(+)-ATPase is associated with endocytosis of its alpha- and beta-subunits.
The American journal of physiology 1997;273(5 Pt 1):C1458-65.
1997: Ares M P; Pörn-Ares M I; Thyberg J; Juntti-Berggren L; Berggren P O; Diczfalusy U; Kallin B; Björkhem I; Orrenius S; Nilsson J
Ca2+ channel blockers verapamil and nifedipine inhibit apoptosis induced by 25-hydroxycholesterol in human aortic smooth muscle cells.
Journal of lipid research 1997;38(10):2049-61.
1997: Zaitsev S; Efanova I; Ostenson C G; Efendic S; Berggren P O
Delayed Ca2+ response to glucose in diabetic GK rat.
Biochemical and biophysical research communications 1997;239(1):129-33.
1997: Larsson O; Barker C J; Sjöholm A; Carlqvist H; Michell R H; Bertorello A; Nilsson T; Honkanen R E; Mayr G W; Zwiller J; Berggren P O
Inhibition of phosphatases and increased Ca2+ channel activity by inositol hexakisphosphate.
Science (New York, N.Y.) 1997;278(5337):471-4.
1997: Zhang Q; Berggren P O; Tally M
Glucose increases both the plasma membrane number and phosphorylation of insulin-like growth factor II/mannose 6-phosphate receptors.
The Journal of biological chemistry 1997;272(38):23703-6.
1997: Brown G R; Köhler M; Berggren P O
Parallel changes in nuclear and cytosolic calcium in mouse pancreatic beta-cells.
The Biochemical journal 1997;325 ( Pt 3)():771-8.
1997: Ostenson C G; Zaitsev S; Berggren P O; Efendic S; Langel U; Bartfai T
Galparan: a powerful insulin-releasing chimeric peptide acting at a novel site.
Endocrinology 1997;138(8):3308-13.
1997: Bränström R; Höög A; Wahl M A; Berggren P O; Larsson O
RIN14B: a pancreatic delta-cell line that maintains functional ATP-dependent K+ channels and capability to secrete insulin under conditions where it no longer secretes somatostatin.
FEBS letters 1997;411(2-3):301-7.
1997: Bränström R; Corkey B E; Berggren P O; Larsson O
Evidence for a unique long chain acyl-CoA ester binding site on the ATP-regulated potassium channel in mouse pancreatic beta cells.
The Journal of biological chemistry 1997;272(28):17390-4.
1997: Zhang Q; Tally M; Larsson O; Kennedy R T; Huang L; Hall K; Berggren P O
Insulin-like growth factor II signaling through the insulin-like growth factor II/mannose-6-phosphate receptor promotes exocytosis in insulin-secreting cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6232-7.
1997: Efanov A M; Zaitsev S V; Berggren P O
Inositol hexakisphosphate stimulates non-Ca2+-mediated and primes Ca2+-mediated exocytosis of insulin by activation of protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4435-9.
1997: Islam M S; Kindmark H; Larsson O; Berggren P O
Thiol oxidation by 2,2'-dithiodipyridine causes a reversible increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells. Role for inositol 1,4,5-trisphosphate-sensitive Ca2+ stores.
The Biochemical journal 1997;321 ( Pt 2)():347-54.
1996: Agrup C; Berggren P O; Köhler M; Spångberg M L; Bagger-Sjöbäck D
Morphological and functional characteristics of the different cell types in the stria vascularis: a comparison between cells obtained from fresh tissue preparations and cells cultured in vitro.
Hearing research 1996;102(1-2):155-66.
1996: Zaitsev S V; Efanov A M; Efanova I B; Larsson O; Ostenson C G; Gold G; Berggren P O; Efendic S
Imidazoline compounds stimulate insulin release by inhibition of K(ATP) channels and interaction with the exocytotic machinery.
Diabetes 1996;45(11):1610-8.
1996: Webb D L; Islam M S; Efanov A M; Brown G; Köhler M; Larsson O; Berggren P O
Insulin exocytosis and glucose-mediated increase in cytoplasmic free Ca2+ concentration in the pancreatic beta-cell are independent of cyclic ADP-ribose.
The Journal of biological chemistry 1996;271(32):19074-9.
1996: Abdel-Halim S M; Guenifi A; Khan A; Larsson O; Berggren P O; Ostenson C G; Efendic S
Impaired coupling of glucose signal to the exocytotic machinery in diabetic GK rats: a defect ameliorated by cAMP.
Diabetes 1996;45(7):934-40.
1996: Deeney J T; Cunningham B A; Chheda S; Bokvist K; Juntti-Berggren L; Lam K; Korchak H M; Corkey B E; Berggren P O
Reversible Ca2+-dependent translocation of protein kinase C and glucose-induced insulin release.
The Journal of biological chemistry 1996;271(30):18154-60.
1996: Larsson O; Kindmark H; Brandstrom R; Fredholm B; Berggren P O
Oscillations in KATP channel activity promote oscillations in cytoplasmic free Ca2+ concentration in the pancreatic beta cell.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):5161-5.
1996: Larsson O; Deeney J T; Bränström R; Berggren P O; Corkey B E
Activation of the ATP-sensitive K+ channel by long chain acyl-CoA. A role in modulation of pancreatic beta-cell glucose sensitivity.
The Journal of biological chemistry 1996;271(18):10623-6.
1996: Zhou Y P; Berggren P O; Grill V
A fatty acid-induced decrease in pyruvate dehydrogenase activity is an important determinant of beta-cell dysfunction in the obese diabetic db/db mouse.
Diabetes 1996;45(5):580-6.
1996: Josefsen K; Stenvang J P; Kindmark H; Berggren P O; Horn T; Kjaer T; Buschard K
Fluorescence-activated cell sorted rat islet cells and studies of the insulin secretory process.
The Journal of endocrinology 1996;149(1):145-54.
1996: Nilsson T; Schultz V; Berggren P O; Corkey B E; Tornheim K
Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic beta-cells.
The Biochemical journal 1996;314 ( Pt 1)():91-4.
1996: Eliasson L; Renström E; Ammälä C; Berggren P O; Bertorello A M; Bokvist K; Chibalin A; Deeney J T; Flatt P R; Gäbel J; Gromada J; Larsson O; Lindström P; Rhodes C J; Rorsman P
PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells.
Science (New York, N.Y.) 1996;271(5250):813-5.
1995: Zaitsev S V; Efendic S; Arkhammar P; Bertorello A M; Berggren P O
Dissociation between changes in cytoplasmic free Ca2+ concentration and insulin secretion as evidenced from measurements in mouse single pancreatic islets.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9712-6.
1995: Cooney R V; Harwood P J; Franke A A; Narala K; Sundström A K; Berggren P O; Mordan L J
Products of gamma-tocopherol reaction with NO2 and their formation in rat insulinoma (RINm5F) cells.
Free radical biology & medicine 1995;19(3):259-69.
1995: Kindmark H; Køohler M; Larsson O; Khan A; Berggren P O
Dissociation between exocytosis and Ca(2+)-channel activity in mouse pancreatic beta-cells stimulated with calmidazolium (compound R24571).
FEBS letters 1995;369(2-3):315-20.
1995: Sjöholm A; Honkanen R E; Berggren P O
Inhibition of serine/threonine protein phosphatases by secretagogues in insulin-secreting cells.
Endocrinology 1995;136(8):3391-7.
1995: Eizirik D L; Sandler S; Welsh N; Juntti-Berggren L; Berggren P O
Interleukin-1 beta-induced stimulation of insulin release in mouse pancreatic islets is related to diacylglycerol production and protein kinase C activation.
Molecular and cellular endocrinology 1995;111(2):159-65.
1995: Barker C J; French P J; Moore A J; Nilsson T; Berggren P O; Bunce C M; Kirk C J; Michell R H
Inositol 1,2,3-trisphosphate and inositol 1,2- and/or 2,3-bisphosphate are normal constituents of mammalian cells.
The Biochemical journal 1995;306 ( Pt 2)():557-64.
1995: Islam M S; Larsson O; Nilsson T; Berggren P O
Effects of caffeine on cytoplasmic free Ca2+ concentration in pancreatic beta-cells are mediated by interaction with ATP-sensitive K+ channels and L-type voltage-gated Ca2+ channels but not the ryanodine receptor.
The Biochemical journal 1995;306 ( Pt 3)():679-86.
1995: Pålsgård E; Lindh U; Juntti-Berggren L; Berggren P O; Roomans G M
Effects of K(+)-induced depolarization and purinergic receptor activation on elemental content in insulin-producing RINm5F-cells.
Cell biology international 1995;19(1):25-34.
1994: Jacobsson G; Bean A J; Scheller R H; Juntti-Berggren L; Deeney J T; Berggren P O; Meister B
Identification of synaptic proteins and their isoform mRNAs in compartments of pancreatic endocrine cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12487-91.
1994: Kindmark H; Köhler M; Arkhammar P; Efendic S; Larsson O; Linder S; Nilsson T; Berggren P O
Oscillations in cytoplasmic free calcium concentration in human pancreatic islets from subjects with normal and impaired glucose tolerance.
Diabetologia 1994;37(11):1121-31.
1994: Kass G E; Chow S C; Gahm A; Webb D L; Berggren P O; Llopis J; Orrenius S
Two separate plasma membrane Ca2+ carriers participate in receptor-mediated Ca2+ influx in rat hepatocytes.
Biochimica et biophysica acta 1994;1223(2):226-33.
1994: Kass G E; Webb D L; Chow S C; Llopis J; Berggren P O
Receptor-mediated Mn2+ influx in rat hepatocytes: comparison of cells loaded with Fura-2 ester and cells microinjected with Fura-2 salt.
The Biochemical journal 1994;302 ( Pt 1)():5-9.
1994: Kindmark H; Köhler M; Gerwins P; Larsson O; Khan A; Wahl M A; Berggren P O
The imidazoline derivative calmidazolium inhibits voltage-gated Ca(2+)-channels and insulin release but has no effect on the phospholipase C system in insulin producing RINm5F-cells.
Bioscience reports 1994;14(3):145-58.
1994: Ammälä C; Eliasson L; Bokvist K; Berggren P O; Honkanen R E; Sjöholm A; Rorsman P
Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4343-7.
1994: Juntti-Berggren L; Civelek V N; Berggren P O; Schultz V; Corkey B E; Tornheim K
Glucose-stimulated increase in cytoplasmic pH precedes increase in free Ca2+ in pancreatic beta-cells. A possible role for pyruvate.
The Journal of biological chemistry 1994;269(20):14391-5.
1994: Haby C; Larsson O; Islam M S; Aunis D; Berggren P O; Zwiller J
Inhibition of serine/threonine protein phosphatases promotes opening of voltage-activated L-type Ca2+ channels in insulin-secreting cells.
The Biochemical journal 1994;298 ( Pt 2)():341-6.
1994: Flatt P R; Shibier O; Szecowka J; Berggren P O
New perspectives on the actions of sulphonylureas and hyperglycaemic sulphonamides on the pancreatic beta-cell.
Diabète & métabolisme 1994;20(2):157-62.
1994: Berggren P O; Larsson O
Ca2+ and pancreatic B-cell function.
Biochemical Society transactions 1994;22(1):12-8.
1994: Arkhammar P; Juntti-Berggren L; Larsson O; Welsh M; Nånberg E; Sjöholm A; Köhler M; Berggren P O
Protein kinase C modulates the insulin secretory process by maintaining a proper function of the beta-cell voltage-activated Ca2+ channels.
The Journal of biological chemistry 1994;269(4):2743-9.
1994: Barker C J; Nilsson T; Kirk C J; Michell R H; Berggren P O
Simultaneous oscillations of cytoplasmic free Ca2+ concentration and Ins(1,4,5)P3 concentration in mouse pancreatic beta-cells.
The Biochemical journal 1994;297 ( Pt 2)():265-8.
1994: Pålsgård E; Lindh U; Juntti-Berggren L; Berggren P O; Roomans G M; Grime G W
Proton-induced and electron-induced X-ray microanalysis of insulin-secreting cells.
Scanning microscopy. Supplement 1994;8():325-32; discussion 332-3.
1993: Rossi A D; Larsson O; Manzo L; Orrenius S; Vahter M; Berggren P O; Nicotera P
Modifications of Ca2+ signaling by inorganic mercury in PC12 cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(15):1507-14.
1993: Islam M S; Larsson O; Berggren P O
Cyclic ADP-ribose and pancreatic beta cells.
Science (New York, N.Y.) 1993;262(5139):1499.
1993: Sjöholm A; Honkanen R E; Berggren P O
Characterization of serine/threonine protein phosphatases in RINm5F insulinoma cells.
Bioscience reports 1993;13(6):349-58.
1993: Sjöholm A; Arkhammar P; Welsh N; Bokvist K; Rorsman P; Hallberg A; Nilsson T; Welsh M; Berggren P O
Enhanced stimulus-secretion coupling in polyamine-depleted rat insulinoma cells. An effect involving increased cytoplasmic Ca2+, inositol phosphate generation, and phorbol ester sensitivity.
The Journal of clinical investigation 1993;92(4):1910-7.
1993: Islam M S; Larsson O; Berggren P O
Cyclic ADP-ribose in beta cells.
Science (New York, N.Y.) 1993;262(5133):584-6.
1993: Islam M S; Berggren P O
Mobilization of Ca2+ by thapsigargin and 2,5-di-(t-butyl)-1,4-benzohydroquinone in permeabilized insulin-secreting RINm5F cells: evidence for separate uptake and release compartments in inositol 1,4,5-trisphosphate-sensitive Ca2+ pool.
The Biochemical journal 1993;293 ( Pt 2)():423-9.
1993: Islam M S; Berggren P O; Larsson O
Sulfhydryl oxidation induces rapid and reversible closure of the ATP-regulated K+ channel in the pancreatic beta-cell.
FEBS letters 1993;319(1-2):128-32.
1993: Ammälä C; Bokvist K; Larsson O; Berggren P O; Rorsman P
Demonstration of a novel apamin-insensitive calcium-activated K+ channel in mouse pancreatic B cells.
Pflügers Archiv : European journal of physiology 1993;422(5):443-8.
1993: Berggren P O; Arkhammar P; Islam M S; Juntti-Berggren L; Khan A; Kindmark H; Köhler M; Larsson K; Larsson O; Nilsson T
Regulation of cytoplasmic free Ca2+ in insulin-secreting cells.
Advances in experimental medicine and biology 1993;334():25-45.
1992: Prieto J; Kaaya E E; Juntti-Berggren L; Berggren P O; Sandler S; Biberfeld P; Patarroyo M
Induction of intercellular adhesion molecule-1 (CD54) on isolated mouse pancreatic beta cells by inflammatory cytokines.
Clinical immunology and immunopathology 1992;65(3):247-53.
1992: Juntti-Berggren L; Rorsman P; Siffert W; Berggren P O
Intracellular pH and the stimulus-secretion coupling in insulin-producing RINm5F cells.
The Biochemical journal 1992;287 ( Pt 1)():59-66.
1992: Khan A; Ostenson C G; Berggren P O; Efendic S
Glucocorticoid increases glucose cycling and inhibits insulin release in pancreatic islets of ob/ob mice.
The American journal of physiology 1992;263(4 Pt 1):E663-6.
1992: Lerner U H; Brunius G; Andurén I; Berggren P O; Juntti-Berggren L; Modéer T
Bradykinin induces a B2 receptor-mediated calcium signal linked to prostanoid formation in human gingival fibroblasts in vitro.
Agents and actions 1992;37(1-2):44-52.
1992: Rorsman P; Ammälä C; Berggren P O; Bokvist K; Larsson O
Cytoplasmic calcium transients due to single action potentials and voltage-clamp depolarizations in mouse pancreatic B-cells.
The EMBO journal 1992;11(8):2877-84.
1992: Kindmark H; Köhler M; Efendic S; Rorsman P; Larsson O; Berggren P O
Protein kinase C activity affects glucose-induced oscillations in cytoplasmic free Ca2+ in the pancreatic B-cell.
FEBS letters 1992;303(1):85-90.
1992: Islam M S; Rorsman P; Berggren P O
Ca(2+)-induced Ca2+ release in insulin-secreting cells.
FEBS letters 1992;296(3):287-91.
1992: Ammälä C; Berggren P O; Bokvist K; Rorsman P
Inhibition of L-type calcium channels by internal GTP [gamma S] in mouse pancreatic beta cells.
Pflügers Archiv : European journal of physiology 1992;420(1):72-7.
1992: Juntti-Berggren L; Lindh U; Berggren P O; Frankel B J
Elemental composition in the pancreatic B cell is normal in the prediabetic Chinese hamster.
Pancreas 1992;7(1):11-4.
1991: Juntti-Berggren L; Arkhammar P; Nilsson T; Rorsman P; Berggren P O
Glucose-induced increase in cytoplasmic pH in pancreatic beta-cells is mediated by Na+/H+ exchange, an effect not dependent on protein kinase C.
The Journal of biological chemistry 1991;266(35):23537-41.
1991: Kindmark H; Köhler M; Nilsson T; Arkhammar P; Wiechel K L; Rorsman P; Efendic S; Berggren P O
Measurements of cytoplasmic free Ca2+ concentration in human pancreatic islets and insulinoma cells.
FEBS letters 1991;291(2):310-4.
1991: Ammälä C; Larsson O; Berggren P O; Bokvist K; Juntti-Berggren L; Kindmark H; Rorsman P
Inositol trisphosphate-dependent periodic activation of a Ca(2+)-activated K+ conductance in glucose-stimulated pancreatic beta-cells.
Nature 1991;353(6347):849-52.
1991: Chandramouli V; Khan A; Ostenson C G; Berggren P O; Löw H; Landau B R; Efendic S E
Quantification of glucose cycling and the extent of equilibration of glucose 6-phosphate with fructose 6-phosphate in islets from ob/ob mice.
The Biochemical journal 1991;278 ( Pt 2)():353-9.
1991: Niki I; Welsh M; Berggren P O; Hubbard P; Ashcroft S J
Characterization of the solubilized glibenclamide receptor in a hamster pancreatic beta-cell line, HIT T15.
The Biochemical journal 1991;277 ( Pt 3)():619-24.
1991: Modéer T; Brunius G; Mendez C; Juntti-Berggren L; Berggren P O
Influence of phenytoin on cytoplasmic free Ca2+ level in human gingival fibroblasts.
Scandinavian journal of dental research 1991;99(4):310-5.
1991: Islam M S; Nilsson T; Rorsman P; Berggren P O
Interaction with the inositol 1,4,5-trisphosphate receptor promotes Ca2+ sequestration in permeabilised insulin-secreting cells.
FEBS letters 1991;288(1-2):27-9.
1991: Rorsman P; Ashcroft F M; Berggren P O
Regulation of glucagon release from pancreatic A-cells.
Biochemical pharmacology 1991;41(12):1783-90.
1991: Bokvist K; Ammälä C; Berggren P O; Rorsman P; Wåhlander K
Alpha 2-adrenoreceptor stimulation does not inhibit L-type calcium channels in mouse pancreatic beta-cells.
Bioscience reports 1991;11(3):147-57.
1991: Juntti-Berggren L; Lindh U; Berggren P O
Starvation is associated with changes in the elemental composition of the pancreatic beta-cell.
Bioscience reports 1991;11(2):73-84.
1991: Milin C; Radosevic-Stasic B; Kirigin M; Hinic V; Rukavina D; Berggren P O; Efendic S
Somatostatin promotes accumulation of phospholipids in regenerating liver tissue of rats.
Bioscience reports 1991;11(1):1-6.
1991: Bokvist K; Ammälä C; Ashcroft F M; Berggren P O; Larsson O; Rorsman P
Separate processes mediate nucleotide-induced inhibition and stimulation of the ATP-regulated K(+)-channels in mouse pancreatic beta-cells.
Proceedings. Biological sciences / The Royal Society 1991;243(1307):139-44.
1991: Rorsman P; Bokvist K; Ammälä C; Arkhammar P; Berggren P O; Larsson O; Wåhlander K
Activation by adrenaline of a low-conductance G protein-dependent K+ channel in mouse pancreatic B cells.
Nature 1991;349(6304):77-9.
1991: Ahrén B; Berggren P O; Rorsman P; Ostenson C G; Efendic S
Neuropeptides in the regulation of islet hormone secretion--localization, effects and mode of action.
Advances in experimental medicine and biology 1991;291():129-42.
1991: Efendic S; Kindmark H; Berggren P O
Mechanisms involved in the regulation of the insulin secretory process.
Journal of internal medicine. Supplement 1991;735():9-22.
1990: Arkhammar P; Nilsson T; Berggren P O
Glucose-stimulated efflux of indo-1 from pancreatic beta-cells is reduced by probenecid.
FEBS letters 1990;273(1-2):182-4.
1990: Nicotera P; Orrenius S; Nilsson T; Berggren P O
An inositol 1,4,5-trisphosphate-sensitive Ca2+ pool in liver nuclei.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(17):6858-62.
1990: Welsh M; Claesson-Welsh L; Hallberg A; Welsh N; Betsholtz C; Arkhammar P; Nilsson T; Heldin C H; Berggren P O
Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5807-11.
1990: Smith P A; Bokvist K; Arkhammar P; Berggren P O; Rorsman P
Delayed rectifying and calcium-activated K+ channels and their significance for action potential repolarization in mouse pancreatic beta-cells.
The Journal of general physiology 1990;95(6):1041-59.
1990: Khan A; Chandramouli V; Ostenson C G; Berggren P O; Löw H; Landau B R; Efendic S
Glucose cycling is markedly enhanced in pancreatic islets of obese hyperglycemic mice.
Endocrinology 1990;126(5):2413-6.
1990: Juntti-Berggren L; Lindh U; Berggren P O; Berglund O; Frankel B J
Diabetes is not associated with a change in the elemental composition of the pancreatic B cell in diabetic C57BL KsJ-db/db mice.
Bioscience reports 1990;10(2):217-23.
1990: Rorsman P; Berggren P O; Smith P A
Glucose in glucagon release.
Nature 1990;344(6268):716.
1990: Betsholtz C; Baumann A; Kenna S; Ashcroft F M; Ashcroft S J; Berggren P O; Grupe A; Pongs O; Rorsman P; Sandblom J
Expression of voltage-gated K+ channels in insulin-producing cells. Analysis by polymerase chain reaction.
FEBS letters 1990;263(1):121-6.
1990: Berggren P O; Rorsman P; Arkhammar P; Nilsson T
Mechanisms of action of entero-insular hormones and neural input on the insulin secretory process.
Biochemical Society transactions 1990;18(1):119-22.
1990: Arkhammar P; Hallberg A; Kindmark H; Nilsson T; Rorsman P; Berggren P O
Extracellular ATP increases cytoplasmic free Ca2+ concentration in clonal insulin-producing RINm5F cells. A mechanism involving direct interaction with both release and refilling of the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool.
The Biochemical journal 1990;265(1):203-11.
1989: Arkhammar P; Nilsson T; Welsh M; Welsh N; Berggren P O
Effects of protein kinase C activation on the regulation of the stimulus-secretion coupling in pancreatic beta-cells.
The Biochemical journal 1989;264(1):207-15.
1989: Berggren P O; Arkhammar P; Nilsson T
Activation of protein kinase C assists insulin producing cells in recovery from raised cytoplasmic Ca2+ by stimulating Ca2+ efflux.
Biochemical and biophysical research communications 1989;165(1):416-21.
1989: Welsh N; Nilsson T; Hallberg A; Arkhammar P; Berggren P O; Sandler S
Human interleukin 1 beta stimulates islet insulin release by a mechanism not dependent on changes in phospholipase C and protein kinase C activities or Ca2+ handling.
Acta endocrinologica 1989;121(5):698-704.
1989: Rorsman P; Berggren P O; Bokvist K; Ericson H; Möhler H; Ostenson C G; Smith P A
Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels.
Nature 1989;341(6239):233-6.
1989: Sagulin G B; Müller R M; Westlind-Danielsson A; Nilsson T; Berggren P O; Roomans G M
Mechanism of action of calcitonin on secretion in rat submandibular gland.
Acta physiologica Scandinavica 1989;136(3):435-42.
1989: Rorsman P; Arkhammar P; Bokvist K; Hellerström C; Nilsson T; Welsh M; Welsh N; Berggren P O
Failure of glucose to elicit a normal secretory response in fetal pancreatic beta cells results from glucose insensitivity of the ATP-regulated K+ channels.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4505-9.
1989: Berggren P O; Hallberg A; Welsh N; Arkahammar P; Nilsson T; Welsh M
Transfection of insulin-producing cells with a transforming c-Ha-ras oncogene stimulates phospholipase C activity.
The Biochemical journal 1989;259(3):701-7.
1989: Boynton A L; Cooney R V; Hill T D; Nilsson T; Arkhammar P; Berggren P O
Extracellular ATP mobilizes intracellular Ca2+ in T51B rat liver epithelial cells: a study involving single cell measurements.
Experimental cell research 1989;181(1):245-55.
1989: Flatt P R; Juntti-Berggren L; Berggren P O; Gould B J; Swanston-Flatt S K
Failure of glucose tolerance factor-containing Brewer's yeast to ameliorate spontaneous diabetes in C57BL/KsJ DB/DB mice.
Diabetes research (Edinburgh, Scotland) 1989;10(3):147-51.
1989: Flatt P R; Juntti-Berggren L; Berggren P O; Gould B J; Swanston-Flatt S K
Effects of dietary inorganic trivalent chromium (Cr3+) on the development of glucose homeostasis in rats.
Diabète & métabolisme 1989;15(2):93-7.
1989: Ahrén B; Berggren P O; Bokvist K; Rorsman P
Does galanin inhibit insulin secretion by opening of the ATP-regulated K+ channel in the beta-cell?
Peptides 1989;10(2):453-7.
1989: Arkhammar P; Nilsson T; Berggren P O
Glucose-stimulated efflux of fura-2 in pancreatic beta-cells is prevented by probenecid.
Biochemical and biophysical research communications 1989;159(1):223-8.
1989: Arkhammar P; Nilsson T; Berggren P O
Glucose-induced changes in cytoplasmic free Ca2+ concentration and the significance for the regulation of insulin release. Measurements with fura-2 in suspensions and single aggregates of mouse pancreatic beta-cells.
Cell calcium 1989;10(1):17-27.
1989: Nilsson T; Arkhammar P; Rorsman P; Berggren P O
Suppression of insulin release by galanin and somatostatin is mediated by a G-protein. An effect involving repolarization and reduction in cytoplasmic free Ca2+ concentration.
The Journal of biological chemistry 1989;264(2):973-80.
1988: Ashcroft F M; Ashcroft S J; Berggren P O; Betzholz C; Rorsman P; Trube G; Welsh M
Expression of K channels in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting beta-cell line, HIT T15.
FEBS letters 1988;239(2):185-9.
1988: Flatt P R; Abrahamsson H; Arkhammar P; Berggren P O; Rorsman P; Swanston-Flatt S K
Measurements of membrane potential, transmembrane 45Ca fluxes, cytoplasmic free Ca2+ concentration and insulin release by transplantable rat insulinoma cells maintained in tissue culture.
British journal of cancer 1988;58(1):22-9.
1988: Nilsson T; Arkhammar P; Berggren P O
Dual effect of glucose on cytoplasmic free Ca2+ concentration and insulin release reflects the beta-cell being deprived of fuel.
Biochemical and biophysical research communications 1988;153(3):984-91.
1988: Karlsson J; Cummins P; Smith H J; Berggren P O; Saartok T
Effects of chronic sympathectomy on muscle fibre composition ISO-myosin patterns, protein synthesis and calcium content in canine gracilis muscle.
Clinical physiology (Oxford, England) 1988;8(2):181-91.
1988: Ahrén B; Rorsman P; Berggren P O
Galanin and the endocrine pancreas.
FEBS letters 1988;229(2):233-7.
1988: Nilsson T; Zwiller J; Boynton A L; Berggren P O
Heparin inhibits IP3-induced Ca2+ release in permeabilized pancreatic beta-cells.
FEBS letters 1988;229(1):211-4.
1988: Nilsson T; Arkhammar P; Rorsman P; Berggren P O
Inhibition of glucose-stimulated insulin release by alpha 2-adrenoceptor activation is parallelled by both a repolarization and a reduction in cytoplasmic free Ca2+ concentration.
The Journal of biological chemistry 1988;263(4):1855-60.
1988: Welsh M; Welsh N; Nilsson T; Arkhammar P; Pepinsky R B; Steiner D F; Berggren P O
Stimulation of pancreatic islet beta-cell replication by oncogenes.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(1):116-20.
1987: Naeser P; Brolin S E; Berggren P O
The sorbitol shunt in the retina and the optic nerve of mice with inherited and STZ-induced diabetes.
Acta ophthalmologica 1987;65(6):693-8.
1987: Nilsson T; Arkhammar P; Hallberg A; Hellman B; Berggren P O
Characterization of the inositol 1,4,5-trisphosphate-induced Ca2+ release in pancreatic beta-cells.
The Biochemical journal 1987;248(2):329-36.
1987: Hill T D; Berggren P O; Boynton A L
Heparin inhibits inositol trisphosphate-induced calcium release from permeabilized rat liver cells.
Biochemical and biophysical research communications 1987;149(3):897-901.
1987: Nilsson T; Arkhammar P; Berggren P O
Extracellular Ca2+ induces a rapid increase in cytoplasmic free Ca2+ in pancreatic beta-cells.
Biochemical and biophysical research communications 1987;149(1):152-8.
1987: Curstedt T; Jörnvall H; Robertson B; Bergman T; Berggren P
Two hydrophobic low-molecular-mass protein fractions of pulmonary surfactant. Characterization and biophysical activity.
European journal of biochemistry / FEBS 1987;168(2):255-62.
1987: Nilsson T; Berggren P O; Hellman B
Cadmium-induced insulin release does not involve changes in intracellular handling of calcium.
Biochimica et biophysica acta 1987;929(1):81-7.
1987: Hoftiezer V; Bankston P W; Berggren P O
Evidence for the presence of virus in clonal insulin-producing RINm5F cells.
Experientia 1987;43(4):420-1.
1987: Arkhammar P; Nilsson T; Rorsman P; Berggren P O
Inhibition of ATP-regulated K+ channels precedes depolarization-induced increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells.
The Journal of biological chemistry 1987;262(12):5448-54.
1987: Juntti-Berggren L; Lindh U; Berggren P O; Frankel B J
Proton microprobe analysis of 15 elements in pancreatic B cells and exocrine pancreas in diabetic Chinese hamsters.
Bioscience reports 1987;7(1):33-41.
1986: Rorsman P; Arkhammar P; Berggren P O
Voltage-activated Na+ currents and their suppression by phorbol ester in clonal insulin-producing RINm5F cells.
The American journal of physiology 1986;251(6 Pt 1):C912-9.
1986: Ahrén B; Arkhammar P; Berggren P O; Nilsson T
Galanin inhibits glucose-stimulated insulin release by a mechanism involving hyperpolarization and lowering of cytoplasmic free Ca2+ concentration.
Biochemical and biophysical research communications 1986;140(3):1059-63.
1986: Nilsson T; Rorsman F; Berggren P O; Hellman B
Accumulation of cadmium in pancreatic beta cells is similar to that of calcium in being stimulated by both glucose and high potassium.
Biochimica et biophysica acta 1986;888(3):270-7.
1986: Berggren P O; Sohtell M
Microelectrode studies of D-glucose- and K+-induced changes in membrane potential of electrofused insulin-producing cells.
FEBS letters 1986;202(2):367-72.
1986: Arkhammar P; Nilsson T; Berggren P O
Stimulation of insulin release by the phorbol ester 12-O-tetradecanoylphorbol 13-acetate in the clonal cell line RINm5F despite a lowering of the free cytoplasmic Ca2+ concentration.
Biochimica et biophysica acta 1986;887(2):236-41.
1986: Arkhammar P; Berggren P O; Rorsman P
Direct evidence for opposite effects of D-glucose and D-glyceraldehyde on cytoplasmic pH of mouse pancreatic beta-cells.
Bioscience reports 1986;6(4):355-61.
1985: Hoftiezer V; Berggren P O; Hellman B
Effects of zinc during culture of an insulin-producing rat cell line (RINm5F).
Cancer letters 1985;29(1):15-22.
1985: Abrahamsson H; Berggren P O; Rorsman P
Direct measurements of increased free cytoplasmic Ca2+ in mouse pancreatic beta-cells following stimulation by hypoglycemic sulfonylureas.
FEBS letters 1985;190(1):21-4.
1985: Abrahamsson H; Anderson T; Berggren P O; Pertoft H
Isolation of a purified mitochondrial fraction from viable clonal insulin-producing cells (RINm5F) by Percoll density gradient centrifugation.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1985;21(7):415-20.
1985: Hoftiezer V; Berggren P O; Hellman B
Effects of altered Ca2+ and Mg2+ concentrations on proliferation and functional differentiation of the clonal insulin-producing cells RINm5F.
Cancer letters 1985;27(1):7-14.
1985: Berggren P O; Flatt P R
Endogenous chromium in tissues and body fluids of normal and genetically diabetic (db/db) mice.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1985;17(3):164-5.
1985: Hoftiezer V; Berggren P O; Hellman B
Effects of glucose deprivation and altered Ca2+ concentrations on clonal insulin-producing cells (RINm5F).
Biomedica biochimica acta 1985;44(1):77-84.
1985: Lindh U; Juntti-Berggren L; Berggren P O; Hellman B
Proton microprobe analysis of pancreatic beta-cells.
Biomedica biochimica acta 1985;44(1):55-61.
1984: Abrahamsson H; Berggren P O; Hellman B
Mobilization of 45Ca from insulin-producing RINm5F cells attached to microcarriers.
The American journal of physiology 1984;247(6 Pt 1):E719-25.
1983: Rorsman P; Berggren P O; Gylfe E; Hellman B
Reduction of the cytosolic calcium activity in clonal insulin-releasing cells exposed to glucose.
Bioscience reports 1983;3(10):939-46.
1983: Berggren P O; Bergsten P; Gylfe E; Larsson R; Hellman B
Interactions between magnesium and calcium in beta-cell-rich pancreatic islets.
The American journal of physiology 1983;244(6):E541-7.
1982: Ostenson C G; Swenne I; Flatt P R; Berggren P O
Insulin antibody production in guinea pigs is accompanied by disturbances in pancreatic islet morphology and glucagon secretion.
Diabète & métabolisme 1982;8(3):241-7.
1982: Berggren P O; Andersson B; Hellman B
Stimulation of the insulin secretory mechanism following barium accumulation in pancreatic beta-cells.
Biochimica et biophysica acta 1982;720(3):320-8.
1982: Rorsman P; Berggren P O; Hellman B
Manganese accumulation in pancreatic beta-cells and its stimulation by glucose.
The Biochemical journal 1982;202(2):435-44.
1982: Andersson T; Berggren P O; Gylfe E; Hellman B
Amounts and distribution of intracellular magnesium and calcium in pancreatic beta-cells.
Acta physiologica Scandinavica 1982;114(2):235-41.
1982: Bergsten P; Berggren P O; Larsson R; Gylfe E
Is Mg2+ important for the secretory function of the pancreatic beta-cells?
Acta biologica et medica Germanica 1982;41(12):1225-8.
1982: Stegmayr B; Berggren P O; Ronquist G; Hellman B
Calcium, magnesium, and zinc contents in organelles of prostatic origin in human seminal plasma.
Scandinavian journal of urology and nephrology 1982;16(3):199-203.
1981: Andersson T; Berggren P O; Gylfe E
Effects of glucose on the calcium content of intact beta-cells and cellular organelles.
Upsala journal of medical sciences 1981;86(2):165-70.
1981: Berggren P O
Characteristics of Ba2+-stimulated insulin release with special reference to pancreatic beta-cells sensitized by cyclic AMP.
Acta biologica et medica Germanica 1981;40(1):15-7.
1980: Hellman B; Andersson T; Berggren P O; Rorsman P
Calcium and pancreatic beta-cell function. XI. Modification of 45Ca fluxes by Na+ removal.
Biochemical medicine 1980;24(2):143-52.
1980: Flatt P R; Berggren P O; Gylfe E; Hellman B
Calcium and pancreatic beta-cell function. IX. Demonstration of lanthanide-induced inhibition of insulin secretion independent of modifications in transmembrane Ca2+ fluxes.
Endocrinology 1980;107(4):1007-13.
1980: Andersson T; Berggren P O; Flatt P R
Subcellular distribution of zinc in islet beta-cell fractions.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1980;12(6):275-6.
1980: Hellman B; Gylfe E; Berggren P O; Andersson T; Abrahamsson H; Rorsman P; Betsholtz C
Ca2+ transport in pancreatic beta-cells during glucose stimulation of insulin secretion.
Upsala journal of medical sciences 1980;85(3):321-9.
1980: Hellman B; Abrahamsson H; Andersson T; Berggren P O; Flatt P; Gylfe E; Hahn H J
Calcium movements in relation to glucose-stimulated insulin secretion.
Hormone and metabolic research. Supplement series 1980;Suppl 10():122-30.
1979: Berggren P O; Ostenson C G; Petersson B; Hellman B
Evidence for divergent glucose effects on calcium metabolism in pancreatic beta- and alpha 2-cells.
Endocrinology 1979;105(6):1463-8.
1978: Gylfe E; Buitrago A; Berggren P O; Hammarström K; Hellman B
Glucose inhibition of 45Ca efflux from pancreatic islets.
The American journal of physiology 1978;235(2):E191-6.
1978: Berggren P O; Berglund O; Hellman B
Determination of calcium in microgram amounts of dried biological material by flameless atomic absorption spectrophotometry with special reference to the pancreatic islets.
Analytical biochemistry 1978;84(2):393-401.

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