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Keith Parker

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
18
Zhao, Liping
17
Schimmer, Bernard
10
Stallings, Nancy
10
Bakke, Marit
9
Hanley, Neil
7
Caron, Kathleen
6
Majdic, Gregor
5
Bingham, Nathan
5
Ikeda, Yayoi
5
Jeyasuria, Pancharatnam
4
Hasegawa, Tomonobu
3
Ikeda, Y
3
Ingraham, Holly
3
Capel, Blanche
3
Clark, BJ

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Publications

TOP 3
Zubair Mohamad; Oka Sanae; Parker Keith L; Morohashi Ken-Ichirou
Transgenic expression of Ad4BP/SF-1 in fetal adrenal progenitor cells leads to ectopic adrenal formation.
Kim Ki Woo; Zhao Liping; Parker Keith L
Central nervous system-specific knockout of steroidogenic factor 1.
Pelusi Carla; Ikeda Yayoi; Zubair Mohamad; Parker Keith L
Impaired follicle development and infertility in female mice lacking steroidogenic factor 1 in ovarian granulosa cells.

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All Publications

2009: Zubair Mohamad; Oka Sanae; Parker Keith L; Morohashi Ken-Ichirou
Transgenic expression of Ad4BP/SF-1 in fetal adrenal progenitor cells leads to ectopic adrenal formation.
Molecular endocrinology (Baltimore, Md.) 2009;23(10):1657-67.
2009: Kim Ki Woo; Zhao Liping; Parker Keith L
Central nervous system-specific knockout of steroidogenic factor 1.
Molecular and cellular endocrinology 2009;300(1-2):132-6.
2008: Pelusi Carla; Ikeda Yayoi; Zubair Mohamad; Parker Keith L
Impaired follicle development and infertility in female mice lacking steroidogenic factor 1 in ovarian granulosa cells.
Biology of reproduction 2008;79(6):1074-83.
2008: Maatouk Danielle M; DiNapoli Leo; Alvers Ashley; Parker Keith L; Taketo Makoto M; Capel Blanche
Stabilization of beta-catenin in XY gonads causes male-to-female sex-reversal.
Human molecular genetics 2008;17(19):2949-55.
2008: Kim Alex C; Reuter Anne L; Zubair Mohamad; Else Tobias; Serecky Kerri; Bingham Nathan C; Lavery Gareth G; Parker Keith L; Hammer Gary D
Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex.
Development (Cambridge, England) 2008;135(15):2593-602.
2008: Bingham Nathan C; Anderson Kimberly K; Reuter Anne L; Stallings Nancy R; Parker Keith L
Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome.
Endocrinology 2008;149(5):2138-48.
2008: Sasaki Goro; Ishii Tomohiro; Jeyasuria Pancharatnam; Jo Youngah; Bahat Assaf; Orly Joseph; Hasegawa Tomonobu; Parker Keith L
Complex role of the mitochondrial targeting signal in the function of steroidogenic acute regulatory protein revealed by bacterial artificial chromosome transgenesis in vivo.
Molecular endocrinology (Baltimore, Md.) 2008;22(4):951-64.
2008: Lavery Gareth G; Walker Elizabeth A; Turan Nil; Rogoff Daniela; Ryder Jeffery W; Shelton John M; Richardson James A; Falciani Francesco; White Perrin C; Stewart Paul M; Parker Keith L; McMillan Daniel R
Deletion of hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy.
The Journal of biological chemistry 2008;283(13):8453-61.
2007: Kim Yuna; Bingham Nathan; Sekido Ryohei; Parker Keith L; Lovell-Badge Robin; Capel Blanche
Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(42):16558-63.
2007: Reuter Anne L; Goji Katsumi; Bingham Nathan C; Matsuo Masafumi; Parker Keith L
A novel mutation in the accessory DNA-binding domain of human steroidogenic factor 1 causes XY gonadal dysgenesis without adrenal insufficiency.
European journal of endocrinology / European Federation of Endocrine Societies 2007;157(2):233-8.
2007: Pelusi C; Zhao L; Stallings N R; Parker K L
Combined haploinsufficiency of SF-1 and GATA4 does not reveal a genetic interaction in mouse gonadal development.
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 2007;1(3):152-60.
2006: Bingham Nathan C; Verma-Kurvari Sunita; Parada Luis F; Parker Keith L
Development of a steroidogenic factor 1/Cre transgenic mouse line.
Genesis (New York, N.Y. : 2000) 2006;44(9):419-24.
2006: Lavery Gareth G; Walker Elizabeth A; Draper Nicole; Jeyasuria Pancharatnam; Marcos Josep; Shackleton Cedric H L; Parker Keith L; White Perrin C; Stewart Paul M
Hexose-6-phosphate dehydrogenase knock-out mice lack 11 beta-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation.
The Journal of biological chemistry 2006;281(10):6546-51.
2005: Nef Serge; Schaad Olivier; Stallings Nancy R; Cederroth Christopher R; Pitetti Jean-Luc; Schaer Guillaume; Malki Safia; Dubois-Dauphin Michel; Boizet-Bonhoure Brigitte; Descombes Patrick; Parker Keith L; Vassalli Jean-Dominique
Gene expression during sex determination reveals a robust female genetic program at the onset of ovarian development.
Developmental biology 2005;287(2):361-77.
2005: Segal Jeremy P; Stallings Nancy R; Lee Charlotte E; Zhao Liping; Socci Nicholas; Viale Agnes; Harris Thomas M; Soares Marcelo B; Childs Geoffrey; Elmquist Joel K; Parker Keith L; Friedman Jeffrey M
Use of laser-capture microdissection for the identification of marker genes for the ventromedial hypothalamic nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(16):4181-8.
2005: Hammer Gary D; Parker Keith L; Schimmer Bernard P
Minireview: transcriptional regulation of adrenocortical development.
Endocrinology 2005;146(3):1018-24.
2005: Wilson Megan J; Jeyasuria Pancharatnam; Parker Keith L; Koopman Peter
The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development.
The Journal of biological chemistry 2005;280(7):5917-23.
2004: Parker Keith L
Tissue-specific knockouts of steroidogenic factor 1.
Endocrine research 2004;30(4):855.
2004: Davis Aline M; Seney Marianne L; Stallings Nancy R; Zhao Liping; Parker Keith L; Tobet Stuart A
Loss of steroidogenic factor 1 alters cellular topography in the mouse ventromedial nucleus of the hypothalamus.
Journal of neurobiology 2004;60(4):424-36.
2004: Cui Shiying; Ross Andrea; Stallings Nancy; Parker Keith L; Capel Blanche; Quaggin Susan E
Disrupted gonadogenesis and male-to-female sex reversal in Pod1 knockout mice.
Development (Cambridge, England) 2004;131(16):4095-105.
2004: Jeyasuria Pancharatnam; Ikeda Yayoi; Jamin Soazik P; Zhao Liping; De Rooij Dirk G; Themmen Axel P N; Behringer Richard R; Parker Keith L
Cell-specific knockout of steroidogenic factor 1 reveals its essential roles in gonadal function.
Molecular endocrinology (Baltimore, Md.) 2004;18(7):1610-9.
2004: Correa Rafaela V; Domenice Sorahia; Bingham Nathan C; Billerbeck Ana Elisa C; Rainey William E; Parker Keith L; Mendonca Berenice B
A microdeletion in the ligand binding domain of human steroidogenic factor 1 causes XY sex reversal without adrenal insufficiency.
The Journal of clinical endocrinology and metabolism 2004;89(4):1767-72.
2004: Zhao Liping; Bakke Marit; Hanley Neil A; Majdic Gregor; Stallings Nancy R; Jeyasuria Pancharatnam; Parker Keith L
Tissue-specific knockouts of steroidogenic factor 1.
Molecular and cellular endocrinology 2004;215(1-2):89-94.
2002: Stallings Nancy R; Hanley Neil A; Majdic Gregor; Zhao Liping; Bakke Marit; Parker Keith L
Development of a transgenic green fluorescent protein lineage marker for steroidogenic factor 1.
Endocrine research 2002;28(4):497-504.
2002: Stallings Nancy R; Hanley Neil A; Majdic Gregor; Zhao Liping; Bakke Marit; Parker Keith L
Development of a transgenic green fluorescent protein lineage marker for steroidogenic factor 1.
Molecular endocrinology (Baltimore, Md.) 2002;16(10):2360-70.
2002: Ishii Tomohiro; Hasegawa Tomonobu; Pai Chin-I; Yvgi-Ohana Natalie; Timberg Rina; Zhao Liping; Majdic Gregor; Chung Bon-chu; Orly Joseph; Parker Keith L
The roles of circulating high-density lipoproteins and trophic hormones in the phenotype of knockout mice lacking the steroidogenic acute regulatory protein.
Molecular endocrinology (Baltimore, Md.) 2002;16(10):2297-309.
2002: Majdic Gregor; Young Morag; Gomez-Sanchez Elise; Anderson Paul; Szczepaniak Lidia S; Dobbins Robert L; McGarry J Denis; Parker Keith L
Knockout mice lacking steroidogenic factor 1 are a novel genetic model of hypothalamic obesity.
Endocrinology 2002;143(2):607-14.
2002: Parker Keith L; Schimmer Bernard P
Genes essential for early events in gonadal development.
Annals of medicine 2002;34(3):171-8.
2002: Parker Keith L; Rice Douglas A; Lala Deepak S; Ikeda Yayoi; Luo Xunrong; Wong Margaret; Bakke Marit; Zhao Liping; Frigeri Claudia; Hanley Neil A; Stallings Nancy; Schimmer Bernard P
Steroidogenic factor 1: an essential mediator of endocrine development.
Recent progress in hormone research 2002;57():19-36.
2001: Zhao L; Bakke M; Parker K L
Pituitary-specific knockout of steroidogenic factor 1.
Molecular and cellular endocrinology 2001;185(1-2):27-32.
2001: Parker K L; Schimmer B P
Genetics of the development and function of the adrenal cortex.
Reviews in endocrine & metabolic disorders 2001;2(3):245-52.
2001: Bakke M; Zhao L; Parker K L
Approaches to define the role of SF-1 at different levels of the hypothalamic-pituitary-steroidogenic organ axis.
Molecular and cellular endocrinology 2001;179(1-2):33-7.
2001: Zhao L; Bakke M; Krimkevich Y; Cushman L J; Parlow A F; Camper S A; Parker K L
Hypomorphic phenotype in mice with pituitary-specific knockout of steroidogenic factor 1.
Genesis (New York, N.Y. : 2000) 2001;30(2):65-9.
2001: Bakke M; Zhao L; Hanley N A; Parker K L
SF-1: a critical mediator of steroidogenesis.
Molecular and cellular endocrinology 2001;171(1-2):5-7.
2001: Hanley N A; Rainey W E; Wilson D I; Ball S G; Parker K L
Expression profiles of SF-1, DAX1, and CYP17 in the human fetal adrenal gland: potential interactions in gene regulation.
Molecular endocrinology (Baltimore, Md.) 2001;15(1):57-68.
2001: Zhao L; Bakke M; Krimkevich Y; Cushman L J; Parlow A F; Camper S A; Parker K L
Steroidogenic factor 1 (SF1) is essential for pituitary gonadotrope function.
Development (Cambridge, England) 2001;128(2):147-54.
2001: Parker K L; Schimmer B P; Schedl A
Genes essential for early events in gonadal development.
EXS 2001;(91):11-24.
2000: Bakke M; Zhao L; Hanley N A; Parker K L
Approaches to define the role of SF-1 at different levels of the hypothalamic-pituitary-steroidogenic organ axis.
Endocrine research 2000;26(4):1067-73.
2000: Hasegawa T; Zhao L; Caron K M; Majdic G; Suzuki T; Shizawa S; Sasano H; Parker K L
Developmental roles of the steroidogenic acute regulatory protein (StAR) as revealed by StAR knockout mice.
Molecular endocrinology (Baltimore, Md.) 2000;14(9):1462-71.
2000: Hanley N A; Ikeda Y; Luo X; Parker K L
Steroidogenic factor 1 (SF-1) is essential for ovarian development and function.
Molecular and cellular endocrinology 2000;163(1-2):27-32.
1999: Hanley N A; Ball S G; Clement-Jones M; Hagan D M; Strachan T; Lindsay S; Robson S; Ostrer H; Parker K L; Wilson D I
Expression of steroidogenic factor 1 and Wilms' tumour 1 during early human gonadal development and sex determination.
Mechanisms of development 1999;87(1-2):175-80.
1999: Cao G; Zhao L; Stangl H; Hasegawa T; Richardson J A; Parker K L; Hobbs H H
Developmental and hormonal regulation of murine scavenger receptor, class B, type 1.
Molecular endocrinology (Baltimore, Md.) 1999;13(9):1460-73.
1999: Parker K L; Schimmer B P; Schedl A
Genes essential for early events in gonadal development.
Cellular and molecular life sciences : CMLS 1999;55(6-7):831-8.
1999: Luo X; Ikeda Y; Lala D; Rice D; Wong M; Parker K L
Steroidogenic factor 1 (SF-1) is essential for endocrine development and function.
The Journal of steroid biochemistry and molecular biology 1999;69(1-6):13-8.
1999: Parker K L; Schedl A; Schimmer B P
Gene interactions in gonadal development.
Annual review of physiology 1999;61():417-33.
1998: Parker K L; Schimmer B P
Ahch and the feminine mystique.
Nature genetics 1998;20(4):318-9.
1998: Parker K L
The roles of steroidogenic factor 1 in endocrine development and function.
Molecular and cellular endocrinology 1998;145(1-2):15-20.
1998: Caron K M; Soo S C; Parker K L
Targeted disruption of StAR provides novel insights into congenital adrenal hyperplasia.
Endocrine research 1998;24(3-4):827-34.
1998: Parker K L
The roles of steroidogenic factor 1 in endocrine development and function.
Molecular and cellular endocrinology 1998;140(1-2):59-63.
1997: Cao G; Garcia C K; Wyne K L; Schultz R A; Parker K L; Hobbs H H
Structure and localization of the human gene encoding SR-BI/CLA-1. Evidence for transcriptional control by steroidogenic factor 1.
The Journal of biological chemistry 1997;272(52):33068-76.
1997: Caron K M; Soo S C; Wetsel W C; Stocco D M; Clark B J; Parker K L
Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11540-5.
1997: Parker K L; Schimmer B P
Steroidogenic factor 1: a key determinant of endocrine development and function.
Endocrine reviews 1997;18(3):361-77.
1997: Lala D S; Syka P M; Lazarchik S B; Mangelsdorf D J; Parker K L; Heyman R A
Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):4895-900.
1997: Caron K M; Ikeda Y; Soo S C; Stocco D M; Parker K L; Clark B J
Characterization of the promoter region of the mouse gene encoding the steroidogenic acute regulatory protein.
Molecular endocrinology (Baltimore, Md.) 1997;11(2):138-47.
1997: Caron K M; Clark B J; Ikeda Y; Parker K L
Steroidogenic factor 1 acts at all levels of the reproductive axis.
Steroids 1997;62(1):53-6.
1997: Wong M; Ikeda Y; Luo X; Caron K M; Weber T J; Swain A; Schimmer B P; Parker K L
Steroidogenic factor 1 plays multiple roles in endocrine development and function.
Recent progress in hormone research 1997;52():167-82; discussion 182-4.
1996: Ikeda Y; Swain A; Weber T J; Hentges K E; Zanaria E; Lalli E; Tamai K T; Sassone-Corsi P; Lovell-Badge R; Camerino G; Parker K L
Steroidogenic factor 1 and Dax-1 colocalize in multiple cell lineages: potential links in endocrine development.
Molecular endocrinology (Baltimore, Md.) 1996;10(10):1261-72.
1996: Wong M; Ramayya M S; Chrousos G P; Driggers P H; Parker K L
Cloning and sequence analysis of the human gene encoding steroidogenic factor 1.
Journal of molecular endocrinology 1996;17(2):139-47.
1996: Parker K L; Schimmer B P
The roles of the nuclear receptor steroidogenic factor 1 in endocrine differentiation and development.
Trends in endocrinology and metabolism: TEM 1996;7(6):203-7.
1996: Parker K L; Ikeda Y; Luo X
The roles of steroidogenic factor-1 in reproductive function.
Steroids 1996;61(4):161-5.
1995: Luo X; Ikeda Y; Parker K L
The cell-specific nuclear receptor steroidogenic factor 1 plays multiple roles in reproductive function.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1995;350(1333):279-83.
1995: Clark B J; Soo S C; Caron K M; Ikeda Y; Parker K L; Stocco D M
Hormonal and developmental regulation of the steroidogenic acute regulatory protein.
Molecular endocrinology (Baltimore, Md.) 1995;9(10):1346-55.
1995: Luo X; Ikeda Y; Schlosser D A; Parker K L
Steroidogenic factor 1 is the essential transcript of the mouse Ftz-F1 gene.
Molecular endocrinology (Baltimore, Md.) 1995;9(9):1233-9.
1995: Ikeda Y; Luo X; Abbud R; Nilson J H; Parker K L
The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus.
Molecular endocrinology (Baltimore, Md.) 1995;9(4):478-86.
1995: Luo X; Ikeda Y; Lala D S; Baity L A; Meade J C; Parker K L
A cell-specific nuclear receptor plays essential roles in adrenal and gonadal development.
Endocrine research 1995;21(1-2):517-24.
1995: Lala D S; Ikeda Y; Luo X; Baity L A; Meade J C; Parker K L
A cell-specific nuclear receptor regulates the steroid hydroxylases.
Steroids 1995;60(1):10-4.
1995: Taketo M; Parker K L; Howard T A; Tsukiyama T; Wong M; Niwa O; Morton C C; Miron P M; Seldin M F
Homologs of Drosophila Fushi-Tarazu factor 1 map to mouse chromosome 2 and human chromosome 9q33.
Genomics 1995;25(2):565-7.
1995: Parker K L; Schimmer B P
Transcriptional regulation of the genes encoding the cytochrome P-450 steroid hydroxylases.
Vitamins and hormones 1995;51():339-70.
1994: Ingraham H A; Lala D S; Ikeda Y; Luo X; Shen W H; Nachtigal M W; Abbud R; Nilson J H; Parker K L
The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis.
Genes & development 1994;8(19):2302-12.
1994: Parker K L; Schimmer B P
The role of nuclear receptors in steroid hormone production.
Seminars in cancer biology 1994;5(5):317-25.
1994: Shen W H; Moore C C; Ikeda Y; Parker K L; Ingraham H A
Nuclear receptor steroidogenic factor 1 regulates the müllerian inhibiting substance gene: a link to the sex determination cascade.
Cell 1994;77(5):651-61.
1994: Luo X; Ikeda Y; Parker K L
A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.
Cell 1994;77(4):481-90.
1994: Ikeda Y; Shen W H; Ingraham H A; Parker K L
Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases.
Molecular endocrinology (Baltimore, Md.) 1994;8(5):654-62.
1994: Clemens J W; Lala D S; Parker K L; Richards J S
Steroidogenic factor-1 binding and transcriptional activity of the cholesterol side-chain cleavage promoter in rat granulosa cells.
Endocrinology 1994;134(3):1499-508.
1993: Ikeda Y; Lala D S; Luo X; Kim E; Moisan M P; Parker K L
Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression.
Molecular endocrinology (Baltimore, Md.) 1993;7(7):852-60.
1993: Lynch J P; Lala D S; Peluso J J; Luo W; Parker K L; White B A
Steroidogenic factor 1, an orphan nuclear receptor, regulates the expression of the rat aromatase gene in gonadal tissues.
Molecular endocrinology (Baltimore, Md.) 1993;7(6):776-86.
1993: Wilson T E; Mouw A R; Weaver C A; Milbrandt J; Parker K L
The orphan nuclear receptor NGFI-B regulates expression of the gene encoding steroid 21-hydroxylase.
Molecular and cellular biology 1993;13(2):861-8.
1992: Lala D S; Rice D A; Parker K L
Steroidogenic factor I, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor I.
Molecular endocrinology (Baltimore, Md.) 1992;6(8):1249-58.
1991: Domalik L J; Chaplin D D; Kirkman M S; Wu R C; Liu W W; Howard T A; Seldin M F; Parker K L
Different isozymes of mouse 11 beta-hydroxylase produce mineralocorticoids and glucocorticoids.
Molecular endocrinology (Baltimore, Md.) 1991;5(12):1853-61.
1991: Rice D A; Mouw A R; Bogerd A M; Parker K L
A shared promoter element regulates the expression of three steroidogenic enzymes.
Molecular endocrinology (Baltimore, Md.) 1991;5(10):1552-61.
1990: Oonk R B; Parker K L; Gibson J L; Richards J S
Rat cholesterol side-chain cleavage cytochrome P-450 (P-450scc) gene. Structure and regulation by cAMP in vitro.
The Journal of biological chemistry 1990;265(36):22392-401.
1990: Rice D A; Kirkman M S; Aitken L D; Mouw A R; Schimmer B P; Parker K L
Analysis of the promoter region of the gene encoding mouse cholesterol side-chain cleavage enzyme.
The Journal of biological chemistry 1990;265(20):11713-20.
1990: Bogerd A M; Franklin A; Rice D A; Schimmer B P; Parker K L
Identification and characterization of two upstream elements that regulate adrenocortical expression of steroid 11 beta-hydroxylase.
Molecular endocrinology (Baltimore, Md.) 1990;4(6):845-50.
1990: Rice D A; Kronenberg M S; Mouw A R; Aitken L D; Franklin A; Schimmer B P; Parker K L
Multiple regulatory elements determine adrenocortical expression of steroid 21-hydroxylase.
The Journal of biological chemistry 1990;265(14):8052-8.
1989: Rice D A; Aitken L D; Vandenbark G R; Mouw A R; Franklin A; Schimmer B P; Parker K L
A cAMP-responsive element regulates expression of the mouse steroid 11 beta-hydroxylase gene.
The Journal of biological chemistry 1989;264(24):14011-5.
1989: Mouw A R; Rice D A; Meade J C; Chua S C; White P C; Schimmer B P; Parker K L
Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11 beta-hydroxylase.
The Journal of biological chemistry 1989;264(2):1305-9.

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