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William Parker

Research Profile

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TOP 3
Tao Tang; Amy Xie; Jui-Chih Chang; R Duane Davis; William Parker; Shu S Lin
Aspiration of gastric fluid in pulmonary allografts: effect of pH.
Kuei-Ying Su; Anitra D Thomas; R Duane Davis; W Michael Foster; Jui-Chih Chang; Mary Lou Everett; Zoie E Holzknecht; Monica Kraft; Sean M Lee; Jason H Leung; William Parker; Shu S Lin
Chronic aspiration shifts the immune response from adaptive immunity to innate immunity in a murine model of asthma.
William Parker; Sarah E Perkins; Matthew Harker; Michael P Muehlenbein
A prescription for clinical immunology: the pills are available and ready for testing. A review.

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All Publications

2013: Tao Tang; Amy Xie; Jui-Chih Chang; R Duane Davis; William Parker; Shu S Lin
Aspiration of gastric fluid in pulmonary allografts: effect of pH.
The Journal of surgical research 2013;181(1):e31-8.
2012: Kuei-Ying Su; Anitra D Thomas; R Duane Davis; W Michael Foster; Jui-Chih Chang; Mary Lou Everett; Zoie E Holzknecht; Monica Kraft; Sean M Lee; Jason H Leung; William Parker; Shu S Lin
Chronic aspiration shifts the immune response from adaptive immunity to innate immunity in a murine model of asthma.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2012;61(8):863-73.
2012: William Parker; Sarah E Perkins; Matthew Harker; Michael P Muehlenbein
A prescription for clinical immunology: the pills are available and ready for testing. A review.
Current medical research and opinion 2012;28(7):1193-202.
2012: Ashley M Trama; Sarah E Perkins; Kuei-Ying Su; Anitra D Thomas; Emily E Foltz; Zoie E Holzknecht; Sean M Lee; Shu S Lin; William Parker
Lymphocyte phenotypes in wild-caught rats suggest potential mechanisms underlying increased immune sensitivity in post-industrial environments.
Cellular & molecular immunology 2012;9(2):163-74.
2012: Staci D Bilbo; John P Jones; William Parker
Is autism a member of a family of diseases resulting from genetic/cultural mismatches? Implications for treatment and prevention.
Autism research and treatment 2012;2012():910946.
2011: Staci D Bilbo; Sarah E Perkins; Gregory A Wray; William Parker
Reconstitution of the human biome as the most reasonable solution for epidemics of allergic and autoimmune diseases.
Medical hypotheses 2011;77(4):494-504.
2011: Errol L Bush; Andrew S Barbas; Zoie E Holzknecht; Guerard W Byrne; Christopher G McGregor; William Parker; R Duane Davis; Shu S Lin
Coagulopathy in α-galactosyl transferase knockout pulmonary xenotransplants.
Xenotransplantation 2011;18(1):6-13.
2010: Anitra D Thomas; William Parker
Cultivation of epithelial-associated microbiota by the immune system.
Future microbiology 2010;5(10):1483-92.
2010: Sean M Lee; Aaron Wyse; Aaron Lesher; Mary Lou Everett; Linda Lou; Zoie E Holzknecht; John F Whitesides; Patricia A Spears; Dawn E Bowles; Shu S Lin; Susan L Tonkonogy; Paul E Orndorff; R Randal Bollinger; William Parker
Adaptation in a mouse colony monoassociated with Escherichia coli K-12 for more than 1,000 days.
Applied and environmental microbiology 2010;76(14):4655-63.
2010: Anitra D Thomas; Kuei-Ying Su; Jui-Chih Chang; Jason H Leung; Sean M Lee; Zoie E Holzknecht; Mary Lou Everett; William Parker; R Duane Davis; Shu S Lin
Gastroesophageal reflux-associated aspiration alters the immune response in asthma.
Surgical endoscopy 2010;24(5):1066-74.
2009: Andrew S Barbas; Aaron Lesher; Anitra D Thomas; Aaron Wyse; Aditya P Devalapalli; Yu-Huei Lee; Hung-Enn Tan; Paul E Orndorff; R Randal Bollinger; William Parker
Altering and assessing persistence of genetically modified E. coli MG1655 in the large bowel.
Experimental biology and medicine (Maywood, N.J.) 2009;234(10):1174-85.
2008: Tacy E Downing; Thomas A Sporn; R Randal Bollinger; R Duane Davis; William Parker; Shu S Lin
Pulmonary histopathology in an experimental model of chronic aspiration is independent of acidity.
Experimental biology and medicine (Maywood, N.J.) 2008;233(10):1202-12.
2008: Andrew S Barbas; T E Downing; Keki R Balsara; H E Tan; G J Rubinstein; Zoie E Holzknecht; Bradley H Collins; William Parker; R Duane Davis; Shu S Lin
Chronic aspiration shifts the immune response from Th1 to Th2 in a murine model of asthma.
European journal of clinical investigation 2008;38(8):596-602.
2008: B Li; Matthew G Hartwig; James Z Appel; Errol L Bush; Keki R Balsara; Zoie E Holzknecht; Bradley H Collins; David N Howell; William Parker; Shu S Lin; R Duane Davis
Chronic aspiration of gastric fluid induces the development of obliterative bronchiolitis in rat lung transplants.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(8):1614-21.
2007: R Randal Bollinger; Andrew S Barbas; Errol L Bush; Shu S Lin; William Parker
Biofilms in the large bowel suggest an apparent function of the human vermiform appendix.
Journal of theoretical biology 2007;249(4):826-31.
2007: R Randal Bollinger; Andrew S Barbas; Errol L Bush; Shu S Lin; William Parker
Biofilms in the normal human large bowel: fact rather than fiction.
Gut 2007;56(10):1481-2.
2007: James Z Appel; Sean M Lee; Matthew G Hartwig; Bin Li; Chong-Chao Hsieh; Edward Cantu; Yonghan Yoon; Shu S Lin; William Parker; R Duane Davis
Characterization of the innate immune response to chronic aspiration in a novel rodent model.
Respiratory research 2007;8():87.
2007: Edward Cantu; Keki R Balsara; B Li; C Lau; S Gibson; A Wyse; Kamran Baig; Jeffrey G Gaca; Gonzalo V Gonzalez-Stawinski; Timothy C Nichols; William Parker; R Duane Davis
Prolonged function of macrophage, von Willebrand factor-deficient porcine pulmonary xenografts.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(1):66-75.
2006: A P Devalapalli; Aaron Lesher; K Shieh; J S Solow; M L Everett; A S Edala; P Whitt; R R Long; N Newton; William Parker
Increased levels of IgE and autoreactive, polyreactive IgG in wild rodents: implications for the hygiene hypothesis.
Scandinavian journal of immunology 2006;64(2):125-36.
2006: Aaron Lesher; Bin Li; Parker Whitt; Nolan Newton; Aditya P Devalapalli; Karl Shieh; Jonathan S Solow; William Parker
Increased IL-4 production and attenuated proliferative and pro-inflammatory responses of splenocytes from wild-caught rats (Rattus norvegicus).
Immunology and cell biology 2006;84(4):374-82.
2006: Jeffrey G Gaca; James Z Appel; Jeffrey G Lukes; Gonzalo V Gonzalez-Stawinski; Aaron Lesher; Daniel Palestrant; John S Logan; Stephanie D Love; Zoie E Holzknecht; Jeffrey L Platt; William Parker; R Duane Davis
Effect of an anti-C5a monoclonal antibody indicates a prominent role for anaphylatoxin in pulmonary xenograft dysfunction.
Transplantation 2006;81(12):1686-94.
2006: Edward Cantu; Jeffrey G Gaca; Daniel Palestrant; Kamran Baig; Daniel J Lukes; Sarah E Gibson; Gonzalo V Gonzalez-Stawinski; Michael Olausson; William Parker; R Duane Davis
Depletion of pulmonary intravascular macrophages prevents hyperacute pulmonary xenograft dysfunction.
Transplantation 2006;81(8):1157-64.
2006: R Randal Bollinger; Mary Lou Everett; Shaina D Wahl; Yu-Huei Lee; Paul E Orndorff; William Parker
Secretory IgA and mucin-mediated biofilm formation by environmental strains of Escherichia coli: role of type 1 pili.
Molecular immunology 2006;43(4):378-87.
2006: Matthew G Hartwig; James Z Appel; Bin Li; Chong-Chao Hsieh; Yong Han Yoon; Shu S Lin; William Irish; William Parker; R Duane Davis
Chronic aspiration of gastric fluid accelerates pulmonary allograft dysfunction in a rat model of lung transplantation.
The Journal of thoracic and cardiovascular surgery 2006;131(1):209-17.
2005: Daniel J Lukes; Edward Cantu; Jeffrey G Gaca; Eva C Hallberg; Alex Karlsson-Parra; William Parker; Michael Olausson; R Duane Davis
Oral feeding with pig peripheral lymphocytes decreases the xenogeneic delayed type hypersensitivity reaction in galactosyltransferase knockout mice.
Transplantation proceedings 2005;37(8):3327-31.
2005: William Parker; Aaron Lesher
In pursuit of xenoreactive antibodies: where has it gotten us?
Immunology and cell biology 2005;83(4):413-7.
2005: Paul Yu; William Parker; Jayakar Nayak; Jeffrey L Platt
Sensitization with xenogeneic tissues alters the heavy chain repertoire of human anti-Galalpha1-3Gal antibodies.
Transplantation 2005;80(1):102-9.
2005: Jeffrey H Lawson; Kellie A Lynn; Reed M Vanmatre; Taymon Domzalski; Keith F Klemp; Thomas L Ortel; Laura E Niklason; William Parker
Antihuman factor V antibodies after use of relatively pure bovine thrombin.
The Annals of thoracic surgery 2005;79(3):1037-8.
2004: Paul E Orndorff; Aditya Devapali; Sarah Palestrant; Aaron Wyse; Mary Lou Everett; R Randal Bollinger; William Parker
Immunoglobulin-mediated agglutination of and biofilm formation by Escherichia coli K-12 require the type 1 pilus fiber.
Infection and immunity 2004;72(4):1929-38.
2004: Daniel Palestrant; Zoie E Holzknecht; Bradley H Collins; William Parker; Sara E Miller; R Randal Bollinger
Microbial biofilms in the gut: visualization by electron microscopy and by acridine orange staining.
Ultrastructural pathology 2004;28(1):23-7.
2004: Edward Cantu; William Parker; Jeffrey L Platt; R Duane Davis
Pulmonary xenotransplantation: rapidly progressing into the unknown.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4 Suppl 6():25-35.
2003: William Parker
Polyreactive antibodies and their association with xenotransplantation.
Xenotransplantation 2003;10(6):542-4.
2003: Jonathan G Schoenecker; Rachel K Johnson; Ryan C Fields; Aaron Lesher; Taymon Domzalski; Kamran Baig; Jeffrey H Lawson; William Parker
Relative purity of thrombin-based hemostatic agents used in surgery.
Journal of the American College of Surgeons 2003;197(4):580-90.
2003: Christine L Lau; Edward Cantu; Gonzalo V Gonzalez-Stawinski; Zoie E Holzknecht; Timothy C Nichols; Katherine E Posther; Cory A Rayborn; Jeffrey L Platt; William Parker; R Duane Davis
The role of antibodies and von Willebrand factor in discordant pulmonary xenotransplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(9):1065-75.
2003: R Randal Bollinger; Mary Lou Everett; Daniel Palestrant; Stephanie D Love; Shu S Lin; William Parker
Human secretory immunoglobulin A may contribute to biofilm formation in the gut.
Immunology 2003;109(4):580-7.
2003: Jeffrey G Gaca; Daniel Palestrant; Daniel J Lukes; Michael Olausson; William Parker; R Duane Davis
Prevention of acute lung injury in swine: depletion of pulmonary intravascular macrophages using liposomal clodronate.
The Journal of surgical research 2003;112(1):19-25.
2003: Mary Lou Everett; Bradley H Collins; William Parker
Kupffer cells: another player in liver tolerance induction.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2003;9(5):498-9.
2003: Mary Lou Everett; Shu S Lin; Stewart S Worrell; Jeffrey L Platt; William Parker
The footprint of antibody bound to pig cells: evidence of complex surface topology.
Biochemical and biophysical research communications 2003;301(3):751-7.
2002: Jeffrey G Gaca; Aaron Lesher; Olcay Aksoy; Zaverio M Ruggeri; William Parker; R Duane Davis
The role of the porcine von Willebrand factor: baboon platelet interactions in pulmonary xenotransplantation.
Transplantation 2002;74(11):1596-603.
2002: Jeffrey G Gaca; Aaron Lesher; Olcay Aksoy; Gonzalo V Gonzalez-Stawinski; Jeffrey L Platt; Jeffrey H Lawson; William Parker; R Duane Davis
Disseminated intravascular coagulation in association with pig-to-primate pulmonary xenotransplantation.
Transplantation 2002;73(11):1717-23.
2002: Gonzalo V Gonzalez-Stawinski; Casey W Daggett; Christine L Lau; Sujatha Karoor; Stephanie D Love; John S Logan; Jeffrey G Gaca; William Parker; R Duane Davis
Non-anti-Gal alpha1-3Gal antibody mechanisms are sufficient to cause hyperacute lung dysfunction in pulmonary xenotransplantation.
Journal of the American College of Surgeons 2002;194(6):765-73.
2002: Winston Lee; Jeffrey G Gaca; Lindsay A Edwards; Steven J Braedehoeft; William Parker; R Duane Davis
Binding of polyreactive antibodies to self versus foreign antigens.
Immunobiology 2002;205(1):95-107.
2001: Jonathan G Schoenecker; R K Johnson; Aaron Lesher; J D Day; Stephanie D Love; Maureane R Hoffman; Thomas L Ortel; William Parker; Jeffrey H Lawson
Exposure of mice to topical bovine thrombin induces systemic autoimmunity.
The American journal of pathology 2001;159(5):1957-69.
2001: Jeffrey G Gaca; Winston Lee; Olcay Aksoy; S J Braedehoeft; Gonzalo V Gonzalez-Stawinski; William Parker; R Duane Davis
Evidence for polyreactive xenoreactive antibodies in the repertoire of human anti-swine antibodies: the 'next' humoral barrier to xenotransplantation?
Transplant immunology 2001;9(1):19-27.
2001: Stephanie D Love; Winston Lee; Y C Nakamura; Jeffrey L Platt; R Randal Bollinger; William Parker
Unexpected anti-alpha GalNAc antibodies in alpha-galactosyl transferase-deficient mice: complex relationship between genotype and the natural antibody repertoire.
Immunobiology 2001;203(4):650-8.
2001: William Parker; Karyn B Stitzenberg; Paul Yu; V S Pratt; Y C Nakamura; L S Farel; C M Ward; Shu S Lin; Mary Lou Everett; Jeffrey L Platt
Biophysical characteristics of anti-Gal(alpha)1-3Gal IgM binding to cell surfaces: implications for xenotransplantation.
Transplantation 2001;71(3):440-6.
2001: Gonzalo V Gonzalez-Stawinski; Paul Yu; Stephanie D Love; William Parker; R Duane Davis
Hapten-induced primary and memory humoral responses are inhibited by the infusion of anti-CD20 monoclonal antibody (IDEC-C2B8, Rituximab).
Clinical immunology (Orlando, Fla.) 2001;98(2):175-9.
2001: William Parker; Shu S Lin; Jeffrey L Platt
Antigen expression in xenotransplantation: how low must it go?
Transplantation 2001;71(2):313-9.
2000: Shu S Lin; M J Hanaway; Gonzalo V Gonzalez-Stawinski; Christine L Lau; William Parker; R Duane Davis; Guerard W Byrne; Lisa E Diamond; John S Logan; Jeffrey L Platt
The role of anti-Galalpha1-3Gal antibodies in acute vascular rejection and accommodation of xenografts.
Transplantation 2000;70(12):1667-74.
2000: Stephanie D Love; Winston Lee; Y C Nakamura; Jeffrey L Platt; R Randal Bollinger; William Parker
Natural anti-carbohydrate IgM in mice: dependence on age and strain.
Journal of immunological methods 2000;246(1-2):61-8.
2000: Jonathan G Schoenecker; R K Hauck; M C Mercer; William Parker; Jeffrey H Lawson
Exposure to topical bovine thrombin during surgery elicits a response against the xenogeneic carbohydrate galactose alpha1-3galactose.
Journal of clinical immunology 2000;20(6):434-44.
2000: Christine L Lau; W C Daggett; MF Yeatman; PJ Chai; Shu S Lin; Andrew J Lodge; EP Chen; Lisa E Diamond; Guerard W Byrne; John S Logan; William Parker; Jeffrey L Platt; R Duane Davis
The role of antibodies in dysfunction of pig-to-baboon pulmonary transplants.
The Journal of thoracic and cardiovascular surgery 2000;120(1):29-38.
1999: William Parker; Shu S Lin; Paul Yu; A Sood; Y C Nakamura; A Song; Mary Lou Everett; Jeffrey L Platt
Naturally occurring anti-alpha-galactosyl antibodies: relationship to xenoreactive anti-alpha-galactosyl antibodies.
Glycobiology 1999;9(9):865-73.
1999: Paul Yu; William Parker; Mary Lou Everett; I J Fox; Jeffrey L Platt
Immunochemical properties of anti-Gal alpha 1-3Gal antibodies after sensitization with xenogeneic tissues.
Journal of clinical immunology 1999;19(2):116-26.
1999: Gonzalo V Gonzalez-Stawinski; William Parker; Zoie E Holzknecht; N S Huber; Jeffrey L Platt
Partial sequence of human platelet heparitinase and evidence of its ability to polymerize.
Biochimica et biophysica acta 1999;1429(2):431-8.
1998: N S Ihrcke; William Parker; K J Reissner; Jeffrey L Platt
Regulation of platelet heparanase during inflammation: role of pH and proteinases.
Journal of cellular physiology 1998;175(3):255-67.
1998: Shu S Lin; William Parker; Mary Lou Everett; Jeffrey L Platt
Differential recognition by proteins of alpha-galactosyl residues on endothelial cell surfaces.
Glycobiology 1998;8(5):433-43.
1998: MF Yeatman; Casey W Daggett; William Parker; Guerard W Byrne; John S Logan; Jeffrey L Platt; R Duane Davis
Complement-mediated pulmonary xenograft injury: studies in swine-to-primate orthotopic single lung transplant models.
Transplantation 1998;65(8):1084-93.
1998: Shu S Lin; B C Weidner; Guerard W Byrne; Lisa E Diamond; Jeffrey H Lawson; Charles W Hoopes; Larkin J Daniels; Casey W Daggett; William Parker; robert harland; R Duane Davis; R Randal Bollinger; John S Logan; Jeffrey L Platt
The role of antibodies in acute vascular rejection of pig-to-baboon cardiac transplants.
The Journal of clinical investigation 1998;101(8):1745-56.
1998: William Parker; Zoie E Holzknecht; A Song; BA Blocher; Matilda Bustos; K J Reissner; Mary Lou Everett; Jeffrey L Platt
Fate of antigen in xenotransplantation: implications for acute vascular rejection and accommodation.
The American journal of pathology 1998;152(3):829-39.
1997: K R McCurry; William Parker; A H Cotterell; B C Weidner; Shu S Lin; Larkin J Daniels; Zoie E Holzknecht; Guerard W Byrne; Lisa E Diamond; John S Logan; Jeffrey L Platt
Humoral responses to pig-to-baboon cardiac transplantation: implications for the pathogenesis and treatment of acute vascular rejection and for accommodation.
Human immunology 1997;58(2):91-105.
1997: Shu S Lin; D L Kooyman; Larkin J Daniels; Casey W Daggett; William Parker; Jeffrey H Lawson; Charles W Hoopes; Carmelo Gullotto; L Li; P Birch; R Duane Davis; Lisa E Diamond; John S Logan; Jeffrey L Platt
The role of natural anti-Gal alpha 1-3Gal antibodies in hyperacute rejection of pig-to-baboon cardiac xenotransplants.
Transplant immunology 1997;5(3):212-8.
1997: William Parker; Paul Yu; Zoie E Holzknecht; K Lundberg; Rebecca H Buckley; Jeffrey L Platt
Specificity and function of "natural" antibodies in immunodeficient subjects: clues to B cell lineage and development.
Journal of clinical immunology 1997;17(4):311-21.
1996: Paul Yu; Zoie E Holzknecht; D Bruno; William Parker; Jeffrey L Platt
Modulation of natural IgM binding and complement activation by natural IgG antibodies: a role for IgG anti-Gal alpha1-3Gal antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(11):5163-8.
1996: William Parker; Soheyla Saadi; Shu S Lin; Zoie E Holzknecht; Matilda Bustos; Jeffrey L Platt
Transplantation of discordant xenografts: a challenge revisited.
Immunology today 1996;17(8):373-8.
1996: William Parker; J Lateef; Mary Lou Everett; Jeffrey L Platt
Specificity of xenoreactive anti-Gal alpha 1-3Gal IgM for alpha-galactosyl ligands.
Glycobiology 1996;6(5):499-506.
1996: Shu S Lin; Zoie E Holzknecht; William Parker; B J Lindman; Jeffrey L Platt
Porcine endothelial cell membrane antigens recognized by human and baboon xenoreactive antibodies during organ perfusion.
Transplantation proceedings 1996;28(2):607.
1996: Shu S Lin; William Parker; K Lundberg-Swanson; Z E Holtzknecht; Jeffrey L Platt
Xenoreactive natural antibodies and isohemagglutinins: a distinct class of antibodies.
Transplantation proceedings 1996;28(2):573.
1996: C G Alvarado; A H Cotterell; William Parker; John S Logan; Jeffrey L Platt
Variation in expression of biologically reactive xenoantigen does not correlate with expression of Gal alpha (1-3)Gal.
Transplantation proceedings 1996;28(2):555.
1996: William Parker; J Lateef; Mary Lou Everett; D Bruno; Jeffrey L Platt
Characterization of xenoreactive natural antibodies: interactions with carbohydrate determinants.
Transplantation proceedings 1996;28(2):548.
1996: A H Cotterell; B H Collins; William Parker; robert harland; Jeffrey L Platt
The humoral immune response in humans following ex vivo perfusion of porcine livers.
Transplantation proceedings 1996;28(2):546.
1996: D L Kooyman; S B McClellan; William Parker; P L Avissar; M A Velardo; Jeffrey L Platt; John S Logan
Identification and characterization of a galactosyl peptide mimetic. Implications for use in removing xenoreactive anti-A Gal antibodies.
Transplantation 1996;61(6):851-5.
1996: William Parker; K Lundberg-Swanson; Zoie E Holzknecht; J Lateef; S A Washburn; S J Braedehoeft; Jeffrey L Platt
Isohemagglutinins and xenoreactive antibodies: members of a distinct family of natural antibodies.
Human immunology 1996;45(2):94-104.
1995: Jeffrey L Platt; William Parker
Another step towards xenotransplantation.
Nature medicine 1995;1(12):1248-50.
1995: A H Cotterell; B H Collins; William Parker; robert harland; Jeffrey L Platt
The humoral immune response in humans following cross-perfusion of porcine organs.
Transplantation 1995;60(8):861-8.
1995: William Parker; D Bruno; Jeffrey L Platt
Xenoreactive natural antibodies in the world of natural antibodies: typical or unique?
Transplant immunology 1995;3(3):181-91.
1995: B H Collins; A H Cotterell; K R McCurry; C G Alvarado; John Magee; William Parker; Jeffrey L Platt
Cardiac xenografts between primate species provide evidence for the importance of the alpha-galactosyl determinant in hyperacute rejection.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(10):5500-10.
1994: William Parker; D Bruno; Zoie E Holzknecht; Jeffrey L Platt
Characterization and affinity isolation of xenoreactive human natural antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(8):3791-803.