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William Parker

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Eric J Sorscher; William R Waud; Paula W Allan; Jeong S Hong; William B Parker
In vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressing E. coli purine nucleoside phosphorylase.
Kajal Buckoreelall; Judith V Hobrath; Yanjie Sun; Landon Wilson; William B Parker
Identification of Rv0535 as methylthioadenosine phosphorylase from Mycobacterium tuberculosis.
William R Waud; Karen S Gilbert; William B Parker; John A Secrist
Isolation and characterization of a murine P388 leukemia line resistant to thiarabine.

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2012: Eric J Sorscher; William R Waud; Paula W Allan; Jeong S Hong; William B Parker
In vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressing E. coli purine nucleoside phosphorylase.
Cancer chemotherapy and pharmacology 2012;70(2):321-9.
2012: Kajal Buckoreelall; Judith V Hobrath; Yanjie Sun; Landon Wilson; William B Parker
Identification of Rv0535 as methylthioadenosine phosphorylase from Mycobacterium tuberculosis.
Tuberculosis (Edinburgh, Scotland) 2012;92(2):139-47.
2012: William R Waud; Karen S Gilbert; William B Parker; John A Secrist
Isolation and characterization of a murine P388 leukemia line resistant to thiarabine.
Nucleosides, nucleotides & nucleic acids 2012;31(1):14-27.
2012: Abdalla E A Hassan; Rashmi Khare; John A Montgomery; William B Parker; James M Riordan; Reham A I Abou-Elkhair; Paula W Allan; William R Waud; John A Secrist
Synthesis and evaluation of the substrate activity of C-6 substituted purine ribosides with E. coli purine nucleoside phosphorylase: palladium mediated cross-coupling of organozinc halides with 6-chloropurine nucleosides.
European journal of medicinal chemistry 2012;47(1):167-74.
2011: William R Waud; Karen S Gilbert; William B Parker; John A Secrist
Isolation and characterization of a murine P388 leukemia line resistant to clofarabine.
Nucleosides, nucleotides & nucleic acids 2011;30(11):826-38.
2011: Timothy H Tran; Paula W Allan; S Christoffersen; William B Parker; Jure Piskur; I Serra; M Terreni; Steven E Ealick
The crystal structure of Streptococcus pyogenes uridine phosphorylase reveals a distinct subfamily of nucleoside phosphorylases.
Biochemistry 2011;50(30):6549-58.
2011: William B Parker; Paula W Allan; William R Waud; J S Hong; Eric J Sorscher
Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase.
Cancer gene therapy 2011;18(6):390-8.
2010: You-Na Kang; Yang Zhang; Paula W Allan; William B Parker; Jing-Wen Ting; Chi-Yao Chang; Steven E Ealick
Structure of grouper iridovirus purine nucleoside phosphorylase.
Acta crystallographica. Section D, Biological crystallography 2010;66(Pt 2):155-62.
2009: Dong-Hoon Chung; J Jacob Strouse; Yanjie Sun; Jeffrey B Arterburn; William B Parker; Colleen B Jonsson
Synthesis and anti-Hantaan virus activity of N(1)-3-fluorophenyl-inosine.
Antiviral research 2009;83(1):80-5.
2009: William B Parker
Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer.
Chemical reviews 2009;109(7):2880-93.
2009: William B Parker; Sue C Shaddix; Karen S Gilbert; Rodney V Shepherd; William R Waud
Enhancement of the in vivo antitumor activity of clofarabine by 1-beta-D-[4-thio-arabinofuranosyl]-cytosine.
Cancer chemotherapy and pharmacology 2009;64(2):253-61.
2009: Kamal N Tiwari; AT Shortnacy-Fowler; William B Parker; William R Waud; John A Secrist
Synthesis and anticancer evaluation of 4'-C-methyl-2'-fluoro arabino nucleosides.
Nucleosides, nucleotides & nucleic acids 2009;28(5):657-77.
2009: Abdalla E A Hassan; William B Parker; Paula W Allan; John A Secrist
Regioselective metalation of 6-methylpurines: synthesis of fluoromethyl purines and related nucleosides for suicide gene therapy of cancer.
Nucleosides, nucleotides & nucleic acids 2009;28(5):642-56.
2008: Dong-Hoon Chung; Sidath C Kumarapperuma; Yanjie Sun; Qianjun Li; Yong-Kyu Chu; Jeffrey B Arterburn; William B Parker; Jeffrey Smith; Kristin Spik; Harish N Ramanathan; Connie S Schmaljohn; Colleen B Jonsson
Synthesis of 1-beta-D-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus.
Antiviral research 2008;79(1):19-27.
2008: Mary C Long; Sue C Shaddix; Omar Moukha-chafiq; Joseph A Maddry; Lisa Nagy; William B Parker
Structure-activity relationship for adenosine kinase from Mycobacterium tuberculosis II. Modifications to the ribofuranosyl moiety.
Biochemical pharmacology 2008;75(8):1588-600.
2007: Guy Ungerechts; Christoph Springfeld; Marie Frenzke; Johanna Lampe; Patrick B Johnston; William B Parker; Eric J Sorscher; Roberto Cattaneo
Lymphoma chemovirotherapy: CD20-targeted and convertase-armed measles virus can synergize with fludarabine.
Cancer research 2007;67(22):10939-47.
2007: Guy Ungerechts; Christoph Springfeld; Marie Frenzke; Johanna Lampe; William B Parker; Eric J Sorscher; Roberto Cattaneo
An immunocompetent murine model for oncolysis with an armed and targeted measles virus.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(11):1991-7.
2007: Dong-Hoon Chung; Yanjie Sun; William B Parker; Jeffrey B Arterburn; Alfred A Bartolucci; Colleen B Jonsson
Ribavirin reveals a lethal threshold of allowable mutation frequency for Hantaan virus.
Journal of virology 2007;81(21):11722-9.
2007: Sidath C Kumarapperuma; Yanjie Sun; Marjan Jeselnik; Kiwon Chung; William B Parker; Colleen B Jonsson; Jeffrey B Arterburn
Structural effects on the phosphorylation of 3-substituted 1-beta-D-ribofuranosyl-1,2,4-triazoles by human adenosine kinase.
Bioorganic & medicinal chemistry letters 2007;17(11):3203-7.
2007: William B Parker; Mary C Long
Purine metabolism in Mycobacterium tuberculosis as a target for drug development.
Current pharmaceutical design 2007;13(6):599-608.
2007: Mary C Long; Paula W Allan; Mei-Zhen Luo; Mao-Chin Liu; Alan C Sartorelli; William B Parker
Evaluation of 3-deaza-adenosine analogues as ligands for adenosine kinase and inhibitors of Mycobacterium tuberculosis growth.
The Journal of antimicrobial chemotherapy 2007;59(1):118-21.
2007: Yanjie Sun; Dong-Hoon Chung; Yong-Kyu Chu; Colleen B Jonsson; William B Parker
Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5'-triphosphate, not with inhibition of IMP dehydrogenase.
Antimicrobial agents and chemotherapy 2007;51(1):84-8.
2006: Anshu M Roy; Kamal N Tiwari; William B Parker; John A Secrist; Rongbao Li; Zhican Qu
Antiangiogenic activity of 4'-thio-beta-D-arabinofuranosylcytosine.
Molecular cancer therapeutics 2006;5(9):2218-24.
2006: Mary C Long; William B Parker
Structure-activity relationship for nucleoside analogs as inhibitors or substrates of adenosine kinase from Mycobacterium tuberculosis. I. Modifications to the adenine moiety.
Biochemical pharmacology 2006;71(12):1671-82.
2006: Hitoshi Someya; William R Waud; William B Parker
Long intracellular retention of 4'-thio-arabinofuranosylcytosine 5'-triphosphate as a critical factor for the anti-solid tumor activity of 4'-thio-arabinofuranosylcytosine.
Cancer chemotherapy and pharmacology 2006;57(6):772-80.
2006: Jaideep V Thottassery; Louise Westbrook; Hitoshi Someya; William B Parker
c-Abl-independent p73 stabilization during gemcitabine- or 4'-thio-beta-D-arabinofuranosylcytosine-induced apoptosis in wild-type and p53-null colorectal cancer cells.
Molecular cancer therapeutics 2006;5(2):400-10.
2005: Yimin Wang; Mary C Long; Senthil Ranganathan; Vincent Escuyer; William B Parker; Rongbao Li
Overexpression, purification and crystallographic analysis of a unique adenosine kinase from Mycobacterium tuberculosis.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 6):553-7.
2005: Suman Bharara; Eric J Sorscher; G Yancey Gillespie; J Russell Lindsey; Jeong S Hong; Kimberly V Curlee; Paula W Allan; Vijayakrishna K Gadi; Sherrie A Alexander; John A Secrist; William B Parker; William R Waud
Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy.
Human gene therapy 2005;16(3):339-47.
2005: William B Parker
Metabolism and antiviral activity of ribavirin.
Virus research 2005;107(2):165-71.
2005: Yang Zhang; William B Parker; Eric J Sorscher; Steven E Ealick
PNP anticancer gene therapy.
Current topics in medicinal chemistry 2005;5(13):1259-74.
2005: A V Silamkoti; Paula W Allan; Abdalla E A Hassan; Anita T Fowler; Eric J Sorscher; William B Parker; John A Secrist
Synthesis and biological activity of 2-fluoro adenine and 6-methyl purine nucleoside analogs as prodrugs for suicide gene therapy of cancer.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):881-5.
2005: J D Rose; William B Parker; John A Secrist
Bis(tBuSATE) phosphotriester prodrugs of 8-azaguanosine and 6-methylpurine riboside; bis(pom) phosphotriester prodrugs of 2'-deoxy-4'-thioadenosine and its corresponding 9alpha anomer.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):809-13.
2005: William B Parker; Paula W Allan; Steven E Ealick; Eric J Sorscher; Abdalla E A Hassan; A V Silamkoti; Anita T Fowler; William R Waud; John A Secrist
Design and evaluation of 5'-modified nucleoside analogs as prodrugs for an E. coli purine nucleoside phosphorylase mutant.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):387-92.
2004: Jeong S Hong; William R Waud; Dana Levasseur; Tim M Townes; Hui Wen; Sylvia A McPherson; Bryan A Moore; Zsuzsa Bebok; Paula W Allan; John A Secrist; William B Parker; Eric J Sorscher
Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene.
Cancer research 2004;64(18):6610-5.
2004: William B Parker; John A Secrist; William R Waud
Purine nucleoside antimetabolites in development for the treatment of cancer.
Current opinion in investigational drugs (London, England : 2000) 2004;5(6):592-6.
2004: William B Parker; Esther W Barrow; Paula W Allan; Sue C Shaddix; Mary C Long; William W Barrow; Namita Bansal; Joseph A Maddry
Metabolism of 2-methyladenosine in Mycobacterium tuberculosis.
Tuberculosis (Edinburgh, Scotland) 2004;84(5):327-36.
2004: Kimberly V Curlee; William B Parker; Eric J Sorscher
Tumor sensitization to purine analogs by E. coli PNP.
Methods in molecular medicine 2004;90():223-45.
2003: Eric M Bennett; Ruchi Anand; Paula W Allan; Abdalla E A Hassan; Jeong S Hong; Dana Levasseur; David T McPherson; William B Parker; John A Secrist; Eric J Sorscher; Tim M Townes; William R Waud; Steven E Ealick
Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chemistry & biology 2003;10(12):1173-81.
2003: Eric M Bennett; Chenglong Li; Paula W Allan; William B Parker; Steven E Ealick
Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
The Journal of biological chemistry 2003;278(47):47110-8.
2003: Mary C Long; Vincent Escuyer; William B Parker
Identification and characterization of a unique adenosine kinase from Mycobacterium tuberculosis.
Journal of bacteriology 2003;185(22):6548-55.
2003: Esther W Barrow; Louise Westbrook; Namita Bansal; William J Suling; Joseph A Maddry; William B Parker; William W Barrow
Antimycobacterial activity of 2-methyl-adenosine.
The Journal of antimicrobial chemotherapy 2003;52(5):801-8.
2003: Abdalla E A Hassan; William B Parker; Paula W Allan; John A Montgomery; John A Secrist
Selective metalation of 6-methylpurines: synthesis of 6-fluoromethylpurines and related nucleosides.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):747-9.
2003: Hitoshi Someya; Sue C Shaddix; Kamal N Tiwari; John A Secrist; William B Parker
Phosphorylation of 4'-thio-beta-D-arabinofuranosylcytosine and its analogs by human deoxycytidine kinase.
The Journal of pharmacology and experimental therapeutics 2003;304(3):1314-22.
2003: Vijayakrishna K Gadi; Sherrie D Alexander; William R Waud; Paula W Allan; William B Parker; Eric J Sorscher
A long-acting suicide gene toxin, 6-methylpurine, inhibits slow growing tumors after a single administration.
The Journal of pharmacology and experimental therapeutics 2003;304(3):1280-4.
2003: William B Parker; Paula W Allan; Abdalla E A Hassan; John A Secrist; Eric J Sorscher; William R Waud
Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase.
Cancer gene therapy 2003;10(1):23-9.
2002: Jerry D Rose; William B Parker; Hitoshi Someya; Sue C Shaddix; John A Montgomery; John A Secrist
Enhancement of nucleoside cytotoxicity through nucleotide prodrugs.
Journal of medicinal chemistry 2002;45(20):4505-12.
2002: Donna S Shewach; Patrick J Murphy; Blaine W Robinson; Jennifer L Vuletich; Paul D Boucher; Anna L Blobaum; Laura Zerbe; John A Secrist; William B Parker
Multi-log cytotoxicity of carbocyclic 2'-deoxyguanosine in HSV-TK-expressing human tumor cells.
Human gene therapy 2002;13(4):543-51.
2002: Chih-Kuang Chen; Esther W Barrow; Paula W Allan; Namita Bansal; Joseph A Maddry; William J Suling; William W Barrow; William B Parker
The metabolism of 2-methyladenosine in Mycobacterium smegmatis.
Microbiology (Reading, England) 2002;148(Pt 1):289-95.
2000: William B Parker; Sue C Shaddix; LM Rose; William R Waud; Donna S Shewach; Kamal N Tiwari; John A Secrist
Metabolism of 4'-thio-beta-D-arabinofuranosylcytosine in CEM cells.
Biochemical pharmacology 2000;60(12):1925-32.
2000: Kamal N Tiwari; AT Shortnacy-Fowler; Loredana Cappellacci; William R Waud; William B Parker; John A Montgomery; John A Secrist
Synthesis and structure activity relationships of 5-substituted-4'-thio-beta-D-arabinofuranosylcytosines.
Nucleosides, nucleotides & nucleic acids 2000;19(10-12):2005-17.
2000: Vijayakrishna K Gadi; S D Alexander; Jeffrey E Kudlow; Paula W Allan; William B Parker; Eric J Sorscher
In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells.
Gene therapy 2000;7(20):1738-43.
2000: William B Parker; Sue C Shaddix; LM Rose; P T Pham; M Hua; R Vince
Metabolism of O6-propyl and N6-propyl-carbovir in CEM cells.
Nucleosides, nucleotides & nucleic acids 2000;19(4):795-804.
2000: S W Tendian; William B Parker
Interaction of deoxyguanosine nucleotide analogs with human telomerase.
Molecular pharmacology 2000;57(4):695-9.
2000: Kamal N Tiwari; AT Shortnacy-Fowler; Loredana Cappellacci; William B Parker; William R Waud; John A Montgomery; John A Secrist
Synthesis of 4'-thio-beta-D-arabinofuranosylcytosine (4'-thio-ara-C) and comparison of its anticancer activity with that of ara-C.
Nucleosides, nucleotides & nucleic acids 2000;19(1-2):329-40.
1999: John A Secrist; William B Parker; Paula W Allan; LL Bennett; William R Waud; J W Truss; Anita T Fowler; John A Montgomery; Steven E Ealick; A H Wells; G Yancey Gillespie; Vijayakrishna K Gadi; Eric J Sorscher
Gene therapy of cancer: activation of nucleoside prodrugs with E. coli purine nucleoside phosphorylase.
Nucleosides & nucleotides 1999;18(4-5):745-57.
1999: William B Parker; Sue C Shaddix; LM Rose; Donna S Shewach; L W Hertel; John A Secrist; John A Montgomery; LL Bennett
Comparison of the mechanism of cytotoxicity of 2-chloro-9-(2-deoxy-2- fluoro-beta-D-arabinofuranosyl)adenine, 2-chloro-9-(2-deoxy-2-fluoro- beta-D-ribofuranosyl)adenine, and 2-chloro-9-(2-deoxy-2,2-difluoro- beta-D-ribofuranosyl)adenine in CEM cells.
Molecular pharmacology 1999;55(3):515-20.
1998: William B Parker; Paula W Allan; Sue C Shaddix; LM Rose; H F Speegle; G Yancey Gillespie; LL Bennett
Metabolism and metabolic actions of 6-methylpurine and 2-fluoroadenine in human cells.
Biochemical pharmacology 1998;55(10):1673-81.
1998: LL Bennett; Paula W Allan; G Arnett; Y F Shealy; Donna S Shewach; W S Mason; I Fourel; William B Parker
Metabolism in human cells of the D and L enantiomers of the carbocyclic analog of 2'-deoxyguanosine: substrate activity with deoxycytidine kinase, mitochondrial deoxyguanosine kinase, and 5'-nucleotidase.
Antimicrobial agents and chemotherapy 1998;42(5):1045-51.
1998: R A Weldon; William B Parker; Michael Sakalian; Eric Hunter
Type D retrovirus capsid assembly and release are active events requiring ATP.
Journal of virology 1998;72(4):3098-106.
1998: B W Hughes; Scott A King; Paula W Allan; William B Parker; Eric J Sorscher
Cell to cell contact is not required for bystander cell killing by Escherichia coli purine nucleoside phosphorylase.
The Journal of biological chemistry 1998;273(4):2322-8.
1997: William B Parker; Scott A King; Paula W Allan; LL Bennett; John A Secrist; John A Montgomery; K S Gilbert; William R Waud; A H Wells; G Yancey Gillespie; Eric J Sorscher
In vivo gene therapy of cancer with E. coli purine nucleoside phosphorylase.
Human gene therapy 1997;8(14):1637-44.
1997: William B Parker; Sue C Shaddix; R Vince; LL Bennett
Lack of mitochondrial toxicity in CEM cells treated with carbovir.
Antiviral research 1997;34(3):131-6.
1996: L Walker; Markku Kulomaa; Z Bebok; William B Parker; P Allan; J Logan; Z Huang; R C Reynolds; S King; Eric J Sorscher
Development of drug targeting based on recombinant expression of the chicken avidin gene.
Journal of drug targeting 1996;4(1):41-9.
1995: William B Parker; Sue C Shaddix; LM Rose; Kamal N Tiwari; J A Montogmery; John A Secrist; LL Bennett
Metabolism and metabolic actions of 4'-thiothymidine in L1210 cells.
Biochemical pharmacology 1995;50(5):687-95.
1995: B W Hughes; A H Wells; Z Bebok; Vijayakrishna K Gadi; Robert I Garver; William B Parker; Eric J Sorscher
Bystander killing of melanoma cells using the human tyrosinase promoter to express the Escherichia coli purine nucleoside phosphorylase gene.
Cancer research 1995;55(15):3339-45.
1995: J A Sandberg; Zbigniew K Binienda; G Lipe; LM Rose; William B Parker; Syed F Ali; William Slikker
Placental transfer and fetal disposition of 2',3'-dideoxycytidine and 2',3'-dideoxyinosine in the rhesus monkey.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(8):881-4.
1994: Eric J Sorscher; S Peng; Z Bebok; Paula W Allan; LL Bennett; William B Parker
Tumor cell bystander killing in colonic carcinoma utilizing the Escherichia coli DeoD gene to generate toxic purines.
Gene therapy 1994;1(4):233-8.
1994: William B Parker; Paula W Allan; S Niwas; J A Montgomery; LL Bennett
Effect of 9-benzyl-9-deazaguanine, a potent inhibitor of purine nucleoside phosphorylase, on the cytotoxicity and metabolism of 6-thio-2'-deoxyguanosine.
Cancer research 1994;54(7):1742-5.
1994: R D Elliott; G A Rener; J M Riordan; John A Secrist; LL Bennett; William B Parker; J A Montgomery
Phosphonate analogs of carbocyclic nucleotides.
Journal of medicinal chemistry 1994;37(6):739-44.
1993: LL Bennett; William B Parker; Paula W Allan; LM Rose; Y Fulmer Shealy; John A Secrist; J A Montgomery; G Arnett; R L Kirkman; W M Shannon
Phosphorylation of the enantiomers of the carbocyclic analog of 2'-deoxyguanosine in cells infected with herpes simplex virus type 1 and in uninfected cells. Lack of enantiomeric selectivity with the viral thymidine kinase.
Molecular pharmacology 1993;44(6):1258-66.
1993: E Lucile White; William B Parker; L J Ross; W M Shannon
Lack of synergy in the inhibition of HIV-1 reverse transcriptase by combinations of the 5'-triphosphates of various anti-HIV nucleoside analogs.
Antiviral research 1993;22(4):295-308.
1993: William B Parker; Sue C Shaddix; B J Bowdon; LM Rose; R Vince; W M Shannon; LL Bennett
Metabolism of carbovir, a potent inhibitor of human immunodeficiency virus type 1, and its effects on cellular metabolism.
Antimicrobial agents and chemotherapy 1993;37(5):1004-9.
1992: William B Parker; E Lucile White; Sue C Shaddix; L J Ross; W M Shannon; John A Secrist
Interference with HIV-1 reverse transcriptase-catalyzed DNA chain elongation by the 5'-triphosphate of the carbocyclic analog of 2'-deoxyguanosine.
Antiviral research 1992;19(4):325-32.
1992: William B Parker; Sue C Shaddix; Paula W Allan; G Arnett; LM Rose; W M Shannon; Y Fulmer Shealy; J A Montgomery; John A Secrist; LL Bennett
Incorporation of the carbocyclic analog of 2'-deoxyguanosine into the DNA of herpes simplex virus and of HEp-2 cells infected with herpes simplex virus.
Molecular pharmacology 1992;41(2):245-51.
1991: William B Parker; Sue C Shaddix; C H Chang; E Lucile White; LM Rose; R W Brockman; A T Shortnacy; J A Montgomery; John A Secrist; LL Bennett
Effects of 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate.
Cancer research 1991;51(9):2386-94.
1991: William B Parker; E Lucile White; Sue C Shaddix; L J Ross; Robert W Buckheit; J M Germany; John A Secrist; R Vince; W M Shannon
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs.
The Journal of biological chemistry 1991;266(3):1754-62.
1990: William B Parker; Y C Cheng
Metabolism and mechanism of action of 5-fluorouracil.
Pharmacology & therapeutics 1990;48(3):381-95.
1989: E Lucile White; William B Parker; L J Macy; Sue C Shaddix; G McCaleb; John A Secrist; R Vince; W M Shannon
Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases.
Biochemical and biophysical research communications 1989;161(2):393-8.