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Anna-Kaisa Parkkila

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Pei-wen Pan; Anna-Kaisa Parkkila; Salla Autio; Hannu Haapasalo; Mika Hilvo; Jaromir Pastorek; Silvia Pastorekova; Raija Sormunen; Seppo Parkkila
Brain phenotype of carbonic anhydrase IX-deficient mice.
Kristiina Nordfors; Joonas A Haapasalo; Miikka Korja; Anssi Niemelä; Jukka Laine; Anna-Kaisa Parkkila; Silvia Pastorekova; Jaromir Pastorek; Abdul Waheed; William S Sly; Seppo Parkkila; Hannu Haapasalo
The tumour-associated carbonic anhydrases CA II, CA IX and CA XII in a group of medulloblastomas and supratentorial primitive neuroectodermal tumours: an association of CA IX with poor prognosis.
Joonas Haapasalo; Mika Hilvo; Kristiina Nordfors; Hannu Haapasalo; Seppo Parkkila; Alise Hyrskyluoto; Immo Rantala; Abdul Waheed; William S Sly; Silvia Pastorekova; Jaromir Pastorek; Anna-Kaisa Parkkila
Identification of an alternatively spliced isoform of carbonic anhydrase XII in diffusely infiltrating astrocytic gliomas.

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All Publications

2012: Pei-wen Pan; Anna-Kaisa Parkkila; Salla Autio; Hannu Haapasalo; Mika Hilvo; Jaromir Pastorek; Silvia Pastorekova; Raija Sormunen; Seppo Parkkila
Brain phenotype of carbonic anhydrase IX-deficient mice.
Transgenic research 2012;21(1):163-76.
2010: Kristiina Nordfors; Joonas A Haapasalo; Miikka Korja; Anssi Niemelä; Jukka Laine; Anna-Kaisa Parkkila; Silvia Pastorekova; Jaromir Pastorek; Abdul Waheed; William S Sly; Seppo Parkkila; Hannu Haapasalo
The tumour-associated carbonic anhydrases CA II, CA IX and CA XII in a group of medulloblastomas and supratentorial primitive neuroectodermal tumours: an association of CA IX with poor prognosis.
BMC cancer 2010;10():148.
2008: Joonas Haapasalo; Mika Hilvo; Kristiina Nordfors; Hannu Haapasalo; Seppo Parkkila; Alise Hyrskyluoto; Immo Rantala; Abdul Waheed; William S Sly; Silvia Pastorekova; Jaromir Pastorek; Anna-Kaisa Parkkila
Identification of an alternatively spliced isoform of carbonic anhydrase XII in diffusely infiltrating astrocytic gliomas.
Neuro-oncology 2008;10(2):131-8.
2008: Sally Järvelä; Seppo Parkkila; Helena Bragge; Marketta Kähkönen; Anna-Kaisa Parkkila; Ylermi Soini; Silvia Pastorekova; Jaromir Pastorek; Hannu Haapasalo
Carbonic anhydrase IX in oligodendroglial brain tumors.
BMC cancer 2008;8():1.
2007: Anssi M Niemelä; Piritta Hynninen; Jukka-Pekka Mecklin; Teijo Kuopio; Antti Kokko; Lauri Aaltonen; Anna-Kaisa Parkkila; Silvia Pastorekova; Jaromir Pastorek; Abdul Waheed; William S Sly; Torben F Orntoft; Mogens Kruhøffer; Hannu Haapasalo; Seppo Parkkila; Aarre Kivelä
Carbonic anhydrase IX is highly expressed in hereditary nonpolyposis colorectal cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(9):1760-6.
2007: Joonas Haapasalo; Kristiina Nordfors; Sally Järvelä; Helena Bragge; Immo Rantala; Anna-Kaisa Parkkila; Hannu Haapasalo; Seppo Parkkila
Carbonic anhydrase II in the endothelium of glial tumors: a potential target for therapy.
Neuro-oncology 2007;9(3):308-13.
2006: Seppo Parkkila; Daniela Vullo; Luca Puccetti; Anna-Kaisa Parkkila; Andrea Scozzafava; Claudiu T Supuran
Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines.
Bioorganic & medicinal chemistry letters 2006;16(15):3955-9.
2006: Joonas A Haapasalo; Kristiina M Nordfors; Mika Hilvo; Immo J Rantala; Ylermi Soini; Anna-Kaisa Parkkila; Silvia Pastoreková; Jaromir Pastorek; Seppo Parkkila; Hannu Haapasalo
Expression of carbonic anhydrase IX in astrocytic tumors predicts poor prognosis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(2):473-7.
2005: Antti-J Kivela; Seppo Parkkila; Juha Saarnio; Tuomo J Karttunen; Jyrki Kivela; Anna-Kaisa Parkkila; Maria Bartosova; Vojtech Mucha; Michal Novak; Abdul Waheed; William S Sly; Hannu J Rajaniemi; Silvia Pastorekova; Jaromir Pastorek
Expression of von Hippel-Lindau tumor suppressor and tumor-associated carbonic anhydrases IX and XII in normal and neoplastic colorectal mucosa.
World journal of gastroenterology : WJG 2005;11(17):2616-25.
2004: Jonna Lehtonen; bairong shen; Mauno Vihinen; Angela Casini; Andrea Scozzafava; Claudiu T Supuran; Anna-Kaisa Parkkila; Juha Saarnio; Aarre Kivelä; Abdul Waheed; William S Sly; Seppo Parkkila
Characterization of CA XIII, a novel member of the carbonic anhydrase isozyme family.
The Journal of biological chemistry 2004;279(4):2719-27.
2003: Miriam Zat'ovicová; Kvetoslava Tarábková; Eliska Svastová; Adriana Gibadulinová; Vojtech Mucha; Lýdia Jakubícková; Zuzana Biesová; Monika Rafajová; Marta Ortova Gut; Seppo Parkkila; Anna-Kaisa Parkkila; Abdul Waheed; Willam S Sly; Ivan Horak; Jaromir Pastorek; Silvia Pastoreková
Monoclonal antibodies generated in carbonic anhydrase IX-deficient mice recognize different domains of tumour-associated hypoxia-induced carbonic anhydrase IX.
Journal of immunological methods 2003;282(1-2):117-34.
2003: Jokke Hannuksela; Onni Niemelä; Mari Leppilampi; Anna-Kaisa Parkkila; Pirjo Koistinen; Pentti Nieminen; Seppo Parkkila
Clinical utility and outcome of HFE-genotyping in the search for hereditary hemochromatosis.
Clinica chimica acta; international journal of clinical chemistry 2003;331(1-2):61-7.
2002: Mari Leppilampi; Pirjo Koistinen; Eeva-Riitta Savolainen; Jokke Hannuksela; Anna-Kaisa Parkkila; Onni Niemelä; Silvia Pastoreková; Jaromir Pastorek; Abdul Waheed; William S Sly; Seppo Parkkila; Hannu J Rajaniemi
The expression of carbonic anhydrase II in hematological malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2240-5.
2002: Seppo Parkkila; Aarre Kivelä; Kari Kaunisto; Anna-Kaisa Parkkila; Jukka Hakkola; Hannu J Rajaniemi; Abdul Waheed; William S Sly
The plasma membrane carbonic anhydrase in murine hepatocytes identified as isozyme XIV.
BMC gastroenterology 2002;2():13.
2001: Juha Saarnio; Seppo Parkkila; Anna-Kaisa Parkkila; Silvia Pastoreková; Kari Haukipuro; Jaromir Pastorek; Tatu Juvonen; Tuomo J Karttunen
Transmembrane carbonic anhydrase, MN/CA IX, is a potential biomarker for biliary tumours.
Journal of hepatology 2001;35(5):643-9.
2001: A J Kivela; Juha Saarnio; Tuomo J Karttunen; Jyrki J. Kivelä; Anna-Kaisa Parkkila; Silvia Pastorekova; Jaromir Pastorek; Abdul Waheed; William S Sly; T S Parkkila; Hannu J Rajaniemi
Differential expression of cytoplasmic carbonic anhydrases, CA I and II, and membrane-associated isozymes, CA IX and XII, in normal mucosa of large intestine and in colorectal tumors.
Digestive diseases and sciences 2001;46(10):2179-86.
2001: Seppo Parkkila; Anna-Kaisa Parkkila; Hannu J Rajaniemi; Gul N Shah; Jeffrey H Grubb; Abdul Waheed; William S Sly
Expression of membrane-associated carbonic anhydrase XIV on neurons and axons in mouse and human brain.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1918-23.
2000: Seppo Parkkila; Anna-Kaisa Parkkila; Juha Saarnio; Jyrki J. Kivelä; Tuomo J Karttunen; Kari Kaunisto; Abdul Waheed; William S Sly; Ozlem Türeci; Ismo Virtanen; Hannu J Rajaniemi
Expression of the membrane-associated carbonic anhydrase isozyme XII in the human kidney and renal tumors.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2000;48(12):1601-8.
2000: Aarre Kivelä; Seppo Parkkila; Juha Saarnio; Tuomo J Karttunen; Jyrki J. Kivelä; Anna-Kaisa Parkkila; Silvia Pastoreková; Jaromir Pastorek; Abdul Waheed; William S Sly; Hannu J Rajaniemi
Expression of transmembrane carbonic anhydrase isoenzymes IX and XII in normal human pancreas and pancreatic tumours.
Histochemistry and cell biology 2000;114(3):197-204.
2000: P Karhumaa; Seppo Parkkila; Abdul Waheed; Anna-Kaisa Parkkila; Kari Kaunisto; P W Tucker; C J Huang; William S Sly; Hannu J Rajaniemi
Nuclear NonO/p54(nrb) protein is a nonclassical carbonic anhydrase.
The Journal of biological chemistry 2000;275(21):16044-9.
2000: Seppo Parkkila; Anna-Kaisa Parkkila; Abdul Waheed; Robert S Britton; X Y Zhou; Robert E Fleming; Shunji Tomatsu; Bruce R Bacon; William S Sly
Cell surface expression of HFE protein in epithelial cells, macrophages, and monocytes.
Haematologica 2000;85(4):340-5.
2000: Seppo Parkkila; Hannu J Rajaniemi; Anna-Kaisa Parkkila; Jyrki Kivela; Abdul Waheed; Silvia Pastorekova; Jaromir Pastorek; William S Sly
Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(5):2220-4.
2000: Aarre Kivelä; Seppo Parkkila; Juha Saarnio; Tuomo J Karttunen; Jyrki J. Kivelä; Anna-Kaisa Parkkila; Abdul Waheed; William S Sly; Jeffrey H Grubb; G Shah; Ozlem Türeci; Hannu J Rajaniemi
Expression of a novel transmembrane carbonic anhydrase isozyme XII in normal human gut and colorectal tumors.
The American journal of pathology 2000;156(2):577-84.
2000: Jyrki J. Kivelä; Seppo Parkkila; Anna-Kaisa Parkkila; Hannu J Rajaniemi
[Carbonic anhydrases protect teeth and upper gastrointestinal mucosa].
Duodecim; lääketieteellinen aikakauskirja 2000;116(19):2105-9.
2000: P Karhumaa; Seppo Parkkila; Ozlem Türeci; Abdul Waheed; Jeffrey H Grubb; G Shah; Anna-Kaisa Parkkila; Kari Kaunisto; Juha S Tapanainen; William S Sly; Hannu J Rajaniemi
Identification of carbonic anhydrase XII as the membrane isozyme expressed in the normal human endometrial epithelium.
Molecular human reproduction 2000;6(1):68-74.
1999: Jyrki Kivela; Seppo Parkkila; Anna-Kaisa Parkkila; Jukka S Leinonen; Hannu J Rajaniemi
Salivary carbonic anhydrase isoenzyme VI.
The Journal of physiology 1999;520 Pt 2():315-20.
1999: Jukka S Leinonen; Jyrki J. Kivelä; Seppo Parkkila; Anna-Kaisa Parkkila; Hannu J Rajaniemi
Salivary carbonic anhydrase isoenzyme VI is located in the human enamel pellicle.
Caries research 1999;33(3):185-90.
1999: Jyrki J. Kivelä; Seppo Parkkila; Anna-Kaisa Parkkila; Hannu J Rajaniemi
A low concentration of carbonic anhydrase isoenzyme VI in whole saliva is associated with caries prevalence.
Caries research 1999;33(3):178-84.
1999: Juha Saarnio; Seppo Parkkila; Anna-Kaisa Parkkila; Abdul Waheed; Tuomo J Karttunen; William S Sly
Cell-specific expression of mitochondrial carbonic anhydrase in the human and rat gastrointestinal tract.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1999;47(4):517-24.
1998: Juha Saarnio; Seppo Parkkila; Anna-Kaisa Parkkila; Kari Haukipuro; Silvia Pastoreková; Jaromir Pastorek; MI Kairaluoma; Tuomo J Karttunen
Immunohistochemical study of colorectal tumors for expression of a novel transmembrane carbonic anhydrase, MN/CA IX, with potential value as a marker of cell proliferation.
The American journal of pathology 1998;153(1):279-85.
1998: Ozlem Türeci; Ugur Sahin; E Vollmar; S Siemer; E Göttert; G Seitz; Anna-Kaisa Parkkila; Gul N Shah; Jeffrey H Grubb; Michael Pfreundschuh; William S Sly
Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7608-13.
1998: Juha Saarnio; Seppo Parkkila; Anna-Kaisa Parkkila; Abdul Waheed; M C Casey; X Y Zhou; Silvia Pastoreková; Jaromir Pastorek; Tuomo J Karttunen; Kari Haukipuro; MI Kairaluoma; William S Sly
Immunohistochemistry of carbonic anhydrase isozyme IX (MN/CA IX) in human gut reveals polarized expression in the epithelial cells with the highest proliferative capacity.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(4):497-504.
1997: Jyrki J. Kivelä; Seppo Parkkila; Abdul Waheed; Anna-Kaisa Parkkila; William S Sly; Hannu J Rajaniemi
Secretory carbonic anhydrase isoenzyme (CA VI) in human serum.
Clinical chemistry 1997;43(12):2318-22.
1997: Jyrki J. Kivelä; Seppo Parkkila; J Metteri; Anna-Kaisa Parkkila; A Toivanen; Hannu J Rajaniemi
Salivary carbonic anhydrase VI concentration and its relation to basic characteristics of saliva in young men.
Acta physiologica Scandinavica 1997;161(2):221-5.
1997: Anna-Kaisa Parkkila; Seppo Parkkila; M Reunanen; Onni Niemelä; Seppo Tuisku; I Rautakorpi; Hannu J Rajaniemi
Carbonic anhydrase II in the cerebrospinal fluid: its value as a disease marker.
European journal of clinical investigation 1997;27(5):392-7.
1997: Seppo Parkkila; Anna-Kaisa Parkkila; Juhani Lehtola; A Reinilä; H J Södervik; M Rannisto; Hannu J Rajaniemi
Salivary carbonic anhydrase protects gastroesophageal mucosa from acid injury.
Digestive diseases and sciences 1997;42(5):1013-9.
1997: Silvia Pastoreková; Seppo Parkkila; Anna-Kaisa Parkkila; R Opavský; Vladimír Zelník; Juha Saarnio; Jaromir Pastorek
Carbonic anhydrase IX, MN/CA IX: analysis of stomach complementary DNA sequence and expression in human and rat alimentary tracts.
Gastroenterology 1997;112(2):398-408.
1996: S Parkkila; Anna-Kaisa Parkkila; Tatu Juvonen; Abdul Waheed; William S Sly; Juha Saarnio; K Kaunisto; Sakari Kellokumpu; Hannu J Rajaniemi
Membrane-bound carbonic anhydrase IV is expressed in the luminal plasma membrane of the human gallbladder epithelium.
Hepatology (Baltimore, Md.) 1996;24(5):1104-8.
1996: S Parkkila; Anna-Kaisa Parkkila
Carbonic anhydrase in the alimentary tract. Roles of the different isozymes and salivary factors in the maintenance of optimal conditions in the gastrointestinal canal.
Scandinavian journal of gastroenterology 1996;31(4):305-17.
1996: Anna-Kaisa Parkkila; S Parkkila; Hannu J Rajaniemi
Carbonic anhydrase isoenzyme II is located in corticotrophs of the human pituitary gland.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1996;44(3):245-50.
1996: S Parkkila; Anna-Kaisa Parkkila
[ Gastrointestinal carbonic anhydrases].
Duodecim; lääketieteellinen aikakauskirja 1996;112(24):2383-8.
1995: Anna-Kaisa Parkkila; R Herva; S Parkkila; Hannu J Rajaniemi
Immunohistochemical demonstration of human carbonic anhydrase isoenzyme II in brain tumours.
The Histochemical journal 1995;27(12):974-82.
1995: Robert E Fleming; S Parkkila; Anna-Kaisa Parkkila; Hannu J Rajaniemi; Abdul Waheed; William S Sly
Carbonic anhydrase IV expression in rat and human gastrointestinal tract regional, cellular, and subcellular localization.
The Journal of clinical investigation 1995;96(6):2907-13.
1995: K Kaunisto; S Parkkila; Anna-Kaisa Parkkila; Abdul Waheed; William S Sly; Hannu J Rajaniemi
Expression of carbonic anhydrase isoenzymes IV and II in rat epididymal duct.
Biology of reproduction 1995;52(6):1350-7.
1995: S Parkkila; Anna-Kaisa Parkkila; Hannu J Rajaniemi
Circadian periodicity in salivary carbonic anhydrase VI concentration.
Acta physiologica Scandinavica 1995;154(2):205-11.
1995: S Parkkila; Anna-Kaisa Parkkila; Tatu Juvonen; V P Lehto; Hannu J Rajaniemi
Immunohistochemical demonstration of the carbonic anhydrase isoenzymes I and II in pancreatic tumours.
The Histochemical journal 1995;27(2):133-8.
1994: Anna-Kaisa Parkkila; S Parkkila; W Serlo; M Reunanen; T Vierjoki; Hannu J Rajaniemi
A competitive dual-label time-resolved immunofluorometric assay for simultaneous detection of carbonic anhydrase I and II in cerebrospinal fluid.
Clinica chimica acta; international journal of clinical chemistry 1994;230(1):81-9.
1994: Tatu Juvonen; S Parkkila; Anna-Kaisa Parkkila; Onni Niemelä; L H Lajunen; MI Kairaluoma; P Perämäki; Hannu J Rajaniemi
High-activity carbonic anhydrase isoenzyme (CA II) in human gallbladder epithelium.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1994;42(10):1393-7.
1994: S Parkkila; Anna-Kaisa Parkkila; Tatu Juvonen; Hannu J Rajaniemi
Distribution of the carbonic anhydrase isoenzymes I, II, and VI in the human alimentary tract.
Gut 1994;35(5):646-50.
1993: S Parkkila; Anna-Kaisa Parkkila; T Vierjoki; T Ståhlberg; Hannu J Rajaniemi
Competitive time-resolved immunofluorometric assay for quantifying carbonic anhydrase VI in saliva.
Clinical chemistry 1993;39(10):2154-7.
1993: S Parkkila; Anna-Kaisa Parkkila; K Kaunisto; Abdul Waheed; William S Sly; Hannu J Rajaniemi
Location of a membrane-bound carbonic anhydrase isoenzyme (CA IV) in the human male reproductive tract.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1993;41(5):751-7.
1993: Anna-Kaisa Parkkila; S Parkkila; Tatu Juvonen; Hannu J Rajaniemi
Carbonic anhydrase isoenzymes II and I are present in the zona glomerulosa cells of the human adrenal gland.
Histochemistry 1993;99(1):37-41.