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Maia Parsadanian

Research Profile

Chemicals & Drugs

Living Beings

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Anatomy

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Enzyme-Linked Immunosorbent Assay

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Publications

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Kristin R Wildsmith; Chengjie Xiong; Kevin E Yarasheski; Hyejin Yoon; Jacob Basak; Alison Goate; David M Holtzman; Hong Jiang; Tom Kasten; Jungsu Kim; Kwasi G Mawuenyega; Maia Parsadanian; Bruce W Patterson; Yuriy Pyatkivskyy; Wendy C Sigurdson; Jennifer X Wang; Randall Bateman
In vivo human apolipoprotein E isoform fractional turnover rates in the CNS.
Jacob Basak; Randall J Bateman; Hong Jiang; Jungsu Kim; Maia Parsadanian; Bruce W Patterson; Yuriy Pyatkivskyy; Kristin R Wildsmith; David M Holtzman
Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling.
Jungsu Kim; Joseph M Castellano; Hong Jiang; Jacob Basak; Maia Parsadanian; Vi Pham; Stephanie M Mason; Steven M Paul; David M Holtzman
Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.

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All Publications

2012: Kristin R Wildsmith; Chengjie Xiong; Kevin E Yarasheski; Hyejin Yoon; Jacob Basak; Alison Goate; David M Holtzman; Hong Jiang; Tom Kasten; Jungsu Kim; Kwasi G Mawuenyega; Maia Parsadanian; Bruce W Patterson; Yuriy Pyatkivskyy; Wendy C Sigurdson; Jennifer X Wang; Randall Bateman
In vivo human apolipoprotein E isoform fractional turnover rates in the CNS.
PloS one 2012;7(6):e38013.
2012: Jacob Basak; Randall J Bateman; Hong Jiang; Jungsu Kim; Maia Parsadanian; Bruce W Patterson; Yuriy Pyatkivskyy; Kristin R Wildsmith; David M Holtzman
Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling.
Molecular neurodegeneration 2012;7():14.
2009: Jungsu Kim; Joseph M Castellano; Hong Jiang; Jacob Basak; Maia Parsadanian; Vi Pham; Stephanie M Mason; Steven M Paul; David M Holtzman
Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.
Neuron 2009;64(5):632-44.
2008: Suzanne E Wahrle; Hong Jiang; Maia Parsadanian; Jungsu Kim; Aimin Li; Amanda Knoten; Sanjay Jain; Veronica Hirsch-Reinshagen; Cheryl L Wellington; Kelly R Bales; Steven M Paul; David M Holtzman
Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.
The Journal of clinical investigation 2008;118(2):671-82.
2007: David L Brody; Christine L Mac Donald; Chad C Kessens; Carla Yuede; Maia Parsadanian; Mike Spinner; Eddie Kim; Katherine E Schwetye; David M Holtzman; Philip V Bayly
Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injury.
Journal of neurotrauma 2007;24(4):657-73.
2006: Richard Hartman; Aartie Shah; Anne M Fagan; Katherine E Schwetye; Maia Parsadanian; Risa N Schulman; Mary Beth Finn; David M Holtzman
Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease.
Neurobiology of disease 2006;24(3):506-15.
2005: Suzanne E Wahrle; Hong Jiang; Maia Parsadanian; Richard Hartman; Kelly R Bales; Steven M Paul; David M Holtzman
Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease.
The Journal of biological chemistry 2005;280(52):43236-42.
2005: John R Cirrito; Rashid Deane; Anne M Fagan; Michael L Spinner; Maia Parsadanian; Mary Beth Finn; Hong Jiang; Julie L Prior; Abhay Sagare; Kelly R Bales; Steven M Paul; Berislav V Zlokovic; David Piwnica-Worms; David M Holtzman
P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model.
The Journal of clinical investigation 2005;115(11):3285-90.
2005: John D Fryer; Ronald B DeMattos; Lynn M McCormick; Mark A O'Dell; Michael L Spinner; Kelly R Bales; Steven M Paul; Patrick M. Sullivan; Maia Parsadanian; Guojun Bu; David M Holtzman
The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice.
The Journal of biological chemistry 2005;280(27):25754-9.
2005: John D Fryer; Kelly Simmons; Maia Parsadanian; Kelly R Bales; Steven M Paul; Patrick M. Sullivan; David M Holtzman
Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(11):2803-10.
2004: Anne M Fagan; Erin Christopher; Jennie W Taylor; Maia Parsadanian; Michael L Spinner; Melanie Watson; John D Fryer; Suzanne E Wahrle; Kelly R Bales; Steven M Paul; David M Holtzman
ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis.
The American journal of pathology 2004;165(4):1413-22.
2004: Suzanne E Wahrle; Hong Jiang; Maia Parsadanian; Justin Legleiter; Xianlin Han; John D Fryer; Tomasz Kowalewski; David M Holtzman
ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.
The Journal of biological chemistry 2004;279(39):40987-93.
2004: Ronald B DeMattos; John R Cirrito; Maia Parsadanian; Patrick May; Mark A O'Dell; Jennie W Taylor; Judith A K Harmony; Bruce Aronow; Kelly R Bales; Steven M Paul; David M Holtzman
ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.
Neuron 2004;41(2):193-202.
2003: John R Cirrito; Patrick May; Mark A O'Dell; Jennie W Taylor; Maia Parsadanian; Jeffrey W Cramer; James E Audia; Jeffrey S Nissen; Kelly R Bales; Steven M Paul; Ronald B DeMattos; David M Holtzman
In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-beta metabolism and half-life.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(26):8844-53.
2003: John D Fryer; Jennie W Taylor; Ronald B DeMattos; Kelly R Bales; Steven M Paul; Maia Parsadanian; David M Holtzman
Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(21):7889-96.
2002: Ronald B DeMattos; Mark A O'Dell; Maia Parsadanian; Jennie W Taylor; Judith A K Harmony; Kelly R Bales; Steven M Paul; Bruce Aronow; David M Holtzman
Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10843-8.
2002: Ronald B DeMattos; Kelly R Bales; Maia Parsadanian; Mark A O'Dell; Eric M Foss; Steven M Paul; David M Holtzman
Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.
Journal of neurochemistry 2002;81(2):229-36.
2002: Anne M Fagan; Melanie Watson; Maia Parsadanian; Kelly R Bales; Steven M Paul; David M Holtzman
Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.
Neurobiology of disease 2002;9(3):305-18.
2001: M E Gibson; Byung Hee Han; Junjeong Choi; CM Knudson; SJ Korsmeyer; Maia Parsadanian; David M Holtzman
BAX contributes to apoptotic-like death following neonatal hypoxia-ischemia: evidence for distinct apoptosis pathways.
Molecular medicine (Cambridge, Mass.) 2001;7(9):644-55.
2000: David M Holtzman; Kelly R Bales; T Tenkova; Anne M Fagan; Maia Parsadanian; L J Sartorius; B Mackey; John W Olney; Daniel W McKeel; D Wozniak; Steven M Paul
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2892-7.
2000: Byung Hee Han; A D'Costa; Stephen A Back; Maia Parsadanian; S Patel; Aarti R Shah; Jeffrey M Gidday; A Srinivasan; Mohanish Deshmukh; David M Holtzman
BDNF blocks caspase-3 activation in neonatal hypoxia-ischemia.
Neurobiology of disease 2000;7(1):38-53.
1999: David M Holtzman; Kelly R Bales; S Wu; P Bhat; Maia Parsadanian; Anne M Fagan; L K Chang; Y Sun; Steven M Paul
Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease.
The Journal of clinical investigation 1999;103(6):R15-R21.