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Richard Agnes

Research Profile

Chemicals & Drugs

Anatomy

Living Beings

Phenomena

Muscle Contraction

Genes & Molecular Sequences

Molecular Structure

Disorders

Neuralgia

Co-author Network

Publications

TOP 3
Katherine E Hanlon; Dave S Herman; Richard S Agnes; Tally M Largent-Milnes; Isuru R Kumarasinghe; Shou-wu Ma; Wenhong Guo; Yeon-Sun Lee; Michael H Ossipov; Victor J Hruby; Josephine Lai; Frank Porreca; Todd W Vanderah
Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain.
Wenjun Zhang; Shannon Gardell; Dongqin Zhang; Jennifer Y Xie; Richard S Agnes; Hamid Badghisi; Victor J Hruby; Naomi Rance; Michael H Ossipov; Todd W Vanderah; Frank Porreca; Josephine Lai
Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors.
Richard S Agnes; Jinfa Ying; Katalin E Kövér; Yeon Sun Lee; Peg Davis; Shou-wu Ma; Hamid Badghisi; Frank Porreca; Josephine Lai; Victor J Hruby
Structure-activity relationships of bifunctional cyclic disulfide peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors.

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All Publications

2011: Katherine E Hanlon; Dave S Herman; Richard S Agnes; Tally M Largent-Milnes; Isuru R Kumarasinghe; Shou-wu Ma; Wenhong Guo; Yeon-Sun Lee; Michael H Ossipov; Victor J Hruby; Josephine Lai; Frank Porreca; Todd W Vanderah
Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain.
Brain research 2011;1395():1-11.
2009: Wenjun Zhang; Shannon Gardell; Dongqin Zhang; Jennifer Y Xie; Richard S Agnes; Hamid Badghisi; Victor J Hruby; Naomi Rance; Michael H Ossipov; Todd W Vanderah; Frank Porreca; Josephine Lai
Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors.
Brain : a journal of neurology 2009;132(Pt 3):778-87.
2008: Richard S Agnes; Jinfa Ying; Katalin E Kövér; Yeon Sun Lee; Peg Davis; Shou-wu Ma; Hamid Badghisi; Frank Porreca; Josephine Lai; Victor J Hruby
Structure-activity relationships of bifunctional cyclic disulfide peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors.
Peptides 2008;29(8):1413-23.
2008: Yeon Sun Lee; Richard S Agnes; James P Cain; Vinod Kulkarni; Minying Cai; Christine Salibay; Kathy Ciano; Ravil R Petrov; Alexander V Mayorov; Josef Vagner; Dev Trivedi; Peg Davis; Shou-wu Ma; Josephine Lai; Frank Porreca; Ruben Vardanyan; Victor J Hruby
Opioid and melanocortin receptors: do they have overlapping pharmacophores?
Biopolymers 2008;90(3):433-8.
2007: Yeon Sun Lee; Joel Nyberg; Sharif Moye; Richard S Agnes; Peg Davis; Shou-wu Ma; Josephine Lai; Frank Porreca; Ruben Vardanyan; Victor J Hruby
Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at mu and delta opioid receptors.
Bioorganic & medicinal chemistry letters 2007;17(8):2161-5.
2007: Yeon Sun Lee; Richard S Agnes; Peg Davis; Shou-wu Ma; Hamid Badghisi; Josephine Lai; Frank Porreca; Victor J Hruby
Partial retro-inverso, retro, and inverso modifications of hydrazide linked bifunctional peptides for opioid and cholecystokinin (CCK) receptors.
Journal of medicinal chemistry 2007;50(1):165-8.
2006: Richard S Agnes; Yeon Sun Lee; Peg Davis; Shou-wu Ma; Hamid Badghisi; Frank Porreca; Josephine Lai; Victor J Hruby
Structure-activity relationships of bifunctional peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors.
Journal of medicinal chemistry 2006;49(10):2868-75.
2006: Yeon Sun Lee; Richard S Agnes; Hamid Badghisi; Peg Davis; Shou-wu Ma; Josephine Lai; Frank Porreca; Victor J Hruby
Design and synthesis of novel hydrazide-linked bifunctional peptides as delta/mu opioid receptor agonists and CCK-1/CCK-2 receptor antagonists.
Journal of medicinal chemistry 2006;49(5):1773-80.
2006: Victor J Hruby; Frank Porreca; Henry I Yamamura; Gordon Tollin; Richard S Agnes; Yeon Sun Lee; Minying Cai; Isabel D Alves; Scott M Cowell; Eva Varga; Peg Davis; Zdzislaw Salamon; William R Roeske; Todd W Vanderah; Josephine Lai
New paradigms and tools in drug design for pain and addiction.
The AAPS journal 2006;8(3):E450-60.
2004: Xuyuan Gu; Jinfa Ying; Richard S Agnes; Edita Navratilova; Peg Davis; Gannon Stahl; Frank Porreca; Henry I Yamamura; Victor J Hruby
Novel design of bicyclic beta-turn dipeptides on solid-phase supports and synthesis of [3.3.0]-Bicyclo([2,3])-leu-enkephalin analogues.
Organic letters 2004;6(19):3285-8.
2003: Victor J Hruby; Richard S Agnes; Peg Davis; Shou-wu Ma; Yeon Sun Lee; Todd W Vanderah; Josephine Lai; Frank Porreca
Design of novel peptide ligands which have opioid agonist activity and CCK antagonist activity for the treatment of pain.
Life sciences 2003;73(6):699-704.
2002: Victor J Hruby; Richard S Agnes; Chaozhong Cai
Design of peptide agonists.
Methods in enzymology 2002;343():73-91.
1999: Victor J Hruby; Richard S Agnes
Conformation-activity relationships of opioid peptides with selective activities at opioid receptors.
Biopolymers 1999;51(6):391-410.