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Eleftherios Paschalis

Research Profile

Procedures

Concepts & Ideas

Bone Density

Physiology

Anatomy

Chemicals & Drugs

Disorders

Living Beings

Mouse

Phenomena

Spectrum Analysis, Raman

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Publications

TOP 3
Roman Thaler; Jochen Zwerina; Sonja Gamsjaeger; Klaus Klaushofer; Eleftherios P Paschalis; Monika Rumpler; Silvia Spitzer; Franz Varga
Homocysteine induces serum amyloid A3 in osteoblasts via unlocking RGD-motifs in collagen.
Eleftherios P Paschalis; Roger Phipps; S Robins; A Roschger; Adele L Boskey; B Buchinger; Enrico Dall'Ara; Peter Fratzl; Sonja Gamsjaeger; Klaus Klaushofer; Inderchand Manjubala; D N Tatakis; Peter Varga; R Zoehrer; Philippe K Zysset; Paul Roschger
Lathyrism-induced alterations in collagen cross-links influence the mechanical properties of bone material without affecting the mineral.
Sonja Gamsjaeger; Klaus Klaushofer; Roger Phipps; Ruth Zoehrer; Birgit Buchinger; Eleftherios P Paschalis
Effects of one year daily teriparatide treatment on trabecular bone material properties in postmenopausal osteoporotic women previously treated with alendronate or risedronate.

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All Publications

2013: Roman Thaler; Jochen Zwerina; Sonja Gamsjaeger; Klaus Klaushofer; Eleftherios P Paschalis; Monika Rumpler; Silvia Spitzer; Franz Varga
Homocysteine induces serum amyloid A3 in osteoblasts via unlocking RGD-motifs in collagen.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013;27(2):446-63.
2011: Eleftherios P Paschalis; Roger Phipps; S Robins; A Roschger; Adele L Boskey; B Buchinger; Enrico Dall'Ara; Peter Fratzl; Sonja Gamsjaeger; Klaus Klaushofer; Inderchand Manjubala; D N Tatakis; Peter Varga; R Zoehrer; Philippe K Zysset; Paul Roschger
Lathyrism-induced alterations in collagen cross-links influence the mechanical properties of bone material without affecting the mineral.
Bone 2011;49(6):1232-41.
2011: Sonja Gamsjaeger; Klaus Klaushofer; Roger Phipps; Ruth Zoehrer; Birgit Buchinger; Eleftherios P Paschalis
Effects of one year daily teriparatide treatment on trabecular bone material properties in postmenopausal osteoporotic women previously treated with alendronate or risedronate.
Bone 2011;49(6):1160-5.
2011: Bernhard Pemmer; Roger J Phipps; Susan Reinwald; Rolf Simon; Stephan Smolek; Christina Streli; Peter Wobrauschek; Matthew R Allen; David B Burr; Keith W Condon; Robyn K Fuchs; Jochen G Hofstaetter; Klaus Klaushofer; Florian Meirer; Eleftherios P Paschalis; Paul Roschger
Increased strontium uptake in trabecular bone of ovariectomized calcium-deficient rats treated with strontium ranelate or strontium chloride.
Journal of synchrotron radiation 2011;18(Pt 6):835-41.
2011: Eleftherios P Paschalis; Richard Mendelsohn; Adele L Boskey
Infrared assessment of bone quality: a review.
Clinical orthopaedics and related research 2011;469(8):2170-8.
2010: Franz Varga; M Rumpler; R Zoehrer; C Turecek; S Spitzer; R Thaler; Eleftherios P Paschalis; Klaus Klaushofer
T3 affects expression of collagen I and collagen cross-linking in bone cell cultures.
Biochemical and biophysical research communications 2010;402(2):180-5.
2010: Barbara M Misof; Eleftherios P Paschalis; Stéphane Blouin; Nadja Fratzl-Zelman; Klaus Klaushofer; Paul Roschger
Effects of 1 year of daily teriparatide treatment on iliacal bone mineralization density distribution (BMDD) in postmenopausal osteoporotic women previously treated with alendronate or risedronate.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(11):2297-303.
2010: Sonja Gamsjaeger; A Masic; Paul Roschger; M Kazanci; J W C Dunlop; Klaus Klaushofer; Eleftherios P Paschalis; Peter Fratzl
Cortical bone composition and orientation as a function of animal and tissue age in mice by Raman spectroscopy.
Bone 2010;47(2):392-9.
2010: Chenghao Li; Oskar Paris; Stefan Siegel; Paul Roschger; Eleftherios P Paschalis; Klaus Klaushofer; Peter Fratzl
Strontium is incorporated into mineral crystals only in newly formed bone during strontium ranelate treatment.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(5):968-75.
2010: Paul Roschger; Inderchand Manjubala; Norbert Zoeger; Florian Meirer; Rolf Simon; Chenghao Li; Nadja Fratzl-Zelman; Barbara M Misof; Eleftherios P Paschalis; Christina Streli; Peter Fratzl; Klaus Klaushofer
Bone material quality in transiliac bone biopsies of postmenopausal osteoporotic women after 3 years of strontium ranelate treatment.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(4):891-900.
2010: Roman Thaler; Silvia Spitzer; Monika Rumpler; Nadja Fratzl-Zelman; Klaus Klaushofer; Eleftherios P Paschalis; Franz Varga
Differential effects of homocysteine and beta aminopropionitrile on preosteoblastic MC3T3-E1 cells.
Bone 2010;46(3):703-9.
2009: Eleftherios P Paschalis
Fourier transform infrared analysis and bone.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2009;20(6):1043-7.
2009: S Blouin; H W Thaler; C Korninger; R Schmid; J G Hofstaetter; R Zoehrer; R Phipps; Klaus Klaushofer; Paul Roschger; Eleftherios P Paschalis
Bone matrix quality and plasma homocysteine levels.
Bone 2009;44(5):959-64.
2008: Ruth Zoehrer; David W Dempster; John P Bilezikian; Hua Zhou; Shonni J Silverberg; Elizabeth Shane; Paul Roschger; Eleftherios P Paschalis; Klaus Klaushofer
Bone quality determined by Fourier transform infrared imaging analysis in mild primary hyperparathyroidism.
The Journal of clinical endocrinology and metabolism 2008;93(9):3484-9.
2008: C Turecek; Nadja Fratzl-Zelman; M Rumpler; B Buchinger; S Spitzer; R Zoehrer; E Durchschlag; Klaus Klaushofer; Eleftherios P Paschalis; Franz Varga
Collagen cross-linking influences osteoblastic differentiation.
Calcified tissue international 2008;82(5):392-400.
2008: Paul Roschger; Eleftherios P Paschalis; Peter Fratzl; Klaus Klaushofer
Bone mineralization density distribution in health and disease.
Bone 2008;42(3):456-66.
2007: M Kazanci; H D Wagner; N I Manjubala; Himadri S Gupta; Eleftherios P Paschalis; Paul Roschger; Peter Fratzl
Raman imaging of two orthogonal planes within cortical bone.
Bone 2007;41(3):456-61.
2007: Peter Fratzl; Paul Roschger; Nadja Fratzl-Zelman; Eleftherios P Paschalis; Roger Phipps; Klaus Klaushofer
Evidence that treatment with risedronate in women with postmenopausal osteoporosis affects bone mineralization and bone volume.
Calcified tissue international 2007;81(2):73-80.
2007: Paul Roschger; David W Dempster; Hua Zhou; Eleftherios P Paschalis; Shonni J Silverberg; Elizabeth Shane; John P Bilezikian; Klaus Klaushofer
New observations on bone quality in mild primary hyperparathyroidism as determined by quantitative backscattered electron imaging.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007;22(5):717-23.
2006: M Kazanci; Paul Roschger; Eleftherios P Paschalis; Klaus Klaushofer; Peter Fratzl
Bone osteonal tissues by Raman spectral mapping: orientation-composition.
Journal of structural biology 2006;156(3):489-96.
2006: M Kazanci; Peter Fratzl; Klaus Klaushofer; Eleftherios P Paschalis
Complementary information on in vitro conversion of amorphous (precursor) calcium phosphate to hydroxyapatite from Raman microspectroscopy and wide-angle X-ray scattering.
Calcified tissue international 2006;79(5):354-9.
2006: Erich Durchschlag; Eleftherios P Paschalis; Ruth Zoehrer; Paul Roschger; Peter Fratzl; Robert Recker; Roger Phipps; Klaus Klaushofer
Bone material properties in trabecular bone from human iliac crest biopsies after 3- and 5-year treatment with risedronate.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(10):1581-90.
2006: Ruth Zoehrer; Paul Roschger; Eleftherios P Paschalis; Jochen G Hofstaetter; Erich Durchschlag; Peter Fratzl; Roger Phipps; Klaus Klaushofer
Effects of 3- and 5-year treatment with risedronate on bone mineralization density distribution in triple biopsies of the iliac crest in postmenopausal women.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(7):1106-12.
2005: Adele L Boskey; Edward DiCarlo; Eleftherios P Paschalis; Paul West; Richard Mendelsohn
Comparison of mineral quality and quantity in iliac crest biopsies from high- and low-turnover osteoporosis: an FT-IR microspectroscopic investigation.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2005;16(12):2031-8.
2005: Eleftherios P Paschalis; Emmett Glass; David W Donley; Erik Fink Eriksen
Bone mineral and collagen quality in iliac crest biopsies of patients given teriparatide: new results from the fracture prevention trial.
The Journal of clinical endocrinology and metabolism 2005;90(8):4644-9.
2004: Eleftherios P Paschalis; Elizabeth Shane; George P Lyritis; Grigoris Skarantavos; Richard Mendelsohn; Adele L Boskey
Bone fragility and collagen cross-links.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(12):2000-4.
2004: Hao Ouyang; Pamela J Sherman; Eleftherios P Paschalis; Adele L Boskey; Richard Mendelsohn
Fourier transform infrared microscopic imaging: effects of estrogen and estrogen deficiency on fracture healing in rat femurs.
Applied spectroscopy 2004;58(1):1-9.
2003: Eleftherios P Paschalis; R Recker; Edward DiCarlo; Stephen B Doty; E Atti; Adele L Boskey
Distribution of collagen cross-links in normal human trabecular bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(11):1942-6.
2003: Kostas Verdelis; Miles A Crenshaw; Eleftherios P Paschalis; Stephen B Doty; E Atti; Adele L Boskey
Spectroscopic imaging of mineral maturation in bovine dentin.
Journal of dental research 2003;82(9):697-702.
2003: Eleftherios P Paschalis; Adele L Boskey; M Kassem; Erik Fink Eriksen
Effect of hormone replacement therapy on bone quality in early postmenopausal women.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(6):955-9.
2003: Yoshiyuki Mochida; Wagner R Duarte; Hideki Tanzawa; Eleftherios P Paschalis; Mitsuo Yamauchi
Decorin modulates matrix mineralization in vitro.
Biochemical and biophysical research communications 2003;305(1):6-9.
2003: Eleftherios P Paschalis; David B Burr; Richard Mendelsohn; Janet Hock; Adele L Boskey
Bone mineral and collagen quality in humeri of ovariectomized cynomolgus monkeys given rhPTH(1-34) for 18 months.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(4):769-75.
2003: Robert D Blank; Todd Baldini; Michael Kaufman; Stephanie Bailey; Rajarsi Gupta; Yevgeniy Yershov; Adele L Boskey; Susan N Coppersmith; Peter Demant; Eleftherios P Paschalis
Spectroscopically determined collagen Pyr/deH-DHLNL cross-link ratio and crystallinity indices differ markedly in recombinant congenic mice with divergent calculated bone tissue strength.
Connective tissue research 2003;44(3-4):134-42.
2002: E Atti; S Gomez; S M Wahl; Richard Mendelsohn; Eleftherios P Paschalis; Adele L Boskey
Effects of transforming growth factor-beta deficiency on bone development: a Fourier transform-infrared imaging analysis.
Bone 2002;31(6):675-84.
2002: Barbara D Boyan; Lynda F Bonewald; Eleftherios P Paschalis; Christoph H Lohmann; J Rosser; David L Cochran; David Dean; Zvi Schwartz; A L Boskey
Osteoblast-mediated mineral deposition in culture is dependent on surface microtopography.
Calcified tissue international 2002;71(6):519-29.
2002: Adele L Boskey; Lyudmila Spevak; Eleftherios P Paschalis; Stephen B Doty; Marc McKee
Osteopontin deficiency increases mineral content and mineral crystallinity in mouse bone.
Calcified tissue international 2002;71(2):145-54.
2002: S Aparicio; Stephen B Doty; Nancy Pleshko Camacho; Eleftherios P Paschalis; Lyudmila Spevak; Richard Mendelsohn; Adele L Boskey
Optimal methods for processing mineralized tissues for Fourier transform infrared microspectroscopy.
Calcified tissue international 2002;70(5):422-9.
2002: Lisa M Childs; Eleftherios P Paschalis; Lianping Xing; William C Dougall; Dirk Anderson; Adele L Boskey; J Edward Puzas; Randy N Rosier; Regis J O'Keefe; Brendan F Boyce; Edward M Schwarz
In vivo RANK signaling blockade using the receptor activator of NF-kappaB:Fc effectively prevents and ameliorates wear debris-induced osteolysis via osteoclast depletion without inhibiting osteogenesis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(2):192-9.
2002: Adele L Boskey; Eleftherios P Paschalis; Itzhak Binderman; Stephen B Doty
BMP-6 accelerates both chondrogenesis and mineral maturation in differentiating chick limb-bud mesenchymal cell cultures.
Journal of cellular biochemistry 2002;84(3):509-19.
2001: Yuan-Di C Halvorsen; D Franklin; A L Bond; Daron C Hitt; C Auchter; A L Boskey; Eleftherios P Paschalis; William O Wilkison; Jeffrey M Gimble
Extracellular matrix mineralization and osteoblast gene expression by human adipose tissue-derived stromal cells.
Tissue engineering 2001;7(6):729-41.
2001: Eleftherios P Paschalis; Kostas Verdelis; Stephen B Doty; Adele L Boskey; Richard Mendelsohn; Mitsuo Yamauchi
Spectroscopic characterization of collagen cross-links in bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(10):1821-8.
2001: L M Miller; V Vairavamurthy; M R Chance; Richard Mendelsohn; Eleftherios P Paschalis; F Betts; Adele L Boskey
In situ analysis of mineral content and crystallinity in bone using infrared micro-spectroscopy of the nu(4) PO(4)(3-) vibration.
Biochimica et biophysica acta 2001;1527(1-2):11-9.
2001: H Ou-Yang; Eleftherios P Paschalis; W E Mayo; A L Boskey; Richard Mendelsohn
Infrared microscopic imaging of bone: spatial distribution of CO3(2-).
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(5):893-900.
2001: M Khan; Mitsuo Yamauchi; S Srisawasdi; D Stiner; Stephen B Doty; Eleftherios P Paschalis; Adele L Boskey
Homocysteine decreases chondrocyte-mediated matrix mineralization in differentiating chick limb-bud mesenchymal cell micro-mass cultures.
Bone 2001;28(4):387-98.
2000: S J Gadeleta; Adele L Boskey; Eleftherios P Paschalis; C Carlson; F Menschik; Todd Baldini; M Peterson; Clare M Rimnac
A physical, chemical, and mechanical study of lumbar vertebrae from normal, ovariectomized, and nandrolone decanoate-treated cynomolgus monkeys (Macaca fascicularis).
Bone 2000;27(4):541-50.
2000: Eleftherios P Paschalis; Richard Mendelsohn
Variations in the individual thick lamellar properties within osteons by nanodentation.
Bone 2000;26(5):545-6.
2000: H Ou-Yang; Eleftherios P Paschalis; A L Boskey; Richard Mendelsohn
Two-dimensional vibrational correlation spectroscopy of in vitro hydroxyapatite maturation.
Biopolymers 2000;57(3):129-39.
1999: Marie-Claude Monier-Faugere; Zhaopo Geng; Eleftherios P Paschalis; Q Qi; I Arnala; F Bauss; A L Boskey; Hartmut H Malluche
Intermittent and continuous administration of the bisphosphonate ibandronate in ovariohysterectomized beagle dogs: effects on bone morphometry and mineral properties.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(10):1768-78.
1999: Nancy Pleshko Camacho; S Rinnerthaler; Eleftherios P Paschalis; Richard Mendelsohn; Adele L Boskey; Peter Fratzl
Complementary information on bone ultrastructure from scanning small angle X-ray scattering and Fourier-transform infrared microspectroscopy.
Bone 1999;25(3):287-93.
1998: Curtis Marcott; R C Reeder; Eleftherios P Paschalis; D N Tatakis; A L Boskey; Richard Mendelsohn
Infrared microspectroscopic imaging of biomineralized tissues using a mercury-cadmium-telluride focal-plane array detector.
Cellular and molecular biology (Noisy-le-Grand, France) 1998;44(1):109-15.
1997: Eleftherios P Paschalis; F Betts; Edward DiCarlo; Richard Mendelsohn; Adele L Boskey
FTIR microspectroscopic analysis of human iliac crest biopsies from untreated osteoporotic bone.
Calcified tissue international 1997;61(6):487-92.
1997: Eleftherios P Paschalis; F Betts; Edward DiCarlo; Richard Mendelsohn; Adele L Boskey
FTIR microspectroscopic analysis of normal human cortical and trabecular bone.
Calcified tissue international 1997;61(6):480-6.
1996: Eleftherios P Paschalis; Edward DiCarlo; F Betts; P Sherman; Richard Mendelsohn; Adele L Boskey
FTIR microspectroscopic analysis of human osteonal bone.
Calcified tissue international 1996;59(6):480-7.
1996: Eleftherios P Paschalis; O Jacenko; B Olsen; Richard Mendelsohn; Adele L Boskey
Fourier transform infrared microspectroscopic analysis identifies alterations in mineral properties in bones from mice transgenic for type X collagen.
Bone 1996;19(2):151-6.
1996: Eleftherios P Paschalis; O Jacenko; B Olsen; B deCrombrugghe; Adele L Boskey
The role of type X collagen in endochondral ossification as deduced by Fourier transform infrared microscopy analysis.
Connective tissue research 1996;35(1-4):371-7.
1996: S J Gadaleta; Eleftherios P Paschalis; F Betts; Richard Mendelsohn; Adele L Boskey
Fourier transform infrared spectroscopy of the solution-mediated conversion of amorphous calcium phosphate to hydroxyapatite: new correlations between X-ray diffraction and infrared data.
Calcified tissue international 1996;58(1):9-16.