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Virginia Pascual

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Nathalie Schmitt; Mau V Tran; Jacques Banchereau; Salah Eddine Bentebibel; Derek Blankenship; Stephanie Boisson-Dupuis; Laure Bourdery; Jacinta Bustamante; Jean-Laurent Casanova; Fran Hamlin; Virginia Pascual; Daniel A Savino; Hideki Ueno
IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans.
Junnie Yu; Virginia Pascual; Stephane Pourpe; Yuanyuan Wang; Esperanza Anguiano; Jacques Banchereau; Christian Becker; Kristina Goller; Julie Helft; Marylene Leboeuf; Florentina Marches; Miriam Merad; Karolina Palucka
Human CD1c(+) Dendritic Cells Drive the Differentiation of CD103(+) CD8(+) Mucosal Effector T Cells via the Cytokine TGF-β.
Salah-Eddine Bentebibel; Derek Blankenship; Emilio Flano; Adolfo Garcia-Sastre; Carson Harrod; Santiago Lopez; Asuncion Mejias; Cynthia Mueller; Gerlinde Obermoser; A Karolina Palucka; Virginia Pascual; Octavio Ramilo; Nathalie Schmitt; Randy A Albrecht; Jacques Banchereau; Hui Xu; Hideki Ueno
Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination.

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2013: Nathalie Schmitt; Mau V Tran; Jacques Banchereau; Salah Eddine Bentebibel; Derek Blankenship; Stephanie Boisson-Dupuis; Laure Bourdery; Jacinta Bustamante; Jean-Laurent Casanova; Fran Hamlin; Virginia Pascual; Daniel A Savino; Hideki Ueno
IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans.
Blood 2013;121(17):3375-85.
2013: Junnie Yu; Virginia Pascual; Stephane Pourpe; Yuanyuan Wang; Esperanza Anguiano; Jacques Banchereau; Christian Becker; Kristina Goller; Julie Helft; Marylene Leboeuf; Florentina Marches; Miriam Merad; Karolina Palucka
Human CD1c(+) Dendritic Cells Drive the Differentiation of CD103(+) CD8(+) Mucosal Effector T Cells via the Cytokine TGF-β.
Immunity 2013;38(4):818-30.
2013: Salah-Eddine Bentebibel; Derek Blankenship; Emilio Flano; Adolfo Garcia-Sastre; Carson Harrod; Santiago Lopez; Asuncion Mejias; Cynthia Mueller; Gerlinde Obermoser; A Karolina Palucka; Virginia Pascual; Octavio Ramilo; Nathalie Schmitt; Randy A Albrecht; Jacques Banchereau; Hui Xu; Hideki Ueno
Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination.
Science translational medicine 2013;5(176):176ra32.
2012: Simone Caielli; Jacques Banchereau; Virginia Pascual
Neutrophils come of age in chronic inflammation.
Current opinion in immunology 2012;24(6):671-7.
2012: Jacques Banchereau; Virginia Pascual; Anne O'Garra
From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines.
Nature immunology 2012;13(10):925-31.
2012: Wei Xu; Robert Balderas; Derek Blankenship; Jean-Laurent Casanova; Sandra Clayton; Maria Teresa De La Morena; Melissa Dullaers; Marie-Cecile Herve; HyeMee Joo; SangKon Oh; Virginia Pascual; Capucine Picard; Jacques Banchereau
Macrophages induce differentiation of plasma cells through CXCL10/IP-10.
The Journal of experimental medicine 2012;209(10):1813-23, S1-2.
2012: Hyemee Joo; Jacques Banchereau; Christine Coquery; Stacey R Dillon; Ingrid Gayet; Virginia Pascual; Marilynn Punaro; Yaming Xue; Gerard Zurawski; SangKon Oh
Serum from patients with SLE instructs monocytes to promote IgG and IgA plasmablast differentiation.
The Journal of experimental medicine 2012;209(7):1335-48.
2012: Virginia Pascual; Jacques Banchereau
Tracking interferon in autoimmunity.
Immunity 2012;36(1):7-9.
2012: Chloe I Bloom; Damien Chaussabel; Christine Marian Graham; Marc Lipman; Tolu Oni; Virginia Pascual; Jose Rossello-Urgell; Fotini Rozakeas; Katalin A Wilkinson; Robert J Wilkinson; Zhaohui Xu; Jacques Banchereau; Matthew P R Berry; Anne O'Garra
Detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy.
PloS one 2012;7(10):e46191.
2012: Romain Banchereau; Derek Blankenship; Damien Chaussabel; Clarence B Creech; Alejandro Jordan-Villegas; Asuncion Mejias; Phuong Nguyen; Virginia Pascual; Monica Ardura; Nicole Baldwin; Jacques Banchereau; Jose Rossello-Urgell; Elizabeth Saye; Hui Xu; Octavio Ramilo
Host immune transcriptional profiles reflect the variability in clinical disease manifestations in patients with Staphylococcus aureus infections.
PloS one 2012;7(4):e34390.
2011: Pierre Quartier; Florence Allantaz; Rolando Cimaz; Pascal Pillet; Claude Messiaen; Christophe Bardin; Xavier Bossuyt; Anne Boutten; Jacques Bienvenu; Agnes Duquesne; Olivier Richer; Damien Chaussabel; Agnes Mogenet; Jacques Banchereau; Jean-Marc Treluyer; Paul Landais; Virginia Pascual
A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial).
Annals of the rheumatic diseases 2011;70(5):747-54.
2011: Gina S Garcia-Romo; Simone Caielli; Barbara Vega; John Connolly; Florence Allantaz; Zhaohui Xu; Marilynn Punaro; Jeanine Baisch; Cristiana Guiducci; Robert L Coffman; Franck J Barrat; Jacques Banchereau; Virginia Pascual
Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus.
Science translational medicine 2011;3(73):73ra20.
2011: Alexis Mathian; Mike Gallegos; Virginia Pascual; Jacques Banchereau; Sophie KOUTOUZOV
Interferon-α induces unabated production of short-lived plasma cells in pre-autoimmune lupus-prone (NZB×NZW)F1 mice but not in BALB/c mice.
European journal of immunology 2011;41(3):863-72.
2011: Rimpei Morita; Nathalie Schmitt; Salah-Eddine Bentebibel; Rajaram Ranganathan; Laure Bourdery; Gerard Zurawski; Emile Foucat; Melissa Dullaers; SangKon Oh; Natalie Sabzghabaei; Elizabeth M Lavecchio; Marilynn Punaro; Virginia Pascual; Jacques Banchereau; Hideki Ueno
Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion.
Immunity 2011;34(1):108-21.
2010: Elisabeth J Smith; Florence Allantaz; Lynda Bennett; Dongping Zhang; Xiaochong Gao; Geryl Wood; Daniel L Kastner; Marilynn Punaro; Ivona Aksentijevich; Virginia Pascual; Carol A Wise
Clinical, Molecular, and Genetic Characteristics of PAPA Syndrome: A Review.
Current genomics 2010;11(7):519-27.
2010: Matthew P R Berry; Christine Marian Graham; Finlay W McNab; Zhaohui Xu; Susannah A A Bloch; Tolu Oni; Katalin A Wilkinson; Romain Banchereau; Jason Skinner; Robert J Wilkinson; Charles Quinn; Derek Blankenship; Ranju Dhawan; John J Cush; Asuncion Mejias; Octavio Ramilo; Onn M Kon; Virginia Pascual; Jacques Banchereau; Damien Chaussabel; Anne O'Garra
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis.
Nature 2010;466(7309):973-7.
2010: G Obermoser; Virginia Pascual
The interferon-alpha signature of systemic lupus erythematosus.
Lupus 2010;19(9):1012-9.
2010: Cristiana Guiducci; Mei Gong; Zhaohui Xu; Michelle Gill; Damien Chaussabel; Thea Meeker; Jean H Chan; Tracey Wright; Marilynn Punaro; Silvia Bolland; Vassili Soumelis; Jacques Banchereau; Robert L Coffman; Virginia Pascual; Franck J Barrat
TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus.
Nature 2010;465(7300):937-41.
2010: Hideki Ueno; Nathalie Schmitt; Eynav Klechevsky; Alexander Pedroza-Gonzalez; Toshimichi Matsui; Gerard Zurawski; SangKon Oh; Joseph Fay; Virginia Pascual; Jacques Banchereau; Karolina Palucka
Harnessing human dendritic cell subsets for medicine.
Immunological reviews 2010;234(1):199-212.
2010: Damien Chaussabel; Virginia Pascual; Jacques Banchereau
Assessing the human immune system through blood transcriptomics.
BMC biology 2010;8():84.
2010: Virginia Pascual; Damien Chaussabel; Jacques Banchereau
A genomic approach to human autoimmune diseases.
Annual review of immunology 2010;28():535-71.
2009: Monica I Ardura; Romain Banchereau; Asuncion Mejias; Tiziana Di Pucchio; Casey Glaser; Florence Allantaz; Virginia Pascual; Jacques Banchereau; Damien Chaussabel; Octavio Ramilo
Enhanced monocyte response and decreased central memory T cells in children with invasive Staphylococcus aureus infections.
PloS one 2009;4(5):e5446.
2008: Damien Chaussabel; Charlie Quinn; Jing Shen; Pinakeen Patel; Casey Glaser; Nicole Baldwin; Dorothee Stichweh; Derek Blankenship; Lei Li; Indira Munagala; Lynda Bennett; Florence Allantaz; Asuncion Mejias; Monica Ardura; Ellen Kaizer; Laurence Monnet; Windy Allman; Henry Randall; Diane Johnson; Aimee Lanier; Marilynn Punaro; Knut M Wittkowski; Perrin White; Joseph Fay; Goran Klintmalm; Octavio Ramilo; A Karolina Palucka; Jacques Banchereau; Virginia Pascual
A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus.
Immunity 2008;29(1):150-64.
2008: Brun Mietzner; Makoto Tsuiji; Johannes Scheid; Klara Velinzon; Thomas Tiller; Klaus Abraham; Jose B Gonzalez; Virginia Pascual; Dorothee Stichweh; Hedda Wardemann; Michel C Nussenzweig
Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(28):9727-32.
2008: Virginia Pascual; Florence Allantaz; Pinakeen Patel; A Karolina Palucka; Damien Chaussabel; Jacques Banchereau
How the study of children with rheumatic diseases identified interferon-alpha and interleukin-1 as novel therapeutic targets.
Immunological reviews 2008;223():39-59.
2007: Florence Allantaz; Damien Chaussabel; Jacques Banchereau; Virginia Pascual
Microarray-based identification of novel biomarkers in IL-1-mediated diseases.
Current opinion in immunology 2007;19(6):623-32.
2007: Hideki Ueno; Eynav Klechevsky; Rimpei Morita; Caroline Aspord; Tinghua Cao; Toshimichi Matsui; Tiziana Di Pucchio; John Connolly; Joseph W Fay; Virginia Pascual; A Karolina Palucka; Jacques Banchereau
Dendritic cell subsets in health and disease.
Immunological reviews 2007;219():118-42.
2007: Florence Allantaz; Damien Chaussabel; Dorothee Stichweh; Lynda Bennett; Windy Allman; Asuncion Mejias; Monica Ardura; Wendy Chung; Elisabeth Smith; Carol A Wise; Karolina Palucka; Octavio Ramilo; Marilynn Punaro; Jacques Banchereau; Virginia Pascual
Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade.
The Journal of experimental medicine 2007;204(9):2131-44.
2007: Ellen C Kaizer; Casey L Glaser; Damien Chaussabel; Jacques Banchereau; Virginia Pascual; Perrin C White
Gene expression in peripheral blood mononuclear cells from children with diabetes.
The Journal of clinical endocrinology and metabolism 2007;92(9):3705-11.
2006: Virginia Pascual; Lorant Farkas; Jacques Banchereau
Systemic lupus erythematosus: all roads lead to type I interferons.
Current opinion in immunology 2006;18(6):676-82.
2005: Damien Chaussabel; Windy Allman; Asuncion Mejias; Wendy Chung; Lynda Bennett; Octavio Ramilo; Virginia Pascual; A Karolina Palucka; Jacques Banchereau
Analysis of significance patterns identifies ubiquitous and disease-specific gene-expression signatures in patient peripheral blood leukocytes.
Annals of the New York Academy of Sciences 2005;1062():146-54.
2005: Dorothee Stichweh; Virginia Pascual
Autoimmune mechanisms in children with systemic lupus erythematosus.
Current rheumatology reports 2005;7(6):421-6.
2005: Dorothee Stichweh; Virginia Pascual
[Systemic lupus erythematosus in children].
Anales de pediatría (Barcelona, Spain : 2003) 2005;63(4):321-9.
2005: Virginia Pascual; Florence Allantaz; Edsel Arce; Marilynn Punaro; Jacques Banchereau
Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade.
The Journal of experimental medicine 2005;201(9):1479-86.
2005: Dorothee Stichweh; Marilynn Punaro; Virginia Pascual
Dramatic improvement of pyoderma gangrenosum with infliximab in a patient with PAPA syndrome.
Pediatric dermatology 2005;22(3):262-5.
2005: A Karolina Palucka; Jean-Philippe Blanck; Lynda Bennett; Virginia Pascual; Jacques Banchereau
Cross-regulation of TNF and IFN-alpha in autoimmune diseases.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3372-7.
2005: A Karolina Palucka; Beatrice Laupeze; Caroline Aspord; Hiroaki Saito; Gaetan Jego; Joseph Fay; Sophie Paczesny; Virginia Pascual; Jacques Banchereau
Immunotherapy via dendritic cells.
Advances in experimental medicine and biology 2005;560():105-14.
2005: Gaetan Jego; Virginia Pascual; A Karolina Palucka; Jacques Banchereau
Dendritic cells control B cell growth and differentiation.
Current directions in autoimmunity 2005;8():124-39.
2004: Dorothee Stichweh; Edsel Arce; Virginia Pascual
Update on pediatric systemic lupus erythematosus.
Current opinion in rheumatology 2004;16(5):577-87.
2004: Jacques Banchereau; Virginia Pascual; A Karolina Palucka
Autoimmunity through cytokine-induced dendritic cell activation.
Immunity 2004;20(5):539-50.
2004: Nai-Ying Zheng; Kenneth Wilson; Xiaojian Wang; Angela Boston; Grant R Kolar; Stephen M Jackson; Yong-Jun Liu; Virginia Pascual; J Donald Capra; Patrick C Wilson
Human immunoglobulin selection associated with class switch and possible tolerogenic origins for C delta class-switched B cells.
The Journal of clinical investigation 2004;113(8):1188-201.
2003: Virginia Pascual; Jacques Banchereau; A Karolina Palucka
The central role of dendritic cells and interferon-alpha in SLE.
Current opinion in rheumatology 2003;15(5):548-56.
2003: Gaetan Jego; A Karolina Palucka; Jean-Philippe Blanck; Cécile Chalouni; Virginia Pascual; Jacques Banchereau
Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6.
Immunity 2003;19(2):225-34.
2003: Jacques Banchereau; Sophie Paczesny; Patrick Blanco; Lynda Bennett; Virginia Pascual; Joseph Fay; A Karolina Palucka
Dendritic cells: controllers of the immune system and a new promise for immunotherapy.
Annals of the New York Academy of Sciences 2003;987():180-7.
2003: Cécile Chalouni; Jacques Banchereau; Anne B Vogt; Virginia Pascual; Jean Davoust
Human germinal center B cells differ from naive and memory B cells by their aggregated MHC class II-rich compartments lacking HLA-DO.
International immunology 2003;15(4):457-66.
2003: Lynda Bennett; A Karolina Palucka; Edsel Arce; Victoria Cantrell; Josef Borvak; Jacques Banchereau; Virginia Pascual
Interferon and granulopoiesis signatures in systemic lupus erythematosus blood.
The Journal of experimental medicine 2003;197(6):711-23.
2003: Jacques Banchereau; Joseph Fay; Virginia Pascual; A Karolina Palucka
Dendritic cells: controllers of the immune system and a new promise for immunotherapy.
Novartis Foundation symposium 2003;252():226-35; discussion 235-8, 257-67.
2002: Michelle A Gill; Patrick Blanco; Edsel Arce; Virginia Pascual; Jacques Banchereau; A Karolina Palucka
Blood dendritic cells and DC-poietins in systemic lupus erythematosus.
Human immunology 2002;63(12):1172-80.
2002: A Karolina Palucka; Jacques Banchereau; Patrick Blanco; Virginia Pascual
The interplay of dendritic cell subsets in systemic lupus erythematosus.
Immunology and cell biology 2002;80(5):484-8.
2002: Ana I Quintero-Del-Rio; Marilynn Punaro; Virginia Pascual
Faces of eosinophilic fasciitis in childhood.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2002;8(2):99-103.
2001: P Blanco; A Karolina Palucka; M Gill; Virginia Pascual; Jacques Banchereau
Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.
Science (New York, N.Y.) 2001;294(5546):1540-3.
2001: Edsel Arce; D G Jackson; Michelle A Gill; LB Bennett; Jacques Banchereau; Virginia Pascual
Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):2361-9.
2000: JK Frazer; D G Jackson; Philippe Gaillard; M Lutter; Yong-Jun Liu; Jacques Banchereau; J Donald Capra; Virginia Pascual
Identification of centerin: a novel human germinal center B cell-restricted serpin.
European journal of immunology 2000;30(10):3039-48.
2000: Carol A Wise; LB Bennett; Virginia Pascual; Joseph D Gillum; Anne M Bowcock
Localization of a gene for familial recurrent arthritis.
Arthritis and rheumatism 2000;43(9):2041-5.
2000: Patrick C Wilson; Kenneth Wilson; Yong-Jun Liu; Jacques Banchereau; Virginia Pascual; J Donald Capra
Receptor revision of immunoglobulin heavy chain variable region genes in normal human B lymphocytes.
The Journal of experimental medicine 2000;191(11):1881-94.
1998: Theodore J Yun; Preet M Chaudhary; Geraldine L Shu; JK Frazer; MK Ewings; Stephen M Schwartz; Virginia Pascual; Leroy Hood; Edward A Clark
OPG/FDCR-1, a TNF receptor family member, is expressed in lymphoid cells and is up-regulated by ligating CD40.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(11):6113-21.
1998: Pila Estess; HC DeGrendele; Virginia Pascual; Mark Siegelman
Functional activation of lymphocyte CD44 in peripheral blood is a marker of autoimmune disease activity.
The Journal of clinical investigation 1998;102(6):1173-82.
1998: P Wilson; Yong-Jun Liu; Jacques Banchereau; J Donald Capra; Virginia Pascual
Amino acid insertions and deletions contribute to diversify the human Ig repertoire.
Immunological reviews 1998;162():143-51.
1998: Patrick C Wilson; O de Bouteiller; Yong-Jun Liu; KN Potter; Jacques Banchereau; J Donald Capra; Virginia Pascual
Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes.
The Journal of experimental medicine 1998;187(1):59-70.
1997: Virginia Pascual; Y J Liu; Jacques Banchereau
Normal human B cell sub-populations and their malignant counterparts.
Baillière's clinical haematology 1997;10(3):525-38.
1997: JK Frazer; Virginia Pascual; J Donald Capra
RDA of lymphocyte subsets.
Journal of immunological methods 1997;207(1):1-12.
1997: JK Frazer; J LeGros; O de Bouteiller; Yong-Jun Liu; Jacques Banchereau; Virginia Pascual; J Donald Capra
Identification and cloning of genes expressed by human tonsillar B lymphocyte subsets.
Annals of the New York Academy of Sciences 1997;815():316-8.
1997: Virginia Pascual; P Wilson; Yong-Jun Liu; Jacques Banchereau; J Donald Capra
Biased VH4 gene segment repertoire in the human tonsil.
Chemical immunology 1997;67():45-57.
1997: KN Potter; Y Li; Virginia Pascual; J Donald Capra
Staphylococcal protein A binding to VH3 encoded immunoglobulins.
International reviews of immunology 1997;14(4):291-308.
1995: J S Andris; S R Abraham; Virginia Pascual; Maria Pia Pistillo; Stefano Mantero; Giovanni Battista Ferrara; J Donald Capra
The human antibody repertoire: heavy and light chain variable region gene usage in six alloantibodies specific for human HLA class I and class II alloantigens.
Molecular immunology 1995;32(14-15):1105-22.
1995: G F Widhopf; Virginia Pascual; R Baer; J Donald Capra
Characterization and genomic mapping of a novel leader peptide associated with the human VH4-21 (VH4-34) gene segment.
Annals of the New York Academy of Sciences 1995;764():62-71.
1994: S V Kristiansen; Virginia Pascual; P E Lipsky
Staphylococcal protein A induces biased production of Ig by VH3-expressing B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(7):2974-82.
1994: Virginia Pascual; Yong-Jun Liu; A Magalski; O de Bouteiller; Jacques Banchereau; J Donald Capra
Analysis of somatic mutation in five B cell subsets of human tonsil.
The Journal of experimental medicine 1994;180(1):329-39.
1994: Virginia Pascual; S Cha; M Eric Gershwin; J Donald Capra; Patrick S C Leung
Nucleotide sequence analysis of natural and combinatorial anti-PDC-E2 antibodies in patients with primary biliary cirrhosis. Recapitulating immune selection with molecular biology.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(5):2577-85.
1993: Virginia Pascual; Linda A Verkruyse; M L Casey; J Donald Capra
Analysis of Ig H chain gene segment utilization in human fetal liver. Revisiting the "proximal utilization hypothesis".
Journal of immunology (Baltimore, Md. : 1950) 1993;151(8):4164-72.
1993: I Randen; KN Potter; Y Li; Keith M Thompson; Virginia Pascual; Oystein T Førre; Jacob B Natvig; J Donald Capra
Complementarity-determining region 2 is implicated in the binding of staphylococcal protein A to human immunoglobulin VHIII variable regions.
European journal of immunology 1993;23(10):2682-6.
1993: KN Potter; Y Li; Virginia Pascual; R C Williams; L C Byres; MB Spellerberg; F K Stevenson; J Donald Capra
Molecular characterization of a cross-reactive idiotope on human immunoglobulins utilizing the VH4-21 gene segment.
The Journal of experimental medicine 1993;178(4):1419-28.
1993: I Randen; Virginia Pascual; K Victor; Keith M Thompson; Oystein T Førre; J Donald Capra; Jacob B Natvig
Synovial IgG rheumatoid factors show evidence of an antigen-driven immune response and a shift in the V gene repertoire compared to IgM rheumatoid factors.
European journal of immunology 1993;23(6):1220-5.
1993: K D Victor; Virginia Pascual; A E Stitzel; George C Tsokos; J Donald Capra; R E Spitzer
Nucleotide sequence of a human autoantibody to the alternative pathway C3/C5 convertase (C3NeF).
Hybridoma 1993;12(3):231-7.
1992: K D Victor; Virginia Pascual; A K Lefvert; J Donald Capra
Human anti-acetylcholine receptor antibodies use variable gene segments analogous to those used in autoantibodies of various specificities.
Molecular immunology 1992;29(12):1501-6.
1992: Virginia Pascual; K Victor; MB Spellerberg; T J Hamblin; F K Stevenson; J Donald Capra
VH restriction among human cold agglutinins. The VH4-21 gene segment is required to encode anti-I and anti-i specificities.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(7):2337-44.
1992: K D Victor; Virginia Pascual; C L Williams; V A Lennon; J Donald Capra
Human monoclonal striational autoantibodies isolated from thymic B lymphocytes of patients with myasthenia gravis use VH and VL gene segments associated with the autoimmune repertoire.
European journal of immunology 1992;22(9):2231-6.
1992: Virginia Pascual; K Victor; I Randen; K Thompson; M Steinitz; Oystein T Førre; S M Fu; Jacob B Natvig; J Donald Capra
Nucleotide sequence analysis of rheumatoid factors and polyreactive antibodies derived from patients with rheumatoid arthritis reveals diverse use of VH and VL gene segments and extensive variability in CDR-3.
Scandinavian journal of immunology 1992;36(2):349-62.
1992: I Randen; Keith M Thompson; Virginia Pascual; K Victor; D Beale; J Coadwell; Oystein T Førre; J Donald Capra; Jacob B Natvig
Rheumatoid factor V genes from patients with rheumatoid arthritis are diverse and show evidence of an antigen-driven response.
Immunological reviews 1992;128():49-71.
1992: I Randen; D Brown; Keith M Thompson; N Hughes-Jones; Virginia Pascual; K Victor; J Donald Capra; Oystein T Førre; Jacob B Natvig
Clonally related IgM rheumatoid factors undergo affinity maturation in the rheumatoid synovial tissue.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(10):3296-301.
1992: P J Kelly; Virginia Pascual; J Donald Capra; P E Lipsky
Anti-CD3-stimulated T cells induce the production of multiple Ig H chain isotypes by individual human peripheral B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(5):1294-301.
1992: Virginia Pascual; J Donald Capra
VH4-21, a human VH gene segment overrepresented in the autoimmune repertoire.
Arthritis and rheumatism 1992;35(1):11-8.
1992: Virginia Pascual; K Victor; I Randen; K Thompson; Jacob B Natvig; J Donald Capra
IgM rheumatoid factors in patients with rheumatoid arthritis derive from a diverse array of germline immunoglobulin genes and display little evidence of somatic variation.
The Journal of rheumatology. Supplement 1992;32():50-3.
1992: Virginia Pascual; G Widhopf; J Donald Capra
The human VH repertoire: a restricted set of VH genes may be the target of immune regulation.
International reviews of immunology 1992;8(2-3):147-57.
1991: Virginia Pascual; J Donald Capra
B-cell superantigens?
Current biology : CB 1991;1(5):315-7.
1991: Keith M Thompson; J Sutherland; G Barden; M D Melamed; I Randen; Jacob B Natvig; Virginia Pascual; J D Capra; F K Stevenson
Human monoclonal antibodies against blood group antigens preferentially express a VH4-21 variable region gene-associated epitope.
Scandinavian journal of immunology 1991;34(4):509-18.
1991: Virginia Pascual; K Victor; D Lelsz; MB Spellerberg; T J Hamblin; Keith M Thompson; I Randen; Jacob B Natvig; J Donald Capra; F K Stevenson
Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(12):4385-91.
1991: K Victor; J Andris; Virginia Pascual; J Donald Capra
Some cautionary notes on interpreting immunoglobulin variable gene segment restriction in autoimmune disease.
Immunology series 1991;54():1-12.
1991: Virginia Pascual; J Donald Capra
Human immunoglobulin heavy-chain variable region genes: organization, polymorphism, and expression.
Advances in immunology 1991;49():1-74.
1990: Virginia Pascual; I Randen; K Thompson; Mouldy Sioud; O Forre; Jacob B Natvig; J Donald Capra
The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidence that some autoantibodies are unmutated copies of germ line genes.
The Journal of clinical investigation 1990;86(4):1320-8.
1990: Jacob B Natvig; I Randen; K Thompson; Oystein T Førre; R A Mageed; R Jefferis; D A Carson; H Tighe; Virginia Pascual; K D Victor
Probing of the rheumatoid factor (RF) V gene repertoire in rheumatoid arthritis (RA) by hybridoma clones.
Clinical and experimental rheumatology 1990;8 Suppl 5():75-80.
1990: R W van der Heijden; H Bunschoten; Virginia Pascual; F G Uytdehaag; D M Osterhaus; J Donald Capra
Nucleotide sequence of a human monoclonal anti-idiotypic antibody specific for a rabies virus-neutralizing monoclonal idiotypic antibody reveals extensive somatic variability suggestive of an antigen-driven immune response.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(7):2835-9.
1990: Virginia Pascual; J Andris; J Donald Capra
Heavy chain variable region gene utilization in human antibodies.
International reviews of immunology 1990;5(3-4):231-8.