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Jean-Max Pasquet

Research Profile

Anatomy

Physiology

Disorders

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Chemicals & Drugs

Procedures

Flow Cytometry

Phenomena

Co-author Network

Publications

TOP 3
Alexandre Puissant; Sophie Raynaud; Guillaume ROBERT; Mélanie Tichet; Issam Ben Sahra; Jill-Patrice Cassuto; Yann Chéli; Thomas Cluzeau; Marcel Deckert; Maeva Dufies; Nina Fenouille; Arnaud Jacquel; Laurence Legros; Frederic Luciano; François-Xavier Mahon; Jean-Max Pasquet; Patrick Auberger
Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness.
Claire Drullion; Romain Gioia; Valérie Lagarde; Patrick Legembre; Eric Lippert; François-Xavier Mahon; Bruno Cardinaud; Muriel Priault; Jean-Max Pasquet
Mycophenolic Acid overcomes imatinib and nilotinib resistance of chronic myeloid leukemia cells by apoptosis or a senescent-like cell cycle arrest.
C Drullion; R Gioia; Valérie Lagarde; François-Xavier Mahon; P Auberger; A Brisson; Mojgan Djavaheri-Mergny; Muriel Priault; S Tan; C Trégoat; Jean-Max Pasquet
Apoptosis and autophagy have opposite roles on imatinib-induced K562 leukemia cell senescence.

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All Publications

2012: Alexandre Puissant; Sophie Raynaud; Guillaume ROBERT; Mélanie Tichet; Issam Ben Sahra; Jill-Patrice Cassuto; Yann Chéli; Thomas Cluzeau; Marcel Deckert; Maeva Dufies; Nina Fenouille; Arnaud Jacquel; Laurence Legros; Frederic Luciano; François-Xavier Mahon; Jean-Max Pasquet; Patrick Auberger
Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness.
Journal of molecular cell biology 2012;4(4):207-20.
2012: Claire Drullion; Romain Gioia; Valérie Lagarde; Patrick Legembre; Eric Lippert; François-Xavier Mahon; Bruno Cardinaud; Muriel Priault; Jean-Max Pasquet
Mycophenolic Acid overcomes imatinib and nilotinib resistance of chronic myeloid leukemia cells by apoptosis or a senescent-like cell cycle arrest.
Leukemia research and treatment 2012;2012():861301.
2012: C Drullion; R Gioia; Valérie Lagarde; François-Xavier Mahon; P Auberger; A Brisson; Mojgan Djavaheri-Mergny; Muriel Priault; S Tan; C Trégoat; Jean-Max Pasquet
Apoptosis and autophagy have opposite roles on imatinib-induced K562 leukemia cell senescence.
Cell death & disease 2012;3():e373.
2011: Romain Gioia; Valérie Lagarde; Cédric Leroy; Eric Lippert; François-Xavier Mahon; Claire Drullion; Stéphanie Dulucq; Gabriel Etienne; Serge Roche; Jean-Max Pasquet
Quantitative phosphoproteomics revealed interplay between Syk and Lyn in the resistance to nilotinib in chronic myeloid leukemia cells.
Blood 2011;118(8):2211-21.
2011: Gabriel Etienne; Bertrand Garbay; Valérie Lagarde; François-Xavier Mahon; Jean-Max Pasquet; Josy Reiffers; Claudine Chollet; Patricia Costaglioli; Maryse Dupouy; Béatrice Turcq
α-defensin 1-3 and α-defensin 4 as predictive markers of imatinib resistance and relapse in CML patients.
Disease markers 2011;30(5):221-7.
2010: Nina Fenouille; Alexandre Puissant; Maeva Dufies; Guillaume Robert; Arnaud Jacquel; Mickael Ohanna; Marcel Deckert; Jean-Max Pasquet; François-Xavier Mahon; Jill-Patrice Cassuto; Sophie Raynaud; Sophie Tartare-Deckert; Patrick Auberger
Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.
Cancer research 2010;70(23):9659-70.
2009: Gwendaline Guidicelli; Benjamin Chaigne-Delalande; Marie-Sarah Dilhuydy; Benoît Pinson; Walid Mahfouf; Jean-Max Pasquet; François-Xavier Mahon; Philippe Pourquier; Jean-François Moreau; Patrick Legembre
The necrotic signal induced by mycophenolic acid overcomes apoptosis-resistance in tumor cells.
PloS one 2009;4(5):e5493.
2008: François-Xavier Mahon; Sandrine Hayette; Valérie Lagarde; Francis Belloc; Béatrice Turcq; Franck E Nicolini; Coralie Belanger; Paul W Manley; Cédric Leroy; Gabriel Etienne; Serge Roche; Jean-Max Pasquet
Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, or Src kinase overexpression.
Cancer research 2008;68(23):9809-16.
2008: Chloé James; Frederic Mazurier; Sabrina Dupont; Ronan Chaligne; Isabelle Lamrissi-Garcia; Micheline Tulliez; Eric Lippert; François-Xavier Mahon; Jean-Max Pasquet; Gabriel Etienne; François Delhommeau; Stephane Giraudier; William Vainchenker; Hubert de Verneuil
The hematopoietic stem cell compartment of JAK2V617F-positive myeloproliferative disorders is a reflection of disease heterogeneity.
Blood 2008;112(6):2429-38.
2008: Marion Pocaly; Valérie Lagarde; Gabriel Etienne; Maryse Dupouy; Delphine Lapaillerie; Stéphane Claverol; Sébastien Vilain; Marc Bonneu; Béatrice Turcq; François-Xavier Mahon; Jean-Max Pasquet
Proteomic analysis of an imatinib-resistant K562 cell line highlights opposing roles of heat shock cognate 70 and heat shock 70 proteins in resistance.
Proteomics 2008;8(12):2394-406.
2008: A Soria; Muriel Cario-André; Sébastien Lepreux; Hamid Rezavani; Jean-Max Pasquet; Catherine Pain; Thierry Schaeverbeke; François-Xavier Mahon; Alain Taïeb
The effect of imatinib (Glivec) on scleroderma and normal dermal fibroblasts: a preclinical study.
Dermatology (Basel, Switzerland) 2008;216(2):109-17.
2007: M Pocaly; Valérie Lagarde; Gabriel Etienne; J-A Ribeil; Stéphane Claverol; Marc Bonneu; François Moreau-Gaudry; V Guyonnet-Duperat; O Hermine; Junia V Melo; Maryse Dupouy; B Turcq; François-Xavier Mahon; Jean-Max Pasquet
Overexpression of the heat-shock protein 70 is associated to imatinib resistance in chronic myeloid leukemia.
Leukemia 2007;21(1):93-101.
2005: Yahsou Delmas; Jean-François Viallard; Anne Solanilla; julien villeneuve; Jean-Max Pasquet; Francis Belloc; Isabelle Dubus; Julie Déchanet-Merville; Pierre Merville; Patrick Blanco; Jean-Luc Pellegrin; Alan T Nurden; Christian Combe; Jean Ripoche
Activation of mesangial cells by platelets in systemic lupus erythematosus via a CD154-dependent induction of CD40.
Kidney international 2005;68(5):2068-78.
2005: Yahsou Delmas; Jean-François Viallard; julien villeneuve; Christophe Grosset; Jean-Max Pasquet; Julie Déchanet-Merville; Paquita Nurden; Jean-Luc Pellegrin; Jean Rosenbaum; Christian Combe; Alan T Nurden; Jean Ripoche
[Platelet-associated CD154: a new interface in haemostasis and in the inflammatory reaction].
Médecine sciences : M/S 2005;21(10):825-31.
2005: Yue Han; Jean-Max Pasquet; Alan Nurden; Zhao-yue Wang; Chang-Geng Ruan
[Functions of thrombin receptors in the reversible distribution of platelet surface glycoprotein I balpha in activated platelets].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 2005;26(3):152-6.
2005: Anne Solanilla; Jean-Max Pasquet; Jean-François Viallard; Cécile Contin; Christophe Grosset; Julie Déchanet-Merville; Maryse Dupouy; Marc Landry; Francis Belloc; Paquita Nurden; Patrick Blanco; Jean-François Moreau; Jean-Luc Pellegrin; Alan T Nurden; Jean Ripoche
Platelet-associated CD154 in immune thrombocytopenic purpura.
Blood 2005;105(1):215-8.
2004: Vanessa Desplat; Valérie Lagarde; Francis Belloc; Claudine Chollet; Thibaut Leguay; Jean-Max Pasquet; Vincent Praloran; François-Xavier Mahon
Rapid detection of phosphotyrosine proteins by flow cytometric analysis in Bcr-Abl-positive cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2004;62(1):35-45.
2004: Paquita Nurden; Martine Jandrot-Perrus; Robert Combrié; Joelle Winckler; Véronique Arocas; Christelle Lecut; Jean-Max Pasquet; Thomas J Kunicki; Alan T Nurden
Severe deficiency of glycoprotein VI in a patient with gray platelet syndrome.
Blood 2004;104(1):107-14.
2003: Yue Han; Jean-Max Pasquet; Alan Nurden; Chang-Geng Ruan
[Mechanism of action of protease-activated receptors 1 and 4 in platelet activation].
Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology 2003;11(5):495-8.
2003: Y Han; Alan Nurden; Robert Combrié; Jean-Max Pasquet
Redistribution of glycoprotein Ib within platelets in response to protease-activated receptors 1 and 4: roles of cytoskeleton and calcium.
Journal of thrombosis and haemostasis : JTH 2003;1(10):2206-15.
2003: Catherine Strassel; Jean-Max Pasquet; Marie-Christine Alessi; Irène Juhan-Vague; Hervé Chambost; Robert Combrié; Paquita Nurden; Marie-Jeanne Bas; Corinne De La Salle; Jean-Pierre Cazenave; François Lanza; Alan T Nurden
A novel missense mutation shows that GPIbbeta has a dual role in controlling the processing and stability of the platelet GPIb-IX adhesion receptor.
Biochemistry 2003;42(15):4452-62.
2002: Jean-Max Pasquet; Malia Noury; Alan T Nurden
Evidence that the platelet integrin alphaIIb beta3 is regulated by the integrin-linked kinase, ILK, in a PI3-kinase dependent pathway.
Thrombosis and haemostasis 2002;88(1):115-22.
2002: Alan T Nurden; Jian Ruan; Jean-Max Pasquet; Bruno Gauthier; Robert Combrié; Thomas J Kunicki; Paquita Nurden
A novel 196Leu to Pro substitution in the beta3 subunit of the alphaIIbbeta3 integrin in a patient with a variant form of Glanzmann thrombasthenia.
Platelets 2002;13(2):101-11.
1998: Jean-Max Pasquet; J Dachary-Prigent; Alan T Nurden
Microvesicle release is associated with extensive protein tyrosine dephosphorylation in platelets stimulated by A23187 or a mixture of thrombin and collagen.
The Biochemical journal 1998;333 ( Pt 3)():591-9.
1997: J Dachary-Prigent; Jean-Max Pasquet; E Fressinaud; Florian Toti; Jean-Marie Freyssinet; Alan T Nurden
Aminophospholipid exposure, microvesiculation and abnormal protein tyrosine phosphorylation in the platelets of a patient with Scott syndrome: a study using physiologic agonists and local anaesthetics.
British journal of haematology 1997;99(4):959-67.
1997: Jean-Max Pasquet; J Dachary-Prigent; Alan T Nurden
Comparison between the loss of platelet membrane asymmetry, microvesiculation and the tyrosine phosphorylation of proteins.
Prostaglandins, leukotrienes, and essential fatty acids 1997;57(4-5):451-3.
1997: J Dachary-Prigent; Jean-Max Pasquet; Alan T Nurden
Simultaneous detection of changes in cytoplasmic Ca(2+), aminophospholipid exposure and micro-vesiculation in activated platelets.
Platelets 1997;8(6):405-12.
1996: Jean-Max Pasquet; J Dachary-Prigent; A T Nurden
Calcium influx is a determining factor of calpain activation and microparticle formation in platelets.
European journal of biochemistry / FEBS 1996;239(3):647-54.
1996: Jean-Max Pasquet; Florian Toti; A T Nurden; J Dachary-Prigent
Procoagulant activity and active calpain in platelet-derived microparticles.
Thrombosis research 1996;82(6):509-22.
1996: J Dachary-Prigent; Florian Toti; N Satta; Jean-Max Pasquet; A Uzan; Jean-Marie Freyssinet
Physiopathological significance of catalytic phospholipids in the generation of thrombin.
Seminars in thrombosis and hemostasis 1996;22(2):157-64.
1995: J Dachary-Prigent; Jean-Max Pasquet; Jean-Marie Freyssinet; A T Nurden
Calcium involvement in aminophospholipid exposure and microparticle formation during platelet activation: a study using Ca2+-ATPase inhibitors.
Biochemistry 1995;34(36):11625-34.
1993: J Dachary-Prigent; Jean-Marie Freyssinet; Jean-Max Pasquet; J C Carron; A T Nurden
Annexin V as a probe of aminophospholipid exposure and platelet membrane vesiculation: a flow cytometry study showing a role for free sulfhydryl groups.
Blood 1993;81(10):2554-65.