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Dinshaw Patel

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Jia Shen; Yan Wang; Yun Wu; Weiya Xia; Wei-Chao Chang; Chung-Hsuan Chen; Yi Du; Jennifer L Hsu; Longfei Huo; Brian P James; Yekaterina B Khotskaya; Yung Carmen Lam; Seung Oe Lim; Chang-Gong Liu; Xiuping Liu; Kotaro Nakanishi; Dinshaw J Patel; Mien-Chie Hung
EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2.
Marianna Teplova; Thomas Tuschl; Katharina Essig; Markus Hafner; Dmitri Teplov; Dinshaw J Patel
Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites.
VR Samygina; Rhoderick E Brown; Aintzane Cabo-Bilbao; Felipe Goni-de-Cerio; Julian G Molotkovsky; Borja Ochoa-Lizarralde; Dinshaw J Patel; Alexander N Popov; Lucy Malinina
Structural insights into lipid-dependent reversible dimerization of human GLTP.

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All Publications

2013: Jia Shen; Yan Wang; Yun Wu; Weiya Xia; Wei-Chao Chang; Chung-Hsuan Chen; Yi Du; Jennifer L Hsu; Longfei Huo; Brian P James; Yekaterina B Khotskaya; Yung Carmen Lam; Seung Oe Lim; Chang-Gong Liu; Xiuping Liu; Kotaro Nakanishi; Dinshaw J Patel; Mien-Chie Hung
EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2.
Nature 2013;497(7449):383-7.
2013: Marianna Teplova; Thomas Tuschl; Katharina Essig; Markus Hafner; Dmitri Teplov; Dinshaw J Patel
Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites.
Genes & development 2013;27(8):928-40.
2013: VR Samygina; Rhoderick E Brown; Aintzane Cabo-Bilbao; Felipe Goni-de-Cerio; Julian G Molotkovsky; Borja Ochoa-Lizarralde; Dinshaw J Patel; Alexander N Popov; Lucy Malinina
Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta crystallographica. Section D, Biological crystallography 2013;69(Pt 4):603-16.
2013: Qi Dai; Dinshaw J Patel; Aiming Ren; Artem A Serganov; Jakub O Westholm; Eric C Lai
The BEN domain is a novel sequence-specific DNA-binding domain conserved in neural transcriptional repressors.
Genes & development 2013;27(6):602-14.
2013: Irine Khutsishvili; Luis A Marky; Dinshaw J Patel; Conor Crean; Nicholas E Geacintov; Na Zhang; Vladimir Shafirovich
Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions.
Biochemistry 2013;52(8):1354-63.
2013: Yong-Seok Oh; Dinshaw J Patel; Ji-Seon Seo; Xiaozhu Zhang; Jung-Hyuck Ahn; Ilaria Ceglia; Brian T Chait; Pu Gao; Yong Kim; Ko-Woon Lee; Paul Greengard
SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action.
Cell 2013;152(4):831-43.
2013: Ling Cai; Wei-Yi Chen; Rui Lu; Dinshaw J Patel; Shira Rockowitz; Scott B Rothbart; Jikui Song; Brian D Strahl; Ashutosh Tripathy; Bowen Xu; Deyou Zheng; C David Allis; Gang Greg Wang
An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting.
Molecular cell 2013;49(3):571-82.
2013: Ravi Kanth Kamlekar; Roopa Kenoth; Lucy Malinina; Julian G Molotkovsky; Dinshaw J Patel; Helen M Pike; Franklyn G Prendergast; Dhirendra K Simanshu; Sergei Venyaminov; Yong-guang Gao; Rhoderick E Brown
The glycolipid transfer protein (GLTP) domain of phosphoinositol 4-phosphate adaptor protein-2 (FAPP2): structure drives preference for simple neutral glycosphingolipids.
Biochimica et biophysica acta 2013;1831(2):417-27.
2012: Vitaly Kuryavyi; Laty A Cahoon; H Steven Seifert; Dinshaw J Patel
RecA-binding pilE G4 sequence essential for pilin antigenic variation forms monomeric and 5' end-stacked dimeric parallel G-quadruplexes.
Structure (London, England : 1993) 2012;20(12):2090-102.
2012: Simon J Elsässer; Hongda Huang; Peter Lewis; C David Allis; Jason W Chin; Dinshaw J Patel
DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition.
Nature 2012;491(7425):560-5.
2012: Jiamu Du; Suhua Feng; Jonathan Hetzel; Yana V Bernatavichute; Elena Caro; Hang Gyeong Chin; Dinshaw J Patel; Sriharsa Pradhan; Hume Stroud; Jolyon Terragni; Andy Tu; Ajay A Vashisht; James A Wohlschlegel; Xuehua Zhong; Steven E Jacobsen
Dual binding of chromomethylase domains to H3K9me2-containing nucleosomes directs DNA methylation in plants.
Cell 2012;151(1):167-80.
2012: Kotaro Nakanishi; David P Bartel; David E Weinberg; Dinshaw J Patel
Structure of yeast Argonaute with guide RNA.
Nature 2012;486(7403):368-74.
2012: Aiming Ren; Kanagalaghatta R Rajashankar; Dinshaw J Patel
Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Nature 2012;486(7401):85-9.
2012: Alexander Serganov; Dinshaw J Patel
Molecular recognition and function of riboswitches.
Current opinion in structural biology 2012;22(3):279-86.
2012: Israel Ausin; Sophia D Española; Suhua Feng; Maxim V C Greenberg; Christopher J Hale; Tzuu-fen Lee; Blake C Meyers; Dinshaw J Patel; Dhirendra K Simanshu; Stacey A Simon; Ajay A Vashisht; James Wohlschlegel; Steven E Jacobsen
INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(22):8374-81.
2012: Alex J Kuo; Dinshaw J Patel; Jikui Song; Sayumi Yamazoe; James Kenneth Chen; Peggie Cheung; Satoko Ishibe-Murakami; Or Gozani
The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.
Nature 2012;484(7392):115-9.
2012: Jikui Song; Marianna Teplova; Satoko Ishibe-Murakami; Dinshaw J Patel
Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation.
Science (New York, N.Y.) 2012;335(6069):709-12.
2012: Jiamu Du; Hironori Funabiki; Alexander E Kelly; Dinshaw J Patel
Structural basis for recognition of H3T3ph and Smac/DIABLO N-terminal peptides by human Survivin.
Structure (London, England : 1993) 2012;20(1):185-95.
2012: Alexander Serganov; Dinshaw J Patel
Metabolite recognition principles and molecular mechanisms underlying riboswitch function.
Annual review of biophysics 2012;41():343-70.
2011: VR Samygina; Xiuhong Zhai; Rhoderick E Brown; Aintzane Cabo-Bilbao; Felipe Goni-de-Cerio; Julian G Molotkovsky; Borja Ochoa-Lizarralde; Dinshaw J Patel; Alexander N Popov; Lucy Malinina
Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure (London, England : 1993) 2011;19(11):1644-54.
2011: Dara A Reeves; Shantu Amin; Suse Broyde; Yuqin Cai; Ying Chen; Shuang Ding; Alexander Kolbanovskiy; Marina Kolbanovskiy; Konstantin Kropachev; Jacek Krzeminski; Hong Mu; Dinshaw J Patel; Nicholas E Geacintov
Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion-base stacking interactions.
Nucleic acids research 2011;39(20):8752-64.
2011: Olga Pikovskaya; Anna Polonskaia; Dinshaw J Patel; Alexander Serganov
Structural principles of nucleoside selectivity in a 2'-deoxyguanosine riboswitch.
Nature chemical biology 2011;7(10):748-55.
2011: Lili Huang; Satoko Ishibe-Murakami; Dinshaw J Patel; Alexander Serganov
Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(36):14801-6.
2011: Marianna Teplova; Lara Wohlbold; Elisa Izaurralde; Nyan W Khin; Dinshaw J Patel
Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
Nature structural & molecular biology 2011;18(9):990-8.
2011: David E Weinberg; Kotaro Nakanishi; Dinshaw J Patel; David P Bartel
The inside-out mechanism of Dicers from budding yeasts.
Cell 2011;146(2):262-76.
2011: Eerappa Rajakumara; Yujiang Geno Shi; Zhentian Wang; Feizhen Wu; Yanhui Xu; Hao Chen; Rui Guo; Lulu Hu; Fei Lan; Haitao Li; Yan Lin; Honghui Ma; Dinshaw J Patel; Yang Shi
PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression.
Molecular cell 2011;43(2):275-84.
2011: Marianna Teplova; Jikui Song; Alexei Teplov; Ruben Abagyan; Stephen K Burley; Jennifer C Darnell; Robert B Darnell; Min Lu; Lucy Malinina; Kiran Musunuru; Dinshaw J Patel
Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
Structure (London, England : 1993) 2011;19(7):930-44.
2011: Shigeki Iwase; Peter Lewis; Haitao Li; Dinshaw J Patel; David J Picketts; Ting Ren; C David Allis; Jesse C Cochrane; Sharmistha Ghosh; Bin Xiang; Yang Shi
ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome.
Nature structural & molecular biology 2011;18(7):769-76.
2011: Anh Tuân Phan; Anna Polonskaia; Tanya Raslin; Alexander Serganov; Cynthia Chen; David Clain; Jennifer C Darnell; Robert B Darnell; Serge Ilin; Vitaly Kuryavyi; Ananya Majumdar; Dinshaw J Patel
Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction.
Nature structural & molecular biology 2011;18(7):796-804.
2011: Roopa Kenoth; Lucy Malinina; Julian G Molotkovsky; Dinshaw J Patel; Franklyn G Prendergast; Dhirendra K Simanshu; Sergei Venyaminov; Yongguang Gao; Ravi Kanth Kamlekar; Rhoderick E Brown
Conformational folding and stability of the HET-C2 glycolipid transfer protein fold: does a molten globule-like state regulate activity?
Biochemistry 2011;50(23):5163-71.
2011: Olga Rechkoblit; James C Delaney; John M Essigmann; Dinshaw J Patel
Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure (London, England : 1993) 2011;19(6):821-32.
2011: Yuan Tian; Dhirendra K Simanshu; Manuel Ascano; Ruben Diaz-Avalos; Ah Young Park; Stefan A Juranek; William J Rice; Qian Yin; Carol V Robinson; Thomas Tuschl; Dinshaw J Patel
Multimeric assembly and biochemical characterization of the Trax-translin endonuclease complex.
Nature structural & molecular biology 2011;18(6):658-64.
2011: Alexander J Ruthenburg; Haitao Li; Thomas A Milne; Scott Dewell; Robert K McGinty; Melanie Yuen; Beatrix Ueberheide; Yali Dou; Tom W Muir; Dinshaw J Patel; C David Allis
Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions.
Cell 2011;145(5):692-706.
2011: Zhanxin Wang; Dinshaw J Patel
Combinatorial readout of dual histone modifications by paired chromatin-associated modules.
The Journal of biological chemistry 2011;286(21):18363-8.
2011: Prabodhika R Mallikaratchy; Alessandro Ruggiero; Jeffrey R Gardner; Vitaly Kuryavyi; William F Maguire; Mark L Heaney; Michael R McDevitt; Dinshaw J Patel; David A Scheinberg
A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia.
Nucleic acids research 2011;39(6):2458-69.
2011: Jikui Song; Olga Rechkoblit; Timothy H Bestor; Dinshaw J Patel
Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.
Science (New York, N.Y.) 2011;331(6020):1036-40.
2011: Yuan Tian; Dhirendra K Simanshu; Jin-Biao Ma; Dinshaw J Patel
Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(3):903-10.
2011: Eerappa Rajakumara; Julie A Law; Dhirendra K Simanshu; Philipp Voigt; Lianna M Johnson; Danny Reinberg; Dinshaw J Patel; Steven E Jacobsen
A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes & development 2011;25(2):137-52.
2010: Wen-Wei Tsai; Zhanxin Wang; Teresa T Yiu; Kadir C Akdemir; Weiya Xia; Stefan Winter; Cheng-Yu Tsai; Xiaobing Shi; Dirk Schwarzer; William Plunkett; Bruce Aronow; Or Gozani; Wolfgang Fischle; Mien-Chie Hung; Dinshaw J Patel; Michelle Craig Barton
TRIM24 links a non-canonical histone signature to breast cancer.
Nature 2010;468(7326):927-32.
2010: Lili Huang; Alexander Serganov; Dinshaw J Patel
Structural insights into ligand recognition by a sensing domain of the cooperative glycine riboswitch.
Molecular cell 2010;40(5):774-86.
2010: Ravi Kanth Kamlekar; Yongguang Gao; Roopa Kenoth; Julian G Molotkovsky; Franklyn G Prendergast; Lucy Malinina; Dinshaw J Patel; William S Wessels; Sergei Venyaminov; Rhoderick E Brown
Human GLTP: Three distinct functions for the three tryptophans in a novel peripheral amphitropic fold.
Biophysical journal 2010;99(8):2626-35.
2010: Marianna Teplova; Jikui Song; Hai Yan Gaw; Alexei Teplov; Dinshaw J Patel
Structural insights into RNA recognition by the alternate-splicing regulator CUG-binding protein 1.
Structure (London, England : 1993) 2010;18(10):1364-77.
2010: Vitaly Kuryavyi; Anh Tuân Phan; Dinshaw J Patel
Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter.
Nucleic acids research 2010;38(19):6757-73.
2010: Yanli Wang; Janos Ludwig; Christine Schuberth; Marion Goldeck; Martin Schlee; Haitao Li; Stefan Juranek; Gang Sheng; Ronald Micura; Thomas Tuschl; Gunther Hartmann; Dinshaw J Patel
Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I.
Nature structural & molecular biology 2010;17(7):781-7.
2010: Zhanxin Wang; Jikui Song; Thomas A Milne; Gang G Wang; Haitao Li; C David Allis; Dinshaw J Patel
Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell 2010;141(7):1183-94.
2010: Suse Broyde; Dinshaw J Patel
DNA repair: How to accurately bypass damage.
Nature 2010;465(7301):1023-4.
2010: Yuqin Cai; Konstantin Kropachev; Rong Xu; Yijin Tang; Marina Kolbanovskii; Alexander Kolbanovskii; Shantu Amin; Dinshaw J Patel; Suse Broyde; Nicholas E Geacintov
Distant neighbor base sequence context effects in human nucleotide excision repair of a benzo[a]pyrene-derived DNA lesion.
Journal of molecular biology 2010;399(3):397-409.
2010: Roopa Kenoth; Dhirendra K Simanshu; Ravi Kanth Kamlekar; Helen M Pike; Julian G Molotkovsky; Linda M Benson; H Robert Bergen; Franklyn G Prendergast; Lucy Malinina; Sergei Venyaminov; Dinshaw J Patel; Rhoderick E Brown
Structural determination and tryptophan fluorescence of heterokaryon incompatibility C2 protein (HET-C2), a fungal glycolipid transfer protein (GLTP), provide novel insights into glycolipid specificity and membrane interaction by the GLTP fold.
The Journal of biological chemistry 2010;285(17):13066-78.
2010: Olga Rechkoblit; Alexander Kolbanovskiy; Lucy Malinina; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4.
Nature structural & molecular biology 2010;17(3):379-88.
2010: Vitaly Kuryavyi; Dinshaw J Patel
Solution structure of a unique G-quadruplex scaffold adopted by a guanosine-rich human intronic sequence.
Structure (London, England : 1993) 2010;18(1):73-82.
2010: Yuqin Cai; Dinshaw J Patel; Suse Broyde; Nicholas E Geacintov
Base sequence context effects on nucleotide excision repair.
Journal of nucleic acids 2010;2010():.
2009: Yanli Wang; Stefan Juranek; Haitao Li; Gang Sheng; Greg S Wardle; Thomas Tuschl; Dinshaw J Patel
Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature 2009;461(7265):754-61.
2009: Alexander Serganov; Dinshaw J Patel
Amino acid recognition and gene regulation by riboswitches.
Biochimica et biophysica acta 2009;1789(9-10):592-611.
2009: Na Zhang; Shuang Ding; Alexander Kolbanovskiy; Anant Shastry; Vladimir A Kuzmin; Judy L Bolton; Dinshaw J Patel; Suse Broyde; Nicholas E Geacintov
NMR and computational studies of stereoisomeric equine estrogen-derived DNA cytidine adducts in oligonucleotide duplexes: opposite orientations of diastereomeric forms.
Biochemistry 2009;48(30):7098-109.
2009: Gang G Wang; Jikui Song; Zhanxin Wang; Holger L Dormann; Fabio Casadio; Haitao Li; Jun-Li Luo; Dinshaw J Patel; C David Allis
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature 2009;459(7248):847-51.
2009: Eric Westhof; Dinshaw J Patel
Nucleic acids: how high resolution structural biology help us to understand Darwinian evolution.
Current opinion in structural biology 2009;19(3):235-8.
2009: Xiuhong Zhai; Margarita L Malakhova; Helen M Pike; Linda M Benson; H Robert Bergen; István P Sugár; Lucy Malinina; Dinshaw J Patel; Rhoderick E Brown
Glycolipid acquisition by human glycolipid transfer protein dramatically alters intrinsic tryptophan fluorescence: insights into glycolipid binding affinity.
The Journal of biological chemistry 2009;284(20):13620-8.
2009: Olga Rechkoblit; Lucy Malinina; Yuan Cheng; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure (London, England : 1993) 2009;17(5):725-36.
2009: Haitao Li; Mohammad R Motamedi; Calvin K Yip; Zhanxin Wang; Thomas Walz; Dinshaw J Patel; Danesh Moazed
An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Molecular cell 2009;34(2):155-67.
2009: Kah Wai Lim; Samir Amrane; Serge Bouaziz; weixin Xu; Yuguang Mu; Dinshaw J Patel; Kim Ngoc Luu; Anh Tuân Phan
Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers.
Journal of the American Chemical Society 2009;131(12):4301-9.
2009: Konstantin Kropachev; Marina Kolbanovskii; Yuqin Cai; Fabian Rodríguez; Alexander Kolbanovskii; Yang Liu; Lu Zhang; Shantu Amin; Dinshaw J Patel; Suse Broyde; Nicholas E Geacintov
The sequence dependence of human nucleotide excision repair efficiencies of benzo[a]pyrene-derived DNA lesions: insights into the structural factors that favor dual incisions.
Journal of molecular biology 2009;386(5):1193-203.
2009: Alexander Serganov; Lili Huang; Dinshaw J Patel
Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch.
Nature 2009;458(7235):233-7.
2009: Quan Zhao; Gerhard Rank; Yuen T Tan; Haitao Li; Robert L Moritz; Richard J Simpson; Loretta Cerruti; David J Curtis; Dinshaw J Patel; C David Allis; John M Cunningham; Stephen M Jane
PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.
Nature structural & molecular biology 2009;16(3):304-11.
2009: Yuqin Cai; Dinshaw J Patel; Nicholas E Geacintov; Suse Broyde
Differential nucleotide excision repair susceptibility of bulky DNA adducts in different sequence contexts: hierarchies of recognition signals.
Journal of molecular biology 2009;385(1):30-44.
2009: Olga Pikovskaya; Artem A Serganov; Ann Polonskaia; Alexander Serganov; Dinshaw J Patel
Preparation and crystallization of riboswitch-ligand complexes.
Methods in molecular biology (Clifton, N.J.) 2009;540():115-28.
2009: Andrew Xiao; Haitao Li; David Shechter; Sung Hee Ahn; Laura A Fabrizio; Hediye Erdjument-Bromage; Satoko Ishibe-Murakami; Bin Wang; Paul Tempst; Kay Hofmann; Dinshaw J Patel; Stephen J Elledge; C David Allis
WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity.
Nature 2009;457(7225):57-62.
2008: Yanli Wang; Stefan Juranek; Haitao Li; Gang Sheng; Thomas Tuschl; Dinshaw J Patel
Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex.
Nature 2008;456(7224):921-6.
2008: Marianna Teplova; Dinshaw J Patel
Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1.
Nature structural & molecular biology 2008;15(12):1343-51.
2008: Yanli Wang; Gang Sheng; Stefan Juranek; Thomas Tuschl; Dinshaw J Patel
Structure of the guide-strand-containing argonaute silencing complex.
Nature 2008;456(7219):209-13.
2008: Alexander Serganov; Lili Huang; Dinshaw J Patel
Structural insights into amino acid binding and gene control by a lysine riboswitch.
Nature 2008;455(7217):1263-7.
2008: Suse Broyde; Lihua Wang; Olga Rechkoblit; Nicholas E Geacintov; Dinshaw J Patel
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases.
Trends in biochemical sciences 2008;33(5):209-19.
2008: Alexander Serganov; Dinshaw J Patel
Towards deciphering the principles underlying an mRNA recognition code.
Current opinion in structural biology 2008;18(1):120-9.
2008: Dinshaw J Patel
Structural biology of riboswitch-mediated gene regulation and argonaute-mediated gene silencing.
Nucleic acids symposium series (2004) 2008;(52):1.
2008: Suse Broyde; Lihua Wang; Ling Zhang; Olga Rechkoblit; Nicholas E Geacintov; Dinshaw J Patel
DNA adduct structure-function relationships: comparing solution with polymerase structures.
Chemical research in toxicology 2008;21(1):45-52.
2007: Alexander J Ruthenburg; Haitao Li; Dinshaw J Patel; C David Allis
Multivalent engagement of chromatin modifications by linked binding modules.
Nature reviews. Molecular cell biology 2007;8(12):983-94.
2007: Haitao Li; Wolfgang Fischle; Wooikoon Wang; Elizabeth M Duncan; Lena Liang; Satoko Murakami-Ishibe; C David Allis; Dinshaw J Patel
Structural basis for lower lysine methylation state-specific readout by MBT repeats of L3MBTL1 and an engineered PHD finger.
Molecular cell 2007;28(4):677-91.
2007: Yuqin Cai; Dinshaw J Patel; Nicholas E Geacintov; Suse Broyde
Dynamics of a benzo[a]pyrene-derived guanine DNA lesion in TGT and CGC sequence contexts: enhanced mobility in TGT explains conformational heterogeneity, flexible bending, and greater susceptibility to nucleotide excision repair.
Journal of molecular biology 2007;374(2):292-305.
2007: SEAN TAVERNA; Haitao Li; Alexander J Ruthenburg; C David Allis; Dinshaw J Patel
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers.
Nature structural & molecular biology 2007;14(11):1025-40.
2007: Alexander Serganov; Dinshaw J Patel
Ribozymes, riboswitches and beyond: regulation of gene expression without proteins.
Nature reviews. Genetics 2007;8(10):776-90.
2007: Thomas Hermann; Valentina Tereshko; Eugene Skripkin; Dinshaw J Patel
Apramycin recognition by the human ribosomal decoding site.
Blood cells, molecules & diseases 2007;38(3):193-8.
2007: Anh Tuân Phan; Vitaly Kuryavyi; Sarah Burge; Stephen Neidle; Dinshaw J Patel
Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter.
Journal of the American Chemical Society 2007;129(14):4386-92.
2007: Dinshaw J Patel; Anh Tuân Phan; Vitaly Kuryavyi
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.
Nucleic acids research 2007;35(22):7429-55.
2007: Anh Tuân Phan; Vitaly Kuryavyi; Kim Ngoc Luu; Dinshaw J Patel
Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.
Nucleic acids research 2007;35(19):6517-25.
2007: Maximillian H Bailor; Catherine Musselman; Alexandar L Hansen; Kush Gulati; Dinshaw J Patel; Hashim M Al-Hashimi
Characterizing the relative orientation and dynamics of RNA A-form helices using NMR residual dipolar couplings.
Nature protocols 2007;2(6):1536-46.
2007: Fabián A Rodríguez; Yuqin Cai; Chin Lin; Yijin Tang; Alexander Kolbanovskiy; Shantu Amin; Dinshaw J Patel; Suse Broyde; Nicholas E Geacintov
Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot context.
Nucleic acids research 2007;35(5):1555-68.
2006: SEAN TAVERNA; Sergey Ilin; Richard S Rogers; Jason Tanny; Heather Lavender; Haitao Li; Lindsey Baker; John Boyle; Lauren P Blair; Brian T Chait; Dinshaw J Patel; John D Aitchison; Alan J Tackett; C David Allis
Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs.
Molecular cell 2006;24(5):785-96.
2006: Xiuren Zhang; Yu-Ren Yuan; Yi Pei; Shih-Shun Lin; Thomas Tuschl; Dinshaw J Patel; Nam-Hai Chua
Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense.
Genes & development 2006;20(23):3255-68.
2006: Lucy Malinina; Margarita L Malakhova; Alex T Kanack; Min Lu; Ruben Abagyan; Rhoderick Brown; Dinshaw J Patel
The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure.
PLoS biology 2006;4(11):e362.
2006: Yu-Ren Yuan; Yi Pei; Hong-Ying Chen; Thomas Tuschl; Dinshaw J Patel
A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA.
Structure (London, England : 1993) 2006;14(10):1557-65.
2006: Kim Ngoc Luu; Anh Tuân Phan; Vitaly Kuryavyi; Laurent Lacroix; Dinshaw J Patel
Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffold.
Journal of the American Chemical Society 2006;128(30):9963-70.
2006: Alexander J Ruthenburg; Wooikoon Wang; Daina M Graybosch; Haitao Li; C David Allis; Dinshaw J Patel; Gregory L Verdine
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nature structural & molecular biology 2006;13(8):704-12.
2006: Haitao Li; Sergey Ilin; Wooikoon Wang; Elizabeth M Duncan; Joanna Wysocka; C David Allis; Dinshaw J Patel
Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature 2006;442(7098):91-5.
2006: Alexander Serganov; Anna Polonskaia; Anh Tuân Phan; Ronald R Breaker; Dinshaw J Patel
Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch.
Nature 2006;441(7097):1167-71.
2006: Anh Tuân Phan; Vitaly Kuryavyi; Dinshaw J Patel
DNA architecture: from G to Z.
Current opinion in structural biology 2006;16(3):288-98.
2006: Richard Wombacher; Sonja Keiper; Sandra Suhm; Alexander Serganov; Dinshaw J Patel; Andres Jäschke
Control of stereoselectivity in an enzymatic reaction by backdoor access.
Angewandte Chemie (International ed. in English) 2006;45(15):2469-72.
2006: Marianna Teplova; Yu-Ren Yuan; Anh Tuân Phan; Lucy Malinina; Sergey Ilin; Alexei Teplov; Dinshaw J Patel
Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen.
Molecular cell 2006;21(1):75-85.
2006: Dinshaw J Patel; Jin-Biao Ma; Yu-Ren Yuan; Keqiong Ye; Yi Pei; Vitaly Kuryavyi; Lucy Malinina; Gunter Meister; Thomas Tuschl
Structural biology of RNA silencing and its functional implications.
Cold Spring Harbor symposia on quantitative biology 2006;71():81-93.
2006: Anh Tuân Phan; Kim Ngoc Luu; Dinshaw J Patel
Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution.
Nucleic acids research 2006;34(19):5715-9.
2006: Ling Zhang; Olga Rechkoblit; Lihua Wang; Dinshaw J Patel; Robert Shapiro; Suse Broyde
Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies.
Nucleic acids research 2006;34(11):3326-37.
2006: Olga Rechkoblit; Lucy Malinina; Yuan Cheng; Vitaly Kuryavyi; Suse Broyde; Nicholas E Geacintov; Dinshaw J Patel
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.
PLoS biology 2006;4(1):e11.
2005: Na Zhang; Anh Tuân Phan; Dinshaw J Patel
(3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex.
Journal of the American Chemical Society 2005;127(49):17277-85.
2005: Keqiong Ye; Dinshaw J Patel
RNA silencing suppressor p21 of Beet yellows virus forms an RNA binding octameric ring structure.
Structure (London, England : 1993) 2005;13(9):1375-84.
2005: Yu-Ren Yuan; Yi Pei; Jin-Biao Ma; Vitaly Kuryavyi; Maria Zhadina; Gunter Meister; Hong-Ying Chen; Zbigniew Dauter; Thomas Tuschl; Dinshaw J Patel
Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage.
Molecular cell 2005;19(3):405-19.
2005: Anh Tuân Phan; Vitaly Kuryavyi; Hai Yan Gaw; Dinshaw J Patel
Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Nature chemical biology 2005;1(3):167-73.
2005: Margarita L Malakhova; Lucy Malinina; Helen M Pike; Alexander T Kanack; Dinshaw J Patel; Rhoderick Brown
Point mutational analysis of the liganding site in human glycolipid transfer protein. Functionality of the complex.
The Journal of biological chemistry 2005;280(28):26312-20.
2005: Stephen W Pitt; Qi Zhang; Dinshaw J Patel; Hashim M Al-Hashimi
Evidence that electrostatic interactions dictate the ligand-induced arrest of RNA global flexibility.
Angewandte Chemie (International ed. in English) 2005;44(22):3412-5.
2005: Jin-Biao Ma; Yu-Ren Yuan; Gunter Meister; Yi Pei; Thomas Tuschl; Dinshaw J Patel
Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.
Nature 2005;434(7033):666-70.
2005: Na Zhang; Chin Lin; Xuanwei Huang; Alexander Kolbanovskiy; Brian E Hingerty; Shantu Amin; Suse Broyde; Nicholas E Geacintov; Dinshaw J Patel
Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement.
Journal of molecular biology 2005;346(4):951-65.
2005: Lihua Wang; Min Wu; Shi Fang Yan; Dinshaw J Patel; Nicholas E Geacintov; Suse Broyde
Accommodation of a 1S-(-)-benzo[c]phenanthrenyl-N6-dA adduct in the Y-family Dpo4 DNA polymerase active site: structural insights through molecular dynamics simulations.
Chemical research in toxicology 2005;18(3):441-56.
2005: Alexander Serganov; Sonja Keiper; Lucy Malinina; Valentina Tereshko; Eugene Skripkin; Claudia Hoebartner; Anna Polonskaia; Anh Tuân Phan; Richard Wombacher; Ronald Micura; Zbigniew Dauter; Andres Jäschke; Dinshaw J Patel
Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nature structural & molecular biology 2005;12(3):218-24.
2005: Anh Tuân Phan; Vitaly Kuryavyi; Jin-Biao Ma; Aurélie Faure; Marie-Line Andréola; Dinshaw J Patel
An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(3):634-9.
2004: Alexander Serganov; Yu-Ren Yuan; Olga Pikovskaya; Anna Polonskaia; Lucy Malinina; Anh Tuân Phan; Claudia Hoebartner; Ronald Micura; Ronald R Breaker; Dinshaw J Patel
Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs.
Chemistry & biology 2004;11(12):1729-41.
2004: Yuan Cheng; Dinshaw J Patel
Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP.
Journal of molecular biology 2004;343(2):305-12.
2004: Yuan Cheng; Sonia M Sequeira; Lucy Malinina; Valentina Tereshko; Thomas H Söllner; Dinshaw J Patel
Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain.
Protein science : a publication of the Protein Society 2004;13(10):2665-72.
2004: Min Wu; Shi Fang Yan; Jian Tan; Dinshaw J Patel; Nicholas E Geacintov; Suse Broyde
Conformational searches elucidate effects of stereochemistry on structures of deoxyadenosine covalently bound to tumorigenic metabolites of benzo[C] phenanthrene.
Frontiers in bioscience : a journal and virtual library 2004;9():2807-18.
2004: Lucy Malinina; Margarita L Malakhova; Alexei Teplov; Rhoderick Brown; Dinshaw J Patel
Structural basis for glycosphingolipid transfer specificity.
Nature 2004;430(7003):1048-53.
2004: Anh Tuân Phan; Yasha S Modi; Dinshaw J Patel
Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter.
Journal of the American Chemical Society 2004;126(28):8710-6.
2004: Jin-Biao Ma; Keqiong Ye; Dinshaw J Patel
Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain.
Nature 2004;429(6989):318-22.
2004: Chantal Ehresmann; Bernard Ehresmann; Vincent Olieric; Philippe Dumas; Maria Garber; Nathalie Mathy; Alexei Nikulin; Claude Portier; Dinshaw J Patel; Alexander Serganov
Molecular mimicry in translational regulation: the case of ribosomal protein S15.
RNA biology 2004;1(1):66-73.
2004: Nathalie Mathy; Olivier Pellegrini; Alexander Serganov; Dinshaw J Patel; Chantal Ehresmann; Claude Portier
Specific recognition of rpsO mRNA and 16S rRNA by Escherichia coli ribosomal protein S15 relies on both mimicry and site differentiation.
Molecular microbiology 2004;52(3):661-75.
2004: Yuan Cheng; Dinshaw J Patel
An efficient system for small protein expression and refolding.
Biochemical and biophysical research communications 2004;317(2):401-5.
2004: Anh Tuân Phan; Yasha S Modi; Dinshaw J Patel
Two-repeat Tetrahymena telomeric d(TGGGGTTGGGGT) Sequence interconverts between asymmetric dimeric G-quadruplexes in solution.
Journal of molecular biology 2004;338(1):93-102.
2004: Stephen W Pitt; Ananya Majumdar; Alexander Serganov; Dinshaw J Patel; Hashim M Al-Hashimi
Argininamide binding arrests global motions in HIV-1 TAR RNA: comparison with Mg2+-induced conformational stabilization.
Journal of molecular biology 2004;338(1):7-16.
2003: Keqiong Ye; Lucy Malinina; Dinshaw J Patel
Recognition of small interfering RNA by a viral suppressor of RNA silencing.
Nature 2003;426(6968):874-8.
2003: Anh Tuân Phan; Dinshaw J Patel
Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics.
Journal of the American Chemical Society 2003;125(49):15021-7.
2003: Ulrich Stelzl; Janice M Zengel; Marina Tovbina; Marquis Walker; Knud H Nierhaus; Lasse Lindahl; Dinshaw J Patel
RNA-structural mimicry in Escherichia coli ribosomal protein L4-dependent regulation of the S10 operon.
The Journal of biological chemistry 2003;278(30):28237-45.
2003: Wooi Koon Wang; Valentina Tereshko; Piernicola Boccuni; Donal MacGrogan; Stephen D Nimer; Dinshaw J Patel
Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets.
Structure (London, England : 1993) 2003;11(7):775-89.
2003: Hashim M Al-Hashimi; Stephen W Pitt; Ananya Majumdar; Weijun Xu; Dinshaw J Patel
Mg2+-induced variations in the conformation and dynamics of HIV-1 TAR RNA probed using NMR residual dipolar couplings.
Journal of molecular biology 2003;329(5):867-73.
2003: Alexander Serganov; Anna Polonskaia; Bernard Ehresmann; Chantal Ehresmann; Dinshaw J Patel
Ribosomal protein S15 represses its own translation via adaptation of an rRNA-like fold within its mRNA.
The EMBO journal 2003;22(8):1898-908.
2003: Shixiang Yan; Min Wu; Dinshaw J Patel; Nicholas E Geacintov; Suse Broyde
Simulating structural and thermodynamic properties of carcinogen-damaged DNA.
Biophysical journal 2003;84(4):2137-48.
2003: Valentina Tereshko; Eugene Skripkin; Dinshaw J Patel
Encapsulating streptomycin within a small 40-mer RNA.
Chemistry & biology 2003;10(2):175-87.
2002: Arthur G Palmer; Dinshaw J Patel
Kurt Wüthrich and NMR of biological macromolecules.
Structure (London, England : 1993) 2002;10(12):1603-4.
2002: Nicholas E Geacintov; Suse Broyde; Tonko Buterin; Hanspeter Naegeli; Min Wu; Shixiang Yan; Dinshaw J Patel
Thermodynamic and structural factors in the removal of bulky DNA adducts by the nucleotide excision repair machinery.
Biopolymers 2002;65(3):202-10.
2002: Keqiong Ye; Alexander Serganov; weidong hu; Maria Garber; Dinshaw J Patel
Ribosome-associated factor Y adopts a fold resembling a double-stranded RNA binding domain scaffold.
European journal of biochemistry / FEBS 2002;269(21):5182-91.
2002: Anh Tuân Phan; Dinshaw J Patel
Differentiation between unlabeled and very-low-level fully 15N,13C-labeled nucleotides for resonance assignments in nucleic acids.
Journal of biomolecular NMR 2002;23(4):257-62.
2002: Min Wu; Shixiang Yan; Dinshaw J Patel; Nicholas E Geacintov; Suse Broyde
Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability.
Nucleic acids research 2002;30(15):3422-32.
2002: Dinshaw J Patel
Structural biology: a molecular propeller.
Nature 2002;417(6891):807-8.
2002: Hashim M Al-Hashimi; Andrey Gorin; Ananya Majumdar; Yuying Gosser; Dinshaw J Patel
Towards structural genomics of RNA: rapid NMR resonance assignment and simultaneous RNA tertiary structure determination using residual dipolar couplings.
Journal of molecular biology 2002;318(3):637-49.
2002: Anh Tuân Phan; Dinshaw J Patel
A site-specific low-enrichment (15)N,(13)C isotope-labeling approach to unambiguous NMR spectral assignments in nucleic acids.
Journal of the American Chemical Society 2002;124(7):1160-1.
2002: Hashim M Al-Hashimi; Yuying Gosser; Andrey Gorin; weidong hu; Ananya Majumdar; Dinshaw J Patel
Concerted motions in HIV-1 TAR RNA may allow access to bound state conformations: RNA dynamics from NMR residual dipolar couplings.
Journal of molecular biology 2002;315(2):95-102.
2002: Hashim M Al-Hashimi; Dinshaw J Patel
Residual dipolar couplings: synergy between NMR and structural genomics.
Journal of biomolecular NMR 2002;22(1):1-8.
2002: Ananya Majumdar; Dinshaw J Patel
Identifying hydrogen bond alignments in multistranded DNA architectures by NMR.
Accounts of chemical research 2002;35(1):1-11.
2001: Ananya Majumdar; Yuying Gosser; Dinshaw J Patel
1H-1H correlations across N-H...N hydrogen bonds in nucleic acids.
Journal of biomolecular NMR 2001;21(4):289-306.
2001: Min Wu; Shixiang Yan; Dinshaw J Patel; Nicholas E Geacintov; Suse Broyde
Cyclohexene ring and Fjord region twist inversion in stereoisomeric DNA adducts of enantiomeric benzo[c]phenanthrene diol epoxides.
Chemical research in toxicology 2001;14(12):1629-42.
2001: Sylvie Nonin-Lecomte or Nonin; C H Lin; Dinshaw J Patel
Additional hydrogen bonds and base-pair kinetics in the symmetrical AMP-DNA aptamer complex.
Biophysical journal 2001;81(6):3422-31.
2001: Na Zhang; Andrey Gorin; Ananya Majumdar; A Kettani; N Chernichenko; Eugene Skripkin; Dinshaw J Patel
Dimeric DNA quadruplex containing major groove-aligned A-T-A-T and G-C-G-C tetrads stabilized by inter-subunit Watson-Crick A-T and G-C pairs.
Journal of molecular biology 2001;312(5):1073-88.
2001: G Subramaniam; Manuel Paz; Gopinatha Suresh ; A Das; Yolanda Palom; Cristina Clement; Dinshaw J Patel; Maria Tomasz
Solution structure of a guanine-N7-linked complex of the mitomycin C metabolite 2,7-diaminomitosene and DNA. Basis of sequence selectivity.
Biochemistry 2001;40(35):10473-84.
2001: Na Zhang; Andrey Gorin; Ananya Majumdar; A Kettani; N Chernichenko; Eugene Skripkin; Dinshaw J Patel
V-shaped scaffold: a new architectural motif identified in an A x (G x G x G x G) pentad-containing dimeric DNA quadruplex involving stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads.
Journal of molecular biology 2001;311(5):1063-79.
2001: Vitaly Kuryavyi; Ananya Majumdar; A Shallop; N Chernichenko; Eugene Skripkin; R Jones; Dinshaw J Patel
A double chain reversal loop and two diagonal loops define the architecture of a unimolecular DNA quadruplex containing a pair of stacked G(syn)-G(syn)-G(anti)-G(anti) tetrads flanked by a G-(T-T) Triad and a T-T-T triple.
Journal of molecular biology 2001;310(1):181-94.
2001: Hashim M Al-Hashimi; JR Tolman; Ananya Majumdar; Andrey Gorin; Dinshaw J Patel
Determining stoichiometry in homomultimeric nucleic acid complexes using magnetic field induced residual dipolar couplings.
Journal of the American Chemical Society 2001;123(24):5806-7.
2001: weidong hu; Yuying Gosser; Weijun Xu; Dinshaw J Patel
Novel 2D and 3D multiple-quantum bi-directional HCNCH experiments for the correlation of ribose and base protons/carbons in 13C/15N labeled RNA.
Journal of biomolecular NMR 2001;20(2):167-72.
2001: Hashim M Al-Hashimi; Andrey Gorin; Ananya Majumdar; Dinshaw J Patel
Alignment of the HTLV-I Rex peptide bound to its target RNA aptamer from magnetic field-induced residual dipolar couplings and intermolecular hydrogen bonds.
Journal of the American Chemical Society 2001;123(13):3179-80.
2001: C H Lin; X Huang; A Kolbanovskii; Brian E Hingerty; Shantu Amin; Suse Broyde; Nicholas E Geacintov; Dinshaw J Patel
Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.
Journal of molecular biology 2001;306(5):1059-80.
2001: Ananya Majumdar; A Kettani; Eugene Skripkin; Dinshaw J Patel
Pulse sequences for detection of NH2...N hydrogen bonds in sheared G . A mismatches via remote, non-exchangeable protons.
Journal of biomolecular NMR 2001;19(2):103-13.
2001: Yuying Gosser; T Hermann; Ananya Majumdar; weidong hu; R Frederick; F Jiang; Weijun Xu; Dinshaw J Patel
Peptide-triggered conformational switch in HIV-1 RRE RNA complexes.
Nature structural biology 2001;8(2):146-50.
2001: Hashim M Al-Hashimi; Ananya Majumdar; Andrey Gorin; A Kettani; Eugene Skripkin; Dinshaw J Patel
Field- and phage-induced dipolar couplings in a homodimeric DNA quadruplex: relative orientation of G.(C-A) triad and G-tetrad motifs and direct determination of C2 symmetry axis orientation.
Journal of the American Chemical Society 2001;123(4):633-40.
2000: S Shimotakahara; Andrey Gorin; Alexander Kolbanovskiy; A Kettani; Brian E Hingerty; Shantu Amin; Suse Broyde; Nicholas E Geacintov; Dinshaw J Patel
Accomodation of S-cis-tamoxifen-N(2)-guanine adduct within a bent and widened DNA minor groove.
Journal of molecular biology 2000;302(2):377-93.
2000: A Kettani; G Basu; Andrey Gorin; Ananya Majumdar; Eugene Skripkin; Dinshaw J Patel
A two-stranded template-based approach to G.(C-A) triad formation: designing novel structural elements into an existing DNA framework.
Journal of molecular biology 2000;301(1):129-46.
2000: A Liu; weidong hu; Ananya Majumdar; Michael K Rosen; Dinshaw J Patel
NMR detection of side chain-side chain hydrogen bonding interactions in 13C/15N-labeled proteins.
Journal of biomolecular NMR 2000;17(4):305-10.
2000: A Liu; weidong hu; Ananya Majumdar; Michael K Rosen; Dinshaw J Patel
Detection of very weak side chain-main chain hydrogen bonding interactions in medium-size 13C/15N-labeled proteins by sensitivity-enhanced NMR spectroscopy.
Journal of biomolecular NMR 2000;17(1):79-82.
2000: A Kettani; Andrey Gorin; Ananya Majumdar; T Hermann; Eugene Skripkin; H Zhao; R Jones; Dinshaw J Patel
A dimeric DNA interface stabilized by stacked A.(G.G.G.G).A hexads and coordinated monovalent cations.
Journal of molecular biology 2000;297(3):627-44.
2000: T Hermann; Dinshaw J Patel
RNA bulges as architectural and recognition motifs.
Structure (London, England : 1993) 2000;8(3):R47-54.
2000: Dinshaw J Patel; A K Suri
Structure, recognition and discrimination in RNA aptamer complexes with cofactors, amino acids, drugs and aminoglycoside antibiotics.
Journal of biotechnology 2000;74(1):39-60.
2000: T Hermann; Dinshaw J Patel
Adaptive recognition by nucleic acid aptamers.
Science (New York, N.Y.) 2000;287(5454):820-5.
2000: Vitaly Kuryavyi; A Kettani; W Wang; R Jones; Dinshaw J Patel
A diamond-shaped zipper-like DNA architecture containing triads sandwiched between mismatches and tetrads.
Journal of molecular biology 2000;295(3):455-69.
1999: F Jiang; Andrey Gorin; weidong hu; Ananya Majumdar; Scott Baskerville; Weijun Xu; A Ellington; Dinshaw J Patel
Anchoring an extended HTLV-1 Rex peptide within an RNA major groove containing junctional base triples.
Structure (London, England : 1993) 1999;7(12):1461-72.
1999: T Hermann; Dinshaw J Patel
Stitching together RNA tertiary architectures.
Journal of molecular biology 1999;294(4):829-49.
1999: Ananya Majumdar; A Kettani; Eugene Skripkin; Dinshaw J Patel
Observation of internucleotide NH...N hydrogen bonds in the absence of directly detectable protons.
Journal of biomolecular NMR 1999;15(3):207-11.
1999: AK Suri; B Mao; Shantu Amin; Nicholas E Geacintov; Dinshaw J Patel
Solution conformation of the (+)-trans-anti-benzo[g]chrysene-dA adduct opposite dT in a DNA duplex.
Journal of molecular biology 1999;292(2):289-307.
1999: X Ye; Andrey Gorin; R Frederick; weidong hu; Ananya Majumdar; Weijun Xu; G McLendon; A Ellington; Dinshaw J Patel
RNA architecture dictates the conformations of a bound peptide.
Chemistry & biology 1999;6(9):657-69.
1999: Xiaoling kang; Andrey Gorin; Brian E Hingerty; Suse Broyde; Dinshaw J Patel
Solution structures of aminofluorene [AF]-stacked conformers of the syn [AF]-C8-dG adduct positioned opposite dC or dA at a template-primer junction.
Biochemistry 1999;38(33):10855-70.
1999: Xiaoling kang; Andrey Gorin; R Krishnasamy; Brian E Hingerty; Ashis K Basu; Suse Broyde; Dinshaw J Patel
Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex.
Biochemistry 1999;38(33):10843-54.
1999: B Mao; Xiaoling kang; Andrey Gorin; J Chen; Brian E Hingerty; Shantu Amin; Suse Broyde; Nicholas E Geacintov; Dinshaw J Patel
Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex.
Biochemistry 1999;38(33):10831-42.
1999: L Jiang; Ananya Majumdar; weidong hu; T J Jaishree; Weijun Xu; Dinshaw J Patel
Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer.
Structure (London, England : 1993) 1999;7(7):817-27.
1999: A Kettani; Serge Bouaziz; Eugene Skripkin; Ananya Majumdar; W Wang; RA Jones; Dinshaw J Patel
Interlocked mismatch-aligned arrowhead DNA motifs.
Structure (London, England : 1993) 1999;7(7):803-15.
1999: Dinshaw J Patel
Adaptive recognition in RNA complexes with peptides and protein modules.
Current opinion in structural biology 1999;9(1):74-87.
1998: C H Lin; W Wang; RA Jones; Dinshaw J Patel
Formation of an amino-acid-binding pocket through adaptive zippering-up of a large DNA hairpin loop.
Chemistry & biology 1998;5(10):555-72.
1998: Serge Bouaziz; A Kettani; Dinshaw J Patel
A K cation-induced conformational switch within a loop spanning segment of a DNA quadruplex containing G-G-G-C repeats.
Journal of molecular biology 1998;282(3):637-52.
1998: A Kettani; Serge Bouaziz; Andrey Gorin; H Zhao; RA Jones; Dinshaw J Patel
Solution structure of a Na cation stabilized DNA quadruplex containing G.G.G.G and G.C.G.C tetrads formed by G-G-G-C repeats observed in adeno-associated viral DNA.
Journal of molecular biology 1998;282(3):619-36.
1998: L Jiang; Dinshaw J Patel
Solution structure of the tobramycin-RNA aptamer complex.
Nature structural biology 1998;5(9):769-74.
1998: Dinshaw J Patel; B Mao; Z Gu; Brian E Hingerty; Andrey Gorin; Ashis K Basu; Suse Broyde
Nuclear magnetic resonance solution structures of covalent aromatic amine-DNA adducts and their mutagenic relevance.
Chemical research in toxicology 1998;11(5):391-407.
1998: Z Cai; Andrey Gorin; R Frederick; X Ye; weidong hu; Ananya Majumdar; A Kettani; Dinshaw J Patel
Solution structure of P22 transcriptional antitermination N peptide-boxB RNA complex.
Nature structural biology 1998;5(3):203-12.
1998: B Mao; Brian E Hingerty; Suse Broyde; Dinshaw J Patel
Solution structure of the aminofluorene [AF]-external conformer of the anti-[AF]-C8-dG adduct opposite dC in a DNA duplex.
Biochemistry 1998;37(1):95-106.
1998: B Mao; Brian E Hingerty; Suse Broyde; Dinshaw J Patel
Solution structure of the aminofluorene [AF]-intercalated conformer of the syn-[AF]-C8-dG adduct opposite dC in a DNA duplex.
Biochemistry 1998;37(1):81-94.
1998: Dinshaw J Patel
Molecular insights into the RNA world.
Biopolymers 1998;48(2-3):97-100.
1997: B Mao; Xiaoling kang; Andrey Gorin; Brian E Hingerty; Suse Broyde; Dinshaw J Patel
Solution structure of the aminofluorene-stacked conformer of the syn [AF]-C8-dG adduct positioned at a template-primer junction.
Biochemistry 1997;36(47):14491-501.
1997: B Mao; Andrey Gorin; Xiaoling kang; Brian E Hingerty; Suse Broyde; Dinshaw J Patel
Solution structure of the aminofluorene-intercalated conformer of the syn [AF]-C8-dG adduct opposite a--2 deletion site in the NarI hot spot sequence context.
Biochemistry 1997;36(47):14479-90.
1997: B Feng; Andrey Gorin; Alexander Kolbanovskiy; Brian E Hingerty; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
Biochemistry 1997;36(45):13780-90.
1997: B Feng; Andrey Gorin; Brian E Hingerty; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction.
Biochemistry 1997;36(45):13769-79.
1997: C H Lin; Dinshaw J Patel
Structural basis of DNA folding and recognition in an AMP-DNA aptamer complex: distinct architectures but common recognition motifs for DNA and RNA aptamers complexed to AMP.
Chemistry & biology 1997;4(11):817-32.
1997: Dinshaw J Patel; AK Suri; F Jiang; L Jiang; P Fan; Ajay Royyuru; Sylvie Nonin-Lecomte or Nonin
Structure, recognition and adaptive binding in RNA aptamer complexes.
Journal of molecular biology 1997;272(5):645-64.
1997: Mikael Akke; R Fiala; F Jiang; Dinshaw J Patel; Arthur G Palmer
Base dynamics in a UUCG tetraloop RNA hairpin characterized by 15N spin relaxation: correlations with structure and stability.
RNA (New York, N.Y.) 1997;3(7):702-9.
1997: Dinshaw J Patel
Structural analysis of nucleic acid aptamers.
Current opinion in chemical biology 1997;1(1):32-46.
1997: E Westhof; Dinshaw J Patel
Nucleic acids. From self-assembly to induced-fit recognition.
Current opinion in structural biology 1997;7(3):305-9.
1997: Sylvie Nonin-Lecomte or Nonin; F Jiang; Dinshaw J Patel
Imino proton exchange and base-pair kinetics in the AMP-RNA aptamer complex.
Journal of molecular biology 1997;268(2):359-74.
1997: A Kettani; Serge Bouaziz; W Wang; RA Jones; Dinshaw J Patel
Bombyx mori single repeat telomeric DNA sequence forms a G-quadruplex capped by base triads.
Nature structural biology 1997;4(5):382-9.
1997: Nicholas E Geacintov; Monique Cosman; Brian E Hingerty; Shantu Amin; Suse Broyde; Dinshaw J Patel
NMR solution structures of stereoisometric covalent polycyclic aromatic carcinogen-DNA adduct: principles, patterns, and diversity.
Chemical research in toxicology 1997;10(2):111-46.
1997: Ajay Royyuru; N Ikemoto; Dinshaw J Patel
Solution structure of the calicheamicin gamma 1I-DNA complex.
Journal of molecular biology 1997;265(2):187-201.
1997: Ajay Royyuru; N Ikemoto; Dinshaw J Patel
Solution structure of the esperamicin A1-DNA complex.
Journal of molecular biology 1997;265(2):173-86.
1997: F Jiang; Dinshaw J Patel; X Zhang; H Zhao; R A Jones
Specific labeling approaches to guanine and adenine imino and amino proton assignments in the AMP-RNA aptamer complex.
Journal of biomolecular NMR 1997;9(1):55-62.
1997: L Jiang; AK Suri; R Fiala; Dinshaw J Patel
Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex.
Chemistry & biology 1997;4(1):35-50.
1996: C H Lin; Dinshaw J Patel
Encapsulating an amino acid in a DNA fold.
Nature structural biology 1996;3(12):1046-50.
1996: X Ye; Andrey Gorin; A D Ellington; Dinshaw J Patel
Deep penetration of an alpha-helix into a widened RNA major groove in the HIV-1 rev peptide-RNA aptamer complex.
Nature structural biology 1996;3(12):1026-33.
1996: D Cullinan; A Korobka; Arthur P Grollman; Dinshaw J Patel; M Eisenberg; Carlos de los Santos
NMR solution structure of an oligodeoxynucleotide duplex containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine opposite thymidine: comparison with the duplex containing deoxyadenosine opposite the adduct.
Biochemistry 1996;35(41):13319-27.
1996: A Korobka; D Cullinan; M Cosman; Arthur P Grollman; Dinshaw J Patel; M Eisenberg; Carlos de los Santos
Solution structure of an oligodeoxynucleotide duplex containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine opposite 2'-deoxyadenosine, determined by NMR spectroscopy and restrained molecular dynamics.
Biochemistry 1996;35(41):13310-8.
1996: F Jiang; R Fiala; D Live; Ajay Royyuru; Dinshaw J Patel
RNA folding topology and intermolecular contacts in the AMP-RNA aptamer complex.
Biochemistry 1996;35(40):13250-66.
1996: B Mao; R R Vyas; Brian E Hingerty; Suse Broyde; Ashis K Basu; Dinshaw J Patel
Solution conformation of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dC in a DNA duplex.
Biochemistry 1996;35(39):12659-70.
1996: M Cosman; Brian E Hingerty; N Luneva; Shantu Amin; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Solution conformation of the (-)-cis-anti-benzo[a]pyrenyl-dG adduct opposite dC in a DNA duplex: intercalation of the covalently attached BP ring into the helix with base displacement of the modified deoxyguanosine into the major groove.
Biochemistry 1996;35(30):9850-63.
1996: Y Q Qian; Dinshaw J Patel; F Ulrich Hartl; D J McColl
Nuclear magnetic resonance solution structure of the human Hsp40 (HDJ-1) J-domain.
Journal of molecular biology 1996;260(2):224-35.
1996: F Jiang; Ajay Royyuru; R A Jones; Dinshaw J Patel
Structural basis of RNA folding and recognition in an AMP-RNA aptamer complex.
Nature 1996;382(6587):183-6.
1996: N L Greenbaum; I Radhakrishnan; Dinshaw J Patel; D Hirsh
Solution structure of the donor site of a trans-splicing RNA.
Structure (London, England : 1993) 1996;4(6):725-33.
1996: P Fan; A K Suri; R Fiala; D Live; Dinshaw J Patel
Molecular recognition in the FMN-RNA aptamer complex.
Journal of molecular biology 1996;258(3):480-500.
1996: H Chen; X Liu; Dinshaw J Patel
DNA bending and unwinding associated with actinomycin D antibiotics bound to partially overlapping sites on DNA.
Journal of molecular biology 1996;258(3):457-79.
1995: B Mao; Brian E Hingerty; Suse Broyde; Dinshaw J Patel
Solution conformation of [AF]dG opposite a -2 deletion site in a DNA duplex: intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C8-modified syn guanine and adjacent unpaired 3'-adenine into the major groove.
Biochemistry 1995;34(51):16641-53.
1995: A Kettani; Ajay Royyuru; Dinshaw J Patel
Solution structure of a DNA quadruplex containing the fragile X syndrome triplet repeat.
Journal of molecular biology 1995;254(4):638-56.
1995: X Ye; Ajay Royyuru; Dinshaw J Patel
Molecular recognition in the bovine immunodeficiency virus Tat peptide-TAR RNA complex.
Chemistry & biology 1995;2(12):827-40.
1995: M Cosman; Brian E Hingerty; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Structural alignments of (+)- and (-)-trans-anti-benzo[a]pyrene-dG adducts positioned at a DNA template-primer junction.
Biochemistry 1995;34(46):15334-50.
1995: N Ikemoto; Ajay Royyuru; T T Ling; G A Ellestad; Samuel J Danishefsky; Dinshaw J Patel
Calicheamicin-DNA complexes: warhead alignment and saccharide recognition of the minor groove.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10506-10.
1995: N L Greenbaum; I Radhakrishnan; D Hirsh; Dinshaw J Patel
Determination of the folding topology of the SL1 RNA from Caenorhabditis elegans by multidimensional heteronuclear NMR.
Journal of molecular biology 1995;252(3):314-27.
1995: M Sastry; R Fiala; Dinshaw J Patel
Solution structure of mithramycin dimers bound to partially overlapping sites on DNA.
Journal of molecular biology 1995;251(5):674-89.
1995: Y Wang; Dinshaw J Patel
Solution structure of the Oxytricha telomeric repeat d[G4(T4G4)3] G-tetraplex.
Journal of molecular biology 1995;251(1):76-94.
1995: M Cosman; R Xu; Brian E Hingerty; Shantu Amin; R G Harvey; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Solution conformation of the (-)-trans-anti-5-methylchrysene-dG adduct opposite dC in a DNA duplex: DNA bending associated with wedging of the methyl group of 5-methylchrysene to the 3'-side of the modification site.
Biochemistry 1995;34(18):6247-60.
1995: B Mao; M Cosman; Brian E Hingerty; Suse Broyde; Dinshaw J Patel
Solution conformation of [AF]dG opposite a -1 deletion site in a DNA duplex: intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C8-modified Syn guanine into the major groove.
Biochemistry 1995;34(18):6226-38.
1995: Y Wang; Dinshaw J Patel
Bulge defects in intramolecular pyrimidine.purine.pyrimidine DNA triplexes in solution.
Biochemistry 1995;34(16):5696-704.
1995: C H Lin; Dinshaw J Patel
Solution structure of the covalent duocarmycin A-DNA duplex complex.
Journal of molecular biology 1995;248(1):162-79.
1995: M Sastry; R Fiala; R Lipman; Maria Tomasz; Dinshaw J Patel
Solution structure of the monoalkylated mitomycin C-DNA complex.
Journal of molecular biology 1995;247(2):338-59.
1995: Dinshaw J Patel; B M Gumbiner
Cell-cell recognition. Zipping together a cell adhesion interface.
Nature 1995;374(6520):306-7.
1995: H Chen; Dinshaw J Patel
Solution structure of a quinomycin bisintercalator-DNA complex.
Journal of molecular biology 1995;246(1):164-79.
1995: M Cosman; A Laryea; R Fiala; Brian E Hingerty; Shantu Amin; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Solution conformation of the (-)-trans-anti-benzo[c]phenanthrene-dA ([BPh]dA) adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrenyl ring to the 3'-side of the adduct site and comparison with the (+)-trans-anti-[BPh]dA opposite dT stereoisomer.
Biochemistry 1995;34(4):1295-307.
1994: Y Wang; Dinshaw J Patel
Solution structure of the Tetrahymena telomeric repeat d(T2G4)4 G-tetraplex.
Structure (London, England : 1993) 1994;2(12):1141-56.
1994: Y Wang; Dinshaw J Patel
Solution structure of the d(T-C-G-A) duplex at acidic pH. A parallel-stranded helix containing C+ .C, G.G and A.A pairs.
Journal of molecular biology 1994;242(4):508-26.
1994: M Cosman; R Fiala; Brian E Hingerty; Shantu Amin; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Solution conformation of the (+)-cis-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
Biochemistry 1994;33(38):11518-27.
1994: M Cosman; R Fiala; Brian E Hingerty; Shantu Amin; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Solution conformation of the (+)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the major groove.
Biochemistry 1994;33(38):11507-17.
1994: I Radhakrishnan; Dinshaw J Patel
DNA triplexes: solution structures, hydration sites, energetics, interactions, and function.
Biochemistry 1994;33(38):11405-16.
1994: I Radhakrishnan; Dinshaw J Patel
Solution structure and hydration patterns of a pyrimidine.purine.pyrimidine DNA triplex containing a novel T.CG base-triple.
Journal of molecular biology 1994;241(4):600-19.
1994: Dinshaw J Patel
Glycoprotein hormones. A clasped embrace.
Nature 1994;369(6480):438-9.
1994: I Radhakrishnan; Dinshaw J Patel
Hydration sites in purine.purine.pyrimidine and pyrimidine.purine.pyrimidine DNA triplexes in aqueous solution.
Structure (London, England : 1993) 1994;2(5):395-405.
1994: Dinshaw J Patel
Protein-nucleic-acid interaction. A molecular handshake.
Nature 1994;367(6465):688-90.
1994: I Radhakrishnan; Dinshaw J Patel
Solution structure of a pyrimidine.purine.pyrimidine DNA triplex containing T.AT, C+.GC and G.TA triples.
Structure (London, England : 1993) 1994;2(1):17-32.
1993: Y Wang; Dinshaw J Patel
Solution structure of a parallel-stranded G-quadruplex DNA.
Journal of molecular biology 1993;234(4):1171-83.
1993: Y Wang; Dinshaw J Patel
Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex.
Structure (London, England : 1993) 1993;1(4):263-82.
1993: M Cosman; R Fiala; Brian E Hingerty; A Laryea; H Lee; R G Harvey; Shantu Amin; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Solution conformation of the (+)-trans-anti-[BPh]dA adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrene to the 5'-side of the adduct site without disruption of the modified base pair.
Biochemistry 1993;32(46):12488-97.
1993: I Radhakrishnan; Carlos de los Santos; Dinshaw J Patel
Nuclear magnetic resonance structural studies of A.AT base triple alignments in intramolecular purine.purine.pyrimidine DNA triplexes in solution.
Journal of molecular biology 1993;234(1):188-97.
1993: I Radhakrishnan; Dinshaw J Patel; E S Priestly; H M Nash; P B Dervan
NMR structural studies on a nonnatural deoxyribonucleoside which mediates recognition of GC base pairs in pyrimidine-purine-pyrimidine DNA triplexes.
Biochemistry 1993;32(41):11228-34.
1993: I Radhakrishnan; Dinshaw J Patel
Solution structure of a purine.purine.pyrimidine DNA triplex containing G.GC and T.AT triples.
Structure (London, England : 1993) 1993;1(2):135-52.
1993: Dinshaw J Patel
Nucleic acid recognition. Marriage of convenience.
Nature 1993;365(6446):490-2.
1993: M Sastry; Dinshaw J Patel
Solution structure of the mithramycin dimer-DNA complex.
Biochemistry 1993;32(26):6588-604.
1993: M A Rosen; Dinshaw J Patel
Structural features of a three-stranded DNA junction containing a C-C junctional bulge.
Biochemistry 1993;32(26):6576-87.
1993: M A Rosen; Dinshaw J Patel
Conformational differences between bulged pyrimidines (C-C) and purines (A-A, I-I) at the branch point of three-stranded DNA junctions.
Biochemistry 1993;32(26):6563-75.
1993: Dinshaw J Patel
Nucleic acid architecture. Tetrads through interdigitation.
Nature 1993;363(6429):499-500.
1993: M Cosman; Carlos de los Santos; R Fiala; Brian E Hingerty; V Ibanez; E Luna; R Harvey; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine.
Biochemistry 1993;32(16):4145-55.
1993: P Huang; Dinshaw J Patel; M Eisenberg
Solution structure of the exocyclic 1,N2-propanodeoxyguanosine adduct opposite deoxyadenosine in a DNA nonamer duplex at pH 8.9. model of pH-dependent conformational transition.
Biochemistry 1993;32(15):3852-66.
1993: L P van Houte; C J van Garderen; Dinshaw J Patel
The antitumor drug nogalamycin forms two different intercalation complexes with d(GCGT).d(ACGC).
Biochemistry 1993;32(6):1667-74.
1992: S Gopalakrishnan; X Liu; Dinshaw J Patel
Solution structure of the covalent sterigmatocystin-DNA adduct.
Biochemistry 1992;31(44):10790-801.
1992: Y Wang; Dinshaw J Patel
Guanine residues in d(T2AG3) and d(T2G4) form parallel-stranded potassium cation stabilized G-quadruplexes with anti glycosidic torsion angles in solution.
Biochemistry 1992;31(35):8112-9.
1992: Carlos de los Santos; M Cosman; Brian E Hingerty; V Ibanez; L A Margulis; Nicholas E Geacintov; Suse Broyde; Dinshaw J Patel
Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer.
Biochemistry 1992;31(23):5245-52.
1992: M A Rosen; L Shapiro; Dinshaw J Patel
Solution structure of a trinucleotide A-T-A bulge loop within a DNA duplex.
Biochemistry 1992;31(16):4015-26.
1992: M A Rosen; D Live; Dinshaw J Patel
Comparative NMR study of A(n)-bulge loops in DNA duplexes: intrahelical stacking of A, A-A, and A-A-A bulge loops.
Biochemistry 1992;31(16):4004-14.
1992: I Radhakrishnan; Dinshaw J Patel; X Gao
Three-dimensional homonuclear NOESY-TOCSY of an intramolecular pyrimidine.purine.pyrimidine DNA triplex containing a central G.TA triple: nonexchangeable proton assignments and structural implications.
Biochemistry 1992;31(9):2514-23.
1992: JL Leroy; X L Gao; Vinod K Misra; Maurice Guéron; Dinshaw J Patel
Proton exchange in DNA-luzopeptin and DNA-echinomycin bisintercalation complexes: rates and processes of base-pair opening.
Biochemistry 1992;31(5):1407-15.
1992: X L Gao; P Mirau; Dinshaw J Patel
Structure refinement of the chromomycin dimer-DNA oligomer complex in solution.
Journal of molecular biology 1992;223(1):259-79.
1991: Y Wang; Carlos de los Santos; X O Gao; K Greene; D Live; Dinshaw J Patel
Multinuclear nuclear magnetic resonance studies of Na cation-stabilized complex formed by d(G-G-T-T-T-T-C-G-G) in solution. Implications for G-tetrad structures.
Journal of molecular biology 1991;222(3):819-32.
1991: X Liu; H Chen; Dinshaw J Patel
Solution structure of actinomycin-DNA complexes: drug intercalation at isolated G-C sites.
Journal of biomolecular NMR 1991;1(4):323-47.
1991: I Radhakrishnan; Carlos de los Santos; Dinshaw J Patel
Nuclear magnetic resonance structural studies of intramolecular purine.purine.pyrimidine DNA triplexes in solution. Base triple pairing alignments and strand direction.
Journal of molecular biology 1991;221(4):1403-18.
1991: I Radhakrishnan; X Gao; Carlos de los Santos; D Live; Dinshaw J Patel
NMR structural studies of intramolecular (Y+)n.(R+)n(Y-)nDNA triplexes in solution: imino and amino proton and nitrogen markers of G.TA base triple formation.
Biochemistry 1991;30(37):9022-30.
1991: M G Zagorski; David G Norman; C J Barrow; T Iwashita; K Tachibana; Dinshaw J Patel
Solution structure of pardaxin P-2.
Biochemistry 1991;30(32):8009-17.
1991: JL Leroy; X L Gao; Maurice Guéron; Dinshaw J Patel
Proton exchange and internal motions in two chromomycin dimer-DNA oligomer complexes.
Biochemistry 1991;30(23):5653-61.
1991: X L Zhang; Dinshaw J Patel
Solution structure of the luzopeptin-DNA complex.
Biochemistry 1991;30(16):4026-41.
1991: M Kouchakdjian; M Eisenberg; Francis Johnson; Arthur P Grollman; Dinshaw J Patel
Structural features of an exocyclic adduct positioned opposite an abasic site in a DNA duplex.
Biochemistry 1991;30(13):3262-70.
1991: Carlos de los Santos; M Kouchakdjian; K Yarema; A Basu; John M Essigmann; Dinshaw J Patel
NMR studies of the exocyclic 1,N6-ethenodeoxyadenosine adduct (epsilon dA) opposite deoxyguanosine in a DNA duplex. Epsilon dA(syn).dG(anti) pairing at the lesion site.
Biochemistry 1991;30(7):1828-35.
1991: M Kouchakdjian; M Eisenberg; K Yarema; A Basu; John M Essigmann; Dinshaw J Patel
NMR studies of the exocyclic 1,N6-ethenodeoxyadenosine adduct (epsilon dA) opposite thymidine in a DNA duplex. Nonplanar alignment of epsilon dA(anti) and dT(anti) at the lesion site.
Biochemistry 1991;30(7):1820-8.
1991: M Kouchakdjian; V Bodepudi; Shinya Shibutani; M Eisenberg; Francis Johnson; Arthur P Grollman; Dinshaw J Patel
NMR structural studies of the ionizing radiation adduct 7-hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) opposite deoxyadenosine in a DNA duplex. 8-Oxo-7H-dG(syn).dA(anti) alignment at lesion site.
Biochemistry 1991;30(5):1403-12.
1991: J Ashcroft; D H Live; Dinshaw J Patel; David Cowburn
Heteronuclear two-dimensional 15N- and 13C-NMR studies of DNA oligomers and their netropsin complexes using indirect proton detection.
Biopolymers 1991;31(1):45-55.
1990: X L Gao; Dinshaw J Patel
Chromomycin dimer-DNA oligomer complexes. Sequence selectivity and divalent cation specificity.
Biochemistry 1990;29(49):10940-56.
1990: X L Zhang; Dinshaw J Patel
Solution structure of the nogalamycin-DNA complex.
Biochemistry 1990;29(40):9451-66.
1990: M Kouchakdjian; M Eisenberg; D Live; E Marinelli; Arthur P Grollman; Dinshaw J Patel
NMR studies of an exocyclic 1,N2-propanodeoxyguanosine adduct (X) located opposite deoxyadenosine (A) in DNA duplexes at basic pH: simultaneous partial intercalation of X and A between stacked bases.
Biochemistry 1990;29(18):4456-65.
1990: David G Norman; D Live; M Sastry; R Lipman; Brian E Hingerty; Maria Tomasz; Suse Broyde; Dinshaw J Patel
NMR and computational characterization of mitomycin cross-linked to adjacent deoxyguanosines in the minor groove of the d(T-A-C-G-T-A).d(T-A-C-G-T-A) duplex.
Biochemistry 1990;29(11):2861-75.
1990: M W Kalnik; David G Norman; B F Li; PF Swann; Dinshaw J Patel
Conformational transitions in thymidine bulge-containing deoxytridecanucleotide duplexes. Role of flanking sequence and temperature in modulating the equilibrium between looped out and stacked thymidine bulge states.
The Journal of biological chemistry 1990;265(2):636-47.
1989: M G Zagorski; J U Bowie; A K Vershon; Robert T Sauer; Dinshaw J Patel
NMR studies of Arc repressor mutants: proton assignments, secondary structure, and long-range contacts for the thermostable proline-8----leucine variant of Arc.
Biochemistry 1989;28(25):9813-25.
1989: M C Wilkinson; Philip Potter; L Cawkwell; P Georgiadis; Dinshaw J Patel; PF Swann; Geoffrey P Margison
Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides.
Nucleic acids research 1989;17(21):8475-84.
1989: David G Norman; P Abuaf; Brian E Hingerty; D Live; D Grunberger; Suse Broyde; Dinshaw J Patel
NMR and computational characterization of the N-(deoxyguanosin-8-yl)aminofluorene adduct [(AF)G] opposite adenosine in DNA: (AF)G[syn].A[anti] pair formation and its pH dependence.
Biochemistry 1989;28(18):7462-76.
1989: Carlos de los Santos; M Rosen; Dinshaw J Patel
NMR studies of DNA (R+)n.(Y-)n.(Y+)n triple helices in solution: imino and amino proton markers of T.A.T and C.G.C+ base-triple formation.
Biochemistry 1989;28(18):7282-9.
1989: M W Kalnik; B F Li; PF Swann; Dinshaw J Patel
O6-ethylguanine carcinogenic lesions in DNA: an NMR study of O6etG.C pairing in dodecanucleotide duplexes.
Biochemistry 1989;28(15):6182-92.
1989: M W Kalnik; B F Li; PF Swann; Dinshaw J Patel
O6-ethylguanine carcinogenic lesions in DNA: an NMR study of O6etG.T pairing in dodecanucleotide duplexes.
Biochemistry 1989;28(15):6170-81.
1989: M Kouchakdjian; E Marinelli; X L Gao; Francis Johnson; Arthur P Grollman; Dinshaw J Patel
NMR studies of exocyclic 1,N2-propanodeoxyguanosine adducts (X) opposite purines in DNA duplexes: protonated X(syn).A(anti) pairing (acidic pH) and X(syn).G(anti) pairing (neutral pH) at the lesion site.
Biochemistry 1989;28(13):5647-57.
1989: X L Gao; Dinshaw J Patel
Antitumour drug-DNA interactions: NMR studies of echinomycin and chromomycin complexes.
Quarterly reviews of biophysics 1989;22(2):93-138.
1989: M W Kalnik; C N Chang; Francis Johnson; Arthur P Grollman; Dinshaw J Patel
NMR studies of abasic sites in DNA duplexes: deoxyadenosine stacks into the helix opposite acyclic lesions.
Biochemistry 1989;28(8):3373-83.
1989: M W Kalnik; David G Norman; PF Swann; Dinshaw J Patel
Conformation of adenosine bulge-containing deoxytridecanucleotide duplexes in solution. Extra adenosine stacks into duplex independent of flanking sequence and temperature.
The Journal of biological chemistry 1989;264(7):3702-12.
1989: X L Gao; Dinshaw J Patel
Solution structure of the chromomycin-DNA complex.
Biochemistry 1989;28(2):751-62.
1989: M W Kalnik; David G Norman; M G Zagorski; PF Swann; Dinshaw J Patel
Conformational transitions in cytidine bulge-containing deoxytridecanucleotide duplexes: extra cytidine equilibrates between looped out (low temperature) and stacked (elevated temperature) conformations in solution.
Biochemistry 1989;28(1):294-303.
1988: M Kouchakdjian; B F Li; PF Swann; Dinshaw J Patel
Pyrimidine.pyrimidine base-pair mismatches in DNA. A nuclear magnetic resonance study of T.T pairing at neutral pH and C.C pairing at acidic pH in dodecanucleotide duplexes.
Journal of molecular biology 1988;202(1):139-55.
1988: X L Gao; Dinshaw J Patel
NMR studies of echinomycin bisintercalation complexes with d(A1-C2-G3-T4) and d(T1-C2-G3-A4) duplexes in aqueous solution: sequence-dependent formation of Hoogsteen A1.T4 and Watson--Crick T1.A4 base pairs flanking the bisintercalation site.
Biochemistry 1988;27(5):1744-51.
1988: M W Kalnik; C N Chang; Arthur P Grollman; Dinshaw J Patel
NMR studies of abasic sites in DNA duplexes: deoxyadenosine stacks into the helix opposite the cyclic analogue of 2-deoxyribose.
Biochemistry 1988;27(3):924-31.
1988: M W Kalnik; M Kouchakdjian; B F Li; PF Swann; Dinshaw J Patel
Base pair mismatches and carcinogen-modified bases in DNA: an NMR study of G.T and G.O4meT pairing in dodecanucleotide duplexes.
Biochemistry 1988;27(1):108-15.
1988: M W Kalnik; M Kouchakdjian; B F Li; PF Swann; Dinshaw J Patel
Base pair mismatches and carcinogen-modified bases in DNA: an NMR study of A.C and A.O4meT pairing in dodecanucleotide duplexes.
Biochemistry 1988;27(1):100-8.
1987: X L Gao; Dinshaw J Patel
NMR studies of A.C mismatches in DNA dodecanucleotides at acidic pH. Wobble A(anti).C(anti) pair formation.
The Journal of biological chemistry 1987;262(35):16973-84.
1987: Dinshaw J Patel; L Shapiro; D Hare
DNA and RNA: NMR studies of conformations and dynamics in solution.
Quarterly reviews of biophysics 1987;20(1-2):35-112.
1987: B F Li; PF Swann; M Kalnik; Dinshaw J Patel
Synthesis and structural studies by nuclear magnetic resonance of dodecadeoxynucleotides containing O6-methylguanine, O6-ethylguanine and O4-methylthymine.
IARC scientific publications 1987;(84):44-8.
1987: Dinshaw J Patel; L Shapiro; D Hare
Nuclear magnetic resonance and distance geometry studies of DNA structures in solution.
Annual review of biophysics and biophysical chemistry 1987;16():423-54.
1986: D Hare; L Shapiro; Dinshaw J Patel
Extrahelical adenosine stacks into right-handed DNA: solution conformation of the d(C-G-C-A-G-A-G-C-T-C-G-C-G) duplex deduced from distance geometry analysis of nuclear Overhauser effect spectra.
Biochemistry 1986;25(23):7456-64.
1986: D Hare; L Shapiro; Dinshaw J Patel
Wobble dG X dT pairing in right-handed DNA: solution conformation of the d(C-G-T-G-A-A-T-T-C-G-C-G) duplex deduced from distance geometry analysis of nuclear Overhauser effect spectra.
Biochemistry 1986;25(23):7445-56.
1986: Dinshaw J Patel; L Shapiro; S A Kozlowski; B L Gaffney; R A Jones
Covalent carcinogenic O6-methylguanosine lesions in DNA. Structural studies of the O6 meG X A and O6meG X G interactions in dodecanucleotide duplexes.
Journal of molecular biology 1986;188(4):677-92.
1986: Dinshaw J Patel; L Shapiro; D Hare
Sequence-dependent conformations of DNA duplexes: the TATA segment of the d(G-G-T-A-T-A-C-C) duplex in aqueous solution.
Biopolymers 1986;25(4):693-706.
1986: Dinshaw J Patel; L Shapiro
Sequence-dependent recognition of DNA duplexes: netropsin complexation to the TATA site of the d(G-G-T-A-T-A-C-C) duplex in aqueous solution.
Biopolymers 1986;25(4):707-27.
1986: Dinshaw J Patel; L Shapiro; S A Kozlowski; B L Gaffney; R A Jones
Structural studies of the O6meG.T interaction in the d(C-G-T-G-A-A-T-T-C-O6meG-C-G) duplex.
Biochemistry 1986;25(5):1036-42.
1986: Dinshaw J Patel; L Shapiro; S A Kozlowski; B L Gaffney; R A Jones
Structural studies of the O6meG.C interaction in the d(C-G-C-G-A-A-T-T-C-O6meG-C-G) duplex.
Biochemistry 1986;25(5):1027-36.
1986: Dinshaw J Patel; L Shapiro; D Hare
Sequence-dependent conformation of DNA duplexes. The AATT segment of the d(G-G-A-A-T-T-C-C) duplex in aqueous solution.
The Journal of biological chemistry 1986;261(3):1223-9.
1986: Dinshaw J Patel; L Shapiro
Sequence-dependent recognition of DNA duplexes. Netropsin complexation to the AATT site of the d(G-G-A-A-T-T-C-C) duplex in aqueous solution.
The Journal of biological chemistry 1986;261(3):1230-40.
1985: Dinshaw J Patel; L Shapiro; S A Kozlowski; B L Gaffney; S Kuzmich; R A Jones
Covalent carcinogenic lesions in DNA: NMR studies of O6-methylguanosine containing oligonucleotide duplexes.
Biochimie 1985;67(7-8):861-86.
1985: Dinshaw J Patel; L Shapiro
Molecular recognition in noncovalent antitumor agent-DNA complexes: NMR studies of the base and sequence dependent recognition of the DNA minor groove by netropsin.
Biochimie 1985;67(7-8):887-915.
1985: Dinshaw J Patel; S A Kozlowski; M Weiss; R Bhatt
Conformation and dynamics of the Pribnow box region of the self-complementary d(C-G-A-T-T-A-T-A-A-T-C-G) duplex in solution.
Biochemistry 1985;24(4):936-44.
1985: Dinshaw J Patel; S A Kozlowski; D R Hare; B Reid; S Ikuta; N Lander; K Itakura
Conformation, dynamics, and structural transitions of the TATA box region of self-complementary d[(C-G)n-T-A-T-A-(C-G)n] duplexes in solution.
Biochemistry 1985;24(4):926-35.
1984: M A Weiss; R T Sauer; Dinshaw J Patel; M Karplus
Amino-terminal arm of the lambda repressor: a 1H NMR study.
Biochemistry 1984;23(22):5090-5.
1984: Dinshaw J Patel; S A Kozlowski; S Ikuta; K Itakura
Dynamics of DNA duplexes containing internal G.T, G.A, A.C, and T.C pairs: hydrogen exchange at and adjacent to mismatch sites.
Federation proceedings 1984;43(11):2663-70.
1984: Dinshaw J Patel; S A Kozlowski; S Ikuta; K Itakura
Deoxyguanosine-deoxyadenosine pairing in the d(C-G-A-G-A-A-T-T-C-G-C-G) duplex: conformation and dynamics at and adjacent to the dG X dA mismatch site.
Biochemistry 1984;23(14):3207-17.
1984: Dinshaw J Patel; S A Kozlowski; S Ikuta; K Itakura
Deoxyadenosine-deoxycytidine pairing in the d(C-G-C-G-A-A-T-T-C-A-C-G) duplex: conformation and dynamics at and adjacent to the dA X dC mismatch site.
Biochemistry 1984;23(14):3218-26.
1984: M A Weiss; Dinshaw J Patel; R T Sauer; M Karplus
1H-NMR study of the lambda operator site OL1: assignment of the imino and adenine H2 resonances.
Nucleic acids research 1984;12(9):4035-47.
1984: A Möller; A Nordheim; S A Kozlowski; Dinshaw J Patel; A Rich
Bromination stabilizes poly(dG-dC) in the Z-DNA form under low-salt conditions.
Biochemistry 1984;23(1):54-62.
1984: M A Weiss; Dinshaw J Patel; R T Sauer; M Karplus
Two-dimensional 1H NMR study of the lambda operator site OL1: a sequential assignment strategy and its application.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(1):130-4.
1983: M A Weiss; M Karplus; Dinshaw J Patel; R T Sauer
Solution NMR studies of intact lambda repressor.
Journal of biomolecular structure & dynamics 1983;1(1):151-7.
1983: Dinshaw J Patel; S A Kozlowski; R Bhatt
Sequence dependence of base-pair stacking in right-handed DNA in solution: proton nuclear Overhauser effect NMR measurements.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(13):3908-12.
1983: Dinshaw J Patel; S Ikuta; S Kozlowski; K Itakura
Sequence dependence of hydrogen exchange kinetics in DNA duplexes at the individual base pair level in solution.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(8):2184-8.
1983: A Pardi; K M Morden; Dinshaw J Patel; Ignacio Tinoco
Kinetics for exchange of the imino protons of the d(C-G-C-G-A-A-T-T-C-G-C-G) double helix in complexes with the antibiotics netropsin and/or actinomycin.
Biochemistry 1983;22(5):1107-13.
1983: Dinshaw J Patel; S A Kozlowski; S Ikuta; K Itakura; R Bhatt; D R Hare
NMR studies of DNA conformation and dynamics in solution.
Cold Spring Harbor symposia on quantitative biology 1983;47 Pt 1():197-206.
1982: A Pardi; K M Morden; Dinshaw J Patel; Ignacio Tinoco
Kinetics for exchange of imino protons in the d(C-G-C-G-A-A-T-T-C-G-C-G) double helix and in two similar helices that contain a G . T base pair, d(C-G-T-G-A-A-T-T-C-G-C-G), and an extra adenine, d(C-G-C-A-G-A-A-T-T-C-G-C-G).
Biochemistry 1982;21(25):6567-74.
1982: Dinshaw J Patel
Antibiotic-DNA interactions: intermolecular nuclear Overhauser effects in the netropsin-d(C-G-C-G-A-A-T-T-C-G-C-G) complex in solution.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(21):6424-8.
1982: Dinshaw J Patel; A Pardi; K Itakura
DNA conformation, dynamics, and interactions in solution.
Science (New York, N.Y.) 1982;216(4546):581-90.
1982: Dinshaw J Patel; S A Kozlowski; A Nordheim; A Rich
Right-handed and left-handed DNA: studies of B- and Z-DNA by using proton nuclear Overhauser effect and P NMR.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(5):1413-7.
1982: Dinshaw J Patel; S A Kozlowski; L A Marky; J A Rice; C Broka; K Itakura; K J Breslauer
Structure and energetics of a hexanucleotide duplex with stacked trinucleotide ends formed by the sequence d(GAATTCGCG).
Biochemistry 1982;21(3):451-5.
1982: Dinshaw J Patel; S A Kozlowski; L A Marky; J A Rice; C Broka; K Itakura; K J Breslauer
Extra adenosine stacks into the self-complementary d(CGCAGAATTCGCG) duplex in solution.
Biochemistry 1982;21(3):445-51.
1982: Dinshaw J Patel; S A Kozlowski; L A Marky; J A Rice; C Broka; J Dallas; K Itakura; K J Breslauer
Structure, dynamics, and energetics of deoxyguanosine . thymidine wobble base pair formation in the self-complementary d(CGTGAATTCGCG) duplex in solution.
Biochemistry 1982;21(3):437-44.
1982: Dinshaw J Patel; S A Kozlowski; L A Marky; C Broka; J A Rice; K Itakura; K J Breslauer
Premelting and melting transitions in the d(CGCGAATTCGCG) self-complementary duplex in solution.
Biochemistry 1982;21(3):428-36.
1981: Dinshaw J Patel; S A Kozlowski; J A Rice; C Broka; K Itakura
Mutual interaction between adjacent dG . dC actinomycin binding sites and dA . dT netropsin binding sites on the self-complementary d(C-G-C-G-A-A-T-T-C-G-C-G) duplex in solution.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(12):7281-4.
1981: Dinshaw J Patel; S A Kozlowski; J W Suggs; S D Cox
Right-handed alternating DNA conformation: poly(dA-dT) adopts the same dinucleotide repeat with cesium, tetraalkylammonium, and 3 alpha, 5 beta, 17 beta-dipyrrolidinium steroid dimethiodide cations in aqueous solution.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(7):4063-7.
1981: Dinshaw J Patel; S A Kozlowski; J A Rice
Hydrogen bonding, overlap geometry, and sequence specificity in anthracycline antitumor antibiotic.DNA complexes in solution.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(6):3333-7.
1981: L A Marky; Dinshaw J Patel; K J Breslauer
Effect of tetramethylammonium ion on the helix-to-coil transition of poly(deoxyadenylylthymidine): a nuclear magnetic resonance and calorimetric investigation.
Biochemistry 1981;20(6):1427-31.
1981: Dinshaw J Patel; E J Gabbay
Nitroaniline diamine.poly(dA-dT) complexes: 1H and 19F NMR parameters for full intercalation of aromatic rings into DNA.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(3):1351-5.
1980: D M Chen; T T Sakai; Jerry D Glickson; Dinshaw J Patel
Bleomycin-A2 complexes with poly(dA--dT): a proton nuclear magnetic resonance study of the nonexchangeable hydrogens.
Biochemical and biophysical research communications 1980;92(1):197-205.
1979: Dinshaw J Patel
Netropsin . dG-dG-dA-dA-dT-dT-dC-dC complex. Antibiotic binding at adenine . thymine base pairs in the minor groove of the self-complementary octanucleotide duplex.
European journal of biochemistry / FEBS 1979;99(2):369-78.
1979: Dinshaw J Patel; L L Canuel; F M Pohl
"Alternating B-DNA" conformation for the oligo(dG-dC) duplex in high-salt solution.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(6):2508-11.
1979: Dinshaw J Patel; L L Canuel
Helix-coil transition of the self-complementary dG-dG-dA-dA-dT-dT-dC-dC duplex.
European journal of biochemistry / FEBS 1979;96(2):267-76.
1979: Dinshaw J Patel
Helix-coil transition of the dG-dC-dG-dC self-complementary duplex and complex formation with daunomycin in solution.
Biopolymers 1979;18(3):553-69.
1979: Dinshaw J Patel; L L Canuel
Steroid diamine-nucleic acid interactions: partial insertion of dipyrandium between unstacked base pairs of the poly(dA-dT) duplex in solution.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(1):24-8.
1978: Dinshaw J Patel; L L Canuel
Anthracycline antitumor antibiotic nucleic-acid interactions. Structural aspects of the daunomycin poly(dA-dT) complex in solution.
European journal of biochemistry / FEBS 1978;90(2):247-54.
1978: Dinshaw J Patel; C Shen
Sugar pucker geometries at the intercalation site of propidium diiodide into miniature RNA and DNA duplexes in solution.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(6):2553-7.
1978: Dinshaw J Patel
Synthetic RNA and DNA duplexes. Premelting, melting and postmelting transitions of alternating inosine-cytosine polynucleotides in solution.
European journal of biochemistry / FEBS 1978;83(2):453-64.
1977: Dinshaw J Patel
Mutagen-nucleic acid complexes at the polynucleotide duplex level in solution: intercalation of proflavine into poly(dA-dT) and the melting transition of the complex.
Biopolymers 1977;16(12):2739-54.
1977: Dinshaw J Patel; L L Canuel
Netropsin-poly(dA-dT) complex in solution: structure and dynamics of antibiotic-free base pair regions and those centered on bound netropsin.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(12):5207-11.
1977: Dinshaw J Patel
d-CpCpGpG and d-GpGpCpC self-complementary duplexes: Nmr studies of the helix-coil transition.
Biopolymers 1977;16(8):1635-56.
1977: Dinshaw J Patel; L L Canuel
Sequence specificity of mutagen-nucleic acid complexes in solution: intercalation and mutagen-base pair overlap geometries for proflavine binding to dC-dC-dG-dG and dG-dG-dC-dC self-complementary duplexes.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(7):2624-8.
1977: Dinshaw J Patel; L L Canuel
Biphasic helix-coil transition of the ethidium bromide-poly (dA-dT) and the propidium diiodide - poly (dA-dT) complexes. Stabilization of base-pair regions centered about the intercalation site.
Biopolymers 1977;16(4):857-73.
1976: C Shen; Dinshaw J Patel
Free acid, anion, alkali, and alkaline earth complexes of lasalocid a (X537A) in methanol: structural and kinetic studies at the monomer level.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(12):4277-81.
1976: Dinshaw J Patel; L L Canuel
Ethidium bromide-(dC-dG-dC-dG)2 complex in solution: intercalation and sequence specificity of drug binding at the tetranucleotide duplex level.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(10):3343-7.
1976: Dinshaw J Patel
NMR studies of the structure and stability of the 1 : 2 actinomycin D-d-pG-C complex in aqueous solution.
Biochimica et biophysica acta 1976;442(1):98-108.
1976: Dinshaw J Patel; A E Tonelli
N-methylleucine gramicidin-S and (di-N-methylleucine) gramicidin-S conformations with cis L-Orn-L-N-MeLeu peptide bonds.
Biopolymers 1976;15(8):1623-35.
1976: Dinshaw J Patel; C Shen
Structural and kinetic studies of lasalocid A (X537A) and its silver, sodium, and barium salts in nonpolar solvents.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(6):1786-90.
1976: Dinshaw J Patel; L L Canuel
Nuclear magnetic resonance studies of slowly exchanging peptide protons in cytochrome c in aqueous solution.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(5):1398-402.
1976: Dinshaw J Patel
Proton and phosphorus NMR studies of d-CpG(pCpG)n duplexes in solution. Helix-coil transition and complex formation with actinomycin-D.
Biopolymers 1976;15(3):533-58.
1976: Dinshaw J Patel; L Canuel
Nuclear magnetic resonance studies of the helix-coil transition of poly (dA-dT) in aqueous solution.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(3):674-8.
1976: K Nakanishi; A P Yudd; R K Crouch; G L Olson; H C Cheung; R Govindjee; T G Ebrey; Dinshaw J Patel
Letter: Allenic retinals and visual pigment analogues.
Journal of the American Chemical Society 1976;98(1):236-8.
1975: Dinshaw J Patel; L L Canuel; F A Bovey; C Woodward
Assignment of the imidazole ring nitrogen protons of histidine 48 in the proton NMR spectrum of ribonuclease A in water solution.
Biochimica et biophysica acta 1975;400(2):275-82.
1975: C W Hilbers; Dinshaw J Patel
Proton nuclear magnetic resonance investigations of the nucleation and propagation reactions associated with the helix-coil transition of d-ApTpGpCpApT in H2O solution.
Biochemistry 1975;14(12):2656-60.
1975: Dinshaw J Patel; C W Hilbers
Proton nuclear magnetic resonance investigations of fraying in double-stranded d-ApTpGpCpApT in H2O solution.
Biochemistry 1975;14(12):2651-6.
1975: Dinshaw J Patel; L L Canuel; F A Bovey
Reassignment of the active site histidines in ribonuclease A by selective deuteration studies.
Biopolymers 1975;14(5):987-97.
1975: Dinshaw J Patel; C Woodward; L L Canuel; F A Bovey
Correlation of exchangeable (NH) and nonexchangeable (C2H) histidine resonances in the proton NMR spectrum of ribonuclease A in aqueous solution.
Biopolymers 1975;14(5):975-86.
1975: Dinshaw J Patel; L L Canuel; C Woodward; F A Bovey
Assignment of the histidine 12-threonine 45 hydrogen-bonded proton in the NMR spectrum of ribonuclease A in H2O.
Biopolymers 1975;14(5):959-74.
1975: Dinshaw J Patel
The predicted secondary structure of the N-terminal sequence of the lac repressor and proposed models for its complexation to the lac operator.
Biochemistry 1975;14(5):1057-9.
1974: Dinshaw J Patel
Peptide antibiotic-oligonucleotide interactions. Nuclear magnetic resonance investigations of complex formation between actinomycin D and d-ApTpGpCpApT in aqueous solution.
Biochemistry 1974;13(11):2396-402.
1974: Dinshaw J Patel
Peptide antibiotic-dinucleotide interactions. Nuclear magnetic resonance investigations of complex formation between actinomycin D and d-pGpC in aqueous solution.
Biochemistry 1974;13(11):2388-95.
1974: S Ogawa; Dinshaw J Patel; S R Simon
Proton magnetic resonance study of the switch between the two quaternary structures in high-affinity hemoglobins in the deoxy state.
Biochemistry 1974;13(10):2001-6.
1974: Dinshaw J Patel; A E Tonelli
Proton nuclear magnetic resonance investigations and ring current calculations of guanine N-1 and thymine N-3 hydrogen-bonded protons in double-helical deoxyribonucleotides in aqueous solution.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(5):1945-8.
1974: Dinshaw J Patel
Peptide antibiotic-nucleotide interactions. Nuclear magnetic resonance investigations of complex formation between actinomycin d and deoxyguanosine 5'-monophosphate in aqueous solution.
Biochemistry 1974;13(7):1476-82.
1974: Dinshaw J Patel; A E Tonelli
A comparison of the solution and crystal conformations for the alkali metal ion complex of antamanide.
Biochemistry 1974;13(4):788-92.
1974: Dinshaw J Patel; A E Tonelli
Assignment of the proton Nmr chemical shifts of the T-N3H and G-N1H proton resonances in isolated AT and GC Watson-Crick base pairs in double-stranded deoxy oligonucleotides in aqueous solution.
Biopolymers 1974;13(10):1943-64.
1973: Dinshaw J Patel; A E Tonelli; P Pfaender; H Faulstich; T Wieland
Experimental and calculated conformational characteristics of the bicyclic heptapeptide phalloidin.
Journal of molecular biology 1973;79(1):185-96.
1973: Dinshaw J Patel
Conformation of antamanide-sodium in solution.
Biochemistry 1973;12(4):677-88.
1973: Dinshaw J Patel
Antamanide conformations in nonaqueous media. Dependence on hydrogen-bond acceptor properties of solvent.
Biochemistry 1973;12(4):667-76.
1973: Dinshaw J Patel
Carbon framework of valinomycin and its metal ion complex in solution.
Biochemistry 1973;12(3):496-501.
1973: Dinshaw J Patel; A E Tonelli
Solvent-dependent conformations of valinomycin in solution.
Biochemistry 1973;12(3):486-96.
1972: Dinshaw J Patel; C K Woodward; F A Bovey
Proton nuclear magnetic resonance studies of ribonuclease A in H 2 O.
Proceedings of the National Academy of Sciences of the United States of America 1972;69(3):599-602.
1971: A E Tonelli; Dinshaw J Patel; M Goodman; F Naider; H Faulstich; T Wieland
Experimental and calculated conformational characteristics of the cyclic decapeptide antamanide.
Biochemistry 1971;10(17):3211-7.
1971: D R Kearns; Dinshaw J Patel; R G Shulman
High resolution nuclear magnetic resonance studies of hydrogen bonded protons of tRNA in water.
Nature 1971;229(5283):338-9.
1970: Dinshaw J Patel; L Kampa; R G Shulman; T Yamane; B J Wyluda
Proton nuclear magnetic resonance studies of myoglobin in H2O.
Proceedings of the National Academy of Sciences of the United States of America 1970;67(3):1109-15.
1970: R G Shulman; K Wüthrich; T Yamane; Dinshaw J Patel; W E Blumberg
Nuclear magnetic resonance determination of ligand-induced conformational changes in myoglobin.
Journal of molecular biology 1970;53(1):143-57.
1970: Dinshaw J Patel; L Kampa; R G Shulman; T Yamane; M Fujiwara
Proton NMR studies of hemoglobin in H2O.
Biochemical and biophysical research communications 1970;40(5):1224-30.
1970: Dinshaw J Patel; R G Shulman
Spin delocalization in retinals.
Proceedings of the National Academy of Sciences of the United States of America 1970;65(1):31-8.
1969: Dinshaw J Patel
Charge delocalization in the prosthetic group of visual pigments.
Nature 1969;224(5221):799-800.
1969: Dinshaw J Patel
220 MHz proton magnetic resonance spectrum of NADH.
Nature 1969;221(5187):1239-41.
1969: Dinshaw J Patel
220 MHz proton nuclear magnetic resonance spectra of retinals.
Nature 1969;221(5183):825-8.
1966: Dinshaw J Patel; S L Bafna
Separation of coumarins.
Nature 1966;211(5052):963.