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Ketan Patel

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Publications

TOP 3
Frédéric P M Langevin; Gerry P Crossan; Juan I Garaycoechea; Ketan J Patel
[Aldehydes and Fanconi anaemia: the enemy within].
Juan I Garaycoechea; Frederic Langevin; Mark J Arends; Gerry P Crossan; Maria Daly; Ketan J Patel
Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.
Peter Sarkies; Shankar Balasubramanian; Pierre Murat; Ketan J Patel; Lara G Phillips; Julian E Sale
FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA.

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All Publications

2013: Frédéric P M Langevin; Gerry P Crossan; Juan I Garaycoechea; Ketan J Patel
[Aldehydes and Fanconi anaemia: the enemy within].
Médecine sciences : M/S 2013;29(4):361-4.
2012: Juan I Garaycoechea; Frederic Langevin; Mark J Arends; Gerry P Crossan; Maria Daly; Ketan J Patel
Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.
Nature 2012;489(7417):571-5.
2012: Peter Sarkies; Shankar Balasubramanian; Pierre Murat; Ketan J Patel; Lara G Phillips; Julian E Sale
FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA.
Nucleic acids research 2012;40(4):1485-98.
2012: Ian R Kelsall; Judith Langenick; Craig MacKay; Ketan J Patel; Arno F Alpi
The Fanconi anaemia components UBE2T and FANCM are functionally linked to nucleotide excision repair.
PloS one 2012;7(5):e36970.
2012: Gerry P Crossan; Ketan J Patel
The Fanconi anaemia pathway orchestrates incisions at sites of crosslinked DNA.
The Journal of pathology 2012;226(2):326-37.
2011: Ivan V Rosado; Minoru Takata; Gerry P Crossan; Frederic Langevin; Ketan J Patel
Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway.
Nature structural & molecular biology 2011;18(12):1432-4.
2011: Frederic Langevin; Mark J Arends; Gerry P Crossan; Ivan V Rosado; Ketan J Patel
Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.
Nature 2011;475(7354):53-8.
2011: Gerry P Crossan; Louise van der Weyden; Ivan V Rosado; Frederic Langevin; Pierre-Henri L Gaillard; Rebecca E McIntyre; Ferdia Gallagher; Mikko I Kettunen; David Y Lewis; Kevin Brindle; Mark J Arends; David J Adams; Ketan J Patel
Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia.
Nature genetics 2011;43(2):147-52.
2010: Minal Patel; Ketan J Patel; John Caccamese; Domenick P Coletti; John J Sauk; John P Fisher
Characterization of cyclic acetal hydroxyapatite nanocomposites for craniofacial tissue engineering.
Journal of biomedical materials research. Part A 2010;94(2):408-18.
2010: Paul Pace; Georgina Mosedale; Michael R Hodskinson; Ivan V Rosado; Meera Sivasubramaniam; Ketan J Patel
Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway.
Science (New York, N.Y.) 2010;329(5988):219-23.
2010: Minal Patel; Martha W Betz; Elyse Geibel; Ketan J Patel; John Caccamese; Domenick P Coletti; John J Sauk; John P Fisher
Cyclic acetal hydroxyapatite nanocomposites for orbital bone regeneration.
Tissue engineering. Part A 2010;16(1):55-65.
2009: Xiao-Yin Zhang; Judith Langenick; David Traynor; M Madan Babu; Rob R Kay; Ketan J Patel
Xpf and not the Fanconi anaemia proteins or Rev3 accounts for the extreme resistance to cisplatin in Dictyostelium discoideum.
PLoS genetics 2009;5(9):e1000645.
2009: Ivan V Rosado; Wojciech Niedzwiedz; Arno F Alpi; Ketan J Patel
The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair.
Nucleic acids research 2009;37(13):4360-70.
2009: A F Alpi; Ketan J Patel
Monoubiquitylation in the Fanconi anemia DNA damage response pathway.
DNA repair 2009;8(4):430-5.
2008: Arno F Alpi; Paul Pace; M Madan Babu; Ketan J Patel
Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI.
Molecular cell 2008;32(6):767-77.
2008: George R Cybulski; James L Stone; Ketan J Patel
Sir Victor Horsley's contributions to the study and treatment of gunshot wounds of the head.
Neurosurgery 2008;63(4):808-11; discussion 811-2.
2007: Vibe H Oestergaard; Frederic Langevin; Hendrik J Kuiken; Paul Pace; Wojciech Niedzwiedz; Laura J Simpson; Mioko Ohzeki; Minoru Takata; Julian E Sale; Ketan J Patel
Deubiquitination of FANCD2 is required for DNA crosslink repair.
Molecular cell 2007;28(5):798-809.
2007: Arno Alpi; Frederic Langevin; Georgina Mosedale; Yuichi J Machida; Anindya Dutta; Ketan J Patel
UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination.
Molecular and cellular biology 2007;27(24):8421-30.
2007: Ketan J Patel; Hans Joenje
Fanconi anemia and DNA replication repair.
DNA repair 2007;6(7):885-90.
2007: Jonathan P Richardson; Minchuan Wang; Jonathan H Clarke; Ketan J Patel; Robin F Irvine
Genomic tagging of endogenous type IIbeta phosphatidylinositol 5-phosphate 4-kinase in DT40 cells reveals a nuclear localisation.
Cellular signalling 2007;19(6):1309-14.
2007: Ketan J Patel
Fanconi anemia and breast cancer susceptibility.
Nature genetics 2007;39(2):142-3.
2006: Ketan J Patel; Stefan E Pambuccian; Frank G Ondrey; George L Adams; Patrick M Gaffney
Genes associated with early development, apoptosis and cell cycle regulation define a gene expression profile of adenoid cystic carcinoma.
Oral oncology 2006;42(10):994-1004.
2006: Laura J Simpson; Anna-Laura Ross; Dávid Szüts; Cherry A Alviani; Vibe H Oestergaard; Ketan J Patel; Julian E Sale
RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40.
EMBO reports 2006;7(9):927-32.
2005: Georgina Mosedale; Wojciech Niedzwiedz; Arno Alpi; Franco Perrina; Jose Pereira-Leal; Mark Johnson; Frederic Langevin; Paul Pace; Ketan J Patel
The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway.
Nature structural & molecular biology 2005;12(9):763-71.
2005: Wojciech Niedzwiedz; Ketan J Patel
"Dub"bing a tumor suppressor pathway.
Cancer cell 2005;7(2):114-5.
2004: France Léveillé; Eric Blom; Annette L Medhurst; Patrick Bier; El Houari Laghmani; Mark Johnson; Martin A Rooimans; Alexandra Sobeck; Quinten Waisfisz; Fré Arwert; Ketan J Patel; Maureen Hoatlin; Hans Joenje; Johan P de Winter
The Fanconi anemia gene product FANCF is a flexible adaptor protein.
The Journal of biological chemistry 2004;279(38):39421-30.
2004: Wojciech Niedzwiedz; Georgina Mosedale; Mark Johnson; Chong Yi Ong; Paul Pace; Ketan J Patel
The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair.
Molecular cell 2004;15(4):607-20.
2004: Matthew A Ginos; Grier P Page; Bryan S Michalowicz; Ketan J Patel; Sonja E Volker; Stefan E Pambuccian; Frank G Ondrey; George L Adams; Patrick M Gaffney
Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck.
Cancer research 2004;64(1):55-63.
2003: Cassandra J Vandenberg; Fanni Gergely; Chong Yi Ong; Paul Pace; Donna L Mallery; Kevin Hiom; Ketan J Patel
BRCA1-independent ubiquitination of FANCD2.
Molecular cell 2003;12(1):247-54.
2002: Paul Pace; Mark Johnson; Wu Meng Tan; Georgina Mosedale; Chelvin Sng; Maureen Hoatlin; Johan P de Winter; Hans Joenje; Fanni Gergely; Ketan J Patel
FANCE: the link between Fanconi anaemia complex assembly and activity.
The EMBO journal 2002;21(13):3414-23.
2001: Hans Joenje; Ketan J Patel
The emerging genetic and molecular basis of Fanconi anaemia.
Nature reviews. Genetics 2001;2(6):446-57.
1998: LS Friedman; FC Thistlethwaite; Ketan J Patel; VP Yu; H Lee; Ashok R Venkitaraman; K J Abel; Mark B L Carlton; S M Hunter; William H Colledge; Martin J Evans; Bruce A J Ponder
Thymic lymphomas in mice with a truncating mutation in Brca2.
Cancer research 1998;58(7):1338-43.
1998: Ketan J Patel; VP Yu; H Lee; A Corcoran; FC Thistlethwaite; Martin J Evans; William H Colledge; LS Friedman; Bruce A J Ponder; Ashok R Venkitaraman
Involvement of Brca2 in DNA repair.
Molecular cell 1998;1(3):347-57.