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Rakesh Patel

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Chemicals & Drugs

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TOP 3
David W Scott; Rakesh P Patel
Endothelial heterogeneity and adhesion molecules N-glycosylation: Implications in leukocyte trafficking in inflammation.
Dario A Vitturi; J Michael Wyss; Nadiezhda Cantu-Medellin; Balu K Chacko; Yanying Dai; Victoria M Harper; Ning Peng; Chiao-Wang Sun; Bessy Thrash-Williams; Tim M Townes; Rakesh P Patel
Antioxidant functions for the hemoglobin β93 cysteine residue in erythrocytes and in the vascular compartment in vivo.
Yanping Liu; Chiao-Wang Sun; Tim Townes; Jaideep Honavar; Rakesh P Patel
Role of the b93cys, ATP and adenosine in red cell dependent hypoxic vasorelaxation.

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2013: David W Scott; Rakesh P Patel
Endothelial heterogeneity and adhesion molecules N-glycosylation: Implications in leukocyte trafficking in inflammation.
Glycobiology 2013;23(6):622-33.
2013: Dario A Vitturi; J Michael Wyss; Nadiezhda Cantu-Medellin; Balu K Chacko; Yanying Dai; Victoria M Harper; Ning Peng; Chiao-Wang Sun; Bessy Thrash-Williams; Tim M Townes; Rakesh P Patel
Antioxidant functions for the hemoglobin β93 cysteine residue in erythrocytes and in the vascular compartment in vivo.
Free radical biology & medicine 2013;55():119-29.
2013: Yanping Liu; Chiao-Wang Sun; Tim Townes; Jaideep Honavar; Rakesh P Patel
Role of the b93cys, ATP and adenosine in red cell dependent hypoxic vasorelaxation.
International journal of physiology, pathophysiology and pharmacology 2013;5(1):21-31.
2012: Benjamin Y Owusu; Ryan Stapley; Rakesh P Patel
Nitric oxide formation versus scavenging: the red blood cell balancing act.
The Journal of physiology 2012;590(Pt 20):4993-5000.
2012: Brian E Sansbury; Matthew Spite; Yunan Tang; Candice R Holden; Rakesh P Patel; Aruni Bhatnagar; Yang Chen; Timothy D Cummins; Matthew A Harbeson; Jason Hellmann; Bradford G Hill
Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype.
Circulation research 2012;111(9):1176-89.
2012: Andrey A Samal; Giuseppe Squadrito; Chad Steele; Edward M Postlethwait; Kelley M Bradley; Angela Brandon; Stephen Doran; Chad Dunaway; Michelle V Fanucchi; Jaideep Honavar; Yanping Liu; Sadis Matalon; Rakesh P Patel
Administration of nitrite after chlorine gas exposure prevents lung injury: effect of administration modality.
Free radical biology & medicine 2012;53(7):1431-9.
2012: Ryan Stapley; Jordan A Weinberg; Cilina Rodriguez; Scott R Barnum; Angela Brandon; Marianne Cusick; Jeffrey D Kerby; Jack R Lancaster; Marisa B Marques; Benjamin Y Owusu; Rakesh P Patel
Erythrocyte storage increases rates of NO and nitrite scavenging: implications for transfusion-related toxicity.
The Biochemical journal 2012;446(3):499-508.
2012: David W Scott; James G Traylor; Balu K Chacko; Jie Chen; Anthony W Orr; Rakesh P Patel
Role of endothelial N-glycan mannose residues in monocyte recruitment during atherogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(8):e51-9.
2012: Stacey S Kelpke; Brandon Moore; Xinjun Teng; John A Thompson; Liliana Viera; Brett Yancey; Anupam Agarwal; Kelley M Bradley; Angela Brandon; Molly S Bray; Bo Chen; Phillip Chumley; David K Crossman; Devin E Eckhoff; Hughston Head; Rakesh P Patel
Sodium nitrite protects against kidney injury induced by brain death and improves post-transplant function.
Kidney international 2012;82(3):304-13.
2012: Frank L Greenway; Angela Brandon; Douglas R Flanagan; Tony Giordano; David J Lefer; Rakesh P Patel; Benjamin L Predmore; Yang Qiu; Christopher G Kevil
Single-dose pharmacokinetics of different oral sodium nitrite formulations in diabetes patients.
Diabetes technology & therapeutics 2012;14(7):552-60.
2012: Shahid Rameez; Andre F Palmer; Rakesh P Patel; Michael E Paulaitis; Uddyalok Banerjee; Jorge Fontes; Nicole Guzman; Jaideep Honavar
Encapsulation of hemoglobin inside liposomes surface conjugated with poly(ethylene glycol) attenuates their reactions with gaseous ligands and regulates nitric oxide dependent vasodilation.
Biotechnology progress 2012;28(3):636-45.
2012: Asaf Stein; Jeannette E Doeller; Michelle V Fanucchi; David W Kraus; Zhengkuan Mao; Joanna P Morrison; Rakesh P Patel; Edward M Postlethwait; Shannon M Bailey
Metabolic and cardiac signaling effects of inhaled hydrogen sulfide and low oxygen in male rats.
Journal of applied physiology (Bethesda, Md. : 1985) 2012;112(10):1659-69.
2012: Nicole A Terpolilli; Serge C Thal; Vilia Zeisig; Changlian Zhu; Susanne Schwarzmaier; Henryk Barthel; Klas Blomgren; Johannes Boltze; Alexander Drzezga; Doortje C Engel; Hiroharu Kataoka; Seong-Woong Kim; Benjamin Klaesner; Wolfgang M Kuebler; Uta Mamrak; Lilja Meissner; Bjoern Nitzsche; Rakesh P Patel; Nikolaus Plesnila
Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral arterioles.
Circulation research 2012;110(5):727-38.
2012: Chirag V Prajapati; Rakesh P Patel; Bupendra G Prajapati
Formulation, optimization and evaluation of sustained release microsphere of ketoprofen.
Journal of pharmacy & bioallied sciences 2012;4(Suppl 1):S101-3.
2012: Jordan A Weinberg; Loring W Rue; Marianne J Vandromme-Cusick; Jonathan M Angotti; Scott R Barnum; Jeffrey D Kerby; Paul A MacLennan; Louis J Magnotti; Rakesh P Patel
Microvascular response to red blood cell transfusion in trauma patients.
Shock (Augusta, Ga.) 2012;37(3):276-81.
2012: George T El-Ferzli; Rakesh P Patel; Mackenzie Dreher; Namasivayam Ambalavanan
ABO blood group is associated with response to inhaled nitric oxide in neonates with respiratory failure.
PloS one 2012;7(9):e45164.
2012: Wei Li; Yuliang Liu; Zihui Meng; Rakesh P Patel; John D Lang
The hepatoprotective effect of sodium nitrite on cold ischemia-reperfusion injury.
Journal of transplantation 2012;2012():635179.
2011: Balu K Chacko; Robert T Chandler; David W Scott; Rakesh P Patel
Endothelial surface N-glycans mediate monocyte adhesion and are targets for anti-inflammatory effects of peroxisome proliferator-activated receptor γ ligands.
The Journal of biological chemistry 2011;286(44):38738-47.
2011: Rakesh P Patel
Losing control over adenosine 5'-triphosphate release: implications for the red blood cell storage lesion.
Critical care medicine 2011;39(11):2573-4.
2011: Nadiezhda Cantu-Medellin; Scott Dorman; Yiping Jia; Serena Murphy; Andre F Palmer; Cilina Rodriguez; Sruti Shiva; Dario A Vitturi; Yipin Zhou; Rakesh P Patel
Effects of T- and R-state stabilization on deoxyhemoglobin-nitrite reactions and stimulation of nitric oxide signaling.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2011;25(2):59-69.
2011: Jaideep Honavar; Akhil Maheshwari; Sadis Matalon; Krishnan MohanKumar; Joann Balanay; Kelley M Bradley; Angela Brandon; Edward M Postlethwait; Andrey A Samal; Giuseppe Squadrito; Rakesh P Patel
Chlorine gas exposure causes systemic endothelial dysfunction by inhibiting endothelial nitric oxide synthase-dependent signaling.
American journal of respiratory cell and molecular biology 2011;45(2):419-25.
2011: John T Anderson; Meiqin Zeng; Qian Li; Ryan Stapley; Doyle Ray Moore; Balachandra Chenna; Naomi S Fineberg; Jaroslaw Zmijewski; Isam-Eldin Eltoum; Gene P Siegal; Amit Gaggar; Stephen Barnes; Sadanandan E Velu; Victor J Thannickal; Edward Abraham; Rakesh P Patel; Jack R Lancaster; David D Chaplin; Mark T Dransfield; Jessy S Deshane
Elevated levels of NO are localized to distal airways in asthma.
Free radical biology & medicine 2011;50(11):1679-88.
2011: Jordan A Weinberg; Scott R Barnum; Rakesh P Patel
Red blood cell age and potentiation of transfusion-related pathology in trauma patients.
Transfusion 2011;51(4):867-73.
2011: Amit K Yadav; Stephen F Doran; Andrey A Samal; Ruchita Sharma; Kokilavani Vedagiri; Edward M Postlethwait; Giuseppe Squadrito; Michelle V Fanucchi; L Jackson Roberts; Rakesh P Patel; Sadis Matalon
Mitigation of chlorine gas lung injury in rats by postexposure administration of sodium nitrite.
American journal of physiology. Lung cellular and molecular physiology 2011;300(3):L362-9.
2011: Mai E Shoman; Jenna F DuMond; T Scott Isbell; J H Crawford; Angela Brandon; Jaideep Honovar; Dario A Vitturi; C R White; Rakesh P Patel; S Bruce King
Acyloxy nitroso compounds as nitroxyl (HNO) donors: kinetics, reactions with thiols, and vasodilation properties.
Journal of medicinal chemistry 2011;54(4):1059-70.
2011: Rakesh P Patel; Neil Hogg; Daniel B Kim-Shapiro
The potential role of the red blood cell in nitrite-dependent regulation of blood flow.
Cardiovascular research 2011;89(3):507-15.
2011: Sruti Shiva; Tienush Rassaf; Rakesh P Patel; Mark T Gladwin
The detection of the nitrite reductase and NO-generating properties of haemoglobin by mitochondrial inhibition.
Cardiovascular research 2011;89(3):566-73.
2011: Christopher B Pattillo; Shyamal C Bir; Billy G Branch; Eric Greber; xinggui shen; Sibile Pardue; Rakesh P Patel; Christopher Kevil
Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db/Db diabetic mouse hind-limb model by decreasing oxidative stress.
Free radical biology & medicine 2011;50(2):262-9.
2010: Stéphane P Dufour; Rakesh P Patel; Angela Brandon; Xinjun Teng; James Pearson; Horace Barker; Leena Ali; Ada H Y Yuen; Ryszard T Smolenski; José González-Alonso
Erythrocyte-dependent regulation of human skeletal muscle blood flow: role of varied oxyhemoglobin and exercise on nitrite, S-nitrosohemoglobin, and ATP.
American journal of physiology. Heart and circulatory physiology 2010;299(6):H1936-46.
2010: Rakesh P Patel; Phillip Mucksavage; Parvati Ramchandani; PM Hanno; S Bruce Malkowicz
Idiopathic partial thrombosis of the corpus cavernosum.
Urology 2010;76(6):1373-4.
2010: Christopher Kevil; Rakesh P Patel
S-Nitrosothiol biology and therapeutic potential in metabolic disease.
Current opinion in investigational drugs (London, England : 2000) 2010;11(10):1127-34.
2010: Christopher B Pattillo; Sibile Pardue; xinggui shen; Kai Fang; Will Langston; David Jourd'heuil; Terrance J Kavanagh; Rakesh P Patel; Christopher Kevil
ICAM-1 cytoplasmic tail regulates endothelial glutathione synthesis through a NOX4/PI3-kinase-dependent pathway.
Free radical biology & medicine 2010;49(6):1119-28.
2010: Nicholas K H Khoo; C Roger White; Lucas Pozzo-Miller; Fen Zhou; Chad Constance; Takafumi Inoue; Rakesh P Patel; Dale A Parks
Dietary flavonoid quercetin stimulates vasorelaxation in aortic vessels.
Free radical biology & medicine 2010;49(3):339-47.
2010: Andrey Samal; Jaideep Honovar; C Roger White; Rakesh P Patel
Potential for chlorine gas-induced injury in the extrapulmonary vasculature.
Proceedings of the American Thoracic Society 2010;7(4):290-3.
2010: Prasanna K Venkatesh; Christopher B Pattillo; Billy Branch; Jay Hood; Steven Thoma; Sandra Illum; Sibile Pardue; Xinjun Teng; Rakesh P Patel; Christopher Kevil
Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway.
Cardiovascular research 2010;85(4):661-70.
2010: Rakesh P Patel; Stephen Barnes
Isoflavones and PPAR Signaling: A Critical Target in Cardiovascular, Metastatic, and Metabolic Disease.
PPAR research 2010;2010():153252.
2009: N A Patel; N J Patel; Rakesh P Patel
Comparative development and evaluation of topical gel and cream formulations of psoralen.
Drug discoveries & therapeutics 2009;3(5):234-42.
2009: Cilina Rodriguez; Dario A Vitturi; Jin He; Marianne Vandromme; Angela Brandon; Anne Hutchings; Loring W Rue; Jeffrey D Kerby; Rakesh P Patel
Sodium nitrite therapy attenuates the hypertensive effects of HBOC-201 via nitrite reduction.
The Biochemical journal 2009;422(3):423-32.
2009: Tracy A Prime; Frances H Blaikie; Cameron Evans; Sergiy M Nadtochiy; Andrew M James; Christina C Dahm; Dario A Vitturi; Rakesh P Patel; C Robin Hiley; Irina Abakumova; Raquel Requejo; Edward T Chouchani; Thomas R Hurd; John F Garvey; Cormac T Taylor; Paul S Brookes; Robin A J Smith; Michael P Murphy
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(26):10764-9.
2009: Dario A Vitturi; Xinjun Teng; José C Toledo; Sadis Matalon; Jack R Lancaster; Rakesh P Patel
Regulation of nitrite transport in red blood cells by hemoglobin oxygen fractional saturation.
American journal of physiology. Heart and circulatory physiology 2009;296(5):H1398-407.
2009: Akhil Maheshwari; Svetlana Akalovich; Michael B Fallon; Cheryl R Killingsworth; Rakesh P Patel; David A Randolph; Sadiq S Shaik; Brian Sims; Nikolai N Voitenok; Robin K Ohls
Developmental changes in circulating IL-8/CXCL8 isoforms in neonates.
Cytokine 2009;46(1):12-6.
2009: Sadiq S Shaik; Thomas D Soltau; Balagangadhar Totapally; Nikolai N Voitenok; William W Andrews; Mohammad Athar; Gaurav Chaturvedi; Michael B Fallon; James Hagood; Cheryl R Killingsworth; Rakesh P Patel; Akhil Maheshwari
Low intensity shear stress increases endothelial ELR+ CXC chemokine production via a focal adhesion kinase-p38{beta} MAPK-NF-{kappa}B pathway.
The Journal of biological chemistry 2009;284(9):5945-55.
2009: Nikunjana A Patel; Natvar J Patel; Rakesh P Patel
Design and evaluation of transdermal drug delivery system for curcumin as an anti-inflammatory drug.
Drug development and industrial pharmacy 2009;35(2):234-42.
2009: Nikunjana A Patel; Natvar J Patel; Rakesh P Patel
Formulation and evaluation of curcumin gel for topical application.
Pharmaceutical development and technology 2009;14(1):80-9.
2008: Rakesh P Patel; Thomas F Kolon; Dale S Huff; Michael C Carr; Stephen A Zderic; Douglas A Canning; Howard M Snyder
Cryptorchid testis histopathology in myelomeningocele patients.
Journal of pediatric urology 2008;4(6):434-7.
2008: Christopher Kevil; Rakesh P Patel
Preserving vessel function during ischemic disease: new possibilities of inorganic nitrite therapy.
Expert review of cardiovascular therapy 2008;6(9):1175-9.
2008: Yuliang Liu; Balu K Chacko; Ana Ricksecker; Roman Shingarev; Eric Andrews; Rakesh P Patel; John D Lang
Modulatory effects of hypercapnia on in vitro and in vivo pulmonary endothelial-neutrophil adhesive responses during inflammation.
Cytokine 2008;44(1):108-17.
2008: T Scott Isbell; Chiao-Wang Sun; Li-Chen Wu; Xinjun Teng; Dario A Vitturi; Billy G Branch; Christopher Kevil; Ning Peng; J Michael Wyss; Namasivayam Ambalavanan; Lisa Schwiebert; Jinxiang Ren; Kevin M Pawlik; Matthew B Renfrow; Rakesh P Patel; Tim M Townes
SNO-hemoglobin is not essential for red blood cell-dependent hypoxic vasodilation.
Nature medicine 2008;14(7):773-7.
2008: Dinesh Kumar; Billy G Branch; Christopher B Pattillo; Jay Hood; Stephen Thoma; Stephen Simpson; Sandra Illum; Neeraj Arora; John H Chidlow; Will Langston; Xinjun Teng; David J Lefer; Rakesh P Patel; Christopher Kevil
Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(21):7540-5.
2008: Pasquale Casale; Rakesh P Patel; Thomas F Kolon
Nerve sparing robotic extravesical ureteral reimplantation.
The Journal of urology 2008;179(5):1987-9; discussion 1990.
2008: Mark T Gladwin; Rakesh P Patel
The role of red blood cells and hemoglobin-nitric oxide interactions on blood flow.
American journal of respiratory cell and molecular biology 2008;38(2):125-6.
2007: Gloria A Benavides; Giuseppe Squadrito; Robert W Mills; Hetal D Patel; T Scott Isbell; Rakesh P Patel; Victor Darley-Usmar; Jeannette E Doeller; David Kraus
Hydrogen sulfide mediates the vasoactivity of garlic.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(46):17977-82.
2007: T Scott Isbell; Mark T Gladwin; Rakesh P Patel
Hemoglobin oxygen fractional saturation regulates nitrite-dependent vasodilation of aortic ring bioassays.
American journal of physiology. Heart and circulatory physiology 2007;293(4):H2565-72.
2007: John D Lang; Xinjun Teng; Phillip Chumley; Jack H Crawford; T Scott Isbell; Balu K Chacko; Yuliang Liu; Nirag C Jhala; D Ralph Crowe; Alvin B Smith; Richard C Cross; Luc Frenette; Eric E Kelley; Diana W Wilhite; Cheryl R Hall; Grier P Page; Michael B Fallon; J Steven Bynon; Devin E Eckhoff; Rakesh P Patel
Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation.
The Journal of clinical investigation 2007;117(9):2583-91.
2007: Annamalai Senthilkumar; Ray D Smith; Jayant Khitha; Neeraj Arora; Srikar Veerareddy; Will Langston; John H Chidlow; Shayne C Barlow; Xinjun Teng; Rakesh P Patel; David J Lefer; Christopher Kevil
Sildenafil promotes ischemia-induced angiogenesis through a PKG-dependent pathway.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(9):1947-54.
2007: Ashwani Kumar; Jose C Toledo; Rakesh P Patel; Jack R Lancaster; Adrie J C Steyn
Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(28):11568-73.
2007: Liping Tang; Bao Luo; Rakesh P Patel; Yiqun Ling; Junlan Zhang; Michael B Fallon
Modulation of pulmonary endothelial endothelin B receptor expression and signaling: implications for experimental hepatopulmonary syndrome.
American journal of physiology. Lung cellular and molecular physiology 2007;292(6):L1467-72.
2007: Jeffrey R Koenitzer; T Scott Isbell; Hetal D Patel; Gloria A Benavides; Dale A Dickinson; Rakesh P Patel; Victor Darley-Usmar; Jack R Lancaster; Jeannette E Doeller; David Kraus
Hydrogen sulfide mediates vasoactivity in an O2-dependent manner.
American journal of physiology. Heart and circulatory physiology 2007;292(4):H1953-60.
2007: Will Langston; John H Chidlow; Blake A Booth; Shayne C Barlow; David J Lefer; Rakesh P Patel; Christopher Kevil
Regulation of endothelial glutathione by ICAM-1 governs VEGF-A-mediated eNOS activity and angiogenesis.
Free radical biology & medicine 2007;42(5):720-9.
2007: Junlan Zhang; Yiqun Ling; Liping Tang; Bao Luo; Balu K Chacko; Rakesh P Patel; Michael B Fallon
Pentoxifylline attenuation of experimental hepatopulmonary syndrome.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(3):949-55.
2007: Balu K Chacko; Robert T Chandler; Tracy L D'Alessandro; Ameya N Mundhekar; Nicholas K H Khoo; Nigel Botting; Stephen Barnes; Rakesh P Patel
Anti-inflammatory effects of isoflavones are dependent on flow and human endothelial cell PPARgamma.
The Journal of nutrition 2007;137(2):351-6.
2007: Thanh N Huynh; Balu K Chacko; Xinjun Teng; Brigitta C Brott; Michael Allon; Stacey S Kelpke; John A Thompson; Rakesh P Patel; Andreas S Anayiotos
Effects of venous needle turbulence during ex vivo hemodialysis on endothelial morphology and nitric oxide formation.
Journal of biomechanics 2007;40(10):2158-66.
2007: Heather M Pruitt; Will Langston; Christopher Kevil; Rakesh P Patel
ICAM-1 cross-linking stimulates endothelial glutathione synthesis.
Antioxidants & redox signaling 2007;9(1):159-64.
2006: Taixing Cui; Francisco J Schopfer; Jifeng Zhang; Kai Chen; Tomonaga Ichikawa; Paul Baker; Carlos Batthyany; Balu K Chacko; Xu Feng; Rakesh P Patel; Anupam Agarwal; Bruce Freeman; Chen Lab
Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators.
The Journal of biological chemistry 2006;281(47):35686-98.
2006: Mark T Gladwin; Nicolaas J H Raat; Sruti Shiva; Cameron Dezfulian; Neil Hogg; Daniel B Kim-Shapiro; Rakesh P Patel
Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation.
American journal of physiology. Heart and circulatory physiology 2006;291(5):H2026-35.
2006: Xin Sha; T Scott Isbell; Rakesh P Patel; Cynthia S Day; S Bruce King
Hydrolysis of acyloxy nitroso compounds yields nitroxyl (HNO).
Journal of the American Chemical Society 2006;128(30):9687-92.
2006: Tara K Burke; Xinjun Teng; Rakesh P Patel; Ann L Baldwin
Effects of S-nitrosation on hemoglobin-induced microvascular damage.
Antioxidants & redox signaling 2006;8(7-8):1093-101.
2006: Lan Chen; Rakesh P Patel; Xinjun Teng; Charles A Bosworth; Jack R Lancaster; Sadis Matalon
Mechanisms of cystic fibrosis transmembrane conductance regulator activation by S-nitrosoglutathione.
The Journal of biological chemistry 2006;281(14):9190-9.
2006: Mahesh Basireddy; T Scott Isbell; Xinjun Teng; Rakesh P Patel; Anupam Agarwal
Effects of sodium nitrite on ischemia-reperfusion injury in the rat kidney.
American journal of physiology. Renal physiology 2006;290(4):F779-86.
2006: Jack H Crawford; T Scott Isbell; Zhi Huang; Sruti Shiva; Balu K Chacko; Alan N Schechter; Victor Darley-Usmar; Jeffrey D Kerby; John D Lang; David Kraus; Chien Ho; Mark T Gladwin; Rakesh P Patel
Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation.
Blood 2006;107(2):566-74.
2005: Mark T Gladwin; Alan N Schechter; Daniel B Kim-Shapiro; Rakesh P Patel; Neil Hogg; Sruti Shiva; Richard O Cannon; Malte Kelm; David A Wink; Michael G Espey; Edward H Oldfield; Ryszard M Pluta; Bruce Freeman; Jack R Lancaster; Martin Feelisch; Jon O Lundberg
The emerging biology of the nitrite anion.
Nature chemical biology 2005;1(6):308-14.
2005: Rakesh P Patel; Thomas F Kolon; Dale S Huff; Michael C Carr; Stephen A Zderic; Douglas A Canning; Howard M Snyder
Testicular microlithiasis and antisperm antibodies following testicular biopsy in boys with cryptorchidism.
The Journal of urology 2005;174(5):2008-10; discussion 2010.
2005: Anne Jeffers; Xiuli Xu; Kris T Huang; Man Cho; Neil Hogg; Rakesh P Patel; Daniel B Kim-Shapiro
Hemoglobin mediated nitrite activation of soluble guanylyl cyclase.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2005;142(2):130-5.
2005: Kris T Huang; Agnes Keszler; Neil Patel; Rakesh P Patel; Mark T Gladwin; Daniel B Kim-Shapiro; Neil Hogg
The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry.
The Journal of biological chemistry 2005;280(35):31126-31.
2005: Zhi Huang; Sruti Shiva; Daniel B Kim-Shapiro; Rakesh P Patel; Lorna A Ringwood; Cynthia E Irby; Kris T Huang; Chien Ho; Neil Hogg; Alan N Schechter; Mark T Gladwin
Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control.
The Journal of clinical investigation 2005;115(8):2099-107.
2005: Balu K Chacko; Robert T Chandler; Ameya N Mundhekar; Nicholas K H Khoo; Heather M Pruitt; Dennis F Kucik; Dale A Parks; Christopher Kevil; Stephen Barnes; Rakesh P Patel
Revealing anti-inflammatory mechanisms of soy isoflavones by flow: modulation of leukocyte-endothelial cell interactions.
American journal of physiology. Heart and circulatory physiology 2005;289(2):H908-15.
2005: Jeannette E Doeller; T Scott Isbell; Gloria A Benavides; Jeffrey R Koenitzer; Hetal Patel; Rakesh P Patel; Jack R Lancaster; Victor Darley-Usmar; David Kraus
Polarographic measurement of hydrogen sulfide production and consumption by mammalian tissues.
Analytical biochemistry 2005;341(1):40-51.
2005: Francisco J Schopfer; Paul Baker; Gregory Giles; Phillip Chumley; Carlos Batthyany; Jack Crawford; Rakesh P Patel; Neil Hogg; Bruce P Branchaud; Jack R Lancaster; Bruce Freeman
Fatty acid transduction of nitric oxide signaling. Nitrolinoleic acid is a hydrophobically stabilized nitric oxide donor.
The Journal of biological chemistry 2005;280(19):19289-97.
2005: Mark R Duranski; James J M Greer; André Dejam; Sathya Jaganmohan; Neil Hogg; William Langston; Rakesh P Patel; Shaw-Fang Yet; Xunde Wang; Christopher Kevil; Mark T Gladwin; David J Lefer
Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver.
The Journal of clinical investigation 2005;115(5):1232-40.
2005: Rakesh P Patel; Aseem R Shukla; Nicholas T Leone; Michael C Carr; Douglas A Canning
Split onlay skin flap for the salvage hypospadias repair.
The Journal of urology 2005;173(5):1718-20.
2005: Rakesh P Patel; Aseem R Shukla; James C (Christopher) Austin; Douglas A Canning
Modified tubularized transverse preputial island flap repair for severe proximal hypospadias.
BJU international 2005;95(6):901-4.
2005: Aseem R Shukla; Jeffrey Cooper; Rakesh P Patel; Michael C Carr; Douglas A Canning; Stephen A Zderic; Howard M Snyder
Prenatally detected primary megaureter: a role for extended followup.
The Journal of urology 2005;173(4):1353-6.
2005: Tracy L D'Alessandro; Brenda J Boersma-Maland; T Greg Peterson; Jeffrey N Sfakianos; Jeevan K Prasain; Rakesh P Patel; Victor Darley-Usmar; Nigel Botting; Stephen Barnes
Metabolism of phytoestrogen conjugates.
Methods in enzymology 2005;400():316-42.
2005: Jayvadan K Patel; Rakesh P Patel; Avani F Amin; Madhabhai M Patel
Formulation and evaluation of mucoadhesive glipizide microspheres.
AAPS PharmSciTech 2005;6(1):E49-55.
2005: T Scott Isbell; Jeffrey R Koenitzer; Jack H Crawford; C Roger White; David Kraus; Rakesh P Patel
Assessing NO-dependent vasodilatation using vessel bioassays at defined oxygen tensions.
Methods in enzymology 2005;396():553-68.
2005: Daniel B Kim-Shapiro; Mark T Gladwin; Rakesh P Patel; Neil Hogg
The reaction between nitrite and hemoglobin: the role of nitrite in hemoglobin-mediated hypoxic vasodilation.
Journal of inorganic biochemistry 2005;99(1):237-46.
2004: Jack H Crawford; Balu K Chacko; Christopher Kevil; Rakesh P Patel
The red blood cell and vascular function in health and disease.
Antioxidants & redox signaling 2004;6(6):992-9.
2004: Rakesh P Patel; Aseem R Shukla; Howard M Snyder
The island tube and island onlay hypospadias repairs offer excellent long-term outcomes: a 14-year followup.
The Journal of urology 2004;172(4 Pt 2):1717-9; discussion 1719.
2004: Aseem R Shukla; Rakesh P Patel; Douglas A Canning
The 2-stage hypospadias repair. Is it a misnomer?
The Journal of urology 2004;172(4 Pt 2):1714-6; discussion 1716.
2004: Catherine Fenster; Victor Darley-Usmar; Aimee Landar; Barbara A Gower; Roland L Weinsier; Gary R Hunter; Rakesh P Patel
Weight loss and race modulate nitric oxide metabolism in overweight women.
Free radical biology & medicine 2004;37(5):695-702.
2004: Jack H Crawford; Balu K Chacko; Heather M Pruitt; Barbora Piknova; Neil Hogg; Rakesh P Patel
Transduction of NO-bioactivity by the red blood cell in sepsis: novel mechanisms of vasodilation during acute inflammatory disease.
Blood 2004;104(5):1375-82.
2004: Daniel B Kim-Shapiro; Rakesh P Patel; Alan N Schechter; Mark T Gladwin; Richard O Cannon; Neil Hogg
How do red blood cells dilate blood vessels?--Reply.
Circulation research 2004;95(3):e10.
2004: Thomas F Kolon; Rakesh P Patel; Dale S Huff
Cryptorchidism: diagnosis, treatment, and long-term prognosis.
The Urologic clinics of North America 2004;31(3):469-80, viii-ix.
2004: Aseem R Shukla; Rakesh P Patel; Douglas A Canning
Hypospadias.
The Urologic clinics of North America 2004;31(3):445-60, viii.
2004: Christopher Kevil; Heather M Pruitt; T J Kavanagh; Jasmine Wilkerson; Federico M Farin; Douglas R Moellering; Victor Darley-Usmar; Daniel C Bullard; Rakesh P Patel
Regulation of endothelial glutathione by ICAM-1: implications for inflammation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(11):1321-3.
2004: Christopher Kevil; A Wayne Orr; Will Langston; Kathryn Mickett; Joanne E Murphy-Ullrich; Rakesh P Patel; Dennis F Kucik; Daniel C Bullard
Intercellular adhesion molecule-1 (ICAM-1) regulates endothelial cell motility through a nitric oxide-dependent pathway.
The Journal of biological chemistry 2004;279(18):19230-8.
2004: Sruti Shiva; Jack H Crawford; Anup Ramachandran; Erin K Ceaser; Tess Hillson; Paul S Brookes; Rakesh P Patel; Victor Darley-Usmar
Mechanisms of the interaction of nitroxyl with mitochondria.
The Biochemical journal 2004;379(Pt 2):359-66.
2004: Mark T Gladwin; Jack H Crawford; Rakesh P Patel
The biochemistry of nitric oxide, nitrite, and hemoglobin: role in blood flow regulation.
Free radical biology & medicine 2004;36(6):707-17.
2004: C Roger White; Dale A Parks; Rakesh P Patel; Jonathan Shelton; Margaret M Tarpey; Bruce Freeman; Victor Darley-Usmar
L-Arginine inhibits xanthine oxidase-dependent endothelial dysfunction in hypercholesterolemia.
FEBS letters 2004;561(1-3):94-8.
2004: Rakesh P Patel; Mark T Gladwin
Physiologic, pathologic and therapeutic implications for hemoglobin interactions with nitric oxide.
Free radical biology & medicine 2004;36(4):399-401.
2004: Jack H Crawford; Balu K Chacko; Rakesh P Patel
Regulation of vascular function by haemoglobin.
Biochemical Society symposium 2004;(71):135-42.
2004: Sruti Shiva; Douglas R Moellering; Anup Ramachandran; Anna-Liisa Levonen; Aimee Landar; Aparna Venkatraman; Erin K Ceaser; Elena Ulasova; Jack H Crawford; Paul S Brookes; Rakesh P Patel; Victor Darley-Usmar
Redox signalling: from nitric oxide to oxidized lipids.
Biochemical Society symposium 2004;(71):107-20.
2003: Brenda J Boersma; Tracy L D'Alessandro; Matthew R Benton; Marion Kirk; Landon S Wilson; Jeevan K Prasain; Nigel Botting; Stephen Barnes; Victor Darley-Usmar; Rakesh P Patel
Neutrophil myeloperoxidase chlorinates and nitrates soy isoflavones and enhances their antioxidant properties.
Free radical biology & medicine 2003;35(11):1417-30.
2003: Kenyatta Cosby; Kristine S Partovi; Jack H Crawford; Rakesh P Patel; Christopher D Reiter; Sabrina Martyr; Benjamin K Yang; Myron A Waclawiw; Gloria Zalos; Xiuli Xu; Kris T Huang; Howard Shields; Daniel B Kim-Shapiro; Alan N Schechter; Richard O Cannon; Mark T Gladwin
Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation.
Nature medicine 2003;9(12):1498-505.
2003: Paul S Brookes; David Kraus; Sruti Shiva; Jeannette E Doeller; Maria Cecilia Barone; Rakesh P Patel; Jack R Lancaster; Victor Darley-Usmar
Control of mitochondrial respiration by NO*, effects of low oxygen and respiratory state.
The Journal of biological chemistry 2003;278(34):31603-9.
2003: Trudy L Cornwell; Erin K Ceaser; Jie Li; Kevin L Marrs; Victor Darley-Usmar; Rakesh P Patel
S-nitrosothiols inhibit uterine smooth muscle cell proliferation independent of metabolism to NO and cGMP formation.
American journal of physiology. Cell physiology 2003;284(6):C1516-24.
2003: Jack H Crawford; C Roger White; Rakesh P Patel
Vasoactivity of S-nitrosohemoglobin: role of oxygen, heme, and NO oxidation states.
Blood 2003;101(11):4408-15.
2003: Dale A Dickinson; Douglas R Moellering; Karen E Iles; Rakesh P Patel; Anna-Liisa Levonen; Amanda F Wigley; Victor Darley-Usmar; Henry Jay Forman
Cytoprotection against oxidative stress and the regulation of glutathione synthesis.
Biological chemistry 2003;384(4):527-37.
2002: Steven Deem; Joung Uk Kim; Belur N Manjula; Seetharama A Acharya; Mark E Kerr; Rakesh P Patel; Mark T Gladwin; Erik R Swenson
Effects of S-nitrosation and cross-linking of hemoglobin on hypoxic pulmonary vasoconstriction in isolated rat lungs.
Circulation research 2002;91(7):626-32.
2002: Chris E Cooper; Rakesh P Patel; Paul S Brookes; Victor Darley-Usmar
Nanotransducers in cellular redox signaling: modification of thiols by reactive oxygen and nitrogen species.
Trends in biochemical sciences 2002;27(10):489-92.
2002: Adrian J Hobbs; Mark T Gladwin; Rakesh P Patel; D Lyn H Williams; Anthony R Butler
Haemoglobin: NO transporter, NO inactivator or NOne of the above?
Trends in pharmacological sciences 2002;23(9):406-11.
2002: Catherine Fenster; Roland L Weinsier; Victor Darley-Usmar; Rakesh P Patel
Obesity, aerobic exercise, and vascular disease: the role of oxidant stress.
Obesity research 2002;10(9):964-8.
2002: Anup Ramachandran; Douglas R Moellering; Young-Mi Go; Sruti Shiva; Anna-Liisa Levonen; Hanjoong Jo; Rakesh P Patel; Sampath Parthasarathy; Victor Darley-Usmar
Activation of c-Jun N-terminal kinase and apoptosis in endothelial cells mediated by endogenous generation of hydrogen peroxide.
Biological chemistry 2002;383(3-4):693-701.
2002: Douglas R Moellering; Anna-Liisa Levonen; Young-Mi Go; Rakesh P Patel; Dale A Dickinson; Henry Jay Forman; Victor Darley-Usmar
Induction of glutathione synthesis by oxidized low-density lipoprotein and 1-palmitoyl-2-arachidonyl phosphatidylcholine: protection against quinone-mediated oxidative stress.
The Biochemical journal 2002;362(Pt 1):51-9.
2002: Paul S Brookes; Sruti Shiva; Rakesh P Patel; Victor Darley-Usmar
Measurement of mitochondrial respiratory thresholds and the control of respiration by nitric oxide.
Methods in enzymology 2002;359():305-19.
2001: Mutay Aslan; Thomas M Ryan; B Adler; Tim M Townes; Dale A Parks; J A Thompson; Albert Tousson; M T Gladwin; Rakesh P Patel; Margaret M Tarpey; I Batinic-Haberle; C Roger White; Bruce Freeman
Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15215-20.
2001: Rakesh P Patel; Brenda J Boersma; Jack H Crawford; Neil Hogg; Marion Kirk; B Kalyanaraman; Dale A Parks; Stephen Barnes; Victor Darley-Usmar
Antioxidant mechanisms of isoflavones in lipid systems: paradoxical effects of peroxyl radical scavenging.
Free radical biology & medicine 2001;31(12):1570-81.
2001: Young-Mi Go; Anna-Liisa Levonen; Douglas R Moellering; Anup Ramachandran; Rakesh P Patel; Hanjoong Jo; Victor Darley-Usmar
Endothelial NOS-dependent activation of c-Jun NH(2)- terminal kinase by oxidized low-density lipoprotein.
American journal of physiology. Heart and circulatory physiology 2001;281(6):H2705-13.
2001: Christopher Kevil; Rakesh P Patel; Daniel C Bullard
Essential role of ICAM-1 in mediating monocyte adhesion to aortic endothelial cells.
American journal of physiology. Cell physiology 2001;281(5):C1442-7.
2001: R Marley; Rakesh P Patel; N Orie; Erin K Ceaser; Victor Darley-Usmar; K Moore
Formation of nanomolar concentrations of S-nitroso-albumin in human plasma by nitric oxide.
Free radical biology & medicine 2001;31(5):688-96.
2001: Sruti Shiva; Paul S Brookes; Rakesh P Patel; Peter G Anderson; Victor Darley-Usmar
Nitric oxide partitioning into mitochondrial membranes and the control of respiration at cytochrome c oxidase.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(13):7212-7.
2001: Anna-Liisa Levonen; Rakesh P Patel; Paul S Brookes; Young-Mi Go; Hanjoong Jo; Sampath Parthasarathy; Peter G Anderson; Victor Darley-Usmar
Mechanisms of cell signaling by nitric oxide and peroxynitrite: from mitochondria to MAP kinases.
Antioxidants & redox signaling 2001;3(2):215-29.
2001: Ralf Binsack; Brenda J Boersma; Rakesh P Patel; Marion Kirk; C Roger White; Victor Darley-Usmar; Stephen Barnes; Fen Zhou; Dale A Parks
Enhanced antioxidant activity after chlorination of quercetin by hypochlorous acid.
Alcoholism, clinical and experimental research 2001;25(3):434-43.
2001: Brenda J Boersma; Rakesh P Patel; Nigel Botting; C Roger White; D Parks; Stephen Barnes; Victor Darley-Usmar
Formation of novel bioactive metabolites from the reactions of pro-inflammatory oxidants with polyphenolics.
BioFactors (Oxford, England) 2001;15(2-4):79-81.
2000: Netanya Y Spencer; H Zeng; Rakesh P Patel; Neil Hogg
Reaction of S-nitrosoglutathione with the heme group of deoxyhemoglobin.
The Journal of biological chemistry 2000;275(47):36562-7.
2000: Rakesh P Patel; Anna-Liisa Levonen; Jack H Crawford; Victor Darley-Usmar
Mechanisms of the pro- and anti-oxidant actions of nitric oxide in atherosclerosis.
Cardiovascular research 2000;47(3):465-74.
2000: Rakesh P Patel; Douglas R Moellering; J Murphy-Ullrich; Hanjoong Jo; J S Beckman; Victor Darley-Usmar
Cell signaling by reactive nitrogen and oxygen species in atherosclerosis.
Free radical biology & medicine 2000;28(12):1780-94.
2000: Rakesh P Patel
Biochemical aspects of the reaction of hemoglobin and NO: implications for Hb-based blood substitutes.
Free radical biology & medicine 2000;28(10):1518-25.
1999: Young-Mi Go; Rakesh P Patel; MC Maland; H Park; J S Beckman; Victor Darley-Usmar; Hanjoong Jo
Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase.
The American journal of physiology 1999;277(4 Pt 2):H1647-53.
1999: Brenda J Boersma; Rakesh P Patel; Marion Kirk; P L Jackson; Donald D Muccio; Victor Darley-Usmar; Stephen Barnes
Chlorination and nitration of soy isoflavones.
Archives of biochemistry and biophysics 1999;368(2):265-75.
1999: Rakesh P Patel; Neil Hogg; Netanya Y Spencer; B Kalyanaraman; Sadis Matalon; Victor Darley-Usmar
Biochemical characterization of human S-nitrosohemoglobin. Effects on oxygen binding and transnitrosation.
The Journal of biological chemistry 1999;274(22):15487-92.
1999: Rakesh P Patel; Joanne McAndrew; Hassan Sellak; C R White; Hanjoong Jo; Bruce Freeman; Victor Darley-Usmar
Biological aspects of reactive nitrogen species.
Biochimica et biophysica acta 1999;1411(2-3):385-400.
1999: Douglas R Moellering; J Mc Andrew; Rakesh P Patel; Henry Jay Forman; R T Mulcahy; Hanjoong Jo; Victor Darley-Usmar
The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: a role for gamma-glutamylcysteine synthetase and gamma-glutamyl transpeptidase.
FEBS letters 1999;448(2-3):292-6.
1999: Rakesh P Patel; Victor Darley-Usmar
Molecular mechanisms of the copper dependent oxidation of low-density lipoprotein.
Free radical research 1999;30(1):1-9.
1999: C Roger White; Rakesh P Patel; Victor Darley-Usmar
Nitric oxide donor generation from reactions of peroxynitrite.
Methods in enzymology 1999;301():288-98.
1998: Douglas R Moellering; Joanne McAndrew; Rakesh P Patel; Trudy L Cornwell; Thomas M Lincoln; Xu Cao; J L Messina; Henry Jay Forman; Hanjoong Jo; Victor Darley-Usmar
Nitric oxide-dependent induction of glutathione synthesis through increased expression of gamma-glutamylcysteine synthetase.
Archives of biochemistry and biophysics 1998;358(1):74-82.
1997: C R White; Douglas R Moellering; Rakesh P Patel; M Kirk; S Barnes; Victor Darley-Usmar
Formation of the NO donors glyceryl mononitrate and glyceryl mononitrite from the reaction of peroxynitrite with glycerol.
The Biochemical journal 1997;328 ( Pt 2)():517-24.
1997: Dimitri A Svistunenko; Rakesh P Patel; S V Voloshchenko; Michael T Wilson
The globin-based free radical of ferryl hemoglobin is detected in normal human blood.
The Journal of biological chemistry 1997;272(11):7114-21.
1997: Rakesh P Patel; Dimitri A Svistunenko; Michael T Wilson; Victor Darley-Usmar
Reduction of Cu(II) by lipid hydroperoxides: implications for the copper-dependent oxidation of low-density lipoprotein.
The Biochemical journal 1997;322 ( Pt 2)():425-33.
1996: Rakesh P Patel; Ulf Diczfalusy; S Dzeletovic; Michael T Wilson; Victor Darley-Usmar
Formation of oxysterols during oxidation of low density lipoprotein by peroxynitrite, myoglobin, and copper.
Journal of lipid research 1996;37(11):2361-71.
1996: Rakesh P Patel; Dimitri A Svistunenko; Victor Darley-Usmar; M C Symons; Michael T Wilson
Redox cycling of human methaemoglobin by H2O2 yields persistent ferryl iron and protein based radicals.
Free radical research 1996;25(2):117-23.
1996: Dimitri A Svistunenko; Rakesh P Patel; Michael T Wilson
An EPR investigation of human methaemoglobin oxidation by hydrogen peroxide: methods to quantify all paramagnetic species observed in the reaction.
Free radical research 1996;24(4):269-80.
1996: Rakesh P Patel; Victor Darley-Usmar
Using peroxynitrite as oxidant with low-density lipoprotein.
Methods in enzymology 1996;269():375-84.
1995: M S Rogers; Rakesh P Patel; B J Reeder; P Sarti; Michael T Wilson; Abdu I Alayash
Pro-oxidant effects of cross-linked haemoglobins explored using liposome and cytochrome c oxidase vesicle model membranes.
The Biochemical journal 1995;310 ( Pt 3)():827-33.