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Bruce Patterson

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Emel Esen; Courtney M Karner; Adewole L Okunade; Bruce W Patterson; Jianquan Chen; Fanxin Long
WNT-LRP5 Signaling Induces Warburg Effect through mTORC2 Activation during Osteoblast Differentiation.
Laura Palanker Musselman; Adewole L Okunade; Bruce W Patterson; Prasanna Venkatesh Ramachandran; John Turk; Michael R Brent; Jill L Fink; Ezekiel Maier; Thomas J Baranski
Role of fat body lipogenesis in protection against the effects of caloric overload in Drosophila.
Elisa Fabbrini; Amalia Gastaldelli; Paul B Higgins; Jay D Horton; Faidon Magkos; Daniela Omodei; Bruce W Patterson; Robert E Shade; V Saroja Voruganti; Raul A Bastarrachea; Anthony G Comuzzie; Samuel Klein
Metabolic response to high-carbohydrate and low-carbohydrate meals in a nonhuman primate model.

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2013: Emel Esen; Courtney M Karner; Adewole L Okunade; Bruce W Patterson; Jianquan Chen; Fanxin Long
WNT-LRP5 Signaling Induces Warburg Effect through mTORC2 Activation during Osteoblast Differentiation.
Cell metabolism 2013;17(5):745-55.
2013: Laura Palanker Musselman; Adewole L Okunade; Bruce W Patterson; Prasanna Venkatesh Ramachandran; John Turk; Michael R Brent; Jill L Fink; Ezekiel Maier; Thomas J Baranski
Role of fat body lipogenesis in protection against the effects of caloric overload in Drosophila.
The Journal of biological chemistry 2013;288(12):8028-42.
2013: Elisa Fabbrini; Amalia Gastaldelli; Paul B Higgins; Jay D Horton; Faidon Magkos; Daniela Omodei; Bruce W Patterson; Robert E Shade; V Saroja Voruganti; Raul A Bastarrachea; Anthony G Comuzzie; Samuel Klein
Metabolic response to high-carbohydrate and low-carbohydrate meals in a nonhuman primate model.
American journal of physiology. Endocrinology and metabolism 2013;304(4):E444-51.
2012: Bernard V Miller; Adewole Okunade; Bruce W Patterson; Samuel Klein
Fatty acid and very low density lipoprotein metabolism in obese African American and Caucasian women with type 2 diabetes.
Journal of lipid research 2012;53(12):2767-72.
2012: Jun Yoshino; Caterina Conte; Luigi Fontana; Charles Gu; Shin-ichiro Imai; Iris Kunz; Bettina Mittendorfer; Bruce W Patterson; Filippo Rossi-Fanelli; Kenneth B Schechtman; Samuel Klein
Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance.
Cell metabolism 2012;16(5):658-64.
2012: Xuewen Wang; Janine Kampelman; Faidon Magkos; Bruce W Patterson; Dominic N Reeds; Bettina Mittendorfer
Low-dose dexamethasone administration for 3 weeks favorably affects plasma HDL concentration and composition but does not affect very low-density lipoprotein kinetics.
European journal of endocrinology / European Federation of Endocrine Societies 2012;167(2):217-23.
2012: Burton M Wice; Dan L Crimmins; Judit Dunai; Jack H Ladenson; Bruce W Patterson; Dominic N Reeds; Hung D Tran; Dennis T Villareal; Michael J Wallendorf; Kenneth S Polonsky
Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes.
Diabetes 2012;61(7):1793-800.
2012: Faidon Magkos; Bruce W Patterson; Caterina Conte; Elisa Fabbrini; Samuel Klein
Relationship between adipose tissue lipolytic activity and skeletal muscle insulin resistance in nondiabetic women.
The Journal of clinical endocrinology and metabolism 2012;97(7):E1219-23.
2012: Faidon Magkos; Bruce W Patterson; Xiong Su; J Esteban Varela; David Bradley; Elizabeth M Brunt; Caterina Conte; J Christopher Eagon; Elisa Fabbrini; Samuel Klein
Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects.
Gastroenterology 2012;142(7):1444-6.e2.
2012: Samuel Klein; Bruce W Patterson; Kenneth S Polonsky; Joao E Salles; Carlos A Schiavon; Bernardo L Wajchenberg; Jose L Correa; Elisa Fabbrini; Ricardo Cohen
Moderate effect of duodenal-jejunal bypass surgery on glucose homeostasis in patients with type 2 diabetes.
Obesity (Silver Spring, Md.) 2012;20(6):1266-72.
2012: Shelby Sullivan; Erik P Kirk; Bettina Mittendorfer; Bruce W Patterson; Samuel Klein
Randomized trial of exercise effect on intrahepatic triglyceride content and lipid kinetics in nonalcoholic fatty liver disease.
Hepatology (Baltimore, Md.) 2012;55(6):1738-45.
2012: Xuewen Wang; Janine Kampelman; Faidon Magkos; Bruce W Patterson; Dominic N Reeds; Gordon I Smith; Bettina Mittendorfer
Testosterone increases the muscle protein synthesis rate but does not affect very-low-density lipoprotein metabolism in obese premenopausal women.
American journal of physiology. Endocrinology and metabolism 2012;302(6):E740-6.
2012: Elisa Fabbrini; Faidon Magkos; Bettina Mittendorfer; Bruce W Patterson; Samuel Klein
Subclinical hypothyroidism and hyperthyroidism have opposite effects on hepatic very-low-density lipoprotein-triglyceride kinetics.
The Journal of clinical endocrinology and metabolism 2012;97(3):E414-8.
2012: Kristin R Wildsmith; Chengjie Xiong; Kevin E Yarasheski; Hyejin Yoon; Jacob Basak; Alison Goate; David M Holtzman; Hong Jiang; Tom Kasten; Jungsu Kim; Kwasi G Mawuenyega; Maia Parsadanian; Bruce W Patterson; Yuriy Pyatkivskyy; Wendy C Sigurdson; Jennifer X Wang; Randall Bateman
In vivo human apolipoprotein E isoform fractional turnover rates in the CNS.
PloS one 2012;7(6):e38013.
2012: Jacob Basak; Randall J Bateman; Hong Jiang; Jungsu Kim; Maia Parsadanian; Bruce W Patterson; Yuriy Pyatkivskyy; Kristin R Wildsmith; David M Holtzman
Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling.
Molecular neurodegeneration 2012;7():14.
2011: Shelby Sullivan; Elisa Fabbrini; Jay D Horton; Kevin Korenblat; Bruce W Patterson; Samuel Klein
Lack of a relationship between plasma PCSK9 concentrations and hepatic lipoprotein kinetics in obese people.
Translational research : the journal of laboratory and clinical medicine 2011;158(5):302-6.
2011: Faidon Magkos; Bruce W Patterson; J Christopher Eagon; Elisa Fabbrini; Samuel Klein
Portal vein and systemic adiponectin concentrations are closely linked with hepatic glucose and lipoprotein kinetics in extremely obese subjects.
Metabolism: clinical and experimental 2011;60(11):1641-8.
2011: Emily S Jungheim; George A Macones; Randall R Odem; Bruce W Patterson; Kelle H Moley
Elevated serum α-linolenic acid levels are associated with decreased chance of pregnancy after in vitro fertilization.
Fertility and sterility 2011;96(4):880-3.
2011: Faidon Magkos; Adewole L Okunade; Bruce W Patterson; E Fabbrini; K Korenblat; Samuel Klein
Reproducibility of glucose, fatty acid and VLDL kinetics and multi-organ insulin sensitivity in obese subjects with non-alcoholic fatty liver disease.
International journal of obesity (2005) 2011;35(9):1233-40.
2011: Joseph M Castellano; Carlos Cruchaga; Ronald B DeMattos; Anne M Fagan; Alison Goate; Hong Jiang; Jungsu Kim; Kwasi G Mawuenyega; John C Morris; Bruce W Patterson; Steven M Paul; Floy R Stewart; Kelly R Bales; Randall Bateman; David M Holtzman
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
Science translational medicine 2011;3(89):89ra57.
2011: Dominic N Reeds; Bruce W Patterson; Adewole Okunade; John O Holloszy; Kenneth S Polonsky; Samuel Klein
Ginseng and ginsenoside Re do not improve β-cell function or insulin sensitivity in overweight and obese subjects with impaired glucose tolerance or diabetes.
Diabetes care 2011;34(5):1071-6.
2011: Emily S Jungheim; George A Macones; Randall R Odem; Bruce W Patterson; Susan E Lanzendorf; Valerie S Ratts; Kelle H Moley
Associations between free fatty acids, cumulus oocyte complex morphology and ovarian function during in vitro fertilization.
Fertility and sterility 2011;95(6):1970-4.
2011: Elisa Fabbrini; Faidon Magkos; Xiong Su; Nada A Abumrad; Nicole Nejedly; Carrie C Coughlin; Adewole L Okunade; Bruce W Patterson; Samuel Klein
Insulin sensitivity is not associated with palmitoleate availability in obese humans.
Journal of lipid research 2011;52(4):808-12.
2011: Gordon I Smith; Bruce W Patterson; Bettina Mittendorfer
Human muscle protein turnover--why is it so variable?
Journal of applied physiology (Bethesda, Md. : 1985) 2011;110(2):480-91.
2010: Faidon Magkos; E Fabbrini; J McCrea; Bruce W Patterson; J Christopher Eagon; Samuel Klein
Decrease in hepatic very-low-density lipoprotein-triglyceride secretion after weight loss is inversely associated with changes in circulating leptin.
Diabetes, obesity & metabolism 2010;12(7):584-90.
2010: Faidon Magkos; Elisa Fabbrini; B Selma Mohammed; Bruce W Patterson; Samuel Klein; Bettina Mittendorfer
Estrogen deficiency after menopause does not result in male very-low-density lipoprotein metabolism phenotype.
The Journal of clinical endocrinology and metabolism 2010;95(7):3377-84.
2010: Elisa Fabbrini; B Selma Mohammed; Kevin M Korenblat; Faidon Magkos; Jennifer McCrea; Bruce W Patterson; Samuel Klein
Effect of fenofibrate and niacin on intrahepatic triglyceride content, very low-density lipoprotein kinetics, and insulin action in obese subjects with nonalcoholic fatty liver disease.
The Journal of clinical endocrinology and metabolism 2010;95(6):2727-35.
2010: Dennis T Villareal; Heather Robertson; Graeme I Bell; Bruce W Patterson; Hung Tran; Burton M Wice; Kenneth S Polonsky
TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action.
Diabetes 2010;59(2):479-85.
2009: Elisa Fabbrini; Faidon Magkos; B Selma Mohammed; Terri Pietka; Nada A Abumrad; Bruce W Patterson; Adewole Okunade; Samuel Klein
Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(36):15430-5.
2009: Faidon Magkos; B Selma Mohammed; Bruce W Patterson; Bettina Mittendorfer
Free fatty acid kinetics in the late phase of postexercise recovery: importance of resting fatty acid metabolism and exercise-induced energy deficit.
Metabolism: clinical and experimental 2009;58(9):1248-55.
2009: Dennis T Villareal; Joseph C Koster; Heather Robertson; Alejandro Akrouh; Kazuaki Miyake; Graeme I Bell; Bruce W Patterson; Colin G Nichols; Kenneth S Polonsky
Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance.
Diabetes 2009;58(8):1869-78.
2009: Erik Kirk; Dominic N Reeds; Brian N Finck; S Mitra Mayurranjan; Mitra S Mayurranjan; Bruce W Patterson; Samuel Klein
Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction.
Gastroenterology 2009;136(5):1552-60.
2009: Faidon Magkos; Bruce W Patterson; B Selma Mohammed; Bettina Mittendorfer
Basal adipose tissue and hepatic lipid kinetics are not affected by a single exercise bout of moderate duration and intensity in sedentary women.
Clinical science (London, England : 1979) 2009;116(4):327-34.
2008: Dennis T Villareal; Marian R Banks; Bruce W Patterson; Kenneth S Polonsky; Samuel Klein
Weight loss therapy improves pancreatic endocrine function in obese older adults.
Obesity (Silver Spring, Md.) 2008;16(6):1349-54.
2008: Christina Koutsari; Daniel A Dumesic; Bruce W Patterson; Susanne B Votruba; Michael D Jensen
Plasma free fatty acid storage in subcutaneous and visceral adipose tissue in postabsorptive women.
Diabetes 2008;57(5):1186-94.
2008: Elisa Fabbrini; B Selma Mohammed; Faidon Magkos; Kevin M Korenblat; Bruce W Patterson; Samuel Klein
Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease.
Gastroenterology 2008;134(2):424-31.
2007: Faidon Magkos; Bruce W Patterson; B Selma Mohammed; Bettina Mittendorfer
A single 1-h bout of evening exercise increases basal FFA flux without affecting VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics in untrained lean men.
American journal of physiology. Endocrinology and metabolism 2007;292(6):E1568-74.
2007: Faidon Magkos; Bruce W Patterson; Bettina Mittendorfer
Reproducibility of stable isotope-labeled tracer measures of VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics.
Journal of lipid research 2007;48(5):1204-11.
2007: Faidon Magkos; Bruce W Patterson; B Selma Mohammed; Samuel Klein; Bettina Mittendorfer
Women produce fewer but triglyceride-richer very low-density lipoproteins than men.
The Journal of clinical endocrinology and metabolism 2007;92(4):1311-8.
2007: W Todd Cade; Dominic N Reeds; Bettina Mittendorfer; Bruce W Patterson; William G Powderly; Samuel Klein; Kevin E Yarasheski
Blunted lipolysis and fatty acid oxidation during moderate exercise in HIV-infected subjects taking HAART.
American journal of physiology. Endocrinology and metabolism 2007;292(3):E812-9.
2006: Faidon Magkos; Bruce W Patterson; Bettina Mittendorfer
No effect of menstrual cycle phase on basal very-low-density lipoprotein triglyceride and apolipoprotein B-100 kinetics.
American journal of physiology. Endocrinology and metabolism 2006;291(6):E1243-9.
2006: Dominic N Reeds; W Todd Cade; Bruce W Patterson; William G Powderly; Samuel Klein; Kevin E Yarasheski
Whole-body proteolysis rate is elevated in HIV-associated insulin resistance.
Diabetes 2006;55(10):2849-55.
2006: Viraine Weerasooriya; Michael John Rennie; Shri Anant; David H Alpers; Bruce W Patterson; Samuel Klein
Dietary fiber decreases colonic epithelial cell proliferation and protein synthetic rates in human subjects.
American journal of physiology. Endocrinology and metabolism 2006;290(6):E1104-8.
2006: Faidon Magkos; David C Wright; Bruce W Patterson; B Selma Mohammed; Bettina Mittendorfer
Lipid metabolism response to a single, prolonged bout of endurance exercise in healthy young men.
American journal of physiology. Endocrinology and metabolism 2006;290(2):E355-62.
2006: William L Isley; John M Miles; Bruce W Patterson; William S Harris
The effect of high-dose simvastatin on triglyceride-rich lipoprotein metabolism in patients with type 2 diabetes mellitus.
Journal of lipid research 2006;47(1):193-200.
2006: Dominic N Reeds; Kevin E Yarasheski; luigi fontana; W Todd Cade; E Laciny; A DeMoss; Bruce W Patterson; William G Powderly; Samuel Klein
Alterations in liver, muscle, and adipose tissue insulin sensitivity in men with HIV infection and dyslipidemia.
American journal of physiology. Endocrinology and metabolism 2006;290(1):E47-E53.
2005: Simon W Coppack; David L Chinkes; John M Miles; Bruce W Patterson; Samuel Klein
A multicompartmental model of in vivo adipose tissue glycerol kinetics and capillary permeability in lean and obese humans.
Diabetes 2005;54(7):1934-41.
2004: Fatiha Nassir; Yan Xie; Bruce W Patterson; Jianyang Luo; Nicholas O Davidson
Hepatic secretion of small lipoprotein particles in apobec-1-/- mice is regulated by the LDL receptor.
Journal of lipid research 2004;45(9):1649-59.
2004: Samuel Klein; luigi fontana; V Leroy Young; Andrew Coggan; Charles Kilo; Bruce W Patterson; B Selma Mohammed
Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease.
The New England journal of medicine 2004;350(25):2549-57.
2003: Dominic N Reeds; Bettina Mittendorfer; Bruce W Patterson; William G Powderly; Kevin E Yarasheski; Samuel Klein
Alterations in lipid kinetics in men with HIV-dyslipidemia.
American journal of physiology. Endocrinology and metabolism 2003;285(3):E490-7.
2003: Nicholas Frank; Janice E Sojka; Bruce W Patterson; Karl V Wood; Connie C Bonham; Mickey A Latour
Effect of hypothyroidism on kinetics of metabolism of very-low-density lipoprotein in mares.
American journal of veterinary research 2003;64(8):1052-8.
2003: Bettina Mittendorfer; Olivia Liem; Bruce W Patterson; John M Miles; Samuel Klein
What does the measurement of whole-body fatty acid rate of appearance in plasma by using a fatty acid tracer really mean?
Diabetes 2003;52(7):1641-8.
2003: Bettina Mittendorfer; Bruce W Patterson; Samuel Klein; Labros S Sidossis
VLDL-triglyceride kinetics during hyperglycemia-hyperinsulinemia: effects of sex and obesity.
American journal of physiology. Endocrinology and metabolism 2003;284(4):E708-15.
2003: Bettina Mittendorfer; Bruce W Patterson; Samuel Klein
Effect of sex and obesity on basal VLDL-triacylglycerol kinetics.
The American journal of clinical nutrition 2003;77(3):573-9.
2003: Gustav Schonfeld; Bruce W Patterson; Dmitriy A Yablonskiy; Tariq S K Tanoli; Maurizio R Averna; Nizar Elias; Pin Yue; Joseph Ackerman
Fatty liver in familial hypobetalipoproteinemia: triglyceride assembly into VLDL particles is affected by the extent of hepatic steatosis.
Journal of lipid research 2003;44(3):470-8.
2003: Bettina Mittendorfer; Bruce W Patterson; Samuel Klein
Effect of weight loss on VLDL-triglyceride and apoB-100 kinetics in women with abdominal obesity.
American journal of physiology. Endocrinology and metabolism 2003;284(3):E549-56.
2002: Bruce W Patterson
Methods for measuring lipid metabolism in vivo.
Current opinion in clinical nutrition and metabolic care 2002;5(5):475-9.
2002: Bruce W Patterson; Jeffrey F Horowitz; Guoyao Wu; Malcolm Watford; Simon W Coppack; Samuel Klein
Regional muscle and adipose tissue amino acid metabolism in lean and obese women.
American journal of physiology. Endocrinology and metabolism 2002;282(4):E931-6.
2002: Bruce W Patterson; Bettina Mittendorfer; Nizar Elias; Raj Satyanarayana; Samuel Klein
Use of stable isotopically labeled tracers to measure very low density lipoprotein-triglyceride turnover.
Journal of lipid research 2002;43(2):223-33.
2001: Bettina Mittendorfer; Richard E Ostlund; Bruce W Patterson; Samuel Klein
Orlistat inhibits dietary cholesterol absorption.
Obesity research 2001;9(10):599-604.
2000: Nizar Elias; Bruce W Patterson; Gustav Schonfeld
In vivo metabolism of ApoB, ApoA-I, and VLDL triglycerides in a form of hypobetalipoproteinemia not linked to the ApoB gene.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(5):1309-15.
1999: Nizar Elias; Bruce W Patterson; Gustav Schonfeld
Decreased production rates of VLDL triglycerides and ApoB-100 in subjects heterozygous for familial hypobetalipoproteinemia.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(11):2714-21.
1999: Bruce W Patterson; G Zhao; Nizar Elias; D L Hachey; Samuel Klein
Validation of a new procedure to determine plasma fatty acid concentration and isotopic enrichment.
Journal of lipid research 1999;40(11):2118-24.
1999: Mickey A Latour; Bruce W Patterson; R T Kitchens; Richard E Ostlund; D Hopkins; Gustav Schonfeld
Effects of alcohol and cholesterol feeding on lipoprotein metabolism and cholesterol absorption in rabbits.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(3):598-604.
1998: Bruce W Patterson; G Zhao; Samuel Klein
Improved accuracy and precision of gas chromatography/mass spectrometry measurements for metabolic tracers.
Metabolism: clinical and experimental 1998;47(6):706-12.
1997: Mickey A Latour; Bruce W Patterson; JI Pulai; Z Chen; Gustav Schonfeld
Metabolism of apolipoprotein B-100 in a kindred with familial hypobetalipoproteinemia without a truncated form of apoB.
Journal of lipid research 1997;38(3):592-9.
1997: Bruce W Patterson
Use of stable isotopically labeled tracers for studies of metabolic kinetics: an overview.
Metabolism: clinical and experimental 1997;46(3):322-9.
1996: N Srivastava; Davide Noto; Maurizio R Averna; JI Pulai; Rai Ajit Srivastava; T G Cole; Mickey A Latour; Bruce W Patterson; Gustav Schonfeld
A new apolipoprotein B truncation (apo B-43.7) in familial hypobetalipoproteinemia: genetic and metabolic studies.
Metabolism: clinical and experimental 1996;45(10):1296-304.
1992: Bruce W Patterson; William W Wong; H P Sheng; Harry J Mersmann; W Insull; PD Klein; Marta L Fiorotto; WG Pond
Neonatal genetically lean and obese pigs respond differently to dietary cholesterol.
The Journal of nutrition 1992;122(9):1830-9.
1992: Peter J Reeds; D L Hachey; Bruce W Patterson; Kathleen J Motil; PD Klein
VLDL apolipoprotein B-100, a potential indicator of the isotopic labeling of the hepatic protein synthetic precursor pool in humans: studies with multiple stable isotopically labeled amino acids.
The Journal of nutrition 1992;122(3):457-66.
1991: Bruce W Patterson; D L Hachey; G L Cook; J M Amann; PD Klein
Incorporation of a stable isotopically labeled amino acid into multiple human apolipoproteins.
Journal of lipid research 1991;32(7):1063-72.
1991: D L Hachey; Bruce W Patterson; Peter J Reeds; Louis J Elsas
Isotopic determination of organic keto acid pentafluorobenzyl esters in biological fluids by negative chemical ionization gas chromatography/mass spectrometry.
Analytical chemistry 1991;63(9):919-23.