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Vincenzo Pavone

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Marina Faiella; Wilfred R Hagen; Liliana Lista; Angela Lombardi; Ornella Maglio; Flavia Nastri; Vincenzo Pavone
De novo design, synthesis and characterisation of MP3, a new catalytic four-helix bundle hemeprotein.
Flavia Nastri; Liliana Lista; Paola Ringhieri; Rosa Vitale; Marina Faiella; Concetta Andreozzi; Paola Travascio; Ornella Maglio; Angela Lombardi; Vincenzo Pavone
A heme-peptide metalloenzyme mimetic with natural peroxidase-like activity.
Paolo Lusso; Luca Vangelista; Raffaello Cimbro; Massimiliano Secchi; Francesca Sironi; Renato Longhi; Marina Faiella; Ornella Maglio; Vincenzo Pavone
Molecular engineering of RANTES peptide mimetics with potent anti-HIV-1 activity.

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All Publications

2012: Marina Faiella; Wilfred R Hagen; Liliana Lista; Angela Lombardi; Ornella Maglio; Flavia Nastri; Vincenzo Pavone
De novo design, synthesis and characterisation of MP3, a new catalytic four-helix bundle hemeprotein.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(50):15960-71.
2011: Flavia Nastri; Liliana Lista; Paola Ringhieri; Rosa Vitale; Marina Faiella; Concetta Andreozzi; Paola Travascio; Ornella Maglio; Angela Lombardi; Vincenzo Pavone
A heme-peptide metalloenzyme mimetic with natural peroxidase-like activity.
Chemistry (Weinheim an der Bergstrasse, Germany) 2011;17(16):4444-53.
2011: Paolo Lusso; Luca Vangelista; Raffaello Cimbro; Massimiliano Secchi; Francesca Sironi; Renato Longhi; Marina Faiella; Ornella Maglio; Vincenzo Pavone
Molecular engineering of RANTES peptide mimetics with potent anti-HIV-1 activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(4):1230-43.
2010: Rafael Torres Martin de Rosales; Marina Faiella; Erik Farquhar; Lawrence Que; Concetta Andreozzi; Vincenzo Pavone; Ornella Maglio; Flavia Nastri; Angela Lombardi
Spectroscopic and metal-binding properties of DF3: an artificial protein able to accommodate different metal ions.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2010;15(5):717-28.
2009: Marina Faiella; Concetta Andreozzi; Rafael Torres Martin de Rosales; Vincenzo Pavone; Ornella Maglio; Flavia Nastri; William F DeGrado; Angela Lombardi
An artificial di-iron oxo-protein with phenol oxidase activity.
Nature chemical biology 2009;5(12):882-4.
2005: Ornella Maglio; Flavia Nastri; Jennifer R Calhoun; Stephen Lahr; HERSCHEL WADE; Vincenzo Pavone; William F DeGrado; Angela Lombardi
Artificial di-iron proteins: solution characterization of four helix bundles containing two distinct types of inter-helical loops.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2005;10(5):539-49.
2005: Jennifer R Calhoun; Flavia Nastri; Ornella Maglio; Vincenzo Pavone; Angela Lombardi; William F DeGrado
Artificial diiron proteins: from structure to function.
Biopolymers 2005;80(2-3):264-78.
2004: Luigi Di Costanzo; Silvano Geremia; Lucio Randaccio; Flavia Nastri; Ornella Maglio; Angela Lombardi; Vincenzo Pavone
Miniaturized heme proteins: crystal structure of Co(III)-mimochrome IV.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2004;9(8):1017-27.
2003: Angela Lombardi; Flavia Nastri; Daniela Marasco; Ornella Maglio; Giampiero De Sanctis; Federica Sinibaldi; Roberto Santucci; Massimo Coletta; Vincenzo Pavone
Design of a new mimochrome with unique topology.
Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(22):5643-54.
2003: Ornella Maglio; Flavia Nastri; Vincenzo Pavone; Angela Lombardi; William F DeGrado
Preorganization of molecular binding sites in designed diiron proteins.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):3772-7.
2003: William F DeGrado; Luigi Di Costanzo; Silvano Geremia; Angela Lombardi; Vincenzo Pavone; Lucio Randaccio
Sliding helix and change of coordination geometry in a model di-MnII protein.
Angewandte Chemie (International ed. in English) 2003;42(4):417-20.
2001: Luigi Di Costanzo; HERSCHEL WADE; Silvano Geremia; Lucio Randaccio; Vincenzo Pavone; William F DeGrado; Angela Lombardi
Toward the de novo design of a catalytically active helix bundle: a substrate-accessible carboxylate-bridged dinuclear metal center.
Journal of the American Chemical Society 2001;123(51):12749-57.
2001: Angela Lombardi; Flavia Nastri; Vincenzo Pavone
Peptide-based heme-protein models.
Chemical reviews 2001;101(10):3165-89.
2000: Angela Lombardi; Daniela Marasco; Ornella Maglio; Luigi Di Costanzo; Flavia Nastri; Vincenzo Pavone
Miniaturized metalloproteins: application to iron-sulfur proteins.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(22):11922-7.
2000: Angela Lombardi; C M Summa; Silvano Geremia; Lucio Randaccio; Vincenzo Pavone; William F DeGrado
Retrostructural analysis of metalloproteins: application to the design of a minimal model for diiron proteins.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6298-305.
2000: Giuseppina De simone; Angela Lombardi; stefania galdiero; Flavia Nastri; Luigi Di Costanzo; S Gohda; A Sano; T Yamada; Vincenzo Pavone
The crystal structure of a Dcp-containing peptide.
Biopolymers 2000;53(2):182-8.
2000: Vincenzo Pavone; Angela Lombardi; Michele Saviano; Giuseppina De simone; Flavia Nastri; Ornella Maglio; Y Omote; Y Yamanaka; T Yamada
Conformational behavior of C alpha,alpha-diphenyl glycine: extended conformation in tripeptides containing consecutive D phi G residues.
Biopolymers 2000;53(2):161-8.
2000: Angela Lombardi; Giuseppina De simone; stefania galdiero; Flavia Nastri; Luigi Di Costanzo; K Makihira; T Yamada; Vincenzo Pavone
The crystal structure of Afc-containing peptides.
Biopolymers 2000;53(2):150-60.
1999: Giuseppina De simone; Giuseppe Manco; stefania galdiero; Angela Lombardi; Mosè Rossi; Vincenzo Pavone
Crystallization and preliminary X-ray diffraction studies of the carboxylesterase EST2 from Alicyclobacillus acidocaldarius.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 7):1348-9.
1999: William F DeGrado; C M Summa; Vincenzo Pavone; Flavia Nastri; Angela Lombardi
De novo design and structural characterization of proteins and metalloproteins.
Annual review of biochemistry 1999;68():779-819.
1999: Angela Lombardi; Giuseppina De simone; stefania galdiero; Norma Staiano; Flavia Nastri; Vincenzo Pavone
From natural to synthetic multisite thrombin inhibitors.
Biopolymers 1999;51(1):19-39.
1999: Angela Lombardi; Giuseppina De simone; Flavia Nastri; stefania galdiero; Rossella Della Morte; Norma Staiano; Carlo Pedone; M Bolognesi; Vincenzo Pavone
The crystal structure of alpha-thrombin-hirunorm IV complex reveals a novel specificity site recognition mode.
Protein science : a publication of the Protein Society 1999;8(1):91-5.
1998: Vincenzo Pavone; Giuseppina De simone; Flavia Nastri; stefania galdiero; Norma Staiano; Angela Lombardi; Carlo Pedone
Multiple binding mode of reversible synthetic thrombin inhibitors. A comparative structural analysis.
Biological chemistry 1998;379(8-9):987-1006.
1998: Angela Lombardi; Bruno D'Agostino; Amelia Filippelli; Carlo Pedone; Maria Gabriella Matera; M Falciani; M De Rosa; Francesca Rossi; Vincenzo Pavone
Neuronorm is a potent and water soluble neurokinin A receptor antagonist.
Bioorganic & medicinal chemistry letters 1998;8(13):1735-40.
1998: Angela Lombardi; Bruno D'Agostino; Flavia Nastri; Luigi D'Andrea; Amelia Filippelli; M Falciani; Francesca Rossi; Vincenzo Pavone
A novel super-potent neurokinin A receptor antagonist containing dehydroalanine.
Bioorganic & medicinal chemistry letters 1998;8(10):1153-6.
1998: Vincenzo Pavone; Angela Lombardi; Michele Saviano; Flavia Nastri; Laura Zaccaro; Ornella Maglio; Carlo Pedone; Y Omote; Y Yamanaka; T Yamada
Conformational behaviour of C(alpha,alpha)-diphenylglycine: folded vs. extended structures in DphiG-containing tripeptides.
Journal of peptide science : an official publication of the European Peptide Society 1998;4(1):21-32.
1998: Giuseppina De simone; Angela Lombardi; stefania galdiero; Flavia Nastri; Rossella Della Morte; Norma Staiano; Carlo Pedone; M Bolognesi; Vincenzo Pavone
Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex.
Protein science : a publication of the Protein Society 1998;7(2):243-53.
1998: Flavia Nastri; Angela Lombardi; Luigi D'Andrea; Marina Sanseverino; Ornella Maglio; Vincenzo Pavone
Miniaturized hemoproteins.
Biopolymers 1998;47(1):5-22.
1996: Vincenzo Pavone; G Gaeta; Angela Lombardi; Flavia Nastri; Ornella Maglio; C Isernia; Michele Saviano
Discovering protein secondary structures: classification and description of isolated alpha-turns.
Biopolymers 1996;38(6):705-21.
1996: Angela Lombardi; Michele Saviano; Flavia Nastri; Ornella Maglio; M Mazzeo; C Isernia; Livio Paolillo; Vincenzo Pavone
Solvent-mediated conformational transition in beta-alanine containing cyclic peptides. VIII.
Biopolymers 1996;38(6):693-703.
1996: Angela Lombardi; Michele Saviano; Flavia Nastri; Ornella Maglio; M Mazzeo; Carlo Pedone; C Isernia; Vincenzo Pavone
Unusual conformational preferences of beta-alanine containing cyclic peptides. VII.
Biopolymers 1996;38(6):683-91.
1996: Angela Lombardi; Flavia Nastri; Rossella Della Morte; A Rossi; A De Rosa; Norma Staiano; Carlo Pedone; Vincenzo Pavone
Rational design of true hirudin mimetics: synthesis and characterization of multisite-directed alpha-thrombin inhibitors.
Journal of medicinal chemistry 1996;39(10):2008-17.
1996: Angela Lombardi; G D'Auria; Michele Saviano; Ornella Maglio; Flavia Nastri; L Quartara; Carlo Pedone; Vincenzo Pavone
Bicyclic peptides as type I/type II beta-turn scaffolds.
Biopolymers 1996;40(5):505-18.
1995: M Mazzeo; C Isernia; F Rossi; Michele Saviano; Carlo Pedone; Livio Paolillo; Ettore Benedetti; Vincenzo Pavone
Conformational behaviour of a cyclolinopeptide A analogue: two-dimensional NMR study of cyclo(Pro1-Pro-Phe-Phe-Ac6c-Ile-ala-Val8).
Journal of peptide science : an official publication of the European Peptide Society 1995;1(5):330-40.
1995: P Gallo; Michele Saviano; F Rossi; Vincenzo Pavone; Carlo Pedone; Raffaele Ragone; Paola Stiuso; Giovanni Colonna
Specific interaction between cyclophilin and cyclic peptides.
Biopolymers 1995;36(3):273-81.
1995: Vincenzo Pavone; A Lombardi; C A Maggi; L Quartara; Carlo Pedone
Conformational rigidity versus flexibility in a novel peptidic neurokinin A receptor antagonist.
Journal of peptide science : an official publication of the European Peptide Society 1995;1(4):236-40.
1995: R Fattorusso; G Morelli; Angela Lombardi; Flavia Nastri; Ornella Maglio; G D'Auria; Carlo Pedone; Vincenzo Pavone
Design of metal ion binding peptides.
Biopolymers 1995;37(6):401-10.
1994: Vincenzo Pavone; Angela Lombardi; Michele Saviano; Benedetto Di Blasio; Flavia Nastri; R Fattorusso; L Zaccaro; Ornella Maglio; T Yamada; Y Omote
Mixed conformation in C alpha, alpha-disubstituted tripeptides: x-ray crystal structures of Z-Aib-Dph-Gly-OMe and Bz-Dph-Dph-Gly-OMe.
Biopolymers 1994;34(12):1595-604.
1994: Vincenzo Pavone; Angela Lombardi; Michele Saviano; Flavia Nastri; R Fattorusso; Ornella Maglio; C Isernia; Livio Paolillo; Carlo Pedone
Beta-alanine containing cyclic peptides with turned structure: the "pseudo type II beta-turn." VI.
Biopolymers 1994;34(11):1517-26.
1994: Vincenzo Pavone; Angela Lombardi; Michele Saviano; Benedetto Di Blasio; Flavia Nastri; R Fattorusso; Ornella Maglio; C Isernia
Beta-alanine containing cyclic peptides with predetermined turned structure. V.
Biopolymers 1994;34(11):1505-15.
1994: Ettore Benedetti; Carlo Pedone; Vincenzo Pavone; Benedetto Di Blasio; Michele Saviano; R Fattorusso; Marco Crisma; Fernando Formaggio; G M Bonora; Claudio Toniolo
Defect peptide chemistry: perturbations in the structure of a homopentapeptide induced by a guest residue interrupting side-chain regularity.
Biopolymers 1994;34(10):1409-18.
1994: Benedetto Di Blasio; Vincenzo Pavone; Michele Saviano; R Fattorusso; Carlo Pedone; Ettore Benedetti; Marco Crisma; Claudio Toniolo
A second polymorph of a helical decapeptide.
Peptide research 1994;7(2):55-9.
1993: N Fabiano; G Valle; Marco Crisma; Claudio Toniolo; Michele Saviano; Angela Lombardi; C Isernia; Vincenzo Pavone; Benedetto Di Blasio; Carlo Pedone
Conformational versatility of the N alpha-acylated tripeptide amide tail of oxytocin. Synthesis and crystallographic characterization of three C2 alpha-backbone modified, conformationally restricted analogues.
International journal of peptide and protein research 1993;42(5):459-65.
1993: Benedetto Di Blasio; Vincenzo Pavone; Angela Lombardi; Carlo Pedone; Ettore Benedetti
Noncoded residues as building blocks in the design of specific secondary structures: symmetrically disubstituted glycines and beta-alanine.
Biopolymers 1993;33(7):1037-49.
1993: Benedetto Di Blasio; Angela Lombardi; G D'Auria; Michele Saviano; C Isernia; Ornella Maglio; Livio Paolillo; Carlo Pedone; Vincenzo Pavone
beta-Alanine containing peptides: gamma-turns in cyclotetrapeptides.
Biopolymers 1993;33(4):621-31.
1993: Vincenzo Pavone; Benedetto Di Blasio; Angela Lombardi; Ornella Maglio; C Isernia; Carlo Pedone; Ettore Benedetti; E Altmann; Manfred Mutter
Non coded C alpha, alpha-disubstituted amino acids. X-ray diffraction analysis of a dipeptide containing (S)-alpha-methylserine.
International journal of peptide and protein research 1993;41(1):15-20.
1992: Benedetto Di Blasio; Angela Lombardi; Flavia Nastri; Michele Saviano; Carlo Pedone; T Yamada; M Nakao; S Kuwata; Vincenzo Pavone
Conformation of diastereomeric peptide sequences: structural analysis of Z-D-Val-Ac6c-Gly-L-Phe-OMe.
Biopolymers 1992;32(9):1155-61.
1992: Benedetto Di Blasio; Vincenzo Pavone; Flavia Nastri; C Isernia; Michele Saviano; Carlo Pedone; V Cucinotta; G Impellizzeri; Enrico Rizzarelli; Graziella Vecchio
Conformation for a beta-cyclodextrin monosubstituted with a cyclic dipeptide.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):7218-21.
1992: Ettore Benedetti; Benedetto Di Blasio; Vincenzo Pavone; Carlo Pedone; Claudio Toniolo; Marco Crisma
Characterization at atomic resolution of peptide helical structures.
Biopolymers 1992;32(4):453-6.
1992: Vincenzo Pavone; Angela Lombardi; G D'Auria; Michele Saviano; Flavia Nastri; Livio Paolillo; Benedetto Di Blasio; Carlo Pedone
Beta-alanine containing peptides: a novel molecular tool for the design of gamma-turns.
Biopolymers 1992;32(2):173-83.
1991: Benedetto Di Blasio; Angela Lombardi; X Yang; Carlo Pedone; Vincenzo Pavone
beta-Alanyl-beta-alanine in cyclic beta-turned peptides.
Biopolymers 1991;31(10):1181-8.
1990: Vincenzo Pavone; Benedetto Di Blasio; A Santini; Ettore Benedetti; Carlo Pedone; Claudio Toniolo; Marco Crisma
The longest, regular polypeptide 3(10) helix at atomic resolution.
Journal of molecular biology 1990;214(3):633-5.
1990: Vincenzo Pavone; Ettore Benedetti; Benedetto Di Blasio; Carlo Pedone; A Santini; Alfonso Bavoso; Claudio Toniolo; Marco Crisma; L Sartore
Critical main-chain length for conformational conversion from 3(10)-helix to alpha-helix in polypeptides.
Journal of biomolecular structure & dynamics 1990;7(6):1321-31.
1990: M Grimaldi; F Rossi; Michele Saviano; Ettore Benedetti; Vincenzo Pavone; Carlo Pedone
Stereochemical behavior of acyclic peptide-cation complexes.
Biopolymers 1990;30(1-2):197-204.
1989: Ettore Benedetti; Benedetto Di Blasio; Vincenzo Pavone; Carlo Pedone; A Santini; V Barone; Franca Fraternali; F Lelj; Alfonso Bavoso; Marco Crisma
Structural versatility of peptides containing C alpha, alpha-dialkylated glycines. An X-ray diffraction study of six 1-aminocyclopropane-1-carboxylic acid rich peptides.
International journal of biological macromolecules 1989;11(6):353-60.
1989: Marco Crisma; G M Bonora; Claudio Toniolo; V Barone; Ettore Benedetti; Benedetto Di Blasio; Vincenzo Pavone; Carlo Pedone; A Santini; Franca Fraternali
Structural versatility of peptides containing C alpha, alpha-dialkylated glycines: conformational energy computations, i.r. absorption and 1H n.m.r. analysis of 1-aminocyclopropane-1-carboxylic acid homopeptides.
International journal of biological macromolecules 1989;11(6):345-52.
1988: Alfonso Bavoso; Ettore Benedetti; Benedetto Di Blasio; Vincenzo Pavone; Carlo Pedone; Claudio Toniolo; G M Bonora; Fernando Formaggio; M Crisman
Long, chiral polypeptide 3(10)-helices at atomic resolution.
Journal of biomolecular structure & dynamics 1988;5(4):803-17.
1985: Claudio Toniolo; G M Bonora; Alfonso Bavoso; Ettore Benedetti; Benedetto Di Blasio; Vincenzo Pavone; Carlo Pedone
Molecular structure of peptaibol antibiotics: solution conformation and crystal structure of the octapeptide corresponding to the 2-9 sequence of emerimicins III and IV.
Journal of biomolecular structure & dynamics 1985;3(3):585-98.
1983: Claudio Toniolo; G M Bonora; Marco Crisma; Ettore Benedetti; Alfonso Bavoso; Benedetto Di Blasio; Vincenzo Pavone; Carlo Pedone
Bioorganic stereochemistry. A study of the peptide oxazolones from Z-(Aib)n-OH (n = 2-4) in the solid state.
International journal of peptide and protein research 1983;22(5):603-10.
1983: Ettore Benedetti; Alfonso Bavoso; Benedetto Di Blasio; Vincenzo Pavone; Carlo Pedone; Claudio Toniolo; G M Bonora; Marco Crisma
Protected 1-3 segment of the peptaibol antibiotics alamethicin and hypelcin. Solid-state and solution study of a stereochemically constrained linear peptide.
International journal of peptide and protein research 1983;22(4):385-97.
1982: Ettore Benedetti; Alfonso Bavoso; Benedetto Di Blasio; Vincenzo Pavone; Carlo Pedone; Claudio Toniolo; G M Bonora
Peptaibol antibiotics: a study on the helical structure of the 2-9 sequence of emerimicins III and IV.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(24):7951-4.
1982: Ettore Benedetti; Alfonso Bavoso; Benedetto Di Blasio; Vincenzo Pavone; Carlo Pedone; Claudio Toniolo; G M Bonora
Conformation of linear homo-oligoprolines. VII. N-pivaloyl-L-prolyl-D-proline methyl ester in the solid state.
International journal of peptide and protein research 1982;20(4):312-9.