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Robert Pawliuk

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

Procedures

Physiology

Transduction, Genetic

Devices

Gene Transfer Techniques

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Publications

TOP 3
Allison Vitsky; James Waire; Robert Pawliuk; Arden Bond; Douglas Matthews; Emily Lacasse; Michael L Hawes; Carol Nelson; Susan Richards; Peter A Piepenhagen; Richard D Garman; Laura Andrews; Beth L Thurberg; Scott Lonning; Steve Ledbetter; Melanie C Ruzek
Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues.
Jia-Lin Zhang; Jin Cai; Shannon Walls; John D Jackson; Charles A Kuszynski; Yong Zhao; Robert Pawliuk; Philippe Leboulch; Ira J Fox
Tolerance by selective in vivo expansion of foreign major histocompatibility complex-transduced autologous bone marrow.
Bruno Dalle; Joel E Rubin; Ozan Alkan; Tanya Sukonnik; Peter Pasceri; Shuyuan Yao; Robert Pawliuk; Philippe Leboulch; James Ellis
eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides.

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All Publications

2009: Allison Vitsky; James Waire; Robert Pawliuk; Arden Bond; Douglas Matthews; Emily Lacasse; Michael L Hawes; Carol Nelson; Susan Richards; Peter A Piepenhagen; Richard D Garman; Laura Andrews; Beth L Thurberg; Scott Lonning; Steve Ledbetter; Melanie C Ruzek
Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues.
The American journal of pathology 2009;174(6):2137-49.
2005: Jia-Lin Zhang; Jin Cai; Shannon Walls; John D Jackson; Charles A Kuszynski; Yong Zhao; Robert Pawliuk; Philippe Leboulch; Ira J Fox
Tolerance by selective in vivo expansion of foreign major histocompatibility complex-transduced autologous bone marrow.
Transplantation 2005;80(3):362-9.
2005: Bruno Dalle; Joel E Rubin; Ozan Alkan; Tanya Sukonnik; Peter Pasceri; Shuyuan Yao; Robert Pawliuk; Philippe Leboulch; James Ellis
eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(4):591-9.
2005: Robert Pawliuk; robert Tighe; Robert J Wise; Micheline M Mathews-Roth; Philippe Leboulch
Prevention of murine erythropoietic protoporphyria-associated skin photosensitivity and liver disease by dermal and hepatic ferrochelatase.
The Journal of investigative dermatology 2005;124(1):256-62.
2004: Suzan Imren; Mary E Fabry; Karen A Westerman; Robert Pawliuk; Patrick Tang; Patricia M Rosten; Ronald L Nagel; Philippe Leboulch; Connie J Eaves; R Keith Humphries
High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells.
The Journal of clinical investigation 2004;114(7):953-62.
2004: Il-Hoan Oh; Mary E Fabry; R Keith Humphries; Robert Pawliuk; Philippe Leboulch; Ronald Hoffman; Ronald L Nagel; Connie Eaves
Expression of an anti-sickling beta-globin in human erythroblasts derived from retrovirally transduced primitive normal and sickle cell disease hematopoietic cells.
Experimental hematology 2004;32(5):461-9.
2004: Daniela Geromin; Jean-François Bourge; Annie Soulié; Robert Pawliuk; Christina Fleet; Eugene Michel; Yves Denizot; Christian Berthou; Philippe Leboulch; François Sigaux; Marilyne Sasportes
Glycoprotein 170 induces platelet-activating factor receptor membrane expression and confers tumor cell hypersensitivity to NK-dependent cell lysis.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(6):3604-11.
2003: Renhai Cao; Ebba Brakenhielm; Robert Pawliuk; David Wariaro; Mark J Post; eric wahlberg; Philippe Leboulch; Yihai Cao
Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2.
Nature medicine 2003;9(5):604-13.
2003: Elvire Gouze; Robert Pawliuk; Jean-Noel Gouze; Carmencita Pilapil; Christina Fleet; Glyn D Palmer; Christopher H Evans; Philippe Leboulch; Steven C Ghivizzani
Lentiviral-mediated gene delivery to synovium: potent intra-articular expression with amplification by inflammation.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(4):460-6.
2002: Suzan Imren; Emmanuel Payen; Karen A Westerman; Robert Pawliuk; Mary E Fabry; Connie J Eaves; Benjamin Cavilla; Louis D Wadsworth; Yves Beuzard; Eric E Bouhassira; Robert Russell; Irving M London; Ronald L Nagel; Philippe Leboulch; R Keith Humphries
Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):14380-5.
2002: Elvire Gouze; Robert Pawliuk; Carmencita Pilapil; Jean-Noel Gouze; Christina Fleet; Glyn D Palmer; Christopher H Evans; Philippe Leboulch; Steven C Ghivizzani
In vivo gene delivery to synovium by lentiviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(4):397-404.
2002: Wolfgang Eisterer; Xiaoyan Jiang; Thomas Bachelot; Robert Pawliuk; Carolina Abramovich; Philippe Leboulch; Donna E Hogge; Connie Eaves
Unfulfilled promise of endostatin in a gene therapy-xenotransplant model of human acute lymphocytic leukemia.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(4):352-9.
2002: Robert Pawliuk; Thomas Bachelot; Omar Zurkiya; Anna Eriksson; Yihai Cao; Philippe Leboulch
Continuous intravascular secretion of endostatin in mice from transduced hematopoietic stem cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(4):345-51.
2002: Anna Eriksson; Renhai Cao; Robert Pawliuk; Sanna Maria Berg; Monica Tsang; Danielle Zhou; Christina Fleet; Katerina Tritsaris; Steen Dissing; Philippe Leboulch; Yihai Cao
Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers.
Cancer cell 2002;1(1):99-108.
2001: Robert Pawliuk; Karen A Westerman; Mary E Fabry; Emmanuel Payen; robert Tighe; Eric E Bouhassira; Seetharama A Acharya; James Ellis; Irving M London; Connie J Eaves; R Keith Humphries; Yves Beuzard; Ronald L Nagel; Philippe Leboulch
Correction of sickle cell disease in transgenic mouse models by gene therapy.
Science (New York, N.Y.) 2001;294(5550):2368-71.
2000: Christian Kalberer; Robert Pawliuk; Suzan Imren; Thomas Bachelot; K J Takekoshi; Mary E Fabry; Connie J Eaves; Irving M London; R Keith Humphries; Philippe Leboulch
Preselection of retrovirally transduced bone marrow avoids subsequent stem cell gene silencing and age-dependent extinction of expression of human beta-globin in engrafted mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5411-5.
1999: C C Lai; Peter Gouras; Kentaro Doi; F Lu; Hild Kjeldbye; Stephen P Goff; Robert Pawliuk; Philippe Leboulch; Stephen H Tsang
Tracking RPE transplants labeled by retroviral gene transfer with green fluorescent protein.
Investigative ophthalmology & visual science 1999;40(9):2141-6.
1999: Robert Pawliuk; Thomas Bachelot; R J Wise; Micheline M Mathews-Roth; Philippe Leboulch
Long-term cure of the photosensitivity of murine erythropoietic protoporphyria by preselective gene therapy.
Nature medicine 1999;5(7):768-73.
1999: B Hennemann; Eibhlin Conneally; Robert Pawliuk; Philippe Leboulch; S Rose-John; D Reid; Jean Y Chuo; R Keith Humphries; Connie J Eaves
Optimization of retroviral-mediated gene transfer to human NOD/SCID mouse repopulating cord blood cells through a systematic analysis of protocol variables.
Experimental hematology 1999;27(5):817-25.
1998: Robert Pawliuk; Thomas Bachelot; Harry Raftopoulos; Christian Kalberer; R Keith Humphries; Arthur Bank; Philippe Leboulch
Retroviral vectors aimed at the gene therapy of human beta-globin gene disorders.
Annals of the New York Academy of Sciences 1998;850():151-62.
1997: Robert Pawliuk; Connie J Eaves; R Keith Humphries
Sustained high-level reconstitution of the hematopoietic system by preselected hematopoietic cells expressing a transduced cell-surface antigen.
Human gene therapy 1997;8(13):1595-604.
1996: Robert Pawliuk; C Eaves; R Keith Humphries
Evidence of both ontogeny and transplant dose-regulated expansion of hematopoietic stem cells in vivo.
Blood 1996;88(8):2852-8.
1996: Jeffrey A Medin; M Migita; Robert Pawliuk; Steven Jacobson; M Amiri; S Kluepfel-Stahl; Roscoe O Brady; R Keith Humphries; S Karlsson
A bicistronic therapeutic retroviral vector enables sorting of transduced CD34+ cells and corrects the enzyme deficiency in cells from Gaucher patients.
Blood 1996;87(5):1754-62.
1995: M Migita; Jeffrey A Medin; Robert Pawliuk; Steven Jacobson; James W Nagle; S Anderson; M Amiri; R Keith Humphries; S Karlsson
Selection of transduced CD34+ progenitors and enzymatic correction of cells from Gaucher patients, with bicistronic vectors.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12075-9.
1994: Robert Pawliuk; R Kay; Peter M Lansdorp; R Keith Humphries
Selection of retrovirally transduced hematopoietic cells using CD24 as a marker of gene transfer.
Blood 1994;84(9):2868-77.