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Oluf Pedersen

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Bonnefond Amélie; Vaxillaire Martine; Labrune Yann; Lecoeur Cécile; Chèvre Jean-Claude; Bouatia-Naji Nabila; Cauchi Stéphane; Balkau Beverley; Marre Michel; Tichet Jean; Riveline Jean-Pierre; Hadjadj Samy; Gallois Yves; Czernichow Sébastien; Hercberg Serge; Kaakinen Marika; Wiesner Susanne; Charpentier Guillaume; Lévy-Marchal Claire; Elliott Paul; Jarvelin Marjo-Riitta; Horber Fritz; Dina Christian; Pedersen Oluf; Sladek Robert; Meyre David; Froguel Philippe
Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits.
Rose C S; Grarup N; Krarup N T; Poulsen P; Wegner L; Nielsen T; Banasik K; Faerch K; Andersen G; Albrechtsen A; Borch-Johnsen K; Clausen J O; Jørgensen T; Vaag A; Pedersen O; Hansen T
A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads.
Grunnet Louise G; Nilsson Emma; Ling Charlotte; Hansen Torben; Pedersen Oluf; Groop Leif; Vaag Allan; Poulsen Pernille
Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue.

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All Publications

2009: Bonnefond Amélie; Vaxillaire Martine; Labrune Yann; Lecoeur Cécile; Chèvre Jean-Claude; Bouatia-Naji Nabila; Cauchi Stéphane; Balkau Beverley; Marre Michel; Tichet Jean; Riveline Jean-Pierre; Hadjadj Samy; Gallois Yves; Czernichow Sébastien; Hercberg Serge; Kaakinen Marika; Wiesner Susanne; Charpentier Guillaume; Lévy-Marchal Claire; Elliott Paul; Jarvelin Marjo-Riitta; Horber Fritz; Dina Christian; Pedersen Oluf; Sladek Robert; Meyre David; Froguel Philippe
Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits.
Diabetes 2009;58(11):2687-97.
2009: Rose C S; Grarup N; Krarup N T; Poulsen P; Wegner L; Nielsen T; Banasik K; Faerch K; Andersen G; Albrechtsen A; Borch-Johnsen K; Clausen J O; Jørgensen T; Vaag A; Pedersen O; Hansen T
A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads.
Diabetologia 2009;52(10):2122-9.
2009: Grunnet Louise G; Nilsson Emma; Ling Charlotte; Hansen Torben; Pedersen Oluf; Groop Leif; Vaag Allan; Poulsen Pernille
Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue.
Diabetes 2009;58(10):2402-8.
2009: Boesgaard T W; Nielsen T T; Josefsen K; Hansen T; Jørgensen T; Pedersen O; Nørremølle A; Nielsen J E; Hasholt L
Huntington's disease does not appear to increase the risk of diabetes mellitus.
Journal of neuroendocrinology 2009;21(9):770-6.
2009: Koutnikova Hana; Laakso Markku; Lu Lu; Combe Roy; Paananen Jussi; Kuulasmaa Teemu; Kuusisto Johanna; Häring Hans-Ulrich; Hansen Torben; Pedersen Oluf; Smith Ulf; Hanefeld Markolf; Williams Robert W; Auwerx Johan
Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.
PLoS genetics 2009;5(8):e1000591.
2009: Reiling Erwin; van Vliet-Ostaptchouk Jana V; van 't Riet Esther; van Haeften Timon W; Arp Pascal A; Hansen Torben; Kremer Dennis; Groenewoud Marlous J; van Hove Els C; Romijn Johannes A; Smit Jan W A; Nijpels Giel; Heine Robert J; Uitterlinden André G; Pedersen Oluf; Slagboom P Eline; Maassen Johannes A; Hofker Marten H; 't Hart Leen M; Dekker Jacqueline M
Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study.
European journal of human genetics : EJHG 2009;17(8):1056-62.
2009: Kolberg Janice A; Jørgensen Torben; Gerwien Robert W; Hamren Sarah; McKenna Michael P; Moler Edward; Rowe Michael W; Urdea Mickey S; Xu Xiaomei M; Hansen Torben; Pedersen Oluf; Borch-Johnsen Knut
Development of a type 2 diabetes risk model from a panel of serum biomarkers from the Inter99 cohort.
Diabetes care 2009;32(7):1207-12.
2009: Clausen Tine D; Mathiesen Elisabeth R; Hansen Torben; Pedersen Oluf; Jensen Dorte M; Lauenborg Jeannet; Schmidt Lone; Damm Peter
Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes.
The Journal of clinical endocrinology and metabolism 2009;94(7):2464-70.
2009: Sparsø T; Grarup N; Andreasen C; Albrechtsen A; Holmkvist J; Andersen G; Jørgensen T; Borch-Johnsen K; Sandbaek A; Lauritzen T; Madsbad S; Hansen T; Pedersen O
Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction.
Diabetologia 2009;52(7):1308-14.
2009: Pilgaard K; Jensen C B; Schou J H; Lyssenko V; Wegner L; Brøns C; Vilsbøll T; Hansen T; Madsbad S; Holst J J; Vølund A; Poulsen P; Groop L; Pedersen O; Vaag A A
The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.
Diabetologia 2009;52(7):1298-307.
2009: Sparsø Thomas; Bonnefond Amélie; Andersson Ehm; Bouatia-Naji Nabila; Holmkvist Johan; Wegner Lise; Grarup Niels; Gjesing Anette P; Banasik Karina; Cavalcanti-Proença Christine; Marchand Marion; Vaxillaire Martine; Charpentier Guillaume; Jarvelin Marjo-Riitta; Tichet Jean; Balkau Beverley; Marre Michel; Lévy-Marchal Claire; Faerch Kristine; Borch-Johnsen Knut; Jørgensen Torben; Madsbad Sten; Poulsen Pernille; Vaag Allan; Dina Christian; Hansen Torben; Pedersen Oluf; Froguel Philippe
G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.
Diabetes 2009;58(6):1450-6.
2009: Engberg Susanne; Vistisen Dorte; Lau Cathrine; Glümer Charlotte; Jørgensen Torben; Pedersen Oluf; Borch-Johnsen Knut
Progression to impaired glucose regulation and diabetes in the population-based Inter99 study.
Diabetes care 2009;32(4):606-11.
2009: Gylvin T; Ek J; Nolsøe R; Albrechtsen A; Andersen G; Bergholdt R; Brorsson C; Bang-Berthelsen C H; Hansen T; Karlsen A E; Billestrup N; Borch-Johnsen K; Jørgensen T; Pedersen O; Mandrup-Poulsen T; Nerup J; Pociot F
Functional SOCS1 polymorphisms are associated with variation in obesity in whites.
Diabetes, obesity & metabolism 2009;11(3):196-203.
2009: Lau Cathrine; Toft Ulla; Tetens Inge; Carstensen Bendix; Jørgensen Torben; Pedersen Oluf; Borch-Johnsen Knut
Dietary patterns predict changes in two-hour post-oral glucose tolerance test plasma glucose concentrations in middle-aged adults.
The Journal of nutrition 2009;139(3):588-93.
2009: Zobel Dorit P; Andreasen Camilla H; Grarup Niels; Eiberg Hans; Sørensen Thorkild I A; Sandbaek Annelli; Lauritzen Torsten; Borch-Johnsen Knut; Jørgensen Torben; Pedersen Oluf; Hansen Torben
Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes.
Diabetes 2009;58(3):757-64.
2009: Grunnet Louise G; Brøns Charlotte; Jacobsen Stine; Nilsson Emma; Astrup Arne; Hansen Torben; Pedersen Oluf; Poulsen Pernille; Quistorff Bjørn; Vaag Allan
Increased recovery rates of phosphocreatine and inorganic phosphate after isometric contraction in oxidative muscle fibers and elevated hepatic insulin resistance in homozygous carriers of the A-allele of FTO rs9939609.
The Journal of clinical endocrinology and metabolism 2009;94(2):596-602.
2009: Lauenborg Jeannet; Grarup Niels; Damm Peter; Borch-Johnsen Knut; Jørgensen Torben; Pedersen Oluf; Hansen Torben
Common type 2 diabetes risk gene variants associate with gestational diabetes.
The Journal of clinical endocrinology and metabolism 2009;94(1):145-50.
2009: Lund Søren S; Tarnow Lise; Frandsen Merete; Nielsen Bente B; Hansen Birgitte V; Pedersen Oluf; Parving Hans-Henrik; Vaag Allan A
Combining insulin with metformin or an insulin secretagogue in non-obese patients with type 2 diabetes: 12 month, randomised, double blind trial.
BMJ (Clinical research ed.) 2009;339():b4324.
2009: Boesgaard Trine Welløv; Gjesing Anette Prior; Grarup Niels; Rutanen Jarno; Jansson Per-Anders; Hribal Marta Letizia; Sesti Giorgio; Fritsche Andreas; Stefan Norbert; Staiger Harald; Häring Hans; Smith Ulf; Laakso Markku; Pedersen Oluf; Hansen Torben;
Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study.
PloS one 2009;4(9):e7236.
2009: Gjesing Anette P; Sparsø Thomas; Borch-Johnsen Knut; Jørgensen Torben; Pedersen Oluf; Hansen Torben; Olsen Niels V
No consistent effect of ADRB2 haplotypes on obesity, hypertension and quantitative traits of body fatness and blood pressure among 6,514 adult danes.
PloS one 2009;4(9):e7206.
2009: Kring Sofia I I; Werge Thomas; Holst Claus; Toubro Søren; Astrup Arne; Hansen Torben; Pedersen Oluf; Sørensen Thorkild I A
Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes.
PloS one 2009;4(8):e6696.
2009: Rathcke Camilla Noelle; Holmkvist Johan; Husmoen Lise Lotte N; Hansen Torben; Pedersen Oluf; Vestergaard Henrik; Linneberg Allan
Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults.
PloS one 2009;4(7):e6106.
2009: Holmkvist Johan; Banasik Karina; Andersen Gitte; Unoki Hiroyuki; Jensen Thomas Skot; Pisinger Charlotta; Borch-Johnsen Knut; Sandbaek Annelli; Lauritzen Torsten; Brunak Sören; Maeda Shiro; Hansen Torben; Pedersen Oluf
The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load.
PloS one 2009;4(6):e5872.
2009: Andreasen Camilla Helene; Mogensen Mette Sloth; Borch-Johnsen Knut; Sandbaek Annelli; Lauritzen Torsten; Almind Katrine; Hansen Lars; Jørgensen Torben; Pedersen Oluf; Hansen Torben
Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes.
BMC medical genetics 2009;10():17.
2009: Zimmermann Esther; Kring Sofia I I; Berentzen Tina L; Holst Claus; Pers Tune H; Hansen Torben; Pedersen Oluf; Sørensen Thorkild I A; Jess Tine
Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men.
PloS one 2009;4(2):e4428.
2008: Nielsen Trine; Burgdorf Kristoffer Sølvsten; Grarup Niels; Borch-Johnsen Knut; Hansen Torben; Jørgensen Torben; Pedersen Oluf; Andersen Gitte
The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes.
Journal of hypertension 2008;26(11):2142-6.
2008: Wegner Lise; Hussain Meena S; Pilgaard Kasper; Hansen Torben; Pedersen Oluf; Vaag Allan; Poulsen Pernille
Impact of TCF7L2 rs7903146 on insulin secretion and action in young and elderly Danish twins.
The Journal of clinical endocrinology and metabolism 2008;93(10):4013-9.
2008: Vimaleswaran Karani Santhanakrishnan; Luan Jian'an; Andersen Gitte; Muller Y Li; Wheeler Eleanor; Brito Ema C; O'Rahilly Stephen; Pedersen Oluf; Baier Leslie J; Knowler William C; Barroso Inês; Wareham Nicholas J; Loos Ruth J F; Franks Paul W
The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals.
Journal of applied physiology (Bethesda, Md. : 1985) 2008;105(4):1352-8.
2008: Unoki Hiroyuki; Takahashi Atsushi; Kawaguchi Takahisa; Hara Kazuo; Horikoshi Momoko; Andersen Gitte; Ng Daniel P K; Holmkvist Johan; Borch-Johnsen Knut; Jørgensen Torben; Sandbaek Annelli; Lauritzen Torsten; Hansen Torben; Nurbaya Siti; Tsunoda Tatsuhiko; Kubo Michiaki; Babazono Tetsuya; Hirose Hiroshi; Hayashi Matsuhiko; Iwamoto Yasuhiko; Kashiwagi Atsunori; Kaku Kohei; Kawamori Ryuzo; Tai E Shyong; Pedersen Oluf; Kamatani Naoyuki; Kadowaki Takashi; Kikkawa Ryuichi; Nakamura Yusuke; Maeda Shiro
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
Nature genetics 2008;40(9):1098-102.
2008: Jess T; Zimmermann E; Kring S I I; Berentzen T; Holst C; Toubro S; Astrup A; Hansen T; Pedersen O; Sørensen T I A
Impact on weight dynamics and general growth of the common FTO rs9939609: a longitudinal Danish cohort study.
International journal of obesity (2005) 2008;32(9):1388-94.
2008: Sparsø T; Andersen G; Albrechtsen A; Jørgensen T; Borch-Johnsen K; Sandbaek A; Lauritzen T; Wasson J; Permutt M A; Glaser B; Madsbad S; Pedersen O; Hansen T
Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation.
Diabetologia 2008;51(9):1646-52.
2008: Grarup Niels; Andersen Gitte; Krarup Nikolaj T; Albrechtsen Anders; Schmitz Ole; Jørgensen Torben; Borch-Johnsen Knut; Hansen Torben; Pedersen Oluf
Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.
Diabetes 2008;57(9):2534-40.
2008: Gutiérrez-Aguilar Ruth; Froguel Philippe; Hamid Yasmin H; Benmezroua Yamina; Jørgensen Torben; Borch-Johnsen Knut; Hansen Torben; Pedersen Oluf; Neve Bernadette
Genetic analysis of Kruppel-like zinc finger 11 variants in 5864 Danish individuals: potential effect on insulin resistance and modified signal transducer and activator of transcription-3 binding by promoter variant -1659G>C.
The Journal of clinical endocrinology and metabolism 2008;93(8):3128-35.
2008: Gaede Peter; Valentine William J; Palmer Andrew J; Tucker Daniel M D; Lammert Morten; Parving Hans-Henrik; Pedersen Oluf
Cost-effectiveness of intensified versus conventional multifactorial intervention in type 2 diabetes: results and projections from the Steno-2 study.
Diabetes care 2008;31(8):1510-5.
2008: Gonsorcíková Lucie; Pruhová Stepánka; Cinek Ondrej; Ek Jakob; Pelikánová Terezie; Jørgensen Torben; Eiberg Hans; Pedersen Oluf; Hansen Torben; Lebl Jan
Autosomal inheritance of diabetes in two families characterized by obesity and a novel H241Q mutation in NEUROD1.
Pediatric diabetes 2008;9(4 Pt 2):367-72.
2008: Jorsal A; Tarnow L; Lajer M; Ek J; Hansen T; Pedersen O; Parving H-H
The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy.
Molecular genetics and metabolism 2008;94(3):347-51.
2008: Benzinou Michael; Chèvre Jean-Claude; Ward Kirsten J; Lecoeur Cécile; Dina Christian; Lobbens Stephane; Durand Emmanuelle; Delplanque Jérome; Horber Fritz F; Heude Barbara; Balkau Beverley; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf; Meyre David; Froguel Philippe
Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations.
Human molecular genetics 2008;17(13):1916-21.
2008: Colombo Carlo; Porzio Ottavia; Liu Ming; Massa Ornella; Vasta Mario; Salardi Silvana; Beccaria Luciano; Monciotti Carla; Toni Sonia; Pedersen Oluf; Hansen Torben; Federici Luca; Pesavento Roberta; Cadario Francesco; Federici Giorgio; Ghirri Paolo; Arvan Peter; Iafusco Dario; Barbetti Fabrizio;
Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus.
The Journal of clinical investigation 2008;118(6):2148-56.
2008: Grarup Niels; Andreasen Camilla H; Andersen Mette K; Albrechtsen Anders; Sandbaek Annelli; Lauritzen Torsten; Borch-Johnsen Knut; Jørgensen Torben; Schmitz Ole; Hansen Torben; Pedersen Oluf
The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects.
The Journal of clinical endocrinology and metabolism 2008;93(6):2294-9.
2008: Lund Søren S; Tarnow Lise; Stehouwer Coen D A; Schalkwijk Casper G; Teerlink Tom; Gram Jørgen; Winther Kaj; Frandsen Merete; Smidt Ulla M; Pedersen Oluf; Parving Hans-Henrik; Vaag Allan A
Impact of metformin versus repaglinide on non-glycaemic cardiovascular risk markers related to inflammation and endothelial dysfunction in non-obese patients with type 2 diabetes.
European journal of endocrinology / European Federation of Endocrine Societies 2008;158(5):631-41.
2008: Boesgaard T W; Zilinskaite J; Vänttinen M; Laakso M; Jansson P-A; Hammarstedt A; Smith U; Stefan N; Fritsche A; Häring H; Hribal M; Sesti G; Zobel D P; Pedersen O; Hansen T;
The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study.
Diabetologia 2008;51(5):816-20.
2008: Faerch K; Vaag A; Holst J J; Glümer C; Pedersen O; Borch-Johnsen K
Impaired fasting glycaemia vs impaired glucose tolerance: similar impairment of pancreatic alpha and beta cell function but differential roles of incretin hormones and insulin action.
Diabetologia 2008;51(5):853-61.
2008: Andersen Gitte; Burgdorf Kristoffer Sølvsten; Sparsø Thomas; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects.
Diabetes 2008;57(5):1427-32.
2008: Stancáková Alena; Pihlajamäki Jussi; Kuusisto Johanna; Stefan Norbert; Fritsche Andreas; Häring Hans; Andreozzi Francesco; Succurro Elena; Sesti Giorgio; Boesgaard Trine Welløv; Hansen Torben; Pedersen Oluf; Jansson Per Anders; Hammarstedt Ann; Smith Ulf; Laakso Markku;
Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance.
The Journal of clinical endocrinology and metabolism 2008;93(5):1924-30.
2008: Gjesing A P; Andersen G; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Association of the beta3-adrenergic receptor Trp64Arg polymorphism with common metabolic traits: studies of 7605 middle-aged white people.
Molecular genetics and metabolism 2008;94(1):90-7.
2008: Holmkvist J; Anthonsen S; Wegner L; Andersen G; Jørgensen T; Borch-Johnsen K; Sandbaek A; Lauritzen T; Pedersen O; Hansen T
Polymorphisms in AHI1 are not associated with type 2 diabetes or related phenotypes in Danes: non-replication of a genome-wide association result.
Diabetologia 2008;51(4):609-14.
2008: Grarup Niels; Stender-Petersen Kirstine L; Andersson Ehm A; Jørgensen Torben; Borch-Johnsen Knut; Sandbaek Annelli; Lauritzen Torsten; Schmitz Ole; Hansen Torben; Pedersen Oluf
Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: a study of 15,734 Danish subjects.
Diabetes 2008;57(4):1136-42.
2008: Laakso M; Zilinskaite J; Hansen T; Boesgaard T Welløv; Vänttinen M; Stancáková A; Jansson P-A; Pellmé F; Holst J J; Kuulasmaa T; Hribal M L; Sesti G; Stefan N; Fritsche A; Häring H; Pedersen O; Smith U;
Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study.
Diabetologia 2008;51(3):502-11.
2008: Gaede Peter; Lund-Andersen Henrik; Parving Hans-Henrik; Pedersen Oluf
Effect of a multifactorial intervention on mortality in type 2 diabetes.
The New England journal of medicine 2008;358(6):580-91.
2008: Staiger Harald; Stancáková Alena; Zilinskaite Jone; Vänttinen Markku; Hansen Torben; Marini Maria Adelaide; Hammarstedt Ann; Jansson Per-Anders; Sesti Giorgio; Smith Ulf; Pedersen Oluf; Laakso Markku; Stefan Norbert; Fritsche Andreas; Häring Hans-Ulrich
A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study.
Diabetes 2008;57(2):514-7.
2008: Clausen Tine D; Mathiesen Elisabeth R; Hansen Torben; Pedersen Oluf; Jensen Dorte M; Lauenborg Jeannet; Damm Peter
High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia.
Diabetes care 2008;31(2):340-6.
2008: Lund Søren S; Tarnow Lise; Frandsen Merete; Smidt Ulla M; Pedersen Oluf; Parving Hans-Henrik; Vaag Allan A
Impact of metformin versus the prandial insulin secretagogue, repaglinide, on fasting and postprandial glucose and lipid responses in non-obese patients with type 2 diabetes.
European journal of endocrinology / European Federation of Endocrine Societies 2008;158(1):35-46.
2008: Sparsø T; Andersen G; Nielsen T; Burgdorf K S; Gjesing A P; Nielsen A L; Albrechtsen A; Rasmussen S S; Jørgensen T; Borch-Johnsen K; Sandbaek A; Lauritzen T; Madsbad S; Hansen T; Pedersen O
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.
Diabetologia 2008;51(1):70-5.
2008: Andreasen Camilla H; Stender-Petersen Kirstine L; Mogensen Mette S; Torekov Signe S; Wegner Lise; Andersen Gitte; Nielsen Arne L; Albrechtsen Anders; Borch-Johnsen Knut; Rasmussen Signe S; Clausen Jesper O; Sandbaek Annelli; Lauritzen Torsten; Hansen Lars; Jørgensen Torben; Pedersen Oluf; Hansen Torben
Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation.
Diabetes 2008;57(1):95-101.
2008: Andreasen Camilla Helene; Mogensen Mette Sloth; Borch-Johnsen Knut; Sandbaek Annelli; Lauritzen Torsten; Almind Katrine; Hansen Lars; Jørgensen Torben; Pedersen Oluf; Hansen Torben
Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits.
BMC medical genetics 2008;9():118.
2008: Friedrich Björn; Weyrich Peter; Stancáková Alena; Wang Jianjung; Kuusisto Johanna; Laakso Markku; Sesti Giorgio; Succurro Elena; Smith Ulf; Hansen Torben; Pedersen Oluf; Machicao Fausto; Schäfer Silke; Lang Florian; Risler Teut; Ullrich Susanne; Stefan Norbert; Fritsche Andreas; Häring Hans-Ulrich
Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.
PloS one 2008;3(11):e3506.
2008: Kring Sofia I I; Holst Claus; Zimmermann Esther; Jess Tine; Berentzen Tina; Toubro Søren; Hansen Torben; Astrup Arne; Pedersen Oluf; Sørensen Thorkild I A
FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness.
PloS one 2008;3(8):e2958.
2008: Andreasen Camilla H; Mogensen Mette S; Borch-Johnsen Knut; Sandbaek Annelli; Lauritzen Torsten; Sørensen Thorkild I A; Hansen Lars; Almind Katrine; Jørgensen Torben; Pedersen Oluf; Hansen Torben
Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes.
PloS one 2008;3(8):e2872.
2007: Grarup Niels; Rose Chrisian S; Andersson Ehm A; Andersen Gitte; Nielsen Arne L; Albrechtsen Anders; Clausen Jesper O; Rasmussen Signe S; Jørgensen Torben; Sandbaek Annelli; Lauritzen Torsten; Schmitz Ole; Hansen Torben; Pedersen Oluf
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.
Diabetes 2007;56(12):3105-11.
2007: Porzio O; Massa O; Cunsolo V; Colombo C; Malaponti M; Bertuzzi F; Hansen T; Johansen A; Pedersen O; Meschi F; Terrinoni A; Melino G; Federici M; Decarlo N; Menicagli M; Campani D; Marchetti P; Ferdaoussi M; Froguel P; Federici G; Vaxillaire M; Barbetti F
Missense mutations in the TGM2 gene encoding transglutaminase 2 are found in patients with early-onset type 2 diabetes. Mutation in brief no. 982. Online.
Human mutation 2007;28(11):1150.
2007: Sparsø Thomas; Hussain Meena Shaheen; Borch-Johnsen Knut; Jørgensen Torben; Madsbad Sten; Hansen Torben; Pedersen Oluf; Andersen Gitte
Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites.
Molecular genetics and metabolism 2007;92(3):278-82.
2007: Kamiyama Masumi; Kobayashi Masaaki; Araki Shin-ichi; Iida Aritoshi; Tsunoda Tatsuhiko; Kawai Koichi; Imanishi Masahito; Nomura Makoto; Babazono Tetsuya; Iwamoto Yasuhiko; Kashiwagi Atsunori; Kaku Kohei; Kawamori Ryuzou; Ng Daniel P K; Hansen Torben; Gaede Peter; Pedersen Oluf; Nakamura Yusuke; Maeda Shiro
Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
Human genetics 2007;122(3-4):397-407.
2007: Hainerová Irena; Larsen Lesli H; Holst Birgitte; Finková Marie; Hainer Vojtech; Lebl Jan; Hansen Torben; Pedersen Oluf
Melanocortin 4 receptor mutations in obese Czech children: studies of prevalence, phenotype development, weight reduction response, and functional analysis.
The Journal of clinical endocrinology and metabolism 2007;92(9):3689-96.
2007: Ling C; Wegner L; Andersen G; Almgren P; Hansen T; Pedersen O; Groop L; Vaag A; Poulsen P
Impact of the peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) Ala203Pro polymorphism on in vivo metabolism, PGC-1beta expression and fibre type composition in human skeletal muscle.
Diabetologia 2007;50(8):1615-20.
2007: Boesgaard T W; Castella S I; Andersen G; Albrechtsen A; Sparsø T; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(7):702-6.
2007: Dahlman Ingrid; Dicker Andrea; Jiao Hong; Kere Juha; Blomqvist Lennart; van Harmelen Vanessa; Hoffstedt Johan; Borch-Johnsen Knut; Jorgensen Torben; Hansen Torben; Pedersen Oluf; Laakso Markku; Arner Peter
A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis.
American journal of human genetics 2007;80(6):1115-24.
2007: Albrechtsen Anders; Castella Sofie; Andersen Gitte; Hansen Torben; Pedersen Oluf; Nielsen Rasmus
A Bayesian multilocus association method: allowing for higher-order interaction in association studies.
Genetics 2007;176(2):1197-208.
2007: Grarup N; Albrechtsen A; Ek J; Borch-Johnsen K; Jørgensen T; Schmitz O; Hansen T; Pedersen O
Variation in the peroxisome proliferator-activated receptor delta gene in relation to common metabolic traits in 7,495 middle-aged white people.
Diabetologia 2007;50(6):1201-8.
2007: Gaede Peter; Pedersen Oluf
Rosiglitazone monotherapy for type 2 diabetes mellitus-too soon to ADOPT?
Nature clinical practice. Endocrinology & metabolism 2007;3(6):456-7.
2007: Lund S S; Tarnow L; Stehouwer C D A; Schalkwijk C G; Frandsen M; Smidt U M; Pedersen O; Parving H-H; Vaag A
Targeting hyperglycaemia with either metformin or repaglinide in non-obese patients with type 2 diabetes: results from a randomized crossover trial.
Diabetes, obesity & metabolism 2007;9(3):394-407.
2007: Jensen Dorit P; Andreasen Camilla H; Andersen Mette K; Hansen Lars; Eiberg Hans; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites.
Journal of molecular medicine (Berlin, Germany) 2007;85(5):445-9.
2007: Gjesing A P; Andersen G; Albrechtsen A; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Studies of associations between the Arg389Gly polymorphism of the beta1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(4):392-7.
2007: Wegner Lise; Andersen Gitte; Sparsø Thomas; Grarup Niels; Glümer Charlotte; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites.
Diabetes 2007;56(3):694-8.
2007: Gjesing A P; Andersen G; Burgdorf K S; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects.
Diabetologia 2007;50(3):563-8.
2007: Hansen Torben; Drivsholm Thomas; Urhammer Søren A; Palacios Rene T; Vølund Aage; Borch-Johnsen Knut; Pedersen Oluf
The BIGTT test: a novel test for simultaneous measurement of pancreatic beta-cell function, insulin sensitivity, and glucose tolerance.
Diabetes care 2007;30(2):257-62.
2007: Sparsø Thomas; Hussain Meena S; Andersen Gitte; Hainerova Irena; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people.
Molecular genetics and metabolism 2007;90(2):205-9.
2007: Larsen L H; Rose C S; Sparsø T; Overgaard J; Torekov S S; Grarup N; Jensen D P; Albrechtsen A; Andersen G; Ek J; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes.
International journal of obesity (2005) 2007;31(2):365-70.
2007: Berentzen T; Petersen L; Pedersen O; Black E; Astrup A; Sørensen T I A
Long-term effects of leisure time physical activity on risk of insulin resistance and impaired glucose tolerance, allowing for body weight history, in Danish men.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(1):63-72.
2007: Pinterova D; Ek J; Kolostova K; Pruhova S; Novota P; Romzova M; Feigerlova E; Cerna M; Lebl J; Pedersen O; Hansen T
Six novel mutations in the GCK gene in MODY patients.
Clinical genetics 2007;71(1):95-6.
2007: Grarup Niels; Andersen Mette K; Andreasen Camilla H; Albrechtsen Anders; Borch-Johnsen Knut; Jørgensen Torben; Auwerx Johan; Schmitz Ole; Hansen Torben; Pedersen Oluf
Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects.
The Journal of clinical endocrinology and metabolism 2007;92(1):363-6.
2006: Santos Jose L; Boutin Philippe; Verdich Camilla; Holst Claus; Larsen Lesli H; Toubro Soren; Dina Christian; Saris Wim H M; Blaak Ellen E; Hoffstedt Johnatan; Taylor Moira A; Polak Jan; Clement Karine; Langin Dominique; Astrup Arne; Froguel Philippe; Pedersen Oluf; Sorensen Thorkild I A; Martinez J Alfredo;
Genotype-by-nutrient interactions assessed in European obese women. A case-only study.
European journal of nutrition 2006;45(8):454-62.
2006: Hainerová Irena; Torekov Signe S; Ek Jakob; Finková Marie; Borch-Johnsen Knut; Jørgensen Torben; Madsen Ole D; Lebl Jan; Hansen Torben; Pedersen Oluf
Association between neuromedin U gene variants and overweight and obesity.
The Journal of clinical endocrinology and metabolism 2006;91(12):5057-63.
2006: Jensen Dorit P; Urhammer Søren A; Eiberg Hans; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: studies in 6018 whites.
Molecular genetics and metabolism 2006;89(4):360-7.
2006: van Hove Els C; Hansen Torben; Dekker Jacqueline M; Reiling Erwin; Nijpels Giel; Jørgensen Torben; Borch-Johnsen Knut; Hamid Yasmin H; Heine Robert J; Pedersen Oluf; Maassen J Antonie; 't Hart Leen M
The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: the DAMAGE study.
Diabetes 2006;55(11):3193-6.
2006: Torekov S S; Larsen L H; Andersen G; Albrechtsen A; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects.
Diabetologia 2006;49(11):2653-8.
2006: Wegner L; Andersen G; Albrechtsen A; Sparsø T; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Large-scale study of the -232C > G polymorphism of PCK1 in Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2006;23(10):1140-4.
2006: Koefoed Theil Pernille; Kessel Line; Hansen Torben; Lund-Andersen Henrik; Pedersen Oluf; Larsen Michael
Lens fluorescence in relation to glucose tolerance and genetic predisposition to type 2 diabetes mellitus in a population-based study.
Current eye research 2006;31(9):733-8.
2006: Grarup N; Urhammer S A; Ek J; Albrechtsen A; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects.
Diabetologia 2006;49(9):2097-104.
2006: Feigerlová E; Pruhová S; Dittertová L; Lebl J; Pinterová D; Kolostová K; Cerná M; Pedersen O; Hansen T
Aetiological heterogeneity of asymptomatic hyperglycaemia in children and adolescents.
European journal of pediatrics 2006;165(7):446-52.
2006: Sørensen Thorkild I A; Boutin Philippe; Taylor Moira A; Larsen Lesli H; Verdich Camilla; Petersen Liselotte; Holst Claus; Echwald Søren M; Dina Christian; Toubro Søren; Petersen Martin; Polak Jan; Clément Karine; Martínez J Alfredo; Langin Dominique; Oppert Jean-Michel; Stich Vladimir; Macdonald Ian; Arner Peter; Saris Wim H M; Pedersen Oluf; Astrup Arne; Froguel Philippe;
Genetic polymorphisms and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets.
PLoS clinical trials 2006;1(2):e12.
2006: Ek Jakob; Hansen Sara P; Lajer Maria; Nicot Carine; Boesgaard Trine W; Pruhova Stepanka; Johansen Anders; Albrechtsen Anders; Yderstraede Knud; Lauenborg Jeannet; Parrizas Marcelina; Boj Sylvia F; Jørgensen Torben; Borch-Johnsen Knut; Damm Peter; Ferrer Jorge; Lebl Jan; Pedersen Oluf; Hansen Torben
A novel -192c/g mutation in the proximal P2 promoter of the hepatocyte nuclear factor-4 alpha gene (HNF4A) associates with late-onset diabetes.
Diabetes 2006;55(6):1869-73.
2006: Nolsøe R L; Hamid Y H; Pociot F; Paulsen S; Andersen K M; Borch-Johnsen K; Drivsholm T; Hansen T; Pedersen O; Mandrup-Poulsen T
Association of a microsatellite in FASL to type II diabetes and of the FAS-670G>A genotype to insulin resistance.
Genes and immunity 2006;7(4):316-21.
2006: Eiberg H; Hansen L; Kjer B; Hansen T; Pedersen O; Bille M; Rosenberg T; Tranebjaerg L
Autosomal dominant optic atrophy associated with hearing impairment and impaired glucose regulation caused by a missense mutation in the WFS1 gene.
Journal of medical genetics 2006;43(5):435-40.
2006: Rossing Peter; Rossing Kasper; Gaede Peter; Pedersen Oluf; Parving Hans-Henrik
Monitoring kidney function in type 2 diabetic patients with incipient and overt diabetic nephropathy.
Diabetes care 2006;29(5):1024-30.
2006: Buemann B; Astrup A; Pedersen O; Black E; Holst C; Toubro S; Echwald S; Holst J J; Rasmussen C; Sørensen T I A
Possible role of adiponectin and insulin sensitivity in mediating the favorable effects of lower body fat mass on blood lipids.
The Journal of clinical endocrinology and metabolism 2006;91(5):1698-704.
2006: Cheyssac Claire; Dina Christian; Leprêtre Frédéric; Vasseur-Delannoy Valérie; Dechaume Aurélie; Lobbens Stéphane; Balkau Beverley; Ruiz Juan; Charpentier Guillaume; Pattou François; Joly Erik; Prentki Marc; Hansen Torben; Pedersen Oluf; Vaxillaire Martine; Froguel Philippe
EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families.
Diabetes 2006;55(4):1171-6.
2006: Petersen M; Taylor M A; Saris W H M; Verdich C; Toubro S; Macdonald I; Rössner S; Stich V; Guy-Grand B; Langin D; Martinez J A; Pedersen O; Holst C; Sørensen T I A; Astrup A
Randomized, multi-center trial of two hypo-energetic diets in obese subjects: high- versus low-fat content.
International journal of obesity (2005) 2006;30(3):552-60.
2006: Gaede Peter; Parving Hans-Henrik; Pedersen Oluf
PROactive study.
Lancet 2006;367(9504):23-4; author reply 26-7.
2006: Johansen A; Jensen D P; Bergholdt R; Mortensen H B; Pociot F; Nerup J; Hansen T; Pedersen O;
IRS1, KCNJ11, PPARgamma2 and HNF-1alpha: do amino acid polymorphisms in these candidate genes support a shared aetiology between type 1 and type 2 diabetes?
Diabetes, obesity & metabolism 2006;8(1):75-82.
2006: Andersen G; Overgaard J; Albrechtsen A; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes.
Diabetologia 2006;49(1):75-82.
2005: Rose Christian S; Ek Jakob; Urhammer Søren A; Glümer Charlotte; Borch-Johnsen Knut; Jørgensen Torben; Pedersen Oluf; Hansen Torben
A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites.
Diabetes 2005;54(10):3026-31.
2005: Anuradha Shekher; Radha Venkatesan; Deepa Raj; Hansen Torben; Carstensen Bendix; Pedersen Oluf; Mohan Viswanathan
A prevalent amino acid polymorphism at codon 98 (Ala98Val) of the hepatocyte nuclear factor-1alpha is associated with maturity-onset diabetes of the young and younger age at onset of type 2 diabetes in Asian Indians.
Diabetes care 2005;28(10):2430-5.
2005: Black E; Holst C; Astrup A; Toubro S; Echwald S; Pedersen O; Sørensen T I A
Long-term influences of body-weight changes, independent of the attained weight, on risk of impaired glucose tolerance and Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(9):1199-205.
2005: Johansen A; Ek J; Mortensen H B; Pedersen O; Hansen T
Half of clinically defined maturity-onset diabetes of the young patients in Denmark do not have mutations in HNF4A, GCK, and TCF1.
The Journal of clinical endocrinology and metabolism 2005;90(8):4607-14.
2005: Torekov Signe S; Larsen Lesli H; Glümer Charlotte; Borch-Johnsen Knut; Jørgensen Torben; Holst Jens J; Madsen Ole D; Hansen Torben; Pedersen Oluf
Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes.
Diabetes 2005;54(7):2261-5.
2005: Rose C S; Andersen G; Hamid Y H; Glümer C; Drivsholm T; Borch-Johnsen K; Jørgensen T; Pedersen O; Hansen T
Studies of relationships between the GLUT10 Ala206Thr polymorphism and impaired insulin secretion.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(7):946-9.
2005: Lauenborg Jeannet; Mathiesen Elisabeth; Hansen Torben; Glümer Charlotte; Jørgensen Torben; Borch-Johnsen Knut; Hornnes Peter; Pedersen Oluf; Damm Peter
The prevalence of the metabolic syndrome in a danish population of women with previous gestational diabetes mellitus is three-fold higher than in the general population.
The Journal of clinical endocrinology and metabolism 2005;90(7):4004-10.
2005: Larsen Thomas M; Larsen Lesli H; Torekov Signe K; Ek Jakob; Black Eva; Toubro Søren; Astrup Arne; Sørensen Thorkild I A; Hansen Torben; Pedersen Oluf
Novel variants in the putative peroxisome proliferator-activated receptor {gamma} promoter and relationships with obesity in men.
Obesity research 2005;13(6):953-8.
2005: Lau Cathrine; Faerch Kristine; Glümer Charlotte; Tetens Inge; Pedersen Oluf; Carstensen Bendix; Jørgensen Torben; Borch-Johnsen Knut;
Dietary glycemic index, glycemic load, fiber, simple sugars, and insulin resistance: the Inter99 study.
Diabetes care 2005;28(6):1397-403.
2005: 't Hart Leen M; Hansen Torben; Rietveld Ingrid; Dekker Jacqueline M; Nijpels Giel; Janssen George M C; Arp Pascal A; Uitterlinden André G; Jørgensen Torben; Borch-Johnsen Knut; Pols Huibert A P; Pedersen Oluf; van Duijn Cornelia M; Heine Robert J; Maassen J Antonie
Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene.
Diabetes 2005;54(6):1892-5.
2005: Buemann B; Sørensen T I A; Pedersen O; Black E; Holst C; Toubro S; Echwald S; Holst J J; Rasmussen C; Astrup A
Lower-body fat mass as an independent marker of insulin sensitivity--the role of adiponectin.
International journal of obesity (2005) 2005;29(6):624-31.
2005: Hansen Sara K; Nielsen Eva-Maria D; Ek Jakob; Andersen Gitte; Glümer Charlotte; Carstensen Bendix; Mouritzen Peter; Drivsholm Thomas; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
Analysis of separate and combined effects of common variation in KCNJ11 and PPARG on risk of type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2005;90(6):3629-37.
2005: Buemann Benjamin; Black Eva; Holst Claus; Toubro Søren; Echwald Søren; Pedersen Oluf; Astrup Arne; Sørensen Thorkild
The N363S polymorphism of the glucocorticoid receptor and metabolic syndrome factors in men.
Obesity research 2005;13(5):862-7.
2005: Andersen G; Hansen T; Pedersen O
Genetics of common forms of glycaemia with pathological impact on vascular biology: are we on the right track?
Current molecular medicine 2005;5(3):261-74.
2005: Andersen G; Wegner L; Yanagisawa K; Rose C S; Lin J; Glümer C; Drivsholm T; Borch-Johnsen K; Jørgensen T; Hansen T; Spiegelman B M; Pedersen O
Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity.
Journal of medical genetics 2005;42(5):402-7.
2005: Pearson E R; Pruhova S; Tack C J; Johansen A; Castleden H A J; Lumb P J; Wierzbicki A S; Clark P M; Lebl J; Pedersen O; Ellard S; Hansen T; Hattersley A T
Molecular genetics and phenotypic characteristics of MODY caused by hepatocyte nuclear factor 4alpha mutations in a large European collection.
Diabetologia 2005;48(5):878-85.
2005: Nielsen Eva-Maria D; Hansen Lars; Stissing Trine; Yanagisawa Keiko; Borch-Johnsen Knut; Poulsen Pernille; Vaag Allan; Hansen Torben; Pedersen Oluf
Studies of variations of the cyclin-dependent kinase inhibitor 1C and the cyclin-dependent kinase 4 genes in relation to type 2 diabetes mellitus and related quantitative traits.
Journal of molecular medicine (Berlin, Germany) 2005;83(5):353-61.
2005: Larsen Lesli H; Gjesing Anette P; Sørensen Thorkild I A; Hamid Yasmin H; Echwald Søren M; Toubro Søren; Black Eva; Astrup Arne; Hansen Torben; Pedersen Oluf
Mutation analysis of the preproghrelin gene: no association with obesity and type 2 diabetes.
Clinical biochemistry 2005;38(5):420-4.
2005: Ek Jakob; Rose Christian Schack; Jensen Dorit Packert; Glümer Charlotte; Borch-Johnsen Knut; Jørgensen Torben; Pedersen Oluf; Hansen Torben
The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes.
The Journal of clinical endocrinology and metabolism 2005;90(5):3054-9.
2005: Gaede P; Pedersen O
Multi-targeted and aggressive treatment of patients with type 2 diabetes at high risk: what are we waiting for?
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2005;37 Suppl 1():76-82.
2005: Sagen J V; Pearson E R; Johansen A; Spyer G; Søvik O; Pedersen O; Njølstad P R; Hattersley A T; Hansen T
Preserved insulin response to tolbutamide in hepatocyte nuclear factor-1alpha mutation carriers.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(4):406-9.
2005: Andersen Gitte; Wegner Lise; Jensen Dorit Packert; Glümer Charlotte; Tarnow Lise; Drivsholm Thomas; Poulsen Pernille; Hansen Sara Kristine; Nielsen Eva-Maria Damsgaard; Ek Jakob; Mouritzen Peter; Vaag Allan; Parving Hans-Henrik; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
PGC-1alpha Gly482Ser polymorphism associates with hypertension among Danish whites.
Hypertension 2005;45(4):565-70.
2005: Neve Bernadette; Fernandez-Zapico Martin E; Ashkenazi-Katalan Vered; Dina Christian; Hamid Yasmin H; Joly Erik; Vaillant Emmanuel; Benmezroua Yamina; Durand Emmanuelle; Bakaher Nicolas; Delannoy Valerie; Vaxillaire Martine; Cook Tiffany; Dallinga-Thie Geesje M; Jansen Hans; Charles Marie-Aline; Clément Karine; Galan Pilar; Hercberg Serge; Helbecque Nicole; Charpentier Guillaume; Prentki Marc; Hansen Torben; Pedersen Oluf; Urrutia Raul; Melloul Danielle; Froguel Philippe
Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(13):4807-12.
2005: Hansen S K; Rose C S; Glümer C; Drivsholm T; Borch-Johnsen K; Jørgensen T; Pedersen O; Hansen T
Variation near the hepatocyte nuclear factor (HNF)-4alpha gene associates with type 2 diabetes in the Danish population.
Diabetologia 2005;48(3):452-8.
2005: Hamid Y H; Urhammer S A; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
The common T60N polymorphism of the lymphotoxin-alpha gene is associated with type 2 diabetes and other phenotypes of the metabolic syndrome.
Diabetologia 2005;48(3):445-51.
2005: Hansen Lars; Pedersen Oluf
Genetics of type 2 diabetes mellitus: status and perspectives.
Diabetes, obesity & metabolism 2005;7(2):122-35.
2005: Hamid Y H; Rose C S; Urhammer S A; Glümer C; Nolsøe R; Kristiansen O P; Mandrup-Poulsen T; Borch-Johnsen K; Jorgensen T; Hansen T; Pedersen O
Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes.
Diabetologia 2005;48(2):251-60.
2005: Gaede P; Hildebrandt P; Hess G; Parving H-H; Pedersen O
Plasma N-terminal pro-brain natriuretic peptide as a major risk marker for cardiovascular disease in patients with type 2 diabetes and microalbuminuria.
Diabetologia 2005;48(1):156-63.
2005: Hamid Y H; Vissing H; Holst B; Urhammer S A; Pyke C; Hansen S K; Glümer C; Borch-Johnsen K; Jørgensen T; Schwartz T W; Pedersen O; Hansen T
Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(1):74-80.
2005: Berentzen T; Dalgaard L T; Petersen L; Pedersen O; Sørensen T I A
Interactions between physical activity and variants of the genes encoding uncoupling proteins -2 and -3 in relation to body weight changes during a 10-y follow-up.
International journal of obesity (2005) 2005;29(1):93-9.
2005: Larsen Lesli H; Echwald Søren M; Sørensen Thorkild I A; Andersen Teis; Wulff Birgitte S; Pedersen Oluf
Prevalence of mutations and functional analyses of melanocortin 4 receptor variants identified among 750 men with juvenile-onset obesity.
The Journal of clinical endocrinology and metabolism 2005;90(1):219-24.
2005: Andersen Kirstine L; Echwald Søren M; Larsen Lesli H; Hamid Yasmin H; Glümer Charlotte; Jørgensen Torben; Borch-Johnsen Knut; Andersen Teis; Sørensen Thorkild I A; Hansen Torben; Pedersen Oluf
Variation of the McKusick-Kaufman gene and studies of relationships with common forms of obesity.
The Journal of clinical endocrinology and metabolism 2005;90(1):225-30.
2004: Lauenborg J; Damm P; Ek J; Glümer C; Jørgensen T; Borch-Johnsen K; Vestergaard H; Hornnes P; Pedersen O; Hansen T
Studies of the Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene and the relationship to beta-cell function during an OGTT in glucose-tolerant women with and without previous gestational diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association 2004;21(12):1310-5.
2004: Hamid Yasmin H; Urhammer Søren A; Jensen Dorit P; Glümer Charlotte; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites.
Diabetes 2004;53(12):3342-5.
2004: Gaede Peter; Pedersen Oluf
Intensive integrated therapy of type 2 diabetes: implications for long-term prognosis.
Diabetes 2004;53 Suppl 3():S39-47.
2004: Andersen Gitte; Wegner Lise; Rose Christian Schack; Xie Jianxin; Zhu Hao; Larade Kevin; Johansen Anders; Ek Jakob; Lauenborg Jeannet; Drivsholm Thomas; Borch-Johnsen Knut; Damm Peter; Hansen Torben; Bunn H Franklin; Pedersen Oluf
Variation in NCB5OR: studies of relationships to type 2 diabetes, maturity-onset diabetes of the young, and gestational diabetes mellitus.
Diabetes 2004;53(11):2992-7.
2004: Echwald Søren M; Andersen Kirstine L; Sørensen Thorkild I A; Larsen Lesli H; Andersen Teis; Tonooka Naoko; Tomura Hideaki; Takeda Jun; Pedersen Oluf
Mutation analysis of NR0B2 among 1545 Danish men identifies a novel c.278G>A (p.G93D) variant with reduced functional activity.
Human mutation 2004;24(5):381-7.
2004: Gaede Peter; Tarnow Lise; Vedel Pernille; Parving Hans-Henrik; Pedersen Oluf
Remission to normoalbuminuria during multifactorial treatment preserves kidney function in patients with type 2 diabetes and microalbuminuria.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(11):2784-8.
2004: Tornøe Christoffer W; Jacobsen Judith L; Pedersen Oluf; Hansen Torben; Madsen Henrik
Grey-box modelling of pharmacokinetic/pharmacodynamic systems.
Journal of pharmacokinetics and pharmacodynamics 2004;31(5):401-17.
2004: Hansen Lars; Gaster Michael; Oakeley Edward J; Brusgaard Klaus; Damsgaard Nielsen Eva-Maria; Beck-Nielsen Henning; Pedersen Oluf; Hemmings Brian A
Expression profiling of insulin action in human myotubes: induction of inflammatory and pro-angiogenic pathways in relationship with glycogen synthesis and type 2 diabetes.
Biochemical and biophysical research communications 2004;323(2):685-95.
2004: Nielsen Eva-Maria D; Hansen Lars; Lajer Maria; Andersen Kirstine L; Echwald Søren M; Urhammer Søren A; Hansen Torben; Pedersen Oluf
A common polymorphism in the promoter of the IGF-I gene associates with increased fasting serum triglyceride levels in glucose-tolerant subjects.
Clinical biochemistry 2004;37(8):660-5.
2004: Johansen A; Nielsen E-M D; Andersen G; Hamid Y H; Jensen D P; Glümer C; Drivsholm T; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion.
Diabetologia 2004;47(8):1437-41.
2004: Gylvin T; Nolsøe R; Hansen T; Nielsen E M D; Bergholdt R; Karlsen A E; Billestrup N; Borch-Johnsen K; Pedersen O; Mandrup-Poulsen T; Nerup J; Pociot F
Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity.
Diabetologia 2004;47(7):1273-7.
2004: Hansen S K; Gjesing A P; Rasmussen S K; Glümer C; Urhammer S A; Andersen G; Rose C S; Drivsholm T; Torekov S K; Jensen D P; Ekstrøm C T; Borch-Johnsen K; Jørgensen T; McCarthy M I; Hansen T; Pedersen O
Large-scale studies of the HphI insulin gene variable-number-of-tandem-repeats polymorphism in relation to Type 2 diabetes mellitus and insulin release.
Diabetologia 2004;47(6):1079-87.
2004: Højlund Kurt; Hansen Torben; Lajer Maria; Henriksen Jan Erik; Levin Klaus; Lindholm Jörgen; Pedersen Oluf; Beck-Nielsen Henning
A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene.
Diabetes 2004;53(6):1592-8.
2004: Lauenborg Jeannet; Hansen Torben; Jensen Dorte Møller; Vestergaard Henrik; Mølsted-Pedersen Lars; Hornnes Peter; Locht Henning; Pedersen Oluf; Damm Peter
Increasing incidence of diabetes after gestational diabetes: a long-term follow-up in a Danish population.
Diabetes care 2004;27(5):1194-9.
2004: Saudek Frantisek; Pruhová Stepánka; Boucek Peter; Lebl Jan; Adamec Milos; Ek Jakob; Pedersen Oluf; Hansen Torben
Maturity-onset diabetes of the young with end-stage nephropathy: a new indication for simultaneous pancreas and kidney transplantation?
Transplantation 2004;77(8):1298-301.
2004: Gaede Peter; Pedersen Oluf
Target intervention against multiple-risk markers to reduce cardiovascular disease in patients with type 2 diabetes.
Annals of medicine 2004;36(5):355-66.
2003: Morberg Cathrine M; Tetens Inge; Black Eva; Toubro Soeren; Soerensen Thorkild I A; Pedersen Oluf; Astrup Arne
Leptin and bone mineral density: a cross-sectional study in obese and nonobese men.
The Journal of clinical endocrinology and metabolism 2003;88(12):5795-800.
2003: Seibaek Marie; Vestergaard Henrik; Burchardt Hans; Sloth Carsten; Torp-Pedersen Christian; Nielsen Steen Levin; Hildebrandt Per; Pedersen Oluf
Insulin resistance and maximal oxygen uptake.
Clinical cardiology 2003;26(11):515-20.
2003: Dalgaard Louise T; Andersen Gitte; Larsen Lesli H; Sørensen Thorkild I A; Andersen Teis; Drivsholm Thomas; Borch-Johnsen Knut; Fleckner Jan; Hansen Torben; Din Nanni; Pedersen Oluf
Mutational analysis of the UCP2 core promoter and relationships of variants with obesity.
Obesity research 2003;11(11):1420-7.
2003: Yanagisawa K; Hingstrup Larsen L; Andersen G; Drivsholm T; Cederberg A; Westergren R; Borch-Johnsen K; Pedersen O; Enerbäck S; Hansen T
The FOXC2 -512C>T variant is associated with hypertriglyceridaemia and increased serum C-peptide in Danish Caucasian glucose-tolerant subjects.
Diabetologia 2003;46(11):1576-80.
2003: Andersen Gitte; Rose Christian Schack; Hamid Yasmin Hassan; Drivsholm Thomas; Borch-Johnsen Knut; Hansen Torben; Pedersen Oluf
Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary traits.
Diabetes 2003;52(9):2445-8.
2003: Pedersen Oluf; Gaede Peter
Intensified multifactorial intervention and cardiovascular outcome in type 2 diabetes: the Steno-2 study.
Metabolism: clinical and experimental 2003;52(8 Suppl 1):19-23.
2003: Nielsen Eva-Maria D; Hansen Lars; Echwald Søren M; Drivsholm Thomas; Borch-Johnsen Knut; Ekstrøm Claus T; Hansen Torben; Pedersen Oluf
Evidence for an association between the Leu162Val polymorphism of the PPARalpha gene and decreased fasting serum triglyceride levels in glucose tolerant subjects.
Pharmacogenetics 2003;13(7):417-23.
2003: Pildal J; Lajer M; Hansen S K; Almind K; Ambye L; Borch-Johnsen K; Carstensen B; Hansen T; Pedersen O
Studies of variability in the islet amyloid polypeptide gene in relation to Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2003;20(6):491-4.
2003: Muller Yunhua Li; Bogardus Clifton; Pedersen Oluf; Baier Leslie
A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians.
Diabetes 2003;52(3):895-8.
2003: Frayling Timothy M; Lindgren Cecilia M; Chevre Jean Claude; Menzel Stephan; Wishart Marie; Benmezroua Yamina; Brown Alison; Evans Julie C; Rao Pamidghantam Subba; Dina Christian; Lecoeur Cécile; Kanninen Timo; Almgren Peter; Bulman Michael P; Wang Youxiang; Mills James; Wright-Pascoe Rosemarie; Mahtani Melanie M; Prisco Francesco; Costa Angels; Cognet Ignacio; Hansen Torben; Pedersen Oluf; Ellard Sian; Tuomi Tiinamaija; Groop Leif C; Froguel Philippe; Hattersley Andrew T; Vaxillaire Martine
A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.
Diabetes 2003;52(3):872-81.
2003: Gaede Peter; Hansen Henrik Post; Parving Hans-Henrik; Pedersen Oluf
Impact of low-dose acetylsalicylic acid on kidney function in type 2 diabetic patients with elevated urinary albumin excretion rate.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(3):539-42.
2003: Pruhova S; Ek J; Lebl J; Sumnik Z; Saudek F; Andel M; Pedersen O; Hansen T
Genetic epidemiology of MODY in the Czech republic: new mutations in the MODY genes HNF-4alpha, GCK and HNF-1alpha.
Diabetologia 2003;46(2):291-5.
2003: Nielsen Eva-Maria D; Hansen Lars; Carstensen Bendix; Echwald Søren M; Drivsholm Thomas; Glümer Charlotte; Thorsteinsson Birger; Borch-Johnsen Knut; Hansen Torben; Pedersen Oluf
The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes.
Diabetes 2003;52(2):573-7.
2003: Gaede Peter; Vedel Pernille; Larsen Nicolai; Jensen Gunnar V H; Parving Hans-Henrik; Pedersen Oluf
Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes.
The New England journal of medicine 2003;348(5):383-93.
2003: Poulsen Pernille; Andersen Gitte; Fenger Mogens; Hansen Torben; Echwald Søren M; Vølund Aage; Beck-Nielsen Henning; Pedersen Oluf; Vaag Allan
Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both?
Diabetes 2003;52(1):194-8.
2002: Rasmussen Søren K; Urhammer Søren A; Berglund Lars; Jensen Jan N; Hansen Lars; Echwald Søren M; Borch-Johnsen Knut; Horikawa Yukio; Mashima Hirosato; Lithell Hans; Cox Nancy J; Hansen Torben; Bell Graeme I; Pedersen Oluf
Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians.
Diabetes 2002;51(12):3561-7.
2002: Hansen Sara K; Párrizas Marcelina; Jensen Maria L; Pruhova Stepanka; Ek Jakob; Boj Sylvia F; Johansen Anders; Maestro Miguel A; Rivera Francisca; Eiberg Hans; Andel Michal; Lebl Jan; Pedersen Oluf; Ferrer Jorge; Hansen Torben
Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function.
The Journal of clinical investigation 2002;110(6):827-33.
2002: Jacobsen Peter; Grarup Niels; Tarnow Lise; Parving Hans-Henrik; Pedersen Oluf
PC-1 amino acid variant (K121Q) has no impact on progression of diabetic nephropathy in type 1 diabetic patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(8):1408-12.
2002: Buhl Esben S; Jessen Niels; Pold Rasmus; Ledet Thomas; Flyvbjerg Allan; Pedersen Steen B; Pedersen Oluf; Schmitz Ole; Lund Sten
Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome.
Diabetes 2002;51(7):2199-206.
2002: Stride A; Vaxillaire M; Tuomi T; Barbetti F; Njølstad P R; Hansen T; Costa A; Conget I; Pedersen O; Søvik O; Lorini R; Groop L; Froguel P; Hattersley A T
The genetic abnormality in the beta cell determines the response to an oral glucose load.
Diabetologia 2002;45(3):427-35.
2002: Almind Katrine; Delahaye Laurent; Hansen Torben; Van Obberghen Emmanuel; Pedersen Oluf; Kahn C Ronald
Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2124-8.
2002: Black Eva; Petersen Liselotte; Kreutzer Martin; Toubro Søren; Sørensen Thorkild I A; Pedersen Oluf; Astrup Arne
Fat mass measured by DXA varies with scan velocity.
Obesity research 2002;10(2):69-77.
2002: Echwald Søren M; Bach Helle; Vestergaard Henrik; Richelsen Bjørn; Kristensen Kurt; Drivsholm Thomas; Borch-Johnsen Knut; Hansen Torben; Pedersen Oluf
A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro.
Diabetes 2002;51(1):1-6.
2001: Ek J; Andersen G; Urhammer S A; Gaede P H; Drivsholm T; Borch-Johnsen K; Hansen T; Pedersen O
Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus.
Diabetologia 2001;44(12):2220-6.
2001: Vestergaard H; Lund S; Pedersen O
Rosiglitazone treatment of patients with extreme insulin resistance and diabetes mellitus due to insulin receptor mutations has no effects on glucose and lipid metabolism.
Journal of internal medicine 2001;250(5):406-14.
2001: Hansen T; Ambye L; Grarup N; Hansen L; Echwald S M; Ferrer J; Pedersen O
Genetic variability of the SUR1 promoter in relation to beta-cell function and Type II diabetes mellitus.
Diabetologia 2001;44(10):1330-4.
2001: Echwald S M; Sørensen T I; Andersen T; Pedersen O
The Asn363Ser variant of the glucocorticoid receptor gene is not associated with obesity or weight gain in Danish men.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(10):1563-5.
2001: Ek J; Grarup N; Urhammer S A; Gaede P H; Drivsholm T; Borch-Johnsen K; Hansen T; Pedersen O
Studies of the variability of the hepatocyte nuclear factor-1beta (HNF-1beta / TCF2) and the dimerization cofactor of HNF-1 (DcoH / PCBD) genes in relation to type 2 diabetes mellitus and beta-cell function.
Human mutation 2001;18(4):356-7.
2001: Gaede P; Vedel P; Parving H H; Pedersen O
Elevated levels of plasma von Willebrand factor and the risk of macro- and microvascular disease in type 2 diabetic patients with microalbuminuria.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2001;16(10):2028-33.
2001: Gaede P; Poulsen H E; Parving H H; Pedersen O
Double-blind, randomised study of the effect of combined treatment with vitamin C and E on albuminuria in Type 2 diabetic patients.
Diabetic medicine : a journal of the British Diabetic Association 2001;18(9):756-60.
2001: Ek J; Andersen G; Urhammer S A; Hansen L; Carstensen B; Borch-Johnsen K; Drivsholm T; Berglund L; Hansen T; Lithell H; Pedersen O
Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) gene in relation to insulin sensitivity among glucose tolerant caucasians.
Diabetologia 2001;44(9):1170-6.
2001: Dalgaard L T; Hansen T; Urhammer S A; Drivsholm T; Borch-Johnsen K; Pedersen O
The uncoupling protein 3 -55 C -->T variant is not associated with Type II diabetes mellitus in Danish subjects.
Diabetologia 2001;44(8):1065-7.
2001: Dalgaard L T; Pedersen O
Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes.
Diabetologia 2001;44(8):946-65.
2001: Tarnow L; Grarup N; Hansen T; Parving H H; Pedersen O
Diabetic microvascular complications are not associated with two polymorphisms in the GLUT-1 and PC-1 genes regulating glucose metabolism in Caucasian type 1 diabetic patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2001;16(8):1653-6.
2001: Møller A M; Jensen N M; Pildal J; Drivsholm T; Borch-Johnsen K; Urhammer S A; Hansen T; Pedersen O
Studies of genetic variability of the glucose transporter 2 promoter in patients with type 2 diabetes mellitus.
The Journal of clinical endocrinology and metabolism 2001;86(5):2181-6.
2001: Buemann B; Schierning B; Toubro S; Bibby B M; Sørensen T; Dalgaard L; Pedersen O; Astrup A
The association between the val/ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiency.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(4):467-71.
2001: Dalgaard L T; Sørensen T I; Drivsholm T; Borch-Johnsen K; Andersen T; Hansen T; Pedersen O
A prevalent polymorphism in the promoter of the UCP3 gene and its relationship to body mass index and long term body weight change in the Danish population.
The Journal of clinical endocrinology and metabolism 2001;86(3):1398-402.
2001: Hansen L; Jensen J N; Ekstrøm C T; Vestergaard H; Hansen T; Pedersen O
Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus.
Diabetologia 2001;44(2):237-40.
2001: Gaede P; Beck M; Vedel P; Pedersen O
Limited impact of lifestyle education in patients with Type 2 diabetes mellitus and microalbuminuria: results from a randomized intervention study.
Diabetic medicine : a journal of the British Diabetic Association 2001;18(2):104-8.
2001: Jensen J N; Hansen L; Ekstrøm C T; Pociot F; Nerup J; Hansen T; Pedersen O
Polymorphisms in the neurogenin 3 gene (NEUROG) and their relation to altered insulin secretion and diabetes in the Danish Caucasian population.
Diabetologia 2001;44(1):123-6.
2001: Buhl E S; Jessen N; Schmitz O; Pedersen S B; Pedersen O; Holman G D; Lund S
Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner.
Diabetes 2001;50(1):12-7.
2000: Urhammer S A; Hansen T; Borch-Johnsen K; Pedersen O
Studies of the synergistic effect of the Trp/Arg64 polymorphism of the beta3-adrenergic receptor gene and the -3826 A-->G variant of the uncoupling protein-1 gene on features of obesity and insulin resistance in a population-based sample of 379 young Danish subjects.
The Journal of clinical endocrinology and metabolism 2000;85(9):3151-4.
2000: Rasmussen S K; Urhammer S A; Pizzuti A; Echwald S M; Ekstrøm C T; Hansen L; Hansen T; Borch-Johnsen K; Frittitta L; Trischitta V; Pedersen O
The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.
Diabetes 2000;49(9):1608-11.
2000: Rasmussen S K; Urhammer S A; Hansen T; Almind K; Møller A M; Borch-Johnsen K; Pedersen O
Variability of the insulin receptor substrate-1, hepatocyte nuclear factor-1alpha (HNF-1alpha), HNF-4alpha, and HNF-6 genes and size at birth in a population-based sample of young Danish subjects.
The Journal of clinical endocrinology and metabolism 2000;85(8):2951-3.
2000: Rasmussen S K; Hansen L; Frevert E U; Cohen P T; Kahn B B; Pedersen O
Adenovirus-mediated expression of a naturally occurring Asp905Tyr variant of the glycogen-associated regulatory subunit of protein phosphatase-1 in L6 myotubes.
Diabetologia 2000;43(6):718-22.
2000: Hansen L; Jensen J N; Urioste S; Petersen H V; Pociot F; Eiberg H; Kristiansen O P; Hansen T; Serup P; Nerup J; Pedersen O
NeuroD/BETA2 gene variability and diabetes: no associations to late-onset type 2 diabetes but an A45 allele may represent a susceptibility marker for type 1 diabetes among Danes. Danish Study Group of Diabetes in Childhood, and the Danish IDDM Epidemiology and Genetics Group.
Diabetes 2000;49(5):876-8.
2000: Rasmussen S K; Urhammer S A; Jensen J N; Hansen T; Borch-Johnsen K; Pedersen O
The -238 and -308 G-->A polymorphisms of the tumor necrosis factor alpha gene promoter are not associated with features of the insulin resistance syndrome or altered birth weight in Danish Caucasians.
The Journal of clinical endocrinology and metabolism 2000;85(4):1731-4.
2000: Rasmussen S K; Lautier C; Hansen L; Echwald S M; Hansen T; Ekstrøm C T; Urhammer S A; Borch-Johnsen K; Grigorescu F; Smith R J; Pedersen O
Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus.
The Journal of clinical endocrinology and metabolism 2000;85(4):1606-10.
2000: Hansen L; Urioste S; Petersen H V; Jensen J N; Eiberg H; Barbetti F; Serup P; Hansen T; Pedersen O
Missense mutations in the human insulin promoter factor-1 gene and their relation to maturity-onset diabetes of the young and late-onset type 2 diabetes mellitus in caucasians.
The Journal of clinical endocrinology and metabolism 2000;85(3):1323-6.
2000: Hansen L; Reneland R; Berglund L; Rasmussen S K; Hansen T; Lithell H; Pedersen O
Polymorphism in the glycogen-associated regulatory subunit of type 1 protein phosphatase (PPP1R3) gene and insulin sensitivity.
Diabetes 2000;49(2):298-301.
1999: Dalgaard L T; Sørensen T I; Andersen T; Hansen T; Pedersen O
An untranslated insertion variant in the uncoupling protein 2 gene is not related to body mass index and changes in body weight during a 26-year follow-up in Danish Caucasian men.
Diabetologia 1999;42(12):1413-6.
1999: Derave W; Lund S; Holman G D; Wojtaszewski J; Pedersen O; Richter E A
Contraction-stimulated muscle glucose transport and GLUT-4 surface content are dependent on glycogen content.
The American journal of physiology 1999;277(6 Pt 1):E1103-10.
1999: Echwald S M; Sørensen T I; Andersen T; Hansen C; Tommerup N; Pedersen O
Sequence variants in the human cocaine and amphetamine-regulated transcript (CART) gene in subjects with early onset obesity.
Obesity research 1999;7(6):532-6.
1999: Astrup A; Toubro S; Dalgaard L T; Urhammer S A; Sorensen T I; Pedersen O
Impact of the v/v 55 polymorphism of the uncoupling protein 2 gene on 24-h energy expenditure and substrate oxidation.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23(10):1030-4.
1999: Almind K; Frederiksen S K; Bernal D; Hansen T; Ambye L; Urhammer S; Ekstrøm C T; Berglund L; Reneland R; Lithell H; White M F; Van Obberghen E; Pedersen O
Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity.
Diabetologia 1999;42(10):1244-9.
1999: Møller A M; Ek J; Durviaux S M; Urhammer S A; Clausen J O; Eiberg H; Hansen T; Rousseau G G; Lemaigre F P; Pedersen O
Hepatocyte nuclear factor-6: associations between genetic variability and type II diabetes and between genetic variability and estimates of insulin secretion.
Diabetologia 1999;42(8):1011-6.
1999: Ek J; Urhammer S A; Sørensen T I; Andersen T; Auwerx J; Pedersen O
Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-gamma2 (PPAR-gamma2): divergent modulating effects on body mass index in obese and lean Caucasian men.
Diabetologia 1999;42(7):892-5.
1999: Almind K; Ahlgren M G; Hansen T; Urhammer S A; Clausen J O; Pedersen O
Discovery of a Met300Val variant in Shc and studies of its relationship to birth weight and length, impaired insulin secretion, insulin resistance, and type 2 diabetes mellitus.
The Journal of clinical endocrinology and metabolism 1999;84(6):2241-4.
1999: Tarnow L; Urhammer S A; Mottlau B; Hansen B V; Pedersen O; Parving H H
The Trp64Arg amino acid polymorphism of the beta3-adrenergic receptor gene does not contribute to the genetic susceptibility of diabetic microvascular complications in Caucasian type 1 diabetic patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1999;14(4):895-7.
1999: Orho-Melander M; Shimomura H; Sanke T; Rasmussen S K; Nanjo K; Pedersen O; Groop L C
Expression of naturally occurring variants in the muscle glycogen synthase gene.
Diabetes 1999;48(4):918-20.
1999: Dalgaard L T; Hansen T; Urhammer S A; Clausen J O; Eiberg H; Pedersen O
Intermediate expansions of a GAA repeat in the frataxin gene are not associated with type 2 diabetes or altered glucose-induced beta-cell function in Danish Caucasians.
Diabetes 1999;48(4):914-7.
1999: Echwald S M; Sørensen T I; Andersen T; Tybjaerg-Hansen A; Clausen J O; Pedersen O
Mutational analysis of the proopiomelanocortin gene in Caucasians with early onset obesity.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23(3):293-8.
1999: Hansen L; Fjordvang H; Rasmussen S K; Vestergaard H; Echwald S M; Hansen T; Alessi D; Shenolikar S; Saltiel A R; Barbetti F; Pedersen O
Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients.
Diabetes 1999;48(2):403-7.
1999: Gaede P; Vedel P; Parving H H; Pedersen O
Intensified multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: the Steno type 2 randomised study.
Lancet 1999;353(9153):617-22.
1999: Møller A M; Dalgaard L T; Ambye L; Hansen L; Schmitz O; Hansen T; Pedersen O
A novel Phe75fsdelT mutation in the hepatocyte nuclear factor-4alpha gene in a Danish pedigree with maturity-onset diabetes of the young.
The Journal of clinical endocrinology and metabolism 1999;84(1):367-9.
1998: Møller A M; Dalgaard L T; Pociot F; Nerup J; Hansen T; Pedersen O
Mutations in the hepatocyte nuclear factor-1alpha gene in Caucasian families originally classified as having Type I diabetes.
Diabetologia 1998;41(12):1528-31.
1998: Urhammer S A; Hansen T; Ekstrøm C T; Eiberg H; Pedersen O
The Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene contributes to the interindividual variation in serum C-peptide response during an oral glucose tolerance test: evidence from studies of 231 glucose-tolerant first degree relatives of type 2 diabetic probands.
The Journal of clinical endocrinology and metabolism 1998;83(12):4506-9.
1998: Urhammer S A; Møller A M; Nyholm B; Ekstrøm C T; Eiberg H; Clausen J O; Hansen T; Pedersen O; Schmitz O
The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1alpha gene on estimates of the pancreatic beta-cell function in Caucasian glucose-tolerant first-degree relatives of type 2 diabetic patients.
The Journal of clinical endocrinology and metabolism 1998;83(11):3992-5.
1998: Almind K; Ambye L; Urhammer S A; Hansen T; Echwald S M; Holst J J; Gromada J; Thorens B; Pedersen O
Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in Chinese hamster fibroblast cells.
Diabetologia 1998;41(10):1194-8.
1998: Echwald S M; Sørensen T I; Tybjaerg-Hansen A; Andersen T; Pedersen O
Gln27Glu variant of the human beta2-adrenoreceptor gene is not associated with early-onset obesity in Danish men.
Diabetes 1998;47(10):1657-8.
1998: Almind K; Frederiksen S K; Ahlgren M G; Urhammer S; Hansen T; Clausen J O; Pedersen O
Common amino acid substitutions in insulin receptor substrate-4 are not associated with Type II diabetes mellitus or insulin resistance.
Diabetologia 1998;41(8):969-74.
1998: Urhammer S A; Hansen T; Clausen J O; Eiberg H; Pedersen O
The g/a nucleotide variant at position -30 in the beta-cell-specific glucokinase gene promoter has no impact on the beta-cell function in Danish Caucasians.
Diabetes 1998;47(8):1359-61.
1998: Bernal D; Almind K; Yenush L; Ayoub M; Zhang Y; Rosshani L; Larsson C; Pedersen O; White M F
Insulin receptor substrate-2 amino acid polymorphisms are not associated with random type 2 diabetes among Caucasians.
Diabetes 1998;47(6):976-9.
1998: Hansen T; Echwald S M; Hansen L; Møller A M; Almind K; Clausen J O; Urhammer S A; Inoue H; Ferrer J; Bryan J; Aguilar-Bryan L; Permutt M A; Pedersen O
Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene.
Diabetes 1998;47(4):598-605.
1998: Urhammer S A; Dalgaard L T; Sørensen T I; Tybjaerg-Hansen A; Echwald S M; Andersen T; Clausen J O; Pedersen O
Organisation of the coding exons and mutational screening of the uncoupling protein 3 gene in subjects with juvenile-onset obesity.
Diabetologia 1998;41(2):241-4.
1997: Urhammer S A; Fridberg M; Sørensen T I; Echwald S M; Andersen T; Tybjaerg-Hansen A; Clausen J O; Pedersen O
Studies of genetic variability of the uncoupling protein 1 gene in Caucasian subjects with juvenile-onset obesity.
The Journal of clinical endocrinology and metabolism 1997;82(12):4069-74.
1997: Urhammer S A; Dalgaard L T; Sørensen T I; Møller A M; Andersen T; Tybjaerg-Hansen A; Hansen T; Clausen J O; Vestergaard H; Pedersen O
Mutational analysis of the coding region of the uncoupling protein 2 gene in obese NIDDM patients: impact of a common amino acid polymorphism on juvenile and maturity onset forms of obesity and insulin resistance.
Diabetologia 1997;40(10):1227-30.
1997: Møller A M; Urhammer S A; Dalgaard L T; Reneland R; Berglund L; Hansen T; Clausen J O; Lithell H; Pedersen O
Studies of the genetic variability of the coding region of the hepatocyte nuclear factor-4alpha in Caucasians with maturity onset NIDDM.
Diabetologia 1997;40(8):980-3.
1997: Hansen L; Arden K C; Rasmussen S B; Viars C S; Vestergaard H; Hansen T; Møller A M; Woodgett J R; Pedersen O
Chromosomal mapping and mutational analysis of the coding region of the glycogen synthase kinase-3alpha and beta isoforms in patients with NIDDM.
Diabetologia 1997;40(8):940-6.
1997: Seibaek M; Sloth C; Vallebo L; Hansen T; Urhammer S A; Burchardt H; Torp-Pedersen C; Pedersen O; Hildebrandt P
Glucose tolerance status and severity of coronary artery disease in men referred to coronary arteriography.
American heart journal 1997;133(6):622-9.
1997: Hansen L; Hansen T; Clausen J O; Echwald S M; Urhammer S A; Rasmussen S K; Pedersen O
The Val985Met insulin-receptor variant in the Danish Caucasian population: lack of associations with non-insulin-dependent diabetes mellitus or insulin resistance.
American journal of human genetics 1997;60(6):1532-5.
1997: Urhammer S A; Hansen T; Jensen L B; Clausen J O; Hansen L; Chui K C; Pedersen O
Studies of the impact of a liver glucokinase promoter variant on glucose tolerance and insulin sensitivity index.
The Journal of clinical endocrinology and metabolism 1997;82(6):1786-9.
1997: Vestergaard H; Rossen M; Urhammer S A; Müller J; Pedersen O
Short- and long-term metabolic effects of recombinant human IGF-I treatment in patients with severe insulin resistance and diabetes mellitus.
European journal of endocrinology / European Federation of Endocrine Societies 1997;136(5):475-82.
1997: Christiansen E; Schnider S; Palmvig B; Tauber-Lassen E; Pedersen O
Intake of a diet high in trans monounsaturated fatty acids or saturated fatty acids. Effects on postprandial insulinemia and glycemia in obese patients with NIDDM.
Diabetes care 1997;20(5):881-7.
1997: Nielsen F S; Gaede P; Vedel P; Pedersen O; Parving H H
White coat hypertension in NIDDM patients with and without incipient and overt diabetic nephropathy.
Diabetes care 1997;20(5):859-63.
1997: Urhammer S A; Fridberg M; Hansen T; Rasmussen S K; Møller A M; Clausen J O; Pedersen O
A prevalent amino acid polymorphism at codon 98 in the hepatocyte nuclear factor-1alpha gene is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge.
Diabetes 1997;46(5):912-6.
1997: Echwald S M; Sørensen T D; Sørensen T I; Tybjaerg-Hansen A; Andersen T; Chung W K; Leibel R L; Pedersen O
Amino acid variants in the human leptin receptor: lack of association to juvenile onset obesity.
Biochemical and biophysical research communications 1997;233(1):248-52.
1997: Echwald S M; Rasmussen S B; Sørensen T I; Andersen T; Tybjaerg-Hansen A; Clausen J O; Hansen L; Hansen T; Pedersen O
Identification of two novel missense mutations in the human OB gene.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1997;21(4):321-6.
1997: Urhammer S A; Rasmussen S K; Kaisaki P J; Oda N; Yamagata K; Møller A M; Fridberg M; Hansen L; Hansen T; Bell G I; Pedersen O
Genetic variation in the hepatocyte nuclear factor-1 alpha gene in Danish Caucasians with late-onset NIDDM.
Diabetologia 1997;40(4):473-5.
1997: Hansen T; Eiberg H; Rouard M; Vaxillaire M; Møller A M; Rasmussen S K; Fridberg M; Urhammer S A; Holst J J; Almind K; Echwald S M; Hansen L; Bell G I; Pedersen O
Novel MODY3 mutations in the hepatocyte nuclear factor-1alpha gene: evidence for a hyperexcitability of pancreatic beta-cells to intravenous secretagogues in a glucose-tolerant carrier of a P447L mutation.
Diabetes 1997;46(4):726-30.
1997: Hansen L; Echwald S M; Hansen T; Urhammer S A; Clausen J O; Pedersen O
Amino acid polymorphisms in the ATP-regulatable inward rectifier Kir6.2 and their relationships to glucose- and tolbutamide-induced insulin secretion, the insulin sensitivity index, and NIDDM.
Diabetes 1997;46(3):508-12.
1997: Hansen T; Andersen C B; Echwald S M; Urhammer S A; Clausen J O; Vestergaard H; Owens D; Hansen L; Pedersen O
Identification of a common amino acid polymorphism in the p85alpha regulatory subunit of phosphatidylinositol 3-kinase: effects on glucose disappearance constant, glucose effectiveness, and the insulin sensitivity index.
Diabetes 1997;46(3):494-501.
1996: Koefoed Theil P; Hansen T; Larsen M; Pedersen O; Lund-Andersen H
Lens autofluorescence is increased in newly diagnosed patients with NIDDM.
Diabetologia 1996;39(12):1524-7.
1996: Yamagata K; Oda N; Kaisaki P J; Menzel S; Furuta H; Vaxillaire M; Southam L; Cox R D; Lathrop G M; Boriraj V V; Chen X; Cox N J; Oda Y; Yano H; Le Beau M M; Yamada S; Nishigori H; Takeda J; Fajans S S; Hattersley A T; Iwasaki N; Hansen T; Pedersen O; Polonsky K S; Bell G I
Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
Nature 1996;384(6608):455-8.
1996: Christiansen E; Tibell A; Vølund A; Rasmussen K; Groth C G; Holst J J; Pedersen O; Christensen N J; Madsbad S
Pancreatic endocrine function in recipients of segmental and whole pancreas transplantation.
The Journal of clinical endocrinology and metabolism 1996;81(11):3972-9.
1996: Clausen J O; Borch-Johnsen K; Ibsen H; Bergman R N; Hougaard P; Winther K; Pedersen O
Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors.
The Journal of clinical investigation 1996;98(5):1195-209.
1996: Urhammer S A; Clausen J O; Hansen T; Pedersen O
Insulin sensitivity and body weight changes in young white carriers of the codon 64 amino acid polymorphism of the beta 3-adrenergic receptor gene.
Diabetes 1996;45(8):1115-20.
1996: Almind K; Inoue G; Pedersen O; Kahn C R
A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies.
The Journal of clinical investigation 1996;97(11):2569-75.
1995: Vestergaard H; Bjørbaek C; Hansen T; Larsen F S; Granner D K; Pedersen O
Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients.
The Journal of clinical investigation 1995;96(6):2639-45.
1995: Vestergaard H; Lund S; Bjørbaek C; Pedersen O
Unchanged gene expression of glycogen synthase in muscle from patients with NIDDM following sulphonylurea-induced improvement of glycaemic control.
Diabetologia 1995;38(10):1230-8.
1995: Hansen L; Hansen T; Vestergaard H; Bjørbaek C; Echwald S M; Clausen J O; Chen Y H; Chen M X; Cohen P T; Pedersen O
A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin.
Human molecular genetics 1995;4(8):1313-20.
1995: Vestergaard H; Skøtt P; Steffensen R; Wroblewski H; Pedersen O; Kastrup J
Insulin-resistant glucose metabolism in patients with microvascular angina--syndrome X.
Metabolism: clinical and experimental 1995;44(7):876-82.
1995: Vestergaard H; Klein H H; Hansen T; Müller J; Skovby F; Bjørbaek C; Røder M E; Pedersen O
Severe insulin-resistant diabetes mellitus in patients with congenital muscle fiber type disproportion myopathy.
The Journal of clinical investigation 1995;95(4):1925-32.
1995: Echwald S M; Bjørbaek C; Hansen T; Clausen J O; Vestergaard H; Zierath J R; Printz R L; Granner D K; Pedersen O
Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity.
Diabetes 1995;44(3):347-53.
1995: Vestergaard H; Parving H H; Hansen L; Pedersen O
Whole-body glucose metabolism in obese patients with type 2 diabetes mellitus: the impact of hypertension and strict blood glucose control.
Diabetic medicine : a journal of the British Diabetic Association 1995;12(2):156-63.
1995: Vestergaard H; Weinreb J E; Rosen A S; Bjørbaek C; Hansen L; Pedersen O; Kahn B B
Sulfonylurea therapy improves glucose disposal without changing skeletal muscle GLUT4 levels in noninsulin-dependent diabetes mellitus subjects: a longitudinal study.
The Journal of clinical endocrinology and metabolism 1995;80(1):270-5.
1994: Chen Y H; Hansen L; Chen M X; Bjørbaek C; Vestergaard H; Hansen T; Cohen P T; Pedersen O
Sequence of the human glycogen-associated regulatory subunit of type 1 protein phosphatase and analysis of its coding region and mRNA level in muscle from patients with NIDDM.
Diabetes 1994;43(10):1234-41.
1994: Pedersen O; Hansen L; Bak J F
Impaired glycogen synthesis of skeletal muscle in patients with insulin-resistant diabetes mellitus.
Journal of diabetes and its complications 1994;8(4):213-20.
1994: Bjørbaek C; Echwald S M; Hubricht P; Vestergaard H; Hansen T; Zierath J; Pedersen O
Genetic variants in promoters and coding regions of the muscle glycogen synthase and the insulin-responsive GLUT4 genes in NIDDM.
Diabetes 1994;43(8):976-83.
1994: Christiansen E; Tibell A; Groth C G; Rasmussen K; Pedersen O; Burcharth F; Christensen N J; Vølund A; Madsbad S
Limitations in the use of insulin or C-peptide alone in the assessment of beta-cell function in pancreas transplant recipients. Danish-Swedish Study Group of Metabolic Effect of Pancreas Transplantation.
Transplantation proceedings 1994;26(2):467-8.
1994: Vestergaard H; Andersen P H; Lund S; Vedel P; Pedersen O
Expression of glycogen synthase and phosphofructokinase in muscle from type 1 (insulin-dependent) diabetic patients before and after intensive insulin treatment.
Diabetologia 1994;37(1):82-90.
1993: Hansen T; Bjørbaek C; Vestergaard H; Grønskov K; Bak J F; Pedersen O
Expression of insulin receptor spliced variants and their functional correlates in muscle from patients with non-insulin-dependent diabetes mellitus.
The Journal of clinical endocrinology and metabolism 1993;77(6):1500-5.
1993: Almind K; Bjørbaek C; Vestergaard H; Hansen T; Echwald S; Pedersen O
Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.
Lancet 1993;342(8875):828-32.
1993: Stallknecht B; Andersen P H; Vinten J; Bendtsen L L; Sibbersen J; Pedersen O; Galbo H
Effect of physical training on glucose transporter protein and mRNA levels in rat adipocytes.
The American journal of physiology 1993;265(1 Pt 1):E128-34.
1993: Vestergaard H; Lund S; Larsen F S; Bjerrum O J; Pedersen O
Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin-resistant patients with non-insulin-dependent diabetes mellitus.
The Journal of clinical investigation 1993;91(6):2342-50.
1991: Vestergaard H; Bjørbaek C; Andersen P H; Bak J F; Pedersen O
Impaired expression of glycogen synthase mRNA in skeletal muscle of NIDDM patients.
Diabetes 1991;40(12):1740-5.
1990: Ploug T; Stallknecht B M; Pedersen O; Kahn B B; Ohkuwa T; Vinten J; Galbo H
Effect of endurance training on glucose transport capacity and glucose transporter expression in rat skeletal muscle.
The American journal of physiology 1990;259(6 Pt 1):E778-86.

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