FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Dehua Pei

Research Profile

Chemicals & Drugs

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Procedures

Co-author Network

Publications

TOP 3
Tao Liu; Ziqing Qian; Qing Xiao; Dehua Pei
High-throughput screening of one-bead-one-compound libraries: identification of cyclic peptidyl inhibitors against calcineurin/NFAT interaction.
Lige Ren; Xianwen Chen; Rinrada Luechapanichkul; Nicholas G Selner; Tiffany M Meyer; Anne-Sophie Wavreille; Richard Chan; Caterina Iorio; Xiang Zhou; Benjamin G Neel; Dehua Pei
Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2.
Ryan L Hard; J Liu; Juan Shen; Pei Zhou; Dehua Pei
HDAC6 and Ubp-M BUZ domains recognize specific C-terminal sequences of proteins.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Dehua Pei (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: Tao Liu; Ziqing Qian; Qing Xiao; Dehua Pei
High-throughput screening of one-bead-one-compound libraries: identification of cyclic peptidyl inhibitors against calcineurin/NFAT interaction.
ACS combinatorial science 2011;13(5):537-46.
2011: Lige Ren; Xianwen Chen; Rinrada Luechapanichkul; Nicholas G Selner; Tiffany M Meyer; Anne-Sophie Wavreille; Richard Chan; Caterina Iorio; Xiang Zhou; Benjamin G Neel; Dehua Pei
Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2.
Biochemistry 2011;50(12):2339-56.
2010: Ryan L Hard; J Liu; Juan Shen; Pei Zhou; Dehua Pei
HDAC6 and Ubp-M BUZ domains recognize specific C-terminal sequences of proteins.
Biochemistry 2010;49(50):10737-46.
2010: Xianwen Chen; Lige Ren; Soochong Kim; Nicholas Carpino; James L Daniel; Satya P Kunapuli; Alexander Y Tsygankov; Dehua Pei
Determination of the substrate specificity of protein-tyrosine phosphatase TULA-2 and identification of Syk as a TULA-2 substrate.
The Journal of biological chemistry 2010;285(41):31268-76.
2010: Qing Xiao; Feiran Zhang; Benjamin A Nacev; Jun O Liu; Dehua Pei
Protein N-terminal processing: substrate specificity of Escherichia coli and human methionine aminopeptidases.
Biochemistry 2010;49(26):5588-99.
2010: Dehua Pei
On-bead library screening made easier.
Chemistry & biology 2010;17(1):3-4.
2009: Yanyan Zhang; Anne-Sophie Wavreille; Andrew R Kunys; Dehua Pei
The SH2 domains of inositol polyphosphate 5-phosphatases SHIP1 and SHIP2 have similar ligand specificity but different binding kinetics.
Biochemistry 2009;48(46):11075-83.
2009: Xianwen Chen; Pauline H Tan; Yanyan Zhang; Dehua Pei
On-bead screening of combinatorial libraries: reduction of nonspecific binding by decreasing surface ligand density.
Journal of combinatorial chemistry 2009;11(4):604-11.
2009: Ozlem Dogan Ekici; Jinge Zhu; Ivy Yeuk Wah Chung; Mark Paetzel; Ross E Dalbey; Dehua Pei
Profiling the substrate specificity of viral protease VP4 by a FRET-based peptide library approach.
Biochemistry 2009;48(24):5753-9.
2009: Amit Thakkar; Allison S Cohen; Michael D Connolly; Ronald N Zuckermann; Dehua Pei
High-throughput sequencing of peptoids and peptide-peptoid hybrids by partial edman degradation and mass spectrometry.
Journal of combinatorial chemistry 2009;11(2):294-302.
2009: Tao Liu; Sang Hoon Joo; Jeffrey L Voorhees; Charles L Brooks; Dehua Pei
Synthesis and screening of a cyclic peptide library: discovery of small-molecule ligands against human prolactin receptor.
Bioorganic & medicinal chemistry 2009;17(3):1026-33.
2009: Bhaskar Gopishetty; Jinge Zhu; Rakhi Rajan; Adam J Sobczak; Stanislaw F Wnuk; Charles E Bell; Dehua Pei
Probing the catalytic mechanism of S-ribosylhomocysteinase (LuxS) with catalytic intermediates and substrate analogues.
Journal of the American Chemical Society 2009;131(3):1243-50.
2008: Gang Shen; Jinge Zhu; Anthony M Simpson; Dehua Pei
Design and synthesis of macrocyclic peptidyl hydroxamates as peptide deformylase inhibitors.
Bioorganic & medicinal chemistry letters 2008;18(10):3060-3.
2008: Sang Hoon Joo; Dehua Pei
Synthesis and screening of support-bound combinatorial peptide libraries with free C-termini: determination of the sequence specificity of PDZ domains.
Biochemistry 2008;47(9):3061-72.
2008: Yanyan Zhang; Shanggen Zhou; Anne-Sophie Wavreille; James DeWille; Dehua Pei
Cyclic peptidyl inhibitors of Grb2 and tensin SH2 domains identified from combinatorial libraries.
Journal of combinatorial chemistry 2008;10(2):247-55.
2008: Jinge Zhu; Dehua Pei
A LuxP-based fluorescent sensor for bacterial autoinducer II.
ACS chemical biology 2008;3(2):110-9.
2007: Kiet T Nguyen; Jen-Chieh Wu; Julie A Boylan; Frank C Gherardini; Dehua Pei
Zinc is the metal cofactor of Borrelia burgdorferi peptide deformylase.
Archives of biochemistry and biophysics 2007;468(2):217-25.
2007: Dehua Pei; Anne-Sophie Wavreille
Reverse interactomics: decoding protein-protein interactions with combinatorial peptide libraries.
Molecular bioSystems 2007;3(8):536-41.
2007: Anne-Sophie Wavreille; Mathieu Garaud; Yanyan Zhang; Dehua Pei
Defining SH2 domain and PTP specificity by screening combinatorial peptide libraries.
Methods (San Diego, Calif.) 2007;42(3):207-19.
2007: Qing Xiao; Dehua Pei
High-throughput synthesis and screening of cyclic peptide antibiotics.
Journal of medicinal chemistry 2007;50(13):3132-7.
2007: Mathieu Garaud; Dehua Pei
Substrate profiling of protein tyrosine phosphatase PTP1B by screening a combinatorial peptide library.
Journal of the American Chemical Society 2007;129(17):5366-7.
2007: Sathish Rajamani; Jinge Zhu; Dehua Pei; Richard T Sayre
A LuxP-FRET-based reporter for the detection and quantification of AI-2 bacterial quorum-sensing signal compounds.
Biochemistry 2007;46(13):3990-7.
2007: Anne-Sophie Wavreille; Dehua Pei
A chemical approach to the identification of tensin-binding proteins.
ACS chemical biology 2007;2(2):109-18.
2007: Ozlem Dogan Ekici; Andrew Karla; Mark Paetzel; Mark Lively; Dehua Pei; Ross E Dalbey
Altered -3 substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library.
The Journal of biological chemistry 2007;282(1):417-25.
2006: Michael C Sweeney; Xianxi Wang; Junguk Park; Yusen Liu; Dehua Pei
Determination of the sequence specificity of XIAP BIR domains by screening a combinatorial peptide library.
Biochemistry 2006;45(49):14740-8.
2006: Jinge Zhu; Sushilla Z Knottenbelt; Martin L Kirk; Dehua Pei
Catalytic mechanism of S-ribosylhomocysteinase: ionization state of active-site residues.
Biochemistry 2006;45(40):12195-203.
2006: Sang Hoon Joo; Qing Xiao; Yun Ling; Bhaskar Gopishetty; Dehua Pei
High-throughput sequence determination of cyclic peptide library members by partial Edman degradation/mass spectrometry.
Journal of the American Chemical Society 2006;128(39):13000-9.
2006: Amit Thakkar; Anne-Sophie Wavreille; Dehua Pei
Traceless capping agent for peptide sequencing by partial edman degradation and mass spectrometry.
Analytical chemistry 2006;78(16):5935-9.
2006: Diana Imhof; Anne-Sophie Wavreille; Andreas May; Martin Zacharias; Susheela Tridandapani; Dehua Pei
Sequence specificity of SHP-1 and SHP-2 Src homology 2 domains. Critical roles of residues beyond the pY+3 position.
The Journal of biological chemistry 2006;281(29):20271-82.
2006: Gang Shen; Rakhi Rajan; Jinge Zhu; Charles E Bell; Dehua Pei
Design and synthesis of substrate and intermediate analogue inhibitors of S-ribosylhomocysteinase.
Journal of medicinal chemistry 2006;49(10):3003-11.
2006: Xianxi Wang; Ranyia Matta; Gang Shen; Leif D Nelin; Dehua Pei; Yusen Liu
Mechanism of triptolide-induced apoptosis: Effect on caspase activation and Bid cleavage and essentiality of the hydroxyl group of triptolide.
Journal of molecular medicine (Berlin, Germany) 2006;84(5):405-15.
2005: Michael C Sweeney; Anne-Sophie Wavreille; Junguk Park; Jon Butchar; Susheela Tridandapani; Dehua Pei
Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains.
Biochemistry 2005;44(45):14932-47.
2005: Chuanguang Qin; Anne-Sophie Wavreille; Dehua Pei
Alternative mode of binding to phosphotyrosyl peptides by Src homology-2 domains.
Biochemistry 2005;44(36):12196-202.
2005: Kiet T Nguyen; Dehua Pei
Purification and characterization of enzymes involved in the degradation of chemotactic N-formyl peptides.
Biochemistry 2005;44(23):8514-22.
2005: Rakhi Rajan; Jinge Zhu; Xubo Hu; Dehua Pei; Charles E Bell
Crystal structure of S-ribosylhomocysteinase (LuxS) in complex with a catalytic 2-ketone intermediate.
Biochemistry 2005;44(10):3745-53.
2004: Junguk Park; Dehua Pei
trans-Beta-nitrostyrene derivatives as slow-binding inhibitors of protein tyrosine phosphatases.
Biochemistry 2004;43(47):15014-21.
2004: Jinge Zhu; Ilirian Dhimitruka; Dehua Pei
5-(2-Aminoethyl)dithio-2-nitrobenzoate as a more base-stable alternative to Ellman's reagent.
Organic letters 2004;6(21):3809-12.
2004: Dehua Pei; Jinge Zhu
Mechanism of action of S-ribosylhomocysteinase (LuxS).
Current opinion in chemical biology 2004;8(5):492-7.
2004: Xubo Hu; Kiet T Nguyen; Vernon Jiang; Denene Lofland; Heinz Moser; Dehua Pei
Macrocyclic inhibitors for peptide deformylase: a structure-activity relationship study of the ring size.
Journal of medicinal chemistry 2004;47(20):4941-9.
2004: Jinge Zhu; Reena Patel; Dehua Pei
Catalytic mechanism of S-ribosylhomocysteinase (LuxS): stereochemical course and kinetic isotope effect of proton transfer reactions.
Biochemistry 2004;43(31):10166-72.
2004: Kiet T Nguyen; Xubo Hu; Dehua Pei
Slow-binding inhibition of peptide deformylase by cyclic peptidomimetics as revealed by a new spectrophotometric assay.
Bioorganic chemistry 2004;32(3):178-91.
2004: Junguk Park; Hua Fu; Dehua Pei
Peptidyl aldehydes as slow-binding inhibitors of dual-specificity phosphatases.
Bioorganic & medicinal chemistry letters 2004;14(3):685-7.
2004: Xubo Hu; Jinge Zhu; Sumant Srivathsan; Dehua Pei
Peptidyl hydroxamic acids as methionine aminopeptidase inhibitors.
Bioorganic & medicinal chemistry letters 2004;14(1):77-9.
2004: Ming Xian; Zakia Fatima; Wei Zhang; Jianwen Fang; Hanfen Li; Dehua Pei; Joseph Loo; Tracy Stevenson; Peng George Wang
Identification of alpha-galactosyl epitope mimetics through rapid generation and screening of C-linked glycopeptide library.
Journal of combinatorial chemistry 2004;6(1):126-34.
2003: Jinge Zhu; Xubo Hu; Eric Dizin; Dehua Pei
Catalytic mechanism of S-ribosylhomocysteinase (LuxS): direct observation of ketone intermediates by 13C NMR spectroscopy.
Journal of the American Chemical Society 2003;125(44):13379-81.
2003: Xubo Hu; Kiet T Nguyen; Christophe Verlinde; Wim G J Hol; Dehua Pei
Structure-based design of a macrocyclic inhibitor for peptide deformylase.
Journal of medicinal chemistry 2003;46(18):3771-4.
2003: Kiet T Nguyen; Xubo Hu; Craig Colton; Ratna Chakrabarti; Michael X Zhu; Dehua Pei
Characterization of a human peptide deformylase: implications for antibacterial drug design.
Biochemistry 2003;42(33):9952-8.
2003: Junguk Park; Hua Fu; Dehua Pei
Peptidyl aldehydes as reversible covalent inhibitors of SRC homology 2 domains.
Biochemistry 2003;42(17):5159-67.
2003: Michael C Sweeney; Dehua Pei
An improved method for rapid sequencing of support-bound peptides by partial edman degradation and mass spectrometry.
Journal of combinatorial chemistry 2003;5(3):218-22.
2003: Jinge Zhu; Eric Dizin; Xubo Hu; Anne-Sophie Wavreille; Junguk Park; Dehua Pei
S-Ribosylhomocysteinase (LuxS) is a mononuclear iron protein.
Biochemistry 2003;42(16):4717-26.
2002: Gulnur Arabaci; Tian Yi; Hua Fu; Mary E Porter; Kirk D Beebe; Dehua Pei
alpha-bromoacetophenone derivatives as neutral protein tyrosine phosphatase inhibitors: structure-Activity relationship.
Bioorganic & medicinal chemistry letters 2002;12(21):3047-50.
2002: Hua Fu; Junguk Park; Dehua Pei
Peptidyl aldehydes as reversible covalent inhibitors of protein tyrosine phosphatases.
Biochemistry 2002;41(34):10700-9.
2002: Peng Wang; Hua Fu; Donald F Snavley; Michael A Freitas; Dehua Pei
Screening combinatorial libraries by mass spectrometry. 2. Identification of optimal substrates of protein tyrosine phosphatase SHP-1.
Biochemistry 2002;41(19):6202-10.
2001: Peng Wang; Gulnur Arabaci; Dehua Pei
Rapid sequencing of library-derived peptides by partial edman degradation and mass spectrometry.
Journal of combinatorial chemistry 2001;3(3):251-4.
2001: Peng Wang; D F Snavley; Michael A Freitas; Dehua Pei
Screening combinatorial libraries for optimal enzyme substrates by mass spectrometry.
Rapid communications in mass spectrometry : RCM 2001;15(14):1166-71.
2000: H Liao; Chunhua Yuan; Mei-I Su; Suganya Yongkiettrakul; Dongyan Qin; Hongyuan Li; In-Ja L Byeon; Dehua Pei; Ming-Daw Tsai
Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9.
Journal of molecular biology 2000;304(5):941-51.
2000: Y Wei; T Yi; KM Huntington; Chaity Chaudhury; Dehua Pei
Identification of a potent peptide deformylase inhibitor from a rationally designed combinatorial library.
Journal of combinatorial chemistry 2000;2(6):650-7.
2000: Kirk D Beebe; Peng Wang; Gulnur Arabaci; Dehua Pei
Determination of the binding specificity of the SH2 domains of protein tyrosine phosphatase SHP-1 through the screening of a combinatorial phosphotyrosyl peptide library.
Biochemistry 2000;39(43):13251-60.
2000: Peng Wang; In-Ja L Byeon; H Liao; Kirk D Beebe; Suganya Yongkiettrakul; Dehua Pei; Ming-Daw Tsai
II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides.
Journal of molecular biology 2000;302(4):927-40.
2000: Y Wei; Dehua Pei
Activation of antibacterial prodrugs by peptide deformylase.
Bioorganic & medicinal chemistry letters 2000;10(10):1073-6.
2000: KM Huntington; T Yi; Y Wei; Dehua Pei
Synthesis and antibacterial activity of peptide deformylase inhibitors.
Biochemistry 2000;39(15):4543-51.
2000: Y Zhou; X C Guo; T Yi; T Yoshimoto; Dehua Pei
Two continuous spectrophotometric assays for methionine aminopeptidase.
Analytical biochemistry 2000;280(1):159-65.
2000: Kirk D Beebe; J Shin; J Peng; Chaity Chaudhury; J Khera; Dehua Pei
Substrate recognition through a PDZ domain in tail-specific protease.
Biochemistry 2000;39(11):3149-55.
2000: PT Rajagopalan; S Grimme; Dehua Pei
Characterization of cobalt(II)-substituted peptide deformylase: function of the metal ion and the catalytic residue Glu-133.
Biochemistry 2000;39(4):779-90.
1999: KM Huntington; David L Bienvenue; Y Wei; Brian Bennett; Richard C Holz; Dehua Pei
Slow-binding inhibition of the aminopeptidase from Aeromonas proteolytica by peptide thiols: synthesis and spectroscopic characterization.
Biochemistry 1999;38(47):15587-96.
1999: X C Guo; P T Ravi Rajagopalan; Dehua Pei
A direct spectrophotometric assay for peptide deformylase.
Analytical biochemistry 1999;273(2):298-304.
1999: Bing Hao; Weimin Gong; PT Rajagopalan; Y Zhou; Dehua Pei; Michael K Chan
Structural basis for the design of antibiotics targeting peptide deformylase.
Biochemistry 1999;38(15):4712-9.
1999: Y J Hu; Y Wei; Y Zhou; PT Rajagopalan; Dehua Pei
Determination of substrate specificity for peptide deformylase through the screening of a combinatorial peptide library.
Biochemistry 1999;38(2):643-50.
1998: Kirk D Beebe; Dehua Pei
A continuous fluorimetric assay for tail-specific protease.
Analytical biochemistry 1998;263(1):51-6.
1998: Y J Hu; PT Rajagopalan; Dehua Pei
H-phosphonate derivatives as novel peptide deformylase inhibitors.
Bioorganic & medicinal chemistry letters 1998;8(18):2479-82.
1998: Y Wei; Y Yan; Dehua Pei; B Gong
A photoactivated prodrug.
Bioorganic & medicinal chemistry letters 1998;8(18):2419-22.
1998: PT Rajagopalan; Dehua Pei
Oxygen-mediated inactivation of peptide deformylase.
The Journal of biological chemistry 1998;273(35):22305-10.
1997: PT Rajagopalan; A Datta; Dehua Pei
Purification, characterization, and inhibition of peptide deformylase from Escherichia coli.
Biochemistry 1997;36(45):13910-8.
1997: Michael K Chan; Weimin Gong; PT Rajagopalan; Bing Hao; C M Tsai; Dehua Pei
Crystal structure of the Escherichia coli peptide deformylase.
Biochemistry 1997;36(45):13904-9.
1997: Y Wei; Dehua Pei
Continuous spectrophotometric assay of peptide deformylase.
Analytical biochemistry 1997;250(1):29-34.