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Hugh Pelham

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Genes & Molecular Sequences

Anatomy

Living Beings

Saccharomyces cerevisiae

Concepts & Ideas

Molecular Sequence Data

Physiology

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Co-Publications
Name
7
Nichols, Benjamin
6
Lewis, Michael
5
Siniossoglou, Symeon
4
Black, Michael
3
Nikko, Elina
3
Valdez-Taubas, Javier
3
Holthuis, JC
3
Reggiori, Fulvio
2
Wickner, William
2
Wilson, Duncan
2
Ungermann, C
2
Fridmann-Sirkis, Yael
2
Hettema, Ewald
1
Evans, Philip
1
Peak Chew, Sew-Yeu

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Publications

TOP 3
Nikko Elina; Pelham Hugh R B
Arrestin-mediated endocytosis of yeast plasma membrane transporters.
Mund Thomas; Pelham Hugh R B
Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins.
Lewis Michael J; Pelham Hugh R B
Inefficient quality control of thermosensitive proteins on the plasma membrane.

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All Publications

2009: Nikko Elina; Pelham Hugh R B
Arrestin-mediated endocytosis of yeast plasma membrane transporters.
Traffic (Copenhagen, Denmark) 2009;10(12):1856-67.
2009: Mund Thomas; Pelham Hugh R B
Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins.
EMBO reports 2009;10(5):501-7.
2009: Lewis Michael J; Pelham Hugh R B
Inefficient quality control of thermosensitive proteins on the plasma membrane.
PloS one 2009;4(4):e5038.
2008: Nikko Elina; Sullivan James A; Pelham Hugh R B
Arrestin-like proteins mediate ubiquitination and endocytosis of the yeast metal transporter Smf1.
EMBO reports 2008;9(12):1216-21.
2007: Sullivan James A; Lewis Michael J; Nikko Elina; Pelham Hugh R B
Multiple interactions drive adaptor-mediated recruitment of the ubiquitin ligase rsp5 to membrane proteins in vivo and in vitro.
Molecular biology of the cell 2007;18(7):2429-40.
2006: Pelham Hugh R B
Maturation of Golgi cisternae directly observed.
Trends in biochemical sciences 2006;31(11):601-4.
2006: Stimpson Helen E M; Lewis Michael J; Pelham Hugh R B
Transferrin receptor-like proteins control the degradation of a yeast metal transporter.
The EMBO journal 2006;25(4):662-72.
2006: Fridmann-Sirkis Yael; Kent Helen M; Lewis Michael J; Evans Philip R; Pelham Hugh R B
Structural analysis of the interaction between the SNARE Tlg1 and Vps51.
Traffic (Copenhagen, Denmark) 2006;7(2):182-90.
2005: Valdez-Taubas Javier; Pelham Hugh
Swf1-dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation.
The EMBO journal 2005;24(14):2524-32.
2004: Fridmann-Sirkis Yael; Siniossoglou Symeon; Pelham Hugh R B
TMF is a golgin that binds Rab6 and influences Golgi morphology.
BMC cell biology 2004;5():18.
2004: Pelham Hugh R B
Membrane traffic: GGAs sort ubiquitin.
Current biology : CB 2004;14(9):R357-9.
2004: Hettema Ewald H; Valdez-Taubas Javier; Pelham Hugh R B
Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins.
The EMBO journal 2004;23(6):1279-88.
2003: Valdez-Taubas Javier; Pelham Hugh R B
Slow diffusion of proteins in the yeast plasma membrane allows polarity to be maintained by endocytic cycling.
Current biology : CB 2003;13(18):1636-40.
2003: Hettema Ewald H; Lewis Michael J; Black Michael W; Pelham Hugh R B
Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes.
The EMBO journal 2003;22(3):548-57.
2002: Lewis Michael J; Pelham Hugh R B
A new yeast endosomal SNARE related to mammalian syntaxin 8.
Traffic (Copenhagen, Denmark) 2002;3(12):922-9.
2002: Siniossoglou Symeon; Pelham Hugh R B
Vps51p links the VFT complex to the SNARE Tlg1p.
The Journal of biological chemistry 2002;277(50):48318-24.
2002: Pelham Hugh R B
Insights from yeast endosomes.
Current opinion in cell biology 2002;14(4):454-62.
2002: Reggiori Fulvio; Pelham Hugh R B
A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies.
Nature cell biology 2002;4(2):117-23.
2001: Siniossoglou S; Pelham H R
An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes.
The EMBO journal 2001;20(21):5991-8.
2001: Reggiori F; Pelham H R
Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting.
The EMBO journal 2001;20(18):5176-86.
2001: Black M W; Pelham H R
Membrane traffic: how do GGAs fit in with the adaptors?
Current biology : CB 2001;11(12):R460-2.
2001: Pelham H R
SNAREs and the specificity of membrane fusion.
Trends in cell biology 2001;11(3):99-101.
2000: Reggiori F; Black M W; Pelham H R
Polar transmembrane domains target proteins to the interior of the yeast vacuole.
Molecular biology of the cell 2000;11(11):3737-49.
2000: Black M W; Pelham H R
A selective transport route from Golgi to late endosomes that requires the yeast GGA proteins.
The Journal of cell biology 2000;151(3):587-600.
2000: Pelham H R; Rothman J E
The debate about transport in the Golgi--two sides of the same coin?
Cell 2000;102(6):713-9.
2000: Siniossoglou S; Peak-Chew S Y; Pelham H R
Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p.
The EMBO journal 2000;19(18):4885-94.
2000: Siniossoglou S; Hurt E C; Pelham H R
Psr1p/Psr2p, two plasma membrane phosphatases with an essential DXDX(T/V) motif required for sodium stress response in yeast.
The Journal of biological chemistry 2000;275(25):19352-60.
2000: Pelham H
Getting stuck in the Golgi.
Traffic (Copenhagen, Denmark) 2000;1(2):191-2.
2000: Lewis M J; Nichols B J; Prescianotto-Baschong C; Riezman H; Pelham H R
Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes.
Molecular biology of the cell 2000;11(1):23-38.
2000: Pelham H R
Using sorting signals to retain proteins in endoplasmic reticulum.
Methods in enzymology 2000;327():279-83.
1999: Pelham H R
The Croonian Lecture 1999. Intracellular membrane traffic: getting proteins sorted.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1999;354(1388):1471-8.
1999: Conchon S; Cao X; Barlowe C; Pelham H R
Got1p and Sft2p: membrane proteins involved in traffic to the Golgi complex.
The EMBO journal 1999;18(14):3934-46.
1999: Pelham H R
SNAREs and the secretory pathway-lessons from yeast.
Experimental cell research 1999;247(1):1-8.
1998: Nichols B J; Holthuis J C; Pelham H R
The Sec1p homologue Vps45p binds to the syntaxin Tlg2p.
European journal of cell biology 1998;77(4):263-8.
1998: Holthuis J C; Nichols B J; Pelham H R
The syntaxin Tlg1p mediates trafficking of chitin synthase III to polarized growth sites in yeast.
Molecular biology of the cell 1998;9(12):3383-97.
1998: Wooding S; Pelham H R
The dynamics of golgi protein traffic visualized in living yeast cells.
Molecular biology of the cell 1998;9(9):2667-80.
1998: Nichols B J; Pelham H R
SNAREs and membrane fusion in the Golgi apparatus.
Biochimica et biophysica acta 1998;1404(1-2):9-31.
1998: Pelham H R
Getting through the Golgi complex.
Trends in cell biology 1998;8(1):45-9.
1998: Scheel A A; Pelham H R
Identification of amino acids in the binding pocket of the human KDEL receptor.
The Journal of biological chemistry 1998;273(4):2467-72.
1998: Holthuis J C; Nichols B J; Dhruvakumar S; Pelham H R
Two syntaxin homologues in the TGN/endosomal system of yeast.
The EMBO journal 1998;17(1):113-26.
1998: Ungermann C; Nichols B J; Pelham H R; Wickner W
A vacuolar v-t-SNARE complex, the predominant form in vivo and on isolated vacuoles, is disassembled and activated for docking and fusion.
The Journal of cell biology 1998;140(1):61-9.
1997: Pelham H R
EJCB-Lecture. SNAREs and the organization of the secretory pathway.
European journal of cell biology 1997;74(4):311-4.
1997: Lewis M J; Rayner J C; Pelham H R
A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum.
The EMBO journal 1997;16(11):3017-24.
1997: Nichols B J; Ungermann C; Pelham H R; Wickner W T; Haas A
Homotypic vacuolar fusion mediated by t- and v-SNAREs.
Nature 1997;387(6629):199-202.
1997: Rayner J C; Pelham H R
Transmembrane domain-dependent sorting of proteins to the ER and plasma membrane in yeast.
The EMBO journal 1997;16(8):1832-41.
1996: Pelham H R
The dynamic organisation of the secretory pathway.
Cell structure and function 1996;21(5):413-9.
1996: Scheel A A; Pelham H R
Purification and characterization of the human KDEL receptor.
Biochemistry 1996;35(31):10203-9.
1996: Lewis M J; Pelham H R
SNARE-mediated retrograde traffic from the Golgi complex to the endoplasmic reticulum.
Cell 1996;85(2):205-15.
1995: Pelham H R
Sorting and retrieval between the endoplasmic reticulum and Golgi apparatus.
Current opinion in cell biology 1995;7(4):530-5.
1995: Banfield D K; Lewis M J; Pelham H R
A SNARE-like protein required for traffic through the Golgi complex.
Nature 1995;375(6534):806-9.
1995: Pelham H R; Banfield D K; Lewis M J
SNAREs involved in traffic through the Golgi complex.
Cold Spring Harbor symposia on quantitative biology 1995;60():105-11.
1994: Pelham H R
About turn for the COPs?
Cell 1994;79(7):1125-7.
1994: Banfield D K; Lewis M J; Rabouille C; Warren G; Pelham H R
Localization of Sed5, a putative vesicle targeting molecule, to the cis-Golgi network involves both its transmembrane and cytoplasmic domains.
The Journal of cell biology 1994;127(2):357-71.
1994: Townsley F M; Frigerio G; Pelham H R
Retrieval of HDEL proteins is required for growth of yeast cells.
The Journal of cell biology 1994;127(1):21-8.
1994: Townsley F M; Pelham H R
The KKXX signal mediates retrieval of membrane proteins from the Golgi to the ER in yeast.
European journal of cell biology 1994;64(1):211-6.
1994: Hardwick K G; Pelham H R
SED6 is identical to ERG6, and encodes a putative methyltransferase required for ergosterol synthesis.
Yeast (Chichester, England) 1994;10(2):265-9.
1993: Pelham H R; Munro S
Sorting of membrane proteins in the secretory pathway.
Cell 1993;75(4):603-5.
1993: Frigerio G; Pelham H R
A Saccharomyces cerevisiae cyclophilin resident in the endoplasmic reticulum.
Journal of molecular biology 1993;233(1):183-8.
1993: Townsley F M; Wilson D W; Pelham H R
Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport.
The EMBO journal 1993;12(7):2821-9.
1993: Sweet D J; Pelham H R
The TIP1 gene of Saccharomyces cerevisiae encodes an 80 kDa cytoplasmic protein that interacts with the cytoplasmic domain of Sec20p.
The EMBO journal 1993;12(7):2831-40.
1993: Pelham H R
Is epimorphin involved in vesicular transport?
Cell 1993;73(3):425-6.
1993: Wilson D W; Lewis M J; Pelham H R
pH-dependent binding of KDEL to its receptor in vitro.
The Journal of biological chemistry 1993;268(10):7465-8.
1992: Hardwick K G; Pelham H R
SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex.
The Journal of cell biology 1992;119(3):513-21.
1992: Hardwick K G; Boothroyd J C; Rudner A D; Pelham H R
Genes that allow yeast cells to grow in the absence of the HDEL receptor.
The EMBO journal 1992;11(11):4187-95.
1992: Lewis M J; Pelham H R
Sequence of a second human KDEL receptor.
Journal of molecular biology 1992;226(4):913-6.
1992: Semenza J C; Pelham H R
Changing the specificity of the sorting receptor for luminal endoplasmic reticulum proteins.
Journal of molecular biology 1992;224(1):1-5.
1992: Sweet D J; Pelham H R
The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system.
The EMBO journal 1992;11(2):423-32.
1992: Lewis M J; Pelham H R
Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum.
Cell 1992;68(2):353-64.
1991: Pelham H R
Multiple targets for brefeldin A.
Cell 1991;67(3):449-51.
1991: Pelham H R
Recycling of proteins between the endoplasmic reticulum and Golgi complex.
Current opinion in cell biology 1991;3(4):585-91.
1991: Jakobsen B K; Pelham H R
A conserved heptapeptide restrains the activity of the yeast heat shock transcription factor.
The EMBO journal 1991;10(2):369-75.
1990: Lewis M J; Pelham H R
The sequence of the Kluyveromyces lactis BiP gene.
Nucleic acids research 1990;18(21):6438.
1990: Lewis M J; Pelham H R
A human homologue of the yeast HDEL receptor.
Nature 1990;348(6297):162-3.
1990: Dean N; Pelham H R
Recycling of proteins from the Golgi compartment to the ER in yeast.
The Journal of cell biology 1990;111(2):369-77.
1990: Lewis M J; Sweet D J; Pelham H R
The ERD2 gene determines the specificity of the luminal ER protein retention system.
Cell 1990;61(7):1359-63.
1990: Semenza J C; Hardwick K G; Dean N; Pelham H R
ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway.
Cell 1990;61(7):1349-57.
1990: Hardwick K G; Pelham H R
ERS1 a seven transmembrane domain protein from Saccharomyces cerevisiae.
Nucleic acids research 1990;18(8):2177.
1990: Hardwick K G; Lewis M J; Semenza J; Dean N; Pelham H R
ERD1, a yeast gene required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus.
The EMBO journal 1990;9(3):623-30.
1989: Pelham H R
Heat shock and the sorting of luminal ER proteins.
The EMBO journal 1989;8(11):3171-6.
1988: Sorger P K; Pelham H R
Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation.
Cell 1988;54(6):855-64.
1988: Pelham H R; Hardwick K G; Lewis M J
Sorting of soluble ER proteins in yeast.
The EMBO journal 1988;7(6):1757-62.
1988: Pelham H R
Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment.
The EMBO journal 1988;7(4):913-8.
1987: Sorger P K; Pelham H R
Purification and characterization of a heat-shock element binding protein from yeast.
The EMBO journal 1987;6(10):3035-41.
1987: Sorger P K; Lewis M J; Pelham H R
Heat shock factor is regulated differently in yeast and HeLa cells.
Nature 1987;329(6134):81-4.
1987: Sorger P K; Pelham H R
Cloning and expression of a gene encoding hsc73, the major hsp70-like protein in unstressed rat cells.
The EMBO journal 1987;6(4):993-8.
1987: Sorger P K; Pelham H R
The glucose-regulated protein grp94 is related to heat shock protein hsp90.
Journal of molecular biology 1987;194(2):341-4.

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