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Luca Pellegrini

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D V Jeyaraju; H M McBride; R B Hill; Luca Pellegrini
Structural and mechanistic basis of Parl activity and regulation.
D V Jeyaraju; G Cisbani; Olga Martins de Brito; E V Koonin; Luca Pellegrini
Hax1 lacks BH modules and is peripherally associated to heavy membranes: implications for Omi/HtrA2 and PARL activity in the regulation of mitochondrial stress and apoptosis.
Danny V Jeyaraju; Liqun Xu; Marie-Claude Letellier; Sirisha Bandaru; rodolfo zunino; Eric A Berg; Heidi McBride; Luca Pellegrini
Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology.

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All Publications

2011: D V Jeyaraju; H M McBride; R B Hill; Luca Pellegrini
Structural and mechanistic basis of Parl activity and regulation.
Cell death and differentiation 2011;18(9):1531-9.
2009: D V Jeyaraju; G Cisbani; Olga Martins de Brito; E V Koonin; Luca Pellegrini
Hax1 lacks BH modules and is peripherally associated to heavy membranes: implications for Omi/HtrA2 and PARL activity in the regulation of mitochondrial stress and apoptosis.
Cell death and differentiation 2009;16(12):1622-9.
2006: Danny V Jeyaraju; Liqun Xu; Marie-Claude Letellier; Sirisha Bandaru; rodolfo zunino; Eric A Berg; Heidi McBride; Luca Pellegrini
Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(49):18562-7.
2006: Sara Cipolat; T Rudka; Dieter Hartmann; Veronica Costa; Lutgarde Serneels; Katleen Craessaerts; Kristine Metzger; Christian Frezza; Willem ANNAERT; Luciano D'Adamio; Carmen Derks; Tim Dejaegere; Luca Pellegrini; Rudi D'Hooge; LUCA SCORRANO; Bart De Strooper
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling.
Cell 2006;126(1):163-75.
2004: Attila Sík; Brent J Passer; Eugene V Koonin; Luca Pellegrini
Self-regulated cleavage of the mitochondrial intramembrane-cleaving protease PARL yields Pbeta, a nuclear-targeted peptide.
The Journal of biological chemistry 2004;279(15):15323-9.
2003: Eugene V Koonin; Kira S Makarova; Igor Rogozin; Laetitia Davidovic; Marie-Claude Letellier; Luca Pellegrini
The rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers.
Genome biology 2003;4(3):R19.
2002: Roberta Borghi; Luca Pellegrini; Emanuela Lacaná; Alberto Diaspro; MARIA ADELAIDE PRONZATO; Antonella Vitali; Roberta Roncarati; Paola Strocchi; Damiano Zaccheo; Luciano D'Adamio; Massimo Tabaton
Neuronal apoptosis is accompanied by amyloid beta-protein accumulation in the endoplasmic reticulum.
Journal of Alzheimer's disease : JAD 2002;4(1):31-7.
2000: Brent J Passer; Luca Pellegrini; Claudio Russo; Richard Siegel; M J Lenardo; G Schettini; M Bachmann; Massimo Tabaton; Luciano D'Adamio
Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.
Journal of Alzheimer's disease : JAD 2000;2(3-4):289-301.
1999: Brent J Passer; Luca Pellegrini; Pasquale Vito; J. Kelly Ganjei; Luciano D'Adamio
Interaction of Alzheimer's presenilin-1 and presenilin-2 with Bcl-X(L). A potential role in modulating the threshold of cell death.
The Journal of biological chemistry 1999;274(34):24007-13.
1999: Luca Pellegrini; Brent J Passer; Massimo Tabaton; J. Kelly Ganjei; Luciano D'Adamio
Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8.
The Journal of biological chemistry 1999;274(30):21011-6.
1999: Pasquale Vito; Luca Pellegrini; C Guiet; Luciano D'Adamio
Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction.
The Journal of biological chemistry 1999;274(3):1533-40.