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Jerry Pelletier

Research Profile

Physiology

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TOP 3
John R Mills; Hengli Tang; Maria Zannis-Hadjopoulos; Domenic Di Paola; Frank Grosse; Ola Larsson; Teresa Lee; Scott W Lowe; Abba Malina; Cornelius Miething; Jerry Pelletier
RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.
Z Nasr; John A Porco; Francis Robert; William J Muller; Jerry Pelletier
eIF4F suppression in breast cancer affects maintenance and progression.
Zeina Nasr; Jerry Pelletier
Tumor progression and metastasis: role of translational deregulation.

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All Publications

2013: John R Mills; Hengli Tang; Maria Zannis-Hadjopoulos; Domenic Di Paola; Frank Grosse; Ola Larsson; Teresa Lee; Scott W Lowe; Abba Malina; Cornelius Miething; Jerry Pelletier
RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.
Blood 2013;121(17):3402-12.
2013: Z Nasr; John A Porco; Francis Robert; William J Muller; Jerry Pelletier
eIF4F suppression in breast cancer affects maintenance and progression.
Oncogene 2013;32(7):861-71.
2012: Zeina Nasr; Jerry Pelletier
Tumor progression and metastasis: role of translational deregulation.
Anticancer research 2012;32(8):3077-84.
2012: Gabriela Galicia-Vázquez; Aouod Quang Agenor; Regina Cencic; Francis Robert; Jerry Pelletier
A cellular response linking eIF4AI activity to eIF4AII transcription.
RNA (New York, N.Y.) 2012;18(7):1373-84.
2012: Yingjie Sun; Evrim Atas; Lisa Lindqvist; Jerry Pelletier; Nahum Sonenberg; Amit Meller
The eukaryotic initiation factor eIF4H facilitates loop-binding, repetitive RNA unwinding by the eIF4A DEAD-box helicase.
Nucleic acids research 2012;40(13):6199-207.
2012: Chen-Ju Lin; Scott W Lowe; Zeina Nasr; John A Porco; Prem K Premsrirut; Yoshitaka Hippo; Jerry Pelletier
Targeting synthetic lethal interactions between Myc and the eIF4F complex impedes tumorigenesis.
Cell reports 2012;1(4):325-33.
2012: Abba Malina; John R Mills; Jerry Pelletier
Emerging therapeutics targeting mRNA translation.
Cold Spring Harbor perspectives in biology 2012;4(4):a012377.
2012: Francis Robert; Michel L Tremblay; Dantong Wang; Simon S Wing; Aouod Agenor; Regina Cencic; Sergio DiMarco; Imed-Eddine Gallouzi; Siegfried Hekimi; John R Mills; Jerry Pelletier
Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival.
Cancer research 2012;72(3):747-56.
2012: Regina Cencic; Gabriela Galicia-Vázquez; Jerry Pelletier
Inhibitors of translation targeting eukaryotic translation initiation factor 4A.
Methods in enzymology 2012;511():437-61.
2012: John R Mills; Abba Malina; Jerry Pelletier
Inhibiting mitochondrial-dependent proteolysis of Mcl-1 promotes resistance to DNA damage.
Cell cycle (Georgetown, Tex.) 2012;11(1):88-98.
2011: Alexander S Wahba; Fereshteh Azizi; Claire Brown; Marilyn Carrier; Glen F Deleavey; Alan M Gewirtz; Robert H E Hudson; Anna Kalota; Jerry Pelletier; Francis Robert; Masad J Damha
Phenylpyrrolocytosine as an unobtrusive base modification for monitoring activity and cellular trafficking of siRNA.
ACS chemical biology 2011;6(9):912-9.
2011: Dima Kozakov; Jerry Pelletier; Adrian Whitty; Dmitri Beglov; Ryan Brenke; Regina Cencic; Gwo-Yu Chuang; Laurie E Grove; David R Hall; Sandor Vajda
Structural conservation of druggable hot spots in protein-protein interfaces.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(33):13528-33.
2011: Kontham Ravindar; Maddi Sridhar Reddy; Lisa Lindqvist; Jerry Pelletier; Pierre Deslongchamps
Synthesis of the antiproliferative agent hippuristanol and its analogues via Suárez cyclizations and Hg(II)-catalyzed spiroketalizations.
The Journal of organic chemistry 2011;76(5):1269-84.
2011: Regina Cencic; David R Hall; Francis Robert; Yuhong Du; Jaeki Min; Lian Li; Min Qui; Iestyn Lewis; Serdar Kurtkaya; ray dingledine; Haian Fu; Dima Kozakov; Sandor Vajda; Jerry Pelletier
Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(3):1046-51.
2011: Abba Malina; Regina Cencic; Jerry Pelletier
Targeting translation dependence in cancer.
Oncotarget 2011;2(1-2):76-88.
2010: François Bélanger; Janusz Stepinski; Edward Darzynkiewicz; Jerry Pelletier
Characterization of hMTr1, a human Cap1 2'-O-ribose methyltransferase.
The Journal of biological chemistry 2010;285(43):33037-44.
2010: Kontham Ravindar; Maddi Sridhar Reddy; Lisa Lindqvist; Jerry Pelletier; Pierre Deslongchamps
Efficient synthetic approach to potent antiproliferative agent hippuristanol via Hg(II)-catalyzed spiroketalization.
Organic letters 2010;12(19):4420-3.
2010: Nathalie Malo; James A Hanley; Graeme Carlile; Jing Liu; Jerry Pelletier; David Thomas; Robert Nadon
Experimental design and statistical methods for improved hit detection in high-throughput screening.
Journal of biomolecular screening 2010;15(8):990-1000.
2010: Regina Cencic; Marilyn Carrier; Amanda Trnkus; John A Porco; Mark Minden; Jerry Pelletier
Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells.
Leukemia research 2010;34(4):535-41.
2009: Mark Livingstone; Ola Larsson; Rami Sukarieh; Jerry Pelletier; Nahum Sonenberg
A chemical genetic screen for mTOR pathway inhibitors based on 4E-BP-dependent nuclear accumulation of eIF4E.
Chemistry & biology 2009;16(12):1240-9.
2009: Lisa Lindqvist; Jerry Pelletier
Inhibitors of translation initiation as cancer therapeutics.
Future medicinal chemistry 2009;1(9):1709-22.
2009: Francis Robert; Jerry Pelletier
Translation initiation: a critical signalling node in cancer.
Expert opinion on therapeutic targets 2009;13(11):1279-93.
2009: Chen-Ju Lin; Abba Malina; Jerry Pelletier
c-Myc and eIF4F constitute a feedforward loop that regulates cell growth: implications for anticancer therapy.
Cancer research 2009;69(19):7491-4.
2009: Francis Robert; Chris Williams; Yifei Yan; Elizabeth Donohue; Regina Cencic; Stephen K Burley; Jerry Pelletier
Blocking UV-induced eIF2alpha phosphorylation with small molecule inhibitors of GCN2.
Chemical biology & drug design 2009;74(1):57-67.
2009: Chen-Ju Lin; Rami Sukarieh; Jerry Pelletier
Silibinin inhibits translation initiation: implications for anticancer therapy.
Molecular cancer therapeutics 2009;8(6):1606-12.
2009: Mohammed Dehbi; Greg Moeck; Francis F Arhin; Pascale Bauda; Dominique Bergeron; Tony Kwan; Jing Liu; John McCarty; Michael Dubow; Jerry Pelletier
Inhibition of transcription in Staphylococcus aureus by a primary sigma factor-binding polypeptide from phage G1.
Journal of bacteriology 2009;191(12):3763-71.
2009: Sophie Mokas; John R Mills; Cristina Garreau; Marie-Josée Fournier; Francis Robert; Prabhat Arya; Randal J Kaufman; Jerry Pelletier; Rachid Mazroui
Uncoupling stress granule assembly and translation initiation inhibition.
Molecular biology of the cell 2009;20(11):2673-83.
2009: Michel Gravel; Francis Robert; Vicky Kottis; Imed-Eddine Gallouzi; Jerry Pelletier; Peter E Braun
2',3'-Cyclic nucleotide 3'-phosphodiesterase: a novel RNA-binding protein that inhibits protein synthesis.
Journal of neuroscience research 2009;87(5):1069-79.
2009: John A Beutler; Moon-Il Kang; Francis Robert; Jason A Clement; Jerry Pelletier; Nancy H Colburn; Tawnya C McKee; Ekaterina Goncharova; James B McMahon; Curtis J Henrich
Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition.
Journal of natural products 2009;72(3):503-6.
2009: Francis Robert; Marilyn Carrier; Svea Rawe; Samuel Chen; Scott W Lowe; Jerry Pelletier
Altering chemosensitivity by modulating translation elongation.
PloS one 2009;4(5):e5428.
2009: Regina Cencic; Marilyn Carrier; Gabriela Galicia-Vázquez; Marie-Eve Bordeleau; Rami Sukarieh; Annie Bourdeau; Brigitte Brem; Jose Teodoro; Harald Greger; Michel L Tremblay; John A Porco; Jerry Pelletier
Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol.
PloS one 2009;4(4):e5223.
2009: Gabriela Galicia-Vázquez; Lisa Lindqvist; Xiaofeng Wang; Isabelle Harvey; Jing Liu; Jerry Pelletier
High-throughput assays probing protein-RNA interactions of eukaryotic translation initiation factors.
Analytical biochemistry 2009;384(1):180-8.
2008: John R Mills; Yoshitaka Hippo; Francis Robert; Samuel M H Chen; Abba Malina; Chen-Ju Lin; Ulrike Trojahn; Hans-Guido Wendel; Al Charest; Roderick T Bronson; Scott C Kogan; Robert Nadon; David E Housman; Scott W Lowe; Jerry Pelletier
mTORC1 promotes survival through translational control of Mcl-1.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10853-8.
2008: Chen-Ju Lin; Regina Cencic; John R Mills; Francis Robert; Jerry Pelletier
c-Myc and eIF4F are components of a feedforward loop that links transcription and translation.
Cancer research 2008;68(13):5326-34.
2008: Marie-Eve Bordeleau; Francis Robert; Baudouin Gerard; Lisa Lindqvist; Samuel M H Chen; Hans-Guido Wendel; Brigitte Brem; Harald Greger; Scott W Lowe; John A Porco; Jerry Pelletier
Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model.
The Journal of clinical investigation 2008;118(7):2651-60.
2008: Liwei Rong; Mark Livingstone; Rami Sukarieh; Emmanuel Petroulakis; Anne-Claude Gingras; Katherine Crosby; Bradley Smith; Roberto D Polakiewicz; Jerry Pelletier; Maria A Ferraiuolo; Nahum Sonenberg
Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs.
RNA (New York, N.Y.) 2008;14(7):1318-27.
2008: Lisa Lindqvist; Hiroaki Imataka; Jerry Pelletier
Cap-dependent eukaryotic initiation factor-mRNA interactions probed by cross-linking.
RNA (New York, N.Y.) 2008;14(5):960-9.
2008: Lisa Lindqvist; Monika Oberer; Mikhail Reibarkh; Regina Cencic; Marie-Eve Bordeleau; Emily Vogt; Assen Marintchev; Junichi Tanaka; Francois Fagotto; Michael Altmann; Gerhard Wagner; Jerry Pelletier
Selective pharmacological targeting of a DEAD box RNA helicase.
PloS one 2008;3(2):e1583.
2007: Shirin Kazemi; Zineb Mounir; Dionissios Baltzis; Jennifer F Raven; Shuo Wang; Jothi-Latha Krishnamoorthy; Olivier Pluquet; Jerry Pelletier; Antonis E Koromilas
A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway.
Molecular biology of the cell 2007;18(9):3635-44.
2007: Mauro Costa-Mattioli; Delphine Gobert; Elad Stern; Karine Gamache; Rodney Colina; Claudio Cuello; Wayne S Sossin; Randal J Kaufman; Jerry Pelletier; Kobi Rosenblum; Kresimir Krnjević; Jean-Claude Lacaille; Karim Nader; Nahum Sonenberg
eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory.
Cell 2007;129(1):195-206.
2007: Regina Cencic; Yifei Yan; Jerry Pelletier
Homogenous time resolved fluorescence assay to identify modulators of cap-dependent translation initiation.
Combinatorial chemistry & high throughput screening 2007;10(3):181-8.
2007: Regina Cencic; Francis Robert; Jerry Pelletier
Identifying small molecule inhibitors of eukaryotic translation initiation.
Methods in enzymology 2007;431():269-302.
2007: Jonathan K Watts; Niloufar Choubdar; Kashinath Sadalapure; Francis Robert; Alexander S Wahba; Jerry Pelletier; B Mario Pinto; Masad J Damha
2'-fluoro-4'-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity.
Nucleic acids research 2007;35(5):1441-51.
2006: Marie-Eve Bordeleau; Regina Cencic; Lisa Lindqvist; Monika Oberer; Peter T Northcote; Gerhard Wagner; Jerry Pelletier
RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation.
Chemistry & biology 2006;13(12):1287-95.
2006: Adam Belley; Mario Callejo; Francis Arhin; Mohammed Dehbi; Ibtihal Fadhil; Jing Liu; Geoffrey McKay; Ramakrishnan Srikumar; Pascale Bauda; Dominique Bergeron; Nhuan Ha; Michael DuBow; Philippe Gros; Jerry Pelletier; Greg Moeck
Competition of bacteriophage polypeptides with native replicase proteins for binding to the DNA sliding clamp reveals a novel mechanism for DNA replication arrest in Staphylococcus aureus.
Molecular microbiology 2006;62(4):1132-43.
2006: Francis Robert; Lee Kapp; Shakila N Khan; Michael Acker; Sarah E Kolitz; Shirin Kazemi; Randal J Kaufman; William C Merrick; Antonis E Koromilas; Jon R Lorsch; Jerry Pelletier
Initiation of protein synthesis by hepatitis C virus is refractory to reduced eIF2.GTP.Met-tRNA(i)(Met) ternary complex availability.
Molecular biology of the cell 2006;17(11):4632-44.
2006: Rachid Mazroui; Rami Sukarieh; Marie-Eve Bordeleau; Randal J Kaufman; Peter T Northcote; Junichi Tanaka; Imed-Eddine Gallouzi; Jerry Pelletier
Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2alpha phosphorylation.
Molecular biology of the cell 2006;17(10):4212-9.
2006: Yasmin Chaudhry; Arabinda Nayak; Marie-Eve Bordeleau; Junichi Tanaka; Jerry Pelletier; Graham J Belsham; Lisa O Roberts; Ian G Goodfellow
Caliciviruses differ in their functional requirements for eIF4F components.
The Journal of biological chemistry 2006;281(35):25315-25.
2006: Francis Arhin; Odette Bélanger; Stéphane Ciblat; Mohammed Dehbi; Daniel Delorme; Evelyne Dietrich; Dilip Dixit; Yanick Lafontaine; Dario Lehoux; Jing Liu; Geoffrey McKay; Greg Moeck; Ranga Reddy; Yannick Rose; Ramakrishnan Srikumar; Kelly S E Tanaka; Daniel M Williams; Philippe Gros; Jerry Pelletier; Thomas R Parr; Adel Rafai Far
A new class of small molecule RNA polymerase inhibitors with activity against rifampicin-resistant Staphylococcus aureus.
Bioorganic & medicinal chemistry 2006;14(17):5812-32.
2006: Elena Torban; Alison Dziarmaga; Diana M Iglesias; Lee Lee Chu; Tatiana Vassilieva; Melissa Little; Michael Eccles; Maria Teresa Discenza; Jerry Pelletier; Paul Goodyer
PAX2 activates WNT4 expression during mammalian kidney development.
The Journal of biological chemistry 2006;281(18):12705-12.
2006: Francis Robert; Hong Qing Gao; Marwa Donia; William C Merrick; Mark T Hamann; Jerry Pelletier
Chlorolissoclimides: new inhibitors of eukaryotic protein synthesis.
RNA (New York, N.Y.) 2006;12(5):717-25.
2006: Marie-Eve Bordeleau; Ayaka Mori; Monika Oberer; Lisa Lindqvist; Louisa S Chard; Tatsuo Higa; Graham J Belsham; Gerhard Wagner; Junichi Tanaka; Jerry Pelletier
Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A.
Nature chemical biology 2006;2(4):213-20.
2006: Louisa S Chard; Marie-Eve Bordeleau; Jerry Pelletier; Junichi Tanaka; Graham J Belsham
Hepatitis C virus-related internal ribosome entry sites are found in multiple genera of the family Picornaviridae.
The Journal of general virology 2006;87(Pt 4):927-36.
2006: Geoffrey McKay; Ranga Reddy; Francis Arhin; Adam Belley; Dario Lehoux; Greg Moeck; Ingrid Sarmiento; Thomas R Parr; Philippe Gros; Jerry Pelletier; Adel Rafai Far
Triaminotriazine DNA helicase inhibitors with antibacterial activity.
Bioorganic & medicinal chemistry letters 2006;16(5):1286-90.
2006: Eun-Hee Park; Joseph M Lee; Jerry Pelletier
The Tie2 5' untranslated region is inhibitory to 5' end-mediated translation initiation.
FEBS letters 2006;580(5):1309-19.
2006: Nathalie Malo; James A Hanley; Sonia Cerquozzi; Jerry Pelletier; Robert Nadon
Statistical practice in high-throughput screening data analysis.
Nature biotechnology 2006;24(2):167-75.
2006: Tony Kwan; Jing Liu; Michael DuBow; Philippe Gros; Jerry Pelletier
Comparative genomic analysis of 18 Pseudomonas aeruginosa bacteriophages.
Journal of bacteriology 2006;188(3):1184-7.
2005: Dirk Prawitt; Thorsten Enklaar; Barbara Gärtner-Rupprecht; Christian Spangenberg; Ekkehart U Lausch; Dirk Reutzel; Stephan Fees; Maria Korzon; Izabela Brozek; Janusz Limon; David E Housman; Jerry Pelletier; Bernhard Zabel
Microdeletion and IGF2 loss of imprinting in a cascade causing Beckwith-Wiedemann syndrome with Wilms' tumor.
Nature genetics 2005;37(8):785-6; author reply 786-7.
2005: Yifei Yan; Yuri V Svitkin; Joseph M Lee; Martin Bisaillon; Jerry Pelletier
Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap.
RNA (New York, N.Y.) 2005;11(8):1238-44.
2005: Marie-Eve Bordeleau; James Matthews; Joanna M Wojnar; Lisa Lindqvist; Olivia Novac; Eckhard Jankowsky; Nahum Sonenberg; Peter T Northcote; Paul Teesdale-Spittle; Jerry Pelletier
Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(30):10460-5.
2005: Eun-Hee Park; Joseph M Lee; Jaime D Blais; John C Bell; Jerry Pelletier
Internal translation initiation mediated by the angiogenic factor Tie2.
The Journal of biological chemistry 2005;280(22):20945-53.
2005: Tony Kwan; Jing Liu; Michael DuBow; Philippe Gros; Jerry Pelletier
The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(14):5174-9.
2005: Dirk Prawitt; Thorsten Enklaar; Barbara Gärtner-Rupprecht; Christian Spangenberg; Monika Oswald; Ekkehart U Lausch; Peter Schmidtke; Dirk Reutzel; Stephan Fees; Rob Lucito; Maria Korzon; Izabela Brozek; Janusz Limon; David E Housman; Jerry Pelletier; Bernhard Zabel
Microdeletion of target sites for insulator protein CTCF in a chromosome 11p15 imprinting center in Beckwith-Wiedemann syndrome and Wilms' tumor.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(11):4085-90.
2005: Abba Malina; Shakila Khan; Coby B Carlson; Yuri V Svitkin; Isabelle Harvey; Nahum Sonenberg; Peter A Beal; Jerry Pelletier
Inhibitory properties of nucleic acid-binding ligands on protein synthesis.
FEBS letters 2005;579(1):79-89.
2004: Bing Wang; Jerry Pelletier; Michel J Massaad; Annette Herscovics; Gordon C Shore
The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B.
Molecular and cellular biology 2004;24(7):2767-78.
2004: Jenny Chan; Shakila N Khan; Isabelle Harvey; William C Merrick; Jerry Pelletier
Eukaryotic protein synthesis inhibitors identified by comparison of cytotoxicity profiles.
RNA (New York, N.Y.) 2004;10(3):528-43.
2004: Maria Teresa Discenza; Darryl Vaz; John A Hassell; Jerry Pelletier
Activation of the WT1 tumor suppressor gene promoter by Pea3.
FEBS letters 2004;560(1-3):183-91.
2004: Maria Teresa Discenza; Jerry Pelletier
Insights into the physiological role of WT1 from studies of genetically modified mice.
Physiological genomics 2004;16(3):287-300.
2004: Jing Liu; Mohammed Dehbi; Greg Moeck; Francis Arhin; Pascale Bauda; Dominique Bergeron; Mario Callejo; Vincent Ferretti; Nhuan Ha; Tony Kwan; John McCarty; Ramakrishnan Srikumar; Dan Williams; Jinzi J Wu; Philippe Gros; Jerry Pelletier; Michael DuBow
Antimicrobial drug discovery through bacteriophage genomics.
Nature biotechnology 2004;22(2):185-91.
2004: Olivia Novac; Anne-Sophie Guenier; Jerry Pelletier
Inhibitors of protein synthesis identified by a high throughput multiplexed translation screen.
Nucleic acids research 2004;32(3):902-15.
2003: Maria Teresa Discenza; Shujie He; Tae Ho Lee; Lee Lee Chu; Brad Bolon; Paul Goodyer; Michael Eccles; Jerry Pelletier
WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2.
Oncogene 2003;22(50):8145-55.
2002: Joseph Lee; Eun Hee Park; Graeme Couture; Isabelle Harvey; Philippe Garneau; Jerry Pelletier
An upstream open reading frame impedes translation of the huntingtin gene.
Nucleic acids research 2002;30(23):5110-9.
2002: Tae Ho Lee; Shelly Lwu; Jungho Kim; Jerry Pelletier
Inhibition of Wilms tumor 1 transactivation by bone marrow zinc finger 2, a novel transcriptional repressor.
The Journal of biological chemistry 2002;277(47):44826-37.
2002: Marjolaine Carriere; Veerappan Vijayabaskar; Drew J Applefield; Isabelle Harvey; Philippe Garneau; Jon R Lorsch; Aviva Lapidot; Jerry Pelletier
Inhibition of protein synthesis by aminoglycoside-arginine conjugates.
RNA (New York, N.Y.) 2002;8(10):1267-79.
2002: Jie Cai; Roni Daoud; Omar Salem Alqawi; Elias Georges; Jerry Pelletier; Philippe Gros
Nucleotide binding and nucleotide hydrolysis properties of the ABC transporter MRP6 (ABCC6).
Biochemistry 2002;41(25):8058-67.
2002: Isabelle Harvey; Philippe Garneau; Jerry Pelletier
Inhibition of translation by RNA-small molecule interactions.
RNA (New York, N.Y.) 2002;8(4):452-63.
2002: Isabelle Harvey; Philippe Garneau; Jerry Pelletier
Forced engagement of a RNA/protein complex by a chemical inducer of dimerization to modulate gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):1882-7.
2001: Tae Ho Lee; Jerry Pelletier
Functional characterization of WT1 binding sites within the human vitamin D receptor gene promoter.
Physiological genomics 2001;7(2):187-200.
2001: M Das; C B Burge; E Park; J Colinas; Jerry Pelletier
Assessment of the total number of human transcription units.
Genomics 2001;77(1-2):71-8.
2001: M Das; I Harvey; Lee Lee Chu; M Sinha; Jerry Pelletier
Full-length cDNAs: more than just reaching the ends.
Physiological genomics 2001;6(2):57-80.
2000: M Das; H Sakul; J Kong; G M Acland; Jerry Pelletier
A set of canine interrepeat sequence PCR markers for high-throughput genotyping.
Physiological genomics 2000;4(1):13-24.
2000: J Kim; Joseph M Lee; Philip E Branton; Jerry Pelletier
Modulation of EWS/WT1 activity by the v-Src protein tyrosine kinase.
FEBS letters 2000;474(2-3):121-8.
2000: Dirk Prawitt; Thorsten Enklaar; G Klemm; B Gärtner; Christian Spangenberg; Andreas Winterpacht; Michael J Higgins; Jerry Pelletier; Bernhard Zabel
Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression.
Human molecular genetics 2000;9(2):203-16.
2000: P Moffett; Jerry Pelletier
Different transcriptional properties of mSim-1 and mSim-2.
FEBS letters 2000;466(1):80-6.
1999: Jungho Kim; J M Lee; Philip E Branton; Jerry Pelletier
Modification of EWS/WT1 functional properties by phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14300-5.
1999: J Kim; Jerry Pelletier
Molecular genetics of chromosome translocations involving EWS and related family members.
Physiological genomics 1999;1(3):127-38.
1999: Tae Ho Lee; P Moffett; Jerry Pelletier
The Wilms' tumor suppressor gene (wt1) product represses different functional classes of transcriptional activation domains.
Nucleic acids research 1999;27(14):2889-97.
1999: Jungho Kim; Dirk Prawitt; Nabeel Bardeesy; Elena Torban; C Vicaner; Paul Goodyer; Bernhard Zabel; Jerry Pelletier
The Wilms' tumor suppressor gene (wt1) product regulates Dax-1 gene expression during gonadal differentiation.
Molecular and cellular biology 1999;19(3):2289-99.
1998: M Reece; Dirk Prawitt; J Landers; C Kast; Philippe Gros; David E Housman; Bernhard Zabel; Jerry Pelletier
Functional characterization of ORCTL2--an organic cation transporter expressed in the renal proximal tubules.
FEBS letters 1998;433(3):245-50.
1998: Lee Lee Chu; Gerard Rutteman; J M Kong; Mohammad Hossein Ghahremani; M Schmeing; W Misdorp; Evert van Garderen; Jerry Pelletier
Genomic organization of the canine p53 gene and its mutational status in canine mammary neoplasia.
Breast cancer research and treatment 1998;50(1):11-25.
1998: M Dehbi; John Hiscott; Jerry Pelletier
Activation of the wt1 Wilms' tumor suppressor gene by NF-kappaB.
Oncogene 1998;16(16):2033-9.
1998: Jungho Kim; K Lee; Jerry Pelletier
The desmoplastic small round cell tumor t(11;22) translocation produces EWS/WT1 isoforms with differing oncogenic properties.
Oncogene 1998;16(15):1973-9.
1998: Paul Roy Cooper; NJ Smilinich; CD Day; Norma J Nowak; LH Reid; R S Pearsall; M Reece; Dirk Prawitt; J Landers; David E Housman; Andreas Winterpacht; Bernhard Zabel; Jerry Pelletier; Bernard E Weissman; TB Shows; Michael J Higgins
Divergently transcribed overlapping genes expressed in liver and kidney and located in the 11p15.5 imprinted domain.
Genomics 1998;49(1):38-51.
1998: Nabeel Bardeesy; Jerry Pelletier
Overlapping RNA and DNA binding domains of the wt1 tumor suppressor gene product.
Nucleic acids research 1998;26(7):1784-92.
1998: Jungho Kim; K Lee; Jerry Pelletier
The DNA binding domains of the WT1 tumor suppressor gene product and chimeric EWS/WT1 oncoprotein are functionally distinct.
Oncogene 1998;16(8):1021-30.
1998: M Das; Lee Lee Chu; Mohammad Hossein Ghahremani; T Abrams-Ogg; Marie-Sylvie Roy; David E Housman; Jerry Pelletier
Characterization of an abundant short interspersed nuclear element (SINE) present in Canis familiaris.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(1):64-9.
1997: Maria Teresa Discenza; M Dehbi; Jerry Pelletier
Overlapping DNA recognition motifs between Sp1 and a novel trans-acting factor within the wt1 tumour suppressor gene promoter.
Nucleic acids research 1997;25(21):4314-22.
1997: Elena Torban; Jerry Pelletier; Paul Goodyer
F329L polymorphism in the human PAX8 gene.
American journal of medical genetics 1997;72(2):186-7.
1997: P Rodriguez; D Munroe; Dirk Prawitt; Lee Lee Chu; E Bric; Jungho Kim; LH Reid; C Davies; H Nakagama; R Loebbert; Andreas Winterpacht; M J Petruzzi; Michael J Higgins; Norma J Nowak; G Evans; TB Shows; Bernard E Weissman; Bernhard Zabel; David E Housman; Jerry Pelletier
Functional characterization of human nucleosome assembly protein-2 (NAP1L4) suggests a role as a histone chaperone.
Genomics 1997;44(3):253-65.
1997: C Vicanek; E Ferretti; Cynthia G Goodyer; Elena Torban; P Moffett; Jerry Pelletier; Paul Goodyer
Regulation of renal EGF receptor expression is normal in Denys-Drash syndrome.
Kidney international 1997;52(3):614-9.
1997: P Moffett; M Reece; Jerry Pelletier
The murine Sim-2 gene product inhibits transcription by active repression and functional interference.
Molecular and cellular biology 1997;17(9):4933-47.
1996: Mohammad Hossein Ghahremani; C B Chan; Tzvy Bistritzer; M M Aladjem; M Tieder; Jerry Pelletier
A novel mutation H373Y in the Wilms' tumor suppressor gene, WT1, associated with Denys-Drash syndrome.
Human heredity 1996;46(6):336-8.
1996: Frederick P Li; Norman E Breslow; J M Morgan; Mohammad Hossein Ghahremani; G A Miller; Paul E Grundy; D M Green; Lisa Diller; Jerry Pelletier
Germline WT1 mutations in Wilms' tumor patients: preliminary results.
Medical and pediatric oncology 1996;27(5):404-7.
1996: Wendy Bruening; P Moffett; S Chia; G Heinrich; Jerry Pelletier
Identification of nuclear localization signals within the zinc fingers of the WT1 tumor suppressor gene product.
FEBS letters 1996;393(1):41-7.
1996: M Dehbi; Jerry Pelletier
PAX8-mediated activation of the wt1 tumor suppressor gene.
The EMBO journal 1996;15(16):4297-306.
1996: M Dehbi; Mohammad Hossein Ghahremani; M Lechner; Gregory R Dressler; Jerry Pelletier
The paired-box transcription factor, PAX2, positively modulates expression of the Wilms' tumor suppressor gene (WT1).
Oncogene 1996;13(3):447-53.
1996: P Moffett; M Dayo; M Reece; M K McCormick; Jerry Pelletier
Characterization of msim, a murine homologue of the Drosophila sim transcription factor.
Genomics 1996;35(1):144-55.
1996: Wendy Bruening; Jerry Pelletier
A non-AUG translational initiation event generates novel WT1 isoforms.
The Journal of biological chemistry 1996;271(15):8646-54.
1995: P Moffett; Wendy Bruening; H Nakagama; Nabeel Bardeesy; D Housman; David E Housman; Jerry Pelletier
Antagonism of WT1 activity by protein self-association.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(24):11105-9.
1995: Alessandra Gradi; R Tang-Wai; Heidi McBride; Lee Lee Chu; Gordon C Shore; Jerry Pelletier
The human steroidogenic acute regulatory (StAR) gene is expressed in the urogenital system and encodes a mitochondrial polypeptide.
Biochimica et biophysica acta 1995;1258(3):228-33.
1995: Paul Goodyer; M Dehbi; Elena Torban; W Bruening; Jerry Pelletier
Repression of the retinoic acid receptor-alpha gene by the Wilms' tumor suppressor gene product, wt1.
Oncogene 1995;10(6):1125-9.
1995: Nabeel Bardeesy; J B Beckwith; Jerry Pelletier
Clonal expansion and attenuated apoptosis in Wilms' tumors are associated with p53 gene mutations.
Cancer research 1995;55(2):215-9.
1995: Wendy Bruening; E Winnett; Jerry Pelletier
Wilms' tumor: a paradigm for insights into development and cancer.
Cancer investigation 1995;13(4):431-43.
1994: Nabeel Bardeesy; Bernhard Zabel; K Schmitt; Jerry Pelletier
WT1 mutations associated with incomplete Denys-Drash syndrome define a domain predicted to behave in a dominant-negative fashion.
Genomics 1994;21(3):663-4.
1994: Nabeel Bardeesy; D Falkoff; M J Petruzzi; Norma J Nowak; Bernhard Zabel; M Adam; M C Aguiar; Paul E Grundy; TB Shows; Jerry Pelletier
Anaplastic Wilms' tumour, a subtype displaying poor prognosis, harbours p53 gene mutations.
Nature genetics 1994;7(1):91-7.
1994: R Varanasi; Nabeel Bardeesy; Mohammad Hossein Ghahremani; M J Petruzzi; Norma J Nowak; M A Adam; Paul E Grundy; TB Shows; Jerry Pelletier
Fine structure analysis of the WT1 gene in sporadic Wilms tumors.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):3554-8.
1994: Jerry Pelletier
Molecular genetics of Wilms' tumor: insights into normal and abnormal renal development.
The Canadian journal of oncology 1994;4(2):262-72.
1993: K Vogan; M Bernstein; Jean-Marie Leclerc; L Brisson; Jean-Hugues Brossard; G M Brodeur; Jerry Pelletier; Philippe Gros
Absence of p53 gene mutations in primary neuroblastomas.
Cancer research 1993;53(21):5269-73.
1993: Wendy Bruening; Philippe Gros; T Sato; J Stanimir; Y Nakamura; D Housman; Jerry Pelletier
Analysis of the 11p13 Wilms' tumor suppressor gene (WT1) in ovarian tumors.
Cancer investigation 1993;11(4):393-9.
1992: Wendy Bruening; Nabeel Bardeesy; B L Silverman; R A Cohn; G A Machin; Andrew J Aronson; D Housman; Jerry Pelletier
Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development.
Nature genetics 1992;1(2):144-8.
1991: R Nicholson; Jerry Pelletier; S Y Le; Nahum Sonenberg
Structural and functional analysis of the ribosome landing pad of poliovirus type 2: in vivo translation studies.
Journal of virology 1991;65(11):5886-94.
1991: M Jaramillo; Jerry Pelletier; I Edery; P J Nielsen; Nahum Sonenberg
Multiple mRNAs encode the murine translation initiation factor eIF-4E.
The Journal of biological chemistry 1991;266(16):10446-51.
1989: F Rozen; Jerry Pelletier; Hans Trachsel; Nahum Sonenberg
A lysine substitution in the ATP-binding site of eucaryotic initiation factor 4A abrogates nucleotide-binding activity.
Molecular and cellular biology 1989;9(9):4061-3.
1989: M O Boylan; Jerry Pelletier; S Dhepagnon; S Trudel; N Sonenberg; Edward A Meighen
Construction of a fused LuxAB gene by site-directed mutagenesis.
Journal of bioluminescence and chemiluminescence 1989;4(1):310-6.
1989: Karen Meerovitch; Jerry Pelletier; Nahum Sonenberg
A cellular protein that binds to the 5'-noncoding region of poliovirus RNA: implications for internal translation initiation.
Genes & development 1989;3(7):1026-34.
1989: M Boylan; Jerry Pelletier; Edward A Meighen
Fused bacterial luciferase subunits catalyze light emission in eukaryotes and prokaryotes.
The Journal of biological chemistry 1989;264(4):1915-8.
1989: Jerry Pelletier; Nahum Sonenberg
Internal binding of eucaryotic ribosomes on poliovirus RNA: translation in HeLa cell extracts.
Journal of virology 1989;63(1):441-4.
1988: Jerry Pelletier; M E Flynn; G Kaplan; V Racaniello; Nahum Sonenberg
Mutational analysis of upstream AUG codons of poliovirus RNA.
Journal of virology 1988;62(12):4486-92.
1988: Jerry Pelletier; Nahum Sonenberg
Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA.
Nature 1988;334(6180):320-5.
1988: Jerry Pelletier; G Kaplan; Vincent Racaniello; Nahum Sonenberg
Translational efficiency of poliovirus mRNA: mapping inhibitory cis-acting elements within the 5' noncoding region.
Journal of virology 1988;62(7):2219-27.
1988: Jerry Pelletier; G Kaplan; Vincent Racaniello; Nahum Sonenberg
Cap-independent translation of poliovirus mRNA is conferred by sequence elements within the 5' noncoding region.
Molecular and cellular biology 1988;8(3):1103-12.
1987: Jerry Pelletier; Nahum Sonenberg
The involvement of mRNA secondary structure in protein synthesis.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1987;65(6):576-81.