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Daniela Pende

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Anatomy

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Yenan T Bryceson; Samuel C Chiang; Maurizio Arico; Karin Beutel; Nadine Binder; Ilka Bondzio; Kimberly C Gilmour; Jan-Inge Henter; Gritta Janka; Kai Lehmberg; Stefania Marcenaro; Andrea Maul-Pavicic; Raffaella Meazza; Lorenzo Moretta; Daniela Pende; Heike Ufheil; Thomas Vraetz; Denise Walshe; Udo zur Stadt; Stephan Ehl
A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes.
Elena Sieni; Luciano Attard; Alberto Bosi; Valentina Cetica; Filippo Gherlinzoni; Lorenzo Moretta; Daniela Pende; Andrea Piccin; Marco Rabusin; Ferdinando Carlo Sasso; Maurizio Aricò
Familial hemophagocytic lymphohistiocytosis may present during adulthood: clinical and genetic features of a small series.
Giuliana Magri; Aura Muntasell; Neus Romo; Andrea Sáez-Borderías; Daniela Pende; Daniel E Geraghty; Hartmut Hengel; Ana Angulo; Alessandro Moretta; Miguel López-Botet
NKp46 and DNAM-1 NK-cell receptors drive the response to human cytomegalovirus-infected myeloid dendritic cells overcoming viral immune evasion strategies.

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All Publications

2012: Yenan T Bryceson; Samuel C Chiang; Maurizio Arico; Karin Beutel; Nadine Binder; Ilka Bondzio; Kimberly C Gilmour; Jan-Inge Henter; Gritta Janka; Kai Lehmberg; Stefania Marcenaro; Andrea Maul-Pavicic; Raffaella Meazza; Lorenzo Moretta; Daniela Pende; Heike Ufheil; Thomas Vraetz; Denise Walshe; Udo zur Stadt; Stephan Ehl
A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes.
Blood 2012;119(12):2754-63.
2012: Elena Sieni; Luciano Attard; Alberto Bosi; Valentina Cetica; Filippo Gherlinzoni; Lorenzo Moretta; Daniela Pende; Andrea Piccin; Marco Rabusin; Ferdinando Carlo Sasso; Maurizio Aricò
Familial hemophagocytic lymphohistiocytosis may present during adulthood: clinical and genetic features of a small series.
PloS one 2012;7(9):e44649.
2011: Giuliana Magri; Aura Muntasell; Neus Romo; Andrea Sáez-Borderías; Daniela Pende; Daniel E Geraghty; Hartmut Hengel; Ana Angulo; Alessandro Moretta; Miguel López-Botet
NKp46 and DNAM-1 NK-cell receptors drive the response to human cytomegalovirus-infected myeloid dendritic cells overcoming viral immune evasion strategies.
Blood 2011;117(3):848-56.
2010: Valentina Cetica; Alessandra Santoro; Kimberly C Gilmour; Elena Sieni; Karin Beutel; Daniela Pende; Stefania Marcenaro; Florian Koch; Samantha Grieve; Rachel Wheeler; Fang Zhao; Udo zur Stadt; Gillian M Griffiths; Maurizio Aricò
STXBP2 mutations in children with familial haemophagocytic lymphohistiocytosis type 5.
Journal of medical genetics 2010;47(9):595-600.
2010: Aura Muntasell; Giuliana Magri; Daniela Pende; Ana Angulo; Miguel López-Botet
Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection.
Blood 2010;115(25):5170-9.
2009: Emanuela Marcenaro; Claudia Cantoni; Silvia Pesce; Carola Prato; Daniela Pende; Sophie Agaugué; Lorenzo Moretta; Alessandro Moretta
Uptake of CCR7 and acquisition of migratory properties by human KIR+ NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction.
Blood 2009;114(19):4108-16.
2009: Mirna Balsamo; Renato Zambello; Antonella Teramo; Marco Pedrazzi; Bianca Sparatore; Francesca Scordamaglia; Daniela Pende; Maria Cristina Mingari; Lorenzo Moretta; Alessandro Moretta; Gianpietro Semenzato; Massimo Vitale
Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NKp30.
Experimental hematology 2009;37(10):1167-75.
2009: Tadepally Lakshmikanth; Shannon Burke; Talib Hassan Ali; Silvia Kimpfler; Francesco Ursini; Loredana Ruggeri; Marusca Capanni; Viktor Umansky; Annette Paschen; Antje Sucker; Daniela Pende; Veronika Groh; Roberto Biassoni; Petter Höglund; Masashi Kato; Kazuko Shibuya; Dirk Schadendorf; Andrea Anichini; Soldano Ferrone; Andrea Velardi; Klas Kärre; Akira Shibuya; Ennio Carbone; Francesco Colucci
NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo.
The Journal of clinical investigation 2009;119(5):1251-63.
2009: Paolo Carrega; Gaetana Pezzino; Paola Queirolo; Irene Bonaccorsi; Michela Falco; Giuseppe Vita; Daniela Pende; Aldo Misefari; Alessandro Moretta; Maria Cristina Mingari; Lorenzo Moretta; Guido Ferlazzo
Susceptibility of human melanoma cells to autologous natural killer (NK) cell killing: HLA-related effector mechanisms and role of unlicensed NK cells.
PloS one 2009;4(12):e8132.
2008: Manuela Fogli; Domenico Mavilio; Enrico Brunetta; STEFANIA VARCHETTA; Khaled Ata; Gregg Roby; Colin Kovacs; dean follmann; Daniela Pende; Jeffrey Ward; Edward Barker; Emanuela Marcenaro; Alessandro Moretta; Anthony Fauci
Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals.
PLoS pathogens 2008;4(7):e1000101.
2008: Alessandra Santoro; Sonia Cannella; Antonino Trizzino; Giuseppa Bruno; Carmen De Fusco; Luigi D Notarangelo; Daniela Pende; Gillian M Griffiths; Maurizio Aricò
Mutations affecting mRNA splicing are the most common molecular defect in patients with familial hemophagocytic lymphohistiocytosis type 3.
Haematologica 2008;93(7):1086-90.
2008: Preben Boysen; Gjermund Gunnes; Daniela Pende; Mette Valheim; Anne K Storset
Natural killer cells in lymph nodes of healthy calves express CD16 and show both cytotoxic and cytokine-producing properties.
Developmental and comparative immunology 2008;32(7):773-83.
2008: Antonino Trizzino; Udo zur Stadt; I Ueda; K Risma; Gritta Janka; E Ishii; Karin Beutel; Janos Sumegi; Sonia Cannella; Daniela Pende; A Mian; Jan-Inge Henter; G Griffiths; Alessandra Santoro; Alexandra H Filipovich; Maurizio Aricò
Genotype-phenotype study of familial haemophagocytic lymphohistiocytosis due to perforin mutations.
Journal of medical genetics 2008;45(1):15-21.
2007: Cristina Maccalli; Daisuke Nonaka; Adriano Piris; Daniela Pende; Licia Rivoltini; Chiara Castelli; Giorgio Parmiani
NKG2D-mediated antitumor activity by tumor-infiltrating lymphocytes and antigen-specific T-cell clones isolated from melanoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(24):7459-68.
2007: Loredana Ruggeri; Antonella Mancusi; Marusca Capanni; Elena Urbani; Alessandra Carotti; Teresa Aloisi; Martin Stern; Daniela Pende; Katia Perruccio; Emanuela Burchielli; Fabiana Topini; Erika Bianchi; Franco Aversa; Massimo F Martelli; Andrea Velardi
Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value.
Blood 2007;110(1):433-40.
2007: Ilaria Lionello; Patrizia Mangia; Luca Gattinoni; Daniela Pende; Arcadi Cippone; Marialuisa Sensi; Patrizio Rigatti; Catia Traversari
CD8(+) T lymphocytes isolated from renal cancer patients recognize tumour cells through an HLA- and TCR/CD3-independent pathway.
Cancer immunology, immunotherapy : CII 2007;56(7):1065-76.
2007: Johanna Endt; Fiona E McCann; Catarina Almeida; Doris Urlaub; Rufina Leung; Daniela Pende; Daniel M Davis; Carsten Watzl
Inhibitory receptor signals suppress ligation-induced recruitment of NKG2D to GM1-rich membrane domains at the human NK cell immune synapse.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5606-11.
2007: Shlomo Nedvetzki; Stefanie Sowinski; Robert A Eagle; James Harris; Frédéric Vély; Daniela Pende; John Trowsdale; Eric Vivier; Siamon Gordon; Daniel M Davis
Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses.
Blood 2007;109(9):3776-85.
2006: Andrea Sáez-Borderías; Mónica Gumá; Ana Angulo; Beatriz Bellosillo; Daniela Pende; Miguel López-Botet
Expression and function of NKG2D in CD4+ T cells specific for human cytomegalovirus.
European journal of immunology 2006;36(12):3198-206.
2006: Lorenzo Moretta; Guido Ferlazzo; Cristina Bottino; Massimo Vitale; Daniela Pende; Maria Cristina Mingari; Alessandro Moretta
Effector and regulatory events during natural killer-dendritic cell interactions.
Immunological reviews 2006;214():219-28.
2006: Alessandra Santoro; Sonia Cannella; G Bossi; Federico Gallo; Antonino Trizzino; Daniela Pende; F Dieli; G Bruno; Jane C Stinchcombe; C Micalizzi; Carmela De Fusco; Cesare Danesino; Lorenzo Moretta; Luigi D Notarangelo; Gillian M Griffiths; Maurizio Aricò
Novel Munc13-4 mutations in children and young adult patients with haemophagocytic lymphohistiocytosis.
Journal of medical genetics 2006;43(12):953-60.
2006: Domenico Mavilio; Gabriella Lombardo; Audrey L Kinter; Manuela Fogli; Andrea la Sala; Saida Ortolano; Annahita Farschi; dean follmann; Roby Gregg; Colin Kovacs; Emanuela Marcenaro; Daniela Pende; Alessandro Moretta; Anthony Fauci
Characterization of the defective interaction between a subset of natural killer cells and dendritic cells in HIV-1 infection.
The Journal of experimental medicine 2006;203(10):2339-50.
2006: Stefania Marcenaro; Federico Gallo; Stefania Martini; Alessandra Santoro; Gillian M Griffiths; Maurizio Aricó; Lorenzo Moretta; Daniela Pende
Analysis of natural killer-cell function in familial hemophagocytic lymphohistiocytosis (FHL): defective CD107a surface expression heralds Munc13-4 defect and discriminates between genetic subtypes of the disease.
Blood 2006;108(7):2316-23.
2006: Lorenzo Moretta; Cristina Bottino; Daniela Pende; Roberta Castriconi; Maria Cristina Mingari; Alessandro Moretta
Surface NK receptors and their ligands on tumor cells.
Seminars in immunology 2006;18(3):151-8.
2006: Daniela Pende; Roberta Castriconi; Paola Romagnani; Grazia Maria Spaggiari; Stefania Marcenaro; Alessandra Dondero; Elena Lazzeri; Laura Lasagni; Stefania Martini; Paola Rivera; Andrea Capobianco; Lorenzo Moretta; Alessandro Moretta; Cristina Bottino
Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction.
Blood 2006;107(5):2030-6.
2005: Lorenzo Moretta; Cristina Bottino; Daniela Pende; Massimo Vitale; Maria Cristina Mingari; Alessandro Moretta
Human natural killer cells: Molecular mechanisms controlling NK cell activation and tumor cell lysis.
Immunology letters 2005;100(1):7-13.
2005: Christina Trambas; Federico Gallo; Daniela Pende; Stefania Marcenaro; Lorenzo Moretta; Carmela De Fusco; Alessandra Santoro; Luigi D Notarangelo; Maurizio Arico; Gillian M Griffiths
A single amino acid change, A91V, leads to conformational changes that can impair processing to the active form of perforin.
Blood 2005;106(3):932-7.
2005: Massimo Vitale; Mariella Della Chiesa; Simona Carlomagno; Daniela Pende; Maurizio Aricò; Lorenzo Moretta; Alessandro Moretta
NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor.
Blood 2005;106(2):566-71.
2005: Lorenzo Pilla; Paola Squarcina; Jorgelina Coppa; Vincenzo Mazzaferro; Veronica Huber; Daniela Pende; Cristina Maccalli; Gloria Sovena; Luigi Mariani; Chiara Castelli; Giorgio Parmiani; Licia Rivoltini
Natural killer and NK-Like T-cell activation in colorectal carcinoma patients treated with autologous tumor-derived heat shock protein 96.
Cancer research 2005;65(9):3942-9.
2005: Daniela Pende; Grazia Maria Spaggiari; Stefania Marcenaro; Stefania Martini; Paola Rivera; Andrea Capobianco; Michela Falco; Edoardo Lanino; Ivana Pierri; Renato Zambello; Andrea Bacigalupo; Maria Cristina Mingari; Alessandro Moretta; Lorenzo Moretta
Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112).
Blood 2005;105(5):2066-73.
2005: Daniela Pende; Cristina Bottino; Roberta Castriconi; Claudia Cantoni; Stefania Marcenaro; Paola Rivera; Grazia Maria Spaggiari; Alessandra Dondero; Barbara Carnemolla; Nicolas Reymond; Maria Cristina Mingari; Marc Lopez; Lorenzo Moretta; Alessandro Moretta
PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis.
Molecular immunology 2005;42(4):463-9.
2005: Ennio Carbone; Paola Neri; Maria Mesuraca; Mariateresa Fulciniti; Takemi Otsuki; Daniela Pende; Veronika Groh; Thomas Spies; Giuditta Pollio; David Cosman; Lucio Catalano; Pierfrancesco Tassone; Bruno Rotoli; Salvatore Venuta
HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells.
Blood 2005;105(1):251-8.
2004: Roberta Castriconi; Alessandra Dondero; Maria Valeria Corrias; Edoardo Lanino; Daniela Pende; Lorenzo Moretta; Cristina Bottino; Alessandro Moretta
Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction.
Cancer research 2004;64(24):9180-4.
2004: Lorenzo Moretta; Cristina Bottino; Daniela Pende; Massimo Vitale; Maria Cristina Mingari; Alessandro Moretta
Different checkpoints in human NK-cell activation.
Trends in immunology 2004;25(12):670-6.
2004: Massimo Vitale; Simona Carlomagno; Michela Falco; Daniela Pende; Elisa Romeo; Paola Rivera; Mariella Della Chiesa; Domenico Mavilio; Alessandro Moretta
Isolation of a novel KIR2DL3-specific mAb: comparative analysis of the surface distribution and function of KIR2DL2, KIR2DL3 and KIR2DS2.
International immunology 2004;16(10):1459-66.
2004: Lizzia Raffaghello; Ignazia Prigione; Irma Airoldi; Marta Camoriano; Isabella Levreri; Claudio Gambini; Daniela Pende; Alexander Steinle; Soldano Ferrone; Vito Pistoia
Downregulation and/or release of NKG2D ligands as immune evasion strategy of human neuroblastoma.
Neoplasia (New York, N.Y.) 2004;6(5):558-68.
2004: Cristina Bottino; Lorenzo Moretta; Daniela Pende; Massimo Vitale; Alessandro Moretta
Learning how to discriminate between friends and enemies, a lesson from Natural Killer cells.
Molecular immunology 2004;41(6-7):569-75.
2004: Francesco Lozupone; Daniela Pende; Vito Lelio Burgio; Chiara Castelli; Massimo Spada; Massimo Venditti; Francesca Luciani; Luana Lugini; Cristina Federici; Carlo Ramoni; Licia Rivoltini; Giorgio Parmiani; Filippo Belardelli; Paola Rivera; Stefania Marcenaro; Lorenzo Moretta; Stefano Fais
Effect of human natural killer and gammadelta T cells on the growth of human autologous melanoma xenografts in SCID mice.
Cancer research 2004;64(1):378-85.
2003: L Moretta; C Bottino; Guido Ferlazzo; Daniela Pende; Giovanni Melioli; Maria Cristina Mingari; A Moretta
Surface receptors and functional interactions of human natural killer cells: from bench to the clinic.
Cellular and molecular life sciences : CMLS 2003;60(10):2139-46.
2003: Cristina Bottino; Roberta Castriconi; Daniela Pende; Paola Rivera; Marina Nanni; Barbara Carnemolla; Claudia Cantoni; Jessica Grassi; Stefania Marcenaro; Nicolas Reymond; Massimo Vitale; Lorenzo Moretta; Marc Lopez; Alessandro Moretta
Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule.
The Journal of experimental medicine 2003;198(4):557-67.
2003: Lorenzo Moretta; Maria Cristina Mingari; Cristina Bottino; Daniela Pende; Roberto Biassoni; Alessandro Moretta
Cellular and molecular basis of natural killer and natural killer-like activity.
Immunology letters 2003;88(2):89-93.
2003: Cristina Maccalli; Daniela Pende; Chiara Castelli; Maria Cristina Mingari; Paul F Robbins; Giorgio Parmiani
NKG2D engagement of colorectal cancer-specific T cells strengthens TCR-mediated antigen stimulation and elicits TCR independent anti-tumor activity.
European journal of immunology 2003;33(7):2033-43.
2002: Lorenzo Moretta; Roberto Biassoni; Cristina Bottino; Claudia Cantoni; Daniela Pende; Maria Cristina Mingari; Alessandro Moretta
Human NK cells and their receptors.
Microbes and infection / Institut Pasteur 2002;4(15):1539-44.
2002: Daniela Pende; Paola Rivera; Stefania Marcenaro; Chien-Chung Chang; Roberto Biassoni; Romana Conte; Marek Kubin; David Cosman; Soldano Ferrone; Lorenzo Moretta; Alessandro Moretta
Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity.
Cancer research 2002;62(21):6178-86.
2002: Maurizio Aricò; Michaela Allen; Simona Brusa; Rita Clementi; Daniela Pende; Rita Maccario; Lorenzo Moretta; Cesare Danesino
Haemophagocytic lymphohistiocytosis: proposal of a diagnostic algorithm based on perforin expression.
British journal of haematology 2002;119(1):180-8.
2002: Régis T Costello; Simona Sivori; Emanuela Marcenaro; Marina Lafage-Pochitaloff; Marie-Joëlle Mozziconacci; Denis Reviron; Jean-Albert Gastaut; Daniela Pende; Daniel Olive; Alessandro Moretta
Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia.
Blood 2002;99(10):3661-7.
2002: Lorenzo Moretta; Cristina Bottino; Daniela Pende; Maria Cristina Mingari; Roberto Biassoni; Alessandro Moretta
Human natural killer cells: their origin, receptors and function.
European journal of immunology 2002;32(5):1205-11.
2001: Gabriella Pietra; Chiara Romagnani; Michela Falco; Massimo Vitale; Roberta Castriconi; Daniela Pende; Enrico Millo; S Anfossi; Roberto Biassoni; Lorenzo Moretta; Maria Cristina Mingari
The analysis of the natural killer-like activity of human cytolytic T lymphocytes revealed HLA-E as a novel target for TCR alpha/beta-mediated recognition.
European journal of immunology 2001;31(12):3687-93.
2001: Roberto Biassoni; Claudia Cantoni; Daniela Pende; Simona Sivori; Silvia Parolini; Massimo Vitale; Cristina Bottino; Alessandro Moretta
Human natural killer cell receptors and co-receptors.
Immunological reviews 2001;181():203-14.
2001: Grazia Maria Spaggiari; Roberta Carosio; Daniela Pende; Stefania Marcenaro; Paola Rivera; Maria Raffaella Zocchi; Lorenzo Moretta; Alessandro Poggi
NK cell-mediated lysis of autologous antigen-presenting cells is triggered by the engagement of the phosphatidylinositol 3-kinase upon ligation of the natural cytotoxicity receptors NKp30 and NKp46.
European journal of immunology 2001;31(6):1656-65.
2001: Paola Costa; S Rusconi; Domenico Mavilio; Manuela Fogli; Giuseppe Murdaca; Daniela Pende; Maria Cristina Mingari; M Galli; Lorenzo Moretta; Andrea De Maria
Differential disappearance of inhibitory natural killer cell receptors during HAART and possible impairment of HIV-1-specific CD8 cytotoxic T lymphocytes.
AIDS (London, England) 2001;15(8):965-74.
2001: Daniela Pende; Claudia Cantoni; Paola Rivera; Massimo Vitale; Roberta Castriconi; Stefania Marcenaro; Marina Nanni; Roberto Biassoni; Cristina Bottino; Alessandro Moretta; Lorenzo Moretta
Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin.
European journal of immunology 2001;31(4):1076-86.
2000: Roberto Biassoni; Claudia Cantoni; Michela Falco; Daniela Pende; Romano Millo; Lorenzo Moretta; Cristina Bottino; Alessandro Moretta
Human natural killer cell activating receptors.
Molecular immunology 2000;37(17):1015-24.
2000: Simona Sivori; Silvia Parolini; Emanuela Marcenaro; Roberta Castriconi; Daniela Pende; Romano Millo; Alessandro Moretta
Involvement of natural cytotoxicity receptors in human natural killer cell-mediated lysis of neuroblastoma and glioblastoma cell lines.
Journal of neuroimmunology 2000;107(2):220-5.
1999: Daniela Pende; Silvia Parolini; A Pessino; Simona Sivori; Raffaella Augugliaro; L Morelli; Emanuela Marcenaro; L Accame; A Malaspina; Roberto Biassoni; Cristina Bottino; Lorenzo Moretta; Alessandro Moretta
Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells.
The Journal of experimental medicine 1999;190(10):1505-16.
1999: Claudia Cantoni; Cristina Bottino; Raffaella Augugliaro; L Morelli; Emanuela Marcenaro; Roberta Castriconi; Massimo Vitale; Daniela Pende; Simona Sivori; Romano Millo; Roberto Biassoni; Lorenzo Moretta; Alessandro Moretta
Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells.
European journal of immunology 1999;29(10):3148-59.
1999: Simona Sivori; Daniela Pende; Cristina Bottino; Emanuela Marcenaro; A Pessino; Roberto Biassoni; Lorenzo Moretta; Alessandro Moretta
NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells.
European journal of immunology 1999;29(5):1656-66.
1999: Roberto Biassoni; A Pessino; Cristina Bottino; Daniela Pende; Lorenzo Moretta; Alessandro Moretta
The murine homologue of the human NKp46, a triggering receptor involved in the induction of natural cytotoxicity.
European journal of immunology 1999;29(3):1014-20.
1999: Massimo Vitale; Roberta Castriconi; Silvia Parolini; Daniela Pende; Mei-Ling Hsu; Lorenzo Moretta; David Cosman; Alessandro Moretta
The leukocyte Ig-like receptor (LIR)-1 for the cytomegalovirus UL18 protein displays a broad specificity for different HLA class I alleles: analysis of LIR-1 + NK cell clones.
International immunology 1999;11(1):29-35.
1998: Daniela Pende; L Accame; L Pareti; A Mazzocchi; Alessandro Moretta; G Parmiani; Lorenzo Moretta
The susceptibility to natural killer cell-mediated lysis of HLA class I-positive melanomas reflects the expression of insufficient amounts of different HLA class I alleles.
European journal of immunology 1998;28(8):2384-94.
1998: Claudia Cantoni; S Verdiani; Michela Falco; A Pessino; Michele Cilli; Romana Conte; Daniela Pende; M Ponte; M S Mikaelsson; Lorenzo Moretta; Roberto Biassoni
p49, a putative HLA class I-specific inhibitory NK receptor belonging to the immunoglobulin superfamily.
European journal of immunology 1998;28(6):1980-90.
1998: Claudia Cantoni; Roberto Biassoni; Daniela Pende; Simona Sivori; L Accame; L Pareti; G Semenzato; Lorenzo Moretta; Alessandro Moretta; Cristina Bottino
The activating form of CD94 receptor complex: CD94 covalently associates with the Kp39 protein that represents the product of the NKG2-C gene.
European journal of immunology 1998;28(1):327-38.
1997: Daniela Pende; Simona Sivori; L Accame; L Pareti; Michela Falco; D Geraghty; P Le Bouteiller; Lorenzo Moretta; Alessandro Moretta
HLA-G recognition by human natural killer cells. Involvement of CD94 both as inhibitory and as activating receptor complex.
European journal of immunology 1997;27(8):1875-80.
1996: L Moretta; M C Mingari; Daniela Pende; Cristina Bottino; Roberto Biassoni; A Moretta
The molecular basis of natural killer (NK) cell recognition and function.
Journal of clinical immunology 1996;16(5):243-53.
1996: Cristina Bottino; Simona Sivori; M Vitale; Claudia Cantoni; Michela Falco; Daniela Pende; L Morelli; Raffaella Augugliaro; G Semenzato; Roberto Biassoni; Lorenzo Moretta; Alessandro Moretta
A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation.
European journal of immunology 1996;26(8):1816-24.
1996: Daniela Pende; Roberto Biassoni; Claudia Cantoni; S Verdiani; Michela Falco; C di Donato; L Accame; Cristina Bottino; Alessandro Moretta; Lorenzo Moretta
The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.
The Journal of experimental medicine 1996;184(2):505-18.
1996: M Vitale; Simona Sivori; Daniela Pende; Raffaella Augugliaro; C Di Donato; A Amoroso; M Malnati; Cristina Bottino; Lorenzo Moretta; Alessandro Moretta
Physical and functional independency of p70 and p58 natural killer (NK) cell receptors for HLA class I: their role in the definition of different groups of alloreactive NK cell clones.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(4):1453-7.
1996: A Moretta; M Vitale; Simona Sivori; L Morelli; Daniela Pende; Cristina Bottino
Inhibitory and activatory receptors for HLA class I molecules in human natural killer cells.
Chemical immunology 1996;64():77-87.
1995: Alessandro Moretta; Simona Sivori; M Vitale; Daniela Pende; L Morelli; Raffaella Augugliaro; Cristina Bottino; Lorenzo Moretta
Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.
The Journal of experimental medicine 1995;182(3):875-84.
1995: Roberto Biassoni; Michela Falco; A Cambiaggi; P Costa; S Verdiani; Daniela Pende; R Conte; C Di Donato; P Parham; Lorenzo Moretta
Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones.
The Journal of experimental medicine 1995;182(2):605-9.
1995: M Vitale; Simona Sivori; Daniela Pende; Lorenzo Moretta; Alessandro Moretta
Coexpression of two functionally independent p58 inhibitory receptors in human natural killer cell clones results in the inability to kill all normal allogeneic target cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3536-40.
1995: Ermanno Ciccone; Daniela Pende; L Nanni; C Di Donato; O Viale; A Beretta; M Vitale; Simona Sivori; Alessandro Moretta; Lorenzo Moretta
General role of HLA class I molecules in the protection of target cells from lysis by natural killer cells: evidence that the free heavy chains of class I molecules are not sufficient to mediate the protective effect.
International immunology 1995;7(3):393-400.
1994: Alessandro Moretta; M Vitale; Simona Sivori; Cristina Bottino; L Morelli; Raffaella Augugliaro; M Barbaresi; Daniela Pende; Ermanno Ciccone; M Lopez-Botet; Lorenzo Moretta
Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.
The Journal of experimental medicine 1994;180(2):545-55.
1994: Ermanno Ciccone; Daniela Pende; M Vitale; L Nanni; C Di Donato; Cristina Bottino; L Morelli; O Viale; A Amoroso; Alessandro Moretta
Self class I molecules protect normal cells from lysis mediated by autologous natural killer cells.
European journal of immunology 1994;24(4):1003-6.
1993: Frank T Christiansen; Campbell S Witt; Ermanno Ciccone; DC Townend; Daniela Pende; D Viale; L J Abraham; Roger L Dawkins; L Moretta
Human natural killer (NK) alloreactivity and its association with the major histocompatibility complex: ancestral haplotypes encode particular NK-defined haplotypes.
The Journal of experimental medicine 1993;178(3):1033-9.
1993: Frank T Christiansen; Campbell S Witt; Ermanno Ciccone; Daniela Pende; O Viale; Roger L Dawkins; L Moretta
Natural killer defined haplotypes are associated with particular ancestral haplotypes: implications for bone marrow transplantation.
Transplantation proceedings 1993;25(1 Pt 2):1259-60.
1992: Frank T Christiansen; Campbell S Witt; Ermanno Ciccone; Daniela Pende; O Viale; Roger L Dawkins; L Moretta
Ancestral haplotypes predict EC-1 alleles.
Transplantation proceedings 1992;24(5):2333-4.
1992: Ermanno Ciccone; Daniela Pende; O Viale; A Than; C Di Donato; Anna Maria Orengo; Roberto Biassoni; S Verdiani; A Amoroso; Alessandro Moretta
Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2).
The Journal of experimental medicine 1992;176(4):963-71.
1992: Marco COLONna; Thomas Spies; Jack L Strominger; Ermanno Ciccone; A Moretta; L Moretta; Daniela Pende; O Viale
Alloantigen recognition by two human natural killer cell clones is associated with HLA-C or a closely linked gene.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):7983-5.
1992: Lorenzo Moretta; Ermanno Ciccone; Daniela Pende; O Viale; C Di Donato; G Tripodi; Anna Maria Orengo; J Guardiola; Alessandro Moretta
Existence of a natural killer (NK) cell repertoire for (allo)antigen recognition: definition of five distinct NK-determined allospecificities in humans.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():98-9.
1992: Ermanno Ciccone; Daniela Pende; O Viale; C Di Donato; G Tripodi; Anna Maria Orengo; J Guardiola; Alessandro Moretta; Lorenzo Moretta
Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans.
The Journal of experimental medicine 1992;175(3):709-18.
1992: Lorenzo Moretta; Ermanno Ciccone; Daniela Pende; G Tripodi; Cristina Bottino; Alessandro Moretta
Human natural killer cells: clonally distributed specific functions and triggering surface molecules.
Laboratory investigation; a journal of technical methods and pathology 1992;66(2):138-42.
1992: Alessandro Moretta; Cristina Bottino; G Tripodi; M Vitale; Daniela Pende; L Morelli; Raffaella Augugliaro; M Barbaresi; Ermanno Ciccone; Romano Millo
Novel surface molecules involved in human NK cell activation and triggering of the lytic machinery.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1992;7():6-10.
1991: Alessandro Moretta; Alessandro Poggi; Daniela Pende; G Tripodi; Anna Maria Orengo; N Pella; Raffaella Augugliaro; Cristina Bottino; Ermanno Ciccone; Lorenzo Moretta
CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta.
The Journal of experimental medicine 1991;174(6):1393-8.
1991: G Tripodi; Anna Maria Orengo; Daniela Pende; M Barbaresi; Cristina Bottino; Ermanno Ciccone; Romano Millo; A Moretta
Subpopulations of human NK (CD3-CD16+) lymphocytes identified by monoclonal antibodies directed to clonally distributed functional surface molecules.
Cytotechnology 1991;5(Suppl 1):141-4.
1991: Ermanno Ciccone; O Viale; Daniela Pende; M Malnati; Alessandro Moretta; Lorenzo Moretta
Specificity of human T lymphocytes expressing a gamma/delta T cell antigen receptor. Recognition of a polymorphic determinant of HLA class I molecules by a gamma/delta+ clone.
Current topics in microbiology and immunology 1991;173():223-7.
1990: Alessandro Moretta; Cristina Bottino; Daniela Pende; G Tripodi; G Tambussi; O Viale; Anna Maria Orengo; M Barbaresi; A Merli; Ermanno Ciccone
Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition.
The Journal of experimental medicine 1990;172(6):1589-98.
1990: Ermanno Ciccone; Marco COLONna; O Viale; Daniela Pende; C Di Donato; D Reinharz; A Amoroso; M Jeannet; J Guardiola; Alessandro Moretta
Susceptibility or resistance to lysis by alloreactive natural killer cells is governed by a gene in the human major histocompatibility complex between BF and HLA-B.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9794-7.
1990: Alessandro Moretta; Cristina Bottino; Daniela Pende; G Tripodi; Anna Maria Orengo; Romano Millo; P G Pelicci; Ermanno Ciccone; Lorenzo Moretta
Human T lymphocytes expressing TCR gamma/delta.
Research in immunology 1990;141(7):630-5.
1990: Andrea De Maria; M S Malnati; A Poggi; Daniela Pende; F Cottafava; Lorenzo Moretta
Clonal analysis of joint fluid T lymphocytes in patients with juvenile rheumatoid arthritis.
The Journal of rheumatology 1990;17(8):1073-8.
1990: Ermanno Ciccone; Daniela Pende; O Viale; G Tambussi; Silvano Ferrini; Roberto Biassoni; A Longo; J Guardiola; Alessandro Moretta; Lorenzo Moretta
Specific recognition of human CD3-CD16+ natural killer cells requires the expression of an autosomic recessive gene on target cells.
The Journal of experimental medicine 1990;172(1):47-52.
1989: Alessandro Moretta; G Tambussi; Ermanno Ciccone; Daniela Pende; G Melioli; Lorenzo Moretta
CD16 surface molecules regulate the cytolytic function of CD3CD16+ human natural killer cells.
International journal of cancer. Journal international du cancer 1989;44(4):727-30.
1989: Ermanno Ciccone; O Viale; Daniela Pende; M Malnati; G Battista Ferrara; S Barocci; Alessandro Moretta; Lorenzo Moretta
Specificity of human T lymphocytes expressing a gamma/delta T cell antigen receptor. Recognition of a polymorphic determinant of HLA class I molecules by a gamma/delta clone.
European journal of immunology 1989;19(7):1267-71.
1989: Giovanni Melioli; Ermanno Ciccone; Maria Cristina Mingari; Daniela Pende; O Viale; G Tambussi; A Merli; Alessandro Moretta; Lorenzo Moretta
Specific recognition by CD3- NK cells: a limiting dilution analysis of the frequency of alloreactive CD3- lymphocyte precursors.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():56-7.
1989: Alessandro Moretta; Ermanno Ciccone; G Tambussi; Cristina Bottino; O Viale; Daniela Pende; A Santoni; Maria Cristina Mingari
Surface molecules involved in CD3-negative NK cell function. A novel molecule which regulates the activation of a subset of human NK cells.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():48-52.
1988: Ermanno Ciccone; O Viale; Daniela Pende; M Malnati; Roberto Biassoni; Giovanni Melioli; Alessandro Moretta; Eric O Long; Lorenzo Moretta
Specific lysis of allogeneic cells after activation of CD3- lymphocytes in mixed lymphocyte culture.
The Journal of experimental medicine 1988;168(6):2403-8.
1988: Ermanno Ciccone; O Viale; Cristina Bottino; Daniela Pende; Nicola Migone; Giulia Casorati; G Tambussi; Alessandro Moretta; Lorenzo Moretta
Antigen recognition by human T cell receptor gamma-positive lymphocytes. Specific lysis of allogeneic cells after activation in mixed lymphocyte culture.
The Journal of experimental medicine 1988;167(4):1517-22.
1987: Andrea De Maria; M Malnati; Alessandro Moretta; Daniela Pende; Cristina Bottino; Giulia Casorati; F Cottafava; Giovanni Melioli; Maria Cristina Mingari; Nicola Migone
CD3+4-8-WT31-(T cell receptor gamma+) cells and other unusual phenotypes are frequently detected among spontaneously interleukin 2-responsive T lymphocytes present in the joint fluid in juvenile rheumatoid arthritis. A clonal analysis.
European journal of immunology 1987;17(12):1815-9.
1987: Maria Cristina Mingari; Silvano Ferrini; Daniela Pende; Cristina Bottino; I Prigione; Alessandro Moretta; Lorenzo Moretta
Phenotypic and functional analysis of human CD3+ and CD3- clones with "lymphokine-activated killer" (LAK) activity. Frequent occurrence of CD3+ LAK clones which produce interleukin-2.
International journal of cancer. Journal international du cancer 1987;40(4):495-8.
1987: Lorenzo Moretta; Daniela Pende; Cristina Bottino; Nicola Migone; Ermanno Ciccone; Silvano Ferrini; Maria Cristina Mingari; Alessandro Moretta
Human CD3+4-8-WT31- T lymphocyte populations expressing the putative T cell receptor gamma-gene product. A limiting dilution and clonal analysis.
European journal of immunology 1987;17(9):1229-34.
1987: Cristina Bottino; Silvano Ferrini; Ermanno Ciccone; I Prigione; Daniela Pende; Maria Cristina Mingari; Lorenzo Moretta; Alessandro Moretta
Analysis of CD3-associated molecules in CD4- 8- human T cell clones lacking the typical alpha/beta T cell receptor.
La Ricerca in clinica e in laboratorio 1987;17(2):125-9.
1986: Lorenzo Moretta; Daniela Pende; R Cozzani; A Merli; M Bagnasco; Maria Cristina Mingari
T cell nature of some lymphokine-activated killer (LAK) cells. Frequency analysis of LAK precursors within human T cell populations and clonal analysis of LAK effector cells.
European journal of immunology 1986;16(12):1623-5.
1986: Maria Cristina Mingari; Daniela Pende; R Cozzani; A Merli; A Poggi; S Ferrini; Lorenzo Moretta
Both the precursors and the effectors of human lymphokine-activated killer (LAK) cells may belong to T lymphocytes.
La Ricerca in clinica e in laboratorio 1986;16(3):437-41.
1986: Maria Cristina Mingari; F Gerosa; E Maggi; R Cozzani; Daniela Pende; C Bottino; A Poggi; S Romagnani; Lorenzo Moretta
Heterogeneity of B cell growth factor (BCGF)-producing T cells in humans. Clonal analysis of BCGF-producing cells within T4+ and T8+ subsets and evidence for the involvement of different growth factors in different BCGF assays.
La Ricerca in clinica e in laboratorio 1986;16(1):23-8.