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Sylvia Pender

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Up-Regulation

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Co-Publications
Name
28
MacDonald, Thomas
11
Monteleone, Giovanni
5
Saarialho-Kere, Ulpu
5
Bajaj-Elliott, M
5
Wathen, NC
4
Salmela, Mikko
4
Di Sabatino, Antonio
3
Gordon, John
3
McKenzie, C
3
Pickard, Karen
2
Poulsom, R
2
Sanderson, Ian
2
Picariello, Lucia
2
Chance, Victoria
2
Fairclough, Peter

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Publications

TOP 3
Di Sabatino Antonio; Saarialho-Kere Ulpu; Buckley Mark G; Gordon John N; Biancheri Paolo; Rovedatti Laura; Corazza Gino R; Macdonald Thomas T; Pender Sylvia L F
Stromelysin-1 and macrophage metalloelastase expression in the intestinal mucosa of Crohn's disease patients treated with infliximab.
Di Sabatino A; Jackson C L; Pickard K M; Buckley M; Rovedatti L; Leakey N A B; Picariello L; Cazzola P; Monteleone G; Tonelli F; Corazza G R; MacDonald T T; Pender S L
Transforming growth factor beta signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures.
Gordon John N; Pickard Karen M; Di Sabatino Antonio; Prothero Joanna D; Pender Sylvia L F; Goggin Patrick M; MacDonald Thomas T
Matrix metalloproteinase-3 production by gut IgG plasma cells in chronic inflammatory bowel disease.

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All Publications

2009: Di Sabatino Antonio; Saarialho-Kere Ulpu; Buckley Mark G; Gordon John N; Biancheri Paolo; Rovedatti Laura; Corazza Gino R; Macdonald Thomas T; Pender Sylvia L F
Stromelysin-1 and macrophage metalloelastase expression in the intestinal mucosa of Crohn's disease patients treated with infliximab.
European journal of gastroenterology & hepatology 2009;21(9):1049-55.
2009: Di Sabatino A; Jackson C L; Pickard K M; Buckley M; Rovedatti L; Leakey N A B; Picariello L; Cazzola P; Monteleone G; Tonelli F; Corazza G R; MacDonald T T; Pender S L
Transforming growth factor beta signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures.
Gut 2009;58(6):777-89.
2008: Gordon John N; Pickard Karen M; Di Sabatino Antonio; Prothero Joanna D; Pender Sylvia L F; Goggin Patrick M; MacDonald Thomas T
Matrix metalloproteinase-3 production by gut IgG plasma cells in chronic inflammatory bowel disease.
Inflammatory bowel diseases 2008;14(2):195-203.
2007: Di Sabatino Antonio; Pender Sylvia L F; Jackson Claire L; Prothero Joanna D; Gordon John N; Picariello Lucia; Rovedatti Laura; Docena Guillermo; Monteleone Giovanni; Rampton David S; Tonelli Francesco; Corazza Gino R; MacDonald Thomas T
Functional modulation of Crohn's disease myofibroblasts by anti-tumor necrosis factor antibodies.
Gastroenterology 2007;133(1):137-49.
2006: Pender Sylvia L F; Li C K F; Di Sabatino A; MacDonald T T; Buckley M G
Role of macrophage metalloelastase in gut inflammation.
Annals of the New York Academy of Sciences 2006;1072():386-8.
2006: Kruidenier Laurens; MacDonald Thomas T; Collins Jane E; Pender Sylvia L F; Sanderson Ian R
Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells.
Gastroenterology 2006;130(1):127-36.
2005: Pender S L-F; Chance V; Whiting C V; Buckley M; Edwards M; Pettipher R; MacDonald T T
Systemic administration of the chemokine macrophage inflammatory protein 1alpha exacerbates inflammatory bowel disease in a mouse model.
Gut 2005;54(8):1114-20.
2004: Pender Sylvia L F; MacDonald Thomas T
Matrix metalloproteinases and the gut - new roles for old enzymes.
Current opinion in pharmacology 2004;4(6):546-50.
2004: Salmela M T; Pender S L F; Karjalainen-Lindsberg M-L; Puolakkainen P; Macdonald T T; Saarialho-Kere U
Collagenase-1 (MMP-1), matrilysin-1 (MMP-7), and stromelysin-2 (MMP-10) are expressed by migrating enterocytes during intestinal wound healing.
Scandinavian journal of gastroenterology 2004;39(11):1095-104.
2004: Li Chris K F; Pender Sylvia L F; Pickard Karen M; Chance Victoria; Holloway Judith A; Huett Alan; Gonçalves Nathalie S; Mudgett John S; Dougan Gordon; Frankel Gad; MacDonald Thomas T
Impaired immunity to intestinal bacterial infection in stromelysin-1 (matrix metalloproteinase-3)-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):5171-9.
2004: Pender S L F; Croucher P J P; Mascheretti S; Prothero J D; Fisher S A; MacDonald T T; Schreiber S; Ye Shu
Transmission disequilibrium test of stromelysin-1 gene variation in relation to Crohn's disease.
Journal of medical genetics 2004;41(9):e112.
2004: Mimura Toshiki; Bateman Adrian C; Lee Ronald L; Johnson Penelope A; McDonald Peter J; Talbot Ian C; Kamm Michael A; MacDonald Thomas T; Pender Sylvia L F
Up-regulation of collagen and tissue inhibitors of matrix metalloproteinase in colonic diverticular disease.
Diseases of the colon and rectum 2004;47(3):371-8; discussion 378-9.
2003: Pender Sylvia Lin Foon; Braegger Christian; Gunther Ute; Monteleone Giovanni; Meuli Martin; Schuppan Detlef; Macdonald Thomas Thornton
Matrix metalloproteinases in necrotising enterocolitis.
Pediatric research 2003;54(2):160-4.
2003: Monteleone Giovanni; Holloway Judith; Salvati Virginia M; Pender Sylvia L-F; Fairclough Peter D; Croft Nicholas; MacDonald Thomas T
Activated STAT4 and a functional role for IL-12 in human Peyer's patches.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(1):300-7.
2002: Salmela M T; MacDonald T T; Black D; Irvine B; Zhuma T; Saarialho-Kere U; Pender S L F
Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: analysis by gene array and in situ hybridisation.
Gut 2002;51(4):540-7.
2002: Shek Fanny Wai-Tsing; Benyon Robert Christopher; Walker Fiona Mairi; McCrudden Peter Raymond; Pender Sylvia Lin Foon; Williams Elizabeth Jean; Johnson Penelope Ann; Johnson Colin David; Bateman Adrian Calvin; Fine David Roger; Iredale John Peter
Expression of transforming growth factor-beta 1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitis.
The American journal of pathology 2002;160(5):1787-98.
2001: Shaida A; Kenyon G; Devalia J; Davies R J; MacDonald T T; Pender S L
Matrix metalloproteinases and their inhibitors in the nasal mucosa of patients with perennial allergic rhinitis.
The Journal of allergy and clinical immunology 2001;108(5):791-6.
2001: Jones C A; Vance G H; Power L L; Pender S L; Macdonald T T; Warner J O
Costimulatory molecules in the developing human gastrointestinal tract: a pathway for fetal allergen priming.
The Journal of allergy and clinical immunology 2001;108(2):235-41.
2001: Monteleone G; Pender S L; Wathen N C; MacDonald T T
Interferon-alpha drives T cell-mediated immunopathology in the intestine.
European journal of immunology 2001;31(8):2247-55.
2001: Salmela M T; Pender S L; Reunala T; MacDonald T; Saarialho-Kere U
Parallel expression of macrophage metalloelastase (MMP-12) in duodenal and skin lesions of patients with dermatitis herpetiformis.
Gut 2001;48(4):496-502.
2001: Monteleone G; Pender S L; Alstead E; Hauer A C; Lionetti P; McKenzie C; MacDonald T T
Role of interferon alpha in promoting T helper cell type 1 responses in the small intestine in coeliac disease.
Gut 2001;48(3):425-9.
2000: Pender S L; Salmela M T; Monteleone G; Schnapp D; McKenzie C; Spencer J; Fong S; Saarialho-Kere U; MacDonald T T
Ligation of alpha4ss1 integrin on human intestinal mucosal mesenchymal cells selectively Up-regulates membrane type-1 matrix metalloproteinase and confers a migratory phenotype.
The American journal of pathology 2000;157(6):1955-62.
2000: Pender S L; Quinn J J; Sanderson I R; MacDonald T T
Butyrate upregulates stromelysin-1 production by intestinal mesenchymal cells.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(5):G918-24.
2000: Nagata S; McKenzie C; Pender S L; Bajaj-Elliott M; Fairclough P D; Walker-Smith J A; Monteleone G; MacDonald T T
Human Peyer's patch T cells are sensitized to dietary antigen and display a Th cell type 1 cytokine profile.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):5315-21.
2000: Heuschkel R B; MacDonald T T; Monteleone G; Bajaj-Elliott M; Smith J A; Pender S L
Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease.
Gut 2000;47(1):57-62.
2000: MacDonald T T; Monteleone G; Pender S L
Recent developments in the immunology of inflammatory bowel disease.
Scandinavian journal of immunology 2000;51(1):2-9.
1999: Monteleone G; MacDonald T T; Wathen N C; Pallone F; Pender S L
Enhancing Lamina propria Th1 cell responses with interleukin 12 produces severe tissue injury.
Gastroenterology 1999;117(5):1069-77.
1999: MacDonald T T; Bajaj-Elliott M; Pender S L
T cells orchestrate intestinal mucosal shape and integrity.
Immunology today 1999;20(11):505-10.
1999: Pender S L; McKenzie C; Shaida A; MacDonald T T
Regulation of matrix metalloproteinases in human intestinal mucosa.
Annals of the New York Academy of Sciences 1999;878():581-2.
1998: Pender S L; MacDonald T T
Regulation of matrix metalloproteinase production in human fetal intestinal mesenchymal cells by cytokines and the bacterial superantigen Staphylococcus aureus enterotoxin B.
Annals of the New York Academy of Sciences 1998;859():188-91.
1998: Bajaj-Elliott M; Pender S L; Poulsom R; Macdonald T T
Upregulation of keratinocyte growth factor during T-cell immunity in the gut mucosa.
Annals of the New York Academy of Sciences 1998;859():184-7.
1998: Bajaj-Elliott M; Poulsom R; Pender S L; Wathen N C; MacDonald T T
Interactions between stromal cell--derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia.
The Journal of clinical investigation 1998;102(8):1473-80.
1998: Pender S L; Breese E J; Günther U; Howie D; Wathen N C; Schuppan D; MacDonald T T
Suppression of T cell-mediated injury in human gut by interleukin 10: role of matrix metalloproteinases.
Gastroenterology 1998;115(3):573-83.
1998: MacDonald T T; Pender S L
Proteolytic enzymes in inflammatory bowel disease.
Inflammatory bowel diseases 1998;4(2):157-64.
1998: Pender S L; Fell J M; Chamow S M; Ashkenazi A; MacDonald T T
A p55 TNF receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(8):4098-103.
1997: Pender S L; Tickle S P; Docherty A J; Howie D; Wathen N C; MacDonald T T
A major role for matrix metalloproteinases in T cell injury in the gut.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(4):1582-90.

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