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Charles Pendley

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Brian J Geist; Kenneth Goldberg; Chao Han; Thomas McIntosh; Charles Pendley; Tong-Yuan Yang; Darryl Davis; Hugh M Davis
A novel approach for the simultaneous quantification of a therapeutic monoclonal antibody in serum produced from two distinct host cell lines.
Jacqueline M Benson; Carrie M Brodmerkel; Charles Pendley; Clifford W Sachs; Gopi Shankar; George Treacy; Honghui Zhou; Mary Ann Mascelli
Therapeutic targeting of the IL-12/23 pathways: generation and characterization of ustekinumab.
Charles Pendley; Gopi Shankar
Bioanalytical interferences in immunoassays for antibody biotherapeutics.

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All Publications

2013: Brian J Geist; Kenneth Goldberg; Chao Han; Thomas McIntosh; Charles Pendley; Tong-Yuan Yang; Darryl Davis; Hugh M Davis
A novel approach for the simultaneous quantification of a therapeutic monoclonal antibody in serum produced from two distinct host cell lines.
mAbs 2013;5(1):150-61.
2011: Jacqueline M Benson; Carrie M Brodmerkel; Charles Pendley; Clifford W Sachs; Gopi Shankar; George Treacy; Honghui Zhou; Mary Ann Mascelli
Therapeutic targeting of the IL-12/23 pathways: generation and characterization of ustekinumab.
Nature biotechnology 2011;29(7):615-24.
2011: Charles Pendley; Gopi Shankar
Bioanalytical interferences in immunoassays for antibody biotherapeutics.
Bioanalysis 2011;3(7):703-6.
2010: Cathy K Gelotte; Mary Jane Prior; Charles Pendley; Brenda Zimmerman; Bernard J Lavins
Multiple-dose pharmacokinetics and safety of an ibuprofen-pseudoephedrine cold suspension in children.
Clinical pediatrics 2010;49(7):678-85.
2010: Manjula Reddy; Gisela Torres; Thomas McCormick; Colleen Marano; Kevin Cooper; Newman Yeilding; Yuhua Wang; Charles Pendley; Uma Prabhakar; Jackson Wong; Cuc Davis; Stephen Xu; Carrie Brodmerkel
Positive treatment effects of ustekinumab in psoriasis: analysis of lesional and systemic parameters.
The Journal of dermatology 2010;37(5):413-25.
2009: Zhenhua Xu; Thuy Vu; Howard Lee; Chuanpu Hu; Jie Ling; Hong Yan; Daniel Baker; Anna Beutler; Charles Pendley; Carrie Wagner; Hugh M Davis; Honghui Zhou
Population pharmacokinetics of golimumab, an anti-tumor necrosis factor-alpha human monoclonal antibody, in patients with psoriatic arthritis.
Journal of clinical pharmacology 2009;49(9):1056-70.
2007: Sudha Visvanathan; Joseph C Marini; Josef S Smolen; E William St Clair; Charles Pritchard; William Shergy; Charles Pendley; Daniel Baker; Mohan Bala; Timothy Gathany; John Han; Carrie Wagner
Changes in biomarkers of inflammation and bone turnover and associations with clinical efficacy following infliximab plus methotrexate therapy in patients with early rheumatoid arthritis.
The Journal of rheumatology 2007;34(7):1465-74.
2007: Manjula Reddy; Cuc Davis; Jackson Wong; Paul Marsters; Charles Pendley; Uma Prabhakar
Modulation of CLA, IL-12R, CD40L, and IL-2Ralpha expression and inhibition of IL-12- and IL-23-induced cytokine secretion by CNTO 1275.
Cellular immunology 2007;247(1):1-11.
2007: Alice B Gottlieb; Kevin D Cooper; Thomas S McCormick; Eiko Toichi; Daniel E Everitt; Bart Frederick; Yaowei Zhu; Charles Pendley; Martin A Graham; Mary Ann Mascelli
A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis.
Current medical research and opinion 2007;23(5):1081-92.
2007: Gopi Shankar; Charles Pendley; Kathryn E Stein
A risk-based bioanalytical strategy for the assessment of antibody immune responses against biological drugs.
Nature biotechnology 2007;25(5):555-61.
2007: Honghui Zhou; Haishan Jang; Roy M Fleischmann; Esther Bouman-Thio; Zhenhua Xu; Joseph C Marini; Charles Pendley; Qun Jiao; Gopi Shankar; Stanley J Marciniak; Stanley B Cohen; Mahboob U Rahman; Daniel Baker; Mary Ann Mascelli; Hugh M Davis; Daniel E Everitt
Pharmacokinetics and safety of golimumab, a fully human anti-TNF-alpha monoclonal antibody, in subjects with rheumatoid arthritis.
Journal of clinical pharmacology 2007;47(3):383-96.
2006: Eiko Toichi; Gisela Torres; Thomas S McCormick; Timothy Chang; Mary Ann Mascelli; Catharine Lisa Kauffman; Nancy Aria; Alice B Gottlieb; Daniel E Everitt; Bart Frederick; Charles Pendley; Kevin D Cooper
An anti-IL-12p40 antibody down-regulates type 1 cytokines, chemokines, and IL-12/IL-23 in psoriasis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4917-26.
2005: D Horninger; Edward Eirikis; Charles Pendley; J Giles-Komar; Hugh M Davis; B E Miller
A one-step, competitive electrochemiluminescence-based immunoassay method for the quantification of a fully human anti-TNFalpha antibody in human serum.
Journal of pharmaceutical and biomedical analysis 2005;38(4):703-8.
2004: Catharine Lisa Kauffman; Nancy Aria; Eiko Toichi; Thomas S McCormick; Kevin D Cooper; Alice B Gottlieb; Daniel E Everitt; Bart Frederick; Yaowei Zhu; Martin A Graham; Charles Pendley; Mary Ann Mascelli
A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis.
The Journal of investigative dermatology 2004;123(6):1037-44.
2004: Uma Prabhakar; Edward Eirikis; Manjula Reddy; Eva Silvestro; Susan Spitz; Charles Pendley; Hugh M Davis; Bruce E Miller
Validation and comparative analysis of a multiplexed assay for the simultaneous quantitative measurement of Th1/Th2 cytokines in human serum and human peripheral blood mononuclear cell culture supernatants.
Journal of immunological methods 2004;291(1-2):27-38.