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Xiao-ding Peng

Research Profile

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Chemicals & Drugs

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Prostatic Intraepithelial Neoplasia

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Veronique Nogueira; Xiao-ding Peng; Neha Sarvepalli; Nahum Sonenberg; Deepa Sundararajan; Jennifer M Kwan; Nissim Hay
Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis.
Pei-Zhang Xu; Mei-Ling Chen; S-M Jeon; Xiao-ding Peng; Nissim Hay
The effect Akt2 deletion on tumor development in Pten(+/-) mice.
Raul M Luque; Beatriz S Soares; Xiao-ding Peng; Sonia Krishnan; Jose Cordoba; Lawrence A Frohman; Rhonda D Kineman
Use of the metallothionein promoter-human growth hormone-releasing hormone (GHRH) mouse to identify regulatory pathways that suppress pituitary somatotrope hyperplasia and adenoma formation due to GHRH-receptor hyperactivation.

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All Publications

2012: Veronique Nogueira; Xiao-ding Peng; Neha Sarvepalli; Nahum Sonenberg; Deepa Sundararajan; Jennifer M Kwan; Nissim Hay
Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis.
The EMBO journal 2012;31(5):1134-46.
2012: Pei-Zhang Xu; Mei-Ling Chen; S-M Jeon; Xiao-ding Peng; Nissim Hay
The effect Akt2 deletion on tumor development in Pten(+/-) mice.
Oncogene 2012;31(4):518-26.
2009: Raul M Luque; Beatriz S Soares; Xiao-ding Peng; Sonia Krishnan; Jose Cordoba; Lawrence A Frohman; Rhonda D Kineman
Use of the metallothionein promoter-human growth hormone-releasing hormone (GHRH) mouse to identify regulatory pathways that suppress pituitary somatotrope hyperplasia and adenoma formation due to GHRH-receptor hyperactivation.
Endocrinology 2009;150(7):3177-85.
2009: William S Chen; Xiao-ding Peng; Yong Wang; Pei-Zhang Xu; Mei-Ling Chen; Yongmei Luo; Sang-Min Jeon; Kevin Coleman; Wanda M Haschek; Joseph Bass; Louis H Philipson; Nissim Hay
Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice.
Molecular and cellular biology 2009;29(11):3151-62.
2006: Jennifer E Skeen; Prashanth T Bhaskar; Chia-Chen Chen; William S Chen; Xiao-ding Peng; Veronique Nogueira; Annett Hahn-Windgassen; Hiroaki Kiyokawa; Nissim Hay
Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner.
Cancer cell 2006;10(4):269-80.
2006: Aleksandra Stojanovic; Jasna A Marjanovic; Viktor Brovkovych; Xiao-ding Peng; Nissim Hay; Randal A Skidgel; Xiaoping Du
A phosphoinositide 3-kinase-AKT-nitric oxide-cGMP signaling pathway in stimulating platelet secretion and aggregation.
The Journal of biological chemistry 2006;281(24):16333-9.
2006: Mei-Ling Chen; Pei-Zhang Xu; Xiao-ding Peng; William S Chen; Grace Guzman-Hartman; Ximing Yang; Antonio Di Cristofano; Pier Paolo Pandolfi; Nissim Hay
The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice.
Genes & development 2006;20(12):1569-74.
2005: Seungjoon Park; Xiao-ding Peng; Lawrence A Frohman; Rhonda D Kineman
Expression analysis of hypothalamic and pituitary components of the growth hormone axis in fasted and streptozotocin-treated neuropeptide Y (NPY)-intact (NPY+/+) and NPY-knockout (NPY-/-) mice.
Neuroendocrinology 2005;81(6):360-71.
2004: Raul M Luque; Rhonda D Kineman; Seungjoon Park; Xiao-ding Peng; Francisco Gracia-Navarro; Justo P Castaño; Maria M Malagon
Homologous and heterologous regulation of pituitary receptors for ghrelin and growth hormone-releasing hormone.
Endocrinology 2004;145(7):3182-9.
2004: Raul M Luque; Seungjoon Park; Xiao-ding Peng; E Delgado; Francisco Gracia-Navarro; Rhonda D Kineman; María M Malagón; Justo P Castaño
Homologous and heterologous in vitro regulation of pig pituitary somatostatin receptor subtypes, sst1, sst2 and sst5 mRNA.
Journal of molecular endocrinology 2004;32(2):437-48.
2003: Xiao-ding Peng; Pei-Zhang Xu; Mei-Ling Chen; Annett Hahn-Windgassen; Jennifer E Skeen; Joel Jacobs; Deepa Sundararajan; William S Chen; Susan E Crawford; Kevin G Coleman; Nissim Hay
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.
Genes & development 2003;17(11):1352-65.
2001: Kristina Wallenius; Klara Sjögren; Xiao-ding Peng; S Park; Ville Wallenius; Jun-Li Liu; M Umaerus; H Wennbo; Olle G P Isaksson; Lawrence A Frohman; Rhonda D Kineman; Claes Ohlsson; John-Olov Jansson
Liver-derived IGF-I regulates GH secretion at the pituitary level in mice.
Endocrinology 2001;142(11):4762-70.
2001: Xiao-ding Peng; Seungjoon Park; Mônica R Gadelha; Karen T Coschigano; John J Kopchick; Lawrence A Frohman; Rhonda D Kineman
The growth hormone (GH)-axis of GH receptor/binding protein gene-disrupted and metallothionein-human GH-releasing hormone transgenic mice: hypothalamic neuropeptide and pituitary receptor expression in the absence and presence of GH feedback.
Endocrinology 2001;142(3):1117-23.
2000: LT Teixeira; Hiroaki Kiyokawa; Xiao-ding Peng; Konstantin Christov-Tzelkov; Lawrence A Frohman; Rhonda D Kineman
p27Kip1-deficient mice exhibit accelerated growth hormone-releasing hormone (GHRH)-induced somatotrope proliferation and adenoma formation.
Oncogene 2000;19(15):1875-84.