Botond Penke

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Huszár József; Timár Zoltán; Bogár Ferenc; Penke Botond; Kiss Róbert; Szalai Krisztina Katalin; Schmidt Eva; Papp Andrea; Keseru György
Aspartic acid scaffold in bradykinin B1 antagonists.
Minkeviciene Rimante; Rheims Sylvain; Dobszay Marton B; Zilberter Misha; Hartikainen Jarmo; Fülöp Lívia; Penke Botond; Zilberter Yuri; Harkany Tibor; Pitkänen Asla; Tanila Heikki
Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy.
Juhász Gábor; Márki Arpád; Vass Gabriella; Fülöp Lívia; Budai Dénes; Penke Botond; Falkay György; Szegedi Viktor
An intraperitoneally administered pentapeptide protects against Abeta (1-42) induced neuronal excitation in vivo.

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2009: Huszár József; Timár Zoltán; Bogár Ferenc; Penke Botond; Kiss Róbert; Szalai Krisztina Katalin; Schmidt Eva; Papp Andrea; Keseru György
Aspartic acid scaffold in bradykinin B1 antagonists.
Journal of peptide science : an official publication of the European Peptide Society 2009;15(6):423-34.
2009: Minkeviciene Rimante; Rheims Sylvain; Dobszay Marton B; Zilberter Misha; Hartikainen Jarmo; Fülöp Lívia; Penke Botond; Zilberter Yuri; Harkany Tibor; Pitkänen Asla; Tanila Heikki
Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(11):3453-62.
2009: Juhász Gábor; Márki Arpád; Vass Gabriella; Fülöp Lívia; Budai Dénes; Penke Botond; Falkay György; Szegedi Viktor
An intraperitoneally administered pentapeptide protects against Abeta (1-42) induced neuronal excitation in vivo.
Journal of Alzheimer's disease : JAD 2009;16(1):189-96.
2009: Masman Marcelo F; Rodríguez Ana M; Raimondi Marcela; Zacchino Susana A; Luiten Paul G M; Somlai Csaba; Kortvelyesi Tamas; Penke Botond; Enriz Ricardo D
Penetratin and derivatives acting as antifungal agents.
European journal of medicinal chemistry 2009;44(1):212-28.
2008: Juhász Gábor; Vass Gabriella; Bozsó Zsolt; Budai Dénes; Penke Botond; Szegedi Viktor
Integrin activation modulates NMDA and AMPA receptor function of CA1 cells in a dose-related fashion in vivo.
Brain research 2008;1233():20-6.
2008: Karsai Arpád; Murvai Unige; Soós Katalin; Penke Botond; Kellermayer Miklós S Z
Oriented epitaxial growth of amyloid fibrils of the N27C mutant beta 25-35 peptide.
European biophysics journal : EBJ 2008;37(7):1133-7.
2008: Nijholt Ingrid M; Ostroveanu Anghelus; Scheper Wouter A; Penke Botond; Luiten Paul G M; Van der Zee Eddy A; Eisel Ulrich L M
Inhibition of PKA anchoring to A-kinase anchoring proteins impairs consolidation and facilitates extinction of contextual fear memories.
Neurobiology of learning and memory 2008;90(1):223-9.
2008: Huszár József; Timár Zoltán; Szalai Krisztina Katalin; Keseru György; Fülöp Ferenc; Penke Botond
Novel bradykinin-1 antagonists containing a (1,2,3,4-tetrahydro-isoquinolin-1-yl)acetic acid scaffold.
European journal of medicinal chemistry 2008;43(7):1552-8.
2008: Laczkó Ilona; Vass Elemér; Soós Katalin; Fülöp Livia; Zarándi Márta; Penke Botond
Aggregation of Abeta(1-42) in the presence of short peptides: conformational studies.
Journal of peptide science : an official publication of the European Peptide Society 2008;14(6):731-41.
2008: Verdier Yann; Földi István; Sergeant Nicolas; Fülöp Lívia; Penke Zsuzsa; Janáky Tamás; Szücs Mária; Penke Botond
Characterization of the interaction between Abeta 1-42 and glyceraldehyde phosphodehydrogenase.
Journal of peptide science : an official publication of the European Peptide Society 2008;14(6):755-62.
2008: Masman Marcelo F; Somlai Csaba; Garibotto Francisco M; Rodríguez Ana M; de la Iglesia Agustina; Zacchino Susana A; Penke Botond; Enriz Ricardo D
Structure-antifungal activity relationship of His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 and analogues.
Bioorganic & medicinal chemistry 2008;16(8):4347-58.
2008: Hunya Akos; Földi István; Szegedi Viktor; Soós Katalin; Zarándi Márta; Szabó Antal; Zádori Dénes; Penke Botond; Datki Zsolt L
Differences between normal and alpha-synuclein overexpressing SH-SY5Y neuroblastoma cells after Abeta(1-42) and NAC treatment.
Brain research bulletin 2008;75(5):648-54.
2008: Hetényi Anasztázia; Fülöp Lívia; Martinek Tamás A; Wéber Edit; Soós Katalin; Penke Botond
Ligand-induced flocculation of neurotoxic fibrillar Abeta(1-42) by noncovalent crosslinking.
Chembiochem : a European journal of chemical biology 2008;9(5):748-57.
2008: Kellermayer Miklós S Z; Karsai Arpád; Benke Margit; Soós Katalin; Penke Botond
Stepwise dynamics of epitaxially growing single amyloid fibrils.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(1):141-4.
2007: Zádori Dénes; Datki Zsolt; Penke Botond
[The role of chronic brain hypoperfusion in the pathogenesis of Alzheimer's disease--facts and hypotheses]
Ideggyógyászati szemle 2007;60(11-12):428-37.
2007: Leitgeb Balázs; Kerényi Adám; Bogár Ferenc; Paragi Gábor; Penke Botond; Rákhely Gábor
Studying the structural properties of polyalanine and polyglutamine peptides.
Journal of molecular modeling 2007;13(11):1141-50.
2007: Annaházi Anita; Mracskó Eva; Süle Zoltán; Karg Eszter; Penke Botond; Bari Ferenc; Farkas Eszter
Pre-treatment and post-treatment with alpha-tocopherol attenuates hippocampal neuronal damage in experimental cerebral hypoperfusion.
European journal of pharmacology 2007;571(2-3):120-8.
2007: Datki Zsolt L; Hunya Akos; Penke Botond
A novel and simple fluorescence method for the measurement of presynaptic vesicular zinc release in acute hippocampal slices with a fluorescence plate reader.
Brain research bulletin 2007;74(1-3):183-7.
2007: Sipos E; Kurunczi A; Kasza A; Horváth J; Felszeghy K; Laroche S; Toldi J; Párducz A; Penke B; Penke Z
Beta-amyloid pathology in the entorhinal cortex of rats induces memory deficits: implications for Alzheimer's disease.
Neuroscience 2007;147(1):28-36.
2007: Hartai Zsuzsanna; Klivenyi Peter; Janaky Tamas; Penke Botond; Dux Laszlo; Vecsei Laszlo
Peripheral kynurenine metabolism in focal dystonia.
Medicinal chemistry (Shariqah (United Arab Emirates)) 2007;3(3):285-8.
2007: Molnár Joseph; Engi Helga; Mándi Yvette; Somlai Csaba; Penke Botond; Szabó Andrea; Orosz Antal
Effects of nontoxic heat shock protein 90 inhibitor peptide derivatives on reversal of MDR of tumor cells.
In vivo (Athens, Greece) 2007;21(2):429-33.
2007: Zarándi Márta; Soós Katalin; Fülöp Lívia; Bozsó Zsolt; Datki Zsolt; Tóth Gábor K; Penke Botond
Synthesis of Abeta[1-42] and its derivatives with improved efficiency.
Journal of peptide science : an official publication of the European Peptide Society 2007;13(2):94-9.
2007: Hartai Zsuzsanna; Juhász Anna; Rimanóczy Agnes; Janáky Tamás; Donkó Teodóra; Dux László; Penke Botond; Tóth Gábor K; Janka Zoltán; Kálmán János
Decreased serum and red blood cell kynurenic acid levels in Alzheimer's disease.
Neurochemistry international 2007;50(2):308-13.
2007: Walter Silke; Letiembre Maryse; Liu Yang; Heine Holger; Penke Botond; Hao Wenlin; Bode Barbara; Manietta Nicole; Walter Jessica; Schulz-Schuffer Walter; Fassbender Klaus
Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;20(6):947-56.
2006: Masman Marcelo F; Rodríguez Ana M; Svetaz Laura; Zacchino Susana A; Somlai Csaba; Csizmadia Imre G; Penke Botond; Enriz Ricardo D
Synthesis and conformational analysis of His-Phe-Arg-Trp-NH2 and analogues with antifungal properties.
Bioorganic & medicinal chemistry 2006;14(22):7604-14.
2006: Karsai A; Mártonfalvi Zs; Nagy A; Grama L; Penke B; Kellermayer M S Z
Mechanical manipulation of Alzheimer's amyloid beta1-42 fibrils.
Journal of structural biology 2006;155(2):316-26.
2006: Szegedi Viktor; Juhász Gábor; Rózsa Eva; Juhász-Vedres Gabriella; Datki Zsolt; Fülöp Lívia; Bozsó Zsolt; Lakatos Andrea; Laczkó Ilona; Farkas Tamás; Kis Zsolt; Tóth Géza; Soós Katalin; Zarándi Márta; Budai Dénes; Toldi József; Penke Botond
Endomorphin-2, an endogenous tetrapeptide, protects against Abeta1-42 in vitro and in vivo.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(8):1191-3.
2006: Letoha Tamás; Kusz Erzsébet; Pápai Gábor; Szabolcs Annamária; Kaszaki József; Varga Ilona; Takács Tamás; Penke Botond; Duda Erno
In vitro and in vivo nuclear factor-kappaB inhibitory effects of the cell-penetrating penetratin peptide.
Molecular pharmacology 2006;69(6):2027-36.
2006: Zana Marianna; Juhász Anna; Rimanóczy Agnes; Bjelik Annamária; Baltás Eszter; Ocsovszki Imre; Boda Krisztina; Penke Botond; Dobozy Attila; Kemény Lajos; Janka Zoltán; Kálmán János
Alzheimer's lymphocytes are resistant to ultraviolet B-induced apoptosis.
Neurobiology of aging 2006;27(6):831-4.
2006: Law Jacqueline M S; Szori Milan; Izsak Robert; Penke Botond; Csizmadia Imre G; Viskolcz Bela
Folded and unfolded conformations of the omega-3 polyunsaturated fatty acid family: ch(3)ch(2)[ch=chch(2)](b)[ch(2)](m)cooh: first principles study.
The journal of physical chemistry. A 2006;110(18):6100-11.
2006: Shemer Isaac; Holmgren Carl; Min Rogier; Fülöp Livia; Zilberter Misha; Sousa Kyle M; Farkas Tamás; Härtig Wolfgang; Penke Botond; Burnashev Nail; Tanila Heikki; Zilberter Yuri; Harkany Tibor
Non-fibrillar beta-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors.
The European journal of neuroscience 2006;23(8):2035-47.
2006: Hetényi Csaba; Paragi Gábor; Maran Uko; Timár Zoltán; Karelson Mati; Penke Botond
Combination of a modified scoring function with two-dimensional descriptors for calculation of binding affinities of bulky, flexible ligands to proteins.
Journal of the American Chemical Society 2006;128(4):1233-9.
2006: Kálmán János; Juhász Anna; Bogáts Gábor; Babik Barna; Rimanóczy Agnes; Janka Zoltán; Penke Botond; Palotás András
Elevated levels of inflammatory biomarkers in the cerebrospinal fluid after coronary artery bypass surgery are predictors of cognitive decline.
Neurochemistry international 2006;48(3):177-80.
2006: Orosz Antal; Szabo Andrea; Szeman Gabriella; Janaky Tamas; Somlai Csaba; Penke Botond; Bodor Andrea; Perczel Andras
Novel nontoxic heat shock protein 90 inhibitors having selective antiproliferative effect.
The international journal of biochemistry & cell biology 2006;38(8):1352-62.
2005: Hartai Zsuzsanna; Klivenyi Peter; Janaky Tamas; Penke Botond; Dux Laszlo; Vecsei Laszlo
Kynurenine metabolism in plasma and in red blood cells in Parkinson's disease.
Journal of the neurological sciences 2005;239(1):31-5.
2005: Letoha Tamás; Gaál Szilvia; Somlai Csaba; Venkei Zsolt; Glavinas Hristos; Kusz Erzsébet; Duda Ernö; Czajlik András; Peták Ferenc; Penke Botond
Investigation of penetratin peptides. Part 2. In vitro uptake of penetratin and two of its derivatives.
Journal of peptide science : an official publication of the European Peptide Society 2005;11(12):805-11.
2005: Karsai A; Nagy A; Kengyel A; Mártonfalvi Z; Grama L; Penke B; Kellermayer M S Z
Effect of lysine-28 side-chain acetylation on the nanomechanical behavior of alzheimer amyloid beta25-35 fibrils.
Journal of chemical information and modeling 2005;45(6):1641-6.
2005: Szegedi Viktor; Juhász Gábor; Budai Dénes; Penke Botond
Divergent effects of Abeta1-42 on ionotropic glutamate receptor-mediated responses in CA1 neurons in vivo.
Brain research 2005;1062(1-2):120-6.
2005: Letoha Tamás; Somlai Csaba; Takács Tamás; Szabolcs Annamária; Rakonczay Zoltán; Jármay Katalin; Szalontai Tamás; Varga Ilona; Kaszaki József; Boros Imre; Duda Erno; Hackler László; Kurucz István; Penke Botond
The proteasome inhibitor MG132 protects against acute pancreatitis.
Free radical biology & medicine 2005;39(9):1142-51.
2005: Fehér Liliána Z; Kálmán János; Puskás László G; Gyülvészi Gábor; Kitajka Klára; Penke Botond; Palotás Miklós; Samarova Elena I; Molnár József; Zvara Agnes; Matin Keyvan; Bódi Nikoletta; Hugyecz Marietta; Pákáski Magdolna; Bjelik Annamária; Juhász Anna; Bogáts Gábor; Janka Zoltán; Palotás András
Impact of haloperidol and risperidone on gene expression profile in the rat cortex.
Neurochemistry international 2005;47(4):271-80.
2005: Bogár F; Szekeres Zs; Bartha F; Penke B; Ladik J
Density functional study of infinite polyserine chains.
Physical chemistry chemical physics : PCCP 2005;7(15):2965-9.
2005: Hartai Z; Klivenyi P; Janaky T; Penke B; Dux L; Vecsei L
Kynurenine metabolism in multiple sclerosis.
Acta neurologica Scandinavica 2005;112(2):93-6.
2005: Verdier Yann; Huszár Emoke; Penke Botond; Penke Zsuzsa; Woffendin Gary; Scigelova Michaela; Fülöp Lívia; Szucs Mária; Medzihradszky Katalin; Janáky Tamás
Identification of synaptic plasma membrane proteins co-precipitated with fibrillar beta-amyloid peptide.
Journal of neurochemistry 2005;94(3):617-28.
2005: Liu Yang; Walter Silke; Stagi Massimiliano; Cherny Dmitry; Letiembre Maryse; Schulz-Schaeffer Walter; Heine Holger; Penke Botond; Neumann Harald; Fassbender Klaus
LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide.
Brain : a journal of neurology 2005;128(Pt 8):1778-89.
2005: Chass Gregory A; Mirasol Rei S; Setiadi David H; Tang Ting-Hua; Chin Wutharath; Mons Michel; Dimicoli Iliana; Dognon Jean-Pierre; Viskolcz Bela; Lovas Sandor; Penke Botond; Csizmadia Imre G
Characterization of the conformational probability of N-acetyl-phenylalanyl-NH2 by RHF, DFT, and MP2 computation and AIM analyses, confirmed by jet-cooled infrared data.
The journal of physical chemistry. A 2005;109(24):5289-302.
2005: Bogár Ferenc; Leitgeb Balázs; Paragi Gábor; Orosz Antal; Penke Botond
Comparative study of SP[6-11] and its analogs using simulated annealing.
Biopolymers 2005;78(1):35-45.
2005: Szegedi V; Fülöp L; Farkas T; Rózsa E; Robotka H; Kis Z; Penke Z; Horváth S; Molnár Z; Datki Z; Soós K; Toldi J; Budai D; Zarándi M; Penke B
Pentapeptides derived from Abeta 1-42 protect neurons from the modulatory effect of Abeta fibrils--an in vitro and in vivo electrophysiological study.
Neurobiology of disease 2005;18(3):499-508.
2005: Sahai Michelle A; Kehoe Tara A K; Koo Joseph C P; Setiadi David H; Chass Gregory A; Viskolcz Bela; Penke Botond; Pai Emil F; Csizmadia Imre G
First principle computational study on the full conformational space of L-proline diamides.
The journal of physical chemistry. A 2005;109(11):2660-79.
2005: Kellermayer Miklós S Z; Grama László; Karsai Arpád; Nagy Attila; Kahn Amram; Datki Zsolt L; Penke Botond
Reversible mechanical unzipping of amyloid beta-fibrils.
The Journal of biological chemistry 2005;280(9):8464-70.
2005: Lain Enzo; Penke Botond; Delacourte André; Gündisch Daniela; Schröder Hannsjörg; Witter Brigitte
Effects of Abeta1-42 fibrils and of the tetrapeptide Pr-IIGL on the phosphorylation state of the tau-protein and on the alpha7 nicotinic acetylcholine receptor in vitro.
The European journal of neuroscience 2005;21(4):879-88.
2005: Letoha Tamas; Somlai Csaba; Takacs Tamas; Szabolcs Annamaria; Jarmay Katalin; Rakonczay Zoltan; Hegyi Peter; Varga Ilona; Kaszaki Jozsef; Krizbai Istvan; Boros Imre; Duda Erno; Kusz Erzsebet; Penke Botond
A nuclear import inhibitory peptide ameliorates the severity of cholecystokinin-induced acute pancreatitis.
World journal of gastroenterology : WJG 2005;11(7):990-9.
2004: Datki Zsolt; Papp Rita; Zádori Dénes; Soós Katalin; Fülöp Lívia; Juhász Anna; Laskay Gábor; Hetényi Csaba; Mihalik Erzsébet; Zarándi Márta; Penke Botond
In vitro model of neurotoxicity of Abeta 1-42 and neuroprotection by a pentapeptide: irreversible events during the first hour.
Neurobiology of disease 2004;17(3):507-15.
2004: Palotás Miklós; Palotás András; Puskás László G; Kitajka Klára; Pákáski Magdolna; Janka Zoltán; Molnár József; Penke Botond; Kálmán János
Gene expression profile analysis of the rat cortex following treatment with imipramine and citalopram.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2004;7(4):401-13.
2004: Fülöp Lívia; Zarándi Márta; Datki Zsolt; Soós Katalin; Penke Botond
Beta-amyloid-derived pentapeptide RIIGLa inhibits Abeta(1-42) aggregation and toxicity.
Biochemical and biophysical research communications 2004;324(1):64-9.
2004: Palotás András; Puskás László G; Kitajka Klára; Palotás Miklós; Molnár József; Pákáski Magdolna; Janka Zoltán; Penke Botond; Kálmán János
Altered response to mirtazapine on gene expression profile of lymphocytes from Alzheimer's patients.
European journal of pharmacology 2004;497(3):247-54.
2004: Palotás András; Puskás László G; Kitajka Klára; Palotás Miklós; Molnár József; Pákáski Magdolna; Janka Zoltán; Penke Botond; Kálmán János
The effect of citalopram on gene expression profile of Alzheimer lymphocytes.
Neurochemical research 2004;29(8):1563-70.
2004: Palotás A; Penke B; Palotás M; Kenderessy A Sz; Kemény L; Kis E; Vincze G; Janka Z; Kálmán J
Haloperidol attenuates beta-amyloid-induced calcium imbalance in human fibroblasts.
Skin pharmacology and physiology 2004;17(4):195-9.
2004: Molnár Zsolt; Soós Katalin; Lengyel Imre; Penke Botond; Szegedi Viktor; Budai Dénes
Enhancement of NMDA responses by beta-amyloid peptides in the hippocampus in vivo.
Neuroreport 2004;15(10):1649-52.
2004: Kálmán János; Juhász Anna; Rakonczay Zoltán; Abrahám György; Zana Marianna; Boda Krisztina; Farkas Tibor; Penke Botond; Janka Zoltán
Increased serum butyrylcholinesterase activity in type IIb hyperlipidaemic patients.
Life sciences 2004;75(10):1195-204.
2004: Molnár Zs; Kovács P; Laczkó I; Soós K; Fülöp L; Penke B; Lengyel I
Enhanced G-protein activation by a mixture of Abeta(25-35), Abeta(1-40/42) and zinc.
Journal of neurochemistry 2004;89(5):1215-23.
2004: Verdier Yann; Zarándi Márta; Penke Botond
Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease.
Journal of peptide science : an official publication of the European Peptide Society 2004;10(5):229-48.
2004: Kálmán János; Juhász Anna; Janka Zoltán; Rakonczay Zoltán; Abrahám György; Boda Krisztina; Farkas Tibor; Penke Botond
Serum butyrylcholinesterase activity in hyperlipidaemia.
Atherosclerosis 2004;173(1):145-6.
2004: Palotás András; Penke Botond; Kemény Lajos; Janka Zoltán; Kálmán János
A chapter in the unity of variety--calcium is the sole author?
Brain research 2004;1000(1-2):57-9.
2004: Verdier Yann; Penke Botond
Binding sites of amyloid beta-peptide in cell plasma membrane and implications for Alzheimer's disease.
Current protein & peptide science 2004;5(1):19-31.
2004: Füvesi Judit; Somlai Csaba; Németh Hajnalka; Varga Hedvig; Kis Zsolt; Farkas Tamás; Károly Norbert; Dobszay Márton; Penke Zsuzsa; Penke Botond; Vécsei László; Toldi József
Comparative study on the effects of kynurenic acid and glucosamine-kynurenic acid.
Pharmacology, biochemistry, and behavior 2004;77(1):95-102.
2004: Fassbender K; Walter S; Kühl S; Landmann R; Ishii K; Bertsch T; Stalder A K; Muehlhauser F; Liu Y; Ulmer A J; Rivest S; Lentschat A; Gulbins E; Jucker M; Staufenbiel M; Brechtel K; Walter J; Multhaup G; Penke B; Adachi Y; Hartmann T; Beyreuther K
The LPS receptor (CD14) links innate immunity with Alzheimer's disease.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):203-5.
2003: Datki Zsolt; Juhász Anna; Gálfi Márta; Soós Katalin; Papp Rita; Zádori Dénes; Penke Botond
Method for measuring neurotoxicity of aggregating polypeptides with the MTT assay on differentiated neuroblastoma cells.
Brain research bulletin 2003;62(3):223-9.
2003: Erchegyi Judit; Penke Botond; Simon Lajos; Michaelson Scott; Wenger Sandra; Waser Beatrice; Cescato Renzo; Schaer Jean-Claude; Reubi Jean Claude; Rivier Jean
Novel sst(4)-selective somatostatin (SRIF) agonists. 2. Analogues with beta-methyl-3-(2-naphthyl)alanine substitutions at position 8.
Journal of medicinal chemistry 2003;46(26):5587-96.
2003: Palotás András; Pákáski Magdolna; Palotás Miklós; Hugyecz Marietta; Molnár József; Penke Botond; Janka Zoltán; Kálmán János
Effect of haloperidol and risperidone on amyloid precursor protein levels in vivo.
Brain research bulletin 2003;62(2):93-9.
2003: Letoha T; Gaál S; Somlai C; Czajlik A; Perczel A; Penke B
Membrane translocation of penetratin and its derivatives in different cell lines.
Journal of molecular recognition : JMR 2003;16(5):272-9.
2003: Palotás András; Kálmán János; Palotás Miklós; Kemény Lajos; Janka Zoltán; Penke Botond
Long-term exposition of cells to beta-amyloid results in decreased intracellular calcium concentration.
Neurochemistry international 2003;42(7):543-7.
2003: Högyes E; Nyakas C; Kiliaan A; Farkas T; Penke B; Luiten P G M
Neuroprotective effect of developmental docosahexaenoic acid supplement against excitotoxic brain damage in infant rats.
Neuroscience 2003;119(4):999-1012.
2003: Farkas Ibolya G; Czigner Andrea; Farkas Eszter; Dobó Endre; Soós Katalin; Penke Botond; Endrész Valéria; Mihály András
Beta-amyloid peptide-induced blood-brain barrier disruption facilitates T-cell entry into the rat brain.
Acta histochemica 2003;105(2):115-25.
2002: Palotás András; Kálmán János; Palotás Miklós; Matin Keyvan; Szentpáli Károly; Paszt Attila; Janka Zoltán; Penke Botond
Whole blood samples from Alzheimer patients and control donors demonstrate fluorimetric differences.
Neurochemical research 2002;27(12):1589-91.
2002: DeMager Peter P; Penke Botond; Walter Regina; Harkany Tibor; Härtignny Wolfgang
Pathological peptide folding in Alzheimer's disease and other conformational disorders.
Current medicinal chemistry 2002;9(19):1763-80.
2002: Palotás András; Kálmán János; Palotás Miklós; Juhász Anna; Janka Zoltán; Penke Botond
Fibroblasts and lymphocytes from Alzheimer patients are resistant to beta-amyloid-induced increase in the intracellular calcium concentration.
Progress in neuro-psychopharmacology & biological psychiatry 2002;26(5):971-4.
2002: Palotás András; Kálmán János; Palotás Miklós; Juhász Anna; Janka Zoltán; Penke Botond
Beta-amyloid-induced increase in the resting intracellular calcium concentration gives support to tell Alzheimer lymphocytes from control ones.
Brain research bulletin 2002;58(2):203-5.
2002: Palotás András; Kálmán János; Laskay Gábor; Juhász Anna; Janka Zoltán; Penke Botond
[Change of fibroblast calcium levels caused by beta-amyloid peptide in Alzheimer disease]
Ideggyógyászati szemle 2002;55(5-6):164-7.
2002: Harkany Tibor; Varga Csaba; Grosche Jens; Mulder Jan; Luiten Paul G M; Hortobágyi Tibor; Penke Botond; Härtig Wolfgang
Distinct subsets of nucleus basalis neurons exhibit similar sensitivity to excitotoxicity.
Neuroreport 2002;13(6):767-72.
2002: Hetényi Csaba; Körtvélyesi Tamás; Penke Botond
Mapping of possible binding sequences of two beta-sheet breaker peptides on beta amyloid peptide of Alzheimer's disease.
Bioorganic & medicinal chemistry 2002;10(5):1587-93.
2002: Czajlik András; Meskó Eszter; Penke Botond; Perczel András
Investigation of penetratin peptides. Part 1. The environment dependent conformational properties of penetratin and two of its derivatives.
Journal of peptide science : an official publication of the European Peptide Society 2002;8(4):151-71.
2002: Hetényi Csaba; Szabó Zoltán; Klement Eva; Datki Zsolt; Körtvélyesi Tamás; Zarándi Márta; Penke Botond
Pentapeptide amides interfere with the aggregation of beta-amyloid peptide of Alzheimer's disease.
Biochemical and biophysical research communications 2002;292(4):931-6.
2002: Härtig Wolfgang; Bauer Andreas; Brauer Kurt; Grosche Jens; Hortobágyi Tibor; Penke Botond; Schliebs Reinhard; Harkany Tibor
Functional recovery of cholinergic basal forebrain neurons under disease conditions: old problems, new solutions?
Reviews in the neurosciences 2002;13(2):95-165.
2001: Lázár Z; Shahbazian A; Benkó R; Tóth G; Penke B; Barthó L; Holzer P
PACAP-(6-38) inhibits the effects of vasoactive intestinal polypeptide, but not PACAP, on the small intestinal circular muscle.
European journal of pharmacology 2001;431(2):259-64.
2001: Fülöp L; Penke B; Zarándi M
Synthesis and fluorescent labeling of beta-amyloid peptides.
Journal of peptide science : an official publication of the European Peptide Society 2001;7(8):397-401.
2001: Harkany T; O'Mahony S; Keijser J; Kelly J P; Kónya C; Borostyánkoi Z A; Görcs T J; Zarándi M; Penke B; Leonard B E; Luiten P G
Beta-amyloid(1-42)-induced cholinergic lesions in rat nucleus basalis bidirectionally modulate serotonergic innervation of the basal forebrain and cerebral cortex.
Neurobiology of disease 2001;8(4):667-78.
2001: Palotás A; Kálmán J; Laskay G; Juhász A; Janka Z; Penke B
Comparative studies on [Ca2+]i-level of fibroblasts from Alzheimer patients and control individuals.
Neurochemical research 2001;26(7):817-20.
2001: Kupihár Z; Schmél Z; Kele Z; Penke B; Kovács L
Synthesis and application of a novel, crystalline phosphoramidite monomer with thiol terminus, suitable for the synthesis of DNA conjugates.
Bioorganic & medicinal chemistry 2001;9(5):1241-7.
2000: Harkany T; Abrahám I; Timmerman W; Laskay G; Tóth B; Sasvári M; Kónya C; Sebens J B; Korf J; Nyakas C; Zarándi M; Soós K; Penke B; Luiten P G
beta-amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis.
The European journal of neuroscience 2000;12(8):2735-45.
2000: Ishii K; Muelhauser F; Liebl U; Picard M; Kühl S; Penke B; Bayer T; Wiessler M; Hennerici M; Beyreuther K; Hartmann T; Fassbender K
Subacute NO generation induced by Alzheimer's beta-amyloid in the living brain: reversal by inhibition of the inducible NO synthase.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(11):1485-9.
2000: Abrahám I; Harkany T; Horvath K M; Veenema A H; Penke B; Nyakas C; Luiten P G
Chronic corticosterone administration dose-dependently modulates Abeta(1-42)- and NMDA-induced neurodegeneration in rat magnocellular nucleus basalis.
Journal of neuroendocrinology 2000;12(6):486-94.
2000: Lénárd L; Lázár Z; Benkó R; Szigeti R; Báthori Z; Tóth G K; Penke B; Barthó L
Inhibitory effect of PACAP(6-38) on relaxations induced by PACAP, VIP and non-adrenergic, non-cholinergic nerve stimulation in the guinea-pig taenia caeci.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(5):492-7.
2000: Harkany T; Penke B; Luiten P G
beta-Amyloid excitotoxicity in rat magnocellular nucleus basalis. Effect of cortical deafferentation on cerebral blood flow regulation and implications for Alzheimer's disease.
Annals of the New York Academy of Sciences 2000;903():374-86.
2000: Barthó L; Lázár Z; Lénárd L; Benkó R; Tóth G; Penke B; Szolcsányi J; Maggi C A
Evidence for the involvement of ATP, but not of VIP/PACAP or nitric oxide, in the excitatory effect of capsaicin in the small intestine.
European journal of pharmacology 2000;392(3):183-8.
2000: Kasa P; Papp H; Kovacs I; Forgon M; Penke B; Yamaguchi H
Human amyloid-beta1-42 applied in vivo inhibits the fast axonal transport of proteins in the sciatic nerve of rat.
Neuroscience letters 2000;278(1-2):117-9.
2000: Harkany T; Abrahám I; Kónya C; Nyakas C; Zarándi M; Penke B; Luiten P G
Mechanisms of beta-amyloid neurotoxicity: perspectives of pharmacotherapy.
Reviews in the neurosciences 2000;11(4):329-82.
1999: Szabó Z; Klement E; Jost K; Zarándi M; Soós K; Penke B
An FT-IR study of the beta-amyloid conformation: standardization of aggregation grade.
Biochemical and biophysical research communications 1999;265(2):297-300.
1999: Harkany T; Hortobágyi T; Sasvári M; Kónya C; Penke B; Luiten P G; Nyakas C
Neuroprotective approaches in experimental models of beta-amyloid neurotoxicity: relevance to Alzheimer's disease.
Progress in neuro-psychopharmacology & biological psychiatry 1999;23(6):963-1008.
1999: Harkany T; Abrahám I; Laskay G; Timmerman W; Jost K; Zarándi M; Penke B; Nyakas C; Luiten P G
Propionyl-IIGL tetrapeptide antagonizes beta-amyloid excitotoxicity in rat nucleus basalis.
Neuroreport 1999;10(8):1693-8.
1999: Harkany T; Mulder J; Sasvári M; Abrahám I; Kónya C; Zarándi M; Penke B; Luiten P G; Nyakas C
N-Methyl-D-aspartate receptor antagonist MK-801 and radical scavengers protect cholinergic nucleus basalis neurons against beta-amyloid neurotoxicity.
Neurobiology of disease 1999;6(2):109-21.
1999: Laskay G; Zarándi M; Jost K; Penke B; Bálint E; Ocsovszki I; Tarcsa M; Várszegi S; Gulya K
beta-Amyloid[1-40]-induced early hyperpolarization in M26-1F cells, an immortalized rat striatal cell line.
Neurobiology (Budapest, Hungary) 1999;7(4):431-6.
1999: Kovács A; Telegdy G; Tóth G; Penke B
Neurotransmitter-mediated open-field behavioral action of CGRP.
Life sciences 1999;64(9):733-40.
1998: Jancsó G; Domoki F; Sántha P; Varga J; Fischer J; Orosz K; Penke B; Becskei A; Dux M; Tóth L
Beta-amyloid (1-42) peptide impairs blood-brain barrier function after intracarotid infusion in rats.
Neuroscience letters 1998;253(2):139-41.
1998: Pakaski M; Farkas Z; Kasa P; Forgon M; Papp H; Zarandi M; Penke B; Kasa P
Vulnerability of small GABAergic neurons to human beta-amyloid pentapeptide.
Brain research 1998;796(1-2):239-46.
1998: Torday L L; Pataricza J; Balogh G E; Zarándi M; Penke B; Papp J G
Endothelium-dependent vasorelaxant and anti-aggregatory effect and mechanism of action of some antifibrinogen RGD (Arg-Gly-Asp-containing) peptides.
The Journal of pharmacy and pharmacology 1998;50(6):667-71.
1998: Pataricza J; Penke B; Balogh G E; Papp J G
Polarographic detection of nitric oxide released from cardiovascular compounds in aqueous solutions.
Journal of pharmacological and toxicological methods 1998;39(2):91-5.
1998: Harkany T; O'Mahony S; Kelly J P; Soós K; Törõ I; Penke B; Luiten P G; Nyakas C; Gulya K; Leonard B E
Beta-amyloid(Phe(SO3H)24)25-35 in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cortical cholinergic innervation.
Behavioural brain research 1998;90(2):133-45.
1998: Kasa P; Penke B; Pakaski M
Amyloid beta-peptide treatment induces a redistribution of acetylcholinesterase within the enzyme-containing neurons in in vitro tissue cultures.
Neurobiology (Budapest, Hungary) 1998;6(3):369-71.
1998: Forgon M; Farkas Z; Gulya K; Pakaski M; Penke B; Kasa P
Amyloid beta-peptide and its fragments induce acetylcholine release in in vitro basal forebrain tissue slices of rat brain, but do not affect the choline uptake.
Neurobiology (Budapest, Hungary) 1998;6(3):359-61.
1998: O'Mahony S; Harkany T; Rensink A A; Abrahám I; De Jong G I; Varga J L; Zarándi M; Penke B; Nyakas C; Luiten P G; Leonard B E
Beta-amyloid-induced cholinergic denervation correlates with enhanced nitric oxide synthase activity in rat cerebral cortex: reversal by NMDA receptor blockade.
Brain research bulletin 1998;45(4):405-11.
1997: Biró E; Penke B; Telegdy G
Role of different neurotransmitter systems in the cholecystokinin octapeptide-induced anxiogenic response in rats.
Neuropeptides 1997;31(3):281-5.
1997: Laskay G; Zarándi M; Varga J; Jost K; Fónagy A; Torday C; Latzkovits L; Penke B
A putative tetrapeptide antagonist prevents beta-amyloid-induced long-term elevation of [Ca2+]i in rat astrocytes.
Biochemical and biophysical research communications 1997;235(3):479-81.
1997: Farkas Z; Pákáski M; Penke B; Kása P
Acetylcholine release induced in vitro by beta-amyloid and its fragments.
Neurobiology (Budapest, Hungary) 1997;5(1):59-61.
1996: Laczkó I; Vass E; Soós K; Varga J L; Száraz S; Hollósi M; Penke B
Ca(2+)- and Al(3+)-induced conformational transitions of amyloid fragment H-Ile-Ile-Gly-Leu-Met-NH2.
Archives of biochemistry and biophysics 1996;335(2):381-7.
1996: Pákáski M; Farkas Z; Soós K; Penke B; Kása P
Role of Leu(34)-Met(35) in neurotoxicity caused by human beta-amyloid (1-42) peptide in vitro.
Neurobiology (Budapest, Hungary) 1996;4(3):273-4.
1996: Kovács A; Telegdy G; Tóth G; Penke B
The involvement of nitric oxide (NO) in the CGRP-induced behavior of rats.
Peptides 1996;17(7):1183-7.
1995: Pataricza J; Toth G K; Penke B; Hohn J; Papp J G
Effect of selective inhibition of potassium channels on vasorelaxing response to cromakalim, nitroglycerin and nitric oxide of canine coronary arteries.
The Journal of pharmacy and pharmacology 1995;47(11):921-5.
1995: Harkany T; De Jong G I; Soós K; Penke B; Luiten P G; Gulya K
Beta-amyloid (1-42) affects cholinergic but not parvalbumin-containing neurons in the septal complex of the rat.
Brain research 1995;698(1-2):270-4.
1995: Harkany T; Lengyel Z; Soós K; Penke B; Luiten P G; Gulya K
Cholinotoxic effects of beta-amyloid (1-42) peptide on cortical projections of the rat nucleus basalis magnocellularis.
Brain research 1995;695(1):71-5.
1995: Tóth G K; Pataricza J; Janáky T; Mák M; Zarándi M; Papp J G; Penke B
Synthesis of two peptide scorpion toxins and their use to investigate the aortic tissue regulation.
Peptides 1995;16(7):1167-72.
1994: Rajnavölgyi E; Nagy Z; Kurucz I; Gogolák P; Tóth G K; Váradi G; Penke B; Tigyi Z; Hollósi M; Gergely J
T cell recognition of the posttranslationally cleaved intersubunit region of influenza virus hemagglutinin.
Molecular immunology 1994;31(18):1403-14.
1994: Laczkó I; Holly S; Kónya Z; Soós K; Varga J L; Hollósi M; Penke B
Conformational mapping of amyloid peptides from the putative neurotoxic 25-35 region.
Biochemical and biophysical research communications 1994;205(1):120-6.
1994: Nagy Z; Rajnavölgyi E; Hollósi M; Tóth G K; Váradi G; Penke B; Tóth I; Horváth A; Gergely J; Kurucz I
The intersubunit region of the influenza virus haemagglutinin is recognized by antibodies during infection.
Scandinavian journal of immunology 1994;40(3):281-91.
1994: Vecsernyés M; Török A; Jójárt I; Laczi F; Penke B; Julesz J
Specific radioimmunoassay of oxytocin in rat plasma.
Endocrine regulations 1994;28(3):145-50.
1994: Váradi G; Tóth G K; Penke B
A new synthesis of Rink's polymer, 4-(2',4'-dimethoxyphenylhydroxymethyl)phenoxymethylpolystyrene .
International journal of peptide and protein research 1994;43(1):29-30.
1993: Tóth G K; Váradi G; Nagy Z; Monostori E; Penke B; Hegedüs Z; Andó I; Fazekas G; Kurucz I; Mák M
Branched polypeptides as antigens for influenza virus hemagglutinin and T-cell receptor subunits.
Peptide research 1993;6(5):272-80.
1993: Biró E; Sarnyai Z; Penke B; Szabó G; Telegdy G
Role of endogenous corticotropin-releasing factor in mediation of neuroendocrine and behavioral responses to cholecystokinin octapeptide sulfate ester in rats.
Neuroendocrinology 1993;57(2):340-5.
1992: Sarnyai Z; Bíró E; Penke B; Telegdy G
The cocaine-induced elevation of plasma corticosterone is mediated by endogenous corticotropin-releasing factor (CRF) in rats.
Brain research 1992;589(1):154-6.
1992: Hollósi M; Ismail A A; Mantsch H H; Penke B; Varadi I G; Toth G K; Laczkó I; Kurucz I; Nagy Z; Fasman G D
Conformational and functional properties of peptides covering the intersubunit region of influenza virus hemagglutinin.
European journal of biochemistry / FEBS 1992;206(2):421-5.
1992: Bidzseranova A; Gueron J; Tóth G; Penke B; Telegdy G
Effect of atrial natriuretic peptide on dopa potentiation in mice.
Brain research bulletin 1992;28(5):767-8.
1992: Bidzseranova A; Gueron J; Tóth G; Penke B; Varga J; Telegdy G
Behavioral effects of atrial and brain natriuretic peptides in rats.
Neuroreport 1992;3(3):283-5.
1992: Bidzseranova A; Gueron J; Tóth G; Penke B; Telegdy G
Effect of atrial natriuretic peptide on apomorphine-induced stereotyped cage-climbing behavior in mice.
European journal of pharmacology 1992;211(3):411-4.
1992: Sarnyai Z; Höhn J; Szabó G; Penke B
Critical role of endogenous corticotropin-releasing factor (CRF) in the mediation of the behavioral action of cocaine in rats.
Life sciences 1992;51(26):2019-24.
1991: Bidzseranova A; Gueron J; Penke B; Telegdy G
The effects of atrial natriuretic peptide on active avoidance behavior in rats. The role of transmitters.
Pharmacology, biochemistry, and behavior 1991;40(1):61-4.
1991: Bidzseranova A; Penke B; Tóth G; Telegdy G
The effects of atrial natriuretic peptide on electroconvulsive shock-induced amnesia in rats. Transmitter-mediated action.
Neuropeptides 1991;19(2):103-6.
1989: László F; Pávó I; Penke B; Bálint G A
Protective effect of an orally administered, highly potent somatostatin analog (RC-121) against absolute ethanol-induced hemorrhagic erosions of the rat gastric mucosa.
Life sciences 1989;44(21):1573-8.
1989: László F; Pávó I; Penke B; Bálint G A
The cytoprotective effect of the desamino-D-Trp 7-10 fragment of somatostatin on ethanol-induced erosions in the rat stomach.
Acta physiologica Hungarica 1989;73(2-3):199-202.
1988: Laczi F; Vecsernyés M; Kovács G L; Penke B; Jójárt I; Janáky T; Telegdy G; László F A
The effect of atrial natriuretic factor on arginine-8-vasopressin and oxytocin levels in various brain regions and plasma.
Experimental and clinical endocrinology 1988;92(3):328-34.
1987: László F; Pávó I; Penke B; Bálint G A
The effects of somatostatin and some of its tetrapeptide fragments on ethanol-induced gastric mucosal erosion in rat.
Life sciences 1987;41(9):1123-6.
1987: Kádár T; Borda L; Zarándi M; Penke B; Kovács K; Telegdy G
Inhibition of electroshock-induced seizures by cholecystokinin-related peptides in mice.
Acta physiologica Hungarica 1987;69(1):43-50.
1986: Penke B; Zarándi M; Varga J R; Tóth G K; Kovács K; Szajáni B
Targeted immobilization of neurotransmitters and neuropeptides on agarose and on Acrylex polymers.
Journal of chromatography 1986;376():307-14.
1986: Kádár T; Penke B; Kovács K; Telegdy G
Inhibition of feeding by the C-terminal tetrapeptide fragment of cholecystokinin in a novel environment.
Neuropeptides 1986;7(2):97-108.
1985: Kádár T; Penke B; Pesti A; Telegdy G
Multiple treatment potentiates the anticonvulsive activity of cholecystokinin octapeptides.
Peptides 1985;6(6):1009-14.
1985: Kádár T; Borda L; Penke B; Kovács K; Telegdy G
Cataleptogenic and anticataleptic activity produced by cholecystokinin octapeptides in mice.
Neuropeptides 1985;6(3):259-68.
1985: Kádár T; Penke B; Kovács K; Telegdy G
Inhibition of haloperidol-induced catalepsy by cholecystokinin octapeptides after central administration to rats.
Neuropharmacology 1985;24(6):577-80.
1985: Kádár T; Penke B; Kovács K; Telegdy G
Depression of rat feeding in familiar and novel environment by sulfated and nonsulfated cholecystokinin octapeptide.
Physiology & behavior 1985;34(3):395-400.
1985: Penke B; Kovács G L; Zsigó J; Kádár T; Szabó G; Kovács K; Telegdy G
In vivo sulfation of cholecystokinin octapeptide. Possible interactions of the two forms of cholecystokinin with dopamine in the brain.
Annals of the New York Academy of Sciences 1985;448():293-305.
1984: Kádár T; Várszegi M; Sudakov S K; Penke B; Telegdy G
Changes in brain monoamine levels of rats during cholecystokinin octapeptide-induced suppression of feeding.
Pharmacology, biochemistry, and behavior 1984;21(3):339-44.
1984: Kádár T; Pesti A; Penke B; Telegdy G
Inhibition of seizures induced by picrotoxin and electroshock by cholecystokinin octapeptides and their fragments in rats after intracerebroventricular administration.
Neuropharmacology 1984;23(8):955-61.
1984: Telegdy G; Kádár T; Kovács K; Penke B
The inhibition of tail-pinch-induced food intake by cholecystokinin octapeptides and their fragments.
Life sciences 1984;35(2):163-70.
1984: Kádár T; Penke B; Kovács K; Telegdy G
The effects of sulfated and nonsulfated cholecystokinin octapeptides on electroconvulsive shock-induced retrograde amnesia after intracerebroventricular administration in rats.
Neuropeptides 1984;4(2):127-35.
1983: Kádár T; Pesti A; Penke B; Tóth G; Zarándi M; Telegdy G
Structure-activity and dose-effect relationships of the antagonism of picrotoxin-induced seizures by cholecystokinin, fragments and analogues of cholecystokinin in mice.
Neuropharmacology 1983;22(10):1223-9.
1981: Fekete M; Várszegi M; Kádár T; Penke B; Kovács K; Telegdy G
Effect of cholecystokinin octapeptide sulphate ester on brain monoamines in the rat.
Acta physiologica Academiae Scientiarum Hungaricae 1981;57(1):37-46.
1981: Fekete M; Kádár T; Penke B; Kovács K; Telegdy G
Influence of cholecystokinin octapeptide sulfate ester on brain monoamine metabolism in rats.
Journal of neural transmission 1981;50(2-4):81-8.

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