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Botond Penke

Research Profile

Chemicals & Drugs

Living Beings

Disorders

Alzheimer's Disease

Genes & Molecular Sequences

Amino Acid Sequences

Anatomy

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Injections, Intraventricular

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Publications

TOP 3
István Földi; Róbert Berkecz; Zsolt Datki; Emese Mózes; Botond Penke; Zoltán Szabó; Anikó M Tóth; Tamás Janáky
Proteome-wide study of endoplasmic reticulum stress induced by thapsigargin in N2a neuroblastoma cells.
Botond Penke; Mária Szűcs; Anikó M Tóth; István Földi; Tamás Janáky
Intraneuronal β-amyloid and its interactions with proteins and subcellular organelles.
Tamás Huber; Lívia Fülöp; László Grama; Csaba Hetényi; Botond Penke; Gusztáv Schay; Miklós S Z Kellermayer
Conformational dynamics of titin PEVK explored with FRET spectroscopy.

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All Publications

2013: István Földi; Róbert Berkecz; Zsolt Datki; Emese Mózes; Botond Penke; Zoltán Szabó; Anikó M Tóth; Tamás Janáky
Proteome-wide study of endoplasmic reticulum stress induced by thapsigargin in N2a neuroblastoma cells.
Neurochemistry international 2013;62(1):58-69.
2012: Botond Penke; Mária Szűcs; Anikó M Tóth; István Földi; Tamás Janáky
Intraneuronal β-amyloid and its interactions with proteins and subcellular organelles.
Electrophoresis 2012;33(24):3608-16.
2012: Tamás Huber; Lívia Fülöp; László Grama; Csaba Hetényi; Botond Penke; Gusztáv Schay; Miklós S Z Kellermayer
Conformational dynamics of titin PEVK explored with FRET spectroscopy.
Biophysical journal 2012;103(7):1480-9.
2012: Csaba Somlai; Laia Tolosa; Gábor K Tóth; Estela Correche; György Dombi; Maria José Gomez Lechon; Monica Olivella; Botond Penke; Ricardo D Enriz
Synthesis and cytotoxic activity of 4-N-carboxybutyl-5-fluorocytosyl-Arg-Gln-Trp-Arg-Arg-Trp-Trp-Gln-Arg-NH₂.
Bioorganic & medicinal chemistry letters 2012;22(13):4233-7.
2012: Emese Mozes; Botond Penke; Aniko Posa; Akos Hunya; Zsolt Datki
A novel method for the rapid determination of beta-amyloid toxicity on acute hippocampal slices using MTT and LDH assays.
Brain research bulletin 2012;87(6):521-5.
2012: Shirong Liu; Yang Liu; Michael D Menger; Botond Penke; Claudia E Rübe; Jochen Walter; Lisa Wolf; Wenlin Hao; Tobias Hartmann; Michael T Heneka; Amanda J Kiliaan; Klaus Fassbender
TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(3):1098-107.
2012: Katalin A Kékesi; Katalin F Medzihradszky; Miklós Palkovits; Botond Penke; Attila Simor; Eva Mónika Szegő; Zsuzsanna Darula; Péter Gulyássy; Eva Hunyadi-Gulyás; Gábor Juhász; András Czurkó
Altered functional protein networks in the prefrontal cortex and amygdala of victims of suicide.
PloS one 2012;7(12):e50532.
2012: Nikolett Lénárt; Botond Penke; Viktor Szegedi; Melinda E Tóth; Erika Bereczki; János Horváth; Gábor Juhász; Aniko Kasztner; Miklós Sántha
Increased tau phosphorylation and impaired presynaptic function in hypertriglyceridemic ApoB-100 transgenic mice.
PloS one 2012;7(9):e46007.
2012: Balázs Barkóczi; Gábor Juhász; Botond Penke; Petra Vertes; Imre Vörös; Robert G Averkin; Viktor Szegedi
GluA1 phosphorylation alters evoked firing pattern in vivo.
Neural plasticity 2012;2012():286215.
2011: Viktor Szegedi; Xiaoqun Zhang; Hongshi Qi; Michael Spedding; Per Svenningsson; Balázs Barkóczi; Gábor Juhász; Gábor Kapus; Alexandra Madeira; Botond Penke
Tianeptine potentiates AMPA receptors by activating CaMKII and PKA via the p38, p42/44 MAPK and JNK pathways.
Neurochemistry international 2011;59(8):1109-22.
2011: Emese Mozes; Botond Penke; Aniko Toth; Ferhan Ayaydin; Akos Hunya; Zsolt Datki
A novel application of the fluorescent dye bis-ANS for labeling neurons in acute brain slices.
Brain research bulletin 2011;86(3-4):217-21.
2011: Judit Oláh; Ferenc Orosz; Zsolt Bozsó; Emma Hlavanda; István Horváth; János Kovács; Anna Magyar; Botond Penke; Dóra Simon; Orsolya Vincze; Dezsõ Virók; Mária Szũcs; Natália Tõkési; Judit Ovádi
Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein.
The Journal of biological chemistry 2011;286(39):34088-100.
2011: Gábor Janzsó; Ferenc Bogár; Liza Hudoba; Botond Penke; Gábor Rákhely; Balázs Leitgeb
Exploring and characterizing the folding processes of Lys- and Arg-containing Ala-based peptides: a molecular dynamics study.
Computational biology and chemistry 2011;35(4):240-50.
2011: Gábor Juhász; István Földi; Botond Penke
Systems biology of Alzheimer's disease: how diverse molecular changes result in memory impairment in AD.
Neurochemistry international 2011;58(7):739-50.
2011: István Földi; Géza Müller; Botond Penke; Tamás Janáky
Characterisation of the variation of mouse brain proteome by two-dimensional electrophoresis.
Journal of proteomics 2011;74(6):894-901.
2011: Unige Murvai; Katalin Soós; Botond Penke; Miklós S Z Kellermayer
Effect of the beta-sheet-breaker peptide LPFFD on oriented network of amyloid β25-35 fibrils.
Journal of molecular recognition : JMR 2011;24(3):453-60.
2011: István Földi; Zsolt L Datki; Zoltán Szabó; Zsolt Bozsó; Botond Penke; Tamás Janáky
Proteomic study of the toxic effect of oligomeric Aβ1-42 in situ prepared from 'iso-Aβ1-42'.
Journal of neurochemistry 2011;117(4):691-702.
2011: Marcus Otto Walter Grimm; Johanna Kuchenbecker; Sven Grösgen; Verena K Burg; Benjamin Hundsdörfer; Tatjana L Rothhaar; Petra Friess; m de wilde; Laus M Broersen; Botond Penke; Mária Péter; László Vígh; Heike S Grimm; Tobias Hartmann
Docosahexaenoic acid reduces amyloid beta production via multiple pleiotropic mechanisms.
The Journal of biological chemistry 2011;286(16):14028-39.
2011: Dezso P Virok; Dóra Simon; Zsolt Bozsó; Róbert Rajkó; Zsolt Datki; Éva Bálint; Viktor Szegedi; Tamás Janáky; Botond Penke; Lívia Fülöp
Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation.
Journal of proteome research 2011;10(4):1538-47.
2011: m de wilde; Patrick J G H Kamphuis; Almar A M Kuipers; Botond Penke; Eline M Van der Beek; Laus M Broersen
Neuroprotective effects of a specific multi-nutrient intervention against Aβ42-induced toxicity in rats.
Journal of Alzheimer's disease : JAD 2011;27(2):327-39.
2011: Dezso P Virok; Zoltán Kis; Viktor Szegedi; Gábor Juhász; Agnes Zvara; Géza Müller; György Lévay; László G Hársing; Róbert Rajkó; Botond Penke; Zoltán Janka; Tamás Janáky; László G Puskás
Functional changes in transcriptomes of the prefrontal cortex and hippocampus in a mouse model of anxiety.
Pharmacological reports : PR 2011;63(2):348-61.
2011: Wenlin Hao; Yang Liu; Shirong Liu; Silke Walter; Marcus Otto Walter Grimm; Amanda J Kiliaan; Botond Penke; Tobias Hartmann; Claudia E Rübe; Michael D Menger; Klaus Fassbender
Myeloid differentiation factor 88-deficient bone marrow cells improve Alzheimer's disease-related symptoms and pathology.
Brain : a journal of neurology 2011;134(Pt 1):278-92.
2011: Francisco M Garibotto; Adriana D Garro; Ana M Rodríguez; Marcela Raimondi; Susana Zacchino; András Perczel; Csaba Somlai; Botond Penke; Ricardo D Enriz
Penetratin analogues acting as antifungal agents.
European journal of medicinal chemistry 2011;46(1):370-7.
2011: Eva M Szego; Attila Csorba; Tamás Janáky; Katalin A Kékesi; István M Abrahám; Gábor M Mórotz; Botond Penke; Miklós Palkovits; Unige Murvai; Miklós S Z Kellermayer; József Kardos; Gábor D Juhász
Effects of estrogen on beta-amyloid-induced cholinergic cell death in the nucleus basalis magnocellularis.
Neuroendocrinology 2011;93(2):90-105.
2010: A Majzik; Lívia Fülöp; E Csapó; Ferenc Bogár; Tamás A Martinek; Botond Penke; G Bíró; Imre Dékány
Functionalization of gold nanoparticles with amino acid, beta-amyloid peptides and fragment.
Colloids and surfaces. B, Biointerfaces 2010;81(1):235-41.
2010: Gergely Orbán; Katalin Völgyi; Gábor Juhász; Botond Penke; Katalin A Kékesi; József Kardos; András Czurkó
Different electrophysiological actions of 24- and 72-hour aggregated amyloid-beta oligomers on hippocampal field population spike in both anesthetized and awake rats.
Brain research 2010;1354():227-35.
2010: Mónica S Olivella; Ana M Rodríguez; Susana Zacchino; Csaba Somlai; Botond Penke; Victor Farkas; András Perczel; Ricardo D Enriz
New antifungal peptides. Synthesis, bioassays and initial structure prediction by CD spectroscopy.
Bioorganic & medicinal chemistry letters 2010;20(16):4808-11.
2010: Eszter Sipos; Anita Kurunczi; András Fehér; Zsuzsa Penke-Verdier; Lívia Fülöp; Agnes Kasza; János Horváth; Sándor Horvát; Szilvia Veszelka; Gábor Balogh; Levente Kürti; István Eros; Piroska Szabó-Révész; Arpád Párducz; Botond Penke; Mária A Deli
Intranasal delivery of human beta-amyloid peptide in rats: effective brain targeting.
Cellular and molecular neurobiology 2010;30(3):405-13.
2010: Szabina Szücs; Magdolna Pákáski; Agnes Domokos; János Kálmán; Sára Kálmán; Dénes Garab; Botond Penke; Gyula Szabó; Zoltán Janka; János Kálmán
[The effects of duloxetine on beta-actin stress response in rat brain].
Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakológiai Egyesület lapja = official journal of the Hungarian Association of Psychopharmacology 2010;12(1):301-7.
2010: Zsolt Bozso; Botond Penke; Dora Simon; Ilona Laczkó; Gábor Juhász; Viktor Szegedi; Agnes Kasza; Katalin Soós; Anasztázia Hetényi; Edit Wéber; Hajnalka Tóháti; Mária Csete; Márta Zarándi; Lívia Fülöp
Controlled in situ preparation of A beta(1-42) oligomers from the isopeptide "iso-A beta(1-42)", physicochemical and biological characterization.
Peptides 2010;31(2):248-56.
2010: Mária A Deli; Szilvia Veszelka; Boglárka Csiszár; Andrea Tóth; Agnes Kittel; Mária Csete; Aron Sipos; Anikó Szalai; Lívia Fülöp; Botond Penke; Csongor S Abrahám; Masami Niwa
Protection of the blood-brain barrier by pentosan against amyloid-β-induced toxicity.
Journal of Alzheimer's disease : JAD 2010;22(3):777-94.
2010: Gábor J Uhász; Balázs Barkóczi; Gabriella Vass; Zsolt Datki; Akos Hunya; Lívia Fülöp; Dénes Budai; Botond Penke; Viktor Szegedi
Fibrillar Abeta (1-42) enhances NMDA receptor sensitivity via the integrin signaling pathway.
Journal of Alzheimer's disease : JAD 2010;19(3):1055-67.
2010: Ivica Granic; Marcelo F Masman; Cornelis Kees Mulder; Ingrid M Nijholt; Pieter J W Naude; Ammerins de Haan; Emöke Borbély; Botond Penke; Paul G M Luiten; Ulrich L M Eisel
LPYFDa neutralizes amyloid-beta-induced memory impairment and toxicity.
Journal of Alzheimer's disease : JAD 2010;19(3):991-1005.
2010: Francisco M Garibotto; Adriana D Garro; Marcelo F Masman; Ana M Rodríguez; Paul G M Luiten; Marcela Raimondi; Susana Zacchino; Csaba Somlai; Botond Penke; Ricardo D Enriz
New small-size peptides possessing antifungal activity.
Bioorganic & medicinal chemistry 2010;18(1):158-67.
2009: Marcelo F Masman; Ulrich L M Eisel; Imre G Csizmadia; Botond Penke; Ricardo D Enriz; Siewert J Marrink; Paul G M Luiten
In silico study of full-length amyloid beta 1-42 tri- and penta-oligomers in solution.
The journal of physical chemistry. B 2009;113(34):11710-9.
2009: József Huszár; Zoltán Timár; Ferenc Bogár; Botond Penke; Róbert Kiss; Krisztina Katalin Szalai; Eva Schmidt; Andrea Papp; György Keseru
Aspartic acid scaffold in bradykinin B1 antagonists.
Journal of peptide science : an official publication of the European Peptide Society 2009;15(6):423-34.
2009: Rimante Minkeviciene; Sylvain Rheims; Marton B Dobszay; Misha Zilberter; Jarmo Hartikainen; Lívia Fülöp; Botond Penke; Yuri Zilberter; Tibor Harkany; Asla Pitkänen; Heikki Tanila
Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(11):3453-62.
2009: Gábor Juhász; Arpád Márki; Gabriella Vass; Lívia Fülöp; Dénes Budai; Botond Penke; György Falkay; Viktor Szegedi
An intraperitoneally administered pentapeptide protects against Abeta (1-42) induced neuronal excitation in vivo.
Journal of Alzheimer's disease : JAD 2009;16(1):189-96.
2009: Marcelo F Masman; Ana M Rodríguez; Marcela Raimondi; Susana Zacchino; Paul G M Luiten; Csaba Somlai; Tamas Kortvelyesi; Botond Penke; Ricardo D Enriz
Penetratin and derivatives acting as antifungal agents.
European journal of medicinal chemistry 2009;44(1):212-28.
2008: Gábor Juhász; Gabriella Vass; Zsolt Bozsó; Dénes Budai; Botond Penke; Viktor Szegedi
Integrin activation modulates NMDA and AMPA receptor function of CA1 cells in a dose-related fashion in vivo.
Brain research 2008;1233():20-6.
2008: Arpád Karsai; Unige Murvai; Katalin Soós; Botond Penke; Miklós Kellermayer
Oriented epitaxial growth of amyloid fibrils of the N27C mutant beta 25-35 peptide.
European biophysics journal : EBJ 2008;37(7):1133-7.
2008: Ingrid M Nijholt; Anghelus Ostroveanu; Wouter A Scheper; Botond Penke; Paul G M Luiten; Eddy A Van der Zee; Ulrich L M Eisel
Inhibition of PKA anchoring to A-kinase anchoring proteins impairs consolidation and facilitates extinction of contextual fear memories.
Neurobiology of learning and memory 2008;90(1):223-9.
2008: József Huszár; Zoltán Timár; Krisztina Katalin Szalai; György Keseru; Ferenc FüLöp; Botond Penke
Novel bradykinin-1 antagonists containing a (1,2,3,4-tetrahydro-isoquinolin-1-yl)acetic acid scaffold.
European journal of medicinal chemistry 2008;43(7):1552-8.
2008: Ilona Laczkó; Elemér Vass; Katalin Soós; Livia Fülöp; Márta Zarándi; Botond Penke
Aggregation of Abeta(1-42) in the presence of short peptides: conformational studies.
Journal of peptide science : an official publication of the European Peptide Society 2008;14(6):731-41.
2008: Yann Verdier; István Földi; Nicolas Sergeant; Lívia Fülöp; Zsuzsa Penke-Verdier; Tamás Janáky; Mária Szücs; Botond Penke
Characterization of the interaction between Abeta 1-42 and glyceraldehyde phosphodehydrogenase.
Journal of peptide science : an official publication of the European Peptide Society 2008;14(6):755-62.
2008: Marcelo F Masman; Csaba Somlai; Francisco M Garibotto; Ana M Rodríguez; Agustina de la Iglesia; Susana Zacchino; Botond Penke; Ricardo D Enriz
Structure-antifungal activity relationship of His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 and analogues.
Bioorganic & medicinal chemistry 2008;16(8):4347-58.
2008: Akos Hunya; István Földi; Viktor Szegedi; Katalin Soós; Márta Zarándi; Antal Szabó; Dénes Zádori; Botond Penke; Zsolt Datki
Differences between normal and alpha-synuclein overexpressing SH-SY5Y neuroblastoma cells after Abeta(1-42) and NAC treatment.
Brain research bulletin 2008;75(5):648-54.
2008: Anasztázia Hetényi; Lívia Fülöp; Tamás A Martinek; Edit Wéber; Katalin Soós; Botond Penke
Ligand-induced flocculation of neurotoxic fibrillar Abeta(1-42) by noncovalent crosslinking.
Chembiochem : a European journal of chemical biology 2008;9(5):748-57.
2008: Miklós Kellermayer; Arpád Karsai; Margit Benke; Katalin Soós; Botond Penke
Stepwise dynamics of epitaxially growing single amyloid fibrils.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(1):141-4.
2007: Dénes Zádori; Zsolt Datki; Botond Penke
[The role of chronic brain hypoperfusion in the pathogenesis of Alzheimer's disease--facts and hypotheses].
Ideggyógyászati szemle 2007;60(11-12):428-37.
2007: Balázs Leitgeb; Adám Kerényi; Ferenc Bogár; Gábor Paragi; Botond Penke; Gábor Rákhely
Studying the structural properties of polyalanine and polyglutamine peptides.
Journal of molecular modeling 2007;13(11):1141-50.
2007: Anita Annaházi; Eva Mracskó; Zoltán Süle; Eszter Karg; Botond Penke; Ferenc Bari; Eszter Farkas
Pre-treatment and post-treatment with alpha-tocopherol attenuates hippocampal neuronal damage in experimental cerebral hypoperfusion.
European journal of pharmacology 2007;571(2-3):120-8.
2007: Zsolt Datki; Akos Hunya; Botond Penke
A novel and simple fluorescence method for the measurement of presynaptic vesicular zinc release in acute hippocampal slices with a fluorescence plate reader.
Brain research bulletin 2007;74(1-3):183-7.
2007: E Sipos; A Kurunczi; A Kasza; J Horváth; Klára Felszeghy; S Laroche; József Toldi; Arpád Párducz; Botond Penke; Zsuzsa Penke-Verdier
Beta-amyloid pathology in the entorhinal cortex of rats induces memory deficits: implications for Alzheimer's disease.
Neuroscience 2007;147(1):28-36.
2007: Zsuzsanna Hartai; Peter Klivenyi; Tamas Janaky; Botond Penke; László Dux; Laszlo Vecsei
Peripheral kynurenine metabolism in focal dystonia.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2007;3(3):285-8.
2007: Joseph Molnár; Helga Engi; Yvette Mándi; Csaba Somlai; Botond Penke; András Szabó; Antal Orosz
Effects of nontoxic heat shock protein 90 inhibitor peptide derivatives on reversal of MDR of tumor cells.
In vivo (Athens, Greece) 2007;21(2):429-33.
2007: Márta Zarándi; Katalin Soós; Lívia Fülöp; Zsolt Bozsó; Zsolt Datki; Gábor K Tóth; Botond Penke
Synthesis of Abeta[1-42] and its derivatives with improved efficiency.
Journal of peptide science : an official publication of the European Peptide Society 2007;13(2):94-9.
2007: Silke Walter; Maryse Letiembre; Yang Liu; Holger Heine; Botond Penke; Wenlin Hao; Barbara Bode; Nicole Manietta; Jessica Walter; Walter Schulz-Schuffer; Klaus Fassbender
Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;20(6):947-56.
2007: Zsuzsanna Hartai; Anna Juhász; Agnes Rimanóczy; Tamás Janáky; Teodóra Donkó; László Dux; Botond Penke; Gábor K Tóth; Zoltán Janka; János Kálmán
Decreased serum and red blood cell kynurenic acid levels in Alzheimer's disease.
Neurochemistry international 2007;50(2):308-13.
2006: Marcelo F Masman; Ana M Rodríguez; Laura Svetaz; Susana Zacchino; Csaba Somlai; Imre G Csizmadia; Botond Penke; Ricardo D Enriz
Synthesis and conformational analysis of His-Phe-Arg-Trp-NH2 and analogues with antifungal properties.
Bioorganic & medicinal chemistry 2006;14(22):7604-14.
2006: Arpád Karsai; Zsolt Mártonfalvi; Attila Nagy; László Grama; Botond Penke; Miklós Kellermayer
Mechanical manipulation of Alzheimer's amyloid beta1-42 fibrils.
Journal of structural biology 2006;155(2):316-26.
2006: Viktor Szegedi; Gábor Juhász; Eva Rózsa; Gabriella Juhász-Vedres; Zsolt Datki; Lívia Fülöp; Zsolt Bozsó; Andrea Lakatos; Ilona Laczkó; Tamás Farkas; Zsolt Kis; Géza Tóth; Katalin Soós; Márta Zarándi; Dénes Budai; József Toldi; Botond Penke
Endomorphin-2, an endogenous tetrapeptide, protects against Abeta1-42 in vitro and in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(8):1191-3.
2006: Tamás Letoha; Erzsébet Kusz; Gábor Pápai; Annamária Szabolcs; József Kaszaki; Ilona Varga; Tamás Takács; Botond Penke; Erno Duda
In vitro and in vivo nuclear factor-kappaB inhibitory effects of the cell-penetrating penetratin peptide.
Molecular pharmacology 2006;69(6):2027-36.
2006: Marianna Zana; Anna Juhász; Agnes Rimanóczy; Annamária Bjelik; Eszter Baltás; Imre Ocsovszki; Krisztina Boda; Botond Penke; Attila Dobozy; Lajos Kemeny; Zoltán Janka; János Kálmán
Alzheimer's lymphocytes are resistant to ultraviolet B-induced apoptosis.
Neurobiology of aging 2006;27(6):831-4.
2006: Jacqueline M S Law; Milan Szori; Robert Izsak; Botond Penke; Imre G Csizmadia; Béla Viskolcz
Folded and unfolded conformations of the omega-3 polyunsaturated fatty acid family: ch(3)ch(2)[ch=chch(2)](b)[ch(2)](m)cooh: first principles study.
The journal of physical chemistry. A 2006;110(18):6100-11.
2006: Isaac Shemer; Carl Holmgren; Rogier Min; Livia Fülöp; Misha Zilberter; Kyle M Sousa; Tamás Farkas; Wolfgang Härtig; Botond Penke; Nail Burnashev; Heikki Tanila; Yuri Zilberter; Tibor Harkany
Non-fibrillar beta-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors.
The European journal of neuroscience 2006;23(8):2035-47.
2006: Csaba Hetényi; Gábor Paragi; Uko Maran; Zoltán Timár; Mati Karelson; Botond Penke
Combination of a modified scoring function with two-dimensional descriptors for calculation of binding affinities of bulky, flexible ligands to proteins.
Journal of the American Chemical Society 2006;128(4):1233-9.
2006: János Kálmán; Anna Juhász; Gábor Bogáts; Barna Babik; Agnes Rimanóczy; Zoltán Janka; Botond Penke; Andras Palotas
Elevated levels of inflammatory biomarkers in the cerebrospinal fluid after coronary artery bypass surgery are predictors of cognitive decline.
Neurochemistry international 2006;48(3):177-80.
2006: Antal Orosz; Andrea Szabo; Gabriella Szeman; Tamas Janaky; Csaba Somlai; Botond Penke; Andrea Bodor; András Perczel
Novel nontoxic heat shock protein 90 inhibitors having selective antiproliferative effect.
The international journal of biochemistry & cell biology 2006;38(8):1352-62.
2005: Zsuzsanna Hartai; Peter Klivenyi; Tamas Janaky; Botond Penke; László Dux; Laszlo Vecsei
Kynurenine metabolism in plasma and in red blood cells in Parkinson's disease.
Journal of the neurological sciences 2005;239(1):31-5.
2005: Tamás Letoha; Szilvia Gaál; Csaba Somlai; Zsolt Venkei; Hristos Glavinas; Erzsébet Kusz; Erno Duda; András Czajlik; Ferenc Peták; Botond Penke
Investigation of penetratin peptides. Part 2. In vitro uptake of penetratin and two of its derivatives.
Journal of peptide science : an official publication of the European Peptide Society 2005;11(12):805-11.
2005: Viktor Szegedi; Gábor Juhász; Dénes Budai; Botond Penke
Divergent effects of Abeta1-42 on ionotropic glutamate receptor-mediated responses in CA1 neurons in vivo.
Brain research 2005;1062(1-2):120-6.
2005: Arpád Karsai; Attila Nagy; András Kengyel; Zsolt Mártonfalvi; László Grama; Botond Penke; Miklós Kellermayer
Effect of lysine-28 side-chain acetylation on the nanomechanical behavior of alzheimer amyloid beta25-35 fibrils.
Journal of chemical information and modeling 2005;45(6):1641-6.
2005: Tamás Letoha; Csaba Somlai; Tamás Takács; Annamária Szabolcs; Zoltán Rakonczay; Katalin Jármay; Tamás Szalontai; Ilona Varga; József Kaszaki; Imre Boros; Erno Duda; László Hackler; István Kurucz; Botond Penke
The proteasome inhibitor MG132 protects against acute pancreatitis.
Free radical biology & medicine 2005;39(9):1142-51.
2005: Liliána Fehér; János Kálmán; László G Puskás; Gábor Gyülvészi; Klára Kitajka; Botond Penke; Miklós Palotás; Elena I Samarova; Joseph Molnár; Agnes Zvara; Keyvan Matin; Nikoletta Bódi; Marietta Hugyecz; Magdolna Pákáski; Annamária Bjelik; Anna Juhász; Gábor Bogáts; Zoltán Janka; Andras Palotas
Impact of haloperidol and risperidone on gene expression profile in the rat cortex.
Neurochemistry international 2005;47(4):271-80.
2005: Ferenc Bogár; Zs Szekeres; F Bartha; Botond Penke; János J Ladik
Density functional study of infinite polyserine chains.
Physical chemistry chemical physics : PCCP 2005;7(15):2965-9.
2005: Zsuzsanna Hartai; Peter Klivenyi; Tamas Janaky; Botond Penke; László Dux; Laszlo Vecsei
Kynurenine metabolism in multiple sclerosis.
Acta neurologica Scandinavica 2005;112(2):93-6.
2005: Yann Verdier; Emoke Huszár; Botond Penke; Zsuzsa Penke-Verdier; Gary Woffendin; Michaela Scigelova; Lívia Fülöp; Mária Szucs; Katalin Medzihradszky; Tamás Janáky
Identification of synaptic plasma membrane proteins co-precipitated with fibrillar beta-amyloid peptide.
Journal of neurochemistry 2005;94(3):617-28.
2005: Yang Liu; Silke Walter; Massimiliano Stagi; Dmitry Cherny; Maryse Letiembre; Walter Schulz-Schaeffer; Holger Heine; Botond Penke; Harald Neumann; Klaus Fassbender
LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide.
Brain : a journal of neurology 2005;128(Pt 8):1778-89.
2005: Gregory A Chass; Rei S Mirasol; David H Setiadi; Ting-Hua Tang; Wutharath Chin; Michel Mons; Iliana Dimicoli; Jean-Pierre Dognon; Béla Viskolcz; Sandor Lovas; Botond Penke; Imre G Csizmadia
Characterization of the conformational probability of N-acetyl-phenylalanyl-NH2 by RHF, DFT, and MP2 computation and AIM analyses, confirmed by jet-cooled infrared data.
The journal of physical chemistry. A 2005;109(24):5289-302.
2005: Ferenc Bogár; Balázs Leitgeb; Gábor Paragi; Antal Orosz; Botond Penke
Comparative study of SP[6-11] and its analogs using simulated annealing.
Biopolymers 2005;78(1):35-45.
2005: Viktor Szegedi; Lívia Fülöp; Tamás Farkas; Eva Rózsa; Hermina Robotka; Zsolt Kis; Zsuzsa Penke-Verdier; Szatmár Horváth; Zsolt Molnár; Zsolt Datki; Katalin Soós; József Toldi; Dénes Budai; Márta Zarándi; Botond Penke
Pentapeptides derived from Abeta 1-42 protect neurons from the modulatory effect of Abeta fibrils--an in vitro and in vivo electrophysiological study.
Neurobiology of disease 2005;18(3):499-508.
2005: Michelle A Sahai; Tara A K Kehoe; Joseph C P Koo; David H Setiadi; Gregory A Chass; Béla Viskolcz; Botond Penke; Emil F Pai; Imre G Csizmadia
First principle computational study on the full conformational space of L-proline diamides.
The journal of physical chemistry. A 2005;109(11):2660-79.
2005: Miklós Kellermayer; László Grama; Arpád Karsai; Attila Nagy; Amram Kahn; Zsolt Datki; Botond Penke
Reversible mechanical unzipping of amyloid beta-fibrils.
The Journal of biological chemistry 2005;280(9):8464-70.
2005: Tamás Letoha; Csaba Somlai; Tamas Takacs; Annamária Szabolcs; Katalin Jarmay; Zoltán Rakonczay; Péter Hegyi; Ilona Varga; József Kaszaki; István A Krizbai; Imre Boros; Erno Duda; Erzsébet Kusz; Botond Penke
A nuclear import inhibitory peptide ameliorates the severity of cholecystokinin-induced acute pancreatitis.
World journal of gastroenterology : WJG 2005;11(7):990-9.
2005: Enzo Lain; Botond Penke; André Delacourte; Daniela Gündisch; Hannsjörg Schröder; Brigitte Witter
Effects of Abeta1-42 fibrils and of the tetrapeptide Pr-IIGL on the phosphorylation state of the tau-protein and on the alpha7 nicotinic acetylcholine receptor in vitro.
The European journal of neuroscience 2005;21(4):879-88.
2004: Zsolt Datki; Rita Papp; Dénes Zádori; Katalin Soós; Lívia Fülöp; Anna Juhász; Gábor Laskay; Csaba Hetényi; Erzsébet Mihalik; Márta Zarándi; Botond Penke
In vitro model of neurotoxicity of Abeta 1-42 and neuroprotection by a pentapeptide: irreversible events during the first hour.
Neurobiology of disease 2004;17(3):507-15.
2004: Miklós Palotás; Andras Palotas; László G Puskás; Klára Kitajka; Magdolna Pákáski; Zoltán Janka; Joseph Molnár; Botond Penke; János Kálmán
Gene expression profile analysis of the rat cortex following treatment with imipramine and citalopram.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2004;7(4):401-13.
2004: Lívia Fülöp; Márta Zarándi; Zsolt Datki; Katalin Soós; Botond Penke
Beta-amyloid-derived pentapeptide RIIGLa inhibits Abeta(1-42) aggregation and toxicity.
Biochemical and biophysical research communications 2004;324(1):64-9.
2004: Andras Palotas; László G Puskás; Klára Kitajka; Miklós Palotás; Joseph Molnár; Magdolna Pákáski; Zoltán Janka; Botond Penke; János Kálmán
Altered response to mirtazapine on gene expression profile of lymphocytes from Alzheimer's patients.
European journal of pharmacology 2004;497(3):247-54.
2004: Andras Palotas; László G Puskás; Klára Kitajka; Miklós Palotás; Joseph Molnár; Magdolna Pákáski; Zoltán Janka; Botond Penke; János Kálmán
The effect of citalopram on gene expression profile of Alzheimer lymphocytes.
Neurochemical research 2004;29(8):1563-70.
2004: János Kálmán; Anna Juhász; Zoltán Rakonczay; György Abrahám; Marianna Zana; Krisztina Boda; Tamás Farkas; Botond Penke; Zoltán Janka
Increased serum butyrylcholinesterase activity in type IIb hyperlipidaemic patients.
Life sciences 2004;75(10):1195-204.
2004: Zsolt Molnár; Katalin Soós; Imre Lengyel; Botond Penke; Viktor Szegedi; Dénes Budai
Enhancement of NMDA responses by beta-amyloid peptides in the hippocampus in vivo.
Neuroreport 2004;15(10):1649-52.
2004: Andras Palotas; Botond Penke; Miklós Palotás; Anna Szabo Kenderessy; Lajos Kemeny; E Kis; Gábor Vincze; Zoltán Janka; János Kálmán
Haloperidol attenuates beta-amyloid-induced calcium imbalance in human fibroblasts.
Skin pharmacology and physiology 2004;17(4):195-9.
2004: Zsolt Molnár; P Kovács; Ilona Laczkó; Katalin Soós; Lívia Fülöp; Botond Penke; Imre Lengyel
Enhanced G-protein activation by a mixture of Abeta(25-35), Abeta(1-40/42) and zinc.
Journal of neurochemistry 2004;89(5):1215-23.
2004: Yann Verdier; Márta Zarándi; Botond Penke
Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease.
Journal of peptide science : an official publication of the European Peptide Society 2004;10(5):229-48.
2004: Andras Palotas; Botond Penke; Lajos Kemeny; Zoltán Janka; János Kálmán
A chapter in the unity of variety--calcium is the sole author?
Brain research 2004;1000(1-2):57-9.
2004: János Kálmán; Anna Juhász; Zoltán Janka; Zoltán Rakonczay; György Abrahám; Krisztina Boda; Tamás Farkas; Botond Penke
Serum butyrylcholinesterase activity in hyperlipidaemia.
Atherosclerosis 2004;173(1):145-6.
2004: Yann Verdier; Botond Penke
Binding sites of amyloid beta-peptide in cell plasma membrane and implications for Alzheimer's disease.
Current protein & peptide science 2004;5(1):19-31.
2004: Judit Füvesi; Csaba Somlai; Hajnalka Németh; Hedvig Varga; Zsolt Kis; Tamás Farkas; Norbert Károly; Márton Dobszay; Zsuzsa Penke-Verdier; Botond Penke; László Vécsei; József Toldi
Comparative study on the effects of kynurenic acid and glucosamine-kynurenic acid.
Pharmacology, biochemistry, and behavior 2004;77(1):95-102.
2004: Klaus Fassbender; Silke Walter; Sandra Kühl; Regine Landmann; K Ishii; Thomas Bertsch; Anna K Stalder; Frank Muehlhauser; Yang Liu; Artur J Ulmer; Serge Rivest; Arnd Lentschat; E Gulbins; Mathias Jucker; Matthias Staufenbiel; Katrin Brechtel; J Walter; Gerd Multhaup; Botond Penke; Y Adachi; Tobias Hartmann; Konrad Beyreuther
The LPS receptor (CD14) links innate immunity with Alzheimer's disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):203-5.
2003: Zsolt Datki; Anna Juhász; Márta Gálfi; Katalin Soós; Rita Papp; Dénes Zádori; Botond Penke
Method for measuring neurotoxicity of aggregating polypeptides with the MTT assay on differentiated neuroblastoma cells.
Brain research bulletin 2003;62(3):223-9.
2003: Judit Erchegyi; Botond Penke; Lajos Simon; Scott Michaelson; Sandra Wenger; Beatrice Waser; Renzo Cescato; Jean-Claude Schaer; Jean Claude Reubi; Jean Rivier
Novel sst(4)-selective somatostatin (SRIF) agonists. 2. Analogues with beta-methyl-3-(2-naphthyl)alanine substitutions at position 8.
Journal of medicinal chemistry 2003;46(26):5587-96.
2003: Andras Palotas; Magdolna Pákáski; Miklós Palotás; Marietta Hugyecz; Joseph Molnár; Botond Penke; Zoltán Janka; János Kálmán
Effect of haloperidol and risperidone on amyloid precursor protein levels in vivo.
Brain research bulletin 2003;62(2):93-9.
2003: Tamás Letoha; S Gaál; Csaba Somlai; András Czajlik; András Perczel; Botond Penke
Membrane translocation of penetratin and its derivatives in different cell lines.
Journal of molecular recognition : JMR 2003;16(5):272-9.
2003: Andras Palotas; János Kálmán; Miklós Palotás; Lajos Kemeny; Zoltán Janka; Botond Penke
Long-term exposition of cells to beta-amyloid results in decreased intracellular calcium concentration.
Neurochemistry international 2003;42(7):543-7.
2003: E Högyes; Csaba Nyakas; Amanda J Kiliaan; T Farkas; Botond Penke; Paul G M Luiten
Neuroprotective effect of developmental docosahexaenoic acid supplement against excitotoxic brain damage in infant rats.
Neuroscience 2003;119(4):999-1012.
2003: Ibolya G Farkas; Andrea Czigner; Eszter Farkas; Endre Dobó; Katalin Soós; Botond Penke; Valéria Endrész; András Mihály
Beta-amyloid peptide-induced blood-brain barrier disruption facilitates T-cell entry into the rat brain.
Acta histochemica 2003;105(2):115-25.
2002: Andras Palotas; János Kálmán; Miklós Palotás; Keyvan Matin; Károly Szentpáli; Attila Paszt; Zoltán Janka; Botond Penke
Whole blood samples from Alzheimer patients and control donors demonstrate fluorimetric differences.
Neurochemical research 2002;27(12):1589-91.
2002: Peter P Mager; Botond Penke; Regina Walter; Tibor Harkany; Wolfgang Härtignny
Pathological peptide folding in Alzheimer's disease and other conformational disorders.
Current medicinal chemistry 2002;9(19):1763-80.
2002: Andras Palotas; János Kálmán; Miklós Palotás; Anna Juhász; Zoltán Janka; Botond Penke
Fibroblasts and lymphocytes from Alzheimer patients are resistant to beta-amyloid-induced increase in the intracellular calcium concentration.
Progress in neuro-psychopharmacology & biological psychiatry 2002;26(5):971-4.
2002: Andras Palotas; János Kálmán; Miklós Palotás; Anna Juhász; Zoltán Janka; Botond Penke
Beta-amyloid-induced increase in the resting intracellular calcium concentration gives support to tell Alzheimer lymphocytes from control ones.
Brain research bulletin 2002;58(2):203-5.
2002: Andras Palotas; János Kálmán; Gábor Laskay; Anna Juhász; Zoltán Janka; Botond Penke
[Change of fibroblast calcium levels caused by beta-amyloid peptide in Alzheimer disease].
Ideggyógyászati szemle 2002;55(5-6):164-7.
2002: Tibor Harkany; Csaba Varga; Jens Grosche; Jan Mulder; Paul G M Luiten; Tibor Hortobágyi; Botond Penke; Wolfgang Härtig
Distinct subsets of nucleus basalis neurons exhibit similar sensitivity to excitotoxicity.
Neuroreport 2002;13(6):767-72.
2002: Csaba Hetényi; Tamás Körtvélyesi; Botond Penke
Mapping of possible binding sequences of two beta-sheet breaker peptides on beta amyloid peptide of Alzheimer's disease.
Bioorganic & medicinal chemistry 2002;10(5):1587-93.
2002: Csaba Hetényi; Zoltán Szabó; Eva Klement; Zsolt Datki; Tamás Körtvélyesi; Márta Zarándi; Botond Penke
Pentapeptide amides interfere with the aggregation of beta-amyloid peptide of Alzheimer's disease.
Biochemical and biophysical research communications 2002;292(4):931-6.
2002: András Czajlik; Eszter Meskó; Botond Penke; András Perczel
Investigation of penetratin peptides. Part 1. The environment dependent conformational properties of penetratin and two of its derivatives.
Journal of peptide science : an official publication of the European Peptide Society 2002;8(4):151-71.
2002: Wolfgang Härtig; Andreas Bauer; Kurt Brauer; Jens Grosche; Tibor Hortobágyi; Botond Penke; Reinhard Schliebs; Tibor Harkany
Functional recovery of cholinergic basal forebrain neurons under disease conditions: old problems, new solutions?
Reviews in the neurosciences 2002;13(2):95-165.
2001: Zsófia Lázár; Anaid Shahbazian; Rita Benkó; Gábor Tóth; Botond Penke; Lorand Barthó; Peter Holzer
PACAP-(6-38) inhibits the effects of vasoactive intestinal polypeptide, but not PACAP, on the small intestinal circular muscle.
European journal of pharmacology 2001;431(2):259-64.
2001: Lívia Fülöp; Botond Penke; Márta Zarándi
Synthesis and fluorescent labeling of beta-amyloid peptides.
Journal of peptide science : an official publication of the European Peptide Society 2001;7(8):397-401.
2001: Tibor Harkany; S O'Mahony; Jan N Keijser; J P Kelly; C Kónya; Z A Borostyánkoi; Tamás J Görcs; Márta Zarándi; Botond Penke; Brian E Leonard; Paul G M Luiten
Beta-amyloid(1-42)-induced cholinergic lesions in rat nucleus basalis bidirectionally modulate serotonergic innervation of the basal forebrain and cerebral cortex.
Neurobiology of disease 2001;8(4):667-78.
2001: Andras Palotas; János Kálmán; Gábor Laskay; Anna Juhász; Zoltán Janka; Botond Penke
Comparative studies on [Ca2+]i-level of fibroblasts from Alzheimer patients and control individuals.
Neurochemical research 2001;26(7):817-20.
2001: Z Kupihár; Z Schmél; Zoltán Kele; Botond Penke; Lajos Kovács
Synthesis and application of a novel, crystalline phosphoramidite monomer with thiol terminus, suitable for the synthesis of DNA conjugates.
Bioorganic & medicinal chemistry 2001;9(5):1241-7.
2000: Tibor Harkany; István M Abrahám; W Timmerman; Gábor Laskay; B Tóth; Mária Sasvári; C Kónya; J B Sebens; J Korf; Csaba Nyakas; Márta Zarándi; Katalin Soós; Botond Penke; Paul G M Luiten
beta-amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis.
The European journal of neuroscience 2000;12(8):2735-45.
2000: K Ishii; F Muelhauser; U Liebl; M Picard; Sandra Kühl; Botond Penke; Thomas A Bayer; M Wiessler; Michael Hennerici; Konrad Beyreuther; Tobias Hartmann; Klaus Fassbender
Subacute NO generation induced by Alzheimer's beta-amyloid in the living brain: reversal by inhibition of the inducible NO synthase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(11):1485-9.
2000: István M Abrahám; Tibor Harkany; Katalin Horváth; Alexa H Veenema; Botond Penke; Csaba Nyakas; Paul G M Luiten
Chronic corticosterone administration dose-dependently modulates Abeta(1-42)- and NMDA-induced neurodegeneration in rat magnocellular nucleus basalis.
Journal of neuroendocrinology 2000;12(6):486-94.
2000: László Lénárd; Zsófia Lázár; Rita Benkó; Réka Szigeti; Z Báthori; Gábor K Tóth; Botond Penke; Lorand Barthó
Inhibitory effect of PACAP(6-38) on relaxations induced by PACAP, VIP and non-adrenergic, non-cholinergic nerve stimulation in the guinea-pig taenia caeci.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(5):492-7.
2000: Tibor Harkany; Botond Penke; Paul G M Luiten
beta-Amyloid excitotoxicity in rat magnocellular nucleus basalis. Effect of cortical deafferentation on cerebral blood flow regulation and implications for Alzheimer's disease.
Annals of the New York Academy of Sciences 2000;903():374-86.
2000: Lorand Barthó; Zsófia Lázár; László Lénárd; Rita Benkó; Gábor Tóth; Botond Penke; János Szolcsányi; Carlo A Maggi
Evidence for the involvement of ATP, but not of VIP/PACAP or nitric oxide, in the excitatory effect of capsaicin in the small intestine.
European journal of pharmacology 2000;392(3):183-8.
2000: Péter Kása; Henrietta Papp; I Kovacs; M Forgon; Botond Penke; Haruyasu Yamaguchi
Human amyloid-beta1-42 applied in vivo inhibits the fast axonal transport of proteins in the sciatic nerve of rat.
Neuroscience letters 2000;278(1-2):117-9.
2000: Tibor Harkany; István M Abrahám; C Kónya; Csaba Nyakas; Márta Zarándi; Botond Penke; Paul G M Luiten
Mechanisms of beta-amyloid neurotoxicity: perspectives of pharmacotherapy.
Reviews in the neurosciences 2000;11(4):329-82.
1999: Zoltán Szabó; Eva Klement; Krisztina Jost; Márta Zarándi; Katalin Soós; Botond Penke
An FT-IR study of the beta-amyloid conformation: standardization of aggregation grade.
Biochemical and biophysical research communications 1999;265(2):297-300.
1999: T Harkany; Tibor Hortobágyi; Mária Sasvári; C Kónya; Botond Penke; P G Luiten; Csaba Nyakas
Neuroprotective approaches in experimental models of beta-amyloid neurotoxicity: relevance to Alzheimer's disease.
Progress in neuro-psychopharmacology & biological psychiatry 1999;23(6):963-1008.
1999: Tibor Harkany; István M Abrahám; Gábor Laskay; W Timmerman; Krisztina Jost; Márta Zarándi; Botond Penke; Csaba Nyakas; Paul G M Luiten
Propionyl-IIGL tetrapeptide antagonizes beta-amyloid excitotoxicity in rat nucleus basalis.
Neuroreport 1999;10(8):1693-8.
1999: Tibor Harkany; Jan Mulder; Mária Sasvári; István M Abrahám; C Kónya; Márta Zarándi; Botond Penke; Paul G M Luiten; Csaba Nyakas
N-Methyl-D-aspartate receptor antagonist MK-801 and radical scavengers protect cholinergic nucleus basalis neurons against beta-amyloid neurotoxicity.
Neurobiology of disease 1999;6(2):109-21.
1999: Gábor Laskay; Márta Zarándi; Krisztina Jost; Botond Penke; E Bálint; Imre Ocsovszki; M Tarcsa; S Várszegi; Karoly Gulya
beta-Amyloid[1-40]-induced early hyperpolarization in M26-1F cells, an immortalized rat striatal cell line.
Neurobiology (Budapest, Hungary) 1999;7(4):431-6.
1999: Annamária Kovács; Gyula Telegdy; Gábor Tóth; Botond Penke
Neurotransmitter-mediated open-field behavioral action of CGRP.
Life sciences 1999;64(9):733-40.
1998: Gábor Jancsó; Ferenc Domoki; Péter Sántha; Jozsef Varga; J Fischer; K Orosz; Botond Penke; A Becskei; Mária Dux; L Tóth
Beta-amyloid (1-42) peptide impairs blood-brain barrier function after intracarotid infusion in rats.
Neuroscience letters 1998;253(2):139-41.
1998: Magdolna Pakaski; Zoltán Farkas; Péter Kása; M Forgon; Henrietta Papp; M Zarandi; Botond Penke; P Kasa
Vulnerability of small GABAergic neurons to human beta-amyloid pentapeptide.
Brain research 1998;796(1-2):239-46.
1998: Laszlo Torday; János Pataricza; G E Balogh; Márta Zarándi; Botond Penke; Julius Gy Papp
Endothelium-dependent vasorelaxant and anti-aggregatory effect and mechanism of action of some antifibrinogen RGD (Arg-Gly-Asp-containing) peptides.
The Journal of pharmacy and pharmacology 1998;50(6):667-71.
1998: János Pataricza; Botond Penke; G E Balogh; Julius Gy Papp
Polarographic detection of nitric oxide released from cardiovascular compounds in aqueous solutions.
Journal of pharmacological and toxicological methods 1998;39(2):91-5.
1998: Tibor Harkany; S O'Mahony; J P Kelly; Katalin Soós; I Törõ; Botond Penke; Paul G M Luiten; Csaba Nyakas; K Gulya; Brian E Leonard
Beta-amyloid(Phe(SO3H)24)25-35 in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cortical cholinergic innervation.
Behavioural brain research 1998;90(2):133-45.
1998: Péter Kása; Botond Penke; Magdolna Pakaski
Amyloid beta-peptide treatment induces a redistribution of acetylcholinesterase within the enzyme-containing neurons in in vitro tissue cultures.
Neurobiology (Budapest, Hungary) 1998;6(3):369-71.
1998: M Forgon; Zoltán Farkas; Karoly Gulya; Magdolna Pakaski; Botond Penke; Péter Kása
Amyloid beta-peptide and its fragments induce acetylcholine release in in vitro basal forebrain tissue slices of rat brain, but do not affect the choline uptake.
Neurobiology (Budapest, Hungary) 1998;6(3):359-61.
1998: S O'Mahony; Tibor Harkany; A A Rensink; István M Abrahám; GI de Jong; Jozsef Varga; Márta Zarándi; Botond Penke; Csaba Nyakas; Paul G M Luiten; Brian E Leonard
Beta-amyloid-induced cholinergic denervation correlates with enhanced nitric oxide synthase activity in rat cerebral cortex: reversal by NMDA receptor blockade.
Brain research bulletin 1998;45(4):405-11.
1997: Gábor Laskay; Márta Zarándi; Jozsef Varga; Krisztina Jost; A Fónagy; C Torday; L Latzkovits; Botond Penke
A putative tetrapeptide antagonist prevents beta-amyloid-induced long-term elevation of [Ca2+]i in rat astrocytes.
Biochemical and biophysical research communications 1997;235(3):479-81.
1997: Edit Biró; Botond Penke; Gyula Telegdy
Role of different neurotransmitter systems in the cholecystokinin octapeptide-induced anxiogenic response in rats.
Neuropeptides 1997;31(3):281-5.
1997: Zoltán Farkas; Magdolna Pákáski; Botond Penke; Péter Kása
Acetylcholine release induced in vitro by beta-amyloid and its fragments.
Neurobiology (Budapest, Hungary) 1997;5(1):59-61.
1996: Ilona Laczkó; Elemér Vass; Katalin Soós; Jozsef Varga; S Száraz; Miklós Hollósi; Botond Penke
Ca(2+)- and Al(3+)-induced conformational transitions of amyloid fragment H-Ile-Ile-Gly-Leu-Met-NH2.
Archives of biochemistry and biophysics 1996;335(2):381-7.
1996: M Pákáski; Zoltán Farkas; Katalin Soós; Botond Penke; Péter Kása
Role of Leu(34)-Met(35) in neurotoxicity caused by human beta-amyloid (1-42) peptide in vitro.
Neurobiology (Budapest, Hungary) 1996;4(3):273-4.
1996: Annamária Kovács; Gyula Telegdy; G Tóth; Botond Penke
The involvement of nitric oxide (NO) in the CGRP-induced behavior of rats.
Peptides 1996;17(7):1183-7.
1995: Tibor Harkany; GI de Jong; Katalin Soós; Botond Penke; Paul G M Luiten; Karoly Gulya
Beta-amyloid (1-42) affects cholinergic but not parvalbumin-containing neurons in the septal complex of the rat.
Brain research 1995;698(1-2):270-4.
1995: János Pataricza; G K Toth; Botond Penke; J Hohn; Julius Gy Papp
Effect of selective inhibition of potassium channels on vasorelaxing response to cromakalim, nitroglycerin and nitric oxide of canine coronary arteries.
The Journal of pharmacy and pharmacology 1995;47(11):921-5.
1995: Tibor Harkany; Z Lengyel; Katalin Soós; Botond Penke; Paul G M Luiten; Karoly Gulya
Cholinotoxic effects of beta-amyloid (1-42) peptide on cortical projections of the rat nucleus basalis magnocellularis.
Brain research 1995;695(1):71-5.
1995: G K Tóth; János Pataricza; Tamás Janáky; M Mák; Márta Zarándi; Julius Gy Papp; Botond Penke
Synthesis of two peptide scorpion toxins and their use to investigate the aortic tissue regulation.
Peptides 1995;16(7):1167-72.
1994: Eva Rajnavölgyi; Z Nagy; István Kurucz; Péter Gogolák; G K Tóth; G Váradi; Botond Penke; Z Tigyi; Miklós Hollósi; János Gergely
T cell recognition of the posttranslationally cleaved intersubunit region of influenza virus hemagglutinin.
Molecular immunology 1994;31(18):1403-14.
1994: Ilona Laczkó; S Holly; Zoltan Kónya; Katalin Soós; Jozsef Varga; Miklós Hollósi; Botond Penke
Conformational mapping of amyloid peptides from the putative neurotoxic 25-35 region.
Biochemical and biophysical research communications 1994;205(1):120-6.
1994: Z Nagy; Eva Rajnavölgyi; Miklós Hollósi; G K Tóth; G Váradi; Botond Penke; I Tóth; Attila Horváth; János Gergely; István Kurucz
The intersubunit region of the influenza virus haemagglutinin is recognized by antibodies during infection.
Scandinavian journal of immunology 1994;40(3):281-91.
1994: Miklós Vecsernyés; A Török; I Jójárt; Ferenc Laczi; Botond Penke; János Julesz
Specific radioimmunoassay of oxytocin in rat plasma.
Endocrine regulations 1994;28(3):145-50.
1994: G Váradi; G K Tóth; Botond Penke
A new synthesis of Rink's polymer, 4-(2',4'-dimethoxyphenylhydroxymethyl)phenoxymethylpolystyrene .
International journal of peptide and protein research 1994;43(1):29-30.
1993: G K Tóth; G Váradi; Z Nagy; Eva Monostori; Botond Penke; Zoltán Hegedüs; István Andó; G Fazekas; István Kurucz; M Mák
Branched polypeptides as antigens for influenza virus hemagglutinin and T-cell receptor subunits.
Peptide research 1993;6(5):272-80.
1993: E Biró; Zoltan Sarnyai; Botond Penke; Gyula Szabó; Gyula Telegdy
Role of endogenous corticotropin-releasing factor in mediation of neuroendocrine and behavioral responses to cholecystokinin octapeptide sulfate ester in rats.
Neuroendocrinology 1993;57(2):340-5.
1992: Zoltan Sarnyai; E Bíró; Botond Penke; Gyula Telegdy
The cocaine-induced elevation of plasma corticosterone is mediated by endogenous corticotropin-releasing factor (CRF) in rats.
Brain research 1992;589(1):154-6.
1992: Miklós Hollósi; A A Ismail; Henry H Mantsch; Botond Penke; I G Varadi; G K Toth; Ilona Laczkó; István Kurucz; Z Nagy; G D Fasman
Conformational and functional properties of peptides covering the intersubunit region of influenza virus hemagglutinin.
European journal of biochemistry / FEBS 1992;206(2):421-5.
1992: A Bidzseranova; J Gueron; G Tóth; Botond Penke; Gyula Telegdy
Effect of atrial natriuretic peptide on dopa potentiation in mice.
Brain research bulletin 1992;28(5):767-8.
1992: A Bidzseranova; J Gueron; G Tóth; Botond Penke; Jozsef Varga; Gyula Telegdy
Behavioral effects of atrial and brain natriuretic peptides in rats.
Neuroreport 1992;3(3):283-5.
1992: A Bidzseranova; J Gueron; G Tóth; Botond Penke; Gyula Telegdy
Effect of atrial natriuretic peptide on apomorphine-induced stereotyped cage-climbing behavior in mice.
European journal of pharmacology 1992;211(3):411-4.
1992: Zoltan Sarnyai; J Höhn; G Szabó; Botond Penke
Critical role of endogenous corticotropin-releasing factor (CRF) in the mediation of the behavioral action of cocaine in rats.
Life sciences 1992;51(26):2019-24.
1991: A Bidzseranova; J Gueron; Botond Penke; Gyula Telegdy
The effects of atrial natriuretic peptide on active avoidance behavior in rats. The role of transmitters.
Pharmacology, biochemistry, and behavior 1991;40(1):61-4.
1991: A Bidzseranova; Botond Penke; G Tóth; Gyula Telegdy
The effects of atrial natriuretic peptide on electroconvulsive shock-induced amnesia in rats. Transmitter-mediated action.
Neuropeptides 1991;19(2):103-6.
1989: Ferenc László; Imre Pávó; Botond Penke; G A Bálint
Protective effect of an orally administered, highly potent somatostatin analog (RC-121) against absolute ethanol-induced hemorrhagic erosions of the rat gastric mucosa.
Life sciences 1989;44(21):1573-8.
1989: Ferenc László; Imre Pávó; Botond Penke; G A Bálint
The cytoprotective effect of the desamino-D-Trp 7-10 fragment of somatostatin on ethanol-induced erosions in the rat stomach.
Acta physiologica Hungarica 1989;73(2-3):199-202.
1988: Ferenc Laczi; Miklós Vecsernyés; G L Kovács; Botond Penke; I Jójárt; Tamás Janáky; Gyula Telegdy; Ferenc László
The effect of atrial natriuretic factor on arginine-8-vasopressin and oxytocin levels in various brain regions and plasma.
Experimental and clinical endocrinology 1988;92(3):328-34.
1987: Ferenc László; Imre Pávó; Botond Penke; G A Bálint
The effects of somatostatin and some of its tetrapeptide fragments on ethanol-induced gastric mucosal erosion in rat.
Life sciences 1987;41(9):1123-6.
1987: T Kádár; L Borda; Márta Zarándi; Botond Penke; K Kovács; G Telegdy
Inhibition of electroshock-induced seizures by cholecystokinin-related peptides in mice.
Acta physiologica Hungarica 1987;69(1):43-50.
1986: Botond Penke; Márta Zarándi; J R Varga; G K Tóth; K Kovács; B Szajáni
Targeted immobilization of neurotransmitters and neuropeptides on agarose and on Acrylex polymers.
Journal of chromatography 1986;376():307-14.
1986: T Kádár; Botond Penke; K Kovács; G Telegdy
Inhibition of feeding by the C-terminal tetrapeptide fragment of cholecystokinin in a novel environment.
Neuropeptides 1986;7(2):97-108.
1985: T Kádár; Botond Penke; A Pesti; G Telegdy
Multiple treatment potentiates the anticonvulsive activity of cholecystokinin octapeptides.
Peptides 1985;6(6):1009-14.
1985: T Kádár; L Borda; Botond Penke; K Kovács; G Telegdy
Cataleptogenic and anticataleptic activity produced by cholecystokinin octapeptides in mice.
Neuropeptides 1985;6(3):259-68.
1985: T Kádár; Botond Penke; K Kovács; G Telegdy
Inhibition of haloperidol-induced catalepsy by cholecystokinin octapeptides after central administration to rats.
Neuropharmacology 1985;24(6):577-80.
1985: T Kádár; Botond Penke; K Kovács; G Telegdy
Depression of rat feeding in familiar and novel environment by sulfated and nonsulfated cholecystokinin octapeptide.
Physiology & behavior 1985;34(3):395-400.
1985: Botond Penke; G L Kovács; J Zsigó; T Kádár; G Szabó; K Kovács; G Telegdy
In vivo sulfation of cholecystokinin octapeptide. Possible interactions of the two forms of cholecystokinin with dopamine in the brain.
Annals of the New York Academy of Sciences 1985;448():293-305.
1984: T Kádár; M Várszegi; S K Sudakov; Botond Penke; G Telegdy
Changes in brain monoamine levels of rats during cholecystokinin octapeptide-induced suppression of feeding.
Pharmacology, biochemistry, and behavior 1984;21(3):339-44.
1984: T Kádár; A Pesti; Botond Penke; G Telegdy
Inhibition of seizures induced by picrotoxin and electroshock by cholecystokinin octapeptides and their fragments in rats after intracerebroventricular administration.
Neuropharmacology 1984;23(8):955-61.
1984: G Telegdy; T Kádár; K Kovács; Botond Penke
The inhibition of tail-pinch-induced food intake by cholecystokinin octapeptides and their fragments.
Life sciences 1984;35(2):163-70.
1984: T Kádár; Botond Penke; K Kovács; G Telegdy
The effects of sulfated and nonsulfated cholecystokinin octapeptides on electroconvulsive shock-induced retrograde amnesia after intracerebroventricular administration in rats.
Neuropeptides 1984;4(2):127-35.
1983: T Kádár; A Pesti; Botond Penke; G Tóth; Márta Zarándi; G Telegdy
Structure-activity and dose-effect relationships of the antagonism of picrotoxin-induced seizures by cholecystokinin, fragments and analogues of cholecystokinin in mice.
Neuropharmacology 1983;22(10):1223-9.
1981: M Fekete; M Várszegi; T Kádár; Botond Penke; K Kovács; G Telegdy
Effect of cholecystokinin octapeptide sulphate ester on brain monoamines in the rat.
Acta physiologica Academiae Scientiarum Hungaricae 1981;57(1):37-46.
1981: M Fekete; T Kádár; Botond Penke; K Kovács; G Telegdy
Influence of cholecystokinin octapeptide sulfate ester on brain monoamine metabolism in rats.
Journal of neural transmission 1981;50(2-4):81-8.