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Milena Penkowa

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Dan Sonne Pedersen; Mie Ostergaard Pedersen; Milena Penkowa; Jørgen Rungby; Meredin Stoltenberg; Gorm Danscher; Pil Møntegaard Fredericia; Agnete Larsen
Metallic gold slows disease progression, reduces cell death and induces astrogliosis while simultaneously increasing stem cell responses in an EAE rat model of multiple sclerosis.
Linda J Locht; Sara Markholt; Mie Ø Pedersen; Milena Penkowa; Bo Martin Bibby; Agnete Larsen; Meredin Stoltenberg; Jørgen Rungby
Metallic silver fragments cause massive tissue loss in the mouse brain.
Andrew Core; Casper Hempel; Jørgen A L Kurtzhals; Milena Penkowa
Plasmodium berghei ANKA: erythropoietin activates neural stem cells in an experimental cerebral malaria model.

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All Publications

2012: Dan Sonne Pedersen; Mie Ostergaard Pedersen; Milena Penkowa; Jørgen Rungby; Meredin Stoltenberg; Gorm Danscher; Pil Møntegaard Fredericia; Agnete Larsen
Metallic gold slows disease progression, reduces cell death and induces astrogliosis while simultaneously increasing stem cell responses in an EAE rat model of multiple sclerosis.
Histochemistry and cell biology 2012;138(5):787-802.
2011: Linda J Locht; Sara Markholt; Mie Ø Pedersen; Milena Penkowa; Bo Martin Bibby; Agnete Larsen; Meredin Stoltenberg; Jørgen Rungby
Metallic silver fragments cause massive tissue loss in the mouse brain.
Basic & clinical pharmacology & toxicology 2011;109(1):1-10.
2011: Andrew Core; Casper Hempel; Jørgen A L Kurtzhals; Milena Penkowa
Plasmodium berghei ANKA: erythropoietin activates neural stem cells in an experimental cerebral malaria model.
Experimental parasitology 2011;127(2):500-5.
2010: Kirsten A Wunderlich; Thierry Leveillard; Milena Penkowa; Eberhart Zrenner; Maria-Thereza R Perez
Altered expression of metallothionein-I and -II and their receptor megalin in inherited photoreceptor degeneration.
Investigative ophthalmology & visual science 2010;51(9):4809-20.
2010: Brian DellaValle; Casper Hempel; Jørgen A L Kurtzhals; Milena Penkowa
In vivo expression of neuroglobin in reactive astrocytes during neuropathology in murine models of traumatic brain injury, cerebral malaria, and autoimmune encephalitis.
Glia 2010;58(10):1220-7.
2010: Milena Penkowa
[Inflammation and neuroregeneration--professor accession].
Ugeskrift for laeger 2010;172(17):1293-6.
2010: M Ashina; Jesper Filtenborg Tvedskov; K Lipka; John Bilello; Milena Penkowa; Jes Olesen
Matrix metalloproteinases during and outside of migraine attacks without aura.
Cephalalgia : an international journal of headache 2010;30(3):303-10.
2010: Mie Ø Pedersen; Per Boye Hansen; Signe L Nielsen; Milena Penkowa
Metallothionein-I + II and receptor megalin are altered in relation to oxidative stress in cerebral lymphomas.
Leukemia & lymphoma 2010;51(2):314-28.
2010: Mie Østergaard Pedersen; Agnete Larsen; Michael Stoltenberg; Milena Penkowa
Bio-released gold ions modulate expression of neuroprotective and hematopoietic factors after brain injury.
Brain research 2010;1307():1-13.
2010: Anders D Skjolding; Ian J Rowland; Lise V Søgaard; Jeppe Praetorius; Milena Penkowa; Marianne Juhler
Hydrocephalus induces dynamic spatiotemporal regulation of aquaporin-4 expression in the rat brain.
Cerebrospinal fluid research 2010;7():20.
2010: Peter Doering; Meredin Stoltenberg; Milena Penkowa; Jørgen Rungby; Agnete Larsen; Gorm Danscher
Chemical blocking of zinc ions in CNS increases neuronal damage following traumatic brain injury (TBI) in mice.
PloS one 2010;5(4):e10131.
2009: Mikkel Faurschou; Milena Penkowa; C B Andersen; Henrik Starklint; Steffen Jacobsen
Renal cell apoptosis in human lupus nephritis: a histological study.
Lupus 2009;18(11):994-9.
2009: Johanne Wirenfeldt Asmussen; Marie Louise Von Sperling; Milena Penkowa
Intraneuronal signaling pathways of metallothionein.
Journal of neuroscience research 2009;87(13):2926-36.
2009: Mie Ø Pedersen; Rikke Jensen; Dan S Pedersen; Anders D Skjolding; Casper Hempel; Lasse Maretty; Milena Penkowa
Metallothionein-I+II in neuroprotection.
BioFactors (Oxford, England) 2009;35(4):315-25.
2009: V B Matthews; M-B Aström; M H S Chan; Clinton R Bruce; K S Krabbe; Oja Prelovsek; T Akerström; C Yfanti; C Broholm; Ole Hartvig Mortensen; Milena Penkowa; Pernille Hojman; A Zankari; Matthew J Watt; H Bruunsgaard; Bente Klarlund Pedersen; Mark A Febbraio
Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase.
Diabetologia 2009;52(7):1409-18.
2009: Mie Ostergaard Pedersen; Agnete Larsen; Dan Sonne Pedersen; Michael Stoltenberg; Milena Penkowa
Metallic gold reduces TNFalpha expression, oxidative DNA damage and pro-apoptotic signals after experimental brain injury.
Brain research 2009;1271():103-13.
2009: Milena Penkowa; Brit Ladegaard Sørensen; Signe Lidou Nielsen; Per Boye Hansen
Metallothionein as a useful marker in Hodgkin lymphoma subclassification.
Leukemia & lymphoma 2009;50(2):200-10.
2009: Mie Ø Pedersen; Agnete Larsen; Michael Stoltenberg; Milena Penkowa
The role of metallothionein in oncogenesis and cancer prognosis.
Progress in histochemistry and cytochemistry 2009;44(1):29-64.
2009: Mie Ø Pedersen; Agnete Larsen; Michael Stoltenberg; Milena Penkowa
Cell death in the injured brain: roles of metallothioneins.
Progress in histochemistry and cytochemistry 2009;44(1):1-27.
2008: Agnete Larsen; Kristian Kolind; Dan Sonne Pedersen; Peter Doering; Mie Ostergaard Pedersen; Gorm Danscher; Milena Penkowa; Meredin Stoltenberg
Gold ions bio-released from metallic gold particles reduce inflammation and apoptosis and increase the regenerative responses in focal brain injury.
Histochemistry and cell biology 2008;130(4):681-92.
2008: Martin V Pedersen; Rehannah Borup Helweg-Larsen; Omid Niazi; Vladimir Berezin; Elisabeth Bock; Milena Penkowa
The synthetic NCAM-derived peptide, FGL, modulates the transcriptional response to traumatic brain injury.
Neuroscience letters 2008;437(2):148-53.
2008: Roger S Chung; Milena Penkowa; Justin Dittmann; CE King; Carole Bartlett; Johanne W Asmussen; Juan Hidalgo; Javier Carrasco; Yee Kee J Leung; Adam K Walker; Samantha J Fung; Sarah A Dunlop; Melinda Fitzgerald; Lyn D Beazley; Meng Inn Chuah; James C Vickers; Adrian K West
Redefining the role of metallothionein within the injured brain: extracellular metallothioneins play an important role in the astrocyte-neuron response to injury.
The Journal of biological chemistry 2008;283(22):15349-58.
2008: Mie Østergaard Pedersen; Dan Sonne Pedersen; Michael Pedersen; Milena Penkowa
[Neisseria meningitidis. The pathophysiological role of lipopolysaccharides in association with meningococcal disease and septic shock].
Ugeskrift for laeger 2008;170(6):421-6.
2008: Albert Quintana; Amalia Molinero; Rehannah Borup; Omid Niazi; Iain L Campbell; Milena Penkowa; Juan Hidalgo
Effect of astrocyte-targeted production of IL-6 on traumatic brain injury and its impact on the cortical transcriptome.
Developmental neurobiology 2008;68(2):195-208.
2008: Mikkel Faurschou; Milena Penkowa; Claus Bøgelund Andersen; Henrik Starklint; Steffen Jacobsen
The renal metallothionein expression profile is altered in human lupus nephritis.
Arthritis research & therapy 2008;10(4):R76.
2008: Lothar Wiese; Casper Hempel; Milena Penkowa; Nikolai Kirkby; Jørgen A L Kurtzhals
Recombinant human erythropoietin increases survival and reduces neuronal apoptosis in a murine model of cerebral malaria.
Malaria journal 2008;7():3.
2008: Malene Ambjørn; Johanne W Asmussen; Mats Lindstam; Kamil Gotfryd; Christian Jacobsen; Vladislav V Kiselyov; Søren K Moestrup; Milena Penkowa; Elisabeth Bock; Vladimir Berezin
Metallothionein and a peptide modeled after metallothionein, EmtinB, induce neuronal differentiation and survival through binding to receptors of the low-density lipoprotein receptor family.
Journal of neurochemistry 2008;104(1):21-37.
2007: Peter Plomgaard; Anders Rinnov Nielsen; Christian Fischer; Ole Hartvig Mortensen; C Broholm; Milena Penkowa; Rikke Krogh-Madsen; Christian Erikstrup; Birgitte Lindegaard; A M W Petersen; S Taudorf; Bente Klarlund Pedersen
Associations between insulin resistance and TNF-alpha in plasma, skeletal muscle and adipose tissue in humans with and without type 2 diabetes.
Diabetologia 2007;50(12):2562-71.
2007: Anders Rinnov Nielsen; Remi Mounier; Peter Plomgaard; Ole Hartvig Mortensen; Milena Penkowa; Tobias Speerschneider; Henriette Pilegaard; Bente Klarlund Pedersen
Expression of interleukin-15 in human skeletal muscle effect of exercise and muscle fibre type composition.
The Journal of physiology 2007;584(Pt 1):305-12.
2007: Albert Quintana; Amalia Molinero; Sergi Florit; Yasmina Manso; Gemma Comes; Javier Carrasco; Mercedes Giralt; Rehannah Borup; Omid Niazi; Iain L Campbell; Milena Penkowa; Juan Hidalgo
Diverging mechanisms for TNF-alpha receptors in normal mouse brains and in functional recovery after injury: From gene to behavior.
Journal of neuroscience research 2007;85(12):2668-85.
2007: A M W Petersen; Milena Penkowa; M Iversen; Lone Frydelund-Larsen; J L Andersen; Jann Mortensen; P Lange; Bente Klarlund Pedersen
Elevated levels of IL-18 in plasma and skeletal muscle in chronic obstructive pulmonary disease.
Lung 2007;185(3):161-71.
2007: Johan A Westberg; Martina Serlachius; Petri Lankila; Milena Penkowa; Juan Hidalgo; Leif C Andersson
Hypoxic preconditioning induces neuroprotective stanniocalcin-1 in brain via IL-6 signaling.
Stroke; a journal of cerebral circulation 2007;38(3):1025-30.
2007: Allan Evald Nielsen; Adam Bohr; Milena Penkowa
The Balance between Life and Death of Cells: Roles of Metallothioneins.
Biomarker insights 2007;1():99-111.
2007: Albert Quintana; Mercedes Giralt; Amalia Molinero; Iain L Campbell; Milena Penkowa; Juan Hidalgo
Analysis of the cerebral transcriptome in mice subjected to traumatic brain injury: importance of IL-6.
Neuroimmunomodulation 2007;14(3-4):139-43.
2007: Roger K Stankovic; Roger S Chung; Milena Penkowa
Metallothioneins I and II: neuroprotective significance during CNS pathology.
The international journal of biochemistry & cell biology 2007;39(3):484-9.
2007: Lone Frydelund-Larsen; Milena Penkowa; Thorbjorn Akerstrom; Alaa Zankari; Søren Nielsen; Bente Klarlund Pedersen
Exercise induces interleukin-8 receptor (CXCR2) expression in human skeletal muscle.
Experimental physiology 2007;92(1):233-40.
2006: Javier Carrasco; P Adlard; Carl W Cotman; Albert Quintana; Milena Penkowa; F Xu; William E Van Nostrand; Juan Hidalgo
Metallothionein-I and -III expression in animal models of Alzheimer disease.
Neuroscience 2006;143(4):911-22.
2006: Milena Penkowa; Mario Cáceres; Rehannah Borup; Omid Niazi; Christian Bjørn Poulsen; Albert Quintana; Amalia Molinero; Javier Carrasco; Sergi Florit; Mercedes Giralt; Juan Hidalgo
Novel roles for metallothionein-I + II (MT-I + II) in defense responses, neurogenesis, and tissue restoration after traumatic brain injury: insights from global gene expression profiling in wild-type and MT-I + II knockout mice.
Journal of neuroscience research 2006;84(7):1452-74.
2006: Juan Hidalgo; Milena Penkowa; Carmen Espejo; Eva M Martínez-Cáceres; Javier Carrasco; Albert Quintana; Amalia Molinero; Sergi Florit; Mercedes Giralt; Arantxa Ortega-Aznar
Expression of metallothionein-I, -II, and -III in Alzheimer disease and animal models of neuroinflammation.
Experimental biology and medicine (Maywood, N.J.) 2006;231(9):1450-8.
2006: Peter Plomgaard; Milena Penkowa; Lotte Leick; Bente Klarlund Pedersen; Bengt Saltin; Henriette Pilegaard
The mRNA expression profile of metabolic genes relative to MHC isoform pattern in human skeletal muscles.
Journal of applied physiology (Bethesda, Md. : 1985) 2006;101(3):817-25.
2006: Lothar Wiese; Jørgen A L Kurtzhals; Milena Penkowa
Neuronal apoptosis, metallothionein expression and proinflammatory responses during cerebral malaria in mice.
Experimental neurology 2006;200(1):216-26.
2006: Milena Penkowa
Metallothionein I + II expression and roles during neuropathology in the CNS.
Danish medical bulletin 2006;53(2):105-21.
2006: Milena Penkowa
Metallothioneins are multipurpose neuroprotectants during brain pathology.
The FEBS journal 2006;273(9):1857-70.
2006: Milena Penkowa; Laura Tio; Mercedes Giralt; Albert Quintana; Amalia Molinero; Sílvia Atrian; Milan Vasák; Juan Hidalgo
Specificity and divergence in the neurobiologic effects of different metallothioneins after brain injury.
Journal of neuroscience research 2006;83(6):974-84.
2006: Jaroslav P Novak; Seon-Young Kim; Jun Xu; Olga Modlich; David J Volsky; David Honys; Joan L Slonczewski; Douglas A Bell; Fred R Blattner; Eduardo Blumwald; Marjan Boerma; Manuel Cosio; Zoran Gatalica; Marian Hajduch; Juan Hidalgo; Roderick R McInnes; Merrill C Miller; Milena Penkowa; Michael S Rolph; Jordan Sottosanto; René St-Arnaud; Michael J Szego; David Twell; Charles Wang
Generalization of DNA microarray dispersion properties: microarray equivalent of t-distribution.
Biology direct 2006;1():27.
2005: Albert Quintana; Mercedes Giralt; Santiago Rojas; Milena Penkowa; Iain L Campbell; Juan Hidalgo; Amalia Molinero
Differential role of tumor necrosis factor receptors in mouse brain inflammatory responses in cryolesion brain injury.
Journal of neuroscience research 2005;82(5):701-16.
2005: Celena Scheede-Bergdahl; Milena Penkowa; Juan Hidalgo; David B Olsen; Peter Schjerling; Clara Prats; Robert Boushel; Flemming Dela
Metallothionein-mediated antioxidant defense system and its response to exercise training are impaired in human type 2 diabetes.
Diabetes 2005;54(11):3089-94.
2005: Pernille Keller; Milena Penkowa; Charlotte Keller; Adam Steensberg; Christian Fischer; Mercedes Giralt; Juan Hidalgo; Bente Klarlund Pedersen
Interleukin-6 receptor expression in contracting human skeletal muscle: regulating role of IL-6.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1181-3.
2005: Milena Penkowa; Pernille Keller; Charlotte Keller; Juan Hidalgo; Mercedes Giralt; Bente Klarlund Pedersen
Exercise-induced metallothionein expression in human skeletal muscle fibres.
Experimental physiology 2005;90(4):477-86.
2005: Thorbjorn Akerstrom; Adam Steensberg; Pernille Keller; Charlotte Keller; Milena Penkowa; Bente Klarlund Pedersen
Exercise induces interleukin-8 expression in human skeletal muscle.
The Journal of physiology 2005;563(Pt 2):507-16.
2005: Milena Penkowa; Sergi Florit; Mercedes Giralt; Albert Quintana; Amalia Molinero; Javier Carrasco; Juan Hidalgo
Metallothionein reduces central nervous system inflammation, neurodegeneration, and cell death following kainic acid-induced epileptic seizures.
Journal of neuroscience research 2005;79(4):522-34.
2005: Peter Plomgaard; Milena Penkowa; Bente Klarlund Pedersen
Fiber type specific expression of TNF-alpha, IL-6 and IL-18 in human skeletal muscles.
Exercise immunology review 2005;11():53-63.
2005: Carmen Espejo; Milena Penkowa; M Demestre; Xavier Montalban; Eva M Martínez-Cáceres
Time-course expression of CNS inflammatory, neurodegenerative tissue repair markers and metallothioneins during experimental autoimmune encephalomyelitis.
Neuroscience 2005;132(4):1135-49.
2005: Christian Bjørn Poulsen; Milena Penkowa; Rehannah Borup; Omid Niazi; Mario Cáceres; Albert Quintana; Amalia Molinero; Javier Carrasco; Mercedes Giralt; Juan Hidalgo
Brain response to traumatic brain injury in wild-type and interleukin-6 knockout mice: a microarray analysis.
Journal of neurochemistry 2005;92(2):417-32.
2004: Christian Fischer; Natalie Hiscock; Milena Penkowa; Samar Basu; Bengt Vessby; Anders Kallner; Lars-Börje Sjöberg; Bente Klarlund Pedersen
Supplementation with vitamins C and E inhibits the release of interleukin-6 from contracting human skeletal muscle.
The Journal of physiology 2004;558(Pt 2):633-45.
2004: Milena Penkowa; Albert Quintana; Javier Carrasco; Mercedes Giralt; Amalia Molinero; Juan Hidalgo
Metallothionein prevents neurodegeneration and central nervous system cell death after treatment with gliotoxin 6-aminonicotinamide.
Journal of neuroscience research 2004;77(1):35-53.
2003: Lene B Køhler; Vladimir Berezin; Elisabeth Bock; Milena Penkowa
The role of metallothionein II in neuronal differentiation and survival.
Brain research 2003;992(1):128-36.
2003: Milena Penkowa; Charlotte Keller; Pernille Keller; Sune Jauffred; Bente Klarlund Pedersen
Immunohistochemical detection of interleukin-6 in human skeletal muscle fibers following exercise.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(14):2166-8.
2003: Milena Penkowa; Jordi Camats; Hanne Hadberg; Albert Quintana; Santiago Rojas; Mercedes Giralt; Amalia Molinero; Iain L Campbell; Juan Hidalgo
Astrocyte-targeted expression of interleukin-6 protects the central nervous system during neuroglial degeneration induced by 6-aminonicotinamide.
Journal of neuroscience research 2003;73(4):481-96.
2003: Milena Penkowa; Carmen Espejo; Arantxa Ortega-Aznar; Juan Hidalgo; Xavier Montalban; Eva M Martínez-Cáceres
Metallothionein expression in the central nervous system of multiple sclerosis patients.
Cellular and molecular life sciences : CMLS 2003;60(6):1258-66.
2003: Dolores Ceballos; Natalia Lago; Enrique Verdú; Milena Penkowa; Javier Carrasco; Xavier Navarro; Richard D Palmiter; Juan Hidalgo
Role of metallothioneins in peripheral nerve function and regeneration.
Cellular and molecular life sciences : CMLS 2003;60(6):1209-16.
2003: Milena Penkowa; Mercedes Giralt; Natalia Lago; Jordi Camats; Javier Carrasco; Joaquin Hernández; Amalia Molinero; Iain L Campbell; Juan Hidalgo
Astrocyte-targeted expression of IL-6 protects the CNS against a focal brain injury.
Experimental neurology 2003;181(2):130-48.
2003: Javier Carrasco; Milena Penkowa; Mercedes Giralt; Jordi Camats; Amalia Molinero; Iain L Campbell; Richard D Palmiter; Juan Hidalgo
Role of metallothionein-III following central nervous system damage.
Neurobiology of disease 2003;13(1):22-36.
2003: Milena Penkowa; Juan Hidalgo
Treatment with metallothionein prevents demyelination and axonal damage and increases oligodendrocyte precursors and tissue repair during experimental autoimmune encephalomyelitis.
Journal of neuroscience research 2003;72(5):574-86.
2003: Milena Penkowa; Jordi Camats; Mercedes Giralt; Amalia Molinero; Joaquín Hernández; Javier Carrasco; Iain L Campbell; Juan Hidalgo
Metallothionein-I overexpression alters brain inflammation and stimulates brain repair in transgenic mice with astrocyte-targeted interleukin-6 expression.
Glia 2003;42(3):287-306.
2003: Amalia Molinero; Milena Penkowa; Joaquín Hernández; Jordi Camats; Mercedes Giralt; Natalia Lago; Javier Carrasco; Iain L Campbell; Juan Hidalgo
Metallothionein-I overexpression decreases brain pathology in transgenic mice with astrocyte-targeted expression of interleukin-6.
Journal of neuropathology and experimental neurology 2003;62(3):315-28.
2003: Maike Hartlage-Rübsamen; Ulrike Zeitschel; Jenny Apelt; Ulrich Gärtner; Heike Franke; Tobias Stahl; Albrecht Günther; Reinhard Schliebs; Milena Penkowa; Volker Bigl; Steffen Rossner
Astrocytic expression of the Alzheimer's disease beta-secretase (BACE1) is stimulus-dependent.
Glia 2003;41(2):169-79.
2003: Milena Penkowa; Carmen Espejo; Eva M Martínez-Cáceres; Xavier Montalban; Juan Hidalgo
Increased demyelination and axonal damage in metallothionein I+II-deficient mice during experimental autoimmune encephalomyelitis.
Cellular and molecular life sciences : CMLS 2003;60(1):185-97.
2002: Carmen Espejo; Milena Penkowa; Irene Sáez-Torres; Juan Hidalgo; Agustina García; Xavier Montalban; Eva M Martínez-Cáceres
Interferon-gamma regulates oxidative stress during experimental autoimmune encephalomyelitis.
Experimental neurology 2002;177(1):21-31.
2002: Milena Penkowa; Christian Bjørn Poulsen; Javier Carrasco; Juan Hidalgo
M-CSF deficiency leads to reduced metallothioneins I and II expression and increased tissue damage in the brain stem after 6-aminonicotinamide treatment.
Experimental neurology 2002;176(2):308-21.
2002: Mercedes Giralt; Milena Penkowa; Joaquín Hernández; Amalia Molinero; Javier Carrasco; Natalia Lago; Jordi Camats; Iain L Campbell; Juan Hidalgo
Metallothionein-1+2 deficiency increases brain pathology in transgenic mice with astrocyte-targeted expression of interleukin 6.
Neurobiology of disease 2002;9(3):319-38.
2002: Milena Penkowa; Mercedes Giralt; Jordi Camats; Juan Hidalgo
Metallothionein 1+2 protect the CNS during neuroglial degeneration induced by 6-aminonicotinamide.
The Journal of comparative neurology 2002;444(2):174-89.
2002: Juan Hidalgo; Milena Penkowa; Mercedes Giralt; Javier Carrasco; Amalia Molinero
Metallothionein expression and oxidative stress in the brain.
Methods in enzymology 2002;348():238-49.
2002: Mercedes Giralt; Milena Penkowa; Natalia Lago; Amalia Molinero; Juan Hidalgo
Metallothionein-1+2 protect the CNS after a focal brain injury.
Experimental neurology 2002;173(1):114-28.
2001: Carmen Espejo; Milena Penkowa; Irene Sáez-Torres; Jordi Xaus; Antonio Celada; Xavier Montalban; Eva M Martínez-Cáceres
Treatment with anti-interferon-gamma monoclonal antibodies modifies experimental autoimmune encephalomyelitis in interferon-gamma receptor knockout mice.
Experimental neurology 2001;172(2):460-8.
2001: Milena Penkowa; Carmen Espejo; Eva M Martínez-Cáceres; Christian Bjørn Poulsen; Xavier Montalban; Juan Hidalgo
Altered inflammatory response and increased neurodegeneration in metallothionein I+II deficient mice during experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 2001;119(2):248-60.
2001: Milena Penkowa; Juan Hidalgo
Metallothionein treatment reduces proinflammatory cytokines IL-6 and TNF-alpha and apoptotic cell death during experimental autoimmune encephalomyelitis (EAE).
Experimental neurology 2001;170(1):1-14.
2001: Milena Penkowa; Mercedes Giralt; P S Thomsen; Javier Carrasco; Juan Hidalgo
Zinc or copper deficiency-induced impaired inflammatory response to brain trauma may be caused by the concomitant metallothionein changes.
Journal of neurotrauma 2001;18(4):447-63.
2001: Carmen Espejo; Javier Carrasco; Juan Hidalgo; Milena Penkowa; A Garcia; Irene Sáez-Torres; Eva M Martínez-Cáceres
Differential expression of metallothioneins in the CNS of mice with experimental autoimmune encephalomyelitis.
Neuroscience 2001;105(4):1055-65.
2001: Milena Penkowa; Amalia Molinero; Javier Carrasco; Juan Hidalgo
Interleukin-6 deficiency reduces the brain inflammatory response and increases oxidative stress and neurodegeneration after kainic acid-induced seizures.
Neuroscience 2001;102(4):805-18.
2000: Milena Penkowa; Mercedes Giralt; Javier Carrasco; Hanne Hadberg; Juan Hidalgo
Impaired inflammatory response and increased oxidative stress and neurodegeneration after brain injury in interleukin-6-deficient mice.
Glia 2000;32(3):271-85.
2000: Milena Penkowa; Juan Hidalgo
Metallothionein I+II expression and their role in experimental autoimmune encephalomyelitis.
Glia 2000;32(3):247-63.
2000: Milena Penkowa; Javier Carrasco; Mercedes Giralt; Amalia Molinero; Joaquín Hernández; Iain L Campbell; Juan Hidalgo
Altered central nervous system cytokine-growth factor expression profiles and angiogenesis in metallothionein-I+II deficient mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(8):1174-89.
2000: Javier Carrasco; Milena Penkowa; Hanne Hadberg; Amalia Molinero; Juan Hidalgo
Enhanced seizures and hippocampal neurodegeneration following kainic acid-induced seizures in metallothionein-I + II-deficient mice.
The European journal of neuroscience 2000;12(7):2311-22.
2000: Milena Penkowa; Juan Hidalgo
IL-6 deficiency leads to reduced metallothionein-I+II expression and increased oxidative stress in the brain stem after 6-aminonicotinamide treatment.
Experimental neurology 2000;163(1):72-84.
2000: Javier Carrasco; Mercedes Giralt; Milena Penkowa; A K Stalder; I L Campbell; Juan Hidalgo
Metallothioneins are upregulated in symptomatic mice with astrocyte-targeted expression of tumor necrosis factor-alpha.
Experimental neurology 2000;163(1):46-54.
1999: Javier Carrasco; Mercedes Giralt; Amalia Molinero; Milena Penkowa; Torben Moos; Juan Hidalgo
Metallothionein (MT)-III: generation of polyclonal antibodies, comparison with MT-I+II in the freeze lesioned rat brain and in a bioassay with astrocytes, and analysis of Alzheimer's disease brains.
Journal of neurotrauma 1999;16(11):1115-29.
1999: Milena Penkowa; H Nielsen; Juan Hidalgo; N Bernth; Torben Moos
Distribution of metallothionein I + II and vesicular zinc in the developing central nervous system: correlative study in the rat.
The Journal of comparative neurology 1999;412(2):303-18.
1999: Milena Penkowa; Javier Carrasco; Mercedes Giralt; Torben Moos; Juan Hidalgo
CNS wound healing is severely depressed in metallothionein I- and II-deficient mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(7):2535-45.
1999: Milena Penkowa; Mercedes Giralt; Torben Moos; P S Thomsen; J Hernández; Juan Hidalgo
Impaired inflammatory response to glial cell death in genetically metallothionein-I- and -II-deficient mice.
Experimental neurology 1999;156(1):149-64.
1999: Milena Penkowa; Torben Moos; Javier Carrasco; Hanne Hadberg; Amalia Molinero; H Bluethmann; Juan Hidalgo
Strongly compromised inflammatory response to brain injury in interleukin-6-deficient mice.
Glia 1999;25(4):343-57.
1997: Milena Penkowa; Juan Hidalgo; Torben Moos
Increased astrocytic expression of metallothioneins I + II in brainstem of adult rats treated with 6-aminonicotinamide.
Brain research 1997;774(1-2):256-9.
1995: Milena Penkowa; Torben Moos
Disruption of the blood-brain interface in neonatal rat neocortex induces a transient expression of metallothionein in reactive astrocytes.
Glia 1995;13(3):217-27.