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Subramaniam Pennathur

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Bing Pan; Ling Pan; Subramaniam Pennathur; Hui Ren; Xiaoli Shen; Belinda Willard; Baoqi Yu; Y Eugene Chen; Siyu Kang; Jinge Kong; Xiuli Li; Yijing Ma; Chenguang Niu; Lingyun Zu; Lemin Zheng
High-density lipoprotein nitration and chlorination catalyzed by myeloperoxidase impair its effect of promoting endothelial repair.
Katya B Rubinow; Kelly D Smith; Anuradha Vivekanandan-Giri; Valerie Z Wall; Carolyn Albert; Bardia Askari; Karol Bomsztyk; Roger J Davis; David A Ford; Myoung Sook Han; Marvin A Lai; Daniel Mar; Joel Nelson; Subramaniam Pennathur; Karin E Bornfeldt
Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages.
Ritika Khandpur; Jason S Knight; Sam Li; Rajiv M Patel; Subramaniam Pennathur; Venkataraman Subramanian; Paul Thompson; Anuradha Vivekanandan-Giri; Srilakshmi Yalavarthi; Carmelo Carmona-Rivera; Pojen Chen; David A Fox; Sean Friday; Alison Gizinski; Mariana J Kaplan
NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis.

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2013: Bing Pan; Ling Pan; Subramaniam Pennathur; Hui Ren; Xiaoli Shen; Belinda Willard; Baoqi Yu; Y Eugene Chen; Siyu Kang; Jinge Kong; Xiuli Li; Yijing Ma; Chenguang Niu; Lingyun Zu; Lemin Zheng
High-density lipoprotein nitration and chlorination catalyzed by myeloperoxidase impair its effect of promoting endothelial repair.
Free radical biology & medicine 2013;60():272-81.
2013: Katya B Rubinow; Kelly D Smith; Anuradha Vivekanandan-Giri; Valerie Z Wall; Carolyn Albert; Bardia Askari; Karol Bomsztyk; Roger J Davis; David A Ford; Myoung Sook Han; Marvin A Lai; Daniel Mar; Joel Nelson; Subramaniam Pennathur; Karin E Bornfeldt
Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages.
The Journal of biological chemistry 2013;288(14):9957-70.
2013: Ritika Khandpur; Jason S Knight; Sam Li; Rajiv M Patel; Subramaniam Pennathur; Venkataraman Subramanian; Paul Thompson; Anuradha Vivekanandan-Giri; Srilakshmi Yalavarthi; Carmelo Carmona-Rivera; Pojen Chen; David A Fox; Sean Friday; Alison Gizinski; Mariana J Kaplan
NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis.
Science translational medicine 2013;5(178):178ra40.
2013: Satyan Lakshminrusimha; Lori C Nielsen; Subramaniam Pennathur; Bruce A Davidson; Sylvia F Gugino; Jadwiga D Helinski; Paul R Knight; James A Russell; Madathilparambil V Suresh; Bi Yu; Lixia Zeng; Krishnan Raghavendran
Role of pulmonary artery reactivity and nitric oxide in injury and inflammation following lung contusion.
Shock (Augusta, Ga.) 2013;39(3):278-85.
2013: Xin Li; Subramaniam Pennathur; Jean E Schaffer; Xia Shen; Kyoichiro Tsuchiya; Anuradha Vivekanandan-Giri; Rosalind A Coleman; Oscar Gonzalez; Priya Handa; Jenny E Kanter; Francis Kim; Farah Kramer; Shelley Barnhart; Karin E Bornfeldt
Endothelial acyl-CoA synthetase 1 is not required for inflammatory and apoptotic effects of a saturated fatty acid-rich environment.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(2):232-40.
2013: Lucy M Hinder; Lisa L McLean; Subramaniam Pennathur; Anuradha Vivekanandan-Giri; Eva L Feldman
Decreased glycolytic and tricarboxylic acid cycle intermediates coincide with peripheral nervous system oxidative stress in a murine model of type 2 diabetes.
The Journal of endocrinology 2013;216(1):1-11.
2012: Seth G Thacker; Anuradha Vivekanandan-Giri; Hui Wang; Wenpu Zhao; Alisa E Koch; Wei Luo; Subramaniam Pennathur; Bradley J Rabquer; Carolyne K Smith; Anne Davidson; Daniel T Eitzman; Mariana J Kaplan
Type I interferons modulate vascular function, repair, thrombosis, and plaque progression in murine models of lupus and atherosclerosis.
Arthritis and rheumatism 2012;64(9):2975-85.
2012: Anna V Mathew; Subramaniam Pennathur
Metabolic signature of CKD: the search continues.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2012;60(2):173-5.
2012: Claudiu V Komorowsky; Frank C Brosius III; Subramaniam Pennathur; Matthias Kretzler
Perspectives on systems biology applications in diabetic kidney disease.
Journal of cardiovascular translational research 2012;5(4):491-508.
2012: Lucy M Hinder; Subramaniam Pennathur; Andrea M Vincent; Charles F Burant; Eva L Feldman
Bioenergetics in diabetic neuropathy: what we need to know.
Journal of the peripheral nervous system : JPNS 2012;17 Suppl 2():10-4.
2012: Jessica L Slocum; Michael Heung; Subramaniam Pennathur
Marking renal injury: can we move beyond serum creatinine?
Translational research : the journal of laboratory and clinical medicine 2012;159(4):277-89.
2012: Chang Yeop Han; Renee LeBoeuf; Mohamed Omer; Subramaniam Pennathur; Ian R Sweet; Tomio Umemoto; E Dale Abel; Carolyn L Buller; Tsuyoshi Chiba; Laura J Den Hartigh; Alan Chait
NADPH oxidase-derived reactive oxygen species increases expression of monocyte chemotactic factor genes in cultured adipocytes.
The Journal of biological chemistry 2012;287(13):10379-93.
2012: Jenny E Kanter; Farah Kramer; Lei O Li; Subramaniam Pennathur; Susan Potter-Perigo; Srinath Sanda; Charles N Serhan; Thad Vickery; Anuradha Vivekanandan-Giri; Thomas N Wight; Wei Yuan; Michelle M Averill; Shelley Barnhart; Lev Becker; Kathleen R Braun; Alan Chait; Rosalind A Coleman; Jay W Heinecke; Karin E Bornfeldt
Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(12):E715-24.
2012: Baohai Shao; Subramaniam Pennathur; Jay W Heinecke
Myeloperoxidase targets apolipoprotein A-I, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions.
The Journal of biological chemistry 2012;287(9):6375-86.
2012: Husam M Abu-Soud; Peter R Andreana; Jashoman Banerjee; Jaeman Byun; Michael Diamond; Dhiman Maitra; Ghassan M Saed; Carlos Souza; Subramaniam Pennathur
The reaction of HOCl and cyanocobalamin: corrin destruction and the liberation of cyanogen chloride.
Free radical biology & medicine 2012;52(3):616-25.
2012: Bing Pan; Subramaniam Pennathur; Hui Ren; Jonathan D Smith; Yuhui Wang; Yongyu Wang; Baoqi Yu; Y Eugene Chen; Yubin He; Liang Ji; Donghui Liu; George Liu; Xiaofeng Lv; Yijing Ma; Lemin Zheng
Diabetic HDL is dysfunctional in stimulating endothelial cell migration and proliferation due to down regulation of SR-BI expression.
PloS one 2012;7(11):e48530.
2011: Lan Dai; Xing Fan; Jintang He; Yashu Liu; Subramaniam Pennathur; Anuradha Vivekanandan; Jaeman Byun; David M Lubman
Dose-dependent proteomic analysis of glioblastoma cancer stem cells upon treatment with γ-secretase inhibitor.
Proteomics 2011;11(23):4529-40.
2011: Donghui Liu; Bing Pan; Subramaniam Pennathur; Xunliang Tong; Youyi Zhang; Y Eugene Chen; Jing-Yan Han; Yining Huang; Liang Ji; Lemin Zheng
Human apolipoprotein A-I induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through ATP-binding cassette transporter A1.
American journal of physiology. Cell physiology 2011;301(3):C739-48.
2011: Savitha Subramanian; Shari Wang; Matthew M Yeh; Lixia Zeng; Leela Goodspeed; W Geoffrey Haigh; George N Ioannou; Jinkyu Kim; Kris V Kowdley; Kevin D O'Brien; Subramaniam Pennathur; Alan Chait
Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice.
Journal of lipid research 2011;52(9):1626-35.
2011: Dhiman Maitra; Subramaniam Pennathur; Ghassan M Saed; Ibrahim Abdulhamid; Peter R Andreana; Jaeman Byun; Michael Diamond; Husam M Abu-Soud
Reaction of hemoglobin with HOCl: mechanism of heme destruction and free iron release.
Free radical biology & medicine 2011;51(2):374-86.
2011: Dhiman Maitra; Subramaniam Pennathur; Ghassan M Saed; Ibrahim Abdulhamid; Peter R Andreana; Jaeman Byun; Michael Diamond; Husam M Abu-Soud
Mechanism of hypochlorous acid-mediated heme destruction and free iron release.
Free radical biology & medicine 2011;51(2):364-73.
2011: Michael Miller; Subramaniam Pennathur; Neil J Stone; Christie Ballantyne; Vera Bittner; Michael H Criqui; Henry N Ginsberg; Anne Carol Goldberg; William James Howard; Marc S Jacobson; Penny M Kris-Etherton; Terry A Lennie; Moshe Levi; Theodore Mazzone
Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association.
Circulation 2011;123(20):2292-333.
2011: Deidre L Golej; Bardia Askari; Farah Kramer; Shelley Barnhart; Anuradha Vivekanandan-Giri; Subramaniam Pennathur; Karin E Bornfeldt
Long-chain acyl-CoA synthetase 4 modulates prostaglandin E₂ release from human arterial smooth muscle cells.
Journal of lipid research 2011;52(4):782-93.
2011: Matthew Sparks; Kelly K Parsons; Johannes Stegbauer; Susan B Gurley; Anuradha Vivekanandan-Giri; Christopher N Fortner; Jay Snouwaert; Eric W Raasch; Robert C Griffiths; Timothy A J Haystead; Thu H Le; Subramaniam Pennathur; Beverly Koller; Thomas M Coffman
Angiotensin II type 1A receptors in vascular smooth muscle cells do not influence aortic remodeling in hypertension.
Hypertension 2011;57(3):577-85.
2011: Carlos Souza; Michael Diamond; Dhiman Maitra; Arlindo A Moura; Subramaniam Pennathur; Ghassan M Saed; Husam M Abu-Soud
Hypochlorous acid-induced heme degradation from lactoperoxidase as a novel mechanism of free iron release and tissue injury in inflammatory diseases.
PloS one 2011;6(11):e27641.
2011: Anuradha Vivekanandan-Giri; Rodica Pop-Busui; Jessica L Slocum; venkatesha basrur; Carolyn L Buller; Wenjun Ju; Matthias Kretzler; David M Lubman; Subramaniam Pennathur
Urine glycoprotein profile reveals novel markers for chronic kidney disease.
International journal of proteomics 2011;2011():214715.
2011: Nagireddy Putluri; Vasanta Putluri; Theodore R Sana; Ali Shojaie; Jeman Byun; Chad J Creighton; Steven M Fischer; George Michailidis; Srilatha Nalluri; Ganesh S Palapattu; Subramaniam Pennathur; Shaiju K Vareed; Vihas T Vasu; Anuradha Vivekanandan-Giri; Arun Sreekumar
Metabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells.
PloS one 2011;6(7):e21417.
2011: Anuradha Vivekanandan-Giri; Jaeman Byun; Subramaniam Pennathur
Quantitative analysis of amino Acid oxidation markers by tandem mass spectrometry.
Methods in enzymology 2011;491():73-89.
2010: Jeffrey H Wang; Jaeman Byun; Subramaniam Pennathur
Analytical approaches to metabolomics and applications to systems biology.
Seminars in nephrology 2010;30(5):500-11.
2010: Arun Sreekumar; Laila M Poisson; Thekkelnaycke Rajendiran; Amjad P Khan; Qi Cao; Jindan YU; Bharathi Laxman; Rohit Mehra; Robert J Lonigro; Yong Li; Mukesh K Nyati; Aarif Ahsan; Shanker Kalyana-Sundaram; Bo Han; Xuhong Cao; Jaeman Byun; Gilbert S Omenn; Debashis Ghoshd; Subramaniam Pennathur; Danny C Alexander; Alvin Berger; Jeffrey R Shuster; John T Wei; Sooryanarayana Lnu; Christopher W Beecher; Arul M Chinnaiyan
Re: Florian Jentzmik, Carsten Stephan, Kurt Miller, et al. Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours. Eur Urol 2010;58:12-8.
European urology 2010;58(3):e29-30; author reply e31-2.
2010: Subramaniam Pennathur; Dhiman Maitra; Jaeman Byun; Inga Sliskovic; Ibrahim Abdulhamid; Ghassan M Saed; Michael Diamond; Husam M Abu-Soud
Potent antioxidative activity of lycopene: A potential role in scavenging hypochlorous acid.
Free radical biology & medicine 2010;49(2):205-13.
2010: Baohai Shao; Subramaniam Pennathur; Ioanna Pagani; Michael N Oda; Joseph L Witztum; John F Oram; Jay W Heinecke
Modifying apolipoprotein A-I by malondialdehyde, but not by an array of other reactive carbonyls, blocks cholesterol efflux by the ABCA1 pathway.
The Journal of biological chemistry 2010;285(24):18473-84.
2010: Rodica Pop-Busui; Laurel Roberts; Subramaniam Pennathur; Matthias Kretzler; Frank C Brosius III; Eva L Feldman
The management of diabetic neuropathy in CKD.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2010;55(2):365-85.
2009: Andrea M Vincent; John M Hayes; Lisa L McLean; Anuradha Vivekanandan-Giri; Subramaniam Pennathur; Eva L Feldman
Dyslipidemia-induced neuropathy in mice: the role of oxLDL/LOX-1.
Diabetes 2009;58(10):2376-85.
2009: Louise Hecker; Ragini Vittal; Tamara Jones; Rajesh Jagirdar; Tracy R Luckhardt; Jeffrey C Horowitz; Subramaniam Pennathur; Fernando J Martinez; Victor J Thannickal
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury.
Nature medicine 2009;15(9):1077-81.
2009: Liming Shu; James L Park; Jaeman Byun; Subramaniam Pennathur; Jessica Kollmeyer; James A Shayman
Decreased nitric oxide bioavailability in a mouse model of Fabry disease.
Journal of the American Society of Nephrology : JASN 2009;20(9):1975-85.
2009: Wenpu Zhao; Seth G Thacker; Jeffrey B Hodgin; Hongyu Zhang; Jeffrey H Wang; James L Park; Ann Randolph; Emily Somers; Subramaniam Pennathur; Matthias Kretzler; Frank C Brosius III; Mariana J Kaplan
The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2729-40.
2009: Sung Hoon Back; Donalyn Scheuner; Jaeseok Han; Benbo Song; Mark Ribick; Junying Wang; Robert D Gildersleeve; Subramaniam Pennathur; Randal J Kaufman
Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells.
Cell metabolism 2009;10(1):13-26.
2009: Rodica Pop-Busui; Elif Arioglu Oral; David M Raffel; Jaeman Byun; Valida Bajirovic; Anuradha Vivekanandan-Giri; Aaron Kellogg; Subramaniam Pennathur; Martin J Stevens
Impact of rosiglitazone and glyburide on nitrosative stress and myocardial blood flow regulation in type 2 diabetes mellitus.
Metabolism: clinical and experimental 2009;58(7):989-94.
2009: Shun Feng; Na Yang; Subramaniam Pennathur; Steve Goodison; David M Lubman
Enrichment of glycoproteins using nanoscale chelating concanavalin A monolithic capillary chromatography.
Analytical chemistry 2009;81(10):3776-83.
2009: Kelly A Posey; Deborah J Clegg; Richard L Printz; Jaeman Byun; Gregory J Morton; Anuradha Vivekanandan-Giri; Subramaniam Pennathur; Denis Baskin; Jay W Heinecke; Stephen C Woods; Michael W Schwartz; Kevin D Niswender
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet.
American journal of physiology. Endocrinology and metabolism 2009;296(5):E1003-12.
2009: Daryl M Okamura; Subramaniam Pennathur; Katie Pasichnyk; Jesús M López-Guisa; Sarah Collins; Maria Febbraio; Jay Heinecke; Allison A Eddy
CD36 regulates oxidative stress and inflammation in hypercholesterolemic CKD.
Journal of the American Society of Nephrology : JASN 2009;20(3):495-505.
2009: Arun Sreekumar; Laila M Poisson; Thekkelnaycke Rajendiran; Amjad P Khan; Qi Cao; Jindan YU; Bharathi Laxman; Rohit Mehra; Robert J Lonigro; Yong Li; Mukesh K Nyati; Aarif Ahsan; Shanker Kalyana-Sundaram; Bo Han; Xuhong Cao; Jaeman Byun; Gilbert S Omenn; Debashis Ghosh; Subramaniam Pennathur; Danny C Alexander; Alvin Berger; Jeffrey R Shuster; John T Wei; Sooryanarayana Lnu; Christopher W Beecher; Arul M Chinnaiyan
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.
Nature 2009;457(7231):910-4.
2008: Anuradha Vivekanadan-Giri; Jeffrey H Wang; Jaeman Byun; Subramaniam Pennathur
Mass spectrometric quantification of amino acid oxidation products identifies oxidative mechanisms of diabetic end-organ damage.
Reviews in endocrine & metabolic disorders 2008;9(4):275-87.
2008: Jyoti D Malhotra; Hongzhi Miao; Kezhong Zhang; Anna Wolfson; Subramaniam Pennathur; Steven W Pipe; Randal J Kaufman
Antioxidants reduce endoplasmic reticulum stress and improve protein secretion.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(47):18525-30.
2008: Benbo Song; Donalyn Scheuner; David Ron; Subramaniam Pennathur; Randal J Kaufman
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes.
The Journal of clinical investigation 2008;118(10):3378-89.
2008: Hongyu Zhang; Jharna Saha; Jaeman Byun; MaryLee Schin; Matthew Lorenz; Robert T Kennedy ; Matthias Kretzler; Eva L Feldman; Subramaniam Pennathur; Frank C Brosius III
Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy.
American journal of physiology. Renal physiology 2008;295(4):F1071-81.
2008: Timothy D Wiggin; Matthias Kretzler; Subramaniam Pennathur; Kelli A Sullivan; Frank C Brosius III; Eva L Feldman
Rosiglitazone treatment reduces diabetic neuropathy in streptozotocin-treated DBA/2J mice.
Endocrinology 2008;149(10):4928-37.
2008: Pattie Green; Tomas Vaisar; Subramaniam Pennathur; J Jacob Kulstad; Andrew B Moore; Santica Marcovina; John D Brunzell; Robert H Knopp; Xue-Qiao Zhao; Jay W Heinecke
Combined statin and niacin therapy remodels the high-density lipoprotein proteome.
Circulation 2008;118(12):1259-67.
2008: Ying Qian; Eva L Feldman; Subramaniam Pennathur; Matthias Kretzler; Frank C Brosius III
From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathy.
Diabetes 2008;57(6):1439-45.
2007: Subramaniam Pennathur; Jay W Heinecke
Oxidative stress and endothelial dysfunction in vascular disease.
Current diabetes reports 2007;7(4):257-64.
2007: Subramaniam Pennathur; Jay W Heinecke
Mechanisms for oxidative stress in diabetic cardiovascular disease.
Antioxidants & redox signaling 2007;9(7):955-69.
2007: Tomas Vaisar; Subramaniam Pennathur; Pattie Green; Sina A Gharib; Andrew N Hoofnagle; Marian C Cheung; Jaeman Byun; Simona Vuletic; Sean Y Kassim; Pragya Singh; Helen Chea; Robert H Knopp; John D Brunzell; Randolph L Geary; Alan Chait; Xue-Qiao Zhao; Keith B Elkon; Santica Marcovina; Paul Ridker; John F Oram; Jay W Heinecke
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL.
The Journal of clinical investigation 2007;117(3):746-56.
2006: Frank C Brosius III; Thomas H Hostetter; Ellie Kelepouris; Mark M Mitsnefes; Sharon M Moe; Michael A Moore; Subramaniam Pennathur; Grace L Smith; Peter W F Wilson
Detection of chronic kidney disease in patients with or at increased risk of cardiovascular disease: a science advisory from the American Heart Association Kidney and Cardiovascular Disease Council; the Councils on High Blood Pressure Research, Cardiovascular Disease in the Young, and Epidemiology and Prevention; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: Developed in Collaboration With the National Kidney Foundation.
Hypertension 2006;48(4):751-5.
2006: Frank C Brosius III; Thomas H Hostetter; Ellie Kelepouris; Mark M Mitsnefes; Sharon M Moe; Michael A Moore; Subramaniam Pennathur; Grace L Smith; Peter W F Wilson
Detection of chronic kidney disease in patients with or at increased risk of cardiovascular disease: a science advisory from the American Heart Association Kidney And Cardiovascular Disease Council; the Councils on High Blood Pressure Research, Cardiovascular Disease in the Young, and Epidemiology and Prevention; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: developed in collaboration with the National Kidney Foundation.
Circulation 2006;114(10):1083-7.
2006: Hande Gurer-Orhan; Nuran Ercal; Suneetha Mare; Subramaniam Pennathur; Hilmi Orhan; Jay W Heinecke
Misincorporation of free m-tyrosine into cellular proteins: a potential cytotoxic mechanism for oxidized amino acids.
The Biochemical journal 2006;395(2):277-84.
2006: Junko Takeshita; Jaeman Byun; Thomas Q Nhan; David K Pritchard; Subramaniam Pennathur; Steven M Schwartz; Alan Chait; Jay W Heinecke
Myeloperoxidase generates 5-chlorouracil in human atherosclerotic tissue: a potential pathway for somatic mutagenesis by macrophages.
The Journal of biological chemistry 2006;281(6):3096-104.
2005: Dong-Kug Choi; Subramaniam Pennathur; Celine Perier; Kim Tieu; Peter Teismann; Du-Chu Wu; Vernice Jackson-Lewis; Miquel Vila; Jean-Paul Vonsattel; Jay W Heinecke; Serge Przedborski
Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(28):6594-600.
2005: Subramaniam Pennathur; Yasuo Ido; Jozsef I Heller; Jaeman Byun; Ratna Danda; Pablo Pergola; Joseph R Williamson; Jay W Heinecke
Reactive carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species: a potential pathway for oxidative damage of retinal proteins in diabetes.
The Journal of biological chemistry 2005;280(24):22706-14.
2004: Najib Lamharzi; Catherine B Renard; Farah Kramer; Subramaniam Pennathur; Jay W Heinecke; Alan Chait; Karin E Bornfeldt
Hyperlipidemia in concert with hyperglycemia stimulates the proliferation of macrophages in atherosclerotic lesions: potential role of glucose-oxidized LDL.
Diabetes 2004;53(12):3217-25.
2004: Subramaniam Pennathur; Constanze Bergt; Baohai Shao; Jaeman Byun; Sean Y Kassim; Pragya Singh; Pattie Green; Thomas O McDonald; John D Brunzell; Alan Chait; John F Oram; Kevin O'brien; Randolph L Geary; Jay W Heinecke
Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species.
The Journal of biological chemistry 2004;279(41):42977-83.
2004: Constanze Bergt; Subramaniam Pennathur; Xiaoyun Fu; Jaeman Byun; Kevin O'Brien; Thomas O McDonald; Pragya Singh; Gm Anantharamaiah; Alan Chait; John D Brunzell; Randolph L Geary; John F Oram; Jay W Heinecke
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(35):13032-7.
2004: Subramaniam Pennathur; Jay W Heinecke
Mechanisms of oxidative stress in diabetes: implications for the pathogenesis of vascular disease and antioxidant therapy.
Frontiers in bioscience : a journal and virtual library 2004;9():565-74.
2001: S Bhattacharjee; Subramaniam Pennathur; Jaeman Byun; J Crowley; D Mueller; J Gischler; R S Hotchkiss; Jay W Heinecke
NADPH oxidase of neutrophils elevates o,o'-dityrosine cross-links in proteins and urine during inflammation.
Archives of biochemistry and biophysics 2001;395(1):69-77.
2001: Subramaniam Pennathur; J D Wagner; C Leeuwenburgh; K N Litwak; Jay W Heinecke
A hydroxyl radical-like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease.
The Journal of clinical investigation 2001;107(7):853-60.
2000: J I Heller; JR Crowley; Stanley L Hazen; D M Salvay; P Wagner; Subramaniam Pennathur; Jay W Heinecke
p-hydroxyphenylacetaldehyde, an aldehyde generated by myeloperoxidase, modifies phospholipid amino groups of low density lipoprotein in human atherosclerotic intima.
The Journal of biological chemistry 2000;275(14):9957-62.
1999: Subramaniam Pennathur; Vernice Jackson-Lewis; Serge Przedborski; Jay W Heinecke
Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.
The Journal of biological chemistry 1999;274(49):34621-8.
1999: Patricia Polacino; V Stallard; J E Klaniecki; Subramaniam Pennathur; David C Montefiori; A J Langlois; Barbra A Richardson; William R Morton; Raoul E Benveniste; Shiu-Lok Hu
Role of immune responses against the envelope and the core antigens of simian immunodeficiency virus SIVmne in protection against homologous cloned and uncloned virus challenge in Macaques.
Journal of virology 1999;73(10):8201-15.
1997: C Leeuwenburgh; J E Rasmussen; Fong-Fu Hsu; Dianne M Mueller; Subramaniam Pennathur; Jay W Heinecke
Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques.
The Journal of biological chemistry 1997;272(6):3520-6.
1993: Subramaniam Pennathur; L D Madison; T W Kay; J Larry Jameson
Localization of promoter sequences required for thyrotropin-releasing hormone and thyroid hormone responsiveness of the glycoprotein hormone alpha-gene in primary cultures of rat pituitary cells.
Molecular endocrinology (Baltimore, Md.) 1993;7(6):797-805.