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Merja Penttilä

Research Profile

Living Beings

Chemicals & Drugs

Concepts & Ideas

Genes & Molecular Sequences

Physiology

Gene Expression Regulation, Fungal

Procedures

Cloning, Molecular

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Publications

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Mervi H Toivari; Maija-Leena Vehkomäki; Yvonne Nygård; Merja Penttilä; Laura Ruohonen; Marilyn G Wiebe
Low pH D-xylonate production with Pichia kudriavzevii.
Maija Tenkanen; Mária Vršanská; Dominic W Wong; Merja Penttilä; Vladimír Puchart; Markku Saloheimo; Matti Siika-Aho; Peter Biely
Xylanase XYN IV from Trichoderma reesei showing exo- and endo-xylanase activity.
Joosu Kuivanen; Dominik Mojzita; Merja Penttilä; Peter Richard; Yanming Wang; Satu Hilditch; Marilyn G Wiebe
Engineering filamentous fungi for conversion of D-galacturonic acid to L-galactonic acid.

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All Publications

2013: Mervi H Toivari; Maija-Leena Vehkomäki; Yvonne Nygård; Merja Penttilä; Laura Ruohonen; Marilyn G Wiebe
Low pH D-xylonate production with Pichia kudriavzevii.
Bioresource technology 2013;133():555-62.
2013: Maija Tenkanen; Mária Vršanská; Dominic W Wong; Merja Penttilä; Vladimír Puchart; Markku Saloheimo; Matti Siika-Aho; Peter Biely
Xylanase XYN IV from Trichoderma reesei showing exo- and endo-xylanase activity.
The FEBS journal 2013;280(1):285-301.
2012: Joosu Kuivanen; Dominik Mojzita; Merja Penttilä; Peter Richard; Yanming Wang; Satu Hilditch; Marilyn G Wiebe
Engineering filamentous fungi for conversion of D-galacturonic acid to L-galactonic acid.
Applied and environmental microbiology 2012;78(24):8676-83.
2012: Mervi H Toivari; Yvonne Nygård; Merja Penttilä; Laura Ruohonen; Marilyn G Wiebe
Microbial D-xylonate production.
Applied microbiology and biotechnology 2012;96(1):1-8.
2012: Orquídea Ribeiro; Lucília Domingues; Merja Penttilä; Marilyn G Wiebe
Nutritional requirements and strain heterogeneity in Ashbya gossypii.
Journal of basic microbiology 2012;52(5):582-9.
2012: Paula Jouhten; Marilyn Wiebe; Merja Penttilä
Dynamic flux balance analysis of the metabolism of Saccharomyces cerevisiae during the shift from fully respirative or respirofermentative metabolic states to anaerobiosis.
The FEBS journal 2012;279(18):3338-54.
2012: Mervi H Toivari; Mari Valkonen; Maija-Leena Vehkomäki; Martina Andberg; Mojca Benčina; Anu Koivula; Esa-Pekka Kumpula; Hannu Maaheimo; Yvonne Nygård; Merja Penttilä; Laura Ruohonen; Marilyn G Wiebe
Metabolic engineering of Saccharomyces cerevisiae for bioconversion of D-xylose to D-xylonate.
Metabolic engineering 2012;14(4):427-36.
2012: Outi M Koivistoinen; Merja Penttilä; Peter Richard; Laura Ruohonen; Dominik Mojzita
Sorbitol dehydrogenase of Aspergillus niger, SdhA, is part of the oxido-reductive D-galactose pathway and essential for D-sorbitol catabolism.
FEBS letters 2012;586(4):378-83.
2012: Dominik Mojzita; Merja Penttilä; Outi M Koivistoinen; Hannu Maaheimo; Laura Ruohonen; Peter Richard
Identification of the galactitol dehydrogenase, LadB, that is part of the oxido-reductive D-galactose catabolic pathway in Aspergillus niger.
Fungal genetics and biology : FG & B 2012;49(2):152-9.
2012: Mari Häkkinen; Merja Oja; Nina Aro; Mikko Arvas; Merja Penttilä; Markku Saloheimo; Tiina Pakula
Re-annotation of the CAZy genes of Trichoderma reesei and transcription in the presence of lignocellulosic substrates.
Microbial cell factories 2012;11():134.
2011: Yvonne Nygård; Merja Penttilä; Laura Ruohonen; Mervi H Toivari; Marilyn G Wiebe
Bioconversion of d-xylose to d-xylonate with Kluyveromyces lactis.
Metabolic engineering 2011;13(4):383-91.
2011: Ritva Verho; Merja Penttilä; Peter Richard
Cloning of two genes (LAT1,2) encoding specific L: -arabinose transporters of the L: -arabinose fermenting yeast Ambrosiozyma monospora.
Applied biochemistry and biotechnology 2011;164(5):604-11.
2011: Mikko Arvas; Paula Jouhten; Heini Koivistoinen; Erno Lindfors; Tiina Pakula; Merja Penttilä; Jari J Rautio; Bart Smit; Marilyn Wiebe; Markku Saloheimo
Correlation of gene expression and protein production rate - a system wide study.
BMC genomics 2011;12():616.
2011: Marja Ilmén; Anu Koivula; Daniël C la Grange; John McBride; Mark Mellon; Simon Ahlgren; Elena Brevnova; Kristen Deleault; Riaan Den Haan; Allan Froehlich; Vineet Rajgarhia; Matti Siika-Aho; Naomi Thorngren; Willem H van Zyl; Sanni P Voutilainen; Erin Wiswall; Merja Penttilä
High level secretion of cellobiohydrolases by Saccharomyces cerevisiae.
Biotechnology for biofuels 2011;4():30.
2011: Matthias G Steiger; Marika Vitikainen; Pekka Uskonen; Kurt Brunner; Gerhard Adam; Tiina Pakula; Merja Penttilä; Markku Saloheimo; Robert L Mach; Astrid R Mach-Aigner
Transformation system for Hypocrea jecorina (Trichoderma reesei) that favors homologous integration and employs reusable bidirectionally selectable markers.
Applied and environmental microbiology 2011;77(1):114-21.
2010: Mikko Arvas; Niina Haiminen; Bart Smit; Jari J Rautio; Marika Vitikainen; Marilyn Wiebe; Diego Martinez; Christine Chee; Joe Kunkel; Charles Sanchez; Mary Anne Nelson; Tiina Pakula; Markku Saloheimo; Merja Penttilä; Teemu Kivioja
Detecting novel genes with sparse arrays.
Gene 2010;467(1-2):41-51.
2010: Mervi H Toivari; Laura Ruohonen; Peter Richard; Merja Penttilä; Marilyn G Wiebe
Saccharomyces cerevisiae engineered to produce D-xylonate.
Applied microbiology and biotechnology 2010;88(3):751-60.
2010: Dominik Mojzita; Kiira Vuoristo; Outi M Koivistoinen; Merja Penttilä; Peter Richard
The 'true' L-xylulose reductase of filamentous fungi identified in Aspergillus niger.
FEBS letters 2010;584(16):3540-4.
2010: Dominik Mojzita; Merja Penttilä; Peter Richard
Identification of an L-arabinose reductase gene in Aspergillus niger and its role in L-arabinose catabolism.
The Journal of biological chemistry 2010;285(31):23622-8.
2010: Orquídea Ribeiro; Marilyn Wiebe; Marja Ilmén; Lucília Domingues; Merja Penttilä
Expression of Trichoderma reesei cellulases CBHI and EGI in Ashbya gossypii.
Applied microbiology and biotechnology 2010;87(4):1437-46.
2010: Harry Boer; Hannu Maaheimo; Anu Koivula; Merja Penttilä; Peter Richard
Identification in Agrobacterium tumefaciens of the D-galacturonic acid dehydrogenase gene.
Applied microbiology and biotechnology 2010;86(3):901-9.
2010: Marilyn G Wiebe; Dominik Mojzita; Satu Hilditch; Laura Ruohonen; Merja Penttilä
Bioconversion of D-galacturonate to keto-deoxy-L-galactonate (3-deoxy-L-threo-hex-2-ulosonate) using filamentous fungi.
BMC biotechnology 2010;10():63.
2010: Dominik Mojzita; Marilyn Wiebe; Satu Hilditch; Harry Boer; Merja Penttilä; Peter Richard
Metabolic engineering of fungal strains for conversion of D-galacturonate to meso-galactarate.
Applied and environmental microbiology 2010;76(1):169-75.
2010: Mervi H Toivari; Hannu Maaheimo; Merja Penttilä; Laura Ruohonen
Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol.
Applied microbiology and biotechnology 2010;85(3):731-9.
2009: Tiina Nakari-Setälä; Marja Paloheimo; Jarno Kallio; Jari Vehmaanperä; Merja Penttilä; Markku Saloheimo
Genetic modification of carbon catabolite repression in Trichoderma reesei for improved protein production.
Applied and environmental microbiology 2009;75(14):4853-60.
2008: Astrid R Stricker; Peter Trefflinger; Nina Aro; Merja Penttilä; Robert L Mach
Role of Ace2 (Activator of Cellulases 2) within the xyn2 transcriptosome of Hypocrea jecorina.
Fungal genetics and biology : FG & B 2008;45(4):436-45.
2008: Marilyn G Wiebe; Eija Rintala; Anu Tamminen; Helena Simolin; Laura Salusjärvi; Mervi Toivari; Juha T Kokkonen; Jari Kiuru; Raimo A Ketola; Paula Jouhten; Anne Huuskonen; Hannu Maaheimo; Laura Ruohonen; Merja Penttilä
Central carbon metabolism of Saccharomyces cerevisiae in anaerobic, oxygen-limited and fully aerobic steady-state conditions and following a shift to anaerobic conditions.
FEMS yeast research 2008;8(1):140-54.
2008: Laura Salusjärvi; Matti Kankainen; Rabah Soliymani; Juha-Pekka Pitkänen; Merja Penttilä; Laura Ruohonen
Regulation of xylose metabolism in recombinant Saccharomyces cerevisiae.
Microbial cell factories 2008;7():18.
2008: Eija Rintala; Marilyn G Wiebe; Anu Tamminen; Laura Ruohonen; Merja Penttilä
Transcription of hexose transporters of Saccharomyces cerevisiae is affected by change in oxygen provision.
BMC microbiology 2008;8():53.
2007: Satu Hilditch; Suvi Berghäll; Nisse Kalkkinen; Merja Penttilä; Peter Richard
The missing link in the fungal D-galacturonate pathway: identification of the L-threo-3-deoxy-hexulosonate aldolase.
The Journal of biological chemistry 2007;282(36):26195-201.
2007: Mervi H Toivari; Laura Ruohonen; Andrei N Miasnikov; Peter Richard; Merja Penttilä
Metabolic engineering of Saccharomyces cerevisiae for conversion of D-glucose to xylitol and other five-carbon sugars and sugar alcohols.
Applied and environmental microbiology 2007;73(17):5471-6.
2007: Mari Valkonen; Eric R Kalkman; Markku Saloheimo; Merja Penttilä; Nick D Read; Rory R Duncan
Spatially segregated SNARE protein interactions in living fungal cells.
The Journal of biological chemistry 2007;282(31):22775-85.
2007: Anu Saloheimo; Jenita Rauta; Oleh V Stasyk; Andriy A Sibirny; Merja Penttilä; Laura Ruohonen
Xylose transport studies with xylose-utilizing Saccharomyces cerevisiae strains expressing heterologous and homologous permeases.
Applied microbiology and biotechnology 2007;74(5):1041-52.
2007: Torsten Neuhof; Ralf Dieckmann; Irina S Druzhinina; Christian P Kubicek; Tiina Nakari-Setälä; Merja Penttilä; Hans von Döhren
Direct identification of hydrophobins and their processing in Trichoderma using intact-cell MALDI-TOF MS.
The FEBS journal 2007;274(3):841-52.
2007: Eija Rintala; Juha-Pekka Pitkänen; Maija-Leena Vehkomäki; Merja Penttilä; Laura Ruohonen
The ORF YNL274c (GOR1) codes for glyoxylate reductase in Saccharomyces cerevisiae.
Yeast (Chichester, England) 2007;24(2):129-36.
2007: Brigitte Gasser; Michael Maurer; Jari J Rautio; Michael Sauer; Anamitra Bhattacharyya; Markku Saloheimo; Merja Penttilä; Diethard Mattanovich
Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions.
BMC genomics 2007;8():179.
2007: Jari J Rautio; Michael Bailey; Teemu Kivioja; Hans Söderlund; Merja Penttilä; Markku Saloheimo
Physiological evaluation of the filamentous fungus Trichoderma reesei in production processes by marker gene expression analysis.
BMC biotechnology 2007;7():28.
2007: Marja Ilmén; Kari Koivuranta; Laura Ruohonen; Pirkko Suominen; Merja Penttilä
Efficient production of L-lactic acid from xylose by Pichia stipitis.
Applied and environmental microbiology 2007;73(1):117-23.
2006: Janis Liepins; Satu Kuorelahti; Merja Penttilä; Peter Richard
Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina.
The FEBS journal 2006;273(18):4229-35.
2006: Satu Kuorelahti; Paula Jouhten; Hannu Maaheimo; Merja Penttilä; Peter Richard
L-galactonate dehydratase is part of the fungal path for D-galacturonic acid catabolism.
Molecular microbiology 2006;61(4):1060-8.
2006: Jari J Rautio; Kari Kataja; Reetta M Satokari; Merja Penttilä; Hans Söderlund; Markku Saloheimo
Rapid and multiplexed transcript analysis of microbial cultures using capillary electophoresis-detectable oligonucleotide probe pools.
Journal of microbiological methods 2006;65(3):404-16.
2006: Sanna Askolin; Markus Linder; Karin Scholtmeijer; Maija Tenkanen; Merja Penttilä; Marcel L de Vocht; Han A B Wösten
Interaction and comparison of a class I hydrophobin from Schizophyllum commune and class II hydrophobins from Trichoderma reesei.
Biomacromolecules 2006;7(4):1295-301.
2006: Laura Salusjärvi; Juha-Pekka Pitkänen; Aristos Aristidou; Laura Ruohonen; Merja Penttilä
Transcription analysis of recombinant saccharomyces cerevisiae reveals novel responses to xylose.
Applied biochemistry and biotechnology 2006;128(3):237-61.
2006: Roman Rauscher; Elisabeth Würleitner; Christian Wacenovsky; Nina Aro; Astrid R Stricker; Susanne Zeilinger; Christian P Kubicek; Merja Penttilä; Robert L Mach
Transcriptional regulation of xyn1, encoding xylanase I, in Hypocrea jecorina.
Eukaryotic cell 2006;5(3):447-56.
2006: Jari J Rautio; Bart A Smit; Marilyn Wiebe; Merja Penttilä; Markku Saloheimo
Transcriptional monitoring of steady state and effects of anaerobic phases in chemostat cultures of the filamentous fungus Trichoderma reesei.
BMC genomics 2006;7():247.
2006: Mikko Arvas; Tiina Pakula; Karin Lanthaler; Markku Saloheimo; Mari Valkonen; Tapani Suortti; Geoff Robson; Merja Penttilä
Common features and interesting differences in transcriptional responses to secretion stress in the fungi Trichoderma reesei and Saccharomyces cerevisiae.
BMC genomics 2006;7():32.
2005: Sanna Askolin; Merja Penttilä; Han A B Wösten; Tiina Nakari-Setälä
The Trichoderma reesei hydrophobin genes hfb1 and hfb2 have diverse functions in fungal development.
FEMS microbiology letters 2005;253(2):281-8.
2005: Markus B Linder; Géza R Szilvay; Tiina Nakari-Setälä; Merja Penttilä
Hydrophobins: the protein-amphiphiles of filamentous fungi.
FEMS microbiology reviews 2005;29(5):877-96.
2005: Nina Aro; Tiina Pakula; Merja Penttilä
Transcriptional regulation of plant cell wall degradation by filamentous fungi.
FEMS microbiology reviews 2005;29(4):719-39.
2005: Satu Kuorelahti; Nisse Kalkkinen; Merja Penttilä; john londesborough; Peter Richard
Identification in the mold Hypocrea jecorina of the first fungal D-galacturonic acid reductase.
Biochemistry 2005;44(33):11234-40.
2005: Steven Geysens; Tiina Pakula; Jaana Uusitalo; Isabelle Dewerte; Merja Penttilä; Roland Contreras
Cloning and characterization of the glucosidase II alpha subunit gene of Trichoderma reesei: a frameshift mutation results in the aberrant glycosylation profile of the hypercellulolytic strain Rut-C30.
Applied and environmental microbiology 2005;71(6):2910-24.
2005: Teemu Kivioja; Mikko Arvas; Markku Saloheimo; Merja Penttilä; Esko Ukkonen
Optimization of cDNA-AFLP experiments using genomic sequence data.
Bioinformatics (Oxford, England) 2005;21(11):2573-9.
2005: Juha-Pekka Pitkänen; Eija Rintala; Aristos Aristidou; Laura Ruohonen; Merja Penttilä
Xylose chemostat isolates of Saccharomyces cerevisiae show altered metabolite and enzyme levels compared with xylose, glucose, and ethanol metabolism of the original strain.
Applied microbiology and biotechnology 2005;67(6):827-37.
2005: Anna Collén; Markku Saloheimo; Michael Bailey; Merja Penttilä; Tiina Pakula
Protein production and induction of the unfolded protein response in Trichoderma reesei strain Rut-C30 and its transformant expressing endoglucanase I with a hydrophobic tag.
Biotechnology and bioengineering 2005;89(3):335-44.
2005: Bernhard Seiboth; Lukas Hartl; Noora Salovuori; Karin Lanthaler; Geoff Robson; Jari Vehmaanperä; Merja Penttilä; Christian P Kubicek
Role of the bga1-encoded extracellular {beta}-galactosidase of Hypocrea jecorina in cellulase induction by lactose.
Applied and environmental microbiology 2005;71(2):851-7.
2005: Tiina Pakula; Katri Salonen; Jaana Uusitalo; Merja Penttilä
The effect of specific growth rate on protein synthesis and secretion in the filamentous fungus Trichoderma reesei.
Microbiology (Reading, England) 2005;151(Pt 1):135-43.
2004: Patrick Murray; Nina Aro; Catherine Collins; Alice Grassick; Merja Penttilä; Markku Saloheimo; Maria G Tuohy
Expression in Trichoderma reesei and characterisation of a thermostable family 3 beta-glucosidase from the moderately thermophilic fungus Talaromyces emersonii.
Protein expression and purification 2004;38(2):248-57.
2004: Mari Valkonen; Merja Penttilä; Markku Saloheimo
The ire1 and ptc2 genes involved in the unfolded protein response pathway in the filamentous fungus Trichoderma reesei.
Molecular genetics and genomics : MGG 2004;272(4):443-51.
2004: Sanna Askolin; Johan P Turkenburg; Maija Tenkanen; Sinikka Uotila; Keith S Wilson; Merja Penttilä; Kalevi Visuri
Purification, crystallization and preliminary X-ray diffraction analysis of the Trichoderma reesei hydrophobin HFBI.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 10):1903-5.
2004: Markus B Linder; Mingqiang Qiao; Frank Laumen; Klaus Selber; Teppo Hyytiä; Tiina Nakari-Setälä; Merja Penttilä
Efficient purification of recombinant proteins using hydrophobins as tags in surfactant-based two-phase systems.
Biochemistry 2004;43(37):11873-82.
2004: Hashem Al-Sheikh; Adrian J Watson; Georgina A Lacey; Peter J Punt; Donald A MacKenzie; David J Jeenes; Tiina Pakula; Merja Penttilä; Marcos J C Alcocer; David B Archer
Endoplasmic reticulum stress leads to the selective transcriptional downregulation of the glucoamylase gene in Aspergillus niger.
Molecular microbiology 2004;53(6):1731-42.
2004: Mervi H Toivari; Laura Salusjärvi; Laura Ruohonen; Merja Penttilä
Endogenous xylose pathway in Saccharomyces cerevisiae.
Applied and environmental microbiology 2004;70(6):3681-6.
2004: Ritva Verho; Mikko Putkonen; john londesborough; Merja Penttilä; Peter Richard
A novel NADH-linked l-xylulose reductase in the l-arabinose catabolic pathway of yeast.
The Journal of biological chemistry 2004;279(15):14746-51.
2004: Johanna Hakanpää; Arja Paananen; Sanna Askolin; Tiina Nakari-Setälä; Tarja Parkkinen; Merja Penttilä; Markus B Linder; Juha Rouvinen
Atomic resolution structure of the HFBII hydrophobin, a self-assembling amphiphile.
The Journal of biological chemistry 2004;279(1):534-9.
2004: Markku Saloheimo; Huaming Wang; Mari Valkonen; Tuija Vasara; Anne Huuskonen; Marjukka Riikonen; Tiina Pakula; Michael Ward; Merja Penttilä
Characterization of secretory genes ypt1/yptA and nsf1/nsfA from two filamentous fungi: induction of secretory pathway genes of Trichoderma reesei under secretion stress conditions.
Applied and environmental microbiology 2004;70(1):459-67.
2003: Mari Valkonen; Michael Ward; Huaming Wang; Merja Penttilä; Markku Saloheimo
Improvement of foreign-protein production in Aspergillus niger var. awamori by constitutive induction of the unfolded-protein response.
Applied and environmental microbiology 2003;69(12):6979-86.
2003: Tiina Pakula; Marjukka Laxell; Anne Huuskonen; Jaana Uusitalo; Markku Saloheimo; Merja Penttilä
The effects of drugs inhibiting protein secretion in the filamentous fungus Trichoderma reesei. Evidence for down-regulation of genes that encode secreted proteins in the stressed cells.
The Journal of biological chemistry 2003;278(45):45011-20.
2003: Ritva Verho; john londesborough; Merja Penttilä; Peter Richard
Engineering redox cofactor regeneration for improved pentose fermentation in Saccharomyces cerevisiae.
Applied and environmental microbiology 2003;69(10):5892-7.
2003: Arja Paananen; Elina Vuorimaa; Mika Torkkeli; Merja Penttilä; Martti Kauranen; Olli Ikkala; Helge Lemmetyinen; Ritva Serimaa; Markus B Linder
Structural hierarchy in molecular films of two class II hydrophobins.
Biochemistry 2003;42(18):5253-8.
2003: Peter Richard; Ritva Verho; Mikko Putkonen; john londesborough; Merja Penttilä
Production of ethanol from L-arabinose by Saccharomyces cerevisiae containing a fungal L-arabinose pathway.
FEMS yeast research 2003;3(2):185-9.
2003: Mari Valkonen; Merja Penttilä; Markku Saloheimo
Effects of inactivation and constitutive expression of the unfolded- protein response pathway on protein production in the yeast Saccharomyces cerevisiae.
Applied and environmental microbiology 2003;69(4):2065-72.
2003: Laura Salusjärvi; Marjo Poutanen; Juha-Pekka Pitkänen; Heini Koivistoinen; Aristos Aristidou; Nisse Kalkkinen; Laura Ruohonen; Merja Penttilä
Proteome analysis of recombinant xylose-fermenting Saccharomyces cerevisiae.
Yeast (Chichester, England) 2003;20(4):295-314.
2003: Markku Saloheimo; Mari Valkonen; Merja Penttilä
Activation mechanisms of the HAC1-mediated unfolded protein response in filamentous fungi.
Molecular microbiology 2003;47(4):1149-61.
2003: Juha-Pekka Pitkänen; Aristos Aristidou; Laura Salusjärvi; Laura Ruohonen; Merja Penttilä
Metabolic flux analysis of xylose metabolism in recombinant Saccharomyces cerevisiae using continuous culture.
Metabolic engineering 2003;5(1):16-31.
2003: Nina Aro; Marja Ilmén; Anu Saloheimo; Merja Penttilä
ACEI of Trichoderma reesei is a repressor of cellulase and xylanase expression.
Applied and environmental microbiology 2003;69(1):56-65.
2002: Ritva Verho; Peter Richard; Per Harald Jonson; Lena Sundqvist; john londesborough; Merja Penttilä
Identification of the first fungal NADP-GAPDH from Kluyveromyces lactis.
Biochemistry 2002;41(46):13833-8.
2002: Markku Saloheimo; Juha Kuja-Panula; Erkko Ylösmäki; Michael Ward; Merja Penttilä
Enzymatic properties and intracellular localization of the novel Trichoderma reesei beta-glucosidase BGLII (cel1A).
Applied and environmental microbiology 2002;68(9):4546-53.
2002: Markku Saloheimo; Marja Paloheimo; Satu Hakola; Jaakko Pere; Barbara Swanson; Eini Nyyssönen; Amit Bhatia; Michael Ward; Merja Penttilä
Swollenin, a Trichoderma reesei protein with sequence similarity to the plant expansins, exhibits disruption activity on cellulosic materials.
European journal of biochemistry / FEBS 2002;269(17):4202-11.
2002: Markus Linder; Géza R Szilvay; Tiina Nakari-Setälä; Hans Söderlund; Merja Penttilä
Surface adhesion of fusion proteins containing the hydrophobins HFBI and HFBII from Trichoderma reesei.
Protein science : a publication of the Protein Society 2002;11(9):2257-66.
2002: Tiina Nakari-Setälä; Joana Azeredo; Mariana Henriques; Rosário Oliveira; José Teixeira; Markus Linder; Merja Penttilä
Expression of a fungal hydrophobin in the Saccharomyces cerevisiae cell wall: effect on cell surface properties and immobilization.
Applied and environmental microbiology 2002;68(7):3385-91.
2002: Tuija Vasara; Sirkka Keränen; Merja Penttilä; Markku Saloheimo
Characterisation of two 14-3-3 genes from Trichoderma reesei: interactions with yeast secretory pathway components.
Biochimica et biophysica acta 2002;1590(1-3):27-40.
2002: Peter Richard; Mikko Putkonen; Ritva Väänänen; john londesborough; Merja Penttilä
The missing link in the fungal L-arabinose catabolic pathway, identification of the L-xylulose reductase gene.
Biochemistry 2002;41(20):6432-7.
2002: Anna Collén; Klaus Selber; Teppo Hyytiä; Josefine Persson; Tiina Nakari-Setlä; Michael Bailey; Richard Fagerström; Maria-Regina Kula; Merja Penttilä; Henrik Stålbrand; Folke Tjerneld
Primary recovery of a genetically engineered Trichoderma reesei endoglucanase I (Cel 7B) fusion protein in cloud point extraction systems.
Biotechnology and bioengineering 2002;78(4):385-94.
2002: M J Bailey; Sanna Askolin; N Hörhammer; Maija Tenkanen; Markus Linder; Merja Penttilä; Tiina Nakari-Setälä
Process technological effects of deletion and amplification of hydrophobins I and II in transformants of Trichoderma reesei.
Applied microbiology and biotechnology 2002;58(6):721-7.
2002: Anna Collén; Josefine Persson; Markus Linder; Tiina Nakari-Setälä; Merja Penttilä; Folke Tjerneld; Ulf Sivars
A novel two-step extraction method with detergent/polymer systems for primary recovery of the fusion protein endoglucanase I-hydrophobin I.
Biochimica et biophysica acta 2002;1569(1-3):139-50.
2002: Anna Collén; Merja Penttilä; Henrik Stålbrand; Folke Tjerneld; Andres Veide
Extraction of endoglucanase I (Ce17B) fusion proteins from Trichoderma reesei culture filtrate in a poly(ethylene glycol)-phosphate aqueous two-phase system.
Journal of chromatography. A 2002;943(1):55-62.
2002: Teemu Kivioja; Mikko Arvas; Kari Kataja; Merja Penttilä; Hans Söderlund; Esko Ukkonen
Assigning probes into a small number of pools separable by electrophoresis.
Bioinformatics (Oxford, England) 2002;18 Suppl 1():S199-206.
2001: Tuija Vasara; Laura Salusjärvi; M Raudaskoski; Sirkka Keränen; Merja Penttilä; Markku Saloheimo
Interactions of the Trichoderma reesei rho3 with the secretory pathway in yeast and T. reesei.
Molecular microbiology 2001;42(5):1349-61.
2001: Peter Richard; john londesborough; Mikko Putkonen; Nisse Kalkkinen; Merja Penttilä
Cloning and expression of a fungal L-arabinitol 4-dehydrogenase gene.
The Journal of biological chemistry 2001;276(44):40631-7.
2001: Tuija Vasara; Markku Saloheimo; Sirkka Keränen; Merja Penttilä
Trichoderma reesei rho3 a homologue of yeast RH03 suppresses the growth defect of yeast sec15-1 mutation.
Current genetics 2001;40(2):119-27.
2001: Mervi H Toivari; Aristos Aristidou; Laura Ruohonen; Merja Penttilä
Conversion of xylose to ethanol by recombinant Saccharomyces cerevisiae: importance of xylulokinase (XKS1) and oxygen availability.
Metabolic engineering 2001;3(3):236-49.
2001: Nina Aro; Anu Saloheimo; Marja Ilmén; Merja Penttilä
ACEII, a novel transcriptional activator involved in regulation of cellulase and xylanase genes of Trichoderma reesei.
The Journal of biological chemistry 2001;276(26):24309-14.
2001: Klaus Selber; Anna Collén; Teppo Hyytiä; Merja Penttilä; Folke Tjerneld; Maria-Regina Kula
Parameters influencing protein extraction for whole broths in detergent based aqueous two-phase systems.
Bioseparation 2001;10(4-5):229-36.
2001: Markus Linder; Klaus Selber; Tiina Nakari-Setälä; M Qiao; Maria-Regina Kula; Merja Penttilä
The hydrophobins HFBI and HFBII from Trichoderma reesei showing efficient interactions with nonionic surfactants in aqueous two-phase systems.
Biomacromolecules 2001;2(2):511-7.
2001: Marjo Poutanen; Laura Salusjärvi; Laura Ruohonen; Merja Penttilä; Nisse Kalkkinen
Use of matrix-assisted laser desorption/ionization time-of-flight mass mapping and nanospray liquid chromatography/electrospray ionization tandem mass spectrometry sequence tag analysis for high sensitivity identification of yeast proteins separated by two-dimensional gel electrophoresis.
Rapid communications in mass spectrometry : RCM 2001;15(18):1685-92.
2000: Peter Richard; Mervi H Toivari; Merja Penttilä
The role of xylulokinase in Saccharomyces cerevisiae xylulose catabolism.
FEMS microbiology letters 2000;190(1):39-43.
2000: Aristos Aristidou; Merja Penttilä
Metabolic engineering applications to renewable resource utilization.
Current opinion in biotechnology 2000;11(2):187-98.
2000: Anu Saloheimo; Nina Aro; Marja Ilmén; Merja Penttilä
Isolation of the ace1 gene encoding a Cys(2)-His(2) transcription factor involved in regulation of activity of the cellulase promoter cbh1 of Trichoderma reesei.
The Journal of biological chemistry 2000;275(8):5817-25.
2000: Marleen Maras; Nico Callewaert; Kathleen Piens; Marc Claeyssens; W Martinet; Sylviane Dewaele; H Contreras; Isabelle Dewerte; Merja Penttilä; Roland Contreras
Molecular cloning and enzymatic characterization of a Trichoderma reesei 1,2-alpha-D-mannosidase.
Journal of biotechnology 2000;77(2-3):255-63.
2000: E Sabini; H Schubert; Garib N Murshudov; Keith S Wilson; M Siika-Aho; Merja Penttilä
The three-dimensional structure of a Trichoderma reesei beta-mannanase from glycoside hydrolase family 5.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 1):3-13.
2000: Tiina Pakula; Jaana Uusitalo; Markku Saloheimo; K Salonen; R J Aarts; Merja Penttilä
Monitoring the kinetics of glycoprotein synthesis and secretion in the filamentous fungus Trichoderma reesei: cellobiohydrolase I (CBHI) as a model protein.
Microbiology (Reading, England) 2000;146 ( Pt 1)():223-32.
1999: Peter Richard; Mervi H Toivari; Merja Penttilä
Evidence that the gene YLR070c of Saccharomyces cerevisiae encodes a xylitol dehydrogenase.
FEBS letters 1999;457(1):135-8.
1999: Markku Saloheimo; M Lund; Merja Penttilä
The protein disulphide isomerase gene of the fungus Trichoderma reesei is induced by endoplasmic reticulum stress and regulated by the carbon source.
Molecular & general genetics : MGG 1999;262(1):35-45.
1999: A Teleman; Peter Richard; Mervi H Toivari; Merja Penttilä
Identification and quantitation of phosphorus metabolites in yeast neutral pH extracts by nuclear magnetic resonance spectroscopy.
Analytical biochemistry 1999;272(1):71-9.
1999: Marleen Maras; A De Bruyn; Wouter Vervecken; J Uusitalo; Merja Penttilä; Roger Busson; Piet Herdewijn; Roland Contreras
In vivo synthesis of complex N-glycans by expression of human N-acetylglucosaminyltransferase I in the filamentous fungus Trichoderma reesei.
FEBS letters 1999;452(3):365-70.
1999: E Sabini; Andrzej M Brzozowski; M Dauter; Gideon J Davies; Keith S Wilson; Marja Paloheimo; Pirkko Suominen; M Siika-Aho; Merja Penttilä
Crystallization and preliminary X-ray crystallographic analysis of a Trichoderma reesei beta-mannanase from glycoside hydrolase family 5.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 5):1058-60.
1997: Markku Saloheimo; Tiina Nakari-Setälä; Maija Tenkanen; Merja Penttilä
cDNA cloning of a Trichoderma reesei cellulase and demonstration of endoglucanase activity by expression in yeast.
European journal of biochemistry / FEBS 1997;249(2):584-91.
1997: Tiina Nakari-Setälä; Nina Aro; Marja Ilmén; Gaston Muñoz; N Kalkkinen; Merja Penttilä
Differential expression of the vegetative and spore-bound hydrophobins of Trichoderma reesei--cloning and characterization of the hfb2 gene.
European journal of biochemistry / FEBS 1997;248(2):415-23.
1997: Nigel J Belshaw; Satu Hakola; H Nevalainen; Merja Penttilä; Pirkko Suominen; David B Archer
Trichoderma reesei sequences that bind to the nuclear matrix enhance transformation frequency.
Molecular & general genetics : MGG 1997;256(1):18-27.
1997: Gaston Muñoz; Tiina Nakari-Setälä; Eduardo Agosin; Merja Penttilä
Hydrophobin gene srh1, expressed during sporulation of the biocontrol agent Trichoderma harzianum.
Current genetics 1997;32(3):225-30.
1997: Marja Ilmén; Anu Saloheimo; M L Onnela; Merja Penttilä
Regulation of cellulase gene expression in the filamentous fungus Trichoderma reesei.
Applied and environmental microbiology 1997;63(4):1298-306.
1996: Marja Ilmén; M L Onnela; S Klemsdal; Sirkka Keränen; Merja Penttilä
Functional analysis of the cellobiohydrolase I promoter of the filamentous fungus Trichoderma reesei.
Molecular & general genetics : MGG 1996;253(3):303-14.
1996: E Margolles-Clark; Maija Tenkanen; Tiina Nakari-Setälä; Merja Penttilä
Cloning of genes encoding alpha-L-arabinofuranosidase and beta-xylosidase from Trichoderma reesei by expression in Saccharomyces cerevisiae.
Applied and environmental microbiology 1996;62(10):3840-6.
1996: M L Onnela; Maija-Liisa Suihko; Merja Penttilä; Sirkka Keränen
Use of a modified alcohol dehydrogenase, ADH1, promoter in construction of diacetyl non-producing brewer's yeast.
Journal of biotechnology 1996;49(1-3):101-9.
1996: E Margolles-Clark; Maija Tenkanen; E Luonteri; Merja Penttilä
Three alpha-galactosidase genes of Trichoderma reesei cloned by expression in yeast.
European journal of biochemistry / FEBS 1996;240(1):104-11.
1996: Marja Ilmén; C Thrane; Merja Penttilä
The glucose repressor gene cre1 of Trichoderma: isolation and expression of a full-length and a truncated mutant form.
Molecular & general genetics : MGG 1996;251(4):451-60.
1996: E Margolles-Clark; Markku Saloheimo; Matti Siika-Aho; Merja Penttilä
The alpha-glucuronidase-encoding gene of Trichoderma reesei.
Gene 1996;172(1):171-2.
1996: E Margolles-Clark; C K Hayes; G E Harman; Merja Penttilä
Improved production of Trichoderma harzianum endochitinase by expression in Trichoderma reesei.
Applied and environmental microbiology 1996;62(6):2145-51.
1996: Bärbel Hahn-Hägerdal; J Hallborn; H Jeppsson; N Meinander; M Walfridsson; H Ojamo; Merja Penttilä; F K Zimmermann
Redox balances in recombinant Saccharomyces cerevisiae.
Annals of the New York Academy of Sciences 1996;782():286-96.
1996: E Margolles-Clark; Maija Tenkanen; Hans Söderlund; Merja Penttilä
Acetyl xylan esterase from Trichoderma reesei contains an active-site serine residue and a cellulose-binding domain.
European journal of biochemistry / FEBS 1996;237(3):553-60.
1996: Tiina Nakari-Setälä; N Aro; N Kalkkinen; E Alatalo; Merja Penttilä
Genetic and biochemical characterization of the Trichoderma reesei hydrophobin HFBI.
European journal of biochemistry / FEBS 1996;235(1-2):248-55.
1995: M Walfridsson; J Hallborn; Merja Penttilä; S Keränen; Bärbel Hahn-Hägerdal
Xylose-metabolizing Saccharomyces cerevisiae strains overexpressing the TKL1 and TAL1 genes encoding the pentose phosphate pathway enzymes transketolase and transaldolase.
Applied and environmental microbiology 1995;61(12):4184-90.
1995: Sirkka Keränen; Merja Penttilä
Production of recombinant proteins in the filamentous fungus Trichoderma reesei.
Current opinion in biotechnology 1995;6(5):534-7.
1995: Tiina Nakari-Setälä; Merja Penttilä
Production of Trichoderma reesei cellulases on glucose-containing media.
Applied and environmental microbiology 1995;61(10):3650-5.
1995: J Hallborn; M Walfridsson; Merja Penttilä; Sirkka Keränen; Bärbel Hahn-Hägerdal
A short-chain dehydrogenase gene from Pichia stipitis having D-arabinitol dehydrogenase activity.
Yeast (Chichester, England) 1995;11(9):839-47.
1995: H Stålbrand; A Saloheimo; J Vehmaanperä; Bernard Henrissat; Merja Penttilä
Cloning and expression in Saccharomyces cerevisiae of a Trichoderma reesei beta-mannanase gene containing a cellulose binding domain.
Applied and environmental microbiology 1995;61(3):1090-7.
1995: R R Dhanaraj; JE Pitts; PG Nugent; P Orprayoon; Jonathan B Cooper; Tom L Blundell; J Uusitalo; Merja Penttilä
Protein engineering of surface loops: preliminary X-ray analysis of the CHY155-165RHI mutant.
Advances in experimental medicine and biology 1995;362():95-9.
1994: J Hallborn; M F Gorwa; N Meinander; Merja Penttilä; Sirkka Keränen; Bärbel Hahn-Hägerdal
The influence of cosubstrate and aeration on xylitol formation by recombinant Saccharomyces cerevisiae expressing the XYL1 gene.
Applied microbiology and biotechnology 1994;42(2-3):326-33.
1994: A Saloheimo; Bernard Henrissat; A M Hoffrén; O Teleman; Merja Penttilä
A novel, small endoglucanase gene, egl5, from Trichoderma reesei isolated by expression in yeast.
Molecular microbiology 1994;13(2):219-28.
1994: J Watari; Y Takata; M Ogawa; H Sahara; S Koshino; M L Onnela; U Airaksinen; R Jaatinen; Merja Penttilä; Sirkka Keränen
Molecular cloning and analysis of the yeast flocculation gene FLO1.
Yeast (Chichester, England) 1994;10(2):211-25.
1993: T Nakari; E Alatalo; Merja Penttilä
Isolation of Trichoderma reesei genes highly expressed on glucose-containing media: characterization of the tef1 gene encoding translation elongation factor 1 alpha.
Gene 1993;136(1-2):313-8.
1993: M Srisodsuk; Tapani Reinikainen; Merja Penttilä; Tuula T Teeri
Role of the interdomain linker peptide of Trichoderma reesei cellobiohydrolase I in its interaction with crystalline cellulose.
The Journal of biological chemistry 1993;268(28):20756-61.
1993: B Persson; J Hallborn; M Walfridsson; Bärbel Hahn-Hägerdal; Sirkka Keränen; Merja Penttilä; H Jörnvall
Dual relationships of xylitol and alcohol dehydrogenases in families of two protein types.
FEBS letters 1993;324(1):9-14.
1993: E Nyyssönen; Merja Penttilä; A Harkki; A Saloheimo; J K Knowles; Sirkka Keränen
Efficient production of antibody fragments by the filamentous fungus Trichoderma reesei.
Bio/technology (Nature Publishing Company) 1993;11(5):591-5.
1993: K Blomqvist; M Nikkola; P Lehtovaara; Maija-Liisa Suihko; U Airaksinen; K B Stråby; J K Knowles; Merja Penttilä
Characterization of the genes of the 2,3-butanediol operons from Klebsiella terrigena and Enterobacter aerogenes.
Journal of bacteriology 1993;175(5):1392-404.
1993: JE Pitts; J M Uusitalo; D Mantafounis; PG Nugent; D D Quinn; P Orprayoon; Merja Penttilä
Expression and characterisation of chymosin pH optima mutants produced in Trichoderma reesei.
Journal of biotechnology 1993;28(1):69-83.
1993: M J Bailey; M Siika-aho; A Valkeajärvi; Merja Penttilä
Hydrolytic properties of two cellulases of Trichoderma reesei expressed in yeast.
Biotechnology and applied biochemistry 1993;17 ( Pt 1)():65-76.
1992: A L Mäntylä; K H Rossi; S A Vanhanen; Merja Penttilä; Pirkko Suominen; K M Nevalainen
Electrophoretic karyotyping of wild-type and mutant Trichoderma longibrachiatum (reesei) strains.
Current genetics 1992;21(6):471-7.
1992: Tuula T Teeri; Merja Penttilä; Sirkka Keränen; H Nevalainen; J K Knowles
Structure, function, and genetics of cellulases.
Biotechnology (Reading, Mass.) 1992;21():417-45.
1991: J Hallborn; M Walfridsson; U Airaksinen; H Ojamo; Bärbel Hahn-Hägerdal; Merja Penttilä; S Keräsnen
Xylitol production by recombinant Saccharomyces cerevisiae.
Bio/technology (Nature Publishing Company) 1991;9(11):1090-5.
1991: K Blomqvist; Maija-Liisa Suihko; J Knowles; Merja Penttilä
Chromosomal Integration and Expression of Two Bacterial alpha-Acetolactate Decarboxylase Genes in Brewer's Yeast.
Applied and environmental microbiology 1991;57(10):2796-803.
1991: J Edqvist; Sirkka Keränen; Merja Penttilä; K B Stråby; J K Knowles
Production of functional IgM Fab fragments by Saccharomyces cerevisiae.
Journal of biotechnology 1991;20(3):291-300.
1991: S Vanhanen; A Saloheimo; Marja Ilmén; J K Knowles; Merja Penttilä
Promoter structure and expression of the 3-phosphoglycerate kinase-encoding gene (pgk1) of Trichoderma reesei.
Gene 1991;106(1):129-33.
1991: JE Pitts; D Quinn; J Uusitalo; Merja Penttilä
Protein engineering of chymosin and expression in Trichoderma reesei.
Biochemical Society transactions 1991;19(3):663-6.
1991: D Quinn; JE Pitts; D Mantafounis; S E Lawler; J Uusitalo; Merja Penttilä; P Strop
Modifying the substrate specificity of chymosin.
Biochemical Society transactions 1991;19(3):267S.
1991: P Orprayoon; JE Pitts; PG Nugent; D Mantafounis; S E Lawler; Tom L Blundell; J Uusitalo; Merja Penttilä
Protein engineering of the surface loops of chymosin.
Biochemical Society transactions 1991;19(3):265S.
1991: S E Lawler; JE Pitts; D Mantafounis; R Gill; J Uusitalo; Merja Penttilä
Secretion of a chymosin-insulin fusion in Trichoderma reesei.
Biochemical Society transactions 1991;19(3):248S.
1991: A Harkki; A Mäntylä; Merja Penttilä; S Muttilainen; R Bühler; Pirkko Suominen; J Knowles; H Nevalainen
Genetic engineering of Trichoderma to produce strains with novel cellulase profiles.
Enzyme and microbial technology 1991;13(3):227-33.
1991: B D Zurbriggen; Merja Penttilä; Liisa Viikari; M J Bailey
Pilot scale production of a Trichoderma reesei endo-beta-glucanase by brewer's yeast.
Journal of biotechnology 1991;17(2):133-46.
1991: J M Uusitalo; K M Nevalainen; A M Harkki; J K Knowles; Merja Penttilä
Enzyme production by recombinant Trichoderma reesei strains.
Journal of biotechnology 1991;17(1):35-49.
1990: Maija-Liisa Suihko; K Blomqvist; Merja Penttilä; R Gisler; J Knowles
Recombinant brewer's yeast strains suitable for accelerated brewing.
Journal of biotechnology 1990;14(3-4):285-300.
1990: B Zurbriggen; M J Bailey; Merja Penttilä; K Poutanen; M Linko
Pilot scale production of a heterologous Trichoderma reesei cellulase by Saccharomyces cerevisiae.
Journal of biotechnology 1990;13(4):267-78.
1989: S Vanhanen; Merja Penttilä; P Lehtovaara; J Knowles
Isolation and characterization of the 3-phosphoglycerate kinase gene (pgk) from the filamentous fungus Trichoderma reesei.
Current genetics 1989;15(3):181-6.
1988: Markku Saloheimo; P Lehtovaara; Merja Penttilä; Tuula T Teeri; Jerry Ståhlberg; Gunnar Johansson; Göran Pettersson; Marc Claeyssens; P Tomme; J K Knowles
EGIII, a new endoglucanase from Trichoderma reesei: the characterization of both gene and enzyme.
Gene 1988;63(1):11-22.
1988: Merja Penttilä; L André; P Lehtovaara; M Bailey; Tuula T Teeri; J K Knowles
Efficient secretion of two fungal cellobiohydrolases by Saccharomyces cerevisiae.
Gene 1988;63(1):103-12.
1987: Merja Penttilä; L André; Markku Saloheimo; P Lehtovaara; J K Knowles
Expression of two Trichoderma reesei endoglucanases in the yeast Saccharomyces cerevisiae.
Yeast (Chichester, England) 1987;3(3):175-85.
1987: J Knowles; P Lehtovaara; Merja Penttilä; Tuula T Teeri; A Harkki; I Salovuori
The cellulase genes of Trichoderma.
Antonie van Leeuwenhoek 1987;53(5):335-41.
1987: Merja Penttilä; H Nevalainen; M Rättö; E Salminen; J Knowles
A versatile transformation system for the cellulolytic filamentous fungus Trichoderma reesei.
Gene 1987;61(2):155-64.
1986: Merja Penttilä; P Lehtovaara; H Nevalainen; Rama Bhikhabhai; J Knowles
Homology between cellulase genes of Trichoderma reesei: complete nucleotide sequence of the endoglucanase I gene.
Gene 1986;45(3):253-63.