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Giancarlo Pepeu

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Living Beings

Chemicals & Drugs

Anatomy

Procedures

Physiology

Avoidance Learning

Disorders

Alzheimer Disease

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Co-Publications
Name
53
Casamenti, Fiorella
32
Pedata, Felicita
32
Scali, Carla
31
Giovannini, Maria Grazia
18
Giovannelli, Lisa
13
Prosperi, Costanza
12
Pazzagli, M
10
Bianchi, Loria
10
Vannucchi, Maria Giuliana
9
Corsi, Claudia
9
Latini, Serena
6
Bellucci, Arianna
5
Della Corte, Laura
5
Corradetti, Renato
5
Bartolini, Luciano

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Publications

TOP 3
Pepeu Giancarlo; Giovannini Maria Grazia
Cholinesterase inhibitors and beyond.
Ballini Chiara; Corte Laura Della; Pazzagli Marta; Colivicchi Maria Alessandra; Pepeu Giancarlo; Tipton Keith F; Giovannini Maria Grazia
Extracellular levels of brain aspartate, glutamate and GABA during an inhibitory avoidance response in the rat.
Cerbai Francesca; Giovannini Maria Grazia; Melani Claudia; Enz Albert; Pepeu Giancarlo
N1phenethyl-norcymserine, a selective butyrylcholinesterase inhibitor, increases acetylcholine release in rat cerebral cortex: a comparison with donepezil and rivastigmine.

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All Publications

2009: Pepeu Giancarlo; Giovannini Maria Grazia
Cholinesterase inhibitors and beyond.
Current Alzheimer research 2009;6(2):86-96.
2008: Ballini Chiara; Corte Laura Della; Pazzagli Marta; Colivicchi Maria Alessandra; Pepeu Giancarlo; Tipton Keith F; Giovannini Maria Grazia
Extracellular levels of brain aspartate, glutamate and GABA during an inhibitory avoidance response in the rat.
Journal of neurochemistry 2008;106(3):1035-43.
2007: Cerbai Francesca; Giovannini Maria Grazia; Melani Claudia; Enz Albert; Pepeu Giancarlo
N1phenethyl-norcymserine, a selective butyrylcholinesterase inhibitor, increases acetylcholine release in rat cerebral cortex: a comparison with donepezil and rivastigmine.
European journal of pharmacology 2007;572(2-3):142-50.
2007: Gulino Rosario; Cataudella Tiziana; Casamenti Fiorella; Pepeu Giancarlo; Stanzani Stefania; Leanza Giampiero
Acetylcholine release from fetal tissue homotopically grafted to the motoneuron-depleted lumbar spinal cord. An in vivo microdialysis study in the awake rat.
Experimental neurology 2007;204(1):326-38.
2006: Bellucci Arianna; Luccarini Ilaria; Scali Carla; Prosperi Costanza; Giovannini Maria Grazia; Pepeu Giancarlo; Casamenti Fiorella
Cholinergic dysfunction, neuronal damage and axonal loss in TgCRND8 mice.
Neurobiology of disease 2006;23(2):260-72.
2006: Bini Giada; Pugliese Anna Maria; Pepeu Giancarlo; Chelazzi Guido
Neuronal control of the cardiac responses to osmotic stress in the gastropod limpet Patella caerulea.
Journal of experimental zoology. Part A, Comparative experimental biology 2006;305(6):472-9.
2006: Bini Giada; Pugliese Anna Maria; Pepeu Giancarlo; Chelazzi Guido
Tetrodotoxin prevents copper-induced bradycardia in gastropod limpets.
Environmental pollution (Barking, Essex : 1987) 2006;139(1):79-85.
2005: Greig Nigel H; Utsuki Tadanobu; Ingram Donald K; Wang Yue; Pepeu Giancarlo; Scali Carla; Yu Qian-Sheng; Mamczarz Jacek; Holloway Harold W; Giordano Tony; Chen DeMao; Furukawa Katsutoshi; Sambamurti Kumar; Brossi Arnold; Lahiri Debomoy K
Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(47):17213-8.
2005: Giovannini M G; Pazzagli M; Malmberg-Aiello P; Della Corte L; Rakovska A D; Cerbai F; Casamenti F; Pepeu G
Inhibition of acetylcholine-induced activation of extracellular regulated protein kinase prevents the encoding of an inhibitory avoidance response in the rat.
Neuroscience 2005;136(1):15-32.
2005: Boyd-Kimball D; Sultana R; Poon H Fai; Lynn B C; Casamenti F; Pepeu G; Klein J B; Butterfield D A
Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid beta-peptide (1-42) into rat brain: implications for Alzheimer's disease.
Neuroscience 2005;132(2):313-24.
2004: Luparini Maria Rita; Garrone Beatrice; Pazzagli Marta; Pinza Mario; Pepeu Giancarlo
A cortical GABA-5HT interaction in the mechanism of action of the antidepressant trazodone.
Progress in neuro-psychopharmacology & biological psychiatry 2004;28(7):1117-27.
2004: Prosperi C; Scali C; Barba M; Bellucci A; Giovannini M G; Pepeu G; Casamenti F
Comparison between flurbiprofen and its nitric oxide-releasing derivatives HCT-1026 and NCX-2216 on Abeta(1-42)-induced brain inflammation and neuronal damage in the rat.
International journal of immunopathology and pharmacology 2004;17(3):317-30.
2004: Rosi Susanna; Giovannini Maria Grazia; Lestage Pierre J; Muñoz Carmen; Corte Laura Della; Pepeu Giancarlo
S 18986, a positive modulator of AMPA receptors with cognition-enhancing properties, increases ACh release in the hippocampus of young and aged rat.
Neuroscience letters 2004;361(1-3):120-3.
2004: Pepeu Giancarlo; Giovannini Maria Grazia
Changes in acetylcholine extracellular levels during cognitive processes.
Learning & memory (Cold Spring Harbor, N.Y.) 2004;11(1):21-7.
2003: Giovannini M G; Scali C; Prosperi C; Bellucci A; Pepeu G; Casamenti F
Experimental brain inflammation and neurodegeneration as model of Alzheimer's disease: protective effects of selective COX-2 inhibitors.
International journal of immunopathology and pharmacology 2003;16(2 Suppl):31-40.
2003: Bianchi L; Ballini C; Colivicchi M A; Della Corte L; Giovannini M G; Pepeu G
Investigation on acetylcholine, aspartate, glutamate and GABA extracellular levels from ventral hippocampus during repeated exploratory activity in the rat.
Neurochemical research 2003;28(3-4):565-73.
2003: Scali C; Giovannini M G; Prosperi C; Bellucci A; Pepeu G; Casamenti F
The selective cyclooxygenase-2 inhibitor rofecoxib suppresses brain inflammation and protects cholinergic neurons from excitotoxic degeneration in vivo.
Neuroscience 2003;117(4):909-19.
2002: Giovannini Maria Grazia; Scali Carla; Prosperi Costanza; Bellucci Arianna; Vannucchi Maria Giuliana; Rosi Susanna; Pepeu Giancarlo; Casamenti Fiorella
Beta-amyloid-induced inflammation and cholinergic hypofunction in the rat brain in vivo: involvement of the p38MAPK pathway.
Neurobiology of disease 2002;11(2):257-74.
2002: Gamel-Didelon Katia; Corsi Claudia; Pepeu Giancarlo; Jung Heike; Gratzl Manfred; Mayerhofer Artur
An autocrine role for pituitary GABA: activation of GABA-B receptors and regulation of growth hormone levels.
Neuroendocrinology 2002;76(3):170-7.
2002: Scali C; Casamenti F; Bellucci A; Costagli C; Schmidt B; Pepeu G
Effect of subchronic administration of metrifonate, rivastigmine and donepezil on brain acetylcholine in aged F344 rats.
Journal of neural transmission (Vienna, Austria : 1996) 2002;109(7-8):1067-80.
2002: Scali Carla; Prosperi Costanza; Bracco Laura; Piccini Carolina; Baronti Roberto; Ginestroni Andrea; Sorbi Sandro; Pepeu Giancarlo; Casamenti Fiorella
Neutrophils CD11b and fibroblasts PGE(2) are elevated in Alzheimer's disease.
Neurobiology of aging 2002;23(4):523-30.
2002: Rossetti Zvani L; Carboni Sonia; Stancampiano Roberto; Sori Pierpaolo; Pepeu Giancarlo; Fadda Fabio
Bidirectional modulation of spatial working memory by ethanol.
Alcoholism, clinical and experimental research 2002;26(2):181-5.
2002: Ballmaier M; Casamenti F; Scali C; Mazzoncini R; Zoli M; Pepeu G; Spano P F
Rivastigmine antagonizes deficits in prepulse inhibition induced by selective immunolesioning of cholinergic neurons in nucleus basalis magnocellularis.
Neuroscience 2002;114(1):91-8.
2001: Prosperi C; Scali C; Pepeu G; Casamenti F
NO-flurbiprofen attenuates excitotoxin-induced brain inflammation, and releases nitric oxide in the brain.
Japanese journal of pharmacology 2001;86(2):230-5.
2001: Ishimaru H; Casamenti F; Uéda K; Maruyama Y; Pepeu G
Changes in presynaptic proteins, SNAP-25 and synaptophysin, in the hippocampal CA1 area in ischemic gerbils.
Brain research 2001;903(1-2):94-101.
2001: Kopf S R; Benton R S; Kalfin R; Giovannini M G; Pepeu G
NO synthesis inhibition decreases cortical ACh release and impairs retention of a conditioned response.
Brain research 2001;894(1):141-4.
2001: Pepeu G
Overview and perspective on the therapy of Alzheimer's disease from a preclinical viewpoint.
Progress in neuro-psychopharmacology & biological psychiatry 2001;25(1):193-209.
2001: Ballmaier M; Casamenti F; Zoli M; Pepeu G; Spano P
Selective immunolesioning of cholinergic neurons in nucleus basalis magnocellularis impairs prepulse inhibition of acoustic startle.
Neuroscience 2001;108(2):299-305.
2001: Giovannini M G; Rakovska A; Benton R S; Pazzagli M; Bianchi L; Pepeu G
Effects of novelty and habituation on acetylcholine, GABA, and glutamate release from the frontal cortex and hippocampus of freely moving rats.
Neuroscience 2001;106(1):43-53.
2000: Scali C; Prosperi C; Vannucchi M G; Pepeu G; Casamenti F
Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: implication in Alzheimer's disease.
The European journal of neuroscience 2000;12(6):1900-12.
2000: Giovannelli L; Veltri M; Casamenti F; Pepeu G
NGF treatment potentiates c-fos expression in the rat nucleus basalis upon excitotoxic lesion with quisqualic acid.
Brain research 2000;853(1):136-41.
1999: Corsi C; Melani A; Bianchi L; Pepeu G; Pedata F
Effect of adenosine A2A receptor stimulation on GABA release from the striatum of young and aged rats in vivo.
Neuroreport 1999;10(18):3933-7.
1999: Pazzagli M; Giovannini M G; Pepeu G
Trazodone increases extracellular serotonin levels in the frontal cortex of rats.
European journal of pharmacology 1999;383(3):249-57.
1999: Latini S; Bordoni F; Corradetti R; Pepeu G; Pedata F
Effect of A2A adenosine receptor stimulation and antagonism on synaptic depression induced by in vitro ischaemia in rat hippocampal slices.
British journal of pharmacology 1999;128(5):1035-44.
1999: Melani A; Pantoni L; Corsi C; Bianchi L; Monopoli A; Bertorelli R; Pepeu G; Pedata F
Striatal outflow of adenosine, excitatory amino acids, gamma-aminobutyric acid, and taurine in awake freely moving rats after middle cerebral artery occlusion: correlations with neurological deficit and histopathological damage.
Stroke; a journal of cerebral circulation 1999;30(11):2448-54; discussion 2455.
1999: Kopf S R; Melani A; Pedata F; Pepeu G
Adenosine and memory storage: effect of A(1) and A(2) receptor antagonists.
Psychopharmacology 1999;146(2):214-9.
1999: Zhelyazkova-Savova M; Giovannini M G; Pepeu G
Systemic chlorophenylpiperazine increases acetylcholine release from rat hippocampus-implication of 5-HT2C receptors.
Pharmacological research : the official journal of the Italian Pharmacological Society 1999;40(2):165-70.
1999: Scali C; Prosperi C; Giovannelli L; Bianchi L; Pepeu G; Casamenti F
Beta(1-40) amyloid peptide injection into the nucleus basalis of rats induces microglia reaction and enhances cortical gamma-aminobutyric acid release in vivo.
Brain research 1999;831(1-2):319-21.
1999: Corsi C; Melani A; Bianchi L; Pepeu G; Pedata F
Striatal A2A adenosine receptors differentially regulate spontaneous and K+-evoked glutamate release in vivo in young and aged rats.
Neuroreport 1999;10(4):687-91.
1999: Ceccarelli I; Casamenti F; Massafra C; Pepeu G; Scali C; Aloisi A M
Effects of novelty and pain on behavior and hippocampal extracellular ACh levels in male and female rats.
Brain research 1999;815(2):169-76.
1999: Casamenti F; Prosperi C; Scali C; Giovannelli L; Colivicchi M A; Faussone-Pellegrini M S; Pepeu G
Interleukin-1beta activates forebrain glial cells and increases nitric oxide production and cortical glutamate and GABA release in vivo: implications for Alzheimer's disease.
Neuroscience 1999;91(3):831-42.
1998: Casamenti F; Prosperi C; Scali C; Giovannelli L; Pepeu G
Morphological, biochemical and behavioural changes induced by neurotoxic and inflammatory insults to the nucleus basalis.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1998;16(7-8):705-14.
1998: Giovannelli L; Scali C; Faussone-Pellegrini M S; Pepeu G; Casamenti F
Long-term changes in the aggregation state and toxic effects of beta-amyloid injected into the rat brain.
Neuroscience 1998;87(2):349-57.
1998: Rakovska A; Giovannini M G; Della Corte L; Kalfin R; Bianchi L; Pepeu G
Neurotensin modulation of acetylcholine and GABA release from the rat hippocampus: an in vivo microdialysis study.
Neurochemistry international 1998;33(4):335-40.
1998: Giovannini M G; Scali C; Bartolini L; Schmidt B; Pepeu G
Effect of subchronic treatment with metrifonate and tacrine on brain cholinergic function in aged F344 rats.
European journal of pharmacology 1998;354(1):17-24.
1998: Latini S; Bordoni F; Corradetti R; Pepeu G; Pedata F
Temporal correlation between adenosine outflow and synaptic potential inhibition in rat hippocampal slices during ischemia-like conditions.
Brain research 1998;794(2):325-8.
1998: Giovannini M G; Rakovska A; Della Corte L; Bianchi L; Pepeu G
Activation of non-NMDA receptors stimulates acetylcholine and GABA release from dorsal hippocampus: a microdialysis study in the rat.
Neuroscience letters 1998;243(1-3):152-6.
1998: Giovannini M G; Bartolini L; Kopf S R; Pepeu G
Acetylcholine release from the frontal cortex during exploratory activity.
Brain research 1998;784(1-2):218-27.
1998: Giovannelli L; Casamenti F; Pepeu G
C-fos expression in the rat nucleus basalis upon excitotoxic lesion with quisqualic acid: a study in adult and aged animals.
Journal of neural transmission (Vienna, Austria : 1996) 1998;105(8-9):935-48.
1997: Scali C; Giovannini M G; Prosperi C; Bartolini L; Pepeu G
Tacrine administration enhances extracellular acetylcholine in vivo and restores the cognitive impairment in aged rats.
Pharmacological research : the official journal of the Italian Pharmacological Society 1997;36(6):463-9.
1997: Zhelyazkova-Savova M; Giovannini M G; Pepeu G
Increase of cortical acetylcholine release after systemic administration of chlorophenylpiperazine in the rat: an in vivo microdialysis study.
Neuroscience letters 1997;236(3):151-4.
1997: Giovannini M G; Giovannelli L; Bianchi L; Kalfin R; Pepeu G
Glutamatergic modulation of cortical acetylcholine release in the rat: a combined in vivo microdialysis, retrograde tracing and immunohistochemical study.
The European journal of neuroscience 1997;9(8):1678-89.
1997: Vannucchi M G; Scali C; Kopf S R; Pepeu G; Casamenti F
Selective muscarinic antagonists differentially affect in vivo acetylcholine release and memory performances of young and aged rats.
Neuroscience 1997;79(3):837-46.
1997: Scali C; Giovannini M G; Bartolini L; Prosperi C; Hinz V; Schmidt B; Pepeu G
Effect of metrifonate on extracellular brain acetylcholine and object recognition in aged rats.
European journal of pharmacology 1997;325(2-3):173-80.
1997: Corsi C; Pazzagli M; Bianchi L; Della Corte L; Pepeu G; Pedata F
In vivo amino acid release from the striatum of aging rats: adenosine modulation.
Neurobiology of aging 1997;18(2):243-50.
1997: Ghelardini C; Gualtieri F; Novella Romanelli M; Angeli P; Pepeu G; Grazia Giovannini M; Casamenti F; Malmberg-Aiello P; Giotti A; Bartolini A
Stereoselective increase in cholinergic transmission by R-(+)-hyoscyamine.
Neuropharmacology 1997;36(3):281-94.
1997: Aloisi A M; Casamenti F; Scali C; Pepeu G; Carli G
Effects of novelty, pain and stress on hippocampal extracellular acetylcholine levels in male rats.
Brain research 1997;748(1-2):219-26.
1997: Giovannini M G; Casamenti F; Bartolini L; Pepeu G
The brain cholinergic system as a target of cognition enhancers.
Behavioural brain research 1997;83(1-2):1-5.
1997: Latini S; Pedata F; Pepeu G
The contribution of different types of calcium channels to electrically-evoked adenosine release from rat hippocampal slices.
Naunyn-Schmiedeberg's archives of pharmacology 1997;355(2):250-5.
1996: Blandina P; Giorgetti M; Bartolini L; Cecchi M; Timmerman H; Leurs R; Pepeu G; Giovannini M G
Inhibition of cortical acetylcholine release and cognitive performance by histamine H3 receptor activation in rats.
British journal of pharmacology 1996;119(8):1656-64.
1996: Latini S; Pazzagli M; Pepeu G; Pedata F
A2 adenosine receptors: their presence and neuromodulatory role in the central nervous system.
General pharmacology 1996;27(6):925-33.
1996: Orsetti M; Casamenti F; Pepeu G
Enhanced acetylcholine release in the hippocampus and cortex during acquisition of an operant behavior.
Brain research 1996;724(1):89-96.
1996: Pepeu G; Pepeu I M; Amaducci L
A review of phosphatidylserine pharmacological and clinical effects. Is phosphatidylserine a drug for the ageing brain?
Pharmacological research : the official journal of the Italian Pharmacological Society 1996;33(2):73-80.
1996: Bartolini L; Casamenti F; Pepeu G
Aniracetam restores object recognition impaired by age, scopolamine, and nucleus basalis lesions.
Pharmacology, biochemistry, and behavior 1996;53(2):277-83.
1996: Latini S; Corsi C; Pedata F; Pepeu G
The source of brain adenosine outflow during ischemia and electrical stimulation.
Neurochemistry international 1996;28(1):113-8.
1996: Pepeu G; Giovannelli L; Casamenti F; Scali C; Bartolini L
Amyloid beta-peptides injection into the cholinergic nuclei: morphological, neurochemical and behavioral effects.
Progress in brain research 1996;109():273-82.
1996: Ghelardini C; Galeotti N; Casamenti F; Malmberg-Aiello P; Pepeu G; Gualtieri F; Bartolini A
Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8.
Life sciences 1996;58(25):2297-309.
1995: Scali C; Vannucchi M G; Pepeu G; Casamenti F
Peripherally injected scopolamine differentially modulates acetylcholine release in vivo in the young and aged rats.
Neuroscience letters 1995;197(3):171-4.
1995: Latini S; Corsi C; Pedata F; Pepeu G
The source of brain adenosine outflow during ischemia and electrical stimulation.
Neurochemistry international 1995;27(3):239-44.
1995: Giovannelli L; Casamenti F; Scali C; Bartolini L; Pepeu G
Differential effects of amyloid peptides beta-(1-40) and beta-(25-35) injections into the rat nucleus basalis.
Neuroscience 1995;66(4):781-92.
1995: Pazzagli M; Corsi C; Fratti S; Pedata F; Pepeu G
Regulation of extracellular adenosine levels in the striatum of aging rats.
Brain research 1995;684(1):103-6.
1995: Vannucchi M G; Pepeu G
Muscarinic receptor modulation of acetylcholine release from rat cerebral cortex and hippocampus.
Neuroscience letters 1995;190(1):53-6.
1995: Giovannini M G; Camilli F; Mundula A; Bianchi L; Colivicchi M A; Pepeu G
Differential regulation by N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors of acetylcholine release from the rat striatum in vivo.
Neuroscience 1995;65(2):409-15.
1994: Giovannini M G; Mutolo D; Bianchi L; Michelassi A; Pepeu G
NMDA receptor antagonists decrease GABA outflow from the septum and increase acetylcholine outflow from the hippocampus: a microdialysis study.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(3 Pt 1):1358-65.
1994: Scali C; Casamenti F; Pazzagli M; Bartolini L; Pepeu G
Nerve growth factor increases extracellular acetylcholine levels in the parietal cortex and hippocampus of aged rats and restores object recognition.
Neuroscience letters 1994;170(1):117-20.
1994: Pazzagli M; Corsi C; Latini S; Pedata F; Pepeu G
In vivo regulation of extracellular adenosine levels in the cerebral cortex by NMDA and muscarinic receptors.
European journal of pharmacology 1994;254(3):277-82.
1994: Abe E; Casamenti F; Giovannelli L; Scali C; Pepeu G
Administration of amyloid beta-peptides into the medial septum of rats decreases acetylcholine release from hippocampus in vivo.
Brain research 1994;636(1):162-4.
1994: Pepeu G; Oderfeld-Nowak B; Casamenti F
CNS pharmacology of gangliosides.
Progress in brain research 1994;101():327-35.
1994: Pepeu G
Memory disorders: novel treatments, clinical perspective.
Life sciences 1994;55(25-26):2189-94.
1994: Pepeu G; Giovannelli L
The central cholinergic system during aging.
Progress in brain research 1994;100():67-71.
1994: Pepeu G; Marconcini Pepeu I
Dysfunction of the brain cholinergic system during aging and after lesions of the nucleus basalis of Meynert.
Journal of neural transmission. Supplementum 1994;44():189-94.
1994: Casamenti F; Scali C; Giovannelli L; Faussone-Pellegrini M S; Pepeu G
Effect of nerve growth factor and GM1 ganglioside on the recovery of cholinergic neurons after a lesion of the nucleus basalis in aging rats.
Journal of neural transmission. Parkinson's disease and dementia section 1994;7(3):177-93.
1993: Latini S; Pedata F; Pepeu G
Effect of idebenone on adenosine outflow and adenine nucleotide level in hippocampal slices under ischemia-like conditions.
European journal of pharmacology 1993;249(1):65-70.
1993: Casamenti F; Scali C; Vannucchi M G; Bartolini L; Pepeu G
Long-term ethanol consumption by rats: effect on acetylcholine release in vivo, choline acetyltransferase activity, and behavior.
Neuroscience 1993;56(2):465-71.
1993: Pedata F; Latini S; Pugliese A M; Pepeu G
Investigations into the adenosine outflow from hippocampal slices evoked by ischemia-like conditions.
Journal of neurochemistry 1993;61(1):284-9.
1993: Zupan G; Casamenti F; Scali C; Pepeu G
Lesions of the nucleus basalis magnocellularis in immature rats: short- and long-term biochemical and behavioral changes.
Pharmacology, biochemistry, and behavior 1993;45(1):19-25.
1993: Pazzagli M; Pedata F; Pepeu G
Effect of K+ depolarization, tetrodotoxin, and NMDA receptor inhibition on extracellular adenosine levels in rat striatum.
European journal of pharmacology 1993;234(1):61-5.
1993: Pepeu G; Casamenti F; Pepeu I M; Scali C
The brain cholinergic system in ageing mammals.
Journal of reproduction and fertility. Supplement 1993;46():155-62.
1993: Pepeu G
Overview and future directions of CNS cholinergic mechanisms.
Progress in brain research 1993;98():455-8.
1992: Bartolini L; Risaliti R; Pepeu G
Effect of scopolamine and nootropic drugs on rewarded alternation in a T-maze.
Pharmacology, biochemistry, and behavior 1992;43(4):1161-4.
1992: Corradetti R; Ballerini L; Pugliese A M; Pepeu G
Serotonin blocks the long-term potentiation induced by primed burst stimulation in the CA1 region of rat hippocampal slices.
Neuroscience 1992;46(3):511-8.
1992: Pepeu G; Casamenti F; Scali C; Jeglinski W
Aging of brain cholinergic neurons: pharmacological interventions.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():31A-32A.
1991: Giovannini M G; Spignoli G; Carlà V; Pepeu G
A decrease in brain catecholamines prevents oxiracetam antagonism of the effects of scopolamine on memory and brain acetylcholine.
Pharmacological research : the official journal of the Italian Pharmacological Society 1991;24(4):395-405.
1991: Pedata F; Pazzagli M; Pepeu G
Endogenous adenosine release from hippocampal slices: excitatory amino acid agonists stimulate release, antagonists reduce the electrically-evoked release.
Naunyn-Schmiedeberg's archives of pharmacology 1991;344(5):538-43.
1991: Giovannini M G; Lacey G; Pepeu G; Nistri A
Release of endogenous glutamate and aspartate from the frog spinal cord in vitro.
European journal of pharmacology 1991;195(1):47-53.
1991: Casamenti F; Scali C; Pepeu G
Phosphatidylserine reverses the age-dependent decrease in cortical acetylcholine release: a microdialysis study.
European journal of pharmacology 1991;194(1):11-6.
1991: Giovannini M G; Casamenti F; Nistri A; Paoli F; Pepeu G
Effect of thyrotropin releasing hormone (TRH) on acetylcholine release from different brain areas investigated by microdialysis.
British journal of pharmacology 1991;102(2):363-8.
1990: Pepeu G; Pepeu I M; Casamenti F
The validity of animal models in the search for drugs for the aging brain.
Drug design and delivery 1990;7(1):1-10.
1990: Pedata F; Pazzagli M; Tilli S; Pepeu G
Regional differences in the electrically stimulated release of endogenous and radioactive adenosine and purine derivatives from rat brain slices.
Naunyn-Schmiedeberg's archives of pharmacology 1990;342(4):447-53.
1990: Vannucchi M G; Casamenti F; Pepeu G
Decrease of acetylcholine release from cortical slices in aged rats: investigations into its reversal by phosphatidylserine.
Journal of neurochemistry 1990;55(3):819-25.
1990: Pazzagli M; Pedata F; Pepeu G
Release of endogenous adenosine and its metabolites from electrically stimulated cortical, hippocampal and striatal slices of the rat.
Pharmacological research : the official journal of the Italian Pharmacological Society 1990;22 Suppl 1():1-2.
1990: Pugliese A M; Corradetti R; Ballerini L; Pepeu G
Effect of the nootropic drug oxiracetam on field potentials of rat hippocampal slices.
British journal of pharmacology 1990;99(1):189-93.
1990: Pepeu G; Giovannelli L
Effect of aging on calcium cytosolic concentration in rat cortical synaptosomes.
Annali dell'Istituto superiore di sanità 1990;26(1):49-53.
1990: Pepeu G; Spignoli G
Neurochemical actions of "nootropic drugs".
Advances in neurology 1990;51():247-52.
1990: Pepeu G; Casamenti F; Giovannini M G; Vannucchi M G; Pedata F
Principal aspects of the regulation of acetylcholine release in the brain.
Progress in brain research 1990;84():273-8.
1990: Paoli F; Spignoli G; Pepeu G
Oxiracetam and D-pyroglutamic acid antagonize a disruption of passive avoidance behaviour induced by the N-methyl-D-aspartate receptor antagonist 2-amino-5-phosphonovalerate.
Psychopharmacology 1990;100(1):130-1.
1990: Casamenti F; Milan F; Pepeu G
Lesions of the nucleus basalis magnocellularis in the rat: morphological, biochemical and behavioral reparative effect of nerve growth factor and ganglioside GM1.
Acta neurobiologiae experimentalis 1990;50(4-5):461-73.
1989: Pepeu G; Spignoli G; Giovannini M G; Magnani M
The relationship between the behavioral effects of cognition-enhancing drugs and brain acetylcholine. Nootropic drugs and brain acetylcholine.
Pharmacopsychiatry 1989;22 Suppl 2():116-9.
1989: Casamenti F; Di Patre P L; Milan F; Petrelli L; Pepeu G
Effects of nerve growth factor and GM1 ganglioside on the number and size of cholinergic neurons in rats with unilateral lesion of the nucleus basalis.
Neuroscience letters 1989;103(1):87-91.
1989: Giovannelli L; Pepeu G
Effect of age on K+-induced cytosolic Ca2+ changes in rat cortical synaptosomes.
Journal of neurochemistry 1989;53(2):392-8.
1989: Di Patre P L; Abbamondi A; Bartolini L; Pepeu G
GM1 ganglioside counteracts cholinergic and behavioral deficits induced in the rat by intracerebral injection of vincristine.
European journal of pharmacology 1989;162(1):43-50.
1989: Di Patre P L; Casamenti F; Cenni A; Pepeu G
Interaction between nerve growth factor and GM1 monosialoganglioside in preventing cortical choline acetyltransferase and high affinity choline uptake decrease after lesion of the nucleus basalis.
Brain research 1989;480(1-2):219-24.
1989: Pepeu G; Spignoli G
Nootropic drugs and brain cholinergic mechanisms.
Progress in neuro-psychopharmacology & biological psychiatry 1989;13 Suppl():S77-88.
1989: Pedata F; Di Patre P L; Giovannini M G; Pazzagli M; Pepeu G
Cholinergic and noradrenergic denervations decrease labelled purine release from electrically stimulated rat cortical slices.
Neuroscience 1989;32(3):629-36.
1988: Pedata F; Magnani M; Pepeu G
Muscarinic modulation of purine release from electrically stimulated rat cortical slices.
Journal of neurochemistry 1988;50(4):1074-9.
1988: Pepeu G
Acetylcholine and brain aging.
Pharmacological research communications 1988;20(2):91-7.
1988: Casamenti F; Di Patre P L; Bartolini L; Pepeu G
Unilateral and bilateral nucleus basalis lesions: differences in neurochemical and behavioural recovery.
Neuroscience 1988;24(1):209-15.
1988: Giovannelli L; Giovannini M G; Pedata F; Pepeu G
Purinergic modulation of cortical acetylcholine release is decreased in aging rats.
Experimental gerontology 1988;23(3):175-81.
1987: Spignoli G; Magnani M; Giovannini M G; Pepeu G
Effect of pyroglutamic acid stereoisomers on ECS and scopolamine-induced memory disruption and brain acetylcholine levels in the rat.
Pharmacological research communications 1987;19(12):901-12.
1987: Vannucchi M G; Pepeu G
Effect of phosphatidylserine on acetylcholine release and content in cortical slices from aging rats.
Neurobiology of aging 1987;8(5):403-7.
1987: Magnani M; Florian A; Casamenti F; Pepeu G
An analysis of cholecystokinin-induced increase in acetylcholine output from cerebral cortex of the rat.
Neuropharmacology 1987;26(8):1207-10.
1987: Spignoli G; Pepeu G
Interactions between oxiracetam, aniracetam and scopolamine on behavior and brain acetylcholine.
Pharmacology, biochemistry, and behavior 1987;27(3):491-5.
1986: Corradetti R; Pedata F; Pepeu G; Vannucchi M G
Chronic caffeine treatment reduces caffeine but not adenosine effects on cortical acetylcholine release.
British journal of pharmacology 1986;88(3):671-6.
1986: Pedata F; Giovannelli L; De Sarno P; Pepeu G
Effect of adenosine, adenosine derivatives, and caffeine on acetylcholine release from brain synaptosomes: interaction with muscarinic autoregulatory mechanisms.
Journal of neurochemistry 1986;46(5):1593-8.
1986: Spignoli G; Pedata F; Giovannelli L; Banfi S; Moroni F; Pepeu G
Effect of oxiracetam and piracetam on central cholinergic mechanisms and active-avoidance acquisition.
Clinical neuropharmacology 1986;9 Suppl 3():S39-47.
1986: Pepeu G; Casamenti F; Pedata F; Cosi C; Pepeu I M
Are the neurochemical and behavioral changes induced by lesions of the nucleus basalis in the rat a model of Alzheimer's disease?
Progress in neuro-psychopharmacology & biological psychiatry 1986;10(3-5):541-51.
1985: Casamenti F; Bracco L; Bartolini L; Pepeu G
Effects of ganglioside treatment in rats with a lesion of the cholinergic forebrain nuclei.
Brain research 1985;338(1):45-52.
1985: Pedata F; Giovannelli L; Spignoli G; Giovannini M G; Pepeu G
Phosphatidylserine increases acetylcholine release from cortical slices in aged rats.
Neurobiology of aging 1985;6(4):337-9.
1984: Pedata F; Pepeu G; Spignoli G
Biphasic effect of methylxanthines on acetylcholine release from electrically-stimulated brain slices.
British journal of pharmacology 1984;83(1):69-73.
1984: Spignoli G; Pedata F; Pepeu G
A1 and A2 adenosine receptors modulate acetylcholine release from brain slices.
European journal of pharmacology 1984;97(3-4):341-2.
1984: Pedata F; Spignoli G; Pepeu G C
Effect of adenosine and caffeine on acetylcholine release from electrically stimulated brain slices.
Annali dell'Istituto superiore di sanità 1984;20(1):33-7.
1984: Pedata F; Giovannelli L; Pepeu G
GM1 ganglioside facilitates the recovery of high-affinity choline uptake in the cerebral cortex of rats with a lesion of the nucleus basalis magnocellularis.
Journal of neuroscience research 1984;12(2-3):421-7.
1982: Lo Conte G; Bartolini L; Casamenti F; Marconcini-Pepeu I; Pepeu G
Lesions of cholinergic forebrain nuclei: changes in avoidance behavior and scopolamine actions.
Pharmacology, biochemistry, and behavior 1982;17(5):933-7.
1982: Pedata F; Lo Conte G; Sorbi S; Marconcini-Pepeu I; Pepeu G
Changes in high affinity choline uptake in rat cortex following lesions of the magnocellular forebrain nuclei.
Brain research 1982;233(2):359-67.

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