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Maritta Perälä

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Saija Marika Haapa-Paananen; Sampsa Hautaniemi; Kirsi Hellström; Olli Kallioniemi; Pekka Kohonen; Ping Chen; Maritta Perälä
Functional Profiling of Precursor MicroRNAs Identifies MicroRNAs Essential for Glioma Proliferation.
Paula Vainio; Gerald W Verhaegh; Maija Wolf; Henrik Edgren; Tao He; Kristiina Iljin; Pekka Kohonen; John-Patrick Mpindi; Maritta Perälä; Jack Schalken; Frank Smit; Olli Kallioniemi
Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer.
Sirkku Pollari; Jukka P Rissanen; Anni Wärri; Theresa A Guise; Jussi M Halleen; Rami S Käkönen; Olli Kallioniemi; Anne Marjamäki; Khalid S Mohammad; Liisa Nissinen; Maritta Perälä; Marjo Pihlavisto; Sanna-Maria Käkönen
Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis.

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All Publications

2013: Saija Marika Haapa-Paananen; Sampsa Hautaniemi; Kirsi Hellström; Olli Kallioniemi; Pekka Kohonen; Ping Chen; Maritta Perälä
Functional Profiling of Precursor MicroRNAs Identifies MicroRNAs Essential for Glioma Proliferation.
PloS one 2013;8(4):e60930.
2012: Paula Vainio; Gerald W Verhaegh; Maija Wolf; Henrik Edgren; Tao He; Kristiina Iljin; Pekka Kohonen; John-Patrick Mpindi; Maritta Perälä; Jack Schalken; Frank Smit; Olli Kallioniemi
Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer.
The Prostate 2012;72(7):789-802.
2012: Sirkku Pollari; Jukka P Rissanen; Anni Wärri; Theresa A Guise; Jussi M Halleen; Rami S Käkönen; Olli Kallioniemi; Anne Marjamäki; Khalid S Mohammad; Liisa Nissinen; Maritta Perälä; Marjo Pihlavisto; Sanna-Maria Käkönen
Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis.
Molecular cancer research : MCR 2012;10(5):597-604.
2012: Saija Marika Haapa-Paananen; Hannu Haapasalo; Heikki Joensuu; S Kiviluoto; Pekka Kohonen; J P Mpindi; Maritta Perälä; Marjut Puputti; Olli Tynninen; M Waltari; Olli Kallioniemi
HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation.
Oncogene 2012;31(10):1299-310.
2012: Paula Vainio; Kalle Alanen; Vidal Fey; Olli Kallioniemi; Pekka Kohonen; Tuomas Mirtti; John-Patrick Mpindi; Maritta Perälä; Kristiina Iljin
High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer.
PloS one 2012;7(6):e39801.
2012: Sirkku Pollari; Vidal Fey; Sanna-Maria Käkönen; Suvi-Katri Leivonen; Maritta Perälä; Olli Kallioniemi
Identification of microRNAs inhibiting TGF-β-induced IL-11 production in bone metastatic breast cancer cells.
PloS one 2012;7(5):e37361.
2011: Suvi-Katri Leivonen; Päivi Ostling; Garry L Corthals; Olli Kallioniemi; Pekka Kohonen; Anne Rokka; Maritta Perälä
Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact.
Molecular & cellular proteomics : MCP 2011;10(7):M110.005322.
2011: Paula Vainio; Santosh Gupta; Kirsi Ketola; Tuomas Mirtti; John-Patrick Mpindi; Pekka Kohonen; Vidal Fey; Maritta Perälä; Frank Smit; Gerald W Verhaegh; Jack Schalken; Kalle Alanen; Olli Kallioniemi; Kristiina Iljin
Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer.
The American journal of pathology 2011;178(2):525-36.
2005: Eveliina Jakkula; Miia Melkoniemi; I Kiviranta; Jaana Lohiniva; Susanna Räinä; Maritta Perälä; Matthew L Warman; K Ahonen; Heikki Kröger; Harald HH Goring; Leena Ala-Kokko
The role of sequence variations within the genes encoding collagen II, IX and XI in non-syndromic, early-onset osteoarthritis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2005;13(6):497-507.
2003: David Olsen; Chunlin Yang; Michael Bodo; Robert Chang; Scott Leigh; Julio Baez; David Carmichael; Maritta Perälä; Eija-Riitta Hämäläinen; Marko Jarvinen; James W Polarek
Recombinant collagen and gelatin for drug delivery.
Advanced drug delivery reviews 2003;55(12):1547-67.
2002: Heli Salminen; Anna-Marja Säämänen; M N Vankemmelbeke; P K Auho; Maritta Perälä; Eero Vuorio
Differential expression patterns of matrix metalloproteinases and their inhibitors during development of osteoarthritis in a transgenic mouse model.
Annals of the rheumatic diseases 2002;61(7):591-7.
2001: Malwina Czarny-Ratajczak; Jaana Lohiniva; Piotr Rogala; Kazimierz Kozlowski; Maritta Perälä; L Carter; T D Spector; Lukasz Kolodziej; Ulpu Seppänen; R Glazar; J Królewski; Anna Latos-Bielenska; Leena Ala-Kokko
A mutation in COL9A1 causes multiple epiphyseal dysplasia: further evidence for locus heterogeneity.
American journal of human genetics 2001;69(5):969-80.
2001: Petteri Paassilta; Jaana Lohiniva; Harald HH Goring; Maritta Perälä; Susanna Räinä; Jaro Karppinen; M Hakala; T Palm; Heikki Kröger; I Kaitila; Heikki Vanharanta; Jürg Ott; Leena Ala-Kokko
Identification of a novel common genetic risk factor for lumbar disk disease.
JAMA : the journal of the American Medical Association 2001;285(14):1843-9.
2000: Heli Salminen; Maritta Perälä; P Lorenzo; Dick Heinegård; D Heinegård; Anna-Marja Säämänen; Eero Vuorio
Up-regulation of cartilage oligomeric matrix protein at the onset of articular cartilage degeneration in a transgenic mouse model of osteoarthritis.
Arthritis and rheumatism 2000;43(8):1742-8.
1999: Tero Pihlajamaa; Maritta Perälä; Mirka Marjanna Vuoristo; Minna Nokelainen; Michael Bodo; T Schulthess; Eero Vuorio; Rupert Timpl; J Engel; Leena Ala-Kokko
Characterization of recombinant human type IX collagen. Association of alpha chains into homotrimeric and heterotrimeric molecules.
The Journal of biological chemistry 1999;274(32):22464-8.
1999: S Annunen; Petteri Paassilta; Jaana Lohiniva; Maritta Perälä; Tero Pihlajamaa; Jaro Karppinen; Osmo Tervonen; Heikki Kröger; Seppo Lähde; Heikki Vanharanta; Lasse Ryhänen; Harald HH Goring; Jürg Ott; Darwin J Prockop; Leena Ala-Kokko
An allele of COL9A2 associated with intervertebral disc disease.
Science (New York, N.Y.) 1999;285(5426):409-12.
1998: Marja-Liisa Savontaus; Tapio Ihanamäki; Maritta Perälä; MP Metsäranta; Minna Sandberg-Lall; Eero Vuorio
Expression of type II and IX collagen isoforms during normal and pathological cartilage and eye development.
Histochemistry and cell biology 1998;110(2):149-59.
1998: Tero Pihlajamaa; Mirka Marjanna Vuoristo; S Annunen; Maritta Perälä; Darwin J Prockop; Leena Ala-Kokko
Human COL9A1 and COL9A2 genes. Two genes of 90 and 15 kb code for similar polypeptides of the same collagen molecule.
Matrix biology : journal of the International Society for Matrix Biology 1998;17(3):237-41.
1997: Maritta Perälä; Marja-Liisa Savontaus; MP Metsäranta; Eero Vuorio
Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis.
The Biochemical journal 1997;324 ( Pt 1)():209-16.
1995: Petri Virolainen; Maritta Perälä; Eero Vuorio; Hannu T Aro
Expression of matrix genes during incorporation of cancellous bone allografts and autografts.
Clinical orthopaedics and related research 1995;(317):263-72.
1995: A Hiltunen; MP Metsäranta; Maritta Perälä; Anna-Marja Säämänen; Hannu T Aro; Eero Vuorio
Expression of type VI, IX and XI collagen genes and alternative splicing of type II collagen transcripts in fracture callus tissue in mice.
FEBS letters 1995;364(2):171-4.
1994: Maritta Perälä; K Elima; MP Metsäranta; R Rosati; Benoit de Crombrugghe; Eero Vuorio
The exon structure of the mouse alpha 2(IX) collagen gene shows unexpected divergence from the chick gene.
The Journal of biological chemistry 1994;269(7):5064-71.
1993: Maritta Perälä; M Hänninen; J Hästbacka; K Elima; Eero Vuorio
Molecular cloning of the human alpha 2(IX) collagen cDNA and assignment of the human COL9A2 gene to chromosome 1.
FEBS letters 1993;319(1-2):177-80.
1993: K Elima; I Eerola; R Rosati; MP Metsäranta; Silvio Garofalo; Maritta Perälä; Benoit de Crombrugghe; Eero Vuorio
The mouse collagen X gene: complete nucleotide sequence, exon structure and expression pattern.
The Biochemical journal 1993;289 ( Pt 1)():247-53.
1992: Maritta Perälä; H Hirvonen; H Kalimo; S Ala-Uotila; John W Regan; K E Akerman; Mika Scheinin
Differential expression of two alpha 2-adrenergic receptor subtype mRNAs in human tissues.
Brain research. Molecular brain research 1992;16(1-2):57-63.
1992: Anne Marjamäki; S Ala-Uotila; K Luomala; Maritta Perälä; CC Jansson; Markku Jalkanen; John W Regan; Mika Scheinin
Stable expression of recombinant human alpha 2-adrenoceptor subtypes in two mammalian cell lines: characterization with [3H]rauwolscine binding, inhibition of adenylate cyclase and RNase protection assay.
Biochimica et biophysica acta 1992;1134(2):169-77.
1992: K Elima; MP Metsäranta; Jaana Kallio; Maritta Perälä; I Eerola; Silvio Garofalo; Benoit de Crombrugghe; Eero Vuorio
Specific hybridization probes for mouse alpha 2(IX) and alpha 1(X) collagen mRNAs.
Biochimica et biophysica acta 1992;1130(1):78-80.
1991: Reijo Lahti; Maritta Perälä; Pirkko Heikinheimo; T Pitkäranta; E Kukko-Kalske; J Heinonen
Characterization of the 5' flanking region of the Escherichia coli ppa gene encoding inorganic pyrophosphatase: mutations in the ribosome-binding site decrease the level of ppa mRNA.
Journal of general microbiology 1991;137(11):2517-23.
1990: Maritta Perälä; Pirkko Vihko; M Södervall; J Heikkilä; RK Vihko
Biodistribution in normal mice of an 111In-labelled prostatic acid phosphatase-specific antibody and its F(ab')2 fragments derivatized site-specifically or via bicyclic diethylenetriaminepentaacetic acid anhydride.
European journal of nuclear medicine 1990;16(8-10):621-6.