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Roman Perez-Soler

Research Profile

Chemicals & Drugs

Disorders

Living Beings

Mouse

Anatomy

Tumor Cells, Cultured

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Physiology

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Procedures

Drug Screening Assays, Antitumor

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Publications

TOP 3
Yiyu Zou; Yi-He Ling; Roman Perez-Soler; Edward L Schwartz; Juan Sironi; Bilal Piperdi
The Autophagy Inhibitor Chloroquine Overcomes the Innate Resistance of Wild-Type EGFR Non-Small-Cell Lung Cancer Cells to Erlotinib.
Shaad E Abdullah; Roman Perez-Soler
Mechanisms of resistance to vascular endothelial growth factor blockade.
Bilal Piperdi; Roman Perez-Soler
Role of erlotinib in the treatment of non-small cell lung cancer: clinical outcomes in wild-type epidermal growth factor receptor patients.

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All Publications

2013: Yiyu Zou; Yi-He Ling; Roman Perez-Soler; Edward L Schwartz; Juan Sironi; Bilal Piperdi
The Autophagy Inhibitor Chloroquine Overcomes the Innate Resistance of Wild-Type EGFR Non-Small-Cell Lung Cancer Cells to Erlotinib.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013;8(6):693-702.
2012: Shaad E Abdullah; Roman Perez-Soler
Mechanisms of resistance to vascular endothelial growth factor blockade.
Cancer 2012;118(14):3455-67.
2012: Bilal Piperdi; Roman Perez-Soler
Role of erlotinib in the treatment of non-small cell lung cancer: clinical outcomes in wild-type epidermal growth factor receptor patients.
Drugs 2012;72 Suppl 1():11-9.
2012: Bilal Piperdi; William V Walsh; Zheng Zhou; Venu Bathini; Kendra Bradley; Meredith Hanrahan-Boshes; Lloyd Hutchinson; Roman Perez-Soler
Phase-I/II study of bortezomib in combination with carboplatin and bevacizumab as first-line therapy in patients with advanced non-small-cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012;7(6):1032-40.
2011: Bilal Piperdi; Leonard Liebes; Yi-He Ling; Franco Muggia; Roman Perez-Soler
Bortezomib: understanding the mechanism of action.
Molecular cancer therapeutics 2011;10(11):2029-30.
2011: Roman Perez-Soler; Yiyu Zou; Tianhong Li; Yi He Ling
The phosphatase inhibitor menadione (vitamin K3) protects cells from EGFR inhibition by erlotinib and cetuximab.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(21):6766-77.
2011: Yi-He Ling; Bo Lu; Miguel Aracil; Ana Maria Cuervo; José Jimeno; Ziqiang Yuan; Yiyu Zou; Roman Perez-Soler
PM02734 (elisidepsin) induces caspase-independent cell death associated with features of autophagy, inhibition of the Akt/mTOR signaling pathway, and activation of death-associated protein kinase.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(16):5353-66.
2011: Thomas M Harris; Qiulu Pan; Juan Sironi; Dionne Lutz; Jianmin Tian; Jana Sapkar; Roman Perez-Soler; Steven M Keller; Joseph Locker
Both gene amplification and allelic loss occur at 14q13.3 in lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(4):690-9.
2010: Sameer Mahesh; Ashish Saxena; Xuan Qiu; Roman Perez-Soler; Yiyu Zou
Intratracheally administered 5-azacytidine is effective against orthotopic human lung cancer xenograft models and devoid of important systemic toxicity.
Clinical lung cancer 2010;11(6):405-11.
2010: Roman Perez-Soler
EGFR TKIs for advanced NSCLC: practical questions.
Oncology (Williston Park, N.Y.) 2010;24(5):400-1, 409.
2010: Tianhong Li; Liawaty Ho; Bilal Piperdi; Tarek Elrafei; Fernando J Camacho; James R Rigas; Roman Perez-Soler; Rasim Gucalp
Phase II study of the proteasome inhibitor bortezomib (PS-341, Velcade) in chemotherapy-naïve patients with advanced stage non-small cell lung cancer (NSCLC).
Lung cancer (Amsterdam, Netherlands) 2010;68(1):89-93.
2010: Tianhong Li; Primo Lara; Philip C Mack; Roman Perez-Soler; David R Gandara
Intercalation of erlotinib and pemetrexed in the treatment of non-small cell lung cancer.
Current drug targets 2010;11(1):85-94.
2009: Roman Perez-Soler
Individualized therapy in non-small-cell lung cancer: future versus current clinical practice.
Oncogene 2009;28 Suppl 1():S38-45.
2009: Yi-He Ling; Tianhong Li; Roman Perez-Soler; Missak Haigentz
Activation of ER stress and inhibition of EGFR N-glycosylation by tunicamycin enhances susceptibility of human non-small cell lung cancer cells to erlotinib.
Cancer chemotherapy and pharmacology 2009;64(3):539-48.
2009: Yi-He Ling; Miguel Aracil; José Jimeno; Roman Perez-Soler; Yiyu Zou
Molecular pharmacodynamics of PM02734 (elisidepsin) as single agent and in combination with erlotinib; synergistic activity in human non-small cell lung cancer cell lines and xenograft models.
European journal of cancer (Oxford, England : 1990) 2009;45(10):1855-64.
2009: Tianhong Li; Roman Perez-Soler
Skin toxicities associated with epidermal growth factor receptor inhibitors.
Targeted oncology 2009;4(2):107-19.
2008: Yi-He Ling; Ruoping Lin; Roman Perez-Soler
Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK.
Molecular pharmacology 2008;74(3):793-806.
2008: Tianhong Li; Yi-He Ling; Roman Perez-Soler
Tumor dependence on the EGFR signaling pathway expressed by the p-EGFR:p-AKT ratio predicts erlotinib sensitivity in human non-small cell lung cancer (NSCLC) cells expressing wild-type EGFR gene.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(6):643-7.
2008: Minaxi Jhawer; SANJAY GOEL; Andrew J Wilson; Cristina Montagna; Yi-He Ling; Do-Sun Byun; Shannon Nasser; Diego Arango; Joongho Shin; Lidija Klampfer; Leonard H Augenlicht; Roman Perez-Soler; Roman Perez Soler; John M Mariadason
PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab.
Cancer research 2008;68(6):1953-61.
2007: Marie-Emmanuelle Legrier; Chia-Ping Huang Yang; Han-Guang Yan; Lluis Lopez-Barcons; Steven M Keller; Roman Perez-Soler; Susan B. Horwitz; Hayley M McDaid
Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression.
Cancer research 2007;67(23):11300-8.
2007: Roman Perez-Soler; Eric Van Cutsem
Clinical research of EGFR inhibitors and related dermatologic toxicities.
Oncology (Williston Park, N.Y.) 2007;21(11 Suppl 5):10-6.
2007: Edith P Mitchell; Roman Perez-Soler; Eric Van Cutsem; Mario Lacouture
Clinical presentation and pathophysiology of EGFRI dermatologic toxicities.
Oncology (Williston Park, N.Y.) 2007;21(11 Suppl 5):4-9.
2007: Yiyu Zou; Carmen Tornos; Xuan Qiu; Mariel Lia; Roman Perez-Soler
p53 aerosol formulation with low toxicity and high efficiency for early lung cancer treatment.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(16):4900-8.
2007: Bilal Piperdi; Yi-He Ling; Roman Perez-Soler
Schedule-dependent interaction between the proteosome inhibitor bortezomib and the EGFR-TK inhibitor erlotinib in human non-small cell lung cancer cell lines.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2007;2(8):715-21.
2007: Roman Perez-Soler
Erlotinib: recent clinical results and ongoing studies in non small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(15 Pt 2):s4589-92.
2007: Thomas J Lynch; Philip D Bonomi; Charles Butts; Angela M Davies; Jeffrey A Engelman; Ramaswamy Govindan; Roy S Herbst; John V Heymach; Bruce E Johnson; Renato G Martins; Roman Perez-Soler; Gregory J Riely; Alan B Sandler; Lecia V Sequist; Mark A Socinski; Kwok-Kin Wong; Carol S Hart
Novel agents in the treatment of lung cancer: Fourth Cambridge Conference.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(15 Pt 2):s4583-8.
2007: Yi-He Ling; Tianhong Li; Ziqiang Yuan; Missak Haigentz; Thomas K. Weber; Roman Perez-Soler
Erlotinib, an effective epidermal growth factor receptor tyrosine kinase inhibitor, induces p27KIP1 up-regulation and nuclear translocation in association with cell growth inhibition and G1/S phase arrest in human non-small-cell lung cancer cell lines.
Molecular pharmacology 2007;72(2):248-58.
2007: Tianhong Li; Yi-He Ling; I David Goldman; Roman Perez-Soler
Schedule-dependent cytotoxic synergism of pemetrexed and erlotinib in human non-small cell lung cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(11):3413-22.
2007: Bart P H Wittgen; Peter W A Kunst; Kasper van der Born; Atie W van Wijk; Walter Perkins; Frank G Pilkiewicz; Roman Perez-Soler; Susan Nicholson; Godefridus J Peters; Pieter E Postmus
Phase I study of aerosolized SLIT cisplatin in the treatment of patients with carcinoma of the lung.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(8):2414-21.
2007: SANJAY GOEL; Manuel Hidalgo; Roman Perez-Soler
EGFR inhibitor-mediated apoptosis in solid tumors.
Journal of experimental therapeutics & oncology 2007;6(4):305-20.
2006: Roman Perez-Soler
Rash as a surrogate marker for efficacy of epidermal growth factor receptor inhibitors in lung cancer.
Clinical lung cancer 2006;8 Suppl 1():S7-14.
2005: Charles Lu; Roman Perez-Soler; Bilal Piperdi; Garrett L Walsh; Stephen G Swisher; W Roy Smythe; Hyung J Shin; Jae Y Ro; Lei Feng; Mylene T Truong; Adiseshu Yalamanchili; Gabriel Lopez-Berestein; Waun Ki Hong; Abdul R Khokhar; Dong M Shin
Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with malignant pleural mesothelioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(15):3495-501.
2005: Roman Perez-Soler; Jean-Pierre Delord; Allan C Halpern; Karen Kelly; James Krueger; Bartomeu Massutí Sureda; Joachim von Pawel; Jennifer S Temel; Salvatore Siena; Denis Soulières; Leonard B Saltz; James Leyden
HER1/EGFR inhibitor-associated rash: future directions for management and investigation outcomes from the HER1/EGFR inhibitor rash management forum.
The oncologist 2005;10(5):345-56.
2005: Hayley M McDaid; Lluis Lopez-Barcons; Aaron Grossman; Mariel Lia; Steven M Keller; Roman Perez-Soler; Susan B. Horwitz
Enhancement of the therapeutic efficacy of taxol by the mitogen-activated protein kinase kinase inhibitor CI-1040 in nude mice bearing human heterotransplants.
Cancer research 2005;65(7):2854-60.
2005: Qun Dai; Yi-He Ling; Mariel Lia; Yiyu Zou; Glenn S Kroog; Kenneth K Iwata; Roman Perez-Soler
Enhanced sensitivity to the HER1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib hydrochloride in chemotherapy-resistant tumor cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(4):1572-8.
2004: Roman Perez-Soler
Phase II clinical trial data with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib (OSI-774) in non-small-cell lung cancer.
Clinical lung cancer 2004;6 Suppl 1():S20-3.
2004: Liang Hu; Merlin Lee; Wendy Campbell; Roman Perez-Soler; Simon Karpatkin
Role of endogenous thrombin in tumor implantation, seeding, and spontaneous metastasis.
Blood 2004;104(9):2746-51.
2004: Lluis Lopez-Barcons; Junhong Zhang; Gunching Siriwitayawan; Thomas G Burke; Roman Perez-Soler
The novel highly lipophilic topoisomerase I inhibitor DB67 is effective in the treatment of liver metastases of murine CT-26 colon carcinoma.
Neoplasia (New York, N.Y.) 2004;6(5):457-67.
2004: Roman Perez-Soler; Abraham Chachoua; Lisa A Hammond; Eric K Rowinsky; Mark S Huberman; Daniel Karp; James Rigas; Gary M Clark; Pedro Santabárbara; Philip Bonomi
Determinants of tumor response and survival with erlotinib in patients with non--small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(16):3238-47.
2004: Roman Perez-Soler
The role of erlotinib (Tarceva, OSI 774) in the treatment of non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(12 Pt 2):4238s-4240s.
2004: Thomas J Lynch; Alex A. Adjei; Paul A Bunn; Raymond DuBois; David R Gandara; Giuseppe Giaccone; Ramaswamy Govindan; Roy S Herbst; Bruce E Johnson; Fadlo R Khuri; Roman Perez-Soler; Rafael Rosell; Eric K Rowinsky; Alan B Sandler; Giorgio V Scagliotti; Joan H Schiller; Geoffrey I Shapiro; Mark A Socinski; Carol S Hart
Novel agents in the treatment of lung cancer: conference summary statement.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(12 Pt 2):4199s-4204s.
2004: Yun Zhong; Lluis Lopez-Barcons; Missak Haigentz; Yi-He Ling; Roman Perez-Soler
Exogenous expression of H-cadherin in CHO cells regulates contact inhibition of cell growth by inducing p21 expression.
International journal of oncology 2004;24(6):1573-9.
2004: Roberto Diaz; Lluis Lopez-Barcons; Daniel Ahn; Antonio Garcia-Espana; Andrew Yoon; Jeremy Matthews; Bafalluy Mangues; Roman Perez-Soler; Angel Pellicer
Complex effects of Ras proto-oncogenes in tumorigenesis.
Carcinogenesis 2004;25(4):535-9.
2004: Thomas J Belbin; John Gaspar; Missak Haigentz; Roman Perez-Soler; Steven M Keller; Michael B Prystowsky; Geoffrey Childs; Nicholas D Socci
Indirect measurements of differential gene expression with cDNA microarrays.
BioTechniques 2004;36(2):310-4.
2004: Katrina Y Glover; Roman Perez-Soler; Vassiliki A Papadimitradopoulou
A review of small-molecule epidermal growth factor receptor-specific tyrosine kinase inhibitors in development for non-small cell lung cancer.
Seminars in oncology 2004;31(1 Suppl 1):83-92.
2004: Roman Perez-Soler
HER1/EGFR targeting: refining the strategy.
The oncologist 2004;9(1):58-67.
2003: Roman Perez-Soler
Can rash associated with HER1/EGFR inhibition be used as a marker of treatment outcome?
Oncology (Williston Park, N.Y.) 2003;17(11 Suppl 12):23-8.
2003: Yi-He Ling; Leonard Liebes; Yiyu Zou; Roman Perez-Soler
Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells.
The Journal of biological chemistry 2003;278(36):33714-23.
2003: Marija Drobnjak; Jonathan Melamed; Samir Taneja; Kate Melzer; Rosemary Wieczorek; Benjamin Levinson; Anne Zeleniuch-Jacquotte; David Polsky; Jay Ferrara; Roman Perez-Soler; Carlos Cordon-Cardo; Michele Pagano; Iman Osman
Altered expression of p27 and Skp2 proteins in prostate cancer of African-American patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(7):2613-9.
2003: Anca Bulgaru; Sridhar Mani; SANJAY GOEL; Roman Perez-Soler
Erlotinib (Tarceva): a promising drug targeting epidermal growth factor receptor tyrosine kinase.
Expert review of anticancer therapy 2003;3(3):269-79.
2003: WenJing Liu; Anca Bulgaru; Missak Haigentz; Cy A Stein; Roman Perez-Soler; Sridhar Mani
The BCL2-family of protein ligands as cancer drugs: the next generation of therapeutics.
Current medicinal chemistry. Anti-cancer agents 2003;3(3):217-23.
2003: Yi-He Ling; Leonard Liebes; Jian-Dong Jiang; James F Holland; Peter J Elliott; Julian Adams; Franco M Muggia; Roman Perez-Soler
Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):1145-54.
2003: Missak Haigentz; Roman Perez-Soler
Chemopreventive therapeutics. Inhalation therapies for lung cancer and bronchial premalignancy.
Methods in molecular medicine 2003;75():771-80.
2002: Jian-Dong Jiang; Larry Denner; Yi-He Ling; Jian-Nong Li; Ashley Davis; Yue Wang; Yan Li; Julia Roboz; Long G Wang; Roman Perez-Soler; Marco Marcelli; George Bekesi; James F Holland
Double blockade of cell cycle at g(1)-s transition and m phase by 3-iodoacetamido benzoyl ethyl ester, a new type of tubulin ligand.
Cancer research 2002;62(21):6080-8.
2002: Yi-He Ling; Jian-Dong Jiang; James F Holland; Roman Perez-Soler
Arsenic trioxide produces polymerization of microtubules and mitotic arrest before apoptosis in human tumor cell lines.
Molecular pharmacology 2002;62(3):529-38.
2002: Yi-He Ling; Leonard Liebes; Bruce Ng; Michael Buckley; Peter J Elliott; Julian Adams; Jian-Dong Jiang; Franco M Muggia; Roman Perez-Soler
PS-341, a novel proteasome inhibitor, induces Bcl-2 phosphorylation and cleavage in association with G2-M phase arrest and apoptosis.
Molecular cancer therapeutics 2002;1(10):841-9.
2002: Roberto Diaz; Daniel Ahn; Lluis Lopez-Barcons; Marcos Malumbres; Ignacio Perez de Castro; Jeffrey Lue; Neus Ferrer-Miralles; Bafalluy Mangues; Jerry Tsong; Roberto Garcia; Roman Perez-Soler; Angel Pellicer
The N-ras proto-oncogene can suppress the malignant phenotype in the presence or absence of its oncogene.
Cancer research 2002;62(15):4514-8.
2002: SANJAY GOEL; Sridhar Mani; Roman Perez-Soler
Tyrosine kinase inhibitors: a clinical perspective.
Current oncology reports 2002;4(1):9-19.
2001: Yi-He Ling; Nicholas J Donato; Roman Perez-Soler
Sensitivity to topoisomerase I inhibitors and cisplatin is associated with epidermal growth factor receptor expression in human cervical squamous carcinoma ME180 sublines.
Cancer chemotherapy and pharmacology 2001;47(6):473-80.
2001: Y Zhong; Yara Delgado; Jorge Gomez; S W Lee; Roman Perez-Soler
Loss of H-cadherin protein expression in human non-small cell lung cancer is associated with tumorigenicity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(6):1683-7.
2001: Dong M Shin; Nicholas J Donato; Roman Perez-Soler; Hyung Ju C Shin; J Y Wu; P Zhang; KN Lawhorn; Fadlo R Khuri; Bonnie S Glisson; J Myers; Gary L Clayman; David G Pfister; J Falcey; Harlan W Waksal; John Mendelsohn; Waun Ki Hong
Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(5):1204-13.
2001: Yi-He Ling; Y Zhong; Roman Perez-Soler
Disruption of cell adhesion and caspase-mediated proteolysis of beta- and gamma-catenins and APC protein in paclitaxel-induced apoptosis.
Molecular pharmacology 2001;59(3):593-603.
2000: Roman Perez-Soler; B Kemp; Qing-Ping Wu; Li Mao; Jorge Gomez; Anne Zeleniuch-Jacquotte; Herman Yee; J S Lee; Jaishree Jagirdar; Yi-He Ling
Response and determinants of sensitivity to paclitaxel in human non-small cell lung cancer tumors heterotransplanted in nude mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(12):4932-8.
2000: Y Oh; Roman Perez-Soler; Frank V Fossella; Bonnie S Glisson; Jonathan M Kurie; Garrett L Walsh; Mylene T Truong; Dong M Shin
Phase II study of intravenous Doxil in malignant pleural mesothelioma.
Investigational new drugs 2000;18(3):243-5.
2000: Leslie E Fox; R C Rosenthal; R R King; P B Levine; David M Vail; Stuart C Helfand; E Gregory MacEwen; Roman Perez-Soler; M Calderwood-Mays; Ilene D Kurzman
Use of cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II), a liposomal cisplatin analogue, in cats with oral squamous cell carcinoma.
American journal of veterinary research 2000;61(7):791-5.
2000: DS Maclean; Abdul R Khokhar; Roman Perez-Soler
Neutron activation of NDDP, a liposomal platinum antitumor agent.
Cancer biotherapy & radiopharmaceuticals 2000;15(3):253-9.
2000: Yiyu Zou; G Zong; Yi-He Ling; Roman Perez-Soler
Development of cationic liposome formulations for intratracheal gene therapy of early lung cancer.
Cancer gene therapy 2000;7(5):683-96.
2000: DS Maclean; Abdul R Khokhar; P Tyle; Roman Perez-Soler
Intraliposomal chemical activation patterns of liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II) (L-NDDP)-a potential antitumour agent.
Journal of microencapsulation 2000;17(3):307-22.
2000: Nancy Yen; Constantin G Ioannides; Kai Xu; Stephen G Swisher; DD Lawrence; Bonnie L Kemp; Adel K El-Naggar; Richard J Cristiano; Bingliang Fang; Bonnie S Glisson; Waun Ki Hong; Fadlo R Khuri; Jonathan M Kurie; J J Lee; J S Lee; James A Merritt; Tapas Mukhopadhyay; Jonathan C Nesbitt; Dao Nguyen; Roman Perez-Soler; Katherine M W Pisters; Joe B Putnam; DS Schrump; Dong M Shin; Garrett L Walsh; Jack A Roth
Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type. P53 (Ad-p53).
Cancer gene therapy 2000;7(4):530-6.
2000: Yi-He Ling; Yiyu Zou; Roman Perez-Soler
Induction of senescence-like phenotype and loss of paclitaxel sensitivity after wild-type p53 gene transfection of p53-null human non-small cell lung cancer H358 cells.
Anticancer research 2000;20(2A):693-702.
2000: John Nemunaitis; Stephen G Swisher; T Timmons; D Connors; M Mack; L Doerksen; D Weill; J Wait; DD Lawrence; Bonnie L Kemp; Frank V Fossella; Bonnie S Glisson; Waun Ki Hong; Fadlo R Khuri; Jonathan M Kurie; J J Lee; J S Lee; Dao Nguyen; Jonathan C Nesbitt; Roman Perez-Soler; Katherine M W Pisters; Joe B Putnam; W R Richli; Dong M Shin; Garrett L Walsh; James Merritt; J Roth
Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(3):609-22.
2000: Daniel J Booser; Roman Perez-Soler; P Cossum; Laura Guerra; Qing-Ping Wu; Yiyu Zou; Waldemar Priebe; Gabriel N Hortobagyi
Phase I study of liposomal annamycin.
Cancer chemotherapy and pharmacology 2000;46(5):427-32.
2000: Nicholas J Donato; M Perez; H Kang; Zahid H Siddik; Yi-He Ling; Roman Perez-Soler
EGF receptor and p21WAF1 expression are reciprocally altered as ME-180 cervical carcinoma cells progress from high to low cisplatin sensitivity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(1):193-202.
1999: Bonnie S Glisson; Jonathan M Kurie; Roman Perez-Soler; N J Fox; WK Murphy; Frank V Fossella; Jin S Lee; M B Ross; D A Nyberg; Katherine M W Pisters; Dong M Shin; Waun Ki Hong
Cisplatin, etoposide, and paclitaxel in the treatment of patients with extensive small-cell lung carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(8):2309-15.
1999: S G Swisher; J A Roth; J Nemunaitis; D D Lawrence; B L Kemp; C H Carrasco; D G Connors; A K El-Naggar; F Fossella; B S Glisson; Waun Ki Hong; Fadlo R Khuri; J M Kurie; J J Lee; J S Lee; M Mack; J A Merritt; Dao Nguyen; J C Nesbitt; Roman Perez-Soler; K M Pisters; J B Putnam; W R Richli; M Savin; D S Schrump; Dong M Shin; A Shulkin; G L Walsh; J Wait; D Weill; M K Waugh
Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer.
Journal of the National Cancer Institute 1999;91(9):763-71.
1999: Leslie E Fox; K Toshach; M Calderwood-Mays; Abdul R Khokhar; Paul S Kubilis; Roman Perez-Soler; E Gregory MacEwen
Evaluation of toxicosis of liposome-encapsulated cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II) in clinically normal cats.
American journal of veterinary research 1999;60(2):257-63.
1998: Jian-Dong Jiang; A S Davis; Kim M Middleton; Yi-He Ling; Roman Perez-Soler; James F Holland; JG Bekesi
3-(Iodoacetamido)-benzoylurea: a novel cancericidal tubulin ligand that inhibits microtubule polymerization, phosphorylates bcl-2, and induces apoptosis in tumor cells.
Cancer research 1998;58(23):5389-95.
1998: Yi-He Ling; Y Yang; Carmen Tornos; Balraj Singh; Roman Perez-Soler
Paclitaxel-induced apoptosis is associated with expression and activation of c-Mos gene product in human ovarian carcinoma SKOV3 cells.
Cancer research 1998;58(16):3633-40.
1998: Yiyu Zou; G Zong; Yi-He Ling; M M Hao; G Lozano; Waun Ki Hong; Roman Perez-Soler
Effective treatment of early endobronchial cancer with regional administration of liposome-p53 complexes.
Journal of the National Cancer Institute 1998;90(15):1130-7.
1998: Yi-He Ling; Carmen Tornos; Roman Perez-Soler
Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.
The Journal of biological chemistry 1998;273(30):18984-91.
1998: Yi-He Ling; U Consoli; Carmen Tornos; Michael Andreeff; Roman Perez-Soler
Accumulation of cyclin B1, activation of cyclin B1-dependent kinase and induction of programmed cell death in human epidermoid carcinoma KB cells treated with taxol.
International journal of cancer. Journal international du cancer 1998;75(6):925-32.
1998: Juan Fueyo; Candelaria Gomez-Manzano; Vinay K Puduvalli; P Martin-Duque; Roman Perez-Soler; Victor Levin; W K Alfred Yung; Athanassios P Kyritsis
Adenovirus-mediated p16 transfer to glioma cells induces G1 arrest and protects from paclitaxel and topotecan: implications for therapy.
International journal of oncology 1998;12(3):665-9.
1998: Bonnie S Glisson; Ritsuko Komaki; Jin S Lee; Dong M Shin; Frank V Fossella; WK Murphy; Jonathan M Kurie; Roman Perez-Soler; RA Schea; Saroj Vadhan-Raj
Integration of filgrastim into chemoradiation for limited small cell lung cancer: a Phase I study.
International journal of radiation oncology, biology, physics 1998;40(2):331-6.
1998: Bonnie S Glisson; Jin S Lee; J Palmer; Frank V Fossella; Dong M Shin; WK Murphy; Roman Perez-Soler; Waun Ki Hong
Cisplatin, ifosfamide, and prolonged oral etoposide in the treatment of patients with extensive small cell lung carcinoma.
Cancer 1998;82(2):301-8.
1998: R J Shade; Katherine M W Pisters; M H Huber; Frank V Fossella; Roman Perez-Soler; Dong M Shin; Jonathan M Kurie; Bonnie S Glisson; S Lippman; J S Lee
Phase I study of paclitaxel administered by ten-day continuous infusion.
Investigational new drugs 1998;16(3):237-43.
1997: Roman Perez-Soler
Topotecan in the treatment of non-small cell lung cancer.
Seminars in oncology 1997;24(6 Suppl 20):S20-34-S20-41.
1997: Roman Perez-Soler; N Neamati; Yiyu Zou; E Schneider; L Austin Doyle; Michael Andreeff; Waldemar Priebe; Yi-He Ling
Annamycin circumvents resistance mediated by the multidrug resistance-associated protein (MRP) in breast MCF-7 and small-cell lung UMCC-1 cancer cell lines selected for resistance to etoposide.
International journal of cancer. Journal international du cancer 1997;71(1):35-41.
1997: Roman Perez-Soler; Dong M Shin; Zahid H Siddik; WK Murphy; M Huber; Sang-Joon Lee; Abdul R Khokhar; Waun Ki Hong
Phase I clinical and pharmacological study of liposome-entrapped NDDP administered intrapleurally in patients with malignant pleural effusions.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(3):373-9.
1997: Jonathan B Chaires; Fenfei Leng; Teresa Przewloka; Izabela Fokt; Yi-He Ling; Roman Perez-Soler; Waldemar Priebe
Structure-based design of a new bisintercalating anthracycline antibiotic.
Journal of medicinal chemistry 1997;40(3):261-6.
1997: Frank V Fossella; Scott M Lippman; Dong M Shin; P Tarassoff; M Calayag-Jung; Roman Perez-Soler; Jin S Lee; WK Murphy; Bonnie S Glisson; Edgardo Rivera; Waun Ki Hong
Maximum-tolerated dose defined for single-agent gemcitabine: a phase I dose-escalation study in chemotherapy-naive patients with advanced non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(1):310-6.
1996: Roman Perez-Soler; Bonnie S Glisson; Jin S Lee; Frank V Fossella; WK Murphy; Dong M Shin; Waun Ki Hong
Treatment of patients with small-cell lung cancer refractory to etoposide and cisplatin with the topoisomerase I poison topotecan.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(10):2785-90.
1996: U Consoli; Waldemar Priebe; Yi-He Ling; R Mahadevia; M Griffin; Shourong Zhao; Roman Perez-Soler; Michael Andreeff
The novel anthracycline annamycin is not affected by P-glycoprotein-related multidrug resistance: comparison with idarubicin and doxorubicin in HL-60 leukemia cell lines.
Blood 1996;88(2):633-44.
1996: Yi-He Ling; A K el-Naggar; Waldemar Priebe; Roman Perez-Soler
Cell cycle-dependent cytotoxicity, G2/M phase arrest, and disruption of p34cdc2/cyclin B1 activity induced by doxorubicin in synchronized P388 cells.
Molecular pharmacology 1996;49(5):832-41.
1996: Roman Perez-Soler; Frank V Fossella; Bonnie S Glisson; Jin S Lee; WK Murphy; Dong M Shin; Bonnie L Kemp; J Jack Lee; J Kane; R A Robinson; Scott M Lippman; Jonathan M Kurie; M H Huber; Martin N Raber; Waun Ki Hong
Phase II study of topotecan in patients with advanced non-small-cell lung cancer previously untreated with chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(2):503-13.
1996: Yiyu Zou; Waldemar Priebe; Roman Perez-Soler
Lyophilized preliposomal formulation of the non-cross-resistant anthracycline annamycin: effect of surfactant on liposome formation, stability and size.
Cancer chemotherapy and pharmacology 1996;39(1-2):103-8.
1996: I Han; Abdul R Khokhar; Roman Perez-Soler
Intraliposomal conversion of lipophilic cis-bis-carboxylato-trans-R,R-1,2-diaminocyclohexane-platinum (II) complexes into cis-bis-dichloro-trans-R,R-1,2-diaminocyclohexane-platinum (II).
Cancer chemotherapy and pharmacology 1996;39(1-2):17-24.
1996: M M Gaspar; Roman Perez-Soler; M E Cruz
Biological characterization of L-asparaginase liposomal formulations.
Cancer chemotherapy and pharmacology 1996;38(4):373-7.
1996: S M Sugarman; Yiyu Zou; K Wasan; K Poirot; R Kumi; S Reddy; Roman Perez-Soler
Lipid-complexed camptothecin: formulation and initial biodistribution and antitumor activity studies.
Cancer chemotherapy and pharmacology 1996;37(6):531-8.
1996: A Mori; S P Wu; I Han; A R Khokhar; Roman Perez-Soler; Leaf Huang
In vivo antitumor activity of cis-bis-neodecanoato-trans-R,R-1, 2-diaminocyclohexane platinum(II) formulated in long-circulating liposomes.
Cancer chemotherapy and pharmacology 1996;37(5):435-44.
1995: Yiyu Zou; W Priebe; L Clifton Stephens; Roman Perez-Soler
Preclinical toxicity of liposome-incorporated annamycin: selective bone marrow toxicity with lack of cardiotoxicity.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(11):1369-74.
1995: Kishor M Wasan; Roman Perez-Soler
Distribution of free and liposomal annamycin within human plasma is regulated by plasma triglyceride concentrations but not by lipid transfer protein.
Journal of pharmaceutical sciences 1995;84(9):1094-100.
1995: Yiyu Zou; Yi-He Ling; S Reddy; Waldemar Priebe; Roman Perez-Soler
Effect of vesicle size and lipid composition on the in vivo tumor selectivity and toxicity of the non-cross-resistant anthracycline annamycin incorporated in liposomes.
International journal of cancer. Journal international du cancer 1995;61(5):666-71.
1995: Yi-He Ling; Yiyu Zou; Waldemar Priebe; Roman Perez-Soler
Partial circumvention of multi-drug resistance by annamycin is associated with comparable inhibition of DNA synthesis in the nuclear matrix of sensitive and resistant cells.
International journal of cancer. Journal international du cancer 1995;61(3):402-8.
1995: Frank V Fossella; Jin S Lee; Dong M Shin; M Calayag; M Huber; Roman Perez-Soler; WK Murphy; Scott M Lippman; S Benner; Bonnie S Glisson
Phase II study of docetaxel for advanced or metastatic platinum-refractory non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(3):645-51.
1995: S Li; A R Khokhar; Roman Perez-Soler; Leaf Huang
Improved antitumor activity of cis-Bis-neodecanoato-trans-R,R-1,2- diaminocyclohexaneplatinum (II) entrapped in long-circulating liposomes.
Oncology research 1995;7(12):611-7.
1994: Eric Solary; Yi-He Ling; Roman Perez-Soler; Waldemar Priebe; Yves Pommier
Hydroxyrubicin, a deaminated derivative of doxorubicin, inhibits mammalian DNA topoisomerase II and partially circumvents multidrug resistance.
International journal of cancer. Journal international du cancer 1994;58(1):85-94.
1994: F Sampedro; J Partika; P Santalo; Antoni M. Molins; J Bonal; Roman Perez-Soler
Liposomes as carriers of different new lipophilic antitumour drugs: a preliminary report.
Journal of microencapsulation 1994;11(3):309-18.
1994: Roman Perez-Soler; Nicholas J Donato; Dong M Shin; Michael G Rosenblum; Hua-Zhong Zhang; C Tornos; H Brewer; J C Chan; Jin S Lee; Waun Ki Hong
Tumor epidermal growth factor receptor studies in patients with non-small-cell lung cancer or head and neck cancer treated with monoclonal antibody RG 83852.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(4):730-9.
1994: Yiyu Zou; Yi-He Ling; NT Van; Waldemar Priebe; Roman Perez-Soler
Antitumor activity of free and liposome-entrapped annamycin, a lipophilic anthracycline antibiotic with non-cross-resistance properties.
Cancer research 1994;54(6):1479-84.
1994: I Han; Yi-He Ling; Abdul R Khokhar; Roman Perez-Soler
Cell death and DNA fragmentation induced by liposomal platinum(II) complex, L-NDDP in A2780 and A2780/PDD cells.
Anticancer research 1994;14(2A):421-6.
1994: I Han; T Nguyen; L Y Yang; Abdul R Khokhar; Roman Perez-Soler
Cellular accumulation and DNA damage induced by liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum+ ++(II) in LoVo and LoVo/PDD cells.
Anti-cancer drugs 1994;5(1):64-8.
1994: Roman Perez-Soler; I Han; S al-Baker; Abdul R Khokhar
Lipophilic platinum complexes entrapped in liposomes: improved stability and preserved antitumor activity with complexes containing linear alkyl carboxylato leaving groups.
Cancer chemotherapy and pharmacology 1994;33(5):378-84.
1994: Roman Perez-Soler; Yi-He Ling; Yiyu Zou; Waldemar Priebe
Cellular pharmacology of the partially non-cross-resistant anthracycline annamycin entrapped in liposomes in KB and KB-V1 cells.
Cancer chemotherapy and pharmacology 1994;34(2):109-18.
1994: Roman Perez-Soler; K Francis; S al-Baker; F Pilkiewicz; Abdul R Khokhar
Preparation and characterization of liposomes containing a lipophilic cisplatin derivative for clinical use.
Journal of microencapsulation 1994;11(1):41-54.
1994: J C Jorge; Roman Perez-Soler; J G Morais; M E Cruz
Liposomal palmitoyl-L-asparaginase: characterization and biological activity.
Cancer chemotherapy and pharmacology 1994;34(3):230-4.
1994: Dong M Shin; P Y Holoye; A Forman; Rodger Winn; Roman Perez-Soler; Shaker R Dakhil; J Rosenthal; Martin N Raber; Waun Ki Hong
Phase II clinical trial of didemnin B in previously treated small cell lung cancer.
Investigational new drugs 1994;12(3):243-9.
1993: Y Ling; W Priebe; Roman Perez-Soler
Intrinsic cytotoxicity and reversal of multidrug-resistance by monensin in kb parent and mdr cells.
International journal of oncology 1993;3(5):971-7.
1993: Yiyu Zou; A Hayman; W Priebe; Roman Perez-Soler
Quantitative analysis of the lipophilic doxorubicin analogue annamycin in plasma and tissue samples by reversed-phase chromatography.
Journal of pharmaceutical sciences 1993;82(11):1151-4.
1993: W Priebe; Roman Perez-Soler
Design and tumor targeting of anthracyclines able to overcome multidrug resistance: a double-advantage approach.
Pharmacology & therapeutics 1993;60(2):215-34.
1993: I Han; Yi-He Ling; S al-Baker; Abdul R Khokhar; Roman Perez-Soler
Cellular pharmacology of liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum(II) in A2780/S and A2780/PDD cells.
Cancer research 1993;53(20):4913-9.
1993: Yi-He Ling; Roman Perez-Soler; M T Tseng
Effect of DNA topoisomerase I inhibitor, 10-hydroxycamptothecin, on the structure and function of nuclei and nuclear matrix in bladder carcinoma MBT-2 cells.
Anticancer research 1993;13(5A):1613-7.
1993: Yiyu Zou; M Yamagishi; I Horikoshi; Masaharu Ueno; X Gu; Roman Perez-Soler
Enhanced therapeutic effect against liver W256 carcinosarcoma with temperature-sensitive liposomal adriamycin administered into the hepatic artery.
Cancer research 1993;53(13):3046-51.
1993: Yi-He Ling; Waldemar Priebe; Roman Perez-Soler
Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells.
Cancer research 1993;53(8):1845-52.
1993: Yi-He Ling; Waldemar Priebe; Li-Ying Yang; T G Burke; Y Pommier; Roman Perez-Soler
In vitro cytotoxicity, cellular pharmacology, and DNA lesions induced by annamycin, an anthracycline derivative with high affinity for lipid membranes.
Cancer research 1993;53(7):1583-9.
1993: Waldemar Priebe; NT Van; T G Burke; Roman Perez-Soler
Removal of the basic center from doxorubicin partially overcomes multidrug resistance and decreases cardiotoxicity.
Anti-cancer drugs 1993;4(1):37-48.
1993: Yiyu Zou; Waldemar Priebe; Yi-He Ling; Roman Perez-Soler
Organ distribution and tumor uptake of annamycin, a new anthracycline derivative with high affinity for lipid membranes, entrapped in multilamellar vesicles.
Cancer chemotherapy and pharmacology 1993;32(3):190-6.
1993: Yiyu Zou; I Horikoshi; T Kasagi; X Gu; Roman Perez-Soler
Organ distribution and antitumor activity of free and liposomal doxorubicin injected into the hepatic artery.
Cancer chemotherapy and pharmacology 1993;31(4):313-8.
1992: Roman Perez-Soler; Abdul R Khokhar
Lipophilic cisplatin analogues entrapped in liposomes: role of intraliposomal drug activation in biological activity.
Cancer research 1992;52(22):6341-7.
1992: S al-Baker; Roman Perez-Soler; Abdul R Khokhar
Synthesis and biological studies of new lipid-soluble cisplatin analogues entrapped in liposomes.
Journal of inorganic biochemistry 1992;47(2):99-108.
1992: Yiyu Zou; I Horikoshi; Masaharu Ueno; X Gu; Roman Perez-Soler
Targeting liver tumors by administering liposomal doxorubicin into the hepatic artery.
International journal of cancer. Journal international du cancer 1992;51(2):232-7.
1992: Abdul R Khokhar; S al-Baker; Roman Perez-Soler
Toxicity and efficacy studies on a series of lipid-soluble dineodecanoato(trans-R,R- and trans-S,S-1,2-diaminocyclohexane) platinum (II) complexes entrapped in liposomes.
Anti-cancer drugs 1992;3(2):95-100.
1992: Waldemar Priebe; N Neamati; Roman Perez-Soler
3'-Hydroxyesorubicin halogenated at C-2'.
The Journal of antibiotics 1992;45(3):386-93.
1992: Roman Perez-Soler; Waldemar Priebe
Liposomal formulation and antitumor activity of 14-O-palmitoyl-hydroxyrubicin.
Cancer chemotherapy and pharmacology 1992;30(4):267-71.
1992: K Vadiei; Zahid H Siddik; Abdul R Khokhar; S al-Baker; F Sampedro; Roman Perez-Soler
Pharmacokinetics of liposome-entrapped cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II) and cisplatin given i.v. and i.p. in the rat.
Cancer chemotherapy and pharmacology 1992;30(5):365-9.
1992: S M Sugarman; Roman Perez-Soler
Liposomes in the treatment of malignancy: a clinical perspective.
Critical reviews in oncology/hematology 1992;12(3):231-42.
1991: K Vadiei; G Lopez-Berestein; Roman Perez-Soler; D R Luke
Tissue distribution and in vivo immunosuppressive activity of liposomal cyclosporine.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(6):1147-51.
1991: Abdul R Khokhar; S al-Baker; T Brown; Roman Perez-Soler
Chemical and biological studies on a series of lipid-soluble (trans-(R,R)- and -(S,S)-1,2-diaminocyclohexane)platinum(II) complexes incorporated in liposomes.
Journal of medicinal chemistry 1991;34(1):325-9.
1990: Roman Perez-Soler; Gabriel Lopez-Berestein; J Lautersztain; S al-Baker; K Francis; D Macias-Kiger; Martin N Raber; Abdul R Khokhar
Phase I clinical and pharmacological study of liposome-entrapped cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II).
Cancer research 1990;50(14):4254-9.
1990: Roman Perez-Soler; Waldemar Priebe
Anthracycline antibiotics with high liposome entrapment: structural features and biological activity.
Cancer research 1990;50(14):4260-6.
1990: Waldemar Priebe; N Neamati; Roman Perez-Soler
3'-Hydroxyesorubicin. Synthesis and antitumor activity.
The Journal of antibiotics 1990;43(7):838-46.
1989: Roman Perez-Soler
Liposomes as carriers of antitumor agents: toward a clinical reality.
Cancer treatment reviews 1989;16(2):67-82.
1989: Roman Perez-Soler; J Lautersztain; L Clifton Stephens; K Wright; Abdul R Khokhar
Preclinical toxicity and pharmacology of liposome-entrapped cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II).
Cancer chemotherapy and pharmacology 1989;24(1):1-8.
1989: Abdul R Khokhar; S al-Baker; I H Krakoff; Roman Perez-Soler
Toxicity and antitumor activity of cis-bis-carboxylato(trans-R,R-1,2-diaminocyclohexane) platinum(II) complexes entrapped in liposomes.
Cancer chemotherapy and pharmacology 1989;23(4):219-24.
1988: Abdul R Khokhar; S Al-Baker; Roman Perez-Soler
Toxicity and anti-tumor activity of hydrophobic diammine and diaminocyclohexane platinum complexes entrapped in multilamellar vesicles.
Anti-cancer drug design 1988;3(3):177-84.
1988: Roman Perez-Soler; L Y Yang; B Drewinko; J Lauterzstain; Abdul R Khokhar
Increased cytotoxicity and reversal of resistance to cis-diamminedichloro-platinum(II) with entrapment of cis-Bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum (II) in multilamellar lipid vesicles.
Cancer research 1988;48(16):4509-12.
1988: J Lautersztain; Roman Perez-Soler; J Turpin; Abdul R Khokhar; Z H Siddik; K Schmidt; Gabriel Lopez-Berestein
Cellular pharmacology of liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum (II) in mouse resident peritoneal macrophages, Kupffer cells, and hepatocytes.
Cancer research 1988;48(5):1300-6.
1988: Abdul R Khokhar; K Wright; Zahid H Siddik; Roman Perez-Soler
Organ distribution and tumor uptake of liposome entrapped cis-bis-neodecanoato trans-R, R-1,2 diaminocyclohexane platinum (II) administered intravenously and into the proper hepatic artery.
Cancer chemotherapy and pharmacology 1988;22(3):223-7.
1987: Roman Perez-Soler; Abdul R Khokhar; Gabriel Lopez-Berestein
Treatment and prophylaxis of experimental liver metastases of M5076 reticulosarcoma with cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum (II) encapsulated in multilamellar vesicles.
Cancer research 1987;47(24 Pt 1):6462-6.
1987: Roman Perez-Soler; Abdul R Khokhar; J Lautersztain; P A Mitchell; K L Schmidt
Ultrastructural and freeze fracture localization of multilamellar liposomes containing a lipophilic cisplatin analogue in normal tissues and liver metastases of M5076 reticulosarcoma.
Cancer drug delivery 1987;4(2):75-88.
1986: Roman Perez-Soler; A R Khokhar; M P Hacker; G Lopez-Berestein
Toxicity and antitumor activity of cis-bis-cyclopentenecarboxylato-1,2-diaminocyclohexane platinum(II) encapsulated in multilamellar vesicles.
Cancer research 1986;46(12 Pt 1):6269-73.
1986: Roman Perez-Soler; A R Khokhar; P Claringbold; L P Kasi; G Lopez-Berestein
Effects on the monocyte-macrophage system and antitumor activity against L1210 leukemia of cis-bis-cyclopentenecarboxylato-trans-R,R-1,2-diaminocyclohexane -platinum (II) encapsulated in multilamellar vesicles.
Journal of the National Cancer Institute 1986;77(5):1137-43.
1986: Roman Perez-Soler; T L Smith; F Cabanillas
Central nervous system prophylaxis with combined intravenous and intrathecal methotrexate in diffuse lymphoma of aggressive histologic type.
Cancer 1986;57(5):971-7.
1986: J Lautersztain; Roman Perez-Soler; Abdul R Khokhar; R A Newman; Gabriel Lopez-Berestein
Pharmacokinetics and tissue distribution of liposome-encapsulated cis-bis-N-decyl-iminodiacetato-1,2-diaminocyclohexane-platinum (II).
Cancer chemotherapy and pharmacology 1986;18(2):93-7.
1986: J L Murray; Roman Perez-Soler; D Bywaters; Evan M Hersh
Decreased adenosine deaminase (ADA) and 5'nucleotidase (5NT) activity in peripheral blood T cells in Hodgkin disease.
American journal of hematology 1986;21(1):57-66.
1985: Roman Perez-Soler; R Esteban; E Allende; C Tornos Salomo; A Julia; J Guardia
Liver involvement in multiple myeloma.
American journal of hematology 1985;20(1):25-9.
1985: Roman Perez-Soler; G Lopez-Berestein; L P Kasi; F Cabanillas; M Jahns; H Glenn; Evan M Hersh; T Haynie
Distribution of technetium-99m-labeled multilamellar liposomes in patients with Hodgkin's disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1985;26(7):743-9.
1985: Roman Perez-Soler; G Lopez-Berestein; F Cabanillas; P McLaughlin; Evan M Hersh
Superoxide anion (O-2) production by peripheral blood monocytes in Hodgkin's disease and malignant lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1985;3(5):641-5.
1985: Roman Perez-Soler; G Lopez-Berestein; M Jahns; K Wright; L P Kasi
Distribution of radiolabeled multilamellar liposomes injected intralymphatically and subcutaneously.
International journal of nuclear medicine and biology 1985;12(4):261-6.
1984: Roman Perez-Soler; P McLaughlin; W S Velasquez; F B Hagemeister; J Zornoza; J T Manning; L M Fuller; F Cabanillas
Clinical features and results of management of superior vena cava syndrome secondary to lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1984;2(4):260-6.
1984: M Butí; Roman Perez-Soler; M Cervantes; C Ruiz-Marcellan; J Genescá; R Esteban; J Guardia
[Pleuropulmonary involvement as the only manifestation of Waldenström's macroglobulinemia].
Medicina clínica 1984;82(7):320-2.
1984: J Merino; Roman Perez-Soler; M Luna; F Cabanillas
Benign fibrous histiocytoma in Hodgkin's disease.
Cancer investigation 1984;2(5):347-50.
1983: Roman Perez-Soler; M A Sanz Alonso; A Jaén Campos; C Tornos Salomó; J Martínez Domínguez; R Esteban Mur; J Guardia Massó; J Triginer Boixeda
[Tuberculosis and pseudoleukemia: study of 4 patients].
Medicina clínica 1983;80(20):884-7.
1981: Roman Perez-Soler; M Cervantes; R M Segura; R Esteban; C Pascual; J Guardia
Serum glutamate dehydrogenase in alcoholic liver disease.
British medical journal (Clinical research ed.) 1981;283(6302):1332.
1981: Roman Perez-Soler; R Esteban; J Guardia
Urinary monoclonal immunoglobulin in multiple myeloma.
Annals of internal medicine 1981;94(1):140.
1980: M P Tornos; Roman Perez-Soler; R Fernandez-Perez
Resection for carcinoma of the lung with metastases.
Chest 1980;77(5):713.