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Marianela Perez-Torres

Research Profile

Chemicals & Drugs

Anatomy

Tumor Cell Line

Living Beings

Physiology

Procedures

Xenograft Model Antitumor Assays

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Publications

TOP 3
Marianela Perez-Torres; Blanca L Valle; Nita Maihle; Lisandra Negron-Vega; Rene Nieves-Alicea; Elsa M Cora
Shedding of epidermal growth factor receptor is a regulated process that occurs with overexpression in malignant cells.
Christoph A Ritter; Marianela Perez-Torres; Cammie Rinehart; Marta Guix; Teresa Dugger; Jeffrey A Engelman; Carlos L Arteaga
Human breast cancer cells selected for resistance to trastuzumab in vivo overexpress epidermal growth factor receptor and ErbB ligands and remain dependent on the ErbB receptor network.
Marianela Perez-Torres; Marta Guix; Adriana Gonzalez; Carlos L Arteaga
Epidermal growth factor receptor (EGFR) antibody down-regulates mutant receptors and inhibits tumors expressing EGFR mutations.

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All Publications

2008: Marianela Perez-Torres; Blanca L Valle; Nita Maihle; Lisandra Negron-Vega; Rene Nieves-Alicea; Elsa M Cora
Shedding of epidermal growth factor receptor is a regulated process that occurs with overexpression in malignant cells.
Experimental cell research 2008;314(16):2907-18.
2007: Christoph A Ritter; Marianela Perez-Torres; Cammie Rinehart; Marta Guix; Teresa Dugger; Jeffrey A Engelman; Carlos L Arteaga
Human breast cancer cells selected for resistance to trastuzumab in vivo overexpress epidermal growth factor receptor and ErbB ligands and remain dependent on the ErbB receptor network.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(16):4909-19.
2006: Marianela Perez-Torres; Marta Guix; Adriana Gonzalez; Carlos L Arteaga
Epidermal growth factor receptor (EGFR) antibody down-regulates mutant receptors and inhibits tumors expressing EGFR mutations.
The Journal of biological chemistry 2006;281(52):40183-92.
2006: Shizhen Emily Wang; Archana Narasanna; Marianela Perez-Torres; Bin Xiang; Frederick Y Wu; seungchan yang; Graham Carpenter; Adi F Gazdar; Senthil K Muthuswamy; Carlos L Arteaga
HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors.
Cancer cell 2006;10(1):25-38.

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