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Daniel Perez

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Chemicals & Drugs

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Leukocyte Chemotaxis

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Anthony T Reder; Sharlene Velichko; Ken D Yamaguchi; Kemal Hamamcioglu; Karin Ku; Johanna Beekman; T Charis Wagner; H Daniel Perez; Hugh Salamon; Ed Croze
IFN-beta1b induces transient and variable gene expression in relapsing-remitting multiple sclerosis patients independent of neutralizing antibodies or changes in IFN receptor RNA expression.
Gerard Bannenberg; Rose-Laure Moussignac; Karsten Gronert; Pallavi R Devchand; Birgitta A Schmidt; William J Guilford; John G Bauman; Babu Subramanyam; H Daniel Perez; John Parkinson; Charles N Serhan
Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration.
Arndt Schottelius; Claudia Giesen; Khusru Asadullah; Iolanda M Fierro; Sean P Colgan; John G Bauman; William J Guilford; H Daniel Perez; John Parkinson
An aspirin-triggered lipoxin A4 stable analog displays a unique topical anti-inflammatory profile.

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2008: Anthony T Reder; Sharlene Velichko; Ken D Yamaguchi; Kemal Hamamcioglu; Karin Ku; Johanna Beekman; T Charis Wagner; H Daniel Perez; Hugh Salamon; Ed Croze
IFN-beta1b induces transient and variable gene expression in relapsing-remitting multiple sclerosis patients independent of neutralizing antibodies or changes in IFN receptor RNA expression.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2008;28(5):317-31.
2004: Gerard Bannenberg; Rose-Laure Moussignac; Karsten Gronert; Pallavi R Devchand; Birgitta A Schmidt; William J Guilford; John G Bauman; Babu Subramanyam; H Daniel Perez; John Parkinson; Charles N Serhan
Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration.
British journal of pharmacology 2004;143(1):43-52.
2002: Arndt Schottelius; Claudia Giesen; Khusru Asadullah; Iolanda M Fierro; Sean P Colgan; John G Bauman; William J Guilford; H Daniel Perez; John Parkinson
An aspirin-triggered lipoxin A4 stable analog displays a unique topical anti-inflammatory profile.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(12):7063-70.
2002: T Charis Wagner; Sharlene Velichko; David Vogel; M R Sandhya Rani; Stewart Leung; Richard M Ransohoff; George R Stark; H Daniel Perez; Ed Croze
Interferon signaling is dependent on specific tyrosines located within the intracellular domain of IFNAR2c. Expression of IFNAR2c tyrosine mutants in U5A cells.
The Journal of biological chemistry 2002;277(2):1493-9.
2001: Richard Horuk; S Shurey; Howard P Ng; K May; John G Bauman; Imadul Islam; Ameen Ghannam; Brad Buckman; Guo-Ping Wei; Wei Xu; Meina Liang; Mary Rosser; Laura Dunning; Joseph Hesselgesser; RM Snider; Michael M Morrissey; H Daniel Perez; C Green
CCR1-specific non-peptide antagonist: efficacy in a rabbit allograft rejection model.
Immunology letters 2001;76(3):193-201.
2001: Richard Horuk; C Clayberger; Alan Krensky; Z Wang; H J Grone; C Weber; Kim S C Weber; Peter J Nelson; K May; Mary Rosser; Laura Dunning; Meina Liang; Brad Buckman; Ameen Ghannam; Howard P Ng; Imadul Islam; John G Bauman; Guo-Ping Wei; S Monahan; Wei Xu; RM Snider; Michael M Morrissey; Joseph Hesselgesser; H Daniel Perez
A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection.
The Journal of biological chemistry 2001;276(6):4199-204.
2000: Ed Croze; Anna Usacheva; D Asarnow; Richard D Minshall; H Daniel Perez; Oscar R Colamonici
Receptor for activated C-kinase (RACK-1), a WD motif-containing protein, specifically associates with the human type I IFN receptor.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):5127-32.
2000: D Russell-Harde; T Charis Wagner; M R Sandhya Rani; David Vogel; Oscar R Colamonici; Richard M Ransohoff; Beata Majchrzak; Eleanor N Fish; H Daniel Perez; Ed Croze
Role of the intracellular domain of the human type I interferon receptor 2 chain (IFNAR2c) in interferon signaling. Expression of IFNAR2c truncation mutants in U5A cells.
The Journal of biological chemistry 2000;275(31):23981-5.
2000: Harald Dinter; J Tse; Meredith Halks-Miller; D Asarnow; James Onuffer; D Faulds; B Mitrovic; G Kirsch; H Laurent; Peter Esperling; Dieter Seidelmann; Eckhard Ottow; H Schneider; V K Tuohy; H Wachtel; H Daniel Perez
The type IV phosphodiesterase specific inhibitor mesopram inhibits experimental autoimmune encephalomyelitis in rodents.
Journal of neuroimmunology 2000;108(1-2):136-46.
2000: Meina Liang; Cornell Mallari; Mary Rosser; Howard P Ng; K May; S Monahan; John G Bauman; Imadul Islam; Ameen Ghannam; Brad Buckman; K Shaw; Guo-Ping Wei; Wei Xu; Z Zhao; E Ho; J Shen; H Oanh; Babu Subramanyam; Ronald Vergona; D Taub; Laura Dunning; S Harvey; RM Snider; Joseph Hesselgesser; Michael M Morrissey; H Daniel Perez
Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1.
The Journal of biological chemistry 2000;275(25):19000-8.
2000: NG Miyamoto; P S Medberry; Joseph Hesselgesser; S Boehlk; Peter J Nelson; Alan Krensky; H Daniel Perez
Interleukin-1beta induction of the chemokine RANTES promoter in the human astrocytoma line CH235 requires both constitutive and inducible transcription factors.
Journal of neuroimmunology 2000;105(1):78-90.
2000: Meina Liang; Mary Rosser; Howard P Ng; K May; John G Bauman; Imadul Islam; Ameen Ghannam; P J Kretschmer; H Pu; Laura Dunning; RM Snider; Michael M Morrissey; Joseph Hesselgesser; H Daniel Perez; Richard Horuk
Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor.
European journal of pharmacology 2000;389(1):41-9.
1999: Howard P Ng; K May; John G Bauman; Ameen Ghannam; Imadul Islam; Meina Liang; Richard Horuk; Joseph Hesselgesser; RM Snider; H Daniel Perez; Michael M Morrissey
Discovery of novel non-peptide CCR1 receptor antagonists.
Journal of medicinal chemistry 1999;42(22):4680-94.
1999: D Russell-Harde; T Charis Wagner; H Daniel Perez; Ed Croze
Formation of a uniquely stable type I interferon receptor complex by interferon beta is dependent upon particular interactions between interferon beta and its receptor and independent of tyrosine phosphorylation.
Biochemical and biophysical research communications 1999;255(2):539-44.
1998: DA Barnes; M Huston; H Daniel Perez
TNF-alpha and IL-1beta cross-desensitization of astrocytes and astrocytoma cell lines.
Journal of neuroimmunology 1998;87(1-2):17-26.
1998: Joseph Hesselgesser; Howard P Ng; Meina Liang; W Zheng; K May; John G Bauman; S Monahan; Imadul Islam; Guo-Ping Wei; Ameen Ghannam; D D Taub; Mary Rosser; RM Snider; Michael M Morrissey; H Daniel Perez; Richard Horuk
Identification and characterization of small molecule functional antagonists of the CCR1 chemokine receptor.
The Journal of biological chemistry 1998;273(25):15687-92.
1998: DA Barnes; J Tse; M Kaufhold; M Owen; Joseph Hesselgesser; R Strieter; Richard Horuk; H Daniel Perez
Polyclonal antibody directed against human RANTES ameliorates disease in the Lewis rat adjuvant-induced arthritis model.
The Journal of clinical investigation 1998;101(12):2910-9.
1997: Richard Horuk; Alvin W Martin; Zixuan Wang; Laura Schweitzer; A Gerassimides; H Guo; Z Lu; Joseph Hesselgesser; H Daniel Perez; J Kim; J Parker; Terence Hadley; Stephen Peiper
Expression of chemokine receptors by subsets of neurons in the central nervous system.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(6):2882-90.
1997: Harald Dinter; G Stock; H Daniel Perez
Multiple sclerosis: pathogenesis and models.
Journal of molecular medicine (Berlin, Germany) 1997;75(3):164.
1997: Harald Dinter; James Onuffer; D Faulds; H Daniel Perez
Phosphodiesterase type IV inhibitors in the treatment of multiple sclerosis.
Journal of molecular medicine (Berlin, Germany) 1997;75(2):95-102.
1997: B Mitrovic; G Stock; H Daniel Perez
Multiple sclerosis: from rags to riches.
Journal of molecular medicine (Berlin, Germany) 1997;75(2):75-6.
1997: DA Barnes; S W Jones; H Daniel Perez
High throughput screening for identification of RANTES chemokine expression inhibitors.
Methods in enzymology 1997;287():292-304.
1996: D A Barnes; M Huston; R Holmes; Etty N Benveniste; V W Yong; P Scholz; H Daniel Perez
Induction of RANTES expression by astrocytes and astrocytoma cell lines.
Journal of neuroimmunology 1996;71(1-2):207-14.
1994: H Daniel Perez; L Vilander; W H Andrews; R Holmes
Human formyl peptide receptor ligand binding domain(s). Studies using an improved mutagenesis/expression vector reveal a novel mechanism for the regulation of receptor occupancy.
The Journal of biological chemistry 1994;269(36):22485-7.
1993: H Daniel Perez; R Holmes; L R Vilander; R R Adams; W Manzana; D Jolley; W H Andrews
Formyl peptide receptor chimeras define domains involved in ligand binding.
The Journal of biological chemistry 1993;268(4):2292-5.
1992: H Daniel Perez; R Holmes; E Kelly; J McClary; Q Chou; W H Andrews
Cloning of the gene coding for a human receptor for formyl peptides. Characterization of a promoter region and evidence for polymorphic expression.
Biochemistry 1992;31(46):11595-9.
1992: H Daniel Perez; R Holmes; E Kelly; J McClary; W H Andrews
Cloning of a cDNA encoding a receptor related to the formyl peptide receptor of human neutrophils.
Gene 1992;118(2):303-4.
1992: F J Roll; H Daniel Perez; C N Serhan
Characterization of a novel arachidonic acid-derived neutrophil chemoattractant.
Biochemical and biophysical research communications 1992;186(1):269-76.
1992: H Daniel Perez; E Kelly; R Holmes
Regulation of formyl peptide receptor expression and its mRNA levels during differentiation of HL-60 cells.
The Journal of biological chemistry 1992;267(1):358-63.
1991: F J Roll; M A Alexander; D Cua; W Swanson; H Daniel Perez
Metabolism of ethanol by rat hepatocytes results in generation of a lipid chemotactic factor: studies using a cell-free system and role of oxygen-derived free radicals.
Archives of biochemistry and biophysics 1991;287(2):218-24.
1991: H Daniel Perez; E Kelly; F Elfman; G Armitage; J Winkler
Defective polymorphonuclear leukocyte formyl peptide receptor(s) in juvenile periodontitis.
The Journal of clinical investigation 1991;87(3):971-6.
1990: Errol Lobo; F Elfman; E Kelly; H Daniel Perez
Effect of phorbol myristate acetate on processing of formyl peptide receptors by human neutrophils.
Biochimica et biophysica acta 1990;1055(2):193-6.
1989: R Kurrasch; F Elfman; H Daniel Perez
Polymorphonuclear leukocytes cap a derivative of wheat germ agglutinin upon stimulation with formyl peptide and C5a but not leukotriene B4.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(6):1969-73.
1989: H Daniel Perez; F Elfman; S Marder; Errol Lobo; Harlan E Ives
Formyl peptide-induced chemotaxis of human polymorphonuclear leukocytes does not require either marked changes in cytosolic calcium or specific granule discharge. Role of formyl peptide receptor reexpression (or recycling).
The Journal of clinical investigation 1989;83(6):1963-70.
1989: F J Roll; M Alexander; H Daniel Perez
Generation of chemotactic activity for neutrophils by liver cells metabolizing ethanol.
Free radical biology & medicine 1989;7(5):549-55.
1988: H Daniel Perez; E Kelly; D Chenoweth; F Elfman
Identification of the C5a des Arg cochemotaxin. Homology with vitamin D-binding protein (group-specific component globulin).
The Journal of clinical investigation 1988;82(1):360-3.
1988: H Daniel Perez; E Kelly; D Chenoweth; F Elfman
Identification of the C5a des Arg cochemotaxin.
Transactions of the Association of American Physicians 1988;101():242-9.
1987: H Daniel Perez; F Elfman; Errol Lobo
Removal of human polymorphonuclear leukocyte surface sialic acid inhibits reexpression (or recycling) of formyl peptide receptors. A possible explanation for its effect on formyl peptide-induced polymorphonuclear leukocyte chemotaxis.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(6):1978-84.
1987: H Daniel Perez; F Elfman; S Marder
Meclofenamate sodium monohydrate inhibits chemotactic factor-induced human polymorphonuclear leukocyte function. A possible explanation for its antiinflammatory effect.
Arthritis and rheumatism 1987;30(9):1023-31.
1987: H Daniel Perez; C Hooper; J Volanakis; A Ueda
Specific inhibitor of complement (C5)-derived chemotactic activity in systemic lupus erythematosus related antigenically to the Bb fragment of human factor B.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(2):484-9.
1987: H Daniel Perez; S Marder; F Elfman; Harlan E Ives
Human neutrophils contain subpopulations of specific granules exhibiting different sensitivities to changes in cytosolic free calcium.
Biochemical and biophysical research communications 1987;145(2):976-81.
1986: F J Roll; D Montgomery Bissell; H Daniel Perez
Human hepatocytes metabolizing ethanol generate a non-polar chemotactic factor for human neutrophils.
Biochemical and biophysical research communications 1986;137(2):688-94.
1986: H Daniel Perez; F Elfman; D Chenoweth; C Hooper
Preparation and characterization of a derivative of wheat germ agglutinin which specifically inhibits polymorphonuclear leukocyte chemotaxis to the synthetic chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(5):1813-9.
1986: H Daniel Perez; F Elfman; Errol Lobo; L Sklar; D Chenoweth; C Hooper
A derivative of wheat germ agglutinin specifically inhibits formyl-peptide-induced polymorphonuclear leukocyte chemotaxis by blocking re-expression (or recycling) of receptors.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(5):1803-12.
1985: H Daniel Perez; R R Ong; F Elfman
Removal or oxidation of surface membrane sialic acid inhibits formyl-peptide-induced polymorphonuclear leukocyte chemotaxis.
Journal of immunology (Baltimore, Md. : 1950) 1985;134(3):1902-8.
1984: H Daniel Perez; F J Roll; D Montgomery Bissell; S Shak; I M Goldstein
Production of chemotactic activity for polymorphonuclear leukocytes by cultured rat hepatocytes exposed to ethanol.
The Journal of clinical investigation 1984;74(4):1350-7.
1983: S Shak; H Daniel Perez; I M Goldstein
A novel dioxygenation product of arachidonic acid possesses potent chemotactic activity for human polymorphonuclear leukocytes.
The Journal of biological chemistry 1983;258(24):14948-53.
1983: H Daniel Perez; D Montgomery Bissell; F J Roll; S Shak; I M Goldstein
A possible explanation for leukocytic infiltration of the liver in acute alcoholic hepatitis: ethanol-induced generation by hepatocytes of a lipid chemotactic factor.
Transactions of the Association of American Physicians 1983;96():56-64.