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Hansjürgen Agostini

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Nikolai Gross; Lutz L Hansen; Jing Hua; Gottfried Martin; Uwe Michaelis; Mahdy Ranjbar; Brita Schulze; Charlotte Evers; Hansjürgen T Agostini
Choroidal neovascularization reduced by targeted drug delivery with cationic liposome-encapsulated paclitaxel or targeted photodynamic therapy with verteporfin encapsulated in cationic liposomes.
Andreas Stahl; Michael T Stumpp; Denis Villemagne; Hansjürgen T Agostini; Savira Ekawardhani; Patrik Forrer; Maya Gulotti-Georgieva; Christina Lehrling; Gottfried Martin; Anja Schlegel; H Kaspar Binz
Highly potent VEGF-A-antagonistic DARPins as anti-angiogenic agents for topical and intravitreal applications.
Jing Hua; Gottfried Martin; Uwe Michaelis; Brita Schulze; Hermann Bohnenkamp; Nikolai Gross; Eric Guenzi; Lutz L Hansen; Hansjürgen T Agostini
In vivo imaging of choroidal angiogenesis using fluorescence-labeled cationic liposomes.

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2013: Nikolai Gross; Lutz L Hansen; Jing Hua; Gottfried Martin; Uwe Michaelis; Mahdy Ranjbar; Brita Schulze; Charlotte Evers; Hansjürgen T Agostini
Choroidal neovascularization reduced by targeted drug delivery with cationic liposome-encapsulated paclitaxel or targeted photodynamic therapy with verteporfin encapsulated in cationic liposomes.
Molecular vision 2013;19():54-61.
2013: Andreas Stahl; Michael T Stumpp; Denis Villemagne; Hansjürgen T Agostini; Savira Ekawardhani; Patrik Forrer; Maya Gulotti-Georgieva; Christina Lehrling; Gottfried Martin; Anja Schlegel; H Kaspar Binz
Highly potent VEGF-A-antagonistic DARPins as anti-angiogenic agents for topical and intravitreal applications.
Angiogenesis 2013;16(1):101-11.
2012: Jing Hua; Gottfried Martin; Uwe Michaelis; Brita Schulze; Hermann Bohnenkamp; Nikolai Gross; Eric Guenzi; Lutz L Hansen; Hansjürgen T Agostini
In vivo imaging of choroidal angiogenesis using fluorescence-labeled cationic liposomes.
Molecular vision 2012;18():1045-54.
2011: Christoph Ehlken; Nicolas Feltgen; Bastian Grundel; Lutz L Hansen; Bernd Junker; Daniel Michels; Amelie Pielen; Emma S Rennel; Andreas Stahl; Hansjürgen T Agostini; Gottfried Martin
Levels of VEGF but not VEGF(165b) are increased in the vitreous of patients with retinal vein occlusion.
American journal of ophthalmology 2011;152(2):298-303.e1.
2011: Christine Schmucker; Yoon K Loke; Christoph Ehlken; Hansjürgen T Agostini; Lutz L Hansen; Gerd Antes; Monika Lelgemann
Intravitreal bevacizumab (Avastin) versus ranibizumab (Lucentis) for the treatment of age-related macular degeneration: a safety review.
The British journal of ophthalmology 2011;95(3):308-17.
2011: Christoph Ehlken; Gottfried Martin; Clemens Lange; Eleni G Gogaki; Ulrike Fiedler; Florence Schaffner; Lutz L Hansen; Hellmut G Augustin; Hansjürgen T Agostini
Therapeutic interference with EphrinB2 signalling inhibits oxygen-induced angioproliferative retinopathy.
Acta ophthalmologica 2011;89(1):82-90.
2011: Franziska Fischer; Gottfried Martin; Hansjürgen T Agostini
Activation of retinal microglia rather than microglial cell density correlates with retinal neovascularization in the mouse model of oxygen-induced retinopathy.
Journal of neuroinflammation 2011;8():120.
2010: Anette L Magnussen; Emma S Rennel; Jing Hua; Heather S Bevan; Nicholas Beazley Long; Christina Lehrling; Melissa Gammons; Juergen Floege; Steven J Harper; Hansjürgen T Agostini; David O Bates; Amanda J Churchill
VEGF-A165b is cytoprotective and antiangiogenic in the retina.
Investigative ophthalmology & visual science 2010;51(8):4273-81.
2010: Christina Pieh; Marcus Krüger; Wolf Alexander Lagrèze; Charlotte Gimpel; Christiane Buschbeck; Ute Zirrgiebel; Hansjürgen T Agostini
Plasma sE-selectin in premature infants: a possible surrogate marker of retinopathy of prematurity.
Investigative ophthalmology & visual science 2010;51(7):3709-13.
2010: Andreas Stahl; Isabell Struebin; Lutz L Hansen; Hansjürgen T Agostini; Nicolas Feltgen
Bevacizumab in central retinal vein occlusion: a retrospective analysis after 2 years of treatment.
European journal of ophthalmology 2010;20(1):180-5.
2009: Andreas Stahl; Lilija Paschek; Gottfried Martin; Nicolas Feltgen; Lutz L Hansen; Hansjürgen T Agostini
Combinatory inhibition of VEGF and FGF2 is superior to solitary VEGF inhibition in an in vitro model of RPE-induced angiogenesis.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2009;247(6):767-73.
2009: Nicolas Feltgen; Hansjürgen T Agostini; Claudia Auw-Haedrich; Lutz L Hansen
Histopathological findings after retinal endovascular lysis in central retinal vein occlusion.
BMJ case reports 2009;2009():.
2008: C Pieh; Hansjürgen T Agostini; C Buschbeck; M Krüger; J Schulte-Mönting; U Zirrgiebel; J Drevs; Wolf A Lagrèze
VEGF-A, VEGFR-1, VEGFR-2 and Tie2 levels in plasma of premature infants: relationship to retinopathy of prematurity.
The British journal of ophthalmology 2008;92(5):689-93.
2008: Hansjürgen T Agostini; Nicolas Feltgen; L Hansen
[Anti-angiogenic therapy in ocular disease--current and future strategies].
Klinische Monatsblätter für Augenheilkunde 2008;225(1):39-43.
2007: Andreas Stahl; Hansjürgen T Agostini; Lutz L Hansen; Nicolas Feltgen
Bevacizumab in retinal vein occlusion-results of a prospective case series.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2007;245(10):1429-36.
2007: Clemens Lange; Christoph Ehlken; Gottfried Martin; Kirstin Konzok; Jaime Moscoso Del Prado; Lutz L Hansen; Hansjürgen T Agostini
Intravitreal injection of the heparin analog 5-amino-2-naphthalenesulfonate reduces retinal neovascularization in mice.
Experimental eye research 2007;85(3):323-7.
2007: Hansjürgen T Agostini; Lutz L Hansen; Nicolas Feltgen
[Treatment of pseudophakic cystoid macular edema].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2007;104(5):425-6, 428-30.
2007: Nicolas Feltgen; Hansjürgen T Agostini; L Hansen
[Surgical treatments for retinal vein occlusion].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2007;104(4):279-84.
2007: Nicolas Feltgen; Hansjürgen T Agostini; Claudia Auw-Haedrich; Lutz L Hansen
Histopathological findings after retinal endovascular lysis in central retinal vein occlusion.
The British journal of ophthalmology 2007;91(4):558-9.
2007: Nicolas Feltgen; Bernd Junker; Hansjürgen T Agostini; Lutz L Hansen
Retinal endovascular lysis in ischemic central retinal vein occlusion: one-year results of a pilot study.
Ophthalmology 2007;114(4):716-23.
2007: Bernd Junker; D Schmidt; Hansjürgen T Agostini
[Retinal angiomatosis. Ocular manifestation of von Hippel-Lindau disease].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2007;104(2):107-13.
2007: Rita Rosenthal; Heinrich Heimann; Hansjürgen T Agostini; Gottfried Martin; Lutz L Hansen; Olaf Strauss
Ca2+ channels in retinal pigment epithelial cells regulate vascular endothelial growth factor secretion rates in health and disease.
Molecular vision 2007;13():443-56.
2006: Thomas Kube; M Sutter; Rainer Trittler; Nicolas Feltgen; Lutz L Hansen; Hansjürgen T Agostini
Carboxymethylcellulose as a new carrier substance for intravitreal injection of reproducible amounts of triamcinolone.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2006;244(11):1385-90.
2006: Nicolas Feltgen; Julia Herrmann; Hansjürgen T Agostini; Adel Sammain; Lutz L Hansen
Arterio-venous dissection after isovolaemic haemodilution in branch retinal vein occlusion: a non-randomised prospective study.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2006;244(7):829-35.
2005: Philip Maier; Anke S Unsoeld; Bernd Junker; Gottfried Martin; Joachim Drevs; Lutz L Hansen; Hansjürgen T Agostini
Intravitreal injection of specific receptor tyrosine kinase inhibitor PTK787/ZK222 584 improves ischemia-induced retinopathy in mice.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2005;243(6):593-600.
2005: Hansjürgen T Agostini; Karl Boden; Anke Unsöld; Gottfried Martin; Lutz Hansen; Ulrike Fiedler; Norbert Esser; Dieter Marmé
A single local injection of recombinant VEGF receptor 2 but not of Tie2 inhibits retinal neovascularization in the mouse.
Current eye research 2005;30(4):249-57.
2005: Philipp Eberwein; Lutz L Hansen; Hansjürgen T Agostini
Genotypes of JC virus, DNA of cytomegalovirus, and proviral DNA of human immunodeficiency virus in eyes of acquired immunodeficiency syndrome patients.
Journal of neurovirology 2005;11(1):58-65.
2005: Gottfried Martin; Hansjürgen T Agostini; Lutz L Hansen
Light emitting diode microscope illumination for green fluorescent protein or fluorescein isothiocyanate epifluorescence.
BioTechniques 2005;38(2):204, 206.
2004: Anke S Unsoeld; Bernd Junker; Ralph Mazitschek; Gottfried Martin; Lutz L Hansen; Athanassios Giannis; Hansjürgen T Agostini
Local injection of receptor tyrosine kinase inhibitor MAE 87 reduces retinal neovascularization in mice.
Molecular vision 2004;10():468-75.
2004: Xiaohong Cui; Jian C Wang; Alison Deckhut; Bindu C Joseph; Philipp Eberwein; Christopher L Cubitt; Caroline Ryschkewitsch; Hansjürgen T Agostini; Gerald L Stoner
Chinese strains (Type 7) of JC virus are afro-asiatic in origin but are phylogenetically distinct from the Mongolian and Indian strains (Type 2D) and the Korean and Japanese strains (Type 2A).
Journal of molecular evolution 2004;58(5):568-83.
2004: Philip Maier; L L Hansen; Hansjürgen T Agostini
Severe retinal damage after macular hole surgery with extensive indocyanine green-assisted internal limiting membrane peeling.
Eye (London, England) 2004;18(5):538-9.
2004: Gottfried Martin; Günther Schlunck; Lutz L Hansen; Hansjürgen T Agostini
Differential expression of angioregulatory factors in normal and CNV-derived human retinal pigment epithelium.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2004;242(4):321-6.
2003: Hansjürgen T Agostini; Lutz L Hansen
[Angioproliferative retinal disease caused by ischemia].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 2003;100(5):371-7.
2002: Richard Yanagihara; Vivek R Nerurkar; Iris Scheirich; Hansjürgen T Agostini; Charles S Mgone; Xiaohong Cui; David V Jobes; Christopher L Cubitt; Caroline Ryschkewitsch; Daniel B Hrdy; Jonathan Friedlaender; Gerald L Stoner
JC virus genotypes in the western Pacific suggest Asian mainland relationships and virus association with early population movements.
Human biology 2002;74(3):473-88.
2002: Mariana Fernandez-Cobo; Hansjürgen T Agostini; Graciela Britez; Caroline Ryschkewitsch; Gerald L Stoner
Strains of JC virus in Amerind-speakers of North America (Salish) and South America (Guaraní), Na-Dene-speakers of New Mexico (Navajo), and modern Japanese suggest links through an ancestral Asian population.
American journal of physical anthropology 2002;118(2):154-68.
2002: Günther Schlunck; Gottfried Martin; Hansjürgen T Agostini; Gabriele Camatta; Lutz L Hansen
Cultivation of retinal pigment epithelial cells from human choroidal neovascular membranes in age related macular degeneration.
Experimental eye research 2002;74(5):571-6.
2001: Christopher L Cubitt; Xiaohong Cui; Hansjürgen T Agostini; Vivek R Nerurkar; I Scheirich; Richard Yanagihara; Caroline Ryschkewitsch; Gerald L Stoner
Predicted amino acid sequences for 100 JCV strains.
Journal of neurovirology 2001;7(4):339-44.
2001: Hansjürgen T Agostini; A Deckhut; David V Jobes; Rosina Girones; Günther Schlunck; M G Prost; C Frias; E Pérez-Trallero; Caroline Ryschkewitsch; Gerald L Stoner
Genotypes of JC virus in East, Central and Southwest Europe.
The Journal of general virology 2001;82(Pt 5):1221-331.
2001: D V Jobe; Jonathan Friedlaender; Charles S Mgone; Hansjürgen T Agostini; George Koki; Richard Yanagihara; SC Chima; Caroline Ryschkewitsch; Gerald L Stoner
New JC virus (JCV) genotypes from papua new guinea and micronesia (type 8 and type 2E) and evolutionary analysis of 32 complete JCV genomes.
Archives of virology 2001;146(11):2097-113.
2000: Gerald L Stoner; David V Jobes; Mariana Fernandez-Cobo; Hansjürgen T Agostini; SC Chima; Caroline Ryschkewitsch
JC virus as a marker of human migration to the Americas.
Microbes and infection / Institut Pasteur 2000;2(15):1905-11.
2000: Caroline Ryschkewitsch; Jonathan Friedlaender; Charles S Mgone; David V Jobes; Hansjürgen T Agostini; SC Chima; MP Alpers; George Koki; Richard Yanagihara; Gerald L Stoner
Human polyomavirus JC variants in Papua New Guinea and Guam reflect ancient population settlement and viral evolution.
Microbes and infection / Institut Pasteur 2000;2(9):987-96.
2000: Hansjürgen T Agostini; Caroline Ryschkewitsch; RW Baumhefner; W W Tourtellotte; EJ Singer; Sámuel Komoly; Gerald L Stoner
Influence of JC virus coding region genotype on risk of multiple sclerosis and progressive multifocal leukoencephalopathy.
Journal of neurovirology 2000;6 Suppl 2():S101-8.
1999: SC Chima; Hansjürgen T Agostini; Caroline Ryschkewitsch; Sebastian Lucas; Gerald L Stoner
Progressive multifocal leukoencephalopathy and JC virus genotypes in West African patients with acquired immunodeficiency syndrome: a pathologic and DNA sequence analysis of 4 cases.
Archives of pathology & laboratory medicine 1999;123(5):395-403.
1998: Gerald L Stoner; Hansjürgen T Agostini; Caroline Ryschkewitsch; M Mazló; F Gullotta; W Wamukota; Sebastian Lucas
Detection of JC virus in two African cases of progressive multifocal leukoencephalopathy including identification of JCV type 3 in a Gambian AIDS patient.
Journal of medical microbiology 1998;47(8):733-42.
1998: Hansjürgen T Agostini; Caroline Ryschkewitsch; Gerald L Stoner
Complete genome of a JC virus genotype type 6 from the brain of an African American with progressive multifocal leukoencephalopathy.
Journal of human virology 1998;1(4):267-72.
1998: Hansjürgen T Agostini; Caroline Ryschkewitsch; Gerald L Stoner
Rearrangements of archetypal regulatory regions in JC virus genomes from urine.
Research in virology 1998;149(3):163-70.
1998: Hansjürgen T Agostini; Y Shishido-Hara; RW Baumhefner; EJ Singer; Caroline Ryschkewitsch; Gerald L Stoner
JC virusType 2: definition of subtypes based on DNA sequence analysis of ten complete genomes.
The Journal of general virology 1998;79 ( Pt 5)():1143-51.
1998: Gerald L Stoner; Hansjürgen T Agostini; Caroline Ryschkewitsch; Sámuel Komoly
JC virus excreted by multiple sclerosis patients and paired controls from Hungary.
Multiple sclerosis (Houndmills, Basingstoke, England) 1998;4(2):45-8.
1998: Hansjürgen T Agostini; Caroline Ryschkewitsch; Gerald L Stoner
JC virus Type 1 has multiple subtypes: three new complete genomes.
The Journal of general virology 1998;79 ( Pt 4)():801-5.
1998: Hansjürgen T Agostini; Caroline Ryschkewitsch; EJ Singer; RW Baumhefner; Gerald L Stoner
JC virus type 2B is found more frequently in brain tissue of progressive multifocal leukoencephalopathy patients than in urine from controls.
Journal of human virology 1998;1(3):200-6.
1997: Hansjürgen T Agostini; Richard Yanagihara; V Davis; Caroline Ryschkewitsch; Gerald L Stoner
Asian genotypes of JC virus in Native Americans and in a Pacific Island population: markers of viral evolution and human migration.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14542-6.
1997: Hansjürgen T Agostini; Caroline Ryschkewitsch; R Mory; EJ Singer; Gerald L Stoner
JC virus (JCV) genotypes in brain tissue from patients with progressive multifocal leukoencephalopathy (PML) and in urine from controls without PML: increased frequency of JCV type 2 in PML.
The Journal of infectious diseases 1997;176(1):1-8.
1997: Hansjürgen T Agostini; Caroline Ryschkewitsch; EJ Singer; Gerald L Stoner
JC virus regulatory region rearrangements and genotypes in progressive multifocal leukoencephalopathy: two independent aspects of virus variation.
The Journal of general virology 1997;78 ( Pt 3)():659-64.
1997: Hansjürgen T Agostini; Caroline Ryschkewitsch; G R Brubaker; J Shao; G I Stoner
Five complete genomes of JC virus type 3 from Africans and African Americans.
Archives of virology 1997;142(4):637-55.
1996: Hansjürgen T Agostini; Caroline Ryschkewitsch; EJ Singer; Gerald L Stoner
Co-infection with two JC virus genotypes in brain, cerebrospinal fluid or urinary tract detected by direct cycle sequencing of PCR products.
Journal of neurovirology 1996;2(4):259-67.
1996: Gerald L Stoner; Hansjürgen T Agostini; Caroline Ryschkewitsch; R W Baumhefner; W W Tourtellotte
Characterization of JC virus DNA amplified from urine of chronic progressive multiple sclerosis patients.
Multiple sclerosis (Houndmills, Basingstoke, England) 1996;1(4):193-9.
1996: Hansjürgen T Agostini; Caroline Ryschkewitsch; Gerald L Stoner
Genotype profile of human polyomavirus JC excreted in urine of immunocompetent individuals.
Journal of clinical microbiology 1996;34(1):159-64.
1995: Hansjürgen T Agostini; Gerald L Stoner
Amplification of the complete polyomavirus JC genome from brain, cerebrospinal fluid and urine using pre-PCR restriction enzyme digestion.
Journal of neurovirology 1995;1(3-4):316-20.
1995: Hansjürgen T Agostini; G R Brubaker; J Shao; A Levin; Caroline Ryschkewitsch; William A Blattner; Gerald L Stoner
BK virus and a new type of JC virus excreted by HIV-1 positive patients in rural Tanzania.
Archives of virology 1995;140(11):1919-34.