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Daniel Perl

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Michal Schnaider Beeri; Gerson T Lesser; Stephanie Leung; Maria Maroukian; Daniel P Perl; Dushyant P Purohit; James Schmeidler; Rebecca West; Michael Wysocki; Vahram Haroutunian
Corticosteroids, but not NSAIDs, are associated with less Alzheimer neuropathology.
Dushyant P Purohit; Nirmala O Batheja; Mary Sano; Kusum D Jashnani; Rajesh N Kalaria; Arivarasan Karunamurthy; Shalinder Kaur; Asha S Shenoy; Kathleen Van Dyk; James Schmeidler; Daniel P Perl
Profiles of Alzheimer's disease-related pathology in an aging urban population sample in India.
Ann C McKee; Brandon E Gavett; Robert A Stern; Christopher J Nowinski; Robert C Cantu; Neil W Kowall; Daniel P Perl; E Tessa Hedley-Whyte; Bruce Price; Chris Sullivan; Peter Morin; Hyo-Soon Lee; Caroline A Kubilus; Daniel H Daneshvar; Megan Wulff; Andrew E Budson
TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy.

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2012: Michal Schnaider Beeri; Gerson T Lesser; Stephanie Leung; Maria Maroukian; Daniel P Perl; Dushyant P Purohit; James Schmeidler; Rebecca West; Michael Wysocki; Vahram Haroutunian
Corticosteroids, but not NSAIDs, are associated with less Alzheimer neuropathology.
Neurobiology of aging 2012;33(7):1258-64.
2011: Dushyant P Purohit; Nirmala O Batheja; Mary Sano; Kusum D Jashnani; Rajesh N Kalaria; Arivarasan Karunamurthy; Shalinder Kaur; Asha S Shenoy; Kathleen Van Dyk; James Schmeidler; Daniel P Perl
Profiles of Alzheimer's disease-related pathology in an aging urban population sample in India.
Journal of Alzheimer's disease : JAD 2011;24(1):187-96.
2010: Ann C McKee; Brandon E Gavett; Robert A Stern; Christopher J Nowinski; Robert C Cantu; Neil W Kowall; Daniel P Perl; E Tessa Hedley-Whyte; Bruce Price; Chris Sullivan; Peter Morin; Hyo-Soon Lee; Caroline A Kubilus; Daniel H Daneshvar; Megan Wulff; Andrew E Budson
TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy.
Journal of neuropathology and experimental neurology 2010;69(9):918-29.
2010: Daniel P Perl
Neuropathology of Alzheimer's disease.
The Mount Sinai journal of medicine, New York 2010;77(1):32-42.
2009: Michal Schnaider Beeri; Michael A Rapp; James Schmeidler; Abraham Reichenberg; Dushyant P Purohit; Daniel P Perl; Hillel T Grossman; Isak Prohovnik; Vahram Haroutunian; Jeremy Silverman
Number of children is associated with neuropathology of Alzheimer's disease in women.
Neurobiology of aging 2009;30(8):1184-91.
2008: Rajiv M Agashiwala; Elan D Louis; Patrick R Hof; Daniel P Perl
A novel approach to non-biased systematic random sampling: a stereologic estimate of Purkinje cells in the human cerebellum.
Brain research 2008;1236():73-8.
2008: Vahram Haroutunian; Michal Schnaider Beeri; James Schmeidler; Michael Wysocki; Dushyant P Purohit; Daniel P Perl; Leslie S Libow; Gerson T Lesser; Maria Maroukian; Hillel T Grossman
Role of the neuropathology of Alzheimer disease in dementia in the oldest-old.
Archives of neurology 2008;65(9):1211-7.
2008: Afia Akram; Daniel Christoffel; Anne B Rocher; Constantin Bouras; Enikö Kövari; Daniel P Perl; John H Morrison; Francois Herrmann; Vahram Haroutunian; Panteleimon Giannakopoulos; Patrick R Hof
Stereologic estimates of total spinophilin-immunoreactive spine number in area 9 and the CA1 field: relationship with the progression of Alzheimer's disease.
Neurobiology of aging 2008;29(9):1296-307.
2008: Michael A Rapp; Michal Schnaider Beeri; Dushyant P Purohit; Daniel P Perl; Vahram Haroutunian; Mary Sano
Increased neurofibrillary tangles in patients with Alzheimer disease with comorbid depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2008;16(2):168-74.
2008: Michal Schnaider Beeri; Jeremy Silverman; James Schmeidler; Michael Wysocki; Hillel Z Grossman; Dushyant P Purohit; Daniel P Perl; Vahram Haroutunian
Clinical dementia rating performed several years prior to death predicts regional Alzheimer's neuropathology.
Dementia and geriatric cognitive disorders 2008;25(5):392-8.
2008: Felix Geser; Matthew J Winton; Linda K Kwong; Yan Xu; Sharon X Xie; Lionel M Igaz; Ralph M Garruto; Daniel P Perl; Douglas Galasko; Virginia M-Y Lee; John Q Trojanowski
Pathological TDP-43 in parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam.
Acta neuropathologica 2008;115(1):133-45.
2007: Wan Yang; Randall L Woltjer; Izabela Sokal; Catherine Pan; Yan Wang; Mary Brodey; Elaine Peskind; James B Leverenz; Jing Zhang; Daniel P Perl; Douglas Galasko; Thomas J Montine
Quantitative proteomics identifies surfactant-resistant alpha-synuclein in cerebral cortex of Parkinsonism-dementia complex of Guam but not Alzheimer's disease or progressive supranuclear palsy.
The American journal of pathology 2007;171(3):993-1002.
2007: Daniel P Perl; C Warren Olanow
The neuropathology of manganese-induced Parkinsonism.
Journal of neuropathology and experimental neurology 2007;66(8):675-82.
2007: Daniel P Perl
The role of the pathologist in translational and personalized medicine.
The Mount Sinai journal of medicine, New York 2007;74(1):22-6.
2007: Daniel P Perl
The neuropathology of parkinsonism.
Handbook of clinical neurology 2007;83():205-15.
2006: Daniel P Perl
Exposure to aluminium and the subsequent development of a disorder with features of Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2006;77(7):811.
2006: Michal Schnaider Beeri; Michael A Rapp; Jeremy Silverman; James Schmeidler; Hillel T Grossman; J T Fallon; Dushyant P Purohit; Daniel P Perl; A Siddiqui; G Lesser; Clive Rosendorff; Vahram Haroutunian
Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers.
Neurology 2006;66(9):1399-404.
2006: Matthew J Winton; Sonali Joyce; Victoria Zhukareva; Domenico Practico; Daniel P Perl; Douglas Galasko; Ulla-Katrina Craig; John Q Trojanowski; Virginia M-Y Lee
Characterization of tau pathologies in gray and white matter of Guam parkinsonism-dementia complex.
Acta neuropathologica 2006;111(5):401-12.
2006: Michael A Rapp; Michal Schnaider Beeri; Hillel T Grossman; Mary Sano; Daniel P Perl; Dushyant P Purohit; Jack M Gorman; Vahram Haroutunian
Increased hippocampal plaques and tangles in patients with Alzheimer disease with a lifetime history of major depression.
Archives of general psychiatry 2006;63(2):161-7.
2006: Isak Prohovnik; Daniel P Perl; Kenneth L Davis; Leslie S Libow; G Lesser; Vahram Haroutunian
Dissociation of neuropathology from severity of dementia in late-onset Alzheimer disease.
Neurology 2006;66(1):49-55.
2006: Daniel P Perl; Sharon Moalem
Aluminum and Alzheimer's disease, a personal perspective after 25 years.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):291-300.
2005: Thomas J Montine; Ke Li; Daniel P Perl; Douglas Galasko
Lack of beta-methylamino-l-alanine in brain from controls, AD, or Chamorros with PDC.
Neurology 2005;65(5):768-9.
2005: Michal Schnaider Beeri; Jeremy Silverman; Kenneth L Davis; Deborah B Marin; Hillel Z Grossman; James Schmeidler; Dushyant P Purohit; Daniel P Perl; Michael Davidson; Richard C Mohs; Vahram Haroutunian
Type 2 diabetes is negatively associated with Alzheimer's disease neuropathology.
The journals of gerontology. Series A, Biological sciences and medical sciences 2005;60(4):471-5.
2004: Daniel P Perl; Ursula Fogarty; Noam Harpaz; David B Sachar
Bacterial-metal interactions: the potential role of aluminum and other trace elements in the etiology of Crohn's disease.
Inflammatory bowel diseases 2004;10(6):881-3.
2004: Paul F Good; Daisy V Alapat; Amy Hsu; Caryn Chu; Daniel P Perl; Xiaping Wen; David E Burstein; D Stave Kohtz
A role for semaphorin 3A signaling in the degeneration of hippocampal neurons during Alzheimer's disease.
Journal of neurochemistry 2004;91(3):716-36.
2004: Kevin St P McNaught; Alexander Kapustin; Tehone Jackson; Toni-Ann Jengelley; Ruth Jnobaptiste; Pullanipally Shashidharan; Daniel P Perl; Pedro Pasik; C Warren Olanow
Brainstem pathology in DYT1 primary torsion dystonia.
Annals of neurology 2004;56(4):540-7.
2004: C Warren Olanow; Daniel P Perl; George N DeMartino; Kevin St P McNaught
Lewy-body formation is an aggresome-related process: a hypothesis.
Lancet neurology 2004;3(8):496-503.
2004: Kevin St P McNaught; Daniel P Perl; Anna-Liisa Brownell; C Warren Olanow
Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease.
Annals of neurology 2004;56(1):149-62.
2004: Joseph Sebeo; Patrick R Hof; Daniel P Perl
Occurrence of alpha-synuclein pathology in the cerebellum of Guamanian patients with parkinsonism-dementia complex.
Acta neuropathologica 2004;107(6):497-503.
2003: C Warren Olanow; Christopher G Goetz; Jeffrey Kordower; A Jon Stoessl; Vesna Sossi; Mitchell F Brin; Kathleen M Shannon; G Michael Nauert; Daniel P Perl; James Godbold; Thomas B Freeman
A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease.
Annals of neurology 2003;54(3):403-14.
2003: Thierry Bussière; Panteleimon Giannakopoulos; Constantin Bouras; Daniel P Perl; John H Morrison; Patrick R Hof
Progressive degeneration of nonphosphorylated neurofilament protein-enriched pyramidal neurons predicts cognitive impairment in Alzheimer's disease: stereologic analysis of prefrontal cortex area 9.
The Journal of comparative neurology 2003;463(3):281-302.
2003: Patrick R Hof; Vahram Haroutunian; Victor L Friedrich; William Byne; Cristian Buitron; Daniel P Perl; Kenneth L Davis
Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia.
Biological psychiatry 2003;53(12):1075-85.
2003: Panteleimon Giannakopoulos; Francois Herrmann; Thierry Bussière; Constantin Bouras; Enikö Kövari; Daniel P Perl; John H Morrison; Gabriel Gold; Patrick R Hof
Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease.
Neurology 2003;60(9):1495-500.
2003: Daniel P Perl; Patrick R Hof; Dushyant P Purohit; Arthur J Loerzel; Byron A Kakulas
Hippocampal and entorhinal cortex neurofibrillary tangle formation in Guamanian Chamorros free of overt neurologic dysfunction.
Journal of neuropathology and experimental neurology 2003;62(4):381-8.
2003: Thierry Bussière; Gabriel Gold; Enikö Kövari; Panteleimon Giannakopoulos; Constantin Bouras; Daniel P Perl; John H Morrison; Patrick R Hof
Stereologic analysis of neurofibrillary tangle formation in prefrontal cortex area 9 in aging and Alzheimer's disease.
Neuroscience 2003;117(3):577-92.
2003: Patrick R Hof; Thierry Bussière; Gabriel Gold; Enikö Kövari; Panteleimon Giannakopoulos; Constantin Bouras; Daniel P Perl; John H Morrison
Stereologic evidence for persistence of viable neurons in layer II of the entorhinal cortex and the CA1 field in Alzheimer disease.
Journal of neuropathology and experimental neurology 2003;62(1):55-67.
2002: Kevin St P McNaught; Pullanipally Shashidharan; Daniel P Perl; Peter Jenner; C Warren Olanow
Aggresome-related biogenesis of Lewy bodies.
The European journal of neuroscience 2002;16(11):2136-48.
2002: Patrick R Hof; Daniel P Perl
Neurofibrillary tangles in the primary motor cortex in Guamanian amyotrophic lateral sclerosis/parkinsonism-dementia complex.
Neuroscience letters 2002;328(3):294-8.
2002: Ruth H Walker; Dushyant P Purohit; Paul F Good; Daniel P Perl; Mitchell F Brin
Severe generalized dystonia due to primary putaminal degeneration: case report and review of the literature.
Movement disorders : official journal of the Movement Disorder Society 2002;17(3):576-84.
2002: Mark S Forman; M Luise Schmidt; Sanjay Kasturi; Daniel P Perl; Virginia M-Y Lee; John Q Trojanowski
Tau and alpha-synuclein pathology in amygdala of Parkinsonism-dementia complex patients of Guam.
The American journal of pathology 2002;160(5):1725-31.
2002: Martin M Evers; Dushyant P Purohit; Daniel P Perl; Khalid Khan; Deborah B Marin
Palliative and aggressive end-of-life care for patients with dementia.
Psychiatric services (Washington, D.C.) 2002;53(5):609-13.
2002: Thierry Bussière; P D Friend; N Sadeghi; B Wicinski; G I Lin; Constantin Bouras; Panteleimon Giannakopoulos; Nikolaos K Robakis; John H Morrison; Daniel P Perl; Patrick R Hof
Stereologic assessment of the total cortical volume occupied by amyloid deposits and its relationship with cognitive status in aging and Alzheimer's disease.
Neuroscience 2002;112(1):75-91.
2001: Eliezer Masliah; Michael Alford; Douglas Galasko; David P Salmon; Lawrence A Hansen; Paul F Good; Daniel P Perl; Leon J Thal
Cholinergic deficits in the brains of patients with parkinsonism-dementia complex of Guam.
Neuroreport 2001;12(18):3901-3.
2001: Parvoneh Poorkaj-Navas; Debby W Tsuang; Ellen M Wijsman; Ellen J Steinbart; Ralph M Garruto; Ulla-Katrina Craig; N H Chapman; L Anderson; Thomas D Bird; Chris C Plato; Daniel P Perl; W Weiderholt; Douglas Galasko; Gerard D Schellenberg
TAU as a susceptibility gene for amyotropic lateral sclerosis-parkinsonism dementia complex of Guam.
Archives of neurology 2001;58(11):1871-8.
2001: M Luise Schmidt; Victoria Zhukareva; Daniel P Perl; S K Sheridan; Teresa Schuck; Virginia M-Y Lee; John Q Trojanowski
Spinal cord neurofibrillary pathology in Alzheimer disease and Guam Parkinsonism-dementia complex.
Journal of neuropathology and experimental neurology 2001;60(11):1075-86.
2001: Brent A Vogt; Leslie J Vogt; Daniel P Perl; Patrick R Hof
Cytology of human caudomedial cingulate, retrosplenial, and caudal parahippocampal cortices.
The Journal of comparative neurology 2001;438(3):353-76.
2001: Patrick R Hof; EA Nimchinsky; Daniel P Perl; Joseph M Erwin
An unusual population of pyramidal neurons in the anterior cingulate cortex of hominids contains the calcium-binding protein calretinin.
Neuroscience letters 2001;307(3):139-42.
2001: C Schmitz; H Korr; Daniel P Perl; Patrick R Hof
Advanced use of 3-D methods for counting neurons.
Trends in neurosciences 2001;24(7):377-80.
2001: Horacio Kaufmann; Karin Hague; Daniel P Perl
Accumulation of alpha-synuclein in autonomic nerves in pure autonomic failure.
Neurology 2001;56(7):980-1.
2001: Daniel P Perl
Barney Sachs and the history of the neuropathologic description of Tay-Sachs disease.
Advances in genetics 2001;44():11-23.
2000: Daniel P Perl
Neuropathology of Alzheimer's disease and related disorders.
Neurologic clinics 2000;18(4):847-64.
2000: Daniel P Perl; Paul F Good; Thierry Bussière; John H Morrison; Joseph M Erwin; Patrick R Hof
Practical approaches to stereology in the setting of aging- and disease-related brain banks.
Journal of chemical neuroanatomy 2000;20(1):7-19.
2000: Pullanipally Shashidharan; Paul F Good; Amy Hsu; Daniel P Perl; Mitchell F Brin; C Warren Olanow
TorsinA accumulation in Lewy bodies in sporadic Parkinson's disease.
Brain research 2000;877(2):379-81.
2000: Vahram Haroutunian; Michael Serby; Dushyant P Purohit; Daniel P Perl; Deborah B Marin; Melinda Lantz; Richard C Mohs; Kenneth L Davis
Contribution of Lewy body inclusions to dementia in patients with and without Alzheimer disease neuropathological conditions.
Archives of neurology 2000;57(8):1145-50.
2000: Michele Tagliati; Daniel P Perl; B Drayer; C Warren Olanow
Progressive dementia and gait disorder in a 78 year old woman.
Journal of neurology, neurosurgery, and psychiatry 2000;68(4):526-31.
2000: Joseph Jankovic; Ali H Rajput; M P McDermott; Daniel P Perl
The evolution of diagnosis in early Parkinson disease. Parkinson Study Group.
Archives of neurology 2000;57(3):369-72.
2000: Kiyomitsu Oyanagi; Kwang-Ming Chen; Ulla-Katrina Craig; Mineo Yamazaki; Daniel P Perl
Parkinsonism, dementia and vertical gaze palsy in a Guamanian with atypical neuroglial degeneration.
Acta neuropathologica 2000;99(1):73-80.
1999: Kenneth L Davis; Richard C Mohs; Deborah B Marin; Dushyant P Purohit; Daniel P Perl; Melinda Lantz; G Austin; Vahram Haroutunian
Neuropeptide abnormalities in patients with early Alzheimer disease.
Archives of general psychiatry 1999;56(11):981-7.
1999: Vahram Haroutunian; Dushyant P Purohit; Daniel P Perl; Deborah B Marin; K Khan; Melinda Lantz; Kenneth L Davis; Richard C Mohs
Neurofibrillary tangles in nondemented elderly subjects and mild Alzheimer disease.
Archives of neurology 1999;56(6):713-8.
1999: S Tang; Patrick J Parsons; Daniel P Perl
Longitudinal and lateral variations in the aluminum concentration of selected caprine, bovine, and human bone samples.
Biological trace element research 1999;68(3):267-79.
1999: EA Nimchinsky; Emmanuel P E Gilissen; John M Allman; Daniel P Perl; Joseph M Erwin; Patrick R Hof
A neuronal morphologic type unique to humans and great apes.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5268-73.
1999: Kenneth L Davis; Richard C Mohs; Deborah B Marin; Dushyant P Purohit; Daniel P Perl; Melinda Lantz; G Austin; Vahram Haroutunian
Cholinergic markers in elderly patients with early signs of Alzheimer disease.
JAMA : the journal of the American Medical Association 1999;281(15):1401-6.
1999: Thierry Bussière; Patrick R Hof; Christel Mailliot; C D Brown; Marie-Laure Caillet-Boudin; Daniel P Perl; Luc BUEE; André Delacourte
Phosphorylated serine422 on tau proteins is a pathological epitope found in several diseases with neurofibrillary degeneration.
Acta neuropathologica 1999;97(3):221-30.
1998: U Fogarty; Daniel P Perl; P Good; S Ensley; A Seawright; J Noonan
A cluster of equine granulomatous enteritis cases: the link with aluminium.
Veterinary and human toxicology 1998;40(5):297-305.
1998: Nadine A Tatton; A Maclean-Fraser; William G Tatton; Daniel P Perl; C Warren Olanow
A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease.
Annals of neurology 1998;44(3 Suppl 1):S142-8.
1998: Daniel P Perl; C Warren Olanow; Donald B Calne
Alzheimer's disease and Parkinson's disease: distinct entities or extremes of a spectrum of neurodegeneration?
Annals of neurology 1998;44(3 Suppl 1):S19-31.
1998: Vahram Haroutunian; Daniel P Perl; Dushyant P Purohit; Deborah B Marin; K Khan; Melinda Lantz; Kenneth L Davis; Richard C Mohs
Regional distribution of neuritic plaques in the nondemented elderly and subjects with very mild Alzheimer disease.
Archives of neurology 1998;55(9):1185-91.
1998: Paul F Good; Amy Hsu; P Werner; Daniel P Perl; C Warren Olanow
Protein nitration in Parkinson's disease.
Journal of neuropathology and experimental neurology 1998;57(4):338-42.
1998: Dushyant P Purohit; Daniel P Perl; Vahram Haroutunian; Peter Powchik; Michael Davidson; Kenneth L Davis
Alzheimer disease and related neurodegenerative diseases in elderly patients with schizophrenia: a postmortem neuropathologic study of 100 cases.
Archives of general psychiatry 1998;55(3):205-11.
1998: M Luise Schmidt; Virginia M-Y Lee; Takaomi C Saido; Daniel P Perl; Teresa Schuck; Takeshi Iwatsubo; John Q Trojanowski
Amyloid plaques in Guam amyotrophic lateral sclerosis/parkinsonism-dementia complex contain species of A beta similar to those found in the amyloid plaques of Alzheimer's disease and pathological aging.
Acta neuropathologica 1998;95(2):117-22.
1998: Peter Powchik; Michael Davidson; Vahram Haroutunian; SM Gabriel; Dushyant P Purohit; Daniel P Perl; Philip D Harvey; Kenneth L Davis
Postmortem studies in schizophrenia.
Schizophrenia bulletin 1998;24(3):325-41.
1997: V Buée-Scherrer; Luc BUEE; B Leveugle; Daniel P Perl; P Vermersch; Patrick R Hof; André Delacourte
Pathological tau proteins in postencephalitic parkinsonism: comparison with Alzheimer's disease and other neurodegenerative disorders.
Annals of neurology 1997;42(3):356-9.
1997: Peter Powchik; J Friedman; Vahram Haroutunian; D Greenberg; L Altsteil; Dushyant P Purohit; Daniel P Perl; Michael Davidson
Apolipoprotein E4 in schizophrenia: a study of one hundred sixteen cases with concomitant neuropathological examination.
Biological psychiatry 1997;42(4):296-8.
1997: Daniel P Perl; Dushyant P Purohit
Proposal to revise the morphologic criteria for the diagnosis of Alzheimer's disease.
Neurobiology of aging 1997;18(4 Suppl):S81-4.
1997: G Li; M Aryan; Jeremy Silverman; Vahram Haroutunian; Daniel P Perl; S Birstein; Melinda Lantz; Deborah B Marin; Richard C Mohs; Kenneth L Davis
The validity of the family history method for identifying Alzheimer disease.
Archives of neurology 1997;54(5):634-40.
1997: Constantin Bouras; Panteleimon Giannakopoulos; Paul F Good; A Hsu; Patrick R Hof; Daniel P Perl
A laser microprobe mass analysis of brain aluminum and iron in dementia pugilistica: comparison with Alzheimer's disease.
European neurology 1997;38(1):53-8.
1996: Constantin Bouras; Panteleimon Giannakopoulos; Paul F Good; A Hsu; Patrick R Hof; Daniel P Perl
A laser microprobe mass analysis of trace elements in brain mineralizations and capillaries in Fahr's disease.
Acta neuropathologica 1996;92(4):351-7.
1996: D A McKeown; Richard Doty; Daniel P Perl; Richard Eugene Frye; I Simms; A Mester
Olfactory function in young adolescents with Down's syndrome.
Journal of neurology, neurosurgery, and psychiatry 1996;61(4):412-4.
1996: M Mawal-Dewan; M Luise Schmidt; Brian J Balin; Daniel P Perl; Virginia M-Y Lee; John Q Trojanowski
Identification of phosphorylation sites in PHF-TAU from patients with Guam amyotrophic lateral sclerosis/parkinsonism-dementia complex.
Journal of neuropathology and experimental neurology 1996;55(10):1051-9.
1996: Paul F Good; P Werner; A Hsu; C Warren Olanow; Daniel P Perl
Evidence of neuronal oxidative damage in Alzheimer's disease.
The American journal of pathology 1996;149(1):21-8.
1996: C Warren Olanow; Paul F Good; H Shinotoh; K A Hewitt; FJ Vingerhoets; BJ Snow; M Flint Beal; Donald B Calne; Daniel P Perl
Manganese intoxication in the rhesus monkey: a clinical, imaging, pathologic, and biochemical study.
Neurology 1996;46(2):492-8.
1996: S M Gabriel; Michael Davidson; Vahram Haroutunian; Peter Powchik; L M Bierer; Dushyant P Purohit; Daniel P Perl; Kenneth L Davis
Neuropeptide deficits in schizophrenia vs. Alzheimer's disease cerebral cortex.
Biological psychiatry 1996;39(2):82-91.
1996: V Buée Scherrer; Patrick R Hof; Luc BUEE; B Leveugle; Patrick Vermersch; Daniel P Perl; C Warren Olanow; André Delacourte
Hyperphosphorylated tau proteins differentiate corticobasal degeneration and Pick's disease.
Acta neuropathologica 1996;91(4):351-9.
1996: Luc BUEE; Jordi Pérez-Tur; B Leveugle; V Buée-Scherrer; Elliott J Mufson; A J Loerzel; Marie-Christine Chartier-Harlin; Daniel P Perl; André Delacourte; Patrick R Hof
Apolipoprotein E in Guamanian amyotrophic lateral sclerosis/parkinsonism-dementia complex: genotype analysis and relationships to neuropathological changes.
Acta neuropathologica 1996;91(3):247-53.
1996: G Li; Jeremy Silverman; L D Altstiel; Vahram Haroutunian; Daniel P Perl; Dushyant P Purohit; S Birstein; Melinda Lantz; Richard C Mohs; Kenneth L Davis
Apolipoprotein E-epsilon 4 allele and familial risk in Alzheimer's disease.
Genetic epidemiology 1996;13(3):285-98.
1996: THEODORE C IANCU; Daniel P Perl; I Sternlieb; A Lerner; E Leshinsky; E H Kolodny; A Hsu; Paul F Good
The application of laser microprobe mass analysis to the study of biological material.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 1996;9(1):57-65.
1995: THEODORE C IANCU; H Shiloh; Kishor B Raja; R J Simpson; T J Peters; Daniel P Perl; A Hsu; Paul F Good
The hypotransferrinaemic mouse: ultrastructural and laser microprobe analysis observations.
The Journal of pathology 1995;177(1):83-94.
1995: K Horinouchi; S Erlich; Daniel P Perl; Klaus Ferlinz; C L Bisgaier; Konrad Sandhoff; Robert J Desnick; C L Stewart; Edward H Schuchman
Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease.
Nature genetics 1995;10(3):288-93.
1995: H Shinotoh; BJ Snow; K A Hewitt; B D Pate; Doris J Doudet; R Nugent; Daniel P Perl; W Olanow; Donald B Calne
MRI and PET studies of manganese-intoxicated monkeys.
Neurology 1995;45(6):1199-204.
1995: Jeffrey Kordower; T B Freeman; BJ Snow; FJ Vingerhoets; Elliott J Mufson; Paul Sanberg; Robert A Hauser; D A Smith; G M Nauert; Daniel P Perl
Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease.
The New England journal of medicine 1995;332(17):1118-24.
1995: V Buée-Scherrer; Luc BUEE; Patrick R Hof; B Leveugle; C Gilles; A J Loerzel; Daniel P Perl; André Delacourte
Neurofibrillary degeneration in amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam. Immunochemical characterization of tau proteins.
The American journal of pathology 1995;146(4):924-32.
1995: Patrick R Hof; Constantin Bouras; Daniel P Perl; D Larry Sparks; N Mehta; John H Morrison
Age-related distribution of neuropathologic changes in the cerebral cortex of patients with Down's syndrome. Quantitative regional analysis and comparison with Alzheimer's disease.
Archives of neurology 1995;52(4):379-91.
1995: L M Bierer; Vahram Haroutunian; S Gabriel; PJ Knott; L S Carlin; Dushyant P Purohit; Daniel P Perl; James Schmeidler; P Kanof; Kenneth L Davis
Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits.
Journal of neurochemistry 1995;64(2):749-60.
1995: L M Bierer; Patrick R Hof; Dushyant P Purohit; L Carlin; James Schmeidler; Kenneth L Davis; Daniel P Perl
Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease.
Archives of neurology 1995;52(1):81-8.
1994: James C Vickers; John H Morrison; Victor L Friedrich; Gregory A Elder; Daniel P Perl; R N Katz; Robert A Lazzarini
Age-associated and cell-type-specific neurofibrillary pathology in transgenic mice expressing the human midsized neurofilament subunit.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(9):5603-12.
1994: B Leveugle; Geneviève Spik; Daniel P Perl; Constantin Bouras; H M Fillit; Patrick R Hof
The iron-binding protein lactotransferrin is present in pathologic lesions in a variety of neurodegenerative disorders: a comparative immunohistochemical analysis.
Brain research 1994;650(1):20-31.
1994: Patrick R Hof; Daniel P Perl; A J Loerzel; John C Steele; John H Morrison
Amyotrophic lateral sclerosis and parkinsonism-dementia from Guam: differences in neurofibrillary tangle distribution and density in the hippocampal formation and neocortex.
Brain research 1994;650(1):107-16.
1994: Vahram Haroutunian; Michael Davidson; P D Kanof; Daniel P Perl; Peter Powchik; M Losonczy; J McCrystal; Dushyant P Purohit; L M Bierer; Kenneth L Davis
Cortical cholinergic markers in schizophrenia.
Schizophrenia research 1994;12(2):137-44.
1994: S M Gabriel; L M Bierer; Michael Davidson; Dushyant P Purohit; Daniel P Perl; V Harotunian
Galanin-like immunoreactivity is increased in the postmortem cerebral cortex from patients with Alzheimer's disease.
Journal of neurochemistry 1994;62(4):1516-23.
1994: Patrick R Hof; Constantin Bouras; Daniel P Perl; John H Morrison
Quantitative neuropathologic analysis of Pick's disease cases: cortical distribution of Pick bodies and coexistence with Alzheimer's disease.
Acta neuropathologica 1994;87(2):115-24.
1994: D E Lilienfeld; Daniel P Perl
Projected neurodegenerative disease mortality among minorities in the United States, 1990-2040.
Neuroepidemiology 1994;13(4):179-86.
1994: Luc BUEE; Patrick R Hof; Constantin Bouras; André Delacourte; Daniel P Perl; John H Morrison; H M Fillit
Pathological alterations of the cerebral microvasculature in Alzheimer's disease and related dementing disorders.
Acta neuropathologica 1994;87(5):469-80.
1993: L M Bierer; PJ Knott; James Schmeidler; Deborah B Marin; T M Ryan; Vahram Haroutunian; Dushyant P Purohit; Daniel P Perl; Richard C Mohs; Kenneth L Davis
Post-mortem examination of dopaminergic parameters in Alzheimer's disease: relationship to noncognitive symptoms.
Psychiatry research 1993;49(3):211-7.
1993: V F Garry; Paul F Good; J C Manivel; Daniel P Perl
Investigation of a fatality from nonoccupational aluminum phosphide exposure: measurement of aluminum in tissue and body fluids as a marker of exposure.
The Journal of laboratory and clinical medicine 1993;122(6):739-47.
1993: Peter Powchik; Michael Davidson; Charles Nemeroff; Vahram Haroutunian; Dushyant P Purohit; M Losonczy; Garth Bissette; Daniel P Perl; H Ghanbari; B Miller
Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment.
The American journal of psychiatry 1993;150(11):1726-7.
1993: Paul F Good; Daniel P Perl
Laser microprobe mass analysis in Alzheimer's disease.
Annals of neurology 1993;34(3):413-5.
1993: S M Gabriel; L M Bierer; V Harotunian; Dushyant P Purohit; Daniel P Perl; Kenneth L Davis
Widespread deficits in somatostatin but not neuropeptide Y concentrations in Alzheimer's disease cerebral cortex.
Neuroscience letters 1993;155(1):116-20.
1993: Paul F Good; Daniel P Perl
Aluminium in Alzheimer's?
Nature 1993;362(6419):418.
1993: Dushyant P Purohit; Michael Davidson; Daniel P Perl; Peter Powchik; Vahram Haroutunian; L M Bierer; J McCrystal; M Losonczy; Kenneth L Davis
Severe cognitive impairment in elderly schizophrenic patients: a clinicopathological study.
Biological psychiatry 1993;33(4):255-60.
1993: M C Harlin; F Crawford; Daniel P Perl; J Steele; John Hardy
Sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene reveals the beta-amyloid sequence to be normal in cases of the parkinson dementia complex of Guam.
Journal of neural transmission. Parkinson's disease and dementia section 1993;5(1):63-5.
1993: D E Lilienfeld; Daniel P Perl
Projected neurodegenerative disease mortality in the United States, 1990-2040.
Neuroepidemiology 1993;12(4):219-28.
1992: Paul F Good; C Warren Olanow; Daniel P Perl
Neuromelanin-containing neurons of the substantia nigra accumulate iron and aluminum in Parkinson's disease: a LAMMA study.
Brain research 1992;593(2):343-6.
1992: Patrick R Hof; L M Bierer; Daniel P Perl; André Delacourte; Luc BUEE; Constantin Bouras; John H Morrison
Evidence for early vulnerability of the medial and inferior aspects of the temporal lobe in an 82-year-old patient with preclinical signs of dementia. Regional and laminar distribution of neurofibrillary tangles and senile plaques.
Archives of neurology 1992;49(9):946-53.
1992: Patrick R Hof; A Charpiot; André Delacourte; Luc BUEE; Dushyant P Purohit; Daniel P Perl; Constantin Bouras
Distribution of neurofibrillary tangles and senile plaques in the cerebral cortex in postencephalitic parkinsonism.
Neuroscience letters 1992;139(1):10-4.
1992: Paul F Good; Daniel P Perl; L M Bierer; James Schmeidler
Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: a laser microprobe (LAMMA) study.
Annals of neurology 1992;31(3):286-92.
1992: Daniel P Perl; Paul F Good
Comparative techniques for determining cellular iron distribution in brain tissues.
Annals of neurology 1992;32 Suppl():S76-81.
1992: Daniel P Perl; Paul F Good
Aluminium and the neurofibrillary tangle: results of tissue microprobe studies.
Ciba Foundation symposium 1992;169():217-27; discussion 227-36.
1992: Patrick R Hof; Constantin Bouras; Luc BUEE; André Delacourte; Daniel P Perl; John H Morrison
Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases.
Acta neuropathologica 1992;85(1):23-30.
1991: Patrick R Hof; Daniel P Perl; A J Loerzel; John H Morrison
Neurofibrillary tangle distribution in the cerebral cortex of parkinsonism-dementia cases from Guam: differences with Alzheimer's disease.
Brain research 1991;564(2):306-13.
1991: N Perez; J Sugar; S Charya; G Johnson; Carl R Merril; L Bierer; Daniel P Perl; Vahram Haroutunian; W Wallace
Increased synthesis and accumulation of heat shock 70 proteins in Alzheimer's disease.
Brain research. Molecular brain research 1991;11(3-4):249-54.
1991: Richard Doty; Daniel P Perl; J C Steele; K M Chen; J D Pierce; Patricio Reyes; L T Kurland
Olfactory dysfunction in three neurodegenerative diseases.
Geriatrics 1991;46 Suppl 1():47-51.
1991: Richard Doty; Daniel P Perl; J C Steele; K M Chen; J D Pierce; Patricio Reyes; L T Kurland
Odor identification deficit of the parkinsonism-dementia complex of Guam: equivalence to that of Alzheimer's and idiopathic Parkinson's disease.
Neurology 1991;41(5 Suppl 2):77-80; discussion 80-1.
1991: Stephen M Gentleman; Daniel P Perl; D Allsop; J Clinton; MC Royston; G W Roberts
Beta (A4)-amyloid protein and parkinsonian dementia complex of Guam.
Lancet 1991;337(8732):55-6.
1991: K M Parks; J E Sugar; Vahram Haroutunian; L Bierer; Daniel P Perl; W C Wallace
Reduced in vitro phosphorylation of synapsin I (site 1) in Alzheimer's disease postmortem tissues.
Brain research. Molecular brain research 1991;9(1-2):125-34.
1991: Daniel P Perl; Paul F Good
Aluminum, Alzheimer's disease, and the olfactory system.
Annals of the New York Academy of Sciences 1991;640():8-13.
1990: D E Lilienfeld; E Chan; J Ehland; James Godbold; P J Landrigan; G Marsh; Daniel P Perl
Two decades of increasing mortality from Parkinson's disease among the US elderly.
Archives of neurology 1990;47(7):731-4.
1990: L M Bierer; Daniel P Perl; Vahram Haroutunian; Richard C Mohs; Kenneth L Davis
Neurofibrillary tangles, Alzheimer's disease and Lewy bodies.
Lancet 1990;335(8682):163.
1990: D E Lilienfeld; D Sekkor; S Simpson; Daniel P Perl; J Ehland; G Marsh; E Chan; James Godbold; P J Landrigan
Parkinsonism death rates by race, sex and geography: a 1980s update.
Neuroepidemiology 1990;9(5):243-7.
1989: J P Anderson; Lorenzo M Refolo; W Wallace; P Mehta; M Krishnamurthi; J Gotlib; L Bierer; Vahram Haroutunian; Daniel P Perl; Nikolaos K Robakis
Differential brain expression of the Alzheimer's amyloid precursor protein.
The EMBO journal 1989;8(12):3627-32.
1989: Daniel P Perl
Genetics and Alzheimer's disease: notes of an environment watcher (with apologies to L. Thomas).
Neurobiology of aging 1989;10(5):444-6; discussion 446-8.
1989: D S Heller; Michael J Klein; R E Gordon; P Good; Daniel P Perl
Intraosseous beta-2-microglobulin amyloidosis. Detection and measurement of osseous aluminum in a patient who was receiving long-term hemodialysis.
The Journal of bone and joint surgery. American volume 1989;71(7):1083-9.
1989: WW Pendlebury; Daniel P Perl; D G Munoz
Multiple microabscesses in the central nervous system: a clinicopathologic study.
Journal of neuropathology and experimental neurology 1989;48(3):290-300.
1989: D E Lilienfeld; E Chan; J Ehland; James Godbold; P J Landrigan; G Marsh; Daniel P Perl
Rising mortality from motoneuron disease in the USA, 1962-84.
Lancet 1989;1(8640):710-3.
1989: Neil W Kowall; WW Pendlebury; J B Kessler; Daniel P Perl; M Flint Beal
Aluminum-induced neurofibrillary degeneration affects a subset of neurons in rabbit cerebral cortex, basal forebrain and upper brainstem.
Neuroscience 1989;29(2):329-37.
1988: WW Pendlebury; Daniel P Perl; A Schwentker; T M Pingree; Paul R Solomon
Aluminum-induced neurofibrillary degeneration disrupts acquisition of the rabbit's classically conditioned nictitating membrane response.
Behavioral neuroscience 1988;102(5):615-20.
1988: David G Munoz; C Greene; Daniel P Perl; Dennis J Selkoe
Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients.
Journal of neuropathology and experimental neurology 1988;47(1):9-18.
1988: Paul R Solomon; T M Pingree; D Baldwin; D Koota; Daniel P Perl; WW Pendlebury
Disrupted retention of the classically conditioned nictitating membrane response in rabbits with aluminum-induced neurofibrillary degeneration.
Neurotoxicology 1988;9(2):209-21.
1987: David Eidelberg; A Sotrel; Catherine Joachim; Dennis J Selkoe; A Forman; W W Pendlebury; Daniel P Perl
Adult onset Hallervorden-Spatz disease with neurofibrillary pathology. A discrete clinicopathological entity.
Brain : a journal of neurology 1987;110 ( Pt 4)():993-1013.
1987: Daniel P Perl; Paul F Good
Uptake of aluminium into central nervous system along nasal-olfactory pathways.
Lancet 1987;1(8540):1028.
1987: D G Muñoz; Daniel P Perl; W W Pendlebury; R A Highland
Comparison of cytomegalovirus infection of brain and lung in a patient with subacute encephalopathy of acquired immunodeficiency syndrome.
Archives of pathology & laboratory medicine 1987;111(3):234-7.
1987: WW Pendlebury; D Munoz-Garcia; Daniel P Perl
Cytoskeletal pathology in neurodegenerative diseases.
Advances in experimental medicine and biology 1987;221():427-42.
1987: Daniel P Perl; Paul F Good
The association of aluminum Alzheimer's disease, and neurofibrillary tangles.
Journal of neural transmission. Supplementum 1987;24():205-11.
1986: Daniel P Perl; W W Pendlebury
Aluminum neurotoxicity--potential role in the pathogenesis of neurofibrillary tangle formation.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1986;13(4 Suppl):441-5.
1986: B W Little; P W Brown; P Rodgers-Johnson; Daniel P Perl; D Carleton Gajdusek
Familial myoclonic dementia masquerading as Creutzfeldt-Jakob disease.
Annals of neurology 1986;20(2):231-9.
1986: Daniel P Perl; W W Pendlebury
Neuropathology of dementia.
Neurologic clinics 1986;4(2):355-68.
1986: D Munoz-Garcia; WW Pendlebury; J B Kessler; Daniel P Perl
An immunocytochemical comparison of cytoskeletal proteins in aluminum-induced and Alzheimer-type neurofibrillary tangles.
Acta neuropathologica 1986;70(3-4):243-8.
1985: Daniel P Perl
Relationship of aluminum to Alzheimer's disease.
Environmental health perspectives 1985;63():149-53.
1985: R A Goyer; J Bachmann; T W Clarkson; B G Ferris; J Graham; P Mushak; Daniel P Perl; D P Rall; R Schlesinger; W Sharpe
Potential human health effects of acid rain: report of a workshop.
Environmental health perspectives 1985;60():355-68.
1983: W W Pendlebury; Daniel P Perl; W C Winn; J B McQuillen
Neuropathologic evaluation of 40 confirmed cases of Legionella pneumonia.
Neurology 1983;33(10):1340-4.
1982: Daniel P Perl; D Carleton Gajdusek; R M Garruto; R T Yanagihara; C J Gibbs
Intraneuronal aluminum accumulation in amyotrophic lateral sclerosis and Parkinsonism-dementia of Guam.
Science (New York, N.Y.) 1982;217(4564):1053-5.
1980: Daniel P Perl; A R Brody
Alzheimer's disease: X-ray spectrometric evidence of aluminum accumulation in neurofibrillary tangle-bearing neurons.
Science (New York, N.Y.) 1980;208(4441):297-9.
1975: S M Aronson; Daniel P Perl
Clinical neuropathological conference.
Diseases of the nervous system 1975;36(8):429-34.
1974: S M Aronson; Daniel P Perl
Clinical neuropathological conference.
Diseases of the nervous system 1974;35(10):484-7.
1974: S M Aronson; Daniel P Perl
Clinical neuropathological conference. A 58-year-old concrete worker was amitted to the hospital because of slowly progressive dementia.
Diseases of the nervous system 1974;35(6):286-91.
1974: S M Aronson; Daniel P Perl
Clinical neuropathological conference. The patient was a 72-year-old white male who was admitted to the hospital because of lower back pain. About 8 months before admission he noted chills and fever.
Diseases of the nervous system 1974;35(3):116-9.
1974: S M Aronson; Daniel P Perl
Clinical neuropathological conference. A 3-year-old girl was admitted to the hospital shortly after suffering an accidental burn.
Diseases of the nervous system 1974;35(2):91-6.
1973: A F Kaufmann; G W Gary; J R Broderson; Daniel P Perl; K D Quist; R E Kissling
Simian virus 16 associated with an epizootic of obscure neurologic disease.
Laboratory animal science 1973;23(6):812-8.