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Carlo Federico Perno

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

HIV-1
HIV

Disorders

HIV Infections

Chemicals & Drugs

Anatomy

Physiology

Procedures

Highly Active Antiretroviral Therapy

Concepts & Ideas

Viral Load

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Publications

TOP 3
Puzelli Simona; Valdarchi Catia; Ciotti Marco; Dorrucci Maria; Farchi Francesca; Babakir-Mina Muhammed; Perno Carlo Federico; Donatelli Isabella; Rezza Giovanni;
Viral causes of influenza-like illness: Insight from a study during the winters 2004-2007.
Bergallo Massimiliano; Terlizzi Maria Elena; Astegiano Sara; Ciotti Marco; Babakir-Mina Muhammed; Perno Carlo Federico; Cavallo Rossana; Costa Cristina
Real time PCR TaqMan assays for detection of polyomaviruses KIV and WUV in clinical samples.
Soriano Vincent; Perno Carlo-Federico; Kaiser Rolf; Calvez Vincent; Gatell Jose M; di Perri Giovanni; Pillay Deenan; Rockstroh Juergen; Geretti Anna María
When and how to use maraviroc in HIV-infected patients.

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All Publications

2009: Puzelli Simona; Valdarchi Catia; Ciotti Marco; Dorrucci Maria; Farchi Francesca; Babakir-Mina Muhammed; Perno Carlo Federico; Donatelli Isabella; Rezza Giovanni;
Viral causes of influenza-like illness: Insight from a study during the winters 2004-2007.
Journal of medical virology 2009;81(12):2066-71.
2009: Bergallo Massimiliano; Terlizzi Maria Elena; Astegiano Sara; Ciotti Marco; Babakir-Mina Muhammed; Perno Carlo Federico; Cavallo Rossana; Costa Cristina
Real time PCR TaqMan assays for detection of polyomaviruses KIV and WUV in clinical samples.
Journal of virological methods 2009;162(1-2):69-74.
2009: Soriano Vincent; Perno Carlo-Federico; Kaiser Rolf; Calvez Vincent; Gatell Jose M; di Perri Giovanni; Pillay Deenan; Rockstroh Juergen; Geretti Anna María
When and how to use maraviroc in HIV-infected patients.
AIDS (London, England) 2009;23(18):2377-85.
2009: Cento Valeria; Ciccozzi Massimo; Ronga Luigi; Perno Carlo Federico; Ciotti Marco
Genetic diversity of human papillomavirus type 16 E6, E7, and L1 genes in Italian women with different grades of cervical lesions.
Journal of medical virology 2009;81(9):1627-34.
2009: Babakir-Mina Muhammed; Ciccozzi Massimo; Alteri Claudia; Polchi Paola; Picardi Alessandra; Greco Francesco; Lucarelli Guido; Arcese William; Perno Carlo Federico; Ciotti Marco
Excretion of the novel polyomaviruses KI and WU in the stool of patients with hematological disorders.
Journal of medical virology 2009;81(9):1668-73.
2009: Babakir-Mina Muhammed; Ciccozzi Massimo; Bonifacio Daniela; Bergallo Massimiliano; Costa Cristina; Cavallo Rossana; Di Bonito Luigi; Perno Carlo Federico; Ciotti Marco
Identification of the novel KI and WU polyomaviruses in human tonsils.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2009;46(1):75-9.
2009: Babakir-Mina Muhammed; Ciccozzi Massimo; Trento Elisabetta; Perno Carlo Federico; Ciotti Marco
KI and WU polyomaviruses in patients infected with HIV-1, Italy.
Emerging infectious diseases 2009;15(8):1323-5.
2009: Puertas Maria Carmen; Buzón Maria Jose; Artese Anna; Alcaro Stefano; Menendez-Arias Luis; Perno Carlo Federico; Clotet Bonaventura; Ceccherini-Silberstein Francesca; Martinez-Picado Javier
Effect of the human immunodeficiency virus type 1 reverse transcriptase polymorphism Leu-214 on replication capacity and drug susceptibility.
Journal of virology 2009;83(15):7434-9.
2009: Alcaro Stefano; Artese Anna; Ceccherini-Silberstein Francesca; Ortuso Francesco; Perno Carlo Federico; Sing Tobias; Svicher Valentina
Molecular dynamics and free energy studies on the wild-type and mutated HIV-1 protease complexed with four approved drugs: mechanism of binding and drug resistance.
Journal of chemical information and modeling 2009;49(7):1751-61.
2009: Svicher Valentina; Alteri Claudia; D'Arrigo Roberta; Laganà Alessandro; Trignetti Maria; Lo Caputo Sergio; Callegaro Anna Paola; Maggiolo Franco; Mazzotta Francesco; Ferro Alfredo; Dimonte Salvatore; Aquaro Stefano; di Perri Giovanni; Bonora Stefano; Tommasi Chiara; Trotta Maria Paola; Narciso Pasquale; Antinori Andrea; Perno Carlo Federico; Ceccherini-Silberstein Francesca
Treatment with the fusion inhibitor enfuvirtide influences the appearance of mutations in the human immunodeficiency virus type 1 regulatory protein rev.
Antimicrobial agents and chemotherapy 2009;53(7):2816-23.
2009: Zaccarelli M; Lorenzini P; Tozzi V; Forbici F; Ceccherini-Silberstein F; Gori C; D'Arrigo R; Trotta M P; Narciso P; Perno C F; Antinori A;
Effect of suppressing HIV viremia on the HIV progression of patients undergoing a genotype resistance test after treatment failure.
Infection 2009;37(3):203-9.
2009: Polilli Ennio; Di Masi Francesco; Sozio Federica; Mazzotta Elena; Alterio Luciana; Cosentino Luana; Clerico Luigi; Perno Carlo Federico; Parruti Giustino
Sequential transmission and long-term persistence of an HIV strain partially resistant to protease inhibitors.
The new microbiologica : official journal of the Italian Society for Medical, Odontoiatric, and Clinical Microbiology (SIMMOC) 2009;32(2):205-8.
2009: Babakir-Mina Muhammed; Ciccozzi Massimo; Campitelli Laura; Aquaro Stefano; Lo Coco Achille; Perno Carlo Federico; Ciotti Marco
Identification of the novel KI Polyomavirus in paranasal and lung tissues.
Journal of medical virology 2009;81(3):558-61.
2009: Agarossi Alberto; Ferrazzi Enrico; Parazzini Fabio; Perno Carlo Federico; Ghisoni Luciano
Prevalence and type distribution of high-risk human papillomavirus infection in women undergoing voluntary cervical cancer screening in Italy.
Journal of medical virology 2009;81(3):529-35.
2009: Svicher Valentina; Gori Caterina; Trignetti Maria; Visca Michela; Micheli Valeria; Bernassola Martina; Salpini Romina; Gubertini Guido; Longo Roberta; Niero Fosca; Ceccherini-Silberstein Francesca; De Sanctis Giuseppe Maria; Spanò Alberto; Cappiello Giuseppina; Perno Carlo Federico
The profile of mutational clusters associated with lamivudine resistance can be constrained by HBV genotypes.
Journal of hepatology 2009;50(3):461-70.
2009: Capetti Amedeo Ferdinando; Piconi Stefania; Landonio Simona; Rizzardini Giuliano; Perno Carlo Federico
Is dual therapy with raltegravir and protease inhibitors a feasible option in rescue strategy in HIV-1 infection?
Journal of acquired immune deficiency syndromes (1999) 2009;50(2):233-4.
2009: Giuliani M; Montieri S; Palamara G; Latini A; Alteri C; Perno C F; Santoro M M; Rezza G; Ciccozzi M
Non-B HIV type 1 subtypes among men who have sex with men in Rome, Italy.
AIDS research and human retroviruses 2009;25(2):157-64.
2009: Ceccherini-Silberstein Francesca; Malet Isabelle; D'Arrigo Roberta; Antinori Andrea; Marcelin Anne-Genevieve; Perno Carlo-Federico
Characterization and structural analysis of HIV-1 integrase conservation.
AIDS reviews 2009;11(1):17-29.
2009: Trignetti Maria; Sing Tobias; Svicher Valentina; Santoro Maria Mercedes; Forbici Federica; D'arrigo Roberta; Bellocchi Maria Concetta; Santoro Mario; Marconi Patrizia; Zaccarelli Mauro; Trotta Maria Paola; Bellagamba Rita; Narciso Pasquale; Antinori Andrea; Lengauer Thomas; Perno Carlo Federico; Ceccherini-Silberstein Francesca
Dynamics of NRTI resistance mutations during therapy interruption.
AIDS research and human retroviruses 2009;25(1):57-64.
2009: Alteri Claudia; Svicher Valentina; Gori Caterina; D'Arrigo Roberta; Ciccozzi Massimo; Ceccherini-Silberstein Francesca; Selleri Marina; Bardacci Stefano Aviani; Giuliani Massimo; Elia Paola; Scognamiglio Paola; Balzano Roberta; Orchi Nicoletta; Girardi Enrico; Perno Carlo Federico;
Characterization of the patterns of drug-resistance mutations in newly diagnosed HIV-1 infected patients naïve to the antiretroviral drugs.
BMC infectious diseases 2009;9():111.
2009: Babakir-Mina Muhammed; Dimonte Salvatore; Perno Carlo Federico; Ciotti Marco
Origin of the 2009 Mexico influenza virus: a comparative phylogenetic analysis of the principal external antigens and matrix protein.
Archives of virology 2009;154(8):1349-52.
2009: Pollicita Michela; Muscoli Carolina; Sgura Antonella; Biasin Alberto; Granato Teresa; Masuelli Laura; Mollace Vincenzo; Tanzarella Caterina; Del Duca Claudio; Rodinò Paola; Perno Carlo Federico; Aquaro Stefano
Apoptosis and telomeres shortening related to HIV-1 induced oxidative stress in an astrocytoma cell line.
BMC neuroscience 2009;10():51.
2009: Ciotti Marco; Marzano Valeria; Giuliani Laura; Nuccetelli Marzia; D'Aguanno Simona; Azzimonti Barbara; Bernardini Sergio; Perno Carlo Federico; Urbani Andrea; Favalli Cartesio; Federici Giorgio
Proteomic investigation in A549 lung cell line stably infected by HPV16E6/E7 oncogenes.
Respiration; international review of thoracic diseases 2009;77(4):427-39.
2008: Soriano Vincent; Geretti Anna María; Perno Carlo-Federico; Fätkenheuer Gerd; Pillay Deenan; Reynes Jacques; Tambussi Giuseppe; Calvez Vincent; Alcamí José; Rockstroh Juergen
Optimal use of maraviroc in clinical practice.
AIDS (London, England) 2008;22(17):2231-40.
2008: Babakir-Mina Muhammed; Ciccozzi Massimo; Dimonte Salvatore; Farchi Francesca; Valdarchi Catia; Rezza Giovanni; Perno Carlo Federico; Ciotti Marco
Identification of the novel KI polyomavirus in the respiratory tract of an Italian patient.
Journal of medical virology 2008;80(11):2012-4.
2008: Santoro Maria Mercedes; Ciccozzi Massimo; Alteri Claudia; Montieri Stefania; Alexiev Ivailo; Dimova Iordanka; Ceccherini-Silberstein Francesca; Beshkov Danail; Rezza Giovanni; Perno Carlo Federico
Characterization of drug-resistance mutations in HIV type 1 isolates from drug-naive and ARV-treated patients in Bulgaria.
AIDS research and human retroviruses 2008;24(9):1133-8.
2008: Tozzi Valerio; Bellagamba Rita; Castiglione Filippo; Amendola Alessanda; Ivanovic Jelena; Nicastri Emanuele; Libertone Raffaella; D'Offizi Giampiero; Liuzzi Giuseppina; Gori Caterina; Forbici Federica; D'Arrigo Roberta; Bertoli Ada; Salvatori Maria Flora; Capobianchi Maria Rosaria; Antinori Andrea; Perno Carlo Federico; Narciso Pasquale
Plasma HIV RNA decline and emergence of drug resistance mutations among patients with multiple virologic failures receiving resistance testing-guided HAART.
AIDS research and human retroviruses 2008;24(6):787-96.
2008: Moyle Graeme; Gatell Jose; Perno Carlo-Federico; Ratanasuwan Winai; Schechter Mauro; Tsoukas Christos
Potential for new antiretrovirals to address unmet needs in the management of HIV-1 infection.
AIDS patient care and STDs 2008;22(6):459-71.
2008: Svicher Valentina; Aquaro Stefano; D'Arrigo Roberta; Artese Anna; Dimonte Salvatore; Alcaro Stefano; Santoro Maria Mercedes; Di Perri Giovanni; Caputo Sergio Lo; Bellagamba Rita; Zaccarelli Mauro; Visco-Comandini Ubaldo; Antinori Andrea; Narciso Pasquale; Ceccherini-Silberstein Francesca; Perno Carlo-Federico
Specific enfuvirtide-associated mutational pathways in HIV-1 Gp41 are significantly correlated with an increase in CD4(+) cell count, despite virological failure.
The Journal of infectious diseases 2008;197(10):1408-18.
2008: Perno Carlo-Federico; Moyle Graeme; Tsoukas Chris; Ratanasuwan Winai; Gatell Jose; Schechter Mauro
Overcoming resistance to existing therapies in HIV-infected patients: the role of new antiretroviral drugs.
Journal of medical virology 2008;80(4):565-76.
2008: Ciotti Marco; Marcuccilli Fabbio; Guenci Tania; Prignano Maria Grazia; Perno Carlo Federico
Evaluation of the Abbott RealTime HBV DNA assay and comparison to the Cobas AmpliPrep/Cobas TaqMan 48 assay in monitoring patients with chronic cases of hepatitis B.
Journal of clinical microbiology 2008;46(4):1517-9.
2008: Giuliani Laura; Ronci Corrado; Bonifacio Daniela; Di Bonito Luigi; Favalli Cartesio; Perno Carlo Federico; Syrjänen Kari; Ciotti Marco
Detection of oncogenic DNA viruses in colorectal cancer.
Anticancer research 2008;28(2B):1405-10.
2008: Zaccarelli M; Marconi P; Visco-Comandini U; Liuzzi G; Sette P; Acinapura R; Mosti S; Ammassari A; Perno C F; Antinori A
Evidence of dual sexual transmission of multi-resistant HIV with two years persistence of resistance to NRTI and NNRTI: a case report.
Infection 2008;36(2):178-80.
2008: Santoro Maria Mercedes; Bertoli Ada; Lorenzini Patrizia; Lazzarin Adriano; Esposito Roberto; Carosi Giampiero; Di Perri Giovanni; Filice Gaetano; Moroni Mauro; Rizzardini Giuliano; Caramello Pietro; Maserati Renato; Narciso Pasquale; Cargnel Antonietta; Antinori Andrea; Perno Carlo Federico;
Viro-immunologic response to ritonavir-boosted or unboosted atazanavir in a large cohort of multiply treated patients: the CARe Study.
AIDS patient care and STDs 2008;22(1):7-16.
2008: Pollicita M; Schols D; Aquaro S; Peumans W J; Van Damme E J M; Perno C F; Balzarini J
Carbohydrate-binding agents (CBAs) inhibit HIV-1 infection in human primary monocyte-derived macrophages (MDMs) and efficiently prevent MDM-directed viral capture and subsequent transmission to CD4+ T lymphocytes.
Virology 2008;370(2):382-91.
2007: De Luca Andrea; Giambenedetto Simona Di; Trotta Maria Paola; Colafigli Manuela; Prosperi Mattia; Ruiz Lidia; Baxter John; Clevenbergh Philippe; Cauda Roberto; Perno Carlo-Federico; Antinori Andrea
Improved interpretation of genotypic changes in the HIV-1 reverse transcriptase coding region that determine the virological response to didanosine.
The Journal of infectious diseases 2007;196(11):1645-53.
2007: Marazzi Cristina M; Germano Paola; Liotta Giuseppe; Guidotti Giovanni; Loureiro Sandra; Gomes Aurelio da Cruz; Blazquez Maria C Valls; Narciso Pasquale; Perno Carlo F; Mancinelli Sandro; Altan Annamaria Doro; Nielsen-Saines Karin; Palombi Leonardo
Implementing anti-retroviral triple therapy to prevent HIV mother-to-child transmission: a public health approach in resource-limited settings.
European journal of pediatrics 2007;166(12):1305-7.
2007: D'Arrigo Roberta; Ciccozzi Massimo; Gori Caterina; Montieri Stefania; Aquaro Stefano; Bellagamba Rita; Boumis Evangelo; Di Perri Giovanni; Pizzi Daniele; Antinori Andrea; Rezza Giovanni; Perno Carlo Federico
gp41 sequence variability in HIV type 1 non-B subtypes infected patients undergoing enfuvirtide pressure.
AIDS research and human retroviruses 2007;23(10):1296-302.
2007: Ceccherini-Silberstein Francesca; Cozzi-Lepri Alessandro; Ruiz Lidia; Mocroft Amanda; Phillips Andrew N; Olsen Christian Holkmann; Gatell Jose M; Gunthard Huldrych F; Reiss Peter; Perno Carlo Federico; Clotet Bonaventura; Lundgren Jens D;
Impact of HIV-1 reverse transcriptase polymorphism F214L on virological response to thymidine analogue-based regimens in antiretroviral therapy (ART)-naive and ART-experienced patients.
The Journal of infectious diseases 2007;196(8):1180-90.
2007: Ceccherini-Silberstein Francesca; Svicher Valentina; Sing Tobias; Artese Anna; Santoro Maria Mercedes; Forbici Federica; Bertoli Ada; Alcaro Stefano; Palamara Guido; d'Arminio Monforte Antonella; Balzarini Jan; Antinori Andrea; Lengauer Thomas; Perno Carlo Federico
Characterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of resistance to nonnucleoside inhibitors.
Journal of virology 2007;81(20):11507-19.
2007: Franzese Ornella; Adamo Riccardo; Pollicita Michela; Comandini Alessandro; Laudisi Anastasia; Perno Carlo Federico; Aquaro Stefano; Bonmassar Enzo
Telomerase activity, hTERT expression, and phosphorylation are downregulated in CD4(+) T lymphocytes infected with human immunodeficiency virus type 1 (HIV-1).
Journal of medical virology 2007;79(5):639-46.
2007: Babakir-Mina Muhammed; Balestra Emanuela; Perno Carlo Federico; Aquaro Stefano
Influenza virus A (H5N1): a pandemic risk?
The new microbiologica : official journal of the Italian Society for Medical, Odontoiatric, and Clinical Microbiology (SIMMOC) 2007;30(2):65-78.
2007: Rossi Luigia; Franchetti Palmarisa; Pierigé Francesca; Cappellacci Loredana; Serafini Sonja; Balestra Emanuela; Perno Carlo-Federico; Grifantini Mario; Caliò Raffaele; Magnani Mauro
Inhibition of HIV-1 replication in macrophages by a heterodinucleotide of lamivudine and tenofovir.
The Journal of antimicrobial chemotherapy 2007;59(4):666-75.
2007: Stevens Miguel; Pollicita Michela; Pannecouque Christophe; Verbeken Erik; Tabarrini Oriana; Cecchetti Violetta; Aquaro Stefano; Perno Carlo Federico; Fravolini Arnaldo; De Clercq Erik; Schols Dominique; Balzarini Jan
Novel in vivo model for the study of human immunodeficiency virus type 1 transcription inhibitors: evaluation of new 6-desfluoroquinolone derivatives.
Antimicrobial agents and chemotherapy 2007;51(4):1407-13.
2007: Antinori Andrea; Trotta Maria Paola; Lorenzini Patrizia; Torti Carlo; Gianotti Nicola; Maggiolo Franco; Ceccherini-Silberstein Francesca; Nasto Paola; Castagna Antonella; De Luca Andrea; Mussini Cristina; Andreoni Massimo; Perno Carlo Federico;
Virological response to salvage therapy in HIV-infected persons carrying the reverse transcriptase K65R mutation.
Antiviral therapy 2007;12(8):1175-83.
2007: Pollicita Michela; Ruff Michael R; Pert Candace B; Polianova Maria T; Schols Dominique; Ranazzi Alessandro; Perno Carlo-Federico; Aquaro Stefano
Profound anti-HIV-1 activity of DAPTA in monocytes/macrophages and inhibition of CCR5-mediated apoptosis in neuronal cells.
Antiviral chemistry & chemotherapy 2007;18(5):285-95.
2007: Aquaro Stefano; Muscoli Carolina; Ranazzi Alessandro; Pollicita Michela; Granato Teresa; Masuelli Laura; Modesti Andrea; Perno Carlo-Federico; Mollace Vincenzo
The contribution of peroxynitrite generation in HIV replication in human primary macrophages.
Retrovirology 2007;4():76.
2007: Zaccarelli Mauro; Tozzi Valerio; Lorenzini Patrizia; Forbici Federica; Narciso Pasquale; Ceccherini-Silberstein Francesca; Trotta Maria Paola; Bertoli Ada; Liuzzi Giuseppina; Marconi Patrizia; Mosti Silvia; Perno Carlo Federico; Antinori Andrea
The V118I mutation as a marker of advanced HIV infection and disease progression.
Antiviral therapy 2007;12(2):163-8.
2006: Aquaro Stefano; Svicher Valentina; Perno Carlo Federico
Does residual virus replication during successful HAART lead to HIV-1 genetic evolution?
Journal of HIV therapy 2006;11(4):84-8.
2006: de Oliveira Tulio; Pybus Oliver G; Rambaut Andrew; Salemi Marco; Cassol Sharon; Ciccozzi Massimo; Rezza Giovanni; Gattinara Guido Castelli; D'Arrigo Roberta; Amicosante Massimo; Perrin Luc; Colizzi Vittorio; Perno Carlo Federico;
Molecular epidemiology: HIV-1 and HCV sequences from Libyan outbreak.
Nature 2006;444(7121):836-7.
2006: Cervasi B; Paiardini M; Serafini S; Fraternale A; Menotta M; Engram J; Lawson B; Staprans S I; Piedimonte G; Perno C F; Silvestri G; Magnani M
Administration of fludarabine-loaded autologous red blood cells in simian immunodeficiency virus-infected sooty mangabeys depletes pSTAT-1-expressing macrophages and delays the rebound of viremia after suspension of antiretroviral therapy.
Journal of virology 2006;80(21):10335-45.
2006: Montaner Luis J; Crowe Suzanne M; Aquaro Stefano; Perno Carlo-Federico; Stevenson Mario; Collman Ronald G
Advances in macrophage and dendritic cell biology in HIV-1 infection stress key understudied areas in infection, pathogenesis, and analysis of viral reservoirs.
Journal of leukocyte biology 2006;80(5):961-4.
2006: Aquaro Stefano; Svicher Valentina; Schols Dominique; Pollicita Michela; Antinori Andrea; Balzarini Jan; Perno Carlo Federico
Mechanisms underlying activity of antiretroviral drugs in HIV-1-infected macrophages: new therapeutic strategies.
Journal of leukocyte biology 2006;80(5):1103-10.
2006: Perno Carlo Federico; Svicher Valentina; Ceccherini-Silberstein Francesca
Novel drug resistance mutations in HIV: recognition and clinical relevance.
AIDS reviews 2006;8(4):179-90.
2006: Aquaro Stefano; D'Arrigo Roberta; Svicher Valentina; Perri Giovanni Di; Caputo Sergio Lo; Visco-Comandini Ubaldo; Santoro Mario; Bertoli Ada; Mazzotta Francesco; Bonora Stefano; Tozzi Valerio; Bellagamba Rita; Zaccarelli Mauro; Narciso Pasquale; Antinori Andrea; Perno Carlo Federico
Specific mutations in HIV-1 gp41 are associated with immunological success in HIV-1-infected patients receiving enfuvirtide treatment.
The Journal of antimicrobial chemotherapy 2006;58(4):714-22.
2006: Perno Carlo Federico; Svicher Valentina; Schols Dominique; Pollicita Michela; Balzarini Jan; Aquaro Stefano
Therapeutic strategies towards HIV-1 infection in macrophages.
Antiviral research 2006;71(2-3):293-300.
2006: Marchetti Giulia; Gori Andrea; Casabianca Anna; Magnani Mauro; Franzetti Fabio; Clerici Mario; Perno Carlo-Federico; Monforte Antonella d'Arminio; Galli Massimo; Meroni Luca
Comparative analysis of T-cell turnover and homeostatic parameters in HIV-infected patients with discordant immune-virological responses to HAART.
AIDS (London, England) 2006;20(13):1727-36.
2006: Marazzi M C; Germano P; Liotta G; Guidotti G; Loureiro S; da Cruz Gomes A; Valls Blazquez M C; Narciso P; Perno C F; Mancinelli S; Palombi L
Safety of nevirapine-containing antiretroviral triple therapy regimens to prevent vertical transmission in an African cohort of HIV-1-infected pregnant women.
HIV medicine 2006;7(5):338-44.
2006: Svicher Valentina; Sing Tobias; Santoro Maria Mercedes; Forbici Federica; Rodríguez-Barrios Fátima; Bertoli Ada; Beerenwinkel Niko; Bellocchi Maria Concetta; Gago Federigo; d'Arminio Monforte Antonella; Antinori Andrea; Lengauer Thomas; Ceccherini-Silberstein Francesca; Perno Carlo Federico
Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors.
Journal of virology 2006;80(14):7186-98.
2006: Larussa Dora; Lorenzini Patrizia; Cingolani Antonella; Bossolasco Simona; Grisetti Susanna; Bongiovanni Marco; Moretti Francesca; Uccella Ilaria; Zannoni Paolo; Foresti Sergio; Mazzarello Giovanni; Arcidiacono Maria Irene; Pedale Rosa; Ammassari Adriana; Tozzi Valerio; Perno Carlo Federico; Monforte Antonella D'Arminio; Cinque Paola; Antinori Andrea;
Highly active antiretroviral therapy reduces the age-associated risk of dementia in a cohort of older HIV-1-infected patients.
AIDS research and human retroviruses 2006;22(5):386-92.
2006: Santoro Maria Mercedes; Svicher Valentina; Gori Caterina; Zaccarelli Mauro; Tozzi Valerio; Forbici Federica; D'Arrigo Roberta; Trotta Maria Paola; Bellocchi Maria Concetta; Visco-Comandini Ubaldo; Cenci Alessandra; Bertoli Ada; Narciso Pasquale; Antinori Andrea; Perno Carlo Federico; Ceccherini-Silberstein Francesca
Temporal characterization of drug resistance associated mutations in HIV-1 protease and reverse transcriptase in patients failing antiretroviral therapy.
The new microbiologica : official journal of the Italian Society for Medical, Odontoiatric, and Clinical Microbiology (SIMMOC) 2006;29(2):89-100.
2006: Casoli Claudio; Pilotti Elisabetta; Perno Carlo Federico; Balestra Emanuela; Polverini Eugenia; Cassone Antonio; Conti Stefania; Magliani Walter; Polonelli Luciano
A killer mimotope with therapeutic activity against AIDS-related opportunistic micro-organisms inhibits ex-vivo HIV-1 replication.
AIDS (London, England) 2006;20(7):975-80.
2006: Marazzi M C; Bartolo M; Emberti Gialloreti L; Germano P; Guidotti G; Liotta G; Magnano San Lio M; Mancinelli S; Modolo M A; Narciso P; Perno C F; Scarcella P; Tintisona G; Palombi L
Improving adherence to highly active anti-retroviral therapy in Africa: the DREAM programme in Mozambique.
Health education research 2006;21(1):34-42.
2006: Tozzi Valerio; Zaccarelli Mauro; Bonfigli Sandro; Lorenzini Patrizia; Liuzzi Giuseppina; Trotta Maria Paola; Forbici Federica; Gori Caterina; Bertoli Ada; Bellagamba Rita; Narciso Pasquale; Perno Carlo Federico; Antinori Andrea;
Drug-class-wide resistance to antiretrovirals in HIV-infected patients failing therapy: prevalence, risk factors and virological outcome.
Antiviral therapy 2006;11(5):553-60.
2006: Antinori Andrea; Trotta Maria Paola; Nasta Paola; Bini Teresa; Bonora Stefano; Castagna Antonella; Zaccarelli Mauro; Quirino Tiziana; Landonio Simona; Merli Stefania; Tozzi Valerio; Di Perri Giovanni; Andreoni Massimo; Perno Carlo Federico; Carosi Giampiero
Antiviral efficacy and genotypic resistance patterns of combination therapy with stavudine/tenofovir in highly active antiretroviral therapy experienced patients.
Antiviral therapy 2006;11(2):233-43.
2005: Antinori Andrea; Perno Carlo Federico; Giancola Maria Letizia; Forbici Federica; Ippolito Giuseppe; Hoetelmans Richard M; Piscitelli Stephen C
Efficacy of cerebrospinal fluid (CSF)-penetrating antiretroviral drugs against HIV in the neurological compartment: different patterns of phenotypic resistance in CSF and plasma.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;41(12):1787-93.
2005: Antinori Andrea; Cingolani Antonella; Perno Carlo Federico
Structured treatment interruption in HIV-infected patients failing on multidrug therapy: is there a future for this strategy?
AIDS (London, England) 2005;19(15):1691-4.
2005: Auwerx Joeri; Rodríguez-Barrios Fátima; Ceccherini-Silberstein Francesca; San-Félix Ana; Velázquez Sonsoles; De Clercq Erik; Camarasa María-José; Perno Carlo-Federico; Gago Federico; Balzarini Jan
The role of Thr139 in the human immunodeficiency virus type 1 reverse transcriptase sensitivity to (+)-calanolide A.
Molecular pharmacology 2005;68(3):652-9.
2005: Ceccherini-Silberstein Francesca; Gago Federico; Santoro Maria; Gori Caterina; Svicher Valentina; Rodríguez-Barrios Fátima; d'Arrigo Roberta; Ciccozzi Massimo; Bertoli Ada; d'Arminio Monforte Antonella; Balzarini Jan; Antinori Andrea; Perno Carlo-Federico
High sequence conservation of human immunodeficiency virus type 1 reverse transcriptase under drug pressure despite the continuous appearance of mutations.
Journal of virology 2005;79(16):10718-29.
2005: Ciccozzi Massimo; Gori Caterina; Boros Stefano; Ruiz-Alvarez Maria Jose; Harxhi Arjan; Dervishi Marjeta; Qyra Shpetim; Schinaia Nicola; D'Arrigo Roberta; Ceccherini-Silberstein Francesca; Bino Silva; Perno Carlo Federico; Rezza Giovanni
Molecular diversity of HIV in Albania.
The Journal of infectious diseases 2005;192(3):475-9.
2005: Bellocchi Maria Concetta; Forbici Federica; Palombi Leonardo; Gori Caterina; Coelho Elisabeth; Svicher Valentina; D'Arrigo Roberta; Emberti-Gialloreti Leonardo; Ceffa Susanna; Erba Fulvio; Marazzi Maria Cristina; Silberstein Francesca Ceccherini; Perno Carlo-Federico
Subtype analysis and mutations to antiviral drugs in HIV-1-infected patients from Mozambique before initiation of antiretroviral therapy: results from the DREAM programme.
Journal of medical virology 2005;76(4):452-8.
2005: Zaccarelli Mauro; Tozzi Valerio; Lorenzini Patrizia; Trotta Maria P; Forbici Federica; Visco-Comandini Ubaldo; Gori Caterina; Narciso Pasquale; Perno Carlo F; Antinori Andrea;
Multiple drug class-wide resistance associated with poorer survival after treatment failure in a cohort of HIV-infected patients.
AIDS (London, England) 2005;19(10):1081-9.
2005: Balzarini Jan; Auwerx Joeri; Rodríguez-Barrios Fátima; Chedad Allel; Farkas Viktor; Ceccherini-Silberstein Francesca; García-Aparicio Carlos; Velázquez Sonsoles; De Clercq Erik; Perno Carlo-Federico; Camarasa María-José; Gago Federico
The amino acid Asn136 in HIV-1 reverse transcriptase (RT) maintains efficient association of both RT subunits and enables the rational design of novel RT inhibitors.
Molecular pharmacology 2005;68(1):49-60.
2005: Aquaro Stefano; Svicher Valentina; Ceccherini-Silberstein Francesca; Cenci Alessandra; Marcuccilli Fabbio; Giannella Sara; Marcon Luisa; Caliò Raffaele; Balzarini Jan; Perno Carlo-Federico
Limited development and progression of resistance of HIV-1 to the nucleoside analogue reverse transcriptase inhibitor lamivudine in human primary macrophages.
The Journal of antimicrobial chemotherapy 2005;55(6):872-8.
2005: Svicher Valentina; Ceccherini-Silberstein Francesca; Erba Fulvio; Santoro Maria; Gori Caterina; Bellocchi Maria Concetta; Giannella Sara; Trotta Maria Paola; Monforte Antonella d'Arminio; Antinori Andrea; Perno Carlo Federico
Novel human immunodeficiency virus type 1 protease mutations potentially involved in resistance to protease inhibitors.
Antimicrobial agents and chemotherapy 2005;49(5):2015-25.
2005: Auwerx Joeri; Van Nieuwenhove Joke; Rodríguez-Barrios Fátima; de Castro Sonia; Velázquez Sonsoles; Ceccherini-Silberstein Francesca; De Clercq Erik; Camarasa María-José; Perno Carlo-Federico; Gago Federico; Balzarini Jan
The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs.
FEBS letters 2005;579(11):2294-300.
2005: Palombi Leonardo; Perno Carlo Federico; Marazzi Maria Cristina
HIV/AIDS in Africa: treatment as a right and strategies for fair implementation. False assumptions on the basis of a minimalistic approach.
AIDS (London, England) 2005;19(5):536-7.
2005: Rossi Luigia; Serafini Sonja; Antonelli Antonella; Pierigé Francesca; Carnevali Andrea; Battistelli Valeria; Malatesta Manuela; Balestra Emanuela; Caliò Raffaele; Perno Carlo-Federico; Magnani Mauro
Macrophage depletion induced by clodronate-loaded erythrocytes.
Journal of drug targeting 2005;13(2):99-111.
2005: Aquaro Stefano; Ronga Luigi; Pollicita Michela; Antinori Andrea; Ranazzi Alessandro; Perno Carlo Federico
Human immunodeficiency virus infection and acquired immunodeficiency syndrome dementia complex: role of cells of monocyte-macrophage lineage.
Journal of neurovirology 2005;11 Suppl 3():58-66.
2005: Aquaro Stefano; Perno Carlo-Federico
Assessing the relative efficacy of antiretroviral activity of different drugs on macrophages.
Methods in molecular biology (Clifton, N.J.) 2005;304():445-53.
2005: Boffito Marta; Acosta Edward; Burger David; Fletcher Courtney V; Flexner Charles; Garaffo Rodolphe; Gatti Giorgio; Kurowski Michael; Perno Carlo Federico; Peytavin Gilles; Regazzi Mario; Back David
Therapeutic drug monitoring and drug-drug interactions involving antiretroviral drugs.
Antiviral therapy 2005;10(4):469-77.
2005: Boffito Marta; Acosta Edward; Burger David; Fletcher Courtney V; Flexner Charles; Garaffo Rodolphe; Gatti Giorgio; Kurowski Michael; Perno Carlo Federico; Peytavin Gilles; Regazzi Mario; Back David
Current status and future prospects of therapeutic drug monitoring and applied clinical pharmacology in antiretroviral therapy.
Antiviral therapy 2005;10(3):375-92.
2004: De Luca Andrea; Cozzi-Lepri Alessandro; Perno Carlo-Federico; Balotta Claudia; Di Giambenedetto Simona; Poggio Antonio; Pagano Gabriella; Tositti Giulia; Piscopo Rita; Del Forno Antonio; Chiodo Francesco; Magnani Giacomo; d'Arminio Monforte Antonella;
Variability in the interpretation of transmitted genotypic HIV-1 drug resistance and prediction of virological outcomes of the initial HAART by distinct systems.
Antiviral therapy 2004;9(5):743-52.
2004: Balzarini Jan; Hatse Sigrid; Vermeire Kurt; Princen Katrien; Aquaro Stefano; Perno Carlo-Federico; De Clercq Erik; Egberink Herman; Vanden Mooter Guy; Peumans Willy; Van Damme Els; Schols Dominique
Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection.
Antimicrobial agents and chemotherapy 2004;48(10):3858-70.
2004: De Luca Andrea; Vendittelli Marilena; Baldini Francesco; Di Giambenedetto Simona; Trotta Maria Paola; Cingolani Antonella; Bacarelli Alessandra; Gori Caterina; Perno Carlo Federico; Antinori Andrea; Ulivi Giovanni
Construction, training and clinical validation of an interpretation system for genotypic HIV-1 drug resistance based on fuzzy rules revised by virological outcomes.
Antiviral therapy 2004;9(4):583-93.
2004: Balzarini Jan; Aquaro Stefano; Hassan-Abdallah Alshaimaa; Daluge Susan M; Perno Carlo-Federico; McGuigan Chris
Improved antiviral activity of the aryloxymethoxyalaninyl phosphoramidate (APA) prodrug of abacavir (ABC) is due to the formation of markedly increased carbovir 5'-triphosphate metabolite levels.
FEBS letters 2004;573(1-3):38-44.
2004: Ceccherini-Silberstein Francesca; Erba Fulvio; Gago Federico; Bertoli Ada; Forbici Federica; Bellocchi Maria Concetta; Gori Caterina; D'Arrigo Roberta; Marcon Luisa; Balotta Claudia; Antinori Andrea; Monforte Antonella D'Arminio; Perno Carlo-Federico
Identification of the minimal conserved structure of HIV-1 protease in the presence and absence of drug pressure.
AIDS (London, England) 2004;18(12):F11-9.
2004: Zaccarelli Mauro; Tozzi Valerio; Perno Carlo Federico; Antinori Andrea
The challenge of antiretroviral-drug-resistant HIV: is there any possible clinical advantage?
Current HIV research 2004;2(3):283-92.
2004: Violin Michela; Velleca Rossella; Cozzi-Lepri Alessandro; Riva Chiara; Grossi Paolo Antonio; Carnevale Giuseppe; Rizzardini Giuliano; Petrelli Enzo; Perno Carlo Federico; Monforte Antonella d'Arminio; Balotta Claudia;
Prevalence of HIV-1 primary drug resistance in seroconverters of the ICoNA cohort over the period 1996-2001.
Journal of acquired immune deficiency syndromes (1999) 2004;36(2):761-4.
2004: Perno Carlo Federico; Cozzi-Lepri Alessandro; Forbici Federica; Bertoli Ada; Violin Michela; Stella Mura Maria; Cadeo Giampiero; Orani Anna; Chirianni Antonio; De Stefano Carlo; Balotta Claudia; d'Arminio Monforte Antonella;
Minor mutations in HIV protease at baseline and appearance of primary mutation 90M in patients for whom their first protease-inhibitor antiretroviral regimens failed.
The Journal of infectious diseases 2004;189(11):1983-7.
2004: Tozzi Valerio; Zaccarelli Mauro; Narciso Pasquale; Trotta Maria Paola; Ceccherini-Silberstein Francesca; De Longis Patrizio; D'Offizi Giampiero; Forbici Federica; D'Arrigo Roberta; Boumis Evangelo; Bellagamba Rita; Bonfigli Sandro; Carvelli Chiarina; Antinori Andrea; Perno Carlo Federico
Mutations in HIV-1 reverse transcriptase potentially associated with hypersusceptibility to nonnucleoside reverse-transcriptase inhibitors: effect on response to efavirenz-based therapy in an urban observational cohort.
The Journal of infectious diseases 2004;189(9):1688-95.
2004: Santoro M; Ceccherini-Silberstein F; Gori C; Svicher V; Forbici F; Bellocchi M C; d'Arrigo R; Bertoli A; Giannella S; Trotta M P; Bonfigli S; Antinori A; Perno C F
Temporal change in the use of genotypic resistance testing over the years 1999--2003.
The new microbiologica : official journal of the Italian Society for Medical, Odontoiatric, and Clinical Microbiology (SIMMOC) 2004;27(2 Suppl 1):141-4.
2004: Liotta Giuseppe; Perno Carlo F; Ceffa Susanna; Gialloreti Leonardo Emberti; Coehlo Elisabeth; Erba Fulvio; Guidotti Giovanni; Marazzi Maria Cristina; Narciso Pasquale; Palombi Leonardo
Is total lymphocyte count a reliable predictor of the CD4 lymphocyte cell count in resource-limited settings?
AIDS (London, England) 2004;18(7):1082-3.
2004: Savarino Andrea; Lucia Mothanje B; Rastrelli Elena; Rutella Sergio; Golotta Caterina; Morra Emanuella; Tamburrini Enrica; Perno Carlo Federico; Boelaert Johan R; Sperber Kirk; Cauda Roberto
Anti-HIV effects of chloroquine: inhibition of viral particle glycosylation and synergism with protease inhibitors.
Journal of acquired immune deficiency syndromes (1999) 2004;35(3):223-32.
2004: Zaccarelli Mauro; Perno Carlo Federico; Forbici Federica; Soldani Fabio; Bonfigli Sandro; Gori Caterina; Trotta Maria Paola; Bellocchi Maria Concetta; Liuzzi Giuseppina; D'Arrigo Roberta; De Longis Patrizio; Boumis Evangelo; Bellagamba Rita; Tozzi Valerio; Narciso Pasquale; Antinori Andrea
Q151M-mediated multinucleoside resistance: prevalence, risk factors, and response to salvage therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;38(3):433-7.
2004: Aquaro Stefano; Guenci Tania; Di Santo Fabiola; Francesconi Mauro; Caliò Raffaele; Perno Carlo Federico
Potent antiviral activity of amprenavir in primary macrophages infected by human immunodeficiency virus.
Antiviral research 2004;61(2):133-7.
2004: Violin Michela; Cozzi-Lepri Alessandro; Velleca Rossella; Vincenti Antonella; D'Elia Salvatore; Chiodo Francesco; Ghinelli Florio; Bertoli Ada; d'Arminio Monforte Antonella; Perno Carlo Federico; Moroni Mauro; Balotta Claudia
Risk of failure in patients with 215 HIV-1 revertants starting their first thymidine analog-containing highly active antiretroviral therapy.
AIDS (London, England) 2004;18(2):227-35.
2004: Perno C-F; Balestra E; Francesconi M; Abdelahad D; Caliò R; Balzarini J; Aquaro S
Antiviral profile of HIV inhibitors in macrophages: implications for therapy.
Current topics in medicinal chemistry 2004;4(9):1009-15.
2003: Ciancio Bruno Christian; Trotta Maria Paola; Lorenzini Patrizia; Forbici Federica; Visco-Comandini Ubaldo; Gori Caterina; Bonfigli Sandro; Bellocchi Maria Concetta; Sette Pietro; D'Arrigo Roberta; Tozzi Valerio; Zaccarelli Mauro; Boumis Evangelo; Narciso Pasquale; Perno Carlo Federico; Antinori Andrea
The effect of number of mutations and of drug-class sparing on virological response to salvage genotype-guided antiretroviral therapy.
Antiviral therapy 2003;8(6):611-6.
2003: Giancola Maria Letizia; Uccella Ilaria; Alba Lucia; Lorenzini Patrizia; Soldani Fabio; Capobianchi Maria; Ruco Luigi; Perno Carlo Federico; Antinori Andrea
HIV Type 1 replication in cerebrospinal fluid of patients with AIDS-related non-Hodgkin's lymphoma receiving chemotherapy and antiretroviral therapy.
AIDS research and human retroviruses 2003;19(12):1091-5.
2003: De Luca Andrea; Perno Carlo-Federico
Impact of different HIV resistance interpretation by distinct systems on clinical utility of resistance testing.
Current opinion in infectious diseases 2003;16(6):573-80.
2003: Magnani Mauro; Balestra Emanuela; Fraternale Alessandra; Aquaro Stefano; Paiardini Mirko; Cervasi Barbara; Casabianca Anna; Garaci Enrico; Perno Carlo-Federico
Drug-loaded red blood cell-mediated clearance of HIV-1 macrophage reservoir by selective inhibition of STAT1 expression.
Journal of leukocyte biology 2003;74(5):764-71.
2003: Collman Ronald G; Perno Carlo-Federico; Crowe Suzanne M; Stevenson Mario; Montaner Luis J
HIV and cells of macrophage/dendritic lineage and other non-T cell reservoirs: new answers yield new questions.
Journal of leukocyte biology 2003;74(5):631-4.
2003: Garaci Enrico; Aquaro Stefano; Lapenta Caterina; Amendola Alessandra; Spada Massimo; Covaceuszach Sonia; Perno Carlo-Federico; Belardelli Filippo
Anti-nerve growth factor Ab abrogates macrophage-mediated HIV-1 infection and depletion of CD4+ T lymphocytes in hu-SCID mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):8927-32.
2003: De Luca Andrea; Cingolani Antonella; Di Giambenedetto Simona; Trotta Maria Paola; Baldini Francesco; Rizzo Maria Gabriella; Bertoli Ada; Liuzzi Giuseppina; Narciso Pasquale; Murri Rita; Ammassari Adriana; Perno Carlo Federico; Antinori Andrea
Variable prediction of antiretroviral treatment outcome by different systems for interpreting genotypic human immunodeficiency virus type 1 drug resistance.
The Journal of infectious diseases 2003;187(12):1934-43.
2003: Liuzzi Giuseppina; D'Offizi Gianpiero; Topino Simone; Zaccarelli Mauro; Amendola Alessandra; Capobianchi Maria Rosaria; Perno Carlo Federico; Narciso Pasquale; Antinori Andrea
Dynamics of viral load rebound in plasma and semen after stopping effective antiretroviral therapy.
AIDS (London, England) 2003;17(7):1089-92.
2003: Balestra E; Aquaro S; Perno C F
HIV/HCV co-infection: the magnitude of the problem.
Journal of biological regulators and homeostatic agents 2003;17(2):138-43.
2003: Zaccarelli Mauro; Perno Carlo Federico; Forbici Federica; Cingolani Antonella; Liuzzi Guiseppina; Bertoli Ada; Trotta Maria Paola; Bellocchi Maria Concetta; Di Giambenedetto Simona; Tozzi Valerio; Gori Caterina; D'Arrigo Roberta; De Longis Patrizio; Noto Pasquale; Girardi Enrico; De Luca Andrea; Antinori Andrea
Using a database of HIV patients undergoing genotypic resistance test after HAART failure to understand the dynamics of M184V mutation.
Antiviral therapy 2003;8(1):51-6.
2003: Antinori Andrea; Cingolani Antonella; Giancola Maria Letizia; Forbici Federica; De Luca Andrea; Perno Carlo Federico
Clinical implications of HIV-1 drug resistance in the neurological compartment.
Scandinavian journal of infectious diseases. Supplementum 2003;106():41-4.
2003: Perno Carlo Federico; Cenci Alessandra; Piro Cristina; D'Arrigo Roberta; Marcon Luisa; Ceccherini-Silberstein Francesca; Ascoli Marchetti Franca; Caliò Raffaele; Antinori Andrea
HIV fitness and resistance as covariates associated with the appearance of mutations under antiretroviral treatment.
Scandinavian journal of infectious diseases. Supplementum 2003;106():37-40.
2003: De Luca Andrea; Antinori Andrea; Di Giambenedetto Simona; Cingolani Antonella; Colafigli Manuela; Perno Carlo Federico; Cauda Roberto
Interpretation systems for genotypic drug resistance of HIV-1.
Scandinavian journal of infectious diseases. Supplementum 2003;106():29-34.
2002: Perno Carlo Federico; Ceccherini-Silberstein Francesca; De Luca Andrea; Cozzi-Lepri Alessandro; Gori Caterina; Cingolani Antonella; Bellocchi Maria Concetta; Trotta Maria Paola; Piano Paola; Forbici Federica; Scasso Antonio; Vullo Vincenzo; d'Arminio Monforte Antonella; Antinori Andrea;
Virologic correlates of adherence to antiretroviral medications and therapeutic failure.
Journal of acquired immune deficiency syndromes (1999) 2002;31 Suppl 3():S118-22.
2002: Aquaro Stefano; Bagnarelli Patrizia; Guenci Tania; De Luca Andrea; Clementi Massimo; Balestra Emanuela; Caliò Raffaele; Perno Carlo-Federico
Long-term survival and virus production in human primary macrophages infected by human immunodeficiency virus.
Journal of medical virology 2002;68(4):479-88.
2002: Antinori Andrea; Giancola Maria Letizia; Grisetti Susanna; Soldani Fabio; Alba Lucia; Liuzzi Giuseppina; Amendola Alessandra; Capobianchi Maria; Tozzi Valerio; Perno Carlo Federico
Factors influencing virological response to antiretroviral drugs in cerebrospinal fluid of advanced HIV-1-infected patients.
AIDS (London, England) 2002;16(14):1867-76.
2002: Muscoli Carolina; Salvemini Daniela; Paolino Donatella; Iannone Michelangelo; Palma Ernesto; Cufari Antonio; Rotiroti Domenicantonio; Perno Carlo Federico; Aquaro Stefano; Mollace Vincenzo
Peroxynitrite decomposition catalyst prevents apoptotic cell death in a human astrocytoma cell line incubated with supernatants of HIV-infected macrophages.
BMC neuroscience 2002;3():13.
2002: Antinori Andrea; Zaccarelli Mauro; Cingolani Antonella; Forbici Federica; Rizzo Maria G; Trotta Maria P; Di Giambenedetto Simona; Narciso Pasquale; Ammassari Adriana; Girardi Enrico; De Luca Andrea; Perno Carlo F
Cross-resistance among nonnucleoside reverse transcriptase inhibitors limits recycling efavirenz after nevirapine failure.
AIDS research and human retroviruses 2002;18(12):835-8.
2002: Aquaro Stefano; Caliò Raffaele; Balzarini Jan; Bellocchi Maria Concetta; Garaci Enrico; Perno Carlo Federico
Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir.
Antiviral research 2002;55(2):209-25.
2002: Mussini Cristina; Bugarini Roberto; Perno Carlo Federico; Antinori Andrea; Borghi Vanni; Bertoli Ada; D'Arrigo Roberta; Bedini Andrea; Mongiardo Nicola; Cossarizza Andrea; Esposito Roberto
Kinetics of CD4 cells after discontinuation of antiretroviral therapy in patients with virological failure and a CD4 cell count greater than 500 cells/microl.
AIDS (London, England) 2002;16(11):1551-4.
2002: Balzarini J; Pannecouque C; De Clercq E; Aquaro S; Perno C-F; Egberink H; Holý A
Antiretrovirus activity of a novel class of acyclic pyrimidine nucleoside phosphonates.
Antimicrobial agents and chemotherapy 2002;46(7):2185-93.
2002: Back David; Gatti Giorgio; Fletcher Courtney; Garaffo Rodolphe; Haubrich Richard; Hoetelmans Richard; Kurowski Michael; Luber Andrew; Merry Concepta; Perno Carlo-Federico
Therapeutic drug monitoring in HIV infection: current status and future directions.
AIDS (London, England) 2002;16 Suppl 1():S5-37.
2002: Perno Carlo Federico; Cozzi-Lepri Alessandro; Balotta Claudia; Bertoli Ada; Violin Michela; Monno Laura; Zauli Tiziano; Montroni Maria; Ippolito Giuseppe; d'Arminio-Monforte Antonella;
Low prevalence of primary mutations associated with drug resistance in antiviral-naive patients at therapy initiation.
AIDS (London, England) 2002;16(4):619-24.
2002: Zaccarelli M; Barracchini A; De Longis P; Perno C F; Soldani F; Liuzzi G; Serraino D; Ippolito G; Antinori A
Factors related to virologic failure among HIV-positive injecting drug users treated with combination antiretroviral therapy including two nucleoside reverse transcriptase inhibitors and nevirapine.
AIDS patient care and STDs 2002;16(2):67-73.
2002: Violin M; Forbici F; Cozzi-Lepri A; Velleca R; Bertoli A; Riva C; Giannella S; Manconi P E; Lazzarin A; Pasquinucci S; Tacconi L; Carnevale G; Mazzotta F; Bonazzi L; Montroni M; Chirianni A; Capobianchi M; Ippolito G; Moroni M; Perno C F; D'Arminio-Monforte A;
Primary HIV-1 resistance in recently and chronically infected individuals of the Italian Cohort Naive for Antiretrovirals.
Journal of biological regulators and homeostatic agents 2002;16(1):37-43.
2002: Mollace Vincenzo; Salvemini Daniela; Riley Dennis P; Muscoli Carolina; Iannone Michelangelo; Granato Teresa; Masuelli Laura; Modesti Andrea; Rotiroti Domenicantonio; Nisticó Robert; Bertoli Ada; Perno Carlo-Federico; Aquaro Stefano
The contribution of oxidative stress in apoptosis of human-cultured astroglial cells induced by supernatants of HIV-1-infected macrophages.
Journal of leukocyte biology 2002;71(1):65-72.
2001: Antinori A; Liuzzi G; Cingolani A; Bertoli A; Di Giambenedetto S; Trotta M P; Rizzo M G; Girardi E; De Luca A; Perno C F
Drug-resistant mutants of HIV-1 in patients exhibiting increasing CD4 cell count despite virological failure of highly active antiretroviral therapy.
AIDS (London, England) 2001;15(17):2325-7.
2001: Perno C F; Cozzi-Lepri A; Balotta C; Forbici F; Violin M; Bertoli A; Facchi G; Pezzotti P; Cadeo G; Tositti G; Pasquinucci S; Pauluzzi S; Scalzini A; Salassa B; Vincenti A; Phillips A N; Dianzani F; Appice A; Angarano G; Monno L; Ippolito G; Moroni M; d' Arminio Monforte A;
Secondary mutations in the protease region of human immunodeficiency virus and virologic failure in drug-naive patients treated with protease inhibitor-based therapy.
The Journal of infectious diseases 2001;184(8):983-91.
2001: Perno C F; Cozzi-Lepri A; Balotta C; Forbici F; Violin M; Bertoli A; Facchi G; Pezzotti P; Angarano G; Arici C; Narciso P; Orani A; Raise E; Scalzini A; Poggio A; Ippolito G; Moroni M; Monforte A D;
Impact of mutations conferring reduced susceptibility to lamivudine on the response to antiretroviral therapy.
Antiviral therapy 2001;6(3):195-8.
2001: Brand G; Schiavano G F; Balestra E; Tavazzi B; Perno C F; Magnani M
The potency of acyclovir can be markedly different in different cell types.
Life sciences 2001;69(11):1285-90.
2001: Balotta C; Facchi G; Violin M; Van Dooren S; Cozzi-Lepri A; Forbici F; Bertoli A; Riva C; Senese D; Caramello P; Carnevale G; Rizzardini G; Cremonini L; Monno L; Rezza G; Perno C F; Ippolito G; d'Arminio-Monforte A; Vandamme A M; Moroni M;
Increasing prevalence of non-clade B HIV-1 strains in heterosexual men and women, as monitored by analysis of reverse transcriptase and protease sequences.
Journal of acquired immune deficiency syndromes (1999) 2001;27(5):499-505.
2001: Balestra E; Perno C F; Aquaro S; Panti S; Bertoli A; Piacentini M; Forbici F; D'Arrigo R; Calió R; Garaci E
Macrophages: a crucial reservoir for human immunodeficiency virus in the body.
Journal of biological regulators and homeostatic agents 2001;15(3):272-6.
2001: Mollace V; Nottet H S; Clayette P; Turco M C; Muscoli C; Salvemini D; Perno C F
Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidants.
Trends in neurosciences 2001;24(7):411-6.
2001: Balzarini J; Camarasa M J; Pérez-Pérez M J; San-Félix A; Velázquez S; Perno C F; De Clercq E; Anderson J N; Karlsson A
Exploitation of the low fidelity of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and the nucleotide composition bias in the HIV-1 genome to alter the drug resistance development of HIV.
Journal of virology 2001;75(13):5772-7.
2001: Rossi L; Serafini S; Cappellacci L; Balestra E; Brandi G; Schiavano G F; Franchetti P; Grifantini M; Perno C F; Magnani M
Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus.
The Journal of antimicrobial chemotherapy 2001;47(6):819-27.
2001: Franchetti P; Rossi L; Cappellacci L; Pasqualini M; Grifantini M; Balestra E; Forbici F; Perno C F; Serafini S; Magnani M
Inhibition of HIV-1 replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine and 9-(R)-2-(phosphono methoxypropyl)adenine.
Antiviral chemistry & chemotherapy 2001;12(3):151-9.
2000: Balzarini J; Aquaro S; Knispel T; Rampazzo C; Bianchi V; Perno C F; De Clercq E; Meier C
Cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP.
Molecular pharmacology 2000;58(5):928-35.
2000: Aquaro S; Panti S; Caroleo M C; Balestra E; Cenci A; Forbici F; Ippolito G; Mastino A; Testi R; Mollace V; Caliò R; Perno C F
Primary macrophages infected by human immunodeficiency virus trigger CD95-mediated apoptosis of uninfected astrocytes.
Journal of leukocyte biology 2000;68(3):429-35.
2000: Franchetti P; Abu Sheikha G; Cappellacci L; Marchetti S; Grifantini M; Balestra E; Perno C; Benatti U; Brandi G; Rossi L; Magnani M
A new acyclic heterodinucleotide active against human immunodeficiency virus and herpes simplex virus.
Antiviral research 2000;47(3):149-58.
2000: Van Laethem K; Schmit J C; Pelemans H; Balzarini J; Witvrouw M; Pérez-Pérez M J; Camarasa M J; Esnouf R M; Aquaro S; Cenci A; Perno C F; Hermans P; Sprecher S; Ruiz L; Clotet B; Van Wijngaerden E; Van Ranst M; Desmyter J; De Clercq E; Vandamme A M
Presence of 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1",2"-oxath iole-2",2"-dioxide) (TSAO)-resistant virus strains in TSAO-inexperienced HIV patients.
AIDS research and human retroviruses 2000;16(9):825-33.
2000: Cenci A; Bertoli A; Tambussi G; Menzo S; Clementi M; Lazzarin A; Capiluppi B; Ciuffreda D; Forbici F; Aquaro S; Marcuccilli F; Caliò R; Perno C F
Viral dynamics and mutations in the pol gene during primary HIV-1 infection.
Journal of biological regulators and homeostatic agents 2000;14(1):7-10.
2000: Aquaro S; Wedgwood O; Yarnold C; Cahard D; Pathinara R; McGuigan C; Calio' R; de Clercq E; Balzarini J; Perno C F
Activities of masked 2',3'-dideoxynucleoside monophosphate derivatives against human immunodeficiency virus in resting macrophages.
Antimicrobial agents and chemotherapy 2000;44(1):173-7.
1999: Balzarini J; Naesens L; Aquaro S; Knispel T; Perno C; De Clercq E; Meier C
Intracellular metabolism of CycloSaligenyl 3'-azido-2', 3'-dideoxythymidine monophosphate, a prodrug of 3'-azido-2', 3'-dideoxythymidine (zidovudine).
Molecular pharmacology 1999;56(6):1354-61.
1999: Garaci E; Caroleo M C; Aloe L; Aquaro S; Piacentini M; Costa N; Amendola A; Micera A; Caliò R; Perno C F; Levi-Montalcini R
Nerve growth factor is an autocrine factor essential for the survival of macrophages infected with HIV.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):14013-8.
1999: Franchetti P; Abu Sheikha G; Cappellacci L; Grifantini M; Balestra E; Perno C F; Brandi G; Rossi L; Magnani M
Synthesis and biological application of a new heterodinucleotide with both anti-HSV and anti-HIV activity.
Nucleosides & nucleotides 1999;18(4-5):989-90.
1998: Perno C F
12th World Conference on AIDS. Geneva, Switzerland, 28 June-3 July 1998]
La Clinica terapeutica 1998;149(5):329-30.
1998: Perno C F; Newcomb F M; Davis D A; Aquaro S; Humphrey R W; Caliò R; Yarchoan R
Relative potency of protease inhibitors in monocytes/macrophages acutely and chronically infected with human immunodeficiency virus.
The Journal of infectious diseases 1998;178(2):413-22.
1998: Rossi L; Brandi G; Schiavano G F; Balestra E; Millo E; Scarfi S; Damonte G; Gasparini A; Magnani M; Perno C F; Benatti U; De Flora A
Macrophage protection against human immunodeficiency virus or herpes simplex virus by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine and acyclovir.
AIDS research and human retroviruses 1998;14(5):435-44.
1998: Aquaro S; Balestra E; Panti S; Cenci A; Serra F; Francesconi M; Abdelahad D; Caliò R; Perno C F
[Correlation between HIV-inhibiting drug activity in human macrophages and clinical outcome]
La Clinica terapeutica 1998;149(921):37-41.
1998: Perno C F
[Fifth Conference on Retrovirus and Opportunistic infections. 1-5 February 1998, Chicago, USA]
La Clinica terapeutica 1998;149(921):11-3.
1998: Aquaro S; Caliò R; Balestra E; Bagnarelli P; Cenci A; Bertoli A; Tavazzi B; Di Pierro D; Francesconi M; Abdelahad D; Perno C F
Clinical implications of HIV dynamics and drug resistance in macrophages.
Journal of biological regulators and homeostatic agents 1998;12(1-2 Suppl):23-7.
1997: Daelemans D; Esté J A; Witvrouw M; Pannecouque C; Jonckheere H; Aquaro S; Perno C F; De Clercq E; Vandamme A M
S-adenosylhomocysteine hydrolase inhibitors interfere with the replication of human immunodeficiency virus type 1 through inhibition of the LTR transactivation.
Molecular pharmacology 1997;52(6):1157-63.
1997: Aquaro S; Perno C F; Balestra E; Balzarini J; Cenci A; Francesconi M; Panti S; Serra F; Villani N; Caliò R
Inhibition of replication of HIV in primary monocyte/macrophages by different antiviral drugs and comparative efficacy in lymphocytes.
Journal of leukocyte biology 1997;62(1):138-43.
1997: Perno C F; Crowe S M; Kornbluth R S
A continuing enigma: the role of cells of macrophage lineage in the development of HIV disease.
Journal of leukocyte biology 1997;62(1):1-3.
1997: Balzarini J; Kruining J; Wedgwood O; Pannecouque C; Aquaro S; Perno C F; Naesens L; Witvrouw M; Heijtink R; De Clercq E; McGuigan C
Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus.
FEBS letters 1997;410(2-3):324-8.
1997: Cenci A; Perno C F; Menzo S; Clementi M; Erba F; Tavazzi B; Di Pierro D; Aquaro S; Caliò R
Selected nucleotide sequence of the pol gene of the monocytotropic strain HIV type 1 BaL.
AIDS research and human retroviruses 1997;13(7):629-32.
1997: Perno C F; Santoro N; Balestra E; Aquaro S; Cenci A; Lazzarino G; Di Pierro D; Tavazzi B; Balzarini J; Garaci E; Grimaldi S; Caliò R
Red blood cells mediated delivery of 9-(2-phosphonylmethoxyethyl)adenine to primary macrophages: efficiency metabolism and activity against human immunodeficiency virus or herpes simplex virus.
Antiviral research 1997;33(3):153-64.
1997: Aquaro S; Balestra E; Cenci A; Francesconi M; Caliò R; Perno C F
HIV infection in macrophage: role of long-lived cells and related therapeutical strategies.
Journal of biological regulators and homeostatic agents 1997;11(1-2):69-73.
1996: Palamara A T; Perno C F; Aquaro S; Buè M C; Dini L; Garaci E
Glutathione inhibits HIV replication by acting at late stages of the virus life cycle.
AIDS research and human retroviruses 1996;12(16):1537-41.
1996: Balzarini J; Pelemans H; Aquaro S; Perno C F; Witvrouw M; Schols D; De Clercq E; Karlsson A
Highly favorable antiviral activity and resistance profile of the novel thiocarboxanilide pentenyloxy ether derivatives UC-781 and UC-82 as inhibitors of human immunodeficiency virus type 1 replication.
Molecular pharmacology 1996;50(2):394-401.
1996: Perno C F; Balestra E; Aquaro S; Panti S; Cenci A; Lazzarino G; Tavazzi B; Di Pierro D; Balzarini J; Calio R
Potent inhibition of human immunodeficiency virus and herpes simplex virus type 1 by 9-(2-phosphonylmethoxyethyl)adenine in primary macrophages is determined by drug metabolism, nucleotide pools, and cytokines.
Molecular pharmacology 1996;50(2):359-66.
1996: Balzarini J; Karlsson A; Aquaro S; Perno C F; Cahard D; Naesens L; De Clercq E; McGuigan C
Mechanism of anti-HIV action of masked alaninyl d4T-MP derivatives.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):7295-9.
1996: Balzarini J; Aquaro S; Perno C F; Witvrouw M; Holý A; De Clercq E
Activity of the (R)-enantiomers of 9-(2-phosphonylmethoxypropyl)-adenine and 9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine against human immunodeficiency virus in different human cell systems.
Biochemical and biophysical research communications 1996;219(2):337-41.
1995: Di Pierro D; Tavazzi B; Perno C F; Bartolini M; Balestra E; Caliò R; Giardina B; Lazzarino G
An ion-pairing high-performance liquid chromatographic method for the direct simultaneous determination of nucleotides, deoxynucleotides, nicotinic coenzymes, oxypurines, nucleosides, and bases in perchloric acid cell extracts.
Analytical biochemistry 1995;231(2):407-12.
1995: Palamara A T; Perno C F; Ciriolo M R; Dini L; Balestra E; D'Agostini C; Di Francesco P; Favalli C; Rotilio G; Garaci E
Evidence for antiviral activity of glutathione: in vitro inhibition of herpes simplex virus type 1 replication.
Antiviral research 1995;27(3):237-53.
1994: Alvarez R; Velázquez S; San-Félix A; Aquaro S; De Clercq E; Perno C F; Karlsson A; Balzarini J; Camarasa M J
1,2,3-Triazole-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D- ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"-oxathiole 2",2"-dioxide) (TSAO) analogues: synthesis and anti-HIV-1 activity.
Journal of medicinal chemistry 1994;37(24):4185-94.
1994: Bergamini A; Perno C F; Dini L; Capozzi M; Pesce C D; Ventura L; Cappannoli L; Falasca L; Milanese G; Caliò R
Macrophage colony-stimulating factor enhances the susceptibility of macrophages to infection by human immunodeficiency virus and reduces the activity of compounds that inhibit virus binding.
Blood 1994;84(10):3405-12.
1994: Villani N; Caliò R; Balestra E; Balzarini J; De Clercq E; Fabrizi E; Perno C F; Del Gobbo V
9-(2-Phosphonylmethoxyethyl) adenine increases the survival of influenza virus-infected mice by an enhancement of the immune system.
Antiviral research 1994;25(2):81-9.
1994: Perno C F; Aquaro S; Rosenwirth B; Balestra E; Peichl P; Billich A; Villani N; Caliò R
In vitro activity of inhibitors of late stages of the replication of HIV in chronically infected macrophages.
Journal of leukocyte biology 1994;56(3):381-6.
1994: Caliò R; Villani N; Balestra E; Sesa F; Holy A; Balzarini J; De Clercq E; Perno C F; Del Gobbo V
Enhancement of natural killer activity and interferon induction by different acyclic nucleoside phosphonates.
Antiviral research 1994;23(1):77-89.
1993: Perno C F; Bergamini A; Pesce C D; Milanese G; Capozzi M; Aquaro S; Thaisrivongs S; Tarpley W G; Zon G; D'Agostini C
Inhibition of the protease of human immunodeficiency virus blocks replication and infectivity of the virus in chronically infected macrophages.
The Journal of infectious diseases 1993;168(5):1148-56.
1993: Hao Z; Stowe E E; Ahluwalia G; Baker D C; Hebbler A K; Chisena C; Musser S M; Kelley J A; Perno C F; Johns D G
Characterization of 2',3'-dideoxycytidine diphosphocholine and 2',3'-dideoxycytidine diphosphoethanolamine. Prominent phosphodiester metabolites of the anti-HIV nucleoside 2',3'-dideoxycytidine.
Drug metabolism and disposition: the biological fate of chemicals 1993;21(4):738-44.
1992: Bergamini A; Perno C F; Capozzi M; Mannella E; Salanitro A; Caliò R; Rocchi G
A tetrazolium-based colorimetric assay for quantification of HIV-1-induced cytopathogenicity in monocyte-macrophages exposed to macrophage-colony-stimulating factor.
Journal of virological methods 1992;40(3):275-86.
1992: Perno C F; Cooney D A; Gao W Y; Hao Z; Johns D G; Foli A; Hartman N R; Caliò R; Broder S; Yarchoan R
Effects of bone marrow stimulatory cytokines on human immunodeficiency virus replication and the antiviral activity of dideoxynucleosides in cultures of monocyte/macrophages.
Blood 1992;80(4):995-1003.
1992: Bergamini A; Perno C F; Balzarini J; Capozzi M; Marinelli L; Milanese G; Pesce C D; Calió R; Rocchi G
Selective inhibition of HIV replication by adriamycin in macrophages but not in lymphocytes.
AIDS research and human retroviruses 1992;8(7):1239-47.
1992: Balzarini J; Pérez-Pérez M J; San-Félix A; Schols D; Perno C F; Vandamme A M; Camarasa M J; De Clercq E
2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4392-6.
1992: Perno C F; Yarchoan R; Balzarini J; Bergamini A; Milanese G; Pauwels R; De Clercq E; Rocchi G; Calio R
Different pattern of activity of inhibitors of the human immunodeficiency virus in lymphocytes and monocyte/macrophages.
Antiviral research 1992;17(4):289-304.
1992: Perno C F; Caliò R
[New therapeutic trends in AIDS]
La Clinica terapeutica 1992;140(2):197-204.
1991: Yarchoan R; Pluda J M; Perno C F; Mitsuya H; Broder S
Anti-retroviral therapy of human immunodeficiency virus infection: current strategies and challenges for the future.
Blood 1991;78(4):859-84.
1991: Balzarini J; Perno C F; Schols D; De Clercq E
Activity of acyclic nucleoside phosphonate analogues against human immunodeficiency virus in monocyte/macrophages and peripheral blood lymphocytes.
Biochemical and biophysical research communications 1991;178(1):329-35.
1991: Del Gobbo V; Foli A; Balzarini J; De Clercq E; Balestra E; Villani N; Marini S; Perno C F; Calio R
Immunomodulatory activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA), a potent anti-HIV nucleotide analogue, on in vivo murine models.
Antiviral research 1991;16(1):65-75.
1990: Perno C F; Cooney D A; Currens M J; Rocchi G; Johns D G; Broder S; Yarchoan R
Ability of anti-HIV agents to inhibit HIV replication in monocyte/macrophages or U937 monocytoid cells under conditions of enhancement by GM-CSF or anti-HIV antibody.
AIDS research and human retroviruses 1990;6(8):1051-5.
1990: Yarchoan R; Mitsuya H; Pluda J M; Marczyk K S; Thomas R V; Hartman N R; Brouwers P; Perno C F; Allain J P; Johns D G
The National Cancer Institute phase I study of 2',3'-dideoxyinosine administration in adults with AIDS or AIDS-related complex: analysis of activity and toxicity profiles.
Reviews of infectious diseases 1990;12 Suppl 5():S522-33.
1990: Perno C F; Baseler M W; Broder S; Yarchoan R
Infection of monocytes by human immunodeficiency virus type 1 blocked by inhibitors of CD4-gp120 binding, even in the presence of enhancing antibodies.
The Journal of experimental medicine 1990;171(4):1043-56.
1990: Masood R; Ahluwalia G S; Cooney D A; Fridland A; Marquez V E; Driscoll J S; Hao Z; Mitsuya H; Perno C F; Broder S
2'-Fluoro-2',3'-dideoxyarabinosyladenine: a metabolically stable analogue of the antiretroviral agent 2',3'-dideoxyadenosine.
Molecular pharmacology 1990;37(4):590-6.
1990: Hao Z; Cooney D A; Farquhar D; Perno C F; Zhang K; Masood R; Wilson Y; Hartman N R; Balzarini J; Johns D G
Potent DNA chain termination activity and selective inhibition of human immunodeficiency virus reverse transcriptase by 2',3'-dideoxyuridine-5'-triphosphate.
Molecular pharmacology 1990;37(2):157-63.
1990: Bergamini A; Ercoli L; Perno C F
[Inhibition of alfa interferon and ampligen of human immunodeficiency virus (HIV) replication in monocyte-macrophage subpopulations]
Medicina (Florence, Italy) 1990;10(1):34-6.
1990: Ercoli L; Perno C F; Bergamini A; Rocchi G
[The monocyte-macrophage system and acquired immunodeficiency syndrome (AIDS)]
Medicina (Florence, Italy) 1990;10(1):1-8.
1990: Yarchoan R; Pluda J M; Perno C F; Mitsuya H; Thomas R V; Wyvill K M; Broder S
Initial clinical experience with dideoxynucleosides as single agents and in combination therapy.
Annals of the New York Academy of Sciences 1990;616():328-43.
1989: Baba M; Tanaka H; De Clercq E; Pauwels R; Balzarini J; Schols D; Nakashima H; Perno C F; Walker R T; Miyasaka T
Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative.
Biochemical and biophysical research communications 1989;165(3):1375-81.
1989: Yarchoan R; Mitsuya H; Thomas R V; Pluda J M; Hartman N R; Perno C F; Marczyk K S; Allain J P; Johns D G; Broder S
In vivo activity against HIV and favorable toxicity profile of 2',3'-dideoxyinosine.
Science (New York, N.Y.) 1989;245(4916):412-5.
1989: Perno C F; Yarchoan R; Cooney D A; Hartman N R; Webb D S; Hao Z; Mitsuya H; Johns D G; Broder S
Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine.
The Journal of experimental medicine 1989;169(3):933-51.
1988: Hao Z; Cooney D A; Hartman N R; Perno C F; Fridland A; DeVico A L; Sarngadharan M G; Broder S; Johns D G
Factors determining the activity of 2',3'-dideoxynucleosides in suppressing human immunodeficiency virus in vitro.
Molecular pharmacology 1988;34(4):431-5.
1988: Perno C F; Yarchoan R; Cooney D A; Hartman N R; Gartner S; Popovic M; Hao Z; Gerrard T L; Wilson Y A; Johns D G
Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides.
The Journal of experimental medicine 1988;168(3):1111-25.
1988: D'Onofrio C; Perno C F; Mazzetti P; Graziani G; Calio' R; Bonmassar E
Depression of early phase of HTLV-I infection in vitro mediated by human beta-interferon.
British journal of cancer 1988;57(5):481-8.
1988: Yarchoan R; Perno C F; Thomas R V; Klecker R W; Allain J P; Wills R J; McAtee N; Fischl M A; Dubinsky R; McNeely M C
Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT).
Lancet 1988;1(8577):76-81.
1988: Yarchoan R; Thomas R V; Grafman J; Wichman A; Dalakas M; McAtee N; Berg G; Fischl M; Perno C F; Klecker R W
Long-term administration of 3'-azido-2',3'-dideoxythymidine to patients with AIDS-related neurological disease.
Annals of neurology 1988;23 Suppl():S82-7.
1987: Pesce C D; Ciprani F; D'Onofrio C; Alvino E; Perno C F; Bonmassar E; Caliò R
Low concentrations of suramin can reduce in vitro infection of human cord blood lymphocytes with HTLV-I during long-term culture.
Antiviral research 1987;8(5-6):247-60.

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