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Mauro Perretti
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71
Flower, Roderick
23
Getting, Stephen
16
Parente, Luca
15
Solito, Egle
15
Oliani, Sonia
11
Gavins, Felicity
11
Paul-Clark, Mark
11
Yona, Simon
9
Wheller, Samantha
7
La, Mylinh
6
Goulding, Nicolas
6
D'Acquisto, Fulvio
6
Damazo, Amilcar Sabino
6
Das, AM
6
Ajuebor, MN
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All Publications
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2009: Duchene Johan; Cayla Cécile; Vessillier Sandrine; Scotland Ramona; Yamashiro Kazuo; Lecomte Florence; Syed Irfan; Vo Phuong; Marrelli Alessandra; Pitzalis Costantino; Cipollone Francesco; Schanstra Joost; Bascands Jean-Loup; Hobbs Adrian J; Perretti Mauro; Ahluwalia Amrita
Laminar shear stress regulates endothelial kinin B1 receptor expression and function: potential implication in atherogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(11):1757-63.
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2009: Perretti Mauro; Dalli Jesmond
Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics.
British journal of pharmacology 2009;158(4):936-46.
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2009: Norling Lucy V; Perretti Mauro; Cooper Dianne
Endogenous galectins and the control of the host inflammatory response.
The Journal of endocrinology 2009;201(2):169-84.
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2009: Huggins Anthony; Paschalidis Nikolaos; Flower Roderick J; Perretti Mauro; D'Acquisto Fulvio
Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(4):985-96.
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2009: Tripatara Pinpat; Patel Nimesh S A; Brancaleone Vincenzo; Renshaw Derek; Rocha Joao; Sepodes Bruno; Mota-Filipe Helder; Perretti Mauro; Thiemermann Christoph
Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study.
European journal of pharmacology 2009;606(1-3):205-9.
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2009: Maione Francesco; Paschalidis Nikolaos; Mascolo Nicola; Dufton Neil; Perretti Mauro; D'Acquisto Fulvio
Interleukin 17 sustains rather than induces inflammation.
Biochemical pharmacology 2009;77(5):878-87.
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2009: Gastardelo Thaís Santana; Damazo Amílcar Sabino; Dalli Jesmond; Flower Roderick J; Perretti Mauro; Oliani Sonia Maria
Functional and ultrastructural analysis of annexin A1 and its receptor in extravasating neutrophils during acute inflammation.
The American journal of pathology 2009;174(1):177-83.
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2008: Getting Stephen J; Riffo-Vasquez Yanira; Pitchford Simon; Kaneva Magdalena; Grieco Paolo; Page Clive P; Perretti Mauro; Spina Domenico
A role for MC3R in modulating lung inflammation.
Pulmonary pharmacology & therapeutics 2008;21(6):866-73.
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2008: Leoni Giovanna; Patel Hetal B; Sampaio André L F; Gavins Felicity N E; Murray Joanne F; Grieco Paolo; Getting Stephen J; Perretti Mauro
Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(12):4228-38.
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2008: Babbin Brian A; Laukoetter Mike G; Nava Porfirio; Koch Stefan; Lee Winston Y; Capaldo Christopher T; Peatman Eric; Severson Eric A; Flower Roderick J; Perretti Mauro; Parkos Charles A; Nusrat Asma
Annexin A1 regulates intestinal mucosal injury, inflammation, and repair.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):5035-44.
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2008: Dalli Jesmond; Norling Lucy V; Renshaw Derek; Cooper Dianne; Leung Kit-Yi; Perretti Mauro
Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles.
Blood 2008;112(6):2512-9.
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2008: Cooper Dianne; Norling Lucy V; Perretti Mauro
Novel insights into the inhibitory effects of Galectin-1 on neutrophil recruitment under flow.
Journal of leukocyte biology 2008;83(6):1459-66.
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2008: D'Acquisto F; Paschalidis N; Raza K; Buckley C D; Flower R J; Perretti M
Glucocorticoid treatment inhibits annexin-1 expression in rheumatoid arthritis CD4+ T cells.
Rheumatology (Oxford, England) 2008;47(5):636-9.
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2008: Martin Gary R; Perretti Mauro; Flower Roderick J; Wallace John L
Annexin-1 modulates repair of gastric mucosal injury.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(3):G764-9.
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2008: Norling Lucy V; Sampaio André L F; Cooper Dianne; Perretti Mauro
Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(3):682-90.
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2008: Yona Simon; Lin Hsi-Hsien; Dri Pietro; Davies John Q; Hayhoe Richard P G; Lewis Sion M; Heinsbroek Sigrid E M; Brown K Alun; Perretti Mauro; Hamann Jörg; Treacher David F; Gordon Siamon; Stacey Martin
Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(3):741-51.
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2007: Finney Simon J; Anning Peter B; Cao Thong V; Perretti Mauro; Evans Timothy W; Burke-Gaffney Anne
Butanol-extracted lipoteichoic acid induces in vivo leukocyte adhesion.
Biochemical and biophysical research communications 2007;364(4):831-7.
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2007: O'Sullivan Timothy P; Vallin Karl S A; Shah Syed Tasadaque Ali; Fakhry Jérôme; Maderna Paola; Scannell Michael; Sampaio Andre L F; Perretti Mauro; Godson Catherine; Guiry Patrick J
Aromatic lipoxin A4 and lipoxin B4 analogues display potent biological activities.
Journal of medicinal chemistry 2007;50(24):5894-902.
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2007: Gavins Felicity N E; Dalli Jesmond; Flower Roderick J; Granger D Neil; Perretti Mauro
Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(8):1751-8.
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2007: Urquhart Paula; Rosignoli Guglielmo; Cooper Dianne; Motterlini Roberto; Perretti Mauro
Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow.
The Journal of pharmacology and experimental therapeutics 2007;321(2):656-62.
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2007: Mancini Lucia; Paul-Clark Mark J; Rosignoli Guglielmo; Hannon Robert; Martin Jo E; Macintyre Ian; Perretti Mauro
Calcitonin and prednisolone display antagonistic actions on bone and have synergistic effects in experimental arthritis.
The American journal of pathology 2007;170(3):1018-27.
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2007: D'Acquisto Fulvio; Merghani Ahmed; Lecona Emilio; Rosignoli Guglielmo; Raza Karim; Buckley Christopher D; Flower Roderick J; Perretti Mauro
Annexin-1 modulates T-cell activation and differentiation.
Blood 2007;109(3):1095-102.
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2006: Getting Stephen J; Lam Connie W; Leoni Giovanna; Gavins Felicity N E; Grieco Paolo; Perretti Mauro
[D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse).
Molecular pharmacology 2006;70(6):1850-5.
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2006: Getting Stephen J; Lam Connie W; Chen Airu S; Grieco Paolo; Perretti Mauro
Melanocortin 3 receptors control crystal-induced inflammation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(13):2234-41.
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2006: Sawmynaden Prescilla; Perretti Mauro
Glucocorticoid upregulation of the annexin-A1 receptor in leukocytes.
Biochemical and biophysical research communications 2006;349(4):1351-5.
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2006: Yona Simon; Heinsbroek Sigrid E M; Peiser Leanne; Gordon Siamon; Perretti Mauro; Flower Roderick J
Impaired phagocytic mechanism in annexin 1 null macrophages.
British journal of pharmacology 2006;148(4):469-77.
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2006: Perretti Mauro; D'Acquisto Fulvio
Novel aspects of annexin 1 and glucocorticoid biology: intersection with nitric oxide and the lipoxin receptor.
Inflammation & allergy drug targets 2006;5(2):107-14.
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2006: Damazo Amilcar S; Yona Simon; Flower Roderick J; Perretti Mauro; Oliani Sonia M
Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(7):4410-8.
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2006: Gil Cristiane Damas; La Mylinh; Perretti Mauro; Oliani Sonia Maria
Interaction of human neutrophils with endothelial cells regulates the expression of endogenous proteins annexin 1, galectin-1 and galectin-3.
Cell biology international 2006;30(4):338-44.
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2006: Gil C D; Cooper D; Rosignoli G; Perretti M; Oliani S M
Inflammation-induced modulation of cellular galectin-1 and -3 expression in a model of rat peritonitis.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2006;55(3):99-107.
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2006: Hayhoe Richard P G; Kamal Ahmad M; Solito Egle; Flower Roderick J; Cooper Dianne; Perretti Mauro
Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement.
Blood 2006;107(5):2123-30.
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2006: Getting Stephen J; Di Filippo Clara; D'Amico Michele; Perretti Mauro
The melanocortin peptide HP228 displays protective effects in acute models of inflammation and organ damage.
European journal of pharmacology 2006;532(1-2):138-44.
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2006: Lam Connie W; Perretti Mauro; Getting Stephen J
Melanocortin receptor signaling in RAW264.7 macrophage cell line.
Peptides 2006;27(2):404-12.
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2006: Kamal Ahmad M; Hayhoe Richard P G; Paramasivam Anbalakan; Cooper Dianne; Flower Roderick J; Solito Egle; Perretti Mauro
Antiflammin-2 activates the human formyl-peptide receptor like 1.
TheScientificWorldJournal 2006;6():1375-84.
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2005: Moraes Leonardo A; Paul-Clark Mark J; Rickman Alice; Flower Roderick J; Goulding Nicolas J; Perretti Mauro
Ligand-specific glucocorticoid receptor activation in human platelets.
Blood 2005;106(13):4167-75.
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2005: Chatterjee Bristi E; Yona Simon; Rosignoli Guglielmo; Young Rebecca E; Nourshargh Sussan; Flower Roderick J; Perretti Mauro
Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro.
Journal of leukocyte biology 2005;78(3):639-46.
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2005: Gavins F N E; Sawmynaden P; Chatterjee B E; Perretti M
A twist in anti-inflammation: annexin 1 acts via the lipoxin A4 receptor.
Prostaglandins, leukotrienes, and essential fatty acids 2005;73(3-4):211-9.
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2005: Damazo Amilcar S; Yona Simon; D'Acquisto Fulvio; Flower Roderick J; Oliani Sonia M; Perretti Mauro
Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation.
The American journal of pathology 2005;166(6):1607-17.
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2005: Kamal Ahmad M; Flower Roderick J; Perretti Mauro
An overview of the effects of annexin 1 on cells involved in the inflammatory process.
Memórias do Instituto Oswaldo Cruz 2005;100 Suppl 1():39-47.
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2005: Flower Roderick J; Perretti Mauro
Controlling inflammation: a fat chance?
The Journal of experimental medicine 2005;201(5):671-4.
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2005: Lam Connie W; Getting Stephen J; Perretti Mauro
In vitro and in vivo induction of heme oxygenase 1 in mouse macrophages following melanocortin receptor activation.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(4):2297-304.
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2005: Yona S; Ward Barbara; Buckingham Julia C; Perretti M; Flower R J
Macrophage biology in the Anx-A1-/- mouse.
Prostaglandins, leukotrienes, and essential fatty acids 2005;72(2):95-103.
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2005: Gavins Felicity N E; Kamal Ahmad M; D'Amico Michele; Oliani Sonia M; Perretti Mauro
Formyl-peptide receptor is not involved in the protection afforded by annexin 1 in murine acute myocardial infarct.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(1):100-2.
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2004: Cao Thong V; La Mylinh; Getting Stephen J; Day Anthony J; Perretti Mauro
Inhibitory effects of TSG-6 Link module on leukocyte-endothelial cell interactions in vitro and in vivo.
Microcirculation (New York, N.Y. : 1994) 2004;11(7):615-24.
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2004: Getting Stephen J; Di Filippo Clara; Christian Helen C; Lam Connie W; Rossi Francesco; D'Amico Michele; Perretti Mauro
MC-3 receptor and the inflammatory mechanisms activated in acute myocardial infarct.
Journal of leukocyte biology 2004;76(4):845-53.
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2004: Di Filippo Clara; Rossi Francesco; Ongini Ennio; Del Soldato Piero; Perretti Mauro; D'Amico Michele
The distinct alterations produced in cardiovascular functions by prednisolone and nitro-prednisolone (NCX-1015) in the rat highlight a causal role for endothelin-1.
The Journal of pharmacology and experimental therapeutics 2004;310(3):1133-41.
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2004: Yona Simon; Buckingham Julia C; Perretti Mauro; Flower Roderick J
Stimulus-specific defect in the phagocytic pathways of annexin 1 null macrophages.
British journal of pharmacology 2004;142(5):890-8.
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2004: Perretti M; Solito E
Annexin 1 and neutrophil apoptosis.
Biochemical Society transactions 2004;32(Pt3):507-10.
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2004: Young Rebecca E; Thompson Richard D; Larbi Karen Y; La Mylinh; Roberts Clare E; Shapiro Steven D; Perretti Mauro; Nourshargh Sussan
Neutrophil elastase (NE)-deficient mice demonstrate a nonredundant role for NE in neutrophil migration, generation of proinflammatory mediators, and phagocytosis in response to zymosan particles in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4493-502.
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2004: Yang Yuan H; Morand Eric F; Getting Stephen J; Paul-Clark Mark; Liu Dong L; Yona Simon; Hannon Robert; Buckingham Julia C; Perretti Mauro; Flower Roderick J
Modulation of inflammation and response to dexamethasone by Annexin 1 in antigen-induced arthritis.
Arthritis and rheumatism 2004;50(3):976-84.
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2004: Moraes Leonardo A; Giner Rosa M; Paul-Clark Mark J; Perretti Mauro; Perrett David
An isocratic HPLC method for the quantitation of eicosanoids in human platelets.
Biomedical chromatography : BMC 2004;18(1):64-8.
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2004: Baraldi Pier Giovanni; Romagnoli Romeo; Del Carmen Nuñez Maria; Perretti Mauro; Paul-Clark Mark J; Ferrario Massimiliano; Govoni Mirco; Benedini Francesca; Ongini Ennio
Synthesis of nitro esters of prednisolone, new compounds combining pharmacological properties of both glucocorticoids and nitric oxide.
Journal of medicinal chemistry 2004;47(3):711-9.
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2003: Perretti Mauro
The annexin 1 receptor(s): is the plot unravelling?
Trends in pharmacological sciences 2003;24(11):574-9.
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2003: La Mylinh; Cao Thong V; Cerchiaro Graziela; Chilton Kathya; Hirabayashi Jun; Kasai Ken-Ichi; Oliani Sonia M; Chernajovsky Yuti; Perretti Mauro
A novel biological activity for galectin-1: inhibition of leukocyte-endothelial cell interactions in experimental inflammation.
The American journal of pathology 2003;163(4):1505-15.
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2003: Paul-Clark Mark J; Roviezzo Fiorentina; Flower Roderick J; Cirino Giuseppe; Soldato Piero Del; Adcock Ian M; Perretti Mauro
Glucocorticoid receptor nitration leads to enhanced anti-inflammatory effects of novel steroid ligands.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):3245-52.
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2003: Solito Egle; Kamal Ahmad; Russo-Marie Francoise; Buckingham Julia C; Marullo Stefano; Perretti Mauro
A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(11):1544-6.
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2003: Getting Stephen J; Schiöth Helgi B; Perretti Mauro
Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides.
The Journal of pharmacology and experimental therapeutics 2003;306(2):631-7.
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2003: Perretti M; Paul-Clark M J; Mancini L; Flower R J
Generation of innovative anti-inflammatory and anti-arthritic glucocorticoid derivatives that release NO: the nitro-steroids.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2003;35 Suppl 2():S41-8.
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2003: Gavins Felicity N E; Yona Simon; Kamal Ahmad M; Flower Roderick J; Perretti Mauro
Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms.
Blood 2003;101(10):4140-7.
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2003: Perretti Mauro; Gavins Felicity N E
Annexin 1: an endogenous anti-inflammatory protein.
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 2003;18():60-4.
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2003: Getting Stephen J; Christian Helen C; Lam Connie W; Gavins Felicity N E; Flower Roderick J; Schiöth Helgi B; Perretti Mauro
Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):3323-30.
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2003: Hannon Robert; Croxtall Jamie D; Getting Steve J; Roviezzo Fiorita; Yona Simon; Paul-Clark Mark J; Gavins Felicity N E; Perretti Mauro; Morris John F; Buckingham Julia C; Flower Roderick J
Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(2):253-5.
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2003: Perretti Mauro; Getting Stephen J
Migration of specific leukocyte subsets in response to cytokine or chemokine application in vivo.
Methods in molecular biology (Clifton, N.J.) 2003;225():139-46.
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2002: Roviezzo F; Getting S J; Paul-Clark M J; Yona S; Gavins F N E; Perretti M; Hannon R; Croxtall J D; Buckingham J C; Flower R J
The annexin-1 knockout mouse: what it tells us about the inflammatory response.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2002;53(4 Pt 1):541-53.
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2002: Getting Stephen J; Mahoney David J; Cao Thong; Rugg Marilyn S; Fries Erik; Milner Caroline M; Perretti Mauro; Day Anthony J
The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner.
The Journal of biological chemistry 2002;277(52):51068-76.
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2002: Perretti Mauro; Chiang Nan; La Mylinh; Fierro Iolanda M; Marullo Stefano; Getting Stephen J; Solito Egle; Serhan Charles N
Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor.
Nature medicine 2002;8(11):1296-302.
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2002: Oliani Sonia M; Damazo Amilcar S; Perretti Mauro
Annexin 1 localisation in tissue eosinophils as detected by electron microscopy.
Mediators of inflammation 2002;11(5):287-92.
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2002: Getting Stephen J; Christian Helen C; Flower Roderick J; Perretti Mauro
Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis.
Arthritis and rheumatism 2002;46(10):2765-75.
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2002: Perretti Mauro; Ingegnoli Francesca; Wheller Samantha K; Blades Mark C; Solito Egle; Pitzalis Costantino
Annexin 1 modulates monocyte-endothelial cell interaction in vitro and cell migration in vivo in the human SCID mouse transplantation model.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(4):2085-92.
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2002: Gibbs L; Carollo M G; Damazo A S; Oliani S M; Perretti M
Time-dependent expression of annexin 1 in a model of chronic granulomatous inflammation.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51(6):300-6.
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2002: Blades Mark C; Manzo Antonio; Ingegnoli Francesca; Taylor Peter R; Panayi Gabriel S; Irjala Heikki; Jalkanen Sirpa; Haskard Dorian O; Perretti Mauro; Pitzalis Costantino
Stromal cell-derived factor 1 (CXCL12) induces human cell migration into human lymph nodes transplanted into SCID mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4308-17.
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2002: Ingegnoli F; Blades M; Manzo A; Wahid S; Perretti M; Panayi G; Pitzalis C
[Role of cell migration in the pathogenesis of rheumatoid arthritis: in vivo studies in SCID mice transplanted with human synovial membrane]
Reumatismo 2002;54(2):128-32.
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2002: Blades M C; Ingegnoli F; Wheller S K; Manzo A; Wahid S; Panayi G S; Perretti M; Pitzalis C
Stromal cell-derived factor 1 (CXCL12) induces monocyte migration into human synovium transplanted onto SCID Mice.
Arthritis and rheumatism 2002;46(3):824-36.
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2002: Paul-Clark Mark J; Mancini Lucia; Del Soldato Piero; Flower Roderick J; Perretti Mauro
Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1677-82.
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2001: La M; D'Amico M; Bandiera S; Di Filippo C; Oliani S M; Gavins F N; Flower R J; Perretti M
Annexin 1 peptides protect against experimental myocardial ischemia-reperfusion: analysis of their mechanism of action.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(12):2247-56.
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2001: de Coupade C; Ajuebor M N; Russo-Marie F; Perretti M; Solito E
Cytokine modulation of liver annexin 1 expression during experimental endotoxemia.
The American journal of pathology 2001;159(4):1435-43.
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2001: Getting S J; Perretti M
Arthritic diseases: melanocortin type 3 receptor agonists as potential therapeutics.
Current opinion in investigational drugs (London, England : 2000) 2001;2(8):1064-9.
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2001: Damazo A S; Tavares de Lima W; Perretti M; Oliani S M
Pharmacological modulation of allergic inflammation in the rat airways and association with mast cell heterogeneity.
European journal of pharmacology 2001;426(1-2):123-30.
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2001: Solito E; de Coupade C; Canaider S; Goulding N J; Perretti M
Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase-3 activation.
British journal of pharmacology 2001;133(2):217-28.
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2001: Oliani S M; Paul-Clark M J; Christian H C; Flower R J; Perretti M
Neutrophil interaction with inflamed postcapillary venule endothelium alters annexin 1 expression.
The American journal of pathology 2001;158(2):603-15.
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2001: Getting S J; Allcock G H; Flower R; Perretti M
Natural and synthetic agonists of the melanocortin receptor type 3 possess anti-inflammatory properties.
Journal of leukocyte biology 2001;69(1):98-104.
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2001: Oliani S M; Lim L H; Christian H C; Pell K; Das A M; Perretti M
Morphological alteration of peritoneal mast cells and macrophages in the mouse peritoneal cavity during the early phases of an allergic inflammatory reaction.
Cell biology international 2001;25(8):795-803.
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2000: Mancini L; Moradi-Bidhendi N; Brandi M L; Perretti M; MacIntyre I
Modulation of the effects of osteoprotegerin (OPG) ligand in a human leukemic cell line by OPG and calcitonin.
Biochemical and biophysical research communications 2000;279(2):391-7.
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2000: Paul-Clark M; Del Soldato P; Fiorucci S; Flower R J; Perretti M
21-NO-prednisolone is a novel nitric oxide-releasing derivative of prednisolone with enhanced anti-inflammatory properties.
British journal of pharmacology 2000;131(7):1345-54.
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2000: D'Amico M; Di Filippo C; La M; Solito E; McLean P G; Flower R J; Oliani S M; Perretti M
Lipocortin 1 reduces myocardial ischemia-reperfusion injury by affecting local leukocyte recruitment.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(13):1867-9.
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2000: Oliani S M; Christian H C; Manston J; Flower R J; Perretti M
An immunocytochemical and in situ hybridization analysis of annexin 1 expression in rat mast cells: modulation by inflammation and dexamethasone.
Laboratory investigation; a journal of technical methods and pathology 2000;80(9):1429-38.
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2000: McLean P G; Ahluwalia A; Perretti M
Association between kinin B(1) receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules.
The Journal of experimental medicine 2000;192(3):367-80.
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2000: Perretti M; Page C P
Heparin and inflammation: a new use for an old GAG?
Gut 2000;47(1):14-5.
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2000: Perretti M; Ahluwalia A
The microcirculation and inflammation: site of action for glucocorticoids.
Microcirculation (New York, N.Y. : 1994) 2000;7(3):147-61.
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2000: Lim L H; Flower R J; Perretti M; Das A M
Glucocorticoid receptor activation reduces CD11b and CD49d levels on murine eosinophils: characterization and functional relevance.
American journal of respiratory cell and molecular biology 2000;22(6):693-701.
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2000: Canaider S; Solito E; de Coupade C; Flower R J; Russo-Marie F; Goulding N J; Perretti M
Increased apoptosis in U937 cells over-expressing lipocortin 1 (annexin I).
Life sciences 2000;66(18):PL265-70.
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2000: Perretti M; Christian H; Wheller S K; Aiello I; Mugridge K G; Morris J F; Flower R J; Goulding N J
Annexin I is stored within gelatinase granules of human neutrophil and mobilized on the cell surface upon adhesion but not phagocytosis.
Cell biology international 2000;24(3):163-74.
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1999: Getting S J; Flower R J; Perretti M
Agonism at melanocortin receptor type 3 on macrophages inhibits neutrophil influx.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48 Suppl 2():S140-1.
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1999: Tailor A; Tomlinson A; Salas A; Panés J; Granger D N; Flower R J; Perretti M
Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC.
Gut 1999;45(5):705-12.
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1999: Das A M; Ajuebor M N; Flower R J; Perretti M; McColl S R
Contrasting roles for RANTES and macrophage inflammatory protein-1 alpha (MIP-1 alpha) in a murine model of allergic peritonitis.
Clinical and experimental immunology 1999;117(2):223-9.
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1999: Getting S J; Gibbs L; Clark A J; Flower R J; Perretti M
POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7446-53.
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1999: Perretti M; Wheller S K; Flower R J; Wahid S; Pitzalis C
Modulation of cellular annexin I in human leukocytes infiltrating DTH skin reactions.
Journal of leukocyte biology 1999;65(5):583-9.
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1999: Ajuebor M N; Das A M; Virág L; Szabó C; Perretti M
Regulation of macrophage inflammatory protein-1 alpha expression and function by endogenous interleukin-10 in a model of acute inflammation.
Biochemical and biophysical research communications 1999;255(2):279-82.
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1999: Ajuebor M N; Das A M; Virág L; Flower R J; Szabó C; Perretti M
Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1685-91.
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1999: Euzger H S; Flower R J; Goulding N J; Perretti M
Differential modulation of annexin I binding sites on monocytes and neutrophils.
Mediators of inflammation 1999;8(1):53-62.
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1998: Ajuebor M N; Virág L; Flower R J; Perretti M; Szabó C
Role of inducible nitric oxide synthase in the regulation of neutrophil migration in zymosan-induced inflammation.
Immunology 1998;95(4):625-30.
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1998: Lim L H; Solito E; Russo-Marie F; Flower R J; Perretti M
Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: effect of lipocortin 1.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14535-9.
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1998: Goulding N J; Euzger H S; Butt S K; Perretti M
Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1998;47 Suppl 3():S158-65.
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1998: Perretti M
Lipocortin 1 and chemokine modulation of granulocyte and monocyte accumulation in experimental inflammation.
General pharmacology 1998;31(4):545-52.
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1998: Ajuebor M N; Gibbs L; Flower R J; Das A M; Perretti M
Investigation of the functional role played by the chemokine monocyte chemoattractant protein-1 in interleukin-1-induced murine peritonitis.
British journal of pharmacology 1998;125(2):319-26.
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1998: Das A M; Flower R J; Perretti M
Resident mast cells are important for eotaxin-induced eosinophil accumulation in vivo.
Journal of leukocyte biology 1998;64(2):156-62.
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1998: Bryant C E; Perretti M; Flower R J
Suppression by dexamethasone of inducible nitric oxide synthase protein expression in vivo: a possible role for lipocortin 1.
Biochemical pharmacology 1998;55(3):279-85.
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1998: Ajuebor M N; Flower R J; Hannon R; Christie M; Bowers K; Verity A; Perretti M
Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model.
Journal of leukocyte biology 1998;63(1):108-16.
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1997: Perretti M
Endogenous mediators that inhibit the leukocyte-endothelium interaction.
Trends in pharmacological sciences 1997;18(11):418-25.
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1997: Getting S J; Flower R J; Parente L; de Medicis R; Lussier A; Woliztky B A; Martins M A; Perretti M
Molecular determinants of monosodium urate crystal-induced murine peritonitis: a role for endogenous mast cells and a distinct requirement for endothelial-derived selectins.
The Journal of pharmacology and experimental therapeutics 1997;283(1):123-30.
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1997: Tailor A; Flower R J; Perretti M
Dexamethasone inhibits leukocyte emigration in rat mesenteric post-capillary venules: an intravital microscopy study.
Journal of leukocyte biology 1997;62(3):301-8.
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1997: Das A M; Flower R J; Perretti M
Eotaxin-induced eosinophil migration in the peritoneal cavity of ovalbumin-sensitized mice: mechanism of action.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(3):1466-73.
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1997: Wheller S K; Perretti M
Dexamethasone inhibits cytokine-induced intercellular adhesion molecule-1 up-regulation on endothelial cell lines.
European journal of pharmacology 1997;331(1):65-71.
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1997: Das A M; Flower R J; Hellewell P G; Teixeira M M; Perretti M
A novel murine model of allergic inflammation to study the effect of dexamethasone on eosinophil recruitment.
British journal of pharmacology 1997;121(1):97-104.
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1997: Getting S J; Flower R J; Perretti M
Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1.
British journal of pharmacology 1997;120(6):1075-82.
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1997: Tailor A; Das A M; Getting S J; Flower R J; Perretti M
Subacute treatment of rats with dexamethasone reduces ICAM-1 levels on circulating monocytes.
Biochemical and biophysical research communications 1997;231(3):675-8.
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1996: Perretti M; Croxtall J D; Wheller S K; Goulding N J; Hannon R; Flower R J
Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration.
Nature medicine 1996;2(11):1259-62.
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1996: Perretti M; Flower R J
Measurement of lipocortin 1 levels in murine peripheral blood leukocytes by flow cytometry: modulation by glucocorticoids and inflammation.
British journal of pharmacology 1996;118(3):605-10.
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1996: Perretti M; Wheller S K; Harris J G; Flower R J
Modulation of ICAM-1 levels on U-937 cells and mouse macrophages by interleukin-1 beta and dexamethasone.
Biochemical and biophysical research communications 1996;223(1):112-7.
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1996: Harris J G; Flower R J; Watanabe K; Tsurufuji S; Wolitzky B A; Perretti M
Relative contribution of the selectins in the neutrophil recruitment caused by the chemokine cytokine-induced neutrophil chemoattractant (CINC).
Biochemical and biophysical research communications 1996;221(3):692-6.
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1996: Perretti M; Ahluwalia A; Harris J G; Harris H J; Wheller S K; Flower R J
Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1.
British journal of pharmacology 1996;117(6):1145-54.
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1996: Ahluwalia A; Perretti M
Involvement of bradykinin B1 receptors in the polymorphonuclear leukocyte accumulation induced by IL-1 beta in vivo in the mouse.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(1):269-74.
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1995: Mugridge K G; Perretti M; Ghiara P; Galeotti C L; Melli M; Parente L
Gastric antisecretory and anti-ulcer actions of IL-1 in rat involve different IL-1 receptor types.
The American journal of physiology 1995;269(5 Pt 1):G763-9.
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1995: Perretti M; Szabó C; Thiemermann C
Effect of interleukin-4 and interleukin-10 on leucocyte migration and nitric oxide production in the mouse.
British journal of pharmacology 1995;116(4):2251-7.
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1995: Perretti M; Wheller S K; Choudhury Q; Croxtall J D; Flower R J
Selective inhibition of neutrophil function by a peptide derived from lipocortin 1 N-terminus.
Biochemical pharmacology 1995;50(7):1037-42.
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1995: Harris J G; Flower R J; Perretti M
Endogenous corticosteroids mediate the neutrophilia caused by platelet-activating factor in the mouse.
European journal of pharmacology 1995;283(1-3):9-18.
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1995: Palmi M; Frosini M; Sgaragli G P; Becherucci C; Perretti M; Parente L
Inhibition of interleukin-1 beta-induced pyresis in the rabbit by peptide 204-212 of lipocortin 5.
European journal of pharmacology 1995;281(1):97-9.
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1995: Klemm P; Harris H J; Perretti M
Effect of rolipram in a murine model of acute inflammation: comparison with the corticoid dexamethasone.
European journal of pharmacology 1995;281(1):69-74.
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1995: Mancuso F; Flower R J; Perretti M
Leukocyte transmigration, but not rolling or adhesion, is selectively inhibited by dexamethasone in the hamster post-capillary venule. Involvement of endogenous lipocortin 1.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(1):377-86.
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1995: Harris J G; Flower R J; Perretti M
Alteration of neutrophil trafficking by a lipocortin 1 N-terminus peptide.
European journal of pharmacology 1995;279(2-3):149-57.
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1995: Wu C C; Croxtall J D; Perretti M; Bryant C E; Thiemermann C; Flower R J; Vane J R
Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3473-7.
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1995: Perretti M; Flower R J
Anti-inflammatory lipocortin-derived peptides.
Agents and actions. Supplements 1995;46():131-8.
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1994: Ahluwalia A; Perretti M
Calcitonin gene-related peptides modulate the acute inflammatory response induced by interleukin-1 in the mouse.
European journal of pharmacology 1994;264(3):407-15.
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1994: Perretti M; Flower R J
Cytokines, glucocorticoids and lipocortins in the control of neutrophil migration.
Pharmacological research : the official journal of the Italian Pharmacological Society 1994;30(1):53-9.
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1994: Perretti M; Harris J G; Flower R J
A role for endogenous histamine in interleukin-8-induced neutrophil infiltration into mouse air-pouch: investigation of the modulatory action of systemic and local dexamethasone.
British journal of pharmacology 1994;112(3):801-8.
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1994: Perretti M
Lipocortin-derived peptides.
Biochemical pharmacology 1994;47(6):931-8.
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1994: Ahluwalia A; Perretti M
Anti-inflammatory effect of prostanoids in mouse and rat skin: evidence for a role of EP3-receptors.
The Journal of pharmacology and experimental therapeutics 1994;268(3):1526-31.
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1993: Perretti M; Ahluwalia A; Harris J G; Goulding N J; Flower R J
Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(8):4306-14.
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1993: Perretti M; Duncan G S; Flower R J; Peers S H
Serum corticosterone, interleukin-1 and tumour necrosis factor in rat experimental endotoxaemia: comparison between Lewis and Wistar strains.
British journal of pharmacology 1993;110(2):868-74.
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1993: Perretti M; Ahluwalia A; Flower R J; Manzini S
Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: involvement of NK-1 receptors.
Immunology 1993;80(1):73-7.
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1993: Perretti M; Flower R J; Goulding N J
The ability of murine leukocytes to bind lipocortin 1 is lost during acute inflammation.
Biochemical and biophysical research communications 1993;192(2):345-50.
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1993: Da Silva J A; Peers S H; Perretti M; Willoughby D A
Sex steroids affect glucocorticoid response to chronic inflammation and to interleukin-1.
The Journal of endocrinology 1993;136(3):389-97.
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1993: Croxtall J; Flower R; Perretti M
The role of lipocortin 1 in the regulation of A549 cell proliferation and leukocyte migration.
Journal of lipid mediators 1993;6(1-3):295-302.
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1993: Perretti M; Flower R J
Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(3):992-9.
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1993: Perretti M; Appleton I; Parente L; Flower R J
Pharmacology of interleukin-1-induced neutrophil migration.
Agents and actions 1993;38 Spec No():C64-5.
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1992: Douglas G J; Flower R J; Parente L; Perretti M
Peptide 204-212 of lipocortin 5 inhibits the generation of a prostacyclin-like factor from rat aorta preparations in vitro.
Prostaglandins 1992;44(5):381-8.
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1992: Parente L; Perretti M; Wallace J L; Mugridge K G
Mechanism of the protective action of interleukin-1 in the experimental gastric damage in the rat.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():28-9.
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1992: Perretti M; Mugridge K G; Wallace J L; Parente L
Reduction of aspirin-induced gastric damage in rats by interleukin-1 beta: possible involvement of endogenous corticosteroids.
The Journal of pharmacology and experimental therapeutics 1992;261(3):1238-47.
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1992: Perretti M; Solito E; Parente L
Evidence that endogenous interleukin-1 is involved in leukocyte migration in acute experimental inflammation in rats and mice.
Agents and actions 1992;35(1-2):71-8.
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1992: Becherucci C; Perretti M; Nencioni L; Silvestri S; Parente L
Anti-inflammatory effect of tuftsin and its retro-inverso analogue in rat adjuvant arthritis.
Agents and actions 1992;Spec No():C115-7.
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1991: Verdini A S; Silvestri S; Becherucci C; Longobardi M G; Parente L; Peppoloni S; Perretti M; Pileri P; Pinori M; Viscomi G C
Immunostimulation by a partially modified retro-inverso-tuftsin analogue containing Thr1 psi[NHCO](R,S)Lys2 modification.
Journal of medicinal chemistry 1991;34(12):3372-9.
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1991: Perretti M; Mugridge K G; Becherucci C; Parente L
Evidence that interleukin-1 and lipoxygenase metabolites mediate the lethal effect of complete Freund's adjuvant in adrenalectomized rats.
Lymphokine and cytokine research 1991;10(4):239-43.
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1991: Perretti M; Becherucci C; Mugridge K G; Solito E; Silvestri S; Parente L
A novel anti-inflammatory peptide from human lipocortin 5.
British journal of pharmacology 1991;103(2):1327-32.
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1991: Mugridge K G; Perretti M; Ghiara P; Parente L
Alpha-melanocyte-stimulating hormone reduces interleukin-1 beta effects on rat stomach preparations possibly through interference with a type I receptor.
European journal of pharmacology 1991;197(2-3):151-5.
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1991: Mugridge K G; Perretti M; Becherucci C; Parente L
Persistent effects of interleukin-1 on smooth muscle preparations from adrenalectomized rats: implications for increased phospholipase-A2 activity via stimulation of 5-lipoxygenase.
The Journal of pharmacology and experimental therapeutics 1991;256(1):29-37.
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1991: Mugridge K G; Perretti M; Parente L
5-Lipoxygenase activation may facilitate an interleukin-1 transduction signal.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21B():517-20.
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1990: Becherucci C; Solito E; Perretti M; Mugridge K G; Galeotti C L; Parente L
Purification and biological activity of human lipocortin 2.
Pharmacological research : the official journal of the Italian Pharmacological Society 1990;22 Suppl 1():29-30.
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1990: Perretti M; Nuti S; Parente L
Investigation of rat mast cell degranulation using flow cytometry.
Journal of pharmacological methods 1990;23(3):187-94.
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1990: Parente L; Becherucci C; Perretti M; Solito E; Mugridge K G; Galeotti C L; Raugei G; Melli M; Sanso M
Are the lipocortins the second messengers of the anti-inflammatory action of glucocorticoids?
Progress in clinical and biological research 1990;349():55-68.
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1989: Perretti M; Becherucci C; Scapigliati G; Parente L
The effect of adrenalectomy on interleukin-1 release in vitro and in vivo.
British journal of pharmacology 1989;98(4):1137-42.
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1989: Becherucci C; Donati D; Perretti M; Parente L
The release of interleukin-1-like activity by macrophages in two models of immunological inflammation in the rat.
Agents and actions 1989;28(3-4):243-7.
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