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Michel Perricaudet

Research Profile

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Gene Transfer Techniques

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Anastasia Lanzi; Ghada Ben Youssef; Michel Perricaudet; Karim Benihoud
Anti-adenovirus humoral responses influence on the efficacy of vaccines based on epitope display on adenovirus capsid.
Racha Karaky; Emilie Gobbo; Paule Opolon; Jean Delbé; José Courty; Frank Griscelli; Michel Perricaudet; Dominique Martel-Renoir
HARPΔ111-136 enhances radiation-induced apoptosis of U87MG glioblastoma by induction of the proapoptotic protein CHOP.
H Li; X Shi; J Liu; C Hu; X Zhang; H Liu; J Jin; Paule Opolon; J-P Vannier; Michel Perricaudet; A Janin; Claudine Soria; H Lu
The soluble fragment of VE-cadherin inhibits angiogenesis by reducing endothelial cell proliferation and tube capillary formation.

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All Publications

2011: Anastasia Lanzi; Ghada Ben Youssef; Michel Perricaudet; Karim Benihoud
Anti-adenovirus humoral responses influence on the efficacy of vaccines based on epitope display on adenovirus capsid.
Vaccine 2011;29(7):1463-71.
2011: Racha Karaky; Emilie Gobbo; Paule Opolon; Jean Delbé; José Courty; Frank Griscelli; Michel Perricaudet; Dominique Martel-Renoir
HARPΔ111-136 enhances radiation-induced apoptosis of U87MG glioblastoma by induction of the proapoptotic protein CHOP.
International journal of oncology 2011;38(1):179-88.
2010: H Li; X Shi; J Liu; C Hu; X Zhang; H Liu; J Jin; Paule Opolon; J-P Vannier; Michel Perricaudet; A Janin; Claudine Soria; H Lu
The soluble fragment of VE-cadherin inhibits angiogenesis by reducing endothelial cell proliferation and tube capillary formation.
Cancer gene therapy 2010;17(10):700-7.
2010: Célia Dos Santos; Racha Karaky; Dominique Renoir; Yamina Hamma-Kourbali; Patricia Albanese; Emilie Gobbo; Frank Griscelli; Paule Opolon; Sophie Dalle; Michel Perricaudet; José Courty; Jean Delbé
Antitumorigenic effects of a mutant of the heparin affin regulatory peptide on the U87 MG glioblastoma cell line.
International journal of cancer. Journal international du cancer 2010;127(5):1038-51.
2009: B Jullienne; F Vigant; E Muth; R Chaligné; Céline Bouquet; Stéphane Giraudier; Michel Perricaudet; Karim Benihoud
Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid.
Gene therapy 2009;16(12):1405-15.
2008: Vanessa Fritz; Danièle Noël; Céline Bouquet; Paule Opolon; Romain Voide; Florence Apparailly; Pascale Louis-Plence; Carine Bouffi; Hicham Drissi; Chao Xie; Michel Perricaudet; Ralph Müller; Edward Schwarz; Christian Jorgensen
Antitumoral activity and osteogenic potential of mesenchymal stem cells expressing the urokinase-type plasminogen antagonist amino-terminal fragment in a murine model of osteolytic tumor.
Stem cells (Dayton, Ohio) 2008;26(11):2981-90.
2008: Claire Magnon; Paule Opolon; Elisabeth Connault; Lluis M Mir; Michel Perricaudet; Dominique Martel-Renoir
Canstatin gene electrotransfer combined with radiotherapy: preclinical trials for cancer treatment.
Gene therapy 2008;15(21):1436-45.
2008: Aurélie Ducès; Racha Karaky; Dominique Martel-Renoir; Lluis Mir; Yamina Hamma-Kourbali; Ivan Biéche; Paule Opolon; Jean Delbé; José Courty; Michel Perricaudet; Frank Griscelli
16-kDa fragment of pleiotrophin acts on endothelial and breast tumor cells and inhibits tumor development.
Molecular cancer therapeutics 2008;7(9):2817-27.
2008: Frédéric Vigant; Delphyne Descamps; Betsy Jullienne; Stéphanie Esselin; Elisabeth Connault; Paule Opolon; Thierry Tordjmann; Emmanuelle Vigne; Michel Perricaudet; Karim Benihoud
Substitution of hexon hypervariable region 5 of adenovirus serotype 5 abrogates blood factor binding and limits gene transfer to liver.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(8):1474-80.
2007: Didier Marot; Ivan Bieche; Chantal Aumas; Stéphanie Esselin; Céline Bouquet; Sophie Vacher; Gwendal Lazennec; Michel Perricaudet; Frédérique Kuttenn; Rosette Lidereau; Nicolas de Roux
High tumoral levels of Kiss1 and G-protein-coupled receptor 54 expression are correlated with poor prognosis of estrogen receptor-positive breast tumors.
Endocrine-related cancer 2007;14(3):691-702.
2007: Claire Magnon; Paule Opolon; Marcel Ricard; Elisabeth Connault; Patrice Ardouin; Ariane Galaup; Didier Métivier; Jean-Michel Bidart; Stéphane Germain; Michel Perricaudet; Martin Schlumberger
Radiation and inhibition of angiogenesis by canstatin synergize to induce HIF-1alpha-mediated tumor apoptotic switch.
The Journal of clinical investigation 2007;117(7):1844-55.
2007: Karim Benihoud; Stéphanie Esselin; D Descamps; B Jullienne; Barbara Salone; Pierre Bobé; Danielle Bonardelle; Elisabeth Connault; Paule Opolon; Isabella Saggio; Michel Perricaudet
Respective roles of TNF-alpha and IL-6 in the immune response-elicited by adenovirus-mediated gene transfer in mice.
Gene therapy 2007;14(6):533-44.
2007: Eric Frau; Claire Magnon; Paule Opolon; Elisabeth Connault; David Opolon; F Beermann; F Beerman; marc Mordekhaï ABITBOL; Michel Perricaudet; Céline Bouquet
A gene transfer comparative study of HSA-conjugated antiangiogenic factors in a transgenic mouse model of metastatic ocular cancer.
Cancer gene therapy 2007;14(3):251-61.
2007: Thomas Gastinne; Frédéric Vigant; Cecile Lavenu-Bombled; Orianne Wagner-Ballon; Micheline Tulliez; Hédia Chagraoui; Jean-Luc Villeval; Catherine Lacout; Michel Perricaudet; William Vainchenker; Karim Benihoud; Stéphane Giraudier
Adenoviral-mediated TGF-beta1 inhibition in a mouse model of myelofibrosis inhibit bone marrow fibrosis development.
Experimental hematology 2007;35(1):64-74.
2007: Claire Magnon; Ariane Galaup; Valérie Rouffiac; Paule Opolon; Elisabeth Connault; M Rosé; Michel Perricaudet; Alain Roche; Stéphane Germain; Frank Griscelli; Nathalie Lassau
Dynamic assessment of antiangiogenic therapy by monitoring both tumoral vascularization and tissue degeneration.
Gene therapy 2007;14(2):108-17.
2006: Xiao-Yu Shi; He Lu; Wen-Lin Li; Hong-Lin Tang; Jian-Jun Xiong; Ji-Qing Zhang; Paule Opolon; Chantal Legrand; Michel Perricaudet; Hong Li
A soluble truncated cadherin induces breast cancer cell apoptosis and growth inhibition.
Journal of cancer research and clinical oncology 2006;132(9):561-71.
2006: Delphyne Descamps; Frédéric Vigant; Stéphanie Esselin; Elisabeth Connault; Paule Opolon; Michel Perricaudet; Karim Benihoud
Expression of non-signaling membrane-anchored death receptors protects murine livers in different models of hepatitis.
Hepatology (Baltimore, Md.) 2006;44(2):399-409.
2006: Céline Bouquet; Noël Lamandé; Marcus Brand; Jean-Marie Gasc; Betsy Jullienne; Gabrielle Faure; Frank Griscelli; Paule Opolon; Elisabeth Connault; Michel Perricaudet; Pierre Corvol
Suppression of angiogenesis, tumor growth, and metastasis by adenovirus-mediated gene transfer of human angiotensinogen.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(2):175-82.
2006: Benoît Hosten; Désiré Challuau; Sophie Gil; Céline Bouquet; Sylvie Marion; Michel Perricaudet; Mario Di Palma; Robert Farinotti; Laurence Bonhomme-Faivre
Recombinant interleukin-2 pre-treatment increases anti-tumor response to paclitaxel by affecting lung P-glycoprotein expression on the Lewis lung carcinoma.
Anti-cancer drugs 2006;17(2):195-9.
2006: Didier Marot; Paule Opolon; S Brailly-Tabard; N Elie; Voahangy Randrianarison; Elisabeth Connault; Nicolas Foray; Jean Feunteun; Michel Perricaudet
The tumor suppressor activity induced by adenovirus-mediated BRCA1 overexpression is not restricted to breast cancers.
Gene therapy 2006;13(3):235-44.
2005: Hong Li; Claudine Soria; Frank Griscelli; Paule Opolon; Jeannette Soria; Patrice Yeh; Chantal Legrand; Jean Pierre Vannier; Dominique Belin; Michel Perricaudet; He Lu
Amino-terminal fragment of urokinase inhibits tumor cell invasion in vitro and in vivo: respective contribution of the urokinase plasminogen activator receptor-dependent or -independent pathway.
Human gene therapy 2005;16(10):1157-67.
2005: Sonia Lavisse; Angelo Paci; Valérie Rouffiac; Cecile Adotevi; Paule Opolon; Pierre Peronneau; Philippe Bourget; Alain Roche; Michel Perricaudet; Elias Fattal; Nathalie Lassau
In vitro echogenicity characterization of poly[lactide-coglycolide] (plga) microparticles and preliminary in vivo ultrasound enhancement study for ultrasound contrast agent application.
Investigative radiology 2005;40(8):536-44.
2005: Claire Magnon; Ariane Galaup; Brian Mullan; Valérie Rouffiac; Céline Bouquet; Jean-Michel Bidart; Frank Griscelli; Paule Opolon; Michel Perricaudet
Canstatin acts on endothelial and tumor cells via mitochondrial damage initiated through interaction with alphavbeta3 and alphavbeta5 integrins.
Cancer research 2005;65(10):4353-61.
2005: Ariane Galaup; Claire Magnon; Valérie Rouffiac; Paule Opolon; David Opolon; Nathalie Lassau; Thomas Tursz; Michel Perricaudet; Frank Griscelli
Full kringles of plasminogen (aa 1-566) mediate complete regression of human MDA-MB-231 breast tumor xenografted in nude mice.
Gene therapy 2005;12(10):831-42.
2004: Jamila Faivre; Jérôme Clerc; René Gérolami; Julie Hervé; Michèle Longuet; Bingkai Liu; Jérôme Roux; Frédéric Moal; Michel Perricaudet; Christian Bréchot
Long-term radioiodine retention and regression of liver cancer after sodium iodide symporter gene transfer in wistar rats.
Cancer research 2004;64(21):8045-51.
2004: B Mullan; C Dugué; V Moutard; D Raoux; G Tremp; Patrice DENEFLE; Michel Perricaudet; jean-jacques robert
Robust functional gene validation by adenoviral vectors: one-step Escherichia coli-derived recombinant adenoviral genome construction.
Gene therapy 2004;11(21):1599-605.
2004: Valérie Rouffiac; Céline Bouquet; Nathalie Lassau; Paule Opolon; serge koscielny; Pierre Peronneau; Michel Perricaudet; Alain Roche
Validation of a new method for quantifying in vivo murine tumor necrosis by sonography.
Investigative radiology 2004;39(6):350-6.
2004: Véronique Trochon-Joseph; Dominique Martel-Renoir; Lluis M Mir; Annick Thomaïdis; Paule Opolon; Elisabeth Connault; Hong Li; Christophe Grenet; Françoise Fauvel-Lafève; Jeannette Soria; Chantal Legrand; Claudine Soria; Michel Perricaudet; He Lu
Evidence of antiangiogenic and antimetastatic activities of the recombinant disintegrin domain of metargidin.
Cancer research 2004;64(6):2062-9.
2004: Danièle Noël; Dan Gazit; Céline Bouquet; Florence Apparailly; Claire Bony; Pascale Plence; Virginie Millet; Gadi Turgeman; Michel Perricaudet; Jacques Sany; Christian Jorgensen
Short-term BMP-2 expression is sufficient for in vivo osteochondral differentiation of mesenchymal stem cells.
Stem cells (Dayton, Ohio) 2004;22(1):74-85.
2003: Laurence Le Gat; Karïn Gogat; Céline Bouquet; magali Saint-Geniez; Diane C Darland; Loïc Van Den Berghe; Dominique Marchant; Alexandra C Provost; Michel Perricaudet; Maurice Menasche; marc Mordekhaï ABITBOL
In vivo adenovirus-mediated delivery of a uPA/uPAR antagonist reduces retinal neovascularization in a mouse model of retinopathy.
Gene therapy 2003;10(25):2098-103.
2003: Loïc de Pontual; Virginie Népote; Tania Attié-Bitach; Hassan Al Halabiah; Ha Trang; Vincent Elghouzzi; Béatrice Levacher; Karim Benihoud; Joëlle Augé; Christophe Faure; Béatrice Laudier; Michel Vekemans; Arnold Munnich; Michel Perricaudet; François Guillemot; Claude Gaultier; Stanislas LYONNET; Michel Simonneau; Jeanne Amiel
Noradrenergic neuronal development is impaired by mutation of the proneural HASH-1 gene in congenital central hypoventilation syndrome (Ondine's curse).
Human molecular genetics 2003;12(23):3173-80.
2003: Jean-Marc Joseph; Céline Bouquet; Paule Opolon; Jackie Morizet; Geneviève Aubert; Jochen Rössler; Nicole Gross; Frank Griscelli; Michel Perricaudet; Gilles Vassal
High level of stabilized angiostatin mediated by adenovirus delivery does not impair the growth of human neuroblastoma xenografts.
Cancer gene therapy 2003;10(11):859-66.
2003: Marie-Aude Pascaud; Frank Griscelli; william raoul; Elisabeth Marcos; Paule Opolon; Bernadette Raffestin; Michel Perricaudet; Serge Adnot; Saadia Eddahibi
Lung overexpression of angiostatin aggravates pulmonary hypertension in chronically hypoxic mice.
American journal of respiratory cell and molecular biology 2003;29(4):449-57.
2003: Etienne Thévenot; Francine Côté; Philippe Colin; Yi He; Hélène Leblois; Michel Perricaudet; Jacques Mallet; Guilan Vodjdani
Targeting conditional gene modification into the serotonin neurons of the dorsal raphe nucleus by viral delivery of the Cre recombinase.
Molecular and cellular neurosciences 2003;24(1):139-47.
2003: Karine Martin; Anne Brie; Patrick Saulnier; Michel Perricaudet; Patrice Yeh; Emmanuelle Vigne
Simultaneous CAR- and alpha V integrin-binding ablation fails to reduce Ad5 liver tropism.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(3):485-94.
2003: Dominique Martel-Renoir; Véronique Trochon-Joseph; Ariane Galaup; Céline Bouquet; Frank Griscelli; Paule Opolon; David Opolon; Elisabeth Connault; Lluis M Mir; Michel Perricaudet
Coelectrotransfer to skeletal muscle of three plasmids coding for antiangiogenic factors and regulatory factors of the tetracycline-inducible system: tightly regulated expression, inhibition of transplanted tumor growth, and antimetastatic effect.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(3):425-33.
2003: Fatima Dkhissi; He Lu; Claudine Soria; Paule Opolon; Frank Griscelli; Hanfeng Liu; Patricia Khattar; Zohar Mishal; Michel Perricaudet; Hong Li
Endostatin exhibits a direct antitumor effect in addition to its antiangiogenic activity in colon cancer cells.
Human gene therapy 2003;14(10):997-1008.
2003: Nicolas Foray; Didier Marot; Anastasia Gabriel; Voahangy Randrianarison; Antony M Carr; Michel Perricaudet; Alan Ashworth; Penny A Jeggo
A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein.
The EMBO journal 2003;22(11):2860-71.
2003: Ariane Galaup; Paule Opolon; Céline Bouquet; Hong Li; David Opolon; Marie-Christine Bissery; Thomas Tursz; Michel Perricaudet; Frank Griscelli
Combined effects of docetaxel and angiostatin gene therapy in prostate tumor model.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(6):731-40.
2003: Céline Bouquet; Eric Frau; Paule Opolon; Elisabeth Connault; marc Mordekhaï ABITBOL; Frank Griscelli; Patrice Yeh; Michel Perricaudet
Systemic administration of a recombinant adenovirus encoding a HSA-Angiostatin kringle 1-3 conjugate inhibits MDA-MB-231 tumor growth and metastasis in a transgenic model of spontaneous eye cancer.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(2):174-84.
2003: Frank Griscelli; Emre Belli; Paule Opolon; Karine Musset; Elisabeth Connault; Michel Perricaudet; Alain Serraf; Guy-Michel Mazmanian; Thierry Ragot
Adenovirus-mediated gene transfer to the transplanted piglet heart after intracoronary injection.
The journal of gene medicine 2003;5(2):109-19.
2003: Emmanuelle Vigne; Jean-François Dedieu; Anne Brie; A Gillardeaux; Delphine Briot; Karim Benihoud; Martine Latta-Mahieu; Patrick Saulnier; Michel Perricaudet; Patrice Yeh
Genetic manipulations of adenovirus type 5 fiber resulting in liver tropism attenuation.
Gene therapy 2003;10(2):153-62.
2002: Nicolas Foray; Didier Marot; Voahangy Randrianarison; Nicole Dalla Venezia; Didier Picard; Michel Perricaudet; Vincent Favaudon; Penny A Jeggo
Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation.
Molecular and cellular biology 2002;22(12):4020-32.
2002: Michel Kalamarides; Michiko Niwa-Kawakita; Hélène Leblois; Vincent Abramowski; Michel Perricaudet; Anne Janin; Gilles Thomas; David H Gutmann; Marco Giovannini
Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse.
Genes & development 2002;16(9):1060-5.
2002: Florence Apparailly; Céline Bouquet; Virginie Millet; Danielle Noel; Chantal Jacquet; Paule Opolon; Michel Perricaudet; Jacques Sany; Patrice Yeh; Christian Jorgensen
Adenovirus-mediated gene transfer of urokinase plasminogen inhibitor inhibits angiogenesis in experimental arthritis.
Gene therapy 2002;9(3):192-200.
2002: Anne Boland; Claire Magnon; Sebastiano Filetti; Jean-Michel Bidart; Martin Schlumberger; Patrice Yeh; Michel Perricaudet
Transposition of the thyroid iodide uptake and organification system in nonthyroid tumor cells by adenoviral vector-mediated gene transfers.
Thyroid : official journal of the American Thyroid Association 2002;12(1):19-26.
2001: jean-jacques robert; I Gauffeny; Jean Maccario; C Jullien; Pierre Benoit; Emmanuelle Vigne; Joël J Crouzet; Michel Perricaudet; Patrice Yeh
Degenerated pIX-IVa2 adenoviral vector sequences lowers reacquisition of the E1 genes during virus amplification in 293 cells.
Gene therapy 2001;8(22):1713-20.
2001: Voahangy Randrianarison; Didier Marot; Nicolas Foray; J Cabannes; V Méret; Elisabeth Connault; N Vitrat; Paule Opolon; Michel Perricaudet; Jean Feunteun
BRCA1 carries tumor suppressor activity distinct from that of p53 and p21.
Cancer gene therapy 2001;8(10):759-70.
2001: M Andrawiss; Anne Maron; W Beltran; Paule Opolon; Elisabeth Connault; Frank Griscelli; Patrice Yeh; Michel Perricaudet; P Devauchelle
Adenovirus-mediated gene transfer in canine eyes: a preclinical study for gene therapy of human uveal melanoma.
The journal of gene medicine 2001;3(3):228-39.
2001: Amin Hajitou; Nor Eddine SOUNNI; Laetitia Devy; Christine Grignet-Debrus; Jean-Marc Lewalle; H Li; Christophe Deroanne; H Lu; Alain Colige; Betty Nusgens; Francis Frankenne; Anne Maron; Patrice Yeh; Michel Perricaudet; Y Chang; Claudine Soria; CM Calberg-Bacq; Jean-Michel Foidart; Agnès Noël
Down-regulation of vascular endothelial growth factor by tissue inhibitor of metalloproteinase-2: effect on in vivo mammary tumor growth and angiogenesis.
Cancer research 2001;61(8):3450-7.
2001: Hong Li; Frederique Lindenmeyer; Christophe Grenet; Paule Opolon; Suzanne Menashi; Claudine Soria; Patrice Yeh; Michel Perricaudet; He Lu
AdTIMP-2 inhibits tumor growth, angiogenesis, and metastasis, and prolongs survival in mice.
Human gene therapy 2001;12(5):515-26.
2001: N Chossat; Frank Griscelli; P Jourdon; Damien Logeart; Thierry Ragot; Michèle Heimburger; Michel Perricaudet; Anne-Marie Lompré; Stéphane N Hatem; Jean-Jacques Mercadier
Adenoviral SERCA1a gene transfer to adult rat ventricular myocytes induces physiological changes in calcium handling.
Cardiovascular research 2001;49(2):288-97.
2001: Aline Van Pel; Etienne De Plaen; Marie-Thérèse Duffour; Guy Warnier; Catherine Uyttenhove; Michel Perricaudet; Thierry Boon
Induction of cytolytic T lymphocytes by immunization of mice with an adenovirus containing a mouse homolog of the human MAGE-A genes.
Cancer immunology, immunotherapy : CII 2001;49(11):593-602.
2000: F Le Page; Voahangy Randrianarison; Didier Marot; J Cabannes; Michel Perricaudet; Jean Feunteun; Alain Sarasin
BRCA1 and BRCA2 are necessary for the transcription-coupled repair of the oxidative 8-oxoguanine lesion in human cells.
Cancer research 2000;60(19):5548-52.
2000: C Torrent; C Jullien; David Klatzmann; Michel Perricaudet; Patrice Yeh
Transgene amplification and persistence after delivery of retroviral vector and packaging functions with E1/E4-deleted adenoviruses.
Cancer gene therapy 2000;7(8):1135-44.
2000: A Boland; M Ricard; Paule Opolon; Jean-Michel Bidart; Patrice Yeh; Sebastiano Filetti; Martin Schlumberger; Michel Perricaudet
Adenovirus-mediated transfer of the thyroid sodium/iodide symporter gene into tumors for a targeted radiotherapy.
Cancer research 2000;60(13):3484-92.
2000: Frank Griscelli; Hong Li; C Cheong; Paule Opolon; Annelise Bennaceur-Griscelli; Gilles Vassal; Jeannette Soria; Claudine Soria; He Lu; Michel Perricaudet; Patrice Yeh
Combined effects of radiotherapy and angiostatin gene therapy in glioma tumor model.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6698-703.
2000: Karim Benihoud; Barbara Salone; Stéphanie Esselin; Paule Opolon; V Poli; Monica Di Giovine; Michel Perricaudet; Isabella Saggio
The role of IL-6 in the inflammatory and humoral response to adenoviral vectors.
The journal of gene medicine 2000;2(3):194-203.
2000: Damien Logeart; Stéphane N Hatem; Catherine Rücker-Martin; N Chossat; N Névo; Hedi Haddada; Michèle Heimburger; Michel Perricaudet; Jean-Jacques Mercadier
Highly efficient adenovirus-mediated gene transfer to cardiac myocytes after single-pass coronary delivery.
Human gene therapy 2000;11(7):1015-22.
2000: Hélène Leblois; C Roche; N Di Falco; C Orsini; Patrice Yeh; Michel Perricaudet
Stable transduction of actively dividing cells via a novel adenoviral/episomal vector.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(4):314-22.
1999: Hong Li; Frank Griscelli; Frederique Lindenmeyer; Paule Opolon; L Q Sun; Elisabeth Connault; Jeannette Soria; Claudine Soria; Michel Perricaudet; Patrice Yeh; He Lu
Systemic delivery of antiangiogenic adenovirus AdmATF induces liver resistance to metastasis and prolongs survival of mice.
Human gene therapy 1999;10(18):3045-53.
1999: Nicolas Foray; Voahangy Randrianarison; Didier Marot; Michel Perricaudet; Gilbert Lenoir; Jean Feunteun
Gamma-rays-induced death of human cells carrying mutations of BRCA1 or BRCA2.
Oncogene 1999;18(51):7334-42.
1999: Karim Benihoud; Patrice Yeh; Michel Perricaudet
Adenovirus vectors for gene delivery.
Current opinion in biotechnology 1999;10(5):440-7.
1999: C Garcia-Martinez; Paule Opolon; V Trochon; C Chianale; K Musset; He Lu; M Abitbol; Michel Perricaudet; Thierry Ragot
Angiogenesis induced in muscle by a recombinant adenovirus expressing functional isoforms of basic fibroblast growth factor.
Gene therapy 1999;6(7):1210-21.
1999: Emmanuelle Vigne; Irene Mahfouz; Jean-François Dedieu; Anne Brie; Michel Perricaudet; Patrice Yeh
RGD inclusion in the hexon monomer provides adenovirus type 5-based vectors with a fiber knob-independent pathway for infection.
Journal of virology 1999;73(6):5156-61.
1999: Nadine C Fernandez; A Lozier; Caroline Flament; Paola Ricciardi-Castagnoli; Dominique Bellet; M Suter; Michel Perricaudet; Thomas Tursz; E Maraskovsky; Laurence Zitvogel
Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo.
Nature medicine 1999;5(4):405-11.
1999: Nadine Fernandez; Jean-Pierre Levraud; Hedi Haddada; Michel Perricaudet; Philippe Kourilsky
High frequency of specific CD8+ T cells in the tumor and blood is associated with efficient local IL-12 gene therapy of cancer.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(1):609-17.
1998: Karim Benihoud; Isabella Saggio; Paule Opolon; Barbara Salone; F Amiot; Elisabeth Connault; C Chianale; François Dautry; Patrice Yeh; Michel Perricaudet
Efficient, repeated adenovirus-mediated gene transfer in mice lacking both tumor necrosis factor alpha and lymphotoxin alpha.
Journal of virology 1998;72(12):9514-25.
1998: Frank Griscelli; P Gilardi-Hebenstreit; N Hanania; W M Franz; Paule Opolon; Michel Perricaudet; Thierry Ragot
Heart-specific targeting of beta-galactosidase by the ventricle-specific cardiac myosin light chain 2 promoter using adenovirus vectors.
Human gene therapy 1998;9(13):1919-28.
1998: H Li; He Lu; Frank Griscelli; Paule Opolon; L Q Sun; Thierry Ragot; Y Legrand; D Belin; Jeannette Soria; Claudine Soria; Michel Perricaudet; Patrice Yeh
Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice.
Gene therapy 1998;5(8):1105-13.
1998: Frank Griscelli; Hong Li; Annelise Bennaceur-Griscelli; Jeannette Soria; Paule Opolon; Claudine Soria; Michel Perricaudet; Patrice Yeh; He Lu
Angiostatin gene transfer: inhibition of tumor growth in vivo by blockage of endothelial cell proliferation associated with a mitosis arrest.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6367-72.
1998: N Fernandez; Marie-Thérèse Duffour; Michel Perricaudet; M T Lotze; T Tursz; L Zitvogel
Active specific T-cell-based immunotherapy for cancer: nucleic acids, peptides, whole native proteins, recombinant viruses, with dendritic cell adjuvants or whole tumor cell-based vaccines. Principles and future prospects.
Cytokines, cellular & molecular therapy 1998;4(1):53-65.
1997: B Klonjkowski; P Gilardi-Hebenstreit; J Hadchouel; Voahangy Randrianarison; S Boutin; Patrice Yeh; Michel Perricaudet; Eric J Kremer
A recombinant E1-deleted canine adenoviral vector capable of transduction and expression of a transgene in human-derived cells and in vivo.
Human gene therapy 1997;8(17):2103-15.
1997: Isabella Saggio; Laura Ciapponi; Rocco Savino; Gennaro Ciliberto; Michel Perricaudet
Adenovirus-mediated gene transfer of a human IL-6 antagonist.
Gene therapy 1997;4(8):839-45.
1997: Philippe Gabriel STEG; O Tahlil; N Aubailly; Jean-Michel Caillaud; Jean-François Dedieu; K Berthelot; Aude Le-Roux; L Feldman; Michel Perricaudet; Patrice DENEFLE; Didier Branellec
Reduction of restenosis after angioplasty in an atheromatous rabbit model by suicide gene therapy.
Circulation 1997;96(2):408-11.
1997: Patrice Yeh; Michel Perricaudet
Advances in adenoviral vectors: from genetic engineering to their biology.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(8):615-23.
1997: Nicole Chenciner; V Randrianarison-Jewtoukoff; Francis Delpeyroux; N Hanania; L Pedroza Martins; L Stratford Perricaudet; Michel Perricaudet; Simon Wain-Hobson
Enhancement of humoral immunity to SIVenv following simultaneous inoculation of mice by three recombinant adenoviruses encoding SIVenv/poliovirus chimeras, Tat and Rev.
AIDS research and human retroviruses 1997;13(9):801-6.
1997: Jean-François Dedieu; Emmanuelle Vigne; C Torrent; C Jullien; Irene Mahfouz; Jean-Michel Caillaud; N Aubailly; C Orsini; J M Guillaume; Paule Opolon; P Delaere; Michel Perricaudet; Patrice Yeh
Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses.
Journal of virology 1997;71(6):4626-37.
1997: Jean-Pierre Levraud; Marie-Thérèse Duffour; L Cordier; Michel Perricaudet; Hedi Haddada; Philippe Kourilsky
IL-2 gene delivery within an established murine tumor causes its regression without proliferation of preexisting antitumor-specific CTL.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3335-43.
1997: L J Feldman; C J Pastore; N Aubailly; Marianne Kearney; D Chen; Michel Perricaudet; Philippe Gabriel STEG; Jeffrey M Isner
Improved efficiency of arterial gene transfer by use of poloxamer 407 as a vehicle for adenoviral vectors.
Gene therapy 1997;4(3):189-98.
1997: Joël J Crouzet; L Naudin; C Orsini; Emmanuelle Vigne; L Ferrero; Aude Le-Roux; Pierre Benoit; M Latta; C Torrent; Didier Branellec; Patrice DENEFLE; JF Mayaux; Michel Perricaudet; Patrice Yeh
Recombinational construction in Escherichia coli of infectious adenoviral genomes.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1414-9.
1997: Phuong-Lan Tran; J Weinbach; Paule Opolon; G Linares-Cruz; J P Reynes; A Grégoire; Eric J Kremer; H Durand; Michel Perricaudet
Prevention of bleomycin-induced pulmonary fibrosis after adenovirus-mediated transfer of the bacterial bleomycin resistance gene.
The Journal of clinical investigation 1997;99(4):608-17.
1997: Frank Griscelli; Paule Opolon; C Chianale; N Di Falco; W M Franz; Michel Perricaudet; Thierry Ragot
Expression from cardiomyocyte-specific promoter after adenovirus-mediated gene transfer in vitro and in vivo.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1997;320(2):103-12.
1997: Thierry Ragot; Paule Opolon; Michel Perricaudet
Adenoviral gene delivery.
Methods in cell biology 1997;52():229-60.
1997: Anne Maron; N Havaux; Aude Le-Roux; B Knoops; Michel Perricaudet; Jean-Noël Octave
Differential toxicity of ganciclovir for rat neurons and astrocytes in primary culture following adenovirus-mediated transfer of the HSVtk gene.
Gene therapy 1997;4(1):25-31.
1996: T Tursz; A L Cesne; P Baldeyrou; E Gautier; Paule Opolon; C Schatz; A Pavirani; M Courtney; D Lamy; Thierry Ragot; P Saulnier; Antoine Andremont; Roger Monier; Michel Perricaudet; Thierry Le Chevalier
Phase I study of a recombinant adenovirus-mediated gene transfer in lung cancer patients.
Journal of the National Cancer Institute 1996;88(24):1857-63.
1996: E J Kremer; N D Di Falco; Paule Opolon; Michel Perricaudet
Adenovirus vector-transduced hepatocytes implanted via a preformed collagen/PTFE support persist for at least 4 weeks in vivo.
Gene therapy 1996;3(10):932-6.
1996: V Descamps; N Blumenfeld; Y Beuzard; Michel Perricaudet
Keratinocytes as a target for gene therapy. Sustained production of erythropoietin in mice by human keratinocytes transduced with an adenoassociated virus vector.
Archives of dermatology 1996;132(10):1207-11.
1996: S Akli; Jacques-Emmanuel Guidotti; Emmanuelle Vigne; Michel Perricaudet; K Sandhoff; Axel Kahn; Livia Poenaru
Restoration of hexosaminidase A activity in human Tay-Sachs fibroblasts via adenoviral vector-mediated gene transfer.
Gene therapy 1996;3(9):769-74.
1996: P B Arbuthnot; M P Bralet; C Le Jossic; J F Dedieu; Michel Perricaudet; Christian Bréchot; Nicolas Ferry
In vitro and in vivo hepatoma cell-specific expression of a gene transferred with an adenoviral vector.
Human gene therapy 1996;7(13):1503-14.
1996: Guy Warnier; Marie-Thérèse Duffour; Catherine Uyttenhove; Thomas F Gajewski; Christophe Lurquin; Hedi Haddada; Michel Perricaudet; Thierry Boon
Induction of a cytolytic T-cell response in mice with a recombinant adenovirus coding for tumor antigen P815A.
International journal of cancer. Journal international du cancer 1996;67(2):303-10.
1996: V Descamps; Marie-Thérèse Duffour; Marie-Christine Mathieu; N Fernandez; L Cordier; Mohamed Amine Abina; E Kremer; Michel Perricaudet; Hedi Haddada
Strategies for cancer gene therapy using adenoviral vectors.
Journal of molecular medicine (Berlin, Germany) 1996;74(4):183-9.
1996: Anne Maron; T Gustin; Aude Le-Roux; I Mottet; Jean-François Dedieu; Jean-Pierre Brion; Roger J Demeure; Michel Perricaudet; Jean-Noël Octave
Gene therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene: long-term follow-up by magnetic resonance imaging.
Gene therapy 1996;3(4):315-22.
1996: Mohamed Amine Abina; M G Lee; V Descamps; L Cordier; M Lopez; Michel Perricaudet; Hedi Haddada
LacZ gene transfer into tumor cells abrogates tumorigenicity and protects mice against the development of further tumors.
Gene therapy 1996;3(3):212-6.
1996: Thierry Ragot; Michel Perricaudet
[Development of adenoviral vectors in gene therapy: application to gene transfer in muscles].
Comptes rendus des séances de la Société de biologie et de ses filiales 1996;190(1):13-31.
1996: Patrice Yeh; Jean-François Dedieu; C Orsini; Emmanuelle Vigne; Patrice DENEFLE; Michel Perricaudet
Efficient dual transcomplementation of adenovirus E1 and E4 regions from a 293-derived cell line expressing a minimal E4 functional unit.
Journal of virology 1996;70(1):559-65.
1995: Martine Mergey; M Lemnaouar; D Veissiere; Michel Perricaudet; Dieter C Gruenert; J Picard; Jacqueline Capeau; Marie Christiane Brahimi-Horn; Annick Paul
CFTR gene transfer corrects defective glycoconjugate secretion in human CF epithelial tracheal cells.
The American journal of physiology 1995;269(6 Pt 1):L855-64.
1995: V Descamps; N Blumenfeld; Michel Perricaudet; Y Beuzard; E J Kremer
Organoids direct systemic expression of erythropoietin in mice.
Gene therapy 1995;2(6):411-7.
1995: L J Feldman; Philippe Gabriel STEG; L P Zheng; D Chen; Marianne Kearney; S E McGarr; J J Barry; J F Dedieu; Michel Perricaudet; Jeffrey M Isner
Low-efficiency of percutaneous adenovirus-mediated arterial gene transfer in the atherosclerotic rabbit.
The Journal of clinical investigation 1995;95(6):2662-71.
1995: M G Lee; Mohamed Amine Abina; Hedi Haddada; Michel Perricaudet
The constitutive expression of the immunomodulatory gp19k protein in E1-, E3- adenoviral vectors strongly reduces the host cytotoxic T cell response against the vector.
Gene therapy 1995;2(4):256-62.
1995: N Chenciner; L Pedroza Martins; N Hanania; L Stratford Perricaudet; Michel Perricaudet; Simon Wain-Hobson
Residual expression of reporter genes in constructs mimicking HIV genome organization.
Research in virology 1995;146(3):171-8.
1995: Emmanuelle Vigne; Jean-François Dedieu; C Orsini; P Denèfle; Michel Perricaudet; Patrice Yeh
Third-generation adenovectors for gene therapy.
Restorative neurology and neuroscience 1995;8(1):35-6.
1995: E J Kremer; Michel Perricaudet
Adenovirus and adeno-associated virus mediated gene transfer.
British medical bulletin 1995;51(1):31-44.
1995: L Cordier; Marie-Thérèse Duffour; Jean-Christophe Sabourin; M G Lee; J Cabannes; Thierry Ragot; Michel Perricaudet; Hedi Haddada
Complete recovery of mice from a pre-established tumor by direct intratumoral delivery of an adenovirus vector harboring the murine IL-2 gene.
Gene therapy 1995;2(1):16-21.
1995: Hedi Haddada; L Cordier; Michel Perricaudet
Gene therapy using adenovirus vectors.
Current topics in microbiology and immunology 1995;199 ( Pt 3)():297-306.
1994: Aude Le-Roux; B Kerdiles; D Walls; Jean-François Dedieu; Michel Perricaudet
The Epstein-Barr virus determined nuclear antigens EBNA-3A, -3B, and -3C repress EBNA-2-mediated transactivation of the viral terminal protein 1 gene promoter.
Virology 1994;205(2):596-602.
1994: Philippe Gabriel STEG; L J Feldman; J Y Scoazec; O Tahlil; J J Barry; S Boulechfar; T Ragot; J M Isner; Michel Perricaudet
Arterial gene transfer to rabbit endothelial and smooth muscle cells using percutaneous delivery of an adenoviral vector.
Circulation 1994;90(4):1648-56.
1994: V Descamps; N Blumenfeld; Jean-Luc Villeval; William Vainchenker; Michel Perricaudet; Y Beuzard
Erythropoietin gene transfer and expression in adult normal mice: use of an adenovirus vector.
Human gene therapy 1994;5(8):979-85.
1994: Philippe Moullier; G Friedlander; D Calise; Pierre Ronco; Michel Perricaudet; Nicolas Ferry
Adenoviral-mediated gene transfer to renal tubular cells in vivo.
Kidney international 1994;45(4):1220-5.
1993: Hedi Haddada; Thierry Ragot; L Cordier; Marie-Thérèse Duffour; Michel Perricaudet
Adenoviral interleukin-2 gene transfer into P815 tumor cells abrogates tumorigenicity and induces antitumoral immunity in mice.
Human gene therapy 1993;4(6):703-11.
1993: Catherine Caillaud; S Akli; Emmanuelle Vigne; Annette Koulakoff; Michel Perricaudet; Livia Poenaru; Axel Kahn; Y Berwald-Netter
Adenoviral vector as a gene delivery system into cultured rat neuronal and glial cells.
The European journal of neuroscience 1993;5(10):1287-91.
1993: N Vincent; Thierry Ragot; H Gilgenkrantz; D Couton; P Chafey; A Grégoire; Pascale Briand; Jean-Claude Kaplan; Axel Kahn; Michel Perricaudet
Long-term correction of mouse dystrophic degeneration by adenovirus-mediated transfer of a minidystrophin gene.
Nature genetics 1993;5(2):130-4.
1993: Hedi Haddada; M Lopez; C Martinache; Thierry Ragot; Mohamed Amine Abina; Michel Perricaudet
Efficient adenovirus-mediated gene transfer into human blood monocyte-derived macrophages.
Biochemical and biophysical research communications 1993;195(3):1174-83.
1993: S Akli; Catherine Caillaud; Emmanuelle Vigne; L D Stratford-Perricaudet; Livia Poenaru; Michel Perricaudet; Axel Kahn; Marc Peschanski
Transfer of a foreign gene into the brain using adenovirus vectors.
Nature genetics 1993;3(3):224-8.
1993: Thierry Ragot; S Finerty; PE Watkins; Michel Perricaudet; Andrew J Morgan
Replication-defective recombinant adenovirus expressing the Epstein-Barr virus (EBV) envelope glycoprotein gp340/220 induces protective immunity against EBV-induced lymphomas in the cottontop tamarin.
The Journal of general virology 1993;74 ( Pt 3)():501-7.
1993: Aude Le-Roux; M Berebbi; M Moukaddem; Michel Perricaudet; Irene Joab
Identification of a short amino acid sequence essential for efficient nuclear targeting of the Epstein-Barr virus nuclear antigen 3A.
Journal of virology 1993;67(3):1716-20.
1993: Thierry Ragot; N Vincent; P Chafey; Emmanuelle Vigne; H Gilgenkrantz; D Couton; J Cartaud; Pascale Briand; Jean-Claude Kaplan; Michel Perricaudet
Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice.
Nature 1993;361(6413):647-50.
1992: B Klonjkowski; D Walls; P Gilardi-Hebenstreit; Michel Perricaudet
Repression of the viral latent promoter BC-R2 in Epstein-Barr virus negative cell lines.
Biochemical and biophysical research communications 1992;189(3):1695-700.
1992: L D Stratford-Perricaudet; I Makeh; Michel Perricaudet; Pascale Briand
Widespread long-term gene transfer to mouse skeletal muscles and heart.
The Journal of clinical investigation 1992;90(2):626-30.
1992: L D Stratford-Perricaudet; Pascale Briand; Michel Perricaudet
Feasibility of adenovirus-mediated gene transfer in vivo.
Bone marrow transplantation 1992;9 Suppl 1():151-2.
1991: Irene Joab; J C Nicolas; G Schwaab; Guy de Thé; Bernard Clausse; Michel Perricaudet; Y Zeng
Detection of anti-Epstein-Barr-virus transactivator (ZEBRA) antibodies in sera from patients with nasopharyngeal carcinoma.
International journal of cancer. Journal international du cancer 1991;48(5):647-9.
1991: Massimo Levrero; V Barban; S Manteca; A Ballay; C Balsamo; Maria Laura Avantaggiati; Gioacchino Natoli; H Skellekens; P Tiollais; Michel Perricaudet
Defective and nondefective adenovirus vectors for expressing foreign genes in vitro and in vivo.
Gene 1991;101(2):195-202.
1991: Clara Balsano; Maria Laura Avantaggiati; Gioacchino Natoli; E De Marzio; H Will; Michel Perricaudet; Massimo Levrero
Full-length and truncated versions of the hepatitis B virus (HBV) X protein (pX) transactivate the cmyc protooncogene at the transcriptional level.
Biochemical and biophysical research communications 1991;176(3):985-92.
1991: D Walls; Michel Perricaudet
The identification of new transcription elements active in Epstein-Barr virus latent gene expression.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1991;312(3):85-90.
1991: D Walls; Michel Perricaudet
Novel downstream elements upregulate transcription initiated from an Epstein-Barr virus latent promoter.
The EMBO journal 1991;10(1):143-51.
1991: Irene Joab; H Triki; J de Saint Martin; Michel Perricaudet; J C Nicolas
Detection of anti-Epstein-Barr virus trans-activator (ZEBRA) antibodies in sera from patients with human immunodeficiency virus.
The Journal of infectious diseases 1991;163(1):53-6.
1990: P Gilardi; M Courtney; A Pavirani; Michel Perricaudet
Expression of human alpha 1-antitrypsin using a recombinant adenovirus vector.
FEBS letters 1990;267(1):60-2.
1990: B Kerdiles; D Walls; H Triki; Michel Perricaudet; Irene Joab
cDNA cloning and transient expression of the Epstein-Barr virus-determined nuclear antigen EBNA3B in human cells and identification of novel transcripts from its coding region.
Journal of virology 1990;64(4):1812-6.
1990: L D Stratford-Perricaudet; Massimo Levrero; J F Chasse; Michel Perricaudet; Pascale Briand
Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector.
Human gene therapy 1990;1(3):241-56.
1989: P Gilardi; L Stratford; J M Egly; Michel Perricaudet
The two core sequences of the adenovirus E1A inducible E4 promoter are required for the formation of a specific DNA-protein complex.
Biochemical and biophysical research communications 1989;163(2):1143-9.
1989: E Tosoni-Pittoni; Irene Joab; J C Nicolas; Michel Perricaudet
Complete characterization of the gene coding for the Epstein-Barr virus major membrane antigen gp 220/340 and selective expression of a secreted form of gp 220.
Biochemical and biophysical research communications 1989;158(3):676-84.

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