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Yuri Persidsky
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43
Gendelman, Howard
19
Ghorpade, Anuja
12
Haorah, James
11
Zheng, Jialin
10
Limoges, Jenae
9
Heilman, David
9
Ramirez, Servio
8
Poluektova, Larisa
8
Xiong, Huangui
7
Knipe, Bryan
6
Bock, P
6
Che, MH
6
Potula, Raghava
5
Rasmussen, Jennifer
5
Swindells, Susan
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All Publications
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2009: Xiong Wanfen; MacTaggart Jason; Knispel Rebecca; Worth Jennifer; Persidsky Yuri; Baxter B Timothy
Blocking TNF-alpha attenuates aneurysm formation in a murine model.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2741-6.
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2009: Gendelman Howard E; Ding Shengyuan; Gong Nan; Liu Jianuo; Ramirez Servio H; Persidsky Yuri; Mosley R Lee; Wang Tong; Volsky David J; Xiong Huangui
Monocyte chemotactic protein-1 regulates voltage-gated K+ channels and macrophage transmigration.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2009;4(1):47-59.
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2008: Haorah James; Ramirez Servio H; Floreani Nicholas; Gorantla Santhi; Morsey Brenda; Persidsky Yuri
Mechanism of alcohol-induced oxidative stress and neuronal injury.
Free radical biology & medicine 2008;45(11):1542-50.
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2008: Ronaldson Patrick T; Persidsky Yuri; Bendayan Reina
Regulation of ABC membrane transporters in glial cells: relevance to the pharmacotherapy of brain HIV-1 infection.
Glia 2008;56(16):1711-35.
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2008: Potula Raghava; Ramirez Servio H; Knipe Bryan; Leibhart Jessica; Schall Kathy; Heilman David; Morsey Brenda; Mercer Aaron; Papugani Anil; Dou Huanyu; Persidsky Yuri
Peroxisome proliferator-activated receptor-gamma activation suppresses HIV-1 replication in an animal model of encephalitis.
AIDS (London, England) 2008;22(13):1539-49.
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2008: Potula Raghava; Persidsky Yuri
Adding fuel to the fire: methamphetamine enhances HIV infection.
The American journal of pathology 2008;172(6):1467-70.
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2008: Chaudhuri Anathbandhu; Duan Fenghai; Morsey Brenda; Persidsky Yuri; Kanmogne Georgette D
HIV-1 activates proinflammatory and interferon-inducible genes in human brain microvascular endothelial cells: putative mechanisms of blood-brain barrier dysfunction.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(4):697-711.
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2008: Ramirez Servio H; Heilman David; Morsey Brenda; Potula Raghava; Haorah James; Persidsky Yuri
Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses Rho GTPases in human brain microvascular endothelial cells and inhibits adhesion and transendothelial migration of HIV-1 infected monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(3):1854-65.
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2008: Yamamoto Masaru; Ramirez Servio H; Sato Shinji; Kiyota Tomomi; Cerny Ronald L; Kaibuchi Kozo; Persidsky Yuri; Ikezu Tsuneya
Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells.
The American journal of pathology 2008;172(2):521-33.
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2008: Chaudhuri Anathbandhu; Yang Bo; Gendelman Howard E; Persidsky Yuri; Kanmogne Georgette D
STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier.
Blood 2008;111(4):2062-72.
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2008: Haorah James; Schall Kathy; Ramirez Servio H; Persidsky Yuri
Activation of protein tyrosine kinases and matrix metalloproteinases causes blood-brain barrier injury: Novel mechanism for neurodegeneration associated with alcohol abuse.
Glia 2008;56(1):78-88.
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2007: Liu Jianuo; Johnson Thomas V; Lin Jamie; Ramirez Servio H; Bronich Tatiana K; Caplan Steve; Persidsky Yuri; Gendelman Howard E; Kipnis Jonathan
T cell independent mechanism for copolymer-1-induced neuroprotection.
European journal of immunology 2007;37(11):3143-54.
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2007: Persidsky Yuri; Fox Howard
Battle of animal models.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2007;2(2):171-7.
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2007: Spitzenberger Timothy J; Heilman David; Diekmann Casey; Batrakova Elena V; Kabanov Alexander V; Gendelman Howard E; Elmquist William F; Persidsky Yuri
Novel delivery system enhances efficacy of antiretroviral therapy in animal model for HIV-1 encephalitis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(5):1033-42.
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2007: Ricardo-Dukelow Mary; Kadiu Irena; Rozek Wojciech; Schlautman Joshua; Persidsky Yuri; Ciborowski Pawel; Kanmogne Georgette D; Gendelman Howard E
HIV-1 infected monocyte-derived macrophages affect the human brain microvascular endothelial cell proteome: new insights into blood-brain barrier dysfunction for HIV-1-associated dementia.
Journal of neuroimmunology 2007;185(1-2):37-46.
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2007: Haorah James; Ramirez Servio H; Schall Kathy; Smith Daniel; Pandya Rita; Persidsky Yuri
Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction.
Journal of neurochemistry 2007;101(2):566-76.
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2007: Hauser Kurt F; El-Hage Nazira; Stiene-Martin Anne; Maragos William F; Nath Avindra; Persidsky Yuri; Volsky David J; Knapp Pamela E
HIV-1 neuropathogenesis: glial mechanisms revealed through substance abuse.
Journal of neurochemistry 2007;100(3):567-86.
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2007: Haorah James; Knipe Bryan; Gorantla Santhi; Zheng Jialin; Persidsky Yuri
Alcohol-induced blood-brain barrier dysfunction is mediated via inositol 1,4,5-triphosphate receptor (IP3R)-gated intracellular calcium release.
Journal of neurochemistry 2007;100(2):324-36.
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2007: Kanmogne Georgette D; Schall Kathy; Leibhart Jessica; Knipe Bryan; Gendelman Howard E; Persidsky Yuri
HIV-1 gp120 compromises blood-brain barrier integrity and enhances monocyte migration across blood-brain barrier: implication for viral neuropathogenesis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(1):123-34.
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2006: Berman Joan W; Carson Monica J; Chang Linda; Cox Brian M; Fox Howard S; Gonzalez R Gilberto; Hanson Glen R; Hauser Kurt F; Ho Wen-Zhe; Hong Jau-Shyong; Major Eugene O; Maragos William F; Masliah Eliezer; McArthur Justin C; Miller Diane B; Nath Avindra; O'Callaghan James P; Persidsky Yuri; Power Christopher; Rogers Thomas J; Royal Walter
NeuroAIDS, drug abuse, and inflammation: building collaborative research activities.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2006;1(4):351-99.
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2006: Persidsky Yuri; Poluektova Larisa
Immune privilege and HIV-1 persistence in the CNS.
Immunological reviews 2006;213():180-94.
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2006: Persidsky Yuri; Ramirez Servio H; Haorah James; Kanmogne Georgette D
Blood-brain barrier: structural components and function under physiologic and pathologic conditions.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2006;1(3):223-36.
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2006: Persidsky Yuri; Heilman David; Haorah James; Zelivyanskaya Marina; Persidsky Raisa; Weber Gregory A; Shimokawa Hiroaki; Kaibuchi Kozo; Ikezu Tsuneya
Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE).
Blood 2006;107(12):4770-80.
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2006: Potula Raghava; Haorah James; Knipe Bryan; Leibhart Jessica; Chrastil Jesse; Heilman David; Dou Huanyu; Reddy Rindha; Ghorpade Anuja; Persidsky Yuri
Alcohol abuse enhances neuroinflammation and impairs immune responses in an animal model of human immunodeficiency virus-1 encephalitis.
The American journal of pathology 2006;168(4):1335-44.
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2005: Haorah J; Knipe B; Leibhart J; Ghorpade A; Persidsky Y
Alcohol-induced oxidative stress in brain endothelial cells causes blood-brain barrier dysfunction.
Journal of leukocyte biology 2005;78(6):1223-32.
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2005: Persidsky Y; Potula R; Haorah J
Rodent model systems for studies of HIV-1 associated dementia.
Neurotoxicity research 2005;8(1-2):91-106.
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2005: Potula Raghava; Poluektova Larisa; Knipe Bryan; Chrastil Jesse; Heilman David; Dou Huanyu; Takikawa Osamu; Munn David H; Gendelman Howard E; Persidsky Yuri
Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis.
Blood 2005;106(7):2382-90.
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2005: Haorah James; Heilman David; Knipe Bryan; Chrastil Jesse; Leibhart Jessica; Ghorpade Anuja; Miller Donald W; Persidsky Yuri
Ethanol-induced activation of myosin light chain kinase leads to dysfunction of tight junctions and blood-brain barrier compromise.
Alcoholism, clinical and experimental research 2005;29(6):999-1009.
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2005: Ghorpade Anuja; Bruch Leslie; Persidsky Yuri; Chin Betty; Brown William H C; Borgmann Kathleen; Persidsky Raisa; Wu Li; Holter Spring; Cotter Robin; Faraci Jill; Heilman David; Meyer VaKara; Potter Jane F; Swindells Susan; Gendelman Howard E
Development of a rapid autopsy program for studies of brain immunity.
Journal of neuroimmunology 2005;163(1-2):135-44.
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2005: Ghorpade Anuja; Persidsky Yury; Swindells Susan; Borgmann Kathleen; Persidsky Raisa; Holter Spring; Cotter Robin; Gendelman Howard E
Neuroinflammatory responses from microglia recovered from HIV-1-infected and seronegative subjects.
Journal of neuroimmunology 2005;163(1-2):145-56.
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2005: Gendelman Howard E; Persidsky Yuri
Infections of the nervous system.
Lancet neurology 2005;4(1):12-3.
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2004: Batrakova Elena V; Zhang Yan; Li Yili; Li Shu; Vinogradov Sergei V; Persidsky Y; Alakhov Valery Yu; Miller Donald W; Kabanov Alexander V
Effects of pluronic P85 on GLUT1 and MCT1 transporters in the blood-brain barrier.
Pharmaceutical research 2004;21(11):1993-2000.
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2004: Haorah James; Heilman David; Diekmann Casey; Osna Natalia; Donohue Terrence M; Ghorpade Anuja; Persidsky Yuri
Alcohol and HIV decrease proteasome and immunoproteasome function in macrophages: implications for impaired immune function during disease.
Cellular immunology 2004;229(2):139-48.
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2004: Ryan Lisa A; Peng Hui; Erichsen David A; Huang Yunlong; Persidsky Yuri; Zhou You; Gendelman Howard E; Zheng Jialin
TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia.
Journal of neuroimmunology 2004;148(1-2):127-39.
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2004: Nukuna Adeline; Gendelman Howard E; Limoges Jenae; Rasmussen Jennifer; Poluektova Larisa; Ghorpade Anuja; Persidsky Yuri
Levels of human immunodeficiency virus type 1 (HIV-1) replication in macrophages determines the severity of murine HIV-1 encephalitis.
Journal of neurovirology 2004;10 Suppl 1():82-90.
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2003: Persidsky Yuri; Gendelman Howard E
Mononuclear phagocyte immunity and the neuropathogenesis of HIV-1 infection.
Journal of leukocyte biology 2003;74(5):691-701.
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2003: Suryadevara Radhika; Holter Spring; Borgmann Kathleen; Persidsky Raisa; Labenz-Zink Christine; Persidsky Yuri; Gendelman Howard E; Wu Li; Ghorpade Anuja
Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: links to HIV-1 dementia.
Glia 2003;44(1):47-56.
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2003: Xiong Huangui; Boyle Jeffery; Winkelbauer Matthew; Gorantla Santhi; Zheng Jialin; Ghorpade Anuja; Persidsky Yuri; Carlson Kimberly A; Gendelman Howard E
Inhibition of long-term potentiation by interleukin-8: implications for human immunodeficiency virus-1-associated dementia.
Journal of neuroscience research 2003;71(4):600-7.
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2003: Anderson E R; Boyle J; Zink W E; Persidsky Y; Gendelman H E; Xiong H
Hippocampal synaptic dysfunction in a murine model of human immunodeficiency virus type 1 encephalitis.
Neuroscience 2003;118(2):359-69.
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2002: Persidsky Yuri; Gendelman Howard E
Murine models for human immunodeficiency virus type 1-associated dementia: the development of new treatment testing paradigms.
Journal of neurovirology 2002;8 Suppl 2():49-52.
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2002: Poluektova Larisa Y; Munn David H; Persidsky Yuri; Gendelman Howard E
Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):3941-9.
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2002: Zink Walter E; Anderson Eric; Boyle Jeffrey; Hock Lynette; Rodriguez-Sierra Jorge; Xiong Huangui; Gendelman Howard E; Persidsky Yuri
Impaired spatial cognition and synaptic potentiation in a murine model of human immunodeficiency virus type 1 encephalitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(6):2096-105.
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2001: Poluektova L; Moran T; Zelivyanskaya M; Swindells S; Gendelman H E; Persidsky Y
The regulation of alpha chemokines during HIV-1 infection and leukocyte activation: relevance for HIV-1-associated dementia.
Journal of neuroimmunology 2001;120(1-2):112-28.
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2001: Zheng J; Thylin M R; Persidsky Y; Williams C E; Cotter R L; Zink W; Ryan L; Ghorpade A; Lewis K; Gendelman H E
HIV-1 infected immune competent mononuclear phagocytes influence the pathways to neuronal demise.
Neurotoxicity research 2001;3(5):461-84.
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2001: Zheng J; Thylin M R; Cotter R L; Lopez A L; Ghorpade A; Persidsky Y; Xiong H; Leisman G B; Che M H; Gendelman H E
HIV-1 infected and immune competent mononuclear phagocytes induce quantitative alterations in neuronal dendritic arbor: relevance for HIV-1-associated dementia.
Neurotoxicity research 2001;3(5):443-59.
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2001: Ghorpade A; Persidskaia R; Suryadevara R; Che M; Liu X J; Persidsky Y; Gendelman H E
Mononuclear phagocyte differentiation, activation, and viral infection regulate matrix metalloproteinase expression: implications for human immunodeficiency virus type 1-associated dementia.
Journal of virology 2001;75(14):6572-83.
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2001: Persidsky Y; Limoges J; Rasmussen J; Zheng J; Gearing A; Gendelman H E
Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFalpha inhibitor in SCID mice with HIV-1 encephalitis.
Journal of neuroimmunology 2001;114(1-2):57-68.
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2001: Limoges J; Poluektova L; Ratanasuwan W; Rasmussen J; Zelivyanskaya M; McClernon D R; Lanier E R; Gendelman H E; Persidsky Y
The efficacy of potent anti-retroviral drug combinations tested in a murine model of HIV-1 encephalitis.
Virology 2001;281(1):21-34.
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2001: Zink W E; Boyle J; Persidsky Y; Xiong H; Gendelman H E
Model systems for assessing cognitive function: implications for HIV-1 infection and drugs of abuse.
Advances in experimental medicine and biology 2001;493():7-27.
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2000: Persidsky Y; Zheng J; Miller D; Gendelman H E
Mononuclear phagocytes mediate blood-brain barrier compromise and neuronal injury during HIV-1-associated dementia.
Journal of leukocyte biology 2000;68(3):413-22.
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2000: Xiong H; Zeng Y C; Lewis T; Zheng J; Persidsky Y; Gendelman H E
HIV-1 infected mononuclear phagocyte secretory products affect neuronal physiology leading to cellular demise: relevance for HIV-1-associated dementia.
Journal of neurovirology 2000;6 Suppl 1():S14-23.
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2000: Limoges J; Persidsky Y; Poluektova L; Rasmussen J; Ratanasuwan W; Zelivyanskaya M; McClernon D R; Lanier E R; Gendelman H E
Evaluation of antiretroviral drug efficacy for HIV-1 encephalitis in SCID mice.
Neurology 2000;54(2):379-89.
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1999: Zink W E; Zheng J; Persidsky Y; Poluektova L; Gendelman H E
The neuropathogenesis of HIV-1 infection.
FEMS immunology and medical microbiology 1999;26(3-4):233-41.
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1999: Persidsky Y; Ghorpade A; Rasmussen J; Limoges J; Liu X J; Stins M; Fiala M; Way D; Kim K S; Witte M H; Weinand M; Carhart L; Gendelman H E
Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis.
The American journal of pathology 1999;155(5):1599-611.
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1999: Zheng J; Thylin M R; Ghorpade A; Xiong H; Persidsky Y; Cotter R; Niemann D; Che M; Zeng Y C; Gelbard H A; Shepard R B; Swartz J M; Gendelman H E
Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia.
Journal of neuroimmunology 1999;98(2):185-200.
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1998: Gendelman H E; Zheng J; Coulter C L; Ghorpade A; Che M; Thylin M; Rubocki R; Persidsky Y; Hahn F; Reinhard J; Swindells S
Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus-associated dementia.
The Journal of infectious diseases 1998;178(4):1000-7.
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1998: Davis V; Persidskaia R; Baca-Regen L; Itoh Y; Nagase H; Persidsky Y; Ghorpade A; Baxter B T
Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(10):1625-33.
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1998: Grange J J; Baca-Regen L M; Nollendorfs A J; Persidsky Y; Sudan D L; Baxter B T
Protein kinase C isoforms in human aortic smooth muscle cells.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 1998;27(5):919-26; discussion 926-7.
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1998: Ghorpade A; Xia M Q; Hyman B T; Persidsky Y; Nukuna A; Bock P; Che M; Limoges J; Gendelman H E; Mackay C R
Role of the beta-chemokine receptors CCR3 and CCR5 in human immunodeficiency virus type 1 infection of monocytes and microglia.
Journal of virology 1998;72(4):3351-61.
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1998: Ghorpade A; Nukuna A; Che M; Haggerty S; Persidsky Y; Carter E; Carhart L; Shafer L; Gendelman H E
Human immunodeficiency virus neurotropism: an analysis of viral replication and cytopathicity for divergent strains in monocytes and microglia.
Journal of virology 1998;72(4):3340-50.
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1997: Persidsky Y; Buttini M; Limoges J; Bock P; Gendelman H E
An analysis of HIV-1-associated inflammatory products in brain tissue of humans and SCID mice with HIV-1 encephalitis.
Journal of neurovirology 1997;3(6):401-16.
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1997: Persidsky Y; Gendelman H E
Development of laboratory and animal model systems for HIV-1 encephalitis and its associated dementia.
Journal of leukocyte biology 1997;62(1):100-6.
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1997: Limoges J; Persidsky Y; Bock P; Gendelman H E
Dexamethasone therapy worsens the neuropathology of human immunodeficiency virus type 1 encephalitis in SCID mice.
The Journal of infectious diseases 1997;175(6):1368-81.
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1997: Persidsky Y; Stins M; Way D; Witte M H; Weinand M; Kim K S; Bock P; Gendelman H E; Fiala M
A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3499-510.
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1997: Gendelman H E; Persidsky Y; Ghorpade A; Limoges J; Stins M; Fiala M; Morrisett R
The neuropathogenesis of the AIDS dementia complex.
AIDS (London, England) 1997;11 Suppl A():S35-45.
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1996: Persidsky Y; Limoges J; McComb R; Bock P; Baldwin T; Tyor W; Patil A; Nottet H S; Epstein L; Gelbard H; Flanagan E; Reinhard J; Pirruccello S J; Gendelman H E
Human immunodeficiency virus encephalitis in SCID mice.
The American journal of pathology 1996;149(3):1027-53.
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1996: Nottet H S; Persidsky Y; Sasseville V G; Nukuna A N; Bock P; Zhai Q H; Sharer L R; McComb R D; Swindells S; Soderland C; Gendelman H E
Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(3):1284-95.
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1995: Persidsky Y; Nottet H S; Sasseville V G; Epstein L G; Gendelman H E
The development of animal model systems for HIV-1 encephalitis and its associated dementia.
Journal of neurovirology 1995;1(3-4):229-43.
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1995: Nottet H S; Jett M; Flanagan C R; Zhai Q H; Persidsky Y; Rizzino A; Bernton E W; Genis P; Baldwin T; Schwartz J
A regulatory role for astrocytes in HIV-1 encephalitis. An overexpression of eicosanoids, platelet-activating factor, and tumor necrosis factor-alpha by activated HIV-1-infected monocytes is attenuated by primary human astrocytes.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(7):3567-81.
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